CN1907374A - Chinese medicinal composition for treating oral disease - Google Patents
Chinese medicinal composition for treating oral disease Download PDFInfo
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- CN1907374A CN1907374A CN 200610112041 CN200610112041A CN1907374A CN 1907374 A CN1907374 A CN 1907374A CN 200610112041 CN200610112041 CN 200610112041 CN 200610112041 A CN200610112041 A CN 200610112041A CN 1907374 A CN1907374 A CN 1907374A
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- chinese medicine
- medicine composition
- herba houttuyniae
- xylitol
- oral
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Abstract
The invention discloses a medicinal composition for preventing and treating oral diseases, which comprises raw materials of xylitol, cordate houttuynia extract and water melon frost as the basis formulation.
Description
Technical field
The invention belongs to the pharmaceutical technology field, be specifically related to a kind of Chinese medicine composition and in the application that prevents and treats aspect the oral disease, said composition basis prescription is made up of xylitol, Herba Houttuyniae extract and watermelon crystal.
Background technology
Xylitol
Xylitol is a kind of pentose alcohol, is the normal intermediate product of xylose metabolism, and profile is the crystallinity white powder, extensively is present in the plants such as the group food of fruit, vegetable, frumentum, mushroom and timber, Caulis et Folium Oryzae, corn cob.It can be used as the extensive use in industry such as chemical industry, food, medicine of sweeting agent, nutrient and medicament.Four big healthy definition of xylitol: 1. additional heat.The quantity of heat production and the glucose of xylitol are similar, can be used as the nutritional drugs of additional heat clinically.2. improve carbohydrate metabolism.Xylitol metabolism does not in vivo rely on the participation of insulin, directly permeate through cell membranes involved in sugar metabolism and do not increase blood sugar concentration, and its sweet taste and glucose are similar, also can promote insulin to secrete on a small quantity, so can be used for the succedaneum of diabetics as sugar.3. inhibition ketoplasia.Xylitol can make blood plasma fatty acid generate minimizing, the drug combination of ketoacidosis when can be used as diabetes, surgery anesthesia.4. prevent and treat dental caries.Xylitol can suppress to cause the bacteria breed of dental caries growth, thereby reaches good anti-dental caries effect.
Herba Houttuyniae
Herba Houttuyniae is commonly called as hog snout hole, Herba Houttuyniae, is the root or the herb of Saururaceae herbaceos perennial Herba Houttuyniae." integration of edible and medicinal herbs ", China just ate Herba Houttuyniae before more than 2,000 years as the wild herbs assistant.Passing on from one to another the The Spring and Autumn Period gets over the king and colludes to trample and endure hardships to accomplish some ambition, refine in meaning pursues a goal with determination, and once leads everybody to select Herba Houttuyniae and eat it, useless waste to allay one's hunger; Rise during Wei Jin, Herba Houttuyniae is just formally as medicinal, with the medical ancient books and records of name income of " Herba Houttuyniae ".In historical upheaval development, it just plays the part of medicine, the dual-purpose dual role of food always, for common people's health care, preventing and curing diseases bringing into play acts on.More and more uphold nature, pursuit are very plain along with modern people, and in various places (especially China southwest), Herba Houttuyniae wild or tame kind has become " the main road wild herbs " of having a sudden rise in social status on the popular dining table.
Herba Houttuyniae is cooked, and eats the best raw, but its fragrance uniqueness, the other tool of mouthfeel, the agreeable to the taste people of local flavor.Cold and dressed with sauce going with rice or bread makes National People's Congress appetizing mouthful, appetite stimulator, improves digestive function, also have stir-fry and eat, fry in shallow oil soup, cook congee, the different Dietotherapy methods of fricassee.
Herba Houttuyniae is used as medicine, the traditional Chinese medical science is thought its acrid in the mouth, cold, skin ulcer, promoting urination to remove dampness, invigorating the stomach and promoting digestion are treated in energy heat-clearing and toxic substances removing, the detumescence of row's pain, with controlling excess-heat, pyretic toxicity, damp, disease heat is the lung abscess suffered from, sore swollen toxin, hemorrhoidal hemorrhage, retention of heat in the spleen and stomach etc., list is used or the compatibility compound recipe, the equal determined curative effect of the use of oral administration and externally or multiple Dietotherapy method among the people.Pharmacological research, the Herba Houttuyniae master contains volatile oil, multiple components such as decanoylacetaldehyde houttuynine sodium bisulfite, various Xenorhabduses, coccus, influenza virus, leptospira etc. there is the inhibition antibacterial action, and can improve the human immunity regulatory function, as in the Herba Houttuyniae liquid of 1: 40000 concentration, staphylococcus aureus is still had inhibitory action, so it has significant anti-inflammation usefulness.Dosage forms such as houttuynine sodium bisulfite has now been made sheet, pin, dashed, atomizing are widely used in the control of human body respiration, digestion, infectious diseases of urogenital system.
Have data to show, from Herba Houttuyniae, isolate a kind of cancer-resisting material abroad, except that to gastric cancer effectively, and medium and advanced lung cancer, chorionic epithelioma, malignant mole, rectal cancer also had certain control Accommodation.In Japan, Herba Houttuyniae is favored, be referred to as " ten medicines " traditionally, as the good vegetables of fashionable health care, think that Herba Houttuyniae has obviously effects such as antibiotic, antiinflammatory, aid digestion, heat clearing away, detoxifcation, antiallergic, radioprotective, cancer-resisting, except that adopting traditional Chinese prescription, medicative diet for food therapy, also use in functional health-care food modes such as (food such as tea, beverage add).
At present, houttuynine sodium bisulfite has been used for prevention, control and the assisting in preventing and treating of aspect diseases such as anemia, constipation, gastroenteritis, arteriosclerosis, hypertension, diabetes, allergic rhinitis, urticaria, multiple inflammation, cancer both at home and abroad, has indicated that Herba Houttuyniae still has practical DEVELOPMENT PROSPECT on disease is dispelled in nourishing healthy, diseases prevention.
Watermelon crystal
Watermelon crystal is the mature fruit of cucurbitaceous plant Citrullus vulgaris Citrulluis vulgaris Schrad. and the white crystalline powder that Natrii Sulfas processes from strand, and also is a kind of Chinese medicine, and its specific practice is: get fresh Citrullus vulgaris, cut a sheet along base of a fruit head and make top cover, cut out melon pulp and seed, Natrii Sulfas is inserted in the melon, cover top cover, insert firmly with bamboo let, put into earthen basin, build, put the shady and cool ventilation place, when waiting to separate out bloom, under the brush, separating out until no bloom is degree at any time.
The function of watermelon crystal is heat-clearing and toxic substances removing, reducing swelling and alleviating pain with curing mainly.Be used for laryngopharynx swelling and pain, aphtha of the mouth and tongue, gingival swelling and pain or hemorrhage, thrush, infantile thrush and slight burn and scald and wound hemorrhage; Acute and chronic pharyngolaryngitis, tonsillitis, stomatitis, oral ulcer is seen above-mentioned patient.
Summary of the invention
A kind of Chinese medicine composition of preventing and treating oral disease is characterized in that said composition serves as basis side with xylitol, Herba Houttuyniae extract and watermelon crystal, and its parts by weight are:
Xylitol 1-50
Herba Houttuyniae extract 0.01-10
Watermelon crystal 0.1-10
More preferably the parts by weight of compositions are:
Xylitol 1-10
Herba Houttuyniae extract 0.1-5
Watermelon crystal 0.1-5
More preferably the parts by weight of compositions are:
Xylitol 1-5
Herba Houttuyniae extract 0.1-2
Watermelon crystal 0.2-2
Chinese medicine composition of the present invention, one or more in can also other heat-clearing and detoxifying herb of compatibility are to heighten the effect of a treatment; Heat and toxic materials clearing away medicine specifically refers to pear, Flos Lonicerae, Flos Chrysanthemi Indici, Borneolum Syntheticum, Oleum menthae, Mentholum, FRUCTUS TERMINALIAE IMMATURUS, Fructus Momordicae, Indigo Naturalis, Tradescantia albiflora, the Radix Angelicae Dahuricae, Semen Oroxyli, Rhizoma Polygonati Odorati etc.; Wherein survival dose is conventional recommended amounts in each flavor, pear 30-50, Flos Lonicerae 10-15, Flos Chrysanthemi Indici 10-20, Borneolum Syntheticum 0.01-2, Oleum menthae 0.01-2, Mentholum 0.01-2, Borax 0.1-2, FRUCTUS TERMINALIAE IMMATURUS 6-12, Fructus Momordicae 6-12, Indigo Naturalis 1.5-3, Tradescantia albiflora 10-30, Radix Angelicae Dahuricae 6-15, Semen Oroxyli 10-20, Rhizoma Polygonati Odorati 10-20.
Chinese medicine composition of the present invention is in the application that prevents and treats aspect the oral disease, diseases such as control acute and chronic pharyngitis, acute tonsillitis, oral ulcer, stomatitis, gingival swelling and pain, disease is seen: laryngopharynx swelling and pain, hoarseness, laryngalgia, throat moth, erosion of the oral mucosa, aphtha of the mouth and tongue, toothache etc.
Chinese medicine composition of the present invention can be made various dosage forms on the medicament book according to conventional method, specifically refers to tablet, capsule, oral liquid, pill, granule, colloid, syrup, can also add to and make chewing gum and chewable tablet in the food; Its administering mode is oral or topical.
The concrete preparation technology of Herba Houttuyniae extract is as follows: get fresh Herba Houttuyniae, the squeezing extracting juice is standby.
Prescription 1: xylitol 50g, Herba Houttuyniae extract 10g, watermelon crystal 10g, pear 50g
Method for making: concentrating under reduced pressure becomes thick paste after getting the fried juice of pear, adds xylitol, Herba Houttuyniae extract and the watermelon crystal of recipe quantity, adds an amount of chewing gum bodying agent again, is pressed into chewing gum according to a conventional method.
Prescription 2: xylitol 5g, Herba Houttuyniae extract 0.1g, watermelon crystal 0.2g, FRUCTUS TERMINALIAE IMMATURUS 6g, Fructus Momordicae 6g, Oleum menthae 0.1g
Method for making: get FRUCTUS TERMINALIAE IMMATURUS and Fructus Momordicae with water extraction after, the extracting solution concentrating under reduced pressure becomes thick paste, adds xylitol, Herba Houttuyniae extract, watermelon crystal and the Oleum menthae of recipe quantity, adds auxiliary type agent and correctivess such as an amount of sucrose again, make granule according to a conventional method, repress is made sheet.
Prescription 3: xylitol 10g, Herba Houttuyniae extract 2g, watermelon crystal 5g, Flos Chrysanthemi Indici 20g, Borneolum Syntheticum 0.1g, Mentholum 0.5g
Method for making: Flos Chrysanthemi Indici with water extraction after, the extracting solution concentrating under reduced pressure becomes thick paste, adds xylitol, Herba Houttuyniae extract, watermelon crystal, Borneolum Syntheticum and the Mentholum of recipe quantity, adds auxiliary type agent and correctivess such as an amount of sucrose again, make granule according to a conventional method, repress is made sheet.
Prescription 4: xylitol 5g, Herba Houttuyniae extract 1g, watermelon crystal 2g, Radix Angelicae Dahuricae 10g, Semen Oroxyli 10g, Rhizoma Polygonati Odorati 10g
Method for making: the Radix Angelicae Dahuricae, Semen Oroxyli, Rhizoma Polygonati Odorati with water extraction after, the extracting solution concentrating under reduced pressure becomes thick paste, add recipe quantity xylitol, Herba Houttuyniae extract, watermelon crystal, add an amount of auxiliary type agent and correctives again, make oral liquid according to a conventional method.
Prescription 5: xylitol 10g, Herba Houttuyniae extract 5g, watermelon crystal 5g, pear 20g, Flos Lonicerae 10g
Method for making: get the fried juice of pear, Flos Lonicerae use water extraction, both solution merge concentrating under reduced pressure and become thick paste, and xylitol, Herba Houttuyniae extract and the watermelon crystal of adding recipe quantity add an amount of chewing gum bodying agent again, make chewing gum according to a conventional method.
Prescription 6: xylitol 5g, Herba Houttuyniae extract 0.1g, watermelon crystal 0.2g, Indigo Naturalis 3g, Tradescantia albiflora 10g
Method for making: Indigo Naturalis, Tradescantia albiflora with water extraction after, the extracting solution concentrating under reduced pressure becomes thick paste, add recipe quantity xylitol, Herba Houttuyniae extract, watermelon crystal, add an amount of auxiliary type agent and correctives again, make granule according to a conventional method, repress is made tablet.
Pharmacodynamic experiment:
Get prescription 4 and be divided into two groups, looked for the aspiration of oral disease (as: acute and chronic pharyngolaryngitis, tonsillitis, stomatitis, oral ulcer) to try 20 of trenchermans, test-meal (chewing), statistics paresthesia alleviateding time with prescription 5 samples that make.
4 result of the tests of writing out a prescription:
| Paresthesia alleviateding time (hour) | Case load (people) | Total effective rate (%) |
| 0.5 | 4 | 70％ |
| More than 1 hour | 3 |
5 result of the tests of writing out a prescription:
| Paresthesia alleviateding time (hour) | Case load (people) | Total effective rate (%) |
| 0.5 | 3 | 70％ |
| More than 1 hour | 4 |
The result shows that Chinese medicine composition of the present invention has tangible mitigation to the symptom of oral disease.
Claims (8)
1, a kind of Chinese medicine composition of preventing and treating oral disease is characterized in that said composition serves as basis side with xylitol, Herba Houttuyniae extract and watermelon crystal, and its parts by weight are:
Xylitol 1-50
Herba Houttuyniae extract 0.01-10
Watermelon crystal 0.1-10.
2,, it is characterized in that the parts by weight of said composition are according to the described Chinese medicine composition of claim 1:
Xylitol 1-10
Herba Houttuyniae extract 0.1-5
Watermelon crystal 0.1-5.
3,, it is characterized in that the parts by weight of said composition are according to the described Chinese medicine composition of claim 2:
Xylitol 1-5
Herba Houttuyniae extract 0.1-2
Watermelon crystal 0.2-2.
4,, it is characterized in that in can also other heat-clearing and detoxifying herb of compatibility one or more are to heighten the effect of a treatment according to the described Chinese medicine composition of claim 1-3.
5, according to the Chinese medicine composition of any one qualification among the claim 1-4 in the application that prevents and treats aspect the oral disease, be used to prevent and treat diseases such as acute and chronic pharyngitis, acute tonsillitis, oral ulcer, stomatitis, gingival swelling and pain, disease is seen: laryngopharynx swelling and pain, hoarseness, laryngalgia, throat moth, erosion of the oral mucosa, aphtha of the mouth and tongue, toothache etc.
6,, it is characterized in that heat and toxic materials clearing away medicine specifically refers to pear, Flos Lonicerae, Flos Chrysanthemi Indici, Borneolum Syntheticum, Oleum menthae, Mentholum, FRUCTUS TERMINALIAE IMMATURUS, Fructus Momordicae, Indigo Naturalis, Tradescantia albiflora, the Radix Angelicae Dahuricae, Semen Oroxyli, Rhizoma Polygonati Odorati according to the described Chinese medicine composition of claim 4; Wherein survival dose is conventional recommended amounts in each flavor, pear 20-50, Flos Lonicerae 10-15, Flos Chrysanthemi Indici 10-20, Borneolum Syntheticum 0.01-2, Oleum menthae 0.01-2, Mentholum 0.01-2, FRUCTUS TERMINALIAE IMMATURUS 6-12, Fructus Momordicae 6-12, Indigo Naturalis 1.5-3, Tradescantia albiflora 10-30, Radix Angelicae Dahuricae 6-15, Semen Oroxyli 10-20, Rhizoma Polygonati Odorati 10-20.
7,, it is characterized in that and to make various dosage forms on the medicament book according to conventional method that its administering mode is oral or topical according to the described Chinese medicine composition of claim 6.
8, according to the described Chinese medicine composition of claim 7, it is characterized in that specifically referring to tablet, capsule, oral liquid, pill, granule, colloid, syrup, can also add to and make chewing gum and chewable tablet in the food.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610112041 CN1907374A (en) | 2006-08-29 | 2006-08-29 | Chinese medicinal composition for treating oral disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610112041 CN1907374A (en) | 2006-08-29 | 2006-08-29 | Chinese medicinal composition for treating oral disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1907374A true CN1907374A (en) | 2007-02-07 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200610112041 Pending CN1907374A (en) | 2006-08-29 | 2006-08-29 | Chinese medicinal composition for treating oral disease |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101961085A (en) * | 2010-10-15 | 2011-02-02 | 李建华 | Mineralizing teeth-protecting xylitol and preparation method thereof |
| CN103271267A (en) * | 2013-06-09 | 2013-09-04 | 湖南飙歌生物技术有限公司 | Citrulli degelatinatum and xylitol mixture and preparation method and application thereof |
| CN104983933A (en) * | 2015-07-03 | 2015-10-21 | 长沙秋点兵信息科技有限公司 | Chinese herbal medicine throat lozenge containing mirabilitum praeparatum and preparation method of Chinese herbal medicine throat lozenge |
| CN109431882A (en) * | 2018-11-16 | 2019-03-08 | 柳州两面针股份有限公司 | Compound Chinese medicine extract is preparing the application in oral cavity nursing health products |
| CN110151713A (en) * | 2019-05-22 | 2019-08-23 | 苏州知时生物科技有限公司 | Plant oral mucosa fibrosis chewable tablets and preparation method thereof |
-
2006
- 2006-08-29 CN CN 200610112041 patent/CN1907374A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101961085A (en) * | 2010-10-15 | 2011-02-02 | 李建华 | Mineralizing teeth-protecting xylitol and preparation method thereof |
| CN101961085B (en) * | 2010-10-15 | 2012-10-03 | 李建华 | Mineralizing teeth-protecting xylitol and preparation method thereof |
| CN103271267A (en) * | 2013-06-09 | 2013-09-04 | 湖南飙歌生物技术有限公司 | Citrulli degelatinatum and xylitol mixture and preparation method and application thereof |
| CN104983933A (en) * | 2015-07-03 | 2015-10-21 | 长沙秋点兵信息科技有限公司 | Chinese herbal medicine throat lozenge containing mirabilitum praeparatum and preparation method of Chinese herbal medicine throat lozenge |
| CN109431882A (en) * | 2018-11-16 | 2019-03-08 | 柳州两面针股份有限公司 | Compound Chinese medicine extract is preparing the application in oral cavity nursing health products |
| CN110151713A (en) * | 2019-05-22 | 2019-08-23 | 苏州知时生物科技有限公司 | Plant oral mucosa fibrosis chewable tablets and preparation method thereof |
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| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
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Application publication date: 20070207 |