CN1911255A - Anti-oxidation tech. for wall-breaked glossy ganoderma spore powder - Google Patents
Anti-oxidation tech. for wall-breaked glossy ganoderma spore powder Download PDFInfo
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- CN1911255A CN1911255A CN 200610040992 CN200610040992A CN1911255A CN 1911255 A CN1911255 A CN 1911255A CN 200610040992 CN200610040992 CN 200610040992 CN 200610040992 A CN200610040992 A CN 200610040992A CN 1911255 A CN1911255 A CN 1911255A
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- ganoderma lucidum
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Abstract
An antioxidizing technique for the wall-broken ganoderma spore powder features that an edible powder is mixed with the wall-broken ganoderma spore powder to wrap the oily components easy to be oxidized, such as ganoderic triterpene and unsaturated fatty acid, for isolating them from oxygen.
Description
Technical field
The present invention relates to contain the preparation method of raw-material medicinal preparation, especially belong to the Sporoderm-broken Ganoderma Lucidum Spore powder anti-oxidation tech.
Background technology
Ganoderma since ancient times among the people be exactly a kind of medicine-food two-purpose fungus, Ganoderma spore contains than the Ganoderma special compositions such as peptidoglycan, ribosidoadenine, protein, enzyme and selenium element of horn of plenty more.Because the epidermis of Ganoderma spore is made of the hard chitin of one deck, water insoluble, lean on the digestive system of human body self can't destroy this epidermis, also just can't absorb active ingredient contained in the Ganoderma spore, therefore, ganoderma lucidium spore powder wall breaking becomes the main manufacturing process of Ganoderma spore powder.Ganoderma spore powder behind the breaking cellular wall contains the whole hereditary material of Ganoderma, and contains the alkaloid material that the cultivating ganoderma sporophore does not have, and its effect is equivalent to 75 times of Ganoderma sporophore, and is easily absorbed by the body.
But owing to compositions such as Ganoderma triterpenoids contained in the cell of Ganoderma spore, unsaturated fatty acids, being grease-like character exists, after the cell wall of Ganoderma spore is subjected to outside destroy, these active ingredients are overflowed outside the wall, directly with outside air contact, oxidated easily and cause the product active ingredient to change and affect the treatment.
Usually the scheme that solves has:
1, fills nitrogen: in packing of product bag, charge into a certain amount of nitrogen, thereby squeeze away oxygen wherein.
2, oxygen barrier: adopt vacuum-packed form, take the air in the packaging bag away, make product under vacuum state, be preserved.
These two kinds of ways all require packaging bag to have very high sealing, the packing cost height.Owing to the active ingredient height of Ganoderma spore powder, the amount of at every turn taking is few simultaneously, and independent packaging had both increased cost, had also increased the Ganoderma spore powder that adheres on the packaging, caused waste.
Summary of the invention
The object of the present invention is to provide a kind of convenient and easy can be with Sporoderm-broken Ganoderma Lucidum Spore powder and air insulated, it is oxidized that wherein active ingredient is difficult for, to prolong the Sporoderm-broken Ganoderma Lucidum Spore powder Sporoderm-broken Ganoderma Lucidum Spore powder anti-oxidation tech of effect duration.
A kind of Sporoderm-broken Ganoderma Lucidum Spore powder anti-oxidation tech of the present invention, its invention main points are to be mixed into edible powder in Sporoderm-broken Ganoderma Lucidum Spore powder, Sporoderm-broken Ganoderma Lucidum Spore powder: the mixing ratio of edible powder is 1: 0.1-10.
Obtaining the better mixing ratio through experiment is 1: 0.2-4, best mixing ratio is 1: 0.5-2.
Edible powder is meant that particle diameter is the powder (being generally 200 mesh sieves) below 10 microns.
As everyone knows, after the cell wall of Ganoderma spore is subjected to outside destroy, the interior a large amount of active ingredient of spore is grease-like and overflows outside the wall, oxidized easily, this is the defective that Sporoderm-broken Ganoderma Lucidum Spore powder exists, the present invention looks for another way, utilize easily adsorptivity of greasy another characteristic----, adding other edible powder wraps up it, with Sporoderm-broken Ganoderma Lucidum Spore powder and oxygen gases separated, it is oxidized that wherein active ingredient is difficult for, and by the blister or the powder dissolving of wrapping up under the effect of gastric acid, makes the contained active ingredient of Ganoderma spore be able to be absorbed by human body when taking.
In order to give full play to the therapeutic efficiency of Ganoderma, the present invention can also be by following scheme, reasonably combinedly goes into various ministerial drugs and reaches different therapeutic purposes.
Can add the superfine powder of rare edible and medical fungis such as Ganoderma, Ganoderma, Coriolous Dersicolor (Fr.) Quel, Antrodia camphorata, Cordyceps, Agaricus blazei Murrill, Auricularia, Hericium erinaceus (Bull. Ex Fr.) Pers., Phellinus igniarius (L. ex Fr.) Quel., Poria and water is carried or the alcohol extraction extract powder.
Or the superfine powder of Folium Camelliae sinensis such as green tea, black tea and water is carried or the alcohol extraction extract powder.
Chinese medicine ultra-fine powders such as Radix Ginseng, Radix Panacis Quinquefolii, Fructus Lycii, Fructus Schisandrae Chinensis, Semen Ziziphi Spinosae, Fructus Tritici Levis, Semen Platycladi, Radix Polygalae, Poria, Herb Gynostemmae Pentaphylli, Aloe and water is carried or the alcohol extraction extract powder.
Also can add materials such as dextrin, starch, lactose, mannitol, Sporoderm-broken Ganoderma Lucidum Spore powder is had good embedding effect, can play antioxidation.
The mixed process of Sporoderm-broken Ganoderma Lucidum Spore powder and edible powder is: after the Ganoderma spore powder behind the breaking cellular wall is crossed the 100--300 mesh sieve, insert mixer, add the edible powder, can add a kind of, also can add multiplely simultaneously, mix after 30--45 minute, cross 80 eye mesh screens and sieve.
The invention has the advantages that, utilize greasy easy adsorptivity, adding other edible powder wraps up oil readily oxidizable substances such as Ganoderma triterpenoids, unsaturated fatty acids, active ingredient and oxygen gases separated with oil easy oxidation in the Sporoderm-broken Ganoderma Lucidum Spore powder, by blister or the dissolving of the powder that under the effect of gastric acid, wraps up, make the contained active ingredient of Ganoderma spore be able to be absorbed when taking by human body.This processing method is simple, can fundamentally solve Sporoderm-broken Ganoderma Lucidum Spore powder oxidized problem easily again, and the shelf-life can reach more than 24 months.
The specific embodiment
Embodiment 1, and the log Ganoderma spore powder is after open-air bagging is gathered, and naked eyes are chosen bulk impurity, no longer bonds to spore powder in dry about 5 hours under 80 ℃ of conditions, and sieves with 200 mesh sieves, removes impurity; Adopt the mechanical breaking-wall method method, with micronizing breaking cellular wall unit work 30 to 50 minutes, this moment, the sporoderm-broken rate of Ganoderma spore powder can reach more than 99%, and vacuum decompression is dried to moisture less than 6% under 40 degree conditions, and vacuum pressure is 0.04 to 0.06MPa.Dried Ganoderma spore powder is crossed 120 mesh sieves; insert mixer; by Sporoderm-broken Ganoderma Lucidum Spore powder: edible powder (wherein edible powder can for the superfine powder of rare edible and medical fungis such as Ganoderma, Ganoderma, Coriolous Dersicolor (Fr.) Quel, Antrodia camphorata, Cordyceps, Agaricus blazei Murrill, Auricularia, Hericium erinaceus (Bull. Ex Fr.) Pers., Phellinus igniarius (L. ex Fr.) Quel., Poria and water is carried or the alcohol extraction extract powder in one or more carry out compatibility) mixing ratio be 1: 0.1-10; add the Ganoderma superfine powder below 10 microns; mix after 30--45 minute, cross 80 eye mesh screens and sieve.Can make multiple dosage forms such as capsule, granule, tablet, product has the raising immunity, and the Ganoderma superfine powder that is increased not only can play antioxidation, also can play synergic effect simultaneously.
Embodiment 2, and the log Ganoderma spore powder is after open-air bagging is gathered, and naked eyes are chosen bulk impurity, no longer bond to spore powder in dry about 5 hours under 80 ℃ of conditions, and sieve with 200 mesh sieves, remove impurity; Adopt the mechanical breaking-wall method method, with micronizing breaking cellular wall unit work 30 to 50 minutes, this moment, the sporoderm-broken rate of Ganoderma spore powder can reach more than 99%, Sporoderm-broken Ganoderma Lucidum Spore powder is crossed 200 mesh sieves, insert mixer, by Sporoderm-broken Ganoderma Lucidum Spore powder: edible powder mixes ratio is 1: 4, (edible powder can be selected Radix Ginseng, Radix Panacis Quinquefolii, Fructus Lycii, Fructus Schisandrae Chinensis, Semen Ziziphi Spinosae, Fructus Tritici Levis, Semen Platycladi, Radix Polygalae, Poria, Herb Gynostemmae Pentaphylli, Chinese medicine ultra-fine powders such as Aloe and water is carried or the alcohol extraction extract powder in one or more carry out compatibility), add the Ganoderma below 10 microns simultaneously, Fructus Lycii, the water of Poria etc. is carried or the alcohol extraction extract powder, Ganoderma wherein: Fructus Lycii: Poria is 5: 3: 2, mix after 30--45 minute, cross the 80--100 eye mesh screen and sieve.Can make multiple dosage forms such as capsule, granule, tablet, product have protect the liver, radiation resistance, the ministerial drug that is increased not only can play antioxidation, also can play synergic effect simultaneously.
Embodiment 3, Ganoderma sleeping capsule is that Sporoderm-broken Ganoderma Lucidum Spore powder is crossed 200 mesh sieves, insert mixer, by Sporoderm-broken Ganoderma Lucidum Spore powder: edible powder mixes ratio is 1: 2, the water that adds Fructus Schisandrae Chinensis below 10 microns, Semen Ziziphi Spinosae etc. is simultaneously carried or the alcohol extraction extract powder, Fructus Schisandrae Chinensis wherein: Semen Ziziphi Spinosae is 3: 5.5, mixes after 30--45 minute, crosses the 80--100 eye mesh screen and sieves.Can make multiple dosage forms such as capsule, granule, tablet, product has the sleep of improvement effect, and the ministerial drug that is increased not only can play antioxidation, also can play synergic effect simultaneously.It is identical with last example that all the other do not state part.
Embodiment 4, Ganoderma spore powder is crossed 300 mesh sieves, insert mixer, by Sporoderm-broken Ganoderma Lucidum Spore powder: edible powder mixes ratio is 1: 0.1, add in dextrin below 10 microns, starch, the lactose one or more and carry out compatibility, mix after 30--45 minute, cross the 80--100 eye mesh screen and sieve.Can make multiple dosage forms such as capsule, granule, tablet.It is identical with embodiment 1 that all the other do not state part.
Embodiment 5, and Ganoderma spore powder is crossed 200 mesh sieves, insert mixer, by Sporoderm-broken Ganoderma Lucidum Spore powder: edible powder mixes ratio is 1: 10, add the superfine powder of the green tea below 10 microns and water is carried or the alcohol extraction extract powder, mixes after 30--45 minute, mistake 80--100 eye mesh screen sieves.Can make multiple dosage forms such as capsule, granule, tablet, product has the sobering-up functions of refreshing oneself.It is identical with last example that all the other do not state part.
Claims (8)
1, a kind of Sporoderm-broken Ganoderma Lucidum Spore powder anti-oxidation tech is characterized in that being mixed into edible powder, Sporoderm-broken Ganoderma Lucidum Spore powder in Sporoderm-broken Ganoderma Lucidum Spore powder: the mixing ratio of edible powder is 1: 0.1-10.
2, a kind of Sporoderm-broken Ganoderma Lucidum Spore powder anti-oxidation tech according to claim 1, it is characterized in that Sporoderm-broken Ganoderma Lucidum Spore powder: the mixing ratio of edible powder is 1: 0.2-4.
3, a kind of Sporoderm-broken Ganoderma Lucidum Spore powder anti-oxidation tech according to claim 1, it is characterized in that Sporoderm-broken Ganoderma Lucidum Spore powder: the mixing ratio of edible powder is 1: 0.5-2.
4, a kind of Sporoderm-broken Ganoderma Lucidum Spore powder anti-oxidation tech according to claim 1 is characterized in that the edible powder is meant that particle diameter is the powder below 10 microns.
5, a kind of Sporoderm-broken Ganoderma Lucidum Spore powder anti-oxidation tech according to claim 1 is characterized in that the edible powder is meant the superfine powder of rare edible and medical fungi such as Ganoderma, Ganoderma, Coriolous Dersicolor (Fr.) Quel, Antrodia camphorata, Cordyceps, Agaricus blazei Murrill, Auricularia, Hericium erinaceus (Bull. Ex Fr.) Pers., Phellinus igniarius (L. ex Fr.) Quel., Poria and water is carried or the alcohol extraction extract powder.
6, a kind of Sporoderm-broken Ganoderma Lucidum Spore powder anti-oxidation tech according to claim 1 is characterized in that the edible powder is meant the superfine powder of Folium Camelliae sinensis and water is carried or the alcohol extraction extract powder.
7, a kind of Sporoderm-broken Ganoderma Lucidum Spore powder anti-oxidation tech according to claim 1 is characterized in that the edible powder is meant Chinese crude drug or medicine food dual purpose plant such as Radix Ginseng, Radix Panacis Quinquefolii, Fructus Lycii, Fructus Schisandrae Chinensis, Semen Ziziphi Spinosae, Folium Ginkgo, Semen Coicis, green tea, Poria, Herb Gynostemmae Pentaphylli, aloetic superfine powder and water is carried or the alcohol extraction extract powder.
8, a kind of Sporoderm-broken Ganoderma Lucidum Spore powder anti-oxidation tech according to claim 1, the mixed process that it is characterized in that Sporoderm-broken Ganoderma Lucidum Spore powder and edible powder is: after the Ganoderma spore powder behind the breaking cellular wall is crossed the 100--300 mesh sieve, insert mixer, add the edible powder, can add a kind of, also can add multiplely simultaneously, mix after 30--45 minute, cross 80 eye mesh screens and sieve.
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Cited By (16)
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CN101502620A (en) * | 2009-01-14 | 2009-08-12 | 邢炳荣 | Pure natural concentrated health-care capsule for protecting liver, expelling toxin and lowering lipid |
CN101797272A (en) * | 2010-02-10 | 2010-08-11 | 广东省微生物研究所 | Fungus compound agent with antifatigue function |
CN101935586A (en) * | 2010-09-28 | 2011-01-05 | 江苏江大源生态生物科技有限公司 | Method for extracting ganoderma spore oil with supercritical CO2 |
CN101618087B (en) * | 2009-08-03 | 2011-11-23 | 无限极(中国)有限公司 | Health-care food with function of improving climacteric |
CN103054008A (en) * | 2013-02-04 | 2013-04-24 | 福建仙芝楼生物科技有限公司 | Lucid ganoderma sleep-aiding capsule and preparation method thereof |
CN103169737A (en) * | 2013-03-19 | 2013-06-26 | 佛山市顺德区今日景艺生物科技有限公司 | Composite of Antrodia camphorata entity and shell-broken ganoderma lucidum spore powder and application thereof in immune adjustment |
CN103432176A (en) * | 2013-08-24 | 2013-12-11 | 江苏神华药业有限公司 | Compound antrodia camphorata-ganoderma lucidum composition and preparation method thereof |
CN103599139A (en) * | 2013-11-28 | 2014-02-26 | 江西仙客来生物科技有限公司 | Ganoderma lucidum shell-broken spore powder-agaricus blazei murill capsule |
CN105142424A (en) * | 2013-04-26 | 2015-12-09 | 李大熙 | Cereal containing hericium erinaceum and method for making same |
CN105455116A (en) * | 2015-11-23 | 2016-04-06 | 南京贝杉国际贸易有限公司 | Functional food for preventing senile dementia and delaying progression of senile dementia and preparation method thereof |
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CN109123611A (en) * | 2018-08-03 | 2019-01-04 | 安徽康宸药业有限公司 | A kind of preparation method of the ganoderma spove powder electuary with strengthen immunity and anti-oxidation function |
WO2019024019A1 (en) * | 2017-08-02 | 2019-02-07 | 江苏安惠生物科技有限公司 | Lung nourishing capsule for enhanced immunity |
CN109349640A (en) * | 2018-12-10 | 2019-02-19 | 金木集团有限公司 | A kind of health-caring capsule improving chemical damage |
CN113197954A (en) * | 2021-04-15 | 2021-08-03 | 广州逸仙生命健康科技有限公司 | Antioxidant wall-broken ganoderma lucidum spore powder and preparation method thereof |
CN116144446A (en) * | 2021-11-19 | 2023-05-23 | 泸州老窖股份有限公司 | Health care wine for improving sleep function |
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2006
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CN101502620A (en) * | 2009-01-14 | 2009-08-12 | 邢炳荣 | Pure natural concentrated health-care capsule for protecting liver, expelling toxin and lowering lipid |
CN101502620B (en) * | 2009-01-14 | 2013-03-20 | 邢炳荣 | Pure natural concentrated health-care capsule for protecting liver, expelling toxin and lowering lipid |
CN101618087B (en) * | 2009-08-03 | 2011-11-23 | 无限极(中国)有限公司 | Health-care food with function of improving climacteric |
CN101797272A (en) * | 2010-02-10 | 2010-08-11 | 广东省微生物研究所 | Fungus compound agent with antifatigue function |
CN101797272B (en) * | 2010-02-10 | 2012-07-04 | 广东省微生物研究所 | Fungus compound agent with antifatigue function |
CN101935586A (en) * | 2010-09-28 | 2011-01-05 | 江苏江大源生态生物科技有限公司 | Method for extracting ganoderma spore oil with supercritical CO2 |
CN103054008A (en) * | 2013-02-04 | 2013-04-24 | 福建仙芝楼生物科技有限公司 | Lucid ganoderma sleep-aiding capsule and preparation method thereof |
CN103169737B (en) * | 2013-03-19 | 2015-02-18 | 佛山市顺德区今日景艺生物科技有限公司 | Composite of Antrodia camphorata entity and shell-broken ganoderma lucidum spore powder and application thereof in immune adjustment |
CN103169737A (en) * | 2013-03-19 | 2013-06-26 | 佛山市顺德区今日景艺生物科技有限公司 | Composite of Antrodia camphorata entity and shell-broken ganoderma lucidum spore powder and application thereof in immune adjustment |
CN105142424A (en) * | 2013-04-26 | 2015-12-09 | 李大熙 | Cereal containing hericium erinaceum and method for making same |
CN103432176A (en) * | 2013-08-24 | 2013-12-11 | 江苏神华药业有限公司 | Compound antrodia camphorata-ganoderma lucidum composition and preparation method thereof |
CN103432176B (en) * | 2013-08-24 | 2016-06-01 | 江苏神华药业有限公司 | A kind of compound antrodia camphorata-ganodermalucidum lucidum composition and its preparation method |
CN103599139A (en) * | 2013-11-28 | 2014-02-26 | 江西仙客来生物科技有限公司 | Ganoderma lucidum shell-broken spore powder-agaricus blazei murill capsule |
CN105455116A (en) * | 2015-11-23 | 2016-04-06 | 南京贝杉国际贸易有限公司 | Functional food for preventing senile dementia and delaying progression of senile dementia and preparation method thereof |
WO2019024019A1 (en) * | 2017-08-02 | 2019-02-07 | 江苏安惠生物科技有限公司 | Lung nourishing capsule for enhanced immunity |
CN107961252A (en) * | 2017-12-08 | 2018-04-27 | 芜湖市诺康生物科技有限公司 | A kind of preparation method of ganoderma spove powder capsule |
CN109123611A (en) * | 2018-08-03 | 2019-01-04 | 安徽康宸药业有限公司 | A kind of preparation method of the ganoderma spove powder electuary with strengthen immunity and anti-oxidation function |
CN109349640A (en) * | 2018-12-10 | 2019-02-19 | 金木集团有限公司 | A kind of health-caring capsule improving chemical damage |
CN113197954A (en) * | 2021-04-15 | 2021-08-03 | 广州逸仙生命健康科技有限公司 | Antioxidant wall-broken ganoderma lucidum spore powder and preparation method thereof |
CN116144446A (en) * | 2021-11-19 | 2023-05-23 | 泸州老窖股份有限公司 | Health care wine for improving sleep function |
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