CN1899530A - Medicine for preventing and treating infectious laryngotracheitis of chicken - Google Patents
Medicine for preventing and treating infectious laryngotracheitis of chicken Download PDFInfo
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Abstract
The invention discloses a medicine for preventing and treating infectious laryngotracheitis of chicken. The traditional Chinese medicine is prepared from the following traditional Chinese medicines in a certain proportion: ephedra, radix isatidis, pyrrosia lingua, subprostrate sophora, airpotato yam, stephanotis chinensis, thunberg fritillary bulb, almond, scutellaria baicalensis, snakegourd fruit, blackberry lily, burdock, radix angelicae, gypsum, rhizoma anemarrhenae, schizonepeta, mint, divaricate saposhnikovia root, reed rhizome, earthworm, liquorice, platycodon grandiflorum, medicinal cyathula root and talc. Sun drying the above materials, pulverizing, grinding, mixing, and stirring. In clinical application, the medicine is soaked in boiling water for 30-60 min to dissolve out the effective components of the medicine and to facilitate the absorption of the medicine in chicken, and small amount of sugar and Vc is added to raise the medicine effect. The medicine has high clinical cure rate, no adverse reaction, no medicine residue and no hidden danger of drug resistance. The preparation method is simple, the use is convenient, and the preparation method can be widely applied to the chicken industry.
Description
Technical field:
The invention belongs to medicine and engineering in medicine technical field, particularly a kind of medicine of preventing and treating chicken infectious laryngotracheitis that relates to.
Background technology:
The scale poultry husbandry of China mostly is the drylot feeding mode of raising in cages, though improved the unit are number of animals raised, because of the chicken population density bigger; environmental pollution; the influence of factors such as improper ventilation exists and very easily brings out the drawback that the respiratory tract fowl disease takes place, at the beginning of annual autumn end, spring and be situation occurred frequently winter.Just take place as chicken infectious laryngotracheitis every year, this is a kind of viral acute respiratory infectious disease, become the about 80-90% of chicken infection rate, the about 20-30% of mortality rate does not wait, and its characteristic pathological changes is that the yellow-white viscous solution is arranged in respiratory mucosa hyperemia, swelling, the pipeline more; The microscopy epithelial cell all has inclusion body to exist in the karyon.Primary disease is propagated fast, and mortality rate is higher, mainly infects into chicken.The disclosed drug main that is used to prevent and treat chicken infectious laryngotracheitis will comprise vaccine, Western medicine and Chinese medicine three major types in the prior art.This vaccine virulence is strong and the biological nature of hereditary reversion arranged, generally need not or careful usefulness, its biological safety is poor, immune effect is undesirable, causes this disease to take place every year; Commercially available Western medicine does not still have the specific treatment medicine, generally adopts symptomatic therapy, but as using moroxydine+penicillin+streptomycin drinking-water mitigate the disease, reduce death, but curative effect is too poor, and has the potential sequel of developing immunity to drugs with drug residue; Though loosing etc., other commercially available herbal medicine such as tetrahydro-isoquinolin, laryngitis do not have the drawback of above-mentioned Western medicine, but constitute some defectives of existence on the and methods for using them at prescription, or because of not rigorous the affecting the treatment of prescription, or on application process, mostly Chinese powder medicine is fed by the direct spice of explanation, delayed the absorption of sick chicken to effective ingredient, prevention effect is also unsatisfactory.
Summary of the invention:
The object of the present invention is to provide a kind of determined curative effect, the cure rate height has no side effect, drug residue free, the medicine of the control chicken infectious laryngotracheitis that is difficult for developing immunity to drugs after chicken is taken.
The medicine of control chicken infectious laryngotracheitis provided by the invention is a kind of pure Chinese medicine composition powder, and the prescription composition is expressed as by weight:
Herba Ephedrae 5-15, Radix Isatidis 5-15, Folium Pyrrosiae 5-15, Radix Sophorae Tonkinensis 5-15, Rhizoma Dioscoreae Bulbiferae 5-15, Radix Stephaniae Cepharanthae 5-15, Bulbus Fritillariae Thunbergii 5-15, Semen Armeniacae Amarum 3-8, Radix Scutellariae 3-8, Fructus Trichosanthis 3-8, Rhizoma Belamcandae 3-8, Fructus Arctii 3-8, Radix Angelicae Dahuricae 3-8, Gypsum Fibrosum 8-20, Rhizoma Anemarrhenae 2-5, Herba Schizonepetae 2-5, Herba Menthae 2-5, Radix Saposhnikoviae 2-5, Rhizoma Phragmitis 2-5, Pheretima 2-5, Radix Glycyrrhizae 1-3, Radix Platycodonis 1-3, Radix Cyathulae 1-3, Talcum 3-6.The 60-80 mesh sieve is dried, pulverized to said medicine, and stirring gets final product.
The usage and dosage of medicine of the present invention is as follows:
A, method: claim medicated powder to pour in Porcelain Jar or the porcelain urn according to chicken group quantity, the state of an illness, consumption and (avoid with canisters such as ferrum, aluminum, to avoid reaction, affect the treatment), the 5-10 times of boiling water that adds the medicated powder amount again, cover mouth rapidly, soaked stewing 30-60 minute, can make the active ingredient of medicine fully dissolve and separate out like this, when treating that fluid temperature is reduced to 20-25 ℃, again by boiling water amount or amount of liquid medicine, the saccharide (glucose or white sugar) of adding 10% and 0.02% vitamin C, purpose is both to have replenished the chicken energy i (in vivo), also has certain Detoxication.The medicinal liquid for preparing once threw clothes, logotype 3-5 days for the chicken group before the dusk.
B, consumption: therapeutic dose 1-2g/ is only. day, preventive dose 0.5-1g/ is only. day, logotype 3-5 days.
Prescription is resolved:
Medicament composing prescription of the present invention is according to the traditional traditional Chinese veterinary medicine theory of motherland, designs through dialectical in conjunction with chicken infectious laryngotracheitis feelings characteristic.Chinese veterinarian thinks that chicken body failure of defensive QI to protect the body against pathogen is experienced epidemic disease heresy (virus), be fade-in gas, battalion, blood system, invade lung and disturb liver, accumulate in the pyretic toxicity, lung qi must not respectfully fall, and water channel must not lead to accent, thermoae fire-transformation, fire is contained the meat corruption, the absurd row of forcing blood, impairment of body fluid consumption liquid, the endogenous dampness stasis of blood is long-pending, due to the stasis of blood and reducing phlegm, stagnation of phlegm throat,, performance contains diseases such as blood exudate so breathing because of difficult, cough with asthma and expectoration.Therefore, should establish heat-clearing and toxic substances removing, relieving cough and asthma, eliminating phlegm and the tonneau throat is the rule of treatment.So establishing the 7 flavor medicine combinations among the strong ones of Herba Ephedrae, Radix Isatidis, Folium Pyrrosiae, Radix Sophorae Tonkinensis, Rhizoma Dioscoreae Bulbiferae, Radix Stephaniae Cepharanthae, Bulbus Fritillariae Thunbergii in the prescription is that monarch drug is formed main force's square formation, guarantees effective efficacy of a drug of heat-clearing and toxic substances removing of the present invention, depressed lung-energy dispersing, relieving cough and resolving phlegm, removing heat from blood sore-throat relieving; Catching under the prerequisite of this principal contradiction, the Radix Scutellariae of the fire of alternative relieving cough and asthma famous medicine Semen Armeniacae Amarum, the kind clear part of the body cavity above the diaphragm housing the heart and lungs, the Fructus Trichosanthis of removing heat-phlegm, the wind heat of loosing, throat, the bullate Rhizoma Belamcandae of sterilization, Fructus Arctii, the Radix Angelicae Dahuricae are ministerial drug, assist monarch drug, strengthen the efficacy of a drug; Again phase modulation must and the heat clearing away YIN nourishing of usefulness partner Gypsum Fibrosum, the Rhizoma Anemarrhenae, the Herba Schizonepetae of being longer than the table wind of dispelling, the Radix Saposhnikoviae that drives endogenous wind, the Herba Menthae of heat radiation sore-throat relieving, the Rhizoma Phragmitis of kind clearing away lung-heat, the Pheretima that endogenous wind stopping is relievingd asthma are adjuvant drug, the collaborative the monarch and his subjects' a helping hand that helps; The Radix Platycodonis, conducting blood to flow downwards of sending up, the through focus of medicine carrying again with fiery Radix Cyathulae, the clearing away heat and promoting diuresis that fall inflammation, heal in external Talcum, have invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, nourishing the lung to arrest cough, the levelling famous medicine Radix Glycyrrhizae of being good at coordinating the actions of various ingredients in a prescription is a messenger drug, cooperates monarch, minister, adjuvant drug to put down and kills avian infectious laryngotracheitis virus and displace the malicious heresy of remnants external.So monarch of the present invention, minister, help, make prescription rigorous, the division of labor is clear and definite, and Each performs its own functions, and coordination linkage is played the medicine merit altogether.In addition, when clinical practice, increased by two foreign aid's medicines of saccharide and Vc again, supply is supported, diffusing virulence, has more strengthened eliminating pathogenic factor for supporting vital QI effect of the present invention.Therefore, originally bright have higher clinical cure rate than other related drugs.
The specific embodiment:
Following examples are in order to explanation the present invention.
Embodiment 1:
The medicine of control chicken infectious laryngotracheitis, the prescription composition is expressed as by weight:
Herba Ephedrae 5, Radix Isatidis 5, Folium Pyrrosiae 5, Radix Sophorae Tonkinensis 5, Rhizoma Dioscoreae Bulbiferae 5, Radix Stephaniae Cepharanthae 5, Bulbus Fritillariae Thunbergii 5, Semen Armeniacae Amarum 3, Radix Scutellariae 3, Fructus Trichosanthis 3, Rhizoma Belamcandae 3, Fructus Arctii 3, the Radix Angelicae Dahuricae 3, Gypsum Fibrosum 8, the Rhizoma Anemarrhenae 2, Herba Schizonepetae 2, Herba Menthae 2, Radix Saposhnikoviae 2, Rhizoma Phragmitis 2, Pheretima 2, Radix Glycyrrhizae 1, Radix Platycodonis 1, Radix Cyathulae 1, Talcum 3.
60 mesh sieves are dried, weigh, pulverized to said medicine, and stirring gets final product.
The inventor utilizes this prescription medicine to be used for clinical treatment, has obtained better curative effect, and concrete condition is as follows:
For the examination place: Gaocheng City, Hebei journey chicken house of going to the capital.
For trying the chicken group: 253 ages in days, the blue brown commodity in sea are for the laying hen group.
Chicken group quantity: 3000, because of immuning failure outburst chicken infectious laryngotracheitis, with group's house together.
Test group: 1500, use Drug therapy of the present invention.
Matched group: 1500, with Western medicine moroxydine, penicillin, streptomycin symptomatic treatment.
The test group step is as follows:
1. claim medicine: every chicken medication of test group 1g, nominal is got the above-mentioned Chinese medicine powder of 1500g and is poured in the cylinder.
2. soak: in cylinder, add boiling water 7.5kg, add a cover and soak stewing 30 minutes.
3. dosing: when treating that the medicine juice temperature is reduced to 20-25 ℃, add 0.75kg white sugar and 1.5gVc powder, stir evenly and get final product.
4. throw clothes: before the feeding, once drop into this medicinal liquid (containing medicinal residues) for the chicken group between the lights, appoint the free drink-service of chicken group.
5. course of treatment; Continuous use 3 days.
Matched group: select the Western medicine moroxydine for use for 1500 chickens, consumption is 0.02g/, altogether 30g; Benzylpenicillin, consumption are 50,000 units/only, shared 7,500 ten thousand units; Streptomycin sulfate, consumption are 200 milligrams/, and shared 300g pours above-mentioned three kinds of water medicine powders in the 7.5kg drinking-water into, stir the back throwing and obey, and appoint the free drink-service of chicken group.Continuous use 3 days.
Therapeutic outcome is listed in the table below: unit: only, %
The result shows: test group exceeds 10.47 percentage points than the cure rate of matched group.
Embodiment 2:
The medicine of control chicken infectious laryngotracheitis, the prescription composition is expressed as by weight:
Herba Ephedrae 12, Radix Isatidis 12, Folium Pyrrosiae 12, Radix Sophorae Tonkinensis 12, Rhizoma Dioscoreae Bulbiferae 12, Radix Stephaniae Cepharanthae 12, Bulbus Fritillariae Thunbergii 12, Semen Armeniacae Amarum 5, Radix Scutellariae 5, Fructus Trichosanthis 5, Rhizoma Belamcandae 5, Fructus Arctii 5, the Radix Angelicae Dahuricae 5, Gypsum Fibrosum 12, the Rhizoma Anemarrhenae 3, Herba Schizonepetae 4, Herba Menthae 4, Radix Saposhnikoviae 4, Rhizoma Phragmitis 4, Pheretima 4, Radix Glycyrrhizae 2, Radix Platycodonis 2, Radix Cyathulae 2, Talcum 5.80 mesh sieves are dried, pulverized to said medicine, and stirring gets final product.
The inventor has carried out clinical practice with this medicine, and the detailed results record is as follows:
For trying the place: Xingtai city Yang Zhuan province chicken house.
For trying the chicken group: 213 ages in days, assorted 579 commodity of star are for the laying hen group.
Chicken group quantity: 6000, because of improper ventilation brings out chicken infectious laryngotracheitis, with group's house together.
Test group: 3000, use Drug therapy of the present invention.
Matched group: 3000, with commercially available herbal medicine tetrahydro-isoquinolin treatment.
The test group step is as follows:
1. claim medicine: every chicken medication of test group 1.5g, nominal is got the above-mentioned Chinese medicine powder of 4500g and is poured in the cylinder.
2. soak: in cylinder, add boiling water 45kg, add a cover and soak stewing 50 minutes.
3. dosing: when treating that the medicine juice temperature is reduced to 20-25 ℃, add 4.5kg white sugar and 9gVc powder, stir evenly and get final product.
4. throw clothes: before the feeding, once drop into this medicinal liquid (containing medicinal residues) for the chicken group between the lights, appoint the free drink-service of chicken group.
5. course of treatment; Continuous use 5 days.
Matched group: take by weighing Chinese medicine tetrahydro-isoquinolin for animals for 3000 sick chickens, consumption 1.5g/ only is total to 4500g, before the dusk feeding, admixes feedstuff and once throws clothes, continuous use 5 days.
Therapeutic outcome is listed in the table below: unit: only, %
The result shows: test group exceeds 6.3 percentage points than the cure rate of matched group.
Claims (3)
1, a kind of medicine of preventing and treating chicken infectious laryngotracheitis is characterized in that the prescription composition is expressed as by weight:
Herba Ephedrae 5-15, Radix Isatidis 5-15, Folium Pyrrosiae 5-15, Radix Sophorae Tonkinensis 5-15, Rhizoma Dioscoreae Bulbiferae 5-15, Radix Stephaniae Cepharanthae 5-15, Bulbus Fritillariae Thunbergii 5-15, Semen Armeniacae Amarum 3-8, Radix Scutellariae 3-8, Fructus Trichosanthis 3-8, Rhizoma Belamcandae 3-8, Fructus Arctii 3-8, Radix Angelicae Dahuricae 3-8, Gypsum Fibrosum 8-20, Rhizoma Anemarrhenae 2-5, Herba Schizonepetae 2-5, Herba Menthae 2-5, Radix Saposhnikoviae 2-5, Rhizoma Phragmitis 2-5, Pheretima 2-5, Radix Glycyrrhizae 1-3, Radix Platycodonis 1-3, Radix Cyathulae 1-3, Talcum 3-6.
2,, it is characterized in that the prescription composition is expressed as by weight by the medicine of the described treatment chicken infectious laryngotracheitis of claim 1:
Herba Ephedrae 5, Radix Isatidis 5, Folium Pyrrosiae 5, Radix Sophorae Tonkinensis 5, Rhizoma Dioscoreae Bulbiferae 5, Radix Stephaniae Cepharanthae 5, Bulbus Fritillariae Thunbergii 5, Semen Armeniacae Amarum 3, Radix Scutellariae 3, Fructus Trichosanthis 3, Rhizoma Belamcandae 3, Fructus Arctii 3, the Radix Angelicae Dahuricae 3, Gypsum Fibrosum 8, the Rhizoma Anemarrhenae 2, Herba Schizonepetae 2, Herba Menthae 2, Radix Saposhnikoviae 2, Rhizoma Phragmitis 2, Pheretima 2, Radix Glycyrrhizae 1, Radix Platycodonis 1, Radix Cyathulae 1, Talcum 3.
3,, it is characterized in that the prescription composition is expressed as by weight by the medicine of the described treatment chicken infectious laryngotracheitis of claim 1:
Herba Ephedrae 12, Radix Isatidis 12, Folium Pyrrosiae 12, Radix Sophorae Tonkinensis 12, Rhizoma Dioscoreae Bulbiferae 12, Radix Stephaniae Cepharanthae 12, Bulbus Fritillariae Thunbergii 12, Semen Armeniacae Amarum 5, Radix Scutellariae 5, Fructus Trichosanthis 5, Rhizoma Belamcandae 5, Fructus Arctii 5, the Radix Angelicae Dahuricae 5, Gypsum Fibrosum 12, the Rhizoma Anemarrhenae 3, Herba Schizonepetae 4, Herba Menthae 4, Radix Saposhnikoviae 4, Rhizoma Phragmitis 4, Pheretima 4, Radix Glycyrrhizae 2, Radix Platycodonis 2, Radix Cyathulae 2, Talcum 5.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101342327B (en) * | 2008-08-19 | 2010-12-01 | 宫兆荣 | Traditional Chinese medicine composing prescription for treating children's upper respiratory tract infection |
| CN102357158A (en) * | 2011-10-24 | 2012-02-22 | 中国农业科学院兰州畜牧与兽药研究所 | Medicament for preventing and curing avian infectious laryngotracheitis and preparation method thereof |
| CN102488828A (en) * | 2011-12-29 | 2012-06-13 | 重庆市畜牧科学院 | Chinese medicinal composition for treating infectious bronchitis and its preparation method |
| CN103055090A (en) * | 2012-12-04 | 2013-04-24 | 青岛绿曼生物工程有限公司 | Pure Chinese medicinal composition for treating fowl cholera and preparation method of pure Chinese medicinal composition |
| CN103860643A (en) * | 2014-03-19 | 2014-06-18 | 湖州天健兽药有限公司 | Drug for treating infectious laryngotracheitis |
| CN105727109A (en) * | 2016-04-07 | 2016-07-06 | 张传津 | Pure Chinese herb powder for preventing and treating infectious bronchitis and preparation method thereof |
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| CN102293875B (en) * | 2011-08-30 | 2013-03-27 | 广西北斗星动物保健品有限公司 | Compound glabrous sarcandra herb, and preparation methods for granular preparation and oral liquid of compound glabrous sarcandra herb |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101342327B (en) * | 2008-08-19 | 2010-12-01 | 宫兆荣 | Traditional Chinese medicine composing prescription for treating children's upper respiratory tract infection |
| CN102357158A (en) * | 2011-10-24 | 2012-02-22 | 中国农业科学院兰州畜牧与兽药研究所 | Medicament for preventing and curing avian infectious laryngotracheitis and preparation method thereof |
| CN102488828A (en) * | 2011-12-29 | 2012-06-13 | 重庆市畜牧科学院 | Chinese medicinal composition for treating infectious bronchitis and its preparation method |
| CN103055090A (en) * | 2012-12-04 | 2013-04-24 | 青岛绿曼生物工程有限公司 | Pure Chinese medicinal composition for treating fowl cholera and preparation method of pure Chinese medicinal composition |
| CN103860643A (en) * | 2014-03-19 | 2014-06-18 | 湖州天健兽药有限公司 | Drug for treating infectious laryngotracheitis |
| CN105727109A (en) * | 2016-04-07 | 2016-07-06 | 张传津 | Pure Chinese herb powder for preventing and treating infectious bronchitis and preparation method thereof |
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| CN100512860C (en) | 2009-07-15 |
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Assignee: Zhongshan Kelang poultry Co.,Ltd. Assignor: HEIBEI AGRICULTURAL UNIVERSITY Contract record no.: 2010440000890 Denomination of invention: Medicine for preventing and controlling chicken infectious laryngotracheitis Granted publication date: 20090715 License type: Exclusive License Open date: 20070124 Record date: 20100706 |
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