CN1879857A - Medicinal powder for treating mammary gland disease - Google Patents
Medicinal powder for treating mammary gland disease Download PDFInfo
- Publication number
- CN1879857A CN1879857A CNA2006100118545A CN200610011854A CN1879857A CN 1879857 A CN1879857 A CN 1879857A CN A2006100118545 A CNA2006100118545 A CN A2006100118545A CN 200610011854 A CN200610011854 A CN 200610011854A CN 1879857 A CN1879857 A CN 1879857A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- herba
- rhizoma
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a pharmaceutical composition for treating mammary gland diseases and process for preparation, wherein the raw materials include root of red rooted saliva, bulb of edible tulip, Chinese angelica root, Clematis chinensis, curcuma aromatica, sarcodactylis swinple, burred tuber, zedoary, Bupleurum root, centipede, buthus martensi karsch, apiary, Chinese honeylocust spine, black nightshade, snakegourd, rhubarb horsetails, fritillary, Oldenlandis, barbat skullcap, Chinese sage, phoenix-tail fern, selfheal, European verbena, giant knotweed rhizome, seed of cowherb and licorice powder.
Description
Technical field
The invention discloses a kind of medicine and preparation method for the treatment of mastopathy, is the Chinese medicine preparation of feedstock production with Chinese medicine specifically, belongs to the field of Chinese medicines.
Background technology
At present, mastotic sickness rate is year by year the trend that rises, wherein malignant tumor of breast---and the sickness rate of breast carcinoma is just with annual 2.4% speed increase, to leap to the first place of women's malignant tumor, account for 1/4 of all malignant tumor of women, become the No.1 killer who threatens women's life.At present the of the right age women of the U.S. to generally investigate the breast carcinoma recall rate be 1/8, China's breast carcinoma sickness rate also sharply rises, age of onset is rejuvenation day by day, age bracket occurred frequently is 30-49 year, the U.S. is 10 years in advance.Chinese women 30-49 year breast carcinoma sickness rate 21.4%, the U.S. is 7.3%; But American Women breast carcinoma sickness rate is 24% after 70 years old, and Chinese women only are 4.8%.This investigation shows that the rejuvenation of Chinese women's breast carcinoma age of onset is very serious, and expert call: young women more should be watched out for breast carcinoma.Therefore, modern female more should be paid attention to udder health, carry out women's breast health promotion in all one's life, regularly carry out the inspection of mammary gland, accomplish " discovery early, diagnosis morning, early treatment ", adjust endocrine regulation timely and effectively, the control cystic hyperplasia of breast, reduce the sickness rate of breast carcinoma, keep the breast profile complete, plentiful, vigorous and graceful.
The traditional Chinese medical science think the mastopathy origin cause of formation have following several: depressed emotion, anxiety and rage, expectorant is turbid to be condensed, the liver losing its smoothly moving state makes the liver-yang hyperactivity stagnation of QI then, accumulates in expectorant is turbid, stagnation of QI expectorant is turbid capable with meridians, because feelings will internal injury, liver temper is contrary, give birth in expectorant is turbid, the turbid knot of stagnation of QI expectorant is poly-not to loose, and QI and blood is stopped up stagnant for it, and blood forms the stasis of blood with the stagnation of QI, the stasis of blood of accumulating in the course of time the poison that congeals into, the chronic knot of stagnation of QI phlegm-turbidity and blood stasis poison three forms primary disease.
At present, though the medicine of treatment mastopathy is a lot, or does not have compellent clinical data and model case, curative effect makes us doubting, or lacks pharmacodynamic experiment data and safety research, and toxicity is unknown.Traditional therapy is also nothing more than attacking the pathogens first and then tonifying or tonifying first and then eliminating the pathogen, pain relieving by force, and symptomatic treatment in acute condition, rules such as relieving the primary symptom in a chronic case are difficult to tackle the problem at its root.
Summary of the invention
Purpose of the present invention is exactly the problem at above-mentioned existence, need not perform the operation and provide a kind of, has resolving phlegm and softening hard masses, blood circulation promoting and blood stasis dispelling, counteracting toxic substances is anticancer, holder skin ulcer granulation promoting, and the repercussive toxin expelling is applicable to the treatment of all kinds of mastopathy, safe and simple quick, have no side effect, and the high Chinese medicine preparation of cure rate.
This prescription is to pacify rock according to secret prescription handed down in the family from generation to generation by having 37 years empirical traditional Chinese medical science chief physicians of tcm clinical practice, excavate the traditional Chinese medical science and enrich clinical experience, in conjunction with modern pharmacological research, test drawing in a large number, each amounts of components all has better curative effect in the following weight parts scope.
Radix Salviae Miltiorrhizae 10-30 part, Pseudobulbus Cremastrae Seu Pleiones 20-40 part, Radix Angelicae Sinensis 10-30 part, Radix Clematidis 10-20 part, Radix Curcumae 10-20 part, Fructus Citri Sarcodactylis 10-20 part, rhizoma sparganic 10-30 part, Rhizoma Curcumae 10-30 part, Radix Bupleuri 10-30 part, Scolopendra 5-15 part, Scorpio 5-15 part, Nidus Vespae 10-30 part, Spina Gleditsiae 10-20 part, Radix Semiaquilegiae 10-20 part, Fructus Trichosanthis 20-40 part, Radix Et Rhizoma Rhei 10-30 part, Bulbus Fritillariae Uninbracteatae 10-30 part, tongue snakeweed 20-40 part, Herba Scutellariae Barbatae 20-40 part, Herba Salviae Chinensis 20-40 part, Herba Pteridis Multifidae 20-40 part, Spica Prunellae 20-40 part, Herba Verbenae 20-40 part, Rhizoma Polygoni Cuspidati 10-30 part, the king does not stay 10-30 part, Radix Glycyrrhizae 5-15 part.
Be preferably: 20 parts of Radix Salviae Miltiorrhizaes, 30 parts of Pseudobulbus Cremastrae Seu Pleioness, 20 parts of Radix Angelicae Sinensis, 15 parts of Radix Clematidis, 15 parts of Radix Curcumaes, 15 parts of Fructus Citri Sarcodactylis, 20 parts of rhizoma sparganic, 20 parts of Rhizoma Curcumae, 20 parts of Radix Bupleuri, 10 parts of Scolopendras, 10 parts of Scorpios, 20 parts in Nidus Vespae, 15 parts of Spina Gleditsiae, 15 parts of Radix Semiaquilegiaes, 30 parts of Fructus Trichosanthis, 20 parts of Radix Et Rhizoma Rhei, 20 parts of Bulbus Fritillariae Uninbracteataes, 30 parts of tongue snakeweed, 30 parts of Herba Scutellariae Barbataes, 30 parts of Herba Pteridis Multifidaes, 30 parts of Herba Salviae Chinensiss, 30 parts of hays, 30 parts of Herba Verbenae, 20 parts of Rhizoma Polygoni Cuspidati, king do not stay 10 parts of 20 parts, Radix Glycyrrhizae.
Radix Salviae Miltiorrhizae wherein: contain Tanshinone I, IIA, IIB, iso tanshinone I, II, iso tanshinone, Methyl tanshinoate, miltirone, salviol in addition, still contain protocatechualdehyde, protocatechuic acid, β lactic acid, vitamin E etc.Zoopery shows that Radix Salviae Miltiorrhizae can obviously prolong the time-to-live of ehrlich carcinoma mice, and sodium tanshinone IIA sulfate can improve the effect of the anti-ehrlich carcinoma ascitic type of hydroxy camptothecin (ECA).Radix Salviae Miltiorrhizae does not have mass formed by blood stasis to the high fibrin in the blood coagulation one fibrinolytic one platelet system disorder of tumor host Accommodation is arranged, mice S180 oncocyte there is cytotoxicity, it is synthetic to suppress DNA, acts on the S phase of tumor cell proliferation in the cycle, i.e. DNA two multiplications are grown the phase.Malignant tumor patient is used the anti-tumor activity that has improved chemotherapeutics behind the Radix Salviae Miltiorrhizae, and Radix Salviae Miltiorrhizae, urokinase can improve the anti-tumor activity of cyclophosphamide, and Radix Salviae Miltiorrhizae adds ring phosphorus and is better than urokinase at the antitumous effect of amide and adds cycli phosphate amine; Pseudobulbus Cremastrae Seu Pleiones: sweet, little suffering, cold.Return liver, spleen channel.This product is cold with removing summer-heat, and the hot carbuncle that looses has heat-clearing and toxic substances removing, the merit of eliminating carbuncle eliminating stagnation.Heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation are used for cards such as carbuncle carbuncle on the back, the swollen malignant boil of furuncle, scrofula tuberculosis; Radix Angelicae Sinensis: sweet, bitter, hot, warm.Function is for enriching blood, invigorating blood circulation, and regulating menstruation is moisturized, laxation.Cure mainly menoxenia, blood deficiency or blood stasis amenorrhea, the dysmenorrhoea metrorrhagia, ulcer sore pain, wind is executed arthralgia pain, and blood deficiency such as just closes at disease, is gynecological's key medicine; Radix Clematidis: hot, salty, warm, go into 12 warps.Wind-damp dispelling, the meridian dredging, it act as analgesia.The vinegar immersion of this product has certain emollescence to fish bony spur; Radix Curcumae: hot, bitter, cold.Go into the heart, liver, lung meridian.Soothing liver-QI for relieving depression, pain relieving.Cure mainly two side of body overflows, breast abdomen pain, dysmenorrhea; Fructus Citri Sarcodactylis: hot, bitter, tepor.Go into the lung spleen channel.Regulate the flow of vital energy, soothing liver-QI and in.It is strongly fragrant to cure mainly the liver gastric qi, the fullness in the chest stagnation of QI; Rhizoma sparganic: bitter, hot, flat.Return liver, spleen channel.Removing blood stasis, the amenorrhea that Zhu Zhi lumps in the chest and abdomen and qi depression to blood stasis cause.Promoting the circulation of QI to relieve pain; Rhizoma Curcumae: bitter, hot, warm.Return liver, spleen channel.Promoting the circulation of QI to relieve pain, removing blood stasis, women's amenorrhea, phlegm-damp congestion condenses and forms De mass in the abdomen addiction piece; Radix Bupleuri: bitter in the mouth, cold nature.Reducing fever by reconciliation is arranged, dispersing the stagnated live-QI to relieve the stagnation of QI, the function of ascending spleen-QI.Saikoside has central nerve inhibition effect and effects such as tangible antiinflammatory and prevention of digestive tract ulcers such as analgesia, calmness, analgesic, antitussive; Scolopendra: suffering, temperature.Poisonous.Return Liver Channel.The endogenous wind stopping relieving convulsion, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain; Scorpio: acrid in the mouth, but wind-phlegm poison, suppressing the hyperactive liver to relieve the wind syndrome, the meridians dredging of expellingging wind and relieving convulsion, town's cancer pain relieving, dispersing pathogen accumulation; Nidus Vespae: property is flat, and bitter in the mouth is salty little sweet, goes into liver, kidney, stomach three warps.The counteracting toxic substances that dispels the wind, the swollen pain relieving of loosing; Spina Gleditsiae: suffering, temperature.Return liver, stomach warp, the evacuation of pus of drawing out pus by applying a plaster to the affected part, promoting blood circulation and detumescence; Radix Semiaquilegiae: heat-clearing and toxic substances removing, reducing swelling and alleviating pain, diuresis; Fructus Trichosanthis: phlegm-heat cough, lung productive cough blood, uncomfortable in chest, disappear and rush down and constipation; Radix Et Rhizoma Rhei: bitter in the mouth, cold in nature.Return stomach, spleen, large intestine, liver, pericardium channel.Purging heat to relax the bowels, removing toxicity for eliminating carbuncles, clots absorbing stimulates the menstrual flow, removing damp-heat, cooling blood for hemostasis; Bulbus Fritillariae Uninbracteatae: be the bulb of Liliaceae herbaceos perennial, bitter in the mouth, sweet, cold nature.Main component contains biological alkali, is mainly loose shellfish alkali.Main effect is moistening the lung and resolving phlegm, eliminating stagnation heat extraction; Tongue snakeweed: contain oleanolic acid (oleanolic acid), right-coumaric acid (p-coumaric acid), stigmasterol, cupreol-D-glycoside, hentriacontane.Cool in nature, sweet in the mouth, light.Heat-clearing and toxic substances removing, diuresis of blood circulation promoting.Be used for tumor etc.; Herba Scutellariae Barbatae: suffering, flat.GUIXIN, small intestinal, lung meridian.Inducing diuresis to remove edema, heat-clearing and toxic substances removing.Be used for extensive abdominal edema, face foot edema, carbuncle furuncle etc.; Herba Salviae Chinensis: bitter in the mouth, suffering, cool in nature.Heat-clearing and toxic substances removing is arranged, functions such as blood circulation promoting regulates qi pain relieving.Be used for acute, chronic hepatitis, gastral cavity side of body distending pain, damp-heat vaginal discharge, mastitis, furuncle and phyma; Herba Pteridis Multifidae: lightly seasoned little hardship, cold in nature.Go into kidney, stomach two warps.Clearing away heat-damp and promoting diuresis, cooling blood for hemostasis, subduing swelling and detoxicating.Control intestinal cancer, pulmonary carcinoma, bladder cancer, gynecologic malignant tumor; Spica Prunellae: bitter in the mouth, suffering, cold.Cure mainly cold and heat, scrofula, scrofula, head sore, broken note of the ancient Chinese, the wart stagnation of QI that looses, swelling of the feet arthralgia chiefly caused by damp pathogen; Herba Verbenae: hardship, cold.Return liver, spleen channel.Promoting blood circulation to remove blood stasis, preventing the attack (or recurrence) of malaria, detoxifcation, inducing diuresis to remove edema.Yong the Yu lumps in the chest and abdomen, amenorrhea dysmenorrhea, malaria, sore throat, carbuncle, edema, pyretic stranguria; Rhizoma Polygoni Cuspidati: little hardship is slightly cold.Return liver, gallbladder, lung meridian.Expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.Be used for arthralgia, jaundice due to damp-heat, amenorrhea, { note of the ancient Chinese } abdominal mass, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus, cough with copious phlegm; The king does not stay and has another name called: grass, Fructus Hordei Vulgaris cattle, rabbit grass, Meccah dish, king bull nature and flavor are irritated in the road, and hardship is flat.Return liver, stomach warp.Promoting blood circulation to restore menstrual flow, the stimulating milk secretion detumescence.Be used for agalactia, amenorrhea, dysmenorrhea, acute mastitis swells and ache.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.Invigorating the spleen and replenishing QI is arranged, the merit of heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription.
All medicines share has soothing the liver dissipating depression of QI, resolving depression detumescence, the kidney tonifying of regulating the flow of vital energy, hard masses softening and resolving, the removing dampness of eliminating the phlegm, promoting blood circulation by regulating nutrient QI, invigorating the spleen and benefiting QI, eliminate stagnation and dissolve phlegm, the blood stasis removing that stimulates the menstrual flow, clearing away heat and cooling blood, detoxifcation is dried, dispersing cold for relieving pain, and the clots absorbing collateral dredging, the kidney invigorating is loose hard, the turbid kidney tonifying that disappears, counteracting toxic substances is eliminating evil, holder skin ulcer granulation promoting, right supporting anticancer, the detoxicating toxin expelling is let out heart-fire clearly, compensate qi and blood and reason taste, the easypro network that stimulates the menstrual flow, heat clearing away is warded off dirty, invigorating striae of the skin, the effect of strengthening vital QI to eliminate pathogenic factors.Attack and mend synchronously, amount GSMC is big.
The inventor has strengthened the stronger Chinese medicine of antitumaous effect in line with " right supporting anticancer ", has increased strengthening the body resistance simultaneously, and the medicine of the immunity of organism effect that is significantly improved by clinical observation, has better therapeutic effect, with the chemotherapy group contrast, is better than the chemotherapy matched group.From life quality and life cycle, be significantly improved than chemotherapy group.
Medicine of the present invention has the following advantages:
1. each component of medicine of the present invention all meets Pharmacopoeia of the People's Republic of China regulation, has the toxin expelling of invigorating blood circulation, hard masses softening and resolving, promoting the circulation of QI to relieve pain, the effect of antiinflammatory, detumescence, repercussive.Be applicable to cyclomastopathy, mastitis, mammary gland fibroma, mammary gland precancerous lesion, breast carcinoma, pointed strong, short treating period, the characteristics that cure rate is high;
2. taking convenience, safety;
3. curative effect is reliable, side effect is little;
4. the medicine of respectively distinguishing the flavor of source is easy to get, and is easy to promote;
5. production technology is simple, and is cheap.
This composition of medicine also can be made tablet, pill, powder, electuary, unguentum, capsule, oral liquid.
The present invention is described in further detail below in conjunction with instantiation that the inventor provides.
The specific embodiment
Embodiment 1
Take by weighing each raw material according to following weight parts
10 parts of Radix Salviae Miltiorrhizaes, 20 parts of Pseudobulbus Cremastrae Seu Pleioness, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Clematidis, 10 parts of Radix Curcumaes, 10 parts of Fructus Citri Sarcodactylis, 10 parts of rhizoma sparganic, 10 parts of Rhizoma Curcumae, 10 parts of Radix Bupleuri, 5 parts of Scolopendras, 5 parts of Scorpios, 10 parts in Nidus Vespae, 10 parts of Spina Gleditsiae, 10 parts of Radix Semiaquilegiaes, 20 parts of Fructus Trichosanthis, 10 parts of Radix Et Rhizoma Rhei, 10 parts of Bulbus Fritillariae Uninbracteataes, 20 parts of tongue snakeweed, 20 parts of Herba Scutellariae Barbataes, 20 parts of Herba Salviae Chinensiss, 20 parts of Herba Pteridis Multifidaes, 20 parts of Spica Prunellaes, 20 parts of Herba Verbenae, 10 parts of Rhizoma Polygoni Cuspidati, king do not stay 5 parts of 10 parts, Radix Glycyrrhizae.
Manufacture method: Radix Salviae Miltiorrhizae, Pseudobulbus Cremastrae Seu Pleiones, Radix Angelicae Sinensis, Radix Clematidis, Radix Curcumae, Fructus Citri Sarcodactylis, rhizoma sparganic, Rhizoma Curcumae, Radix Bupleuri, Scolopendra, Scorpio, Nidus Vespae, Spina Gleditsiae, Radix Semiaquilegiae, Fructus Trichosanthis, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, tongue snakeweed, Herba Scutellariae Barbatae, Herba Salviae Chinensis, Herba Pteridis Multifidae, Spica Prunellae, Herba Verbenae, Rhizoma Polygoni Cuspidati, Wang Buliu, Radix Glycyrrhizae pulverize separately are become fine powder, mix well after crossing 120 mesh sieves, routine is made powder, packages spare after the sterilization.
[usage and dosage] every day twice, each 15 grams, be a course of treatment January, three months is a big course of treatment.
[taboo] forbids when property of drug changes, contraindication in pregnancy.
[storage] is airtight, puts shady and cool place.
Embodiment 2
Take by weighing each component raw material according to following weight parts:
30 parts of Radix Salviae Miltiorrhizaes, 40 parts of Pseudobulbus Cremastrae Seu Pleioness, 30 parts of Radix Angelicae Sinensis, 20 parts of Radix Clematidis, 20 parts of Radix Curcumaes, 20 parts of Fructus Citri Sarcodactylis, 30 parts of rhizoma sparganic, 30 parts of Rhizoma Curcumae, 30 parts of Radix Bupleuri, 15 parts of Scolopendras, 15 parts of Scorpios, 30 parts in Nidus Vespae, 20 parts of Spina Gleditsiae, 20 parts of Radix Semiaquilegiaes, 40 parts of Fructus Trichosanthis, 30 parts of Radix Et Rhizoma Rhei, 30 parts of Bulbus Fritillariae Uninbracteataes, 40 parts of tongue snakeweed, 40 parts of Herba Scutellariae Barbataes, 40 parts of Herba Salviae Chinensiss, 40 parts of Herba Pteridis Multifidaes, 40 parts of Spica Prunellaes, 40 parts of Herba Verbenae, 30 parts of Rhizoma Polygoni Cuspidati, king do not stay 15 parts of 30 parts, Radix Glycyrrhizae.
Manufacture method, usage, consumption, taboo, storage are with embodiment 1.
Embodiment 3
Take by weighing each component raw material according to following weight parts:
20 parts of Radix Salviae Miltiorrhizaes, 30 parts of Pseudobulbus Cremastrae Seu Pleioness, 20 parts of Radix Angelicae Sinensis, 15 parts of Radix Clematidis, 15 parts of Radix Curcumaes, 15 parts of Fructus Citri Sarcodactylis, 20 parts of rhizoma sparganic, 20 parts of Rhizoma Curcumae, 20 parts of Radix Bupleuri, 10 parts of Scolopendras, 10 parts of Scorpios, 20 parts in Nidus Vespae, 15 parts of Spina Gleditsiae, 15 parts of Radix Semiaquilegiaes, 30 parts of Fructus Trichosanthis, 20 parts of Radix Et Rhizoma Rhei, 20 parts of Bulbus Fritillariae Uninbracteataes, 30 parts of tongue snakeweed, 30 parts of Herba Scutellariae Barbataes, 30 parts of Herba Pteridis Multifidaes, 30 parts of Herba Salviae Chinensiss, 30 parts of hays, 30 parts of Herba Verbenae, 20 parts of Rhizoma Polygoni Cuspidati, king do not stay 10 parts of 20 parts, Radix Glycyrrhizae.
Manufacture method, usage, consumption, taboo, storage are with embodiment 1.
In order to verify the good effect of medicine of the present invention, the inventor has carried out a large amount of experiments, now selects the part clinical experiment report as follows, and the commodity of medicinal powder for treating mammary gland disease red kind lactogenesis three by name dissipates.
Test 1
Red kind lactogenesis three dissipates and treats cyclomastopathy 348 routine clinical observation on the therapeutic effect summaries
Red kind lactogenesis three dissipate system's treatment cyclomastopathy through proved recipe, all kinds of cyclomastopathy 348 examples are treated with this medicine by our three tame hospitals, obtained curative effect preferably, now 348 red kind lactogenesis three dissipation treatment groups of example and 156 routine western medicine matched group clinical observation result have been summarized as follows.
Clinical data
348 routine cyclomastopathy patients clarify a diagnosis by the diagnostic criteria of national specialized conference cyclomastopathy, all take red kind lactogenesis three dissipate more than one month as the object of observation.In the 348 routine treatment groups, minimum 18 years old of age, maximum 65 years old.
The cyclomastopathy classification
(1) simple breast epithelium hypertrophy (mastalgia): belonging to the mammary gland physiological and change, is that cyclomastopathy changes in early days, just cyclomastopathy.
(2) adenosis of breast: lobules of mammary gland tubule, tip conduit and connective tissue hypertrophy in various degree.
(3) cyst breast epithelium hypertrophy disease (cystic disease of breast): it is principal character that lobule, conduit and the expansion of tip duct height form with the cyst, companion's dysplasia, and the someone thinks precancerous lesion.
Criterion of therapeutical effect
Alleviate fully: visible lump complete obiteration.
Part is alleviated: the product of focus maximum gauge and maximum perpendicular diameter thereof dwindles more than 50%, and other focuses do not have increase.
Stable: focus two footpath products dwindle less than 50%, increase to be no more than 25%.
Invalid: (deterioration) focus two footpath products increase above more than 25%.
Therapeutic Method
The treatment group is taken red kind lactogenesis three dissipations, every day twice, and each 15 grams, be a course of treatment January, three months is a big course of treatment.Generally took three months.Matched group is taken amcinonide, takes by operation instruction.
Therapeutic outcome
(1) treatment group 348 examples and matched group 156 routine observation of curative effect.See Table 1
Table 1 treatment group and matched group curative effect are relatively
| Classification | The example number | Cure fully (routine %) | Part is cured (routine %) | Stable (routine %) | Invalid (routine %) | Effective percentage (routine %) | ||||||
| (1) | (2) | (1) | (2) | (1) | (2) | (1) | (2) | (1) | (2) | (1) | (2) | |
| Mastalgia adenosis of breast cystic disease of breast (breast epithelium hypertrophy) amounts to | 148 112 88 348 | 85 40 31 156 | 79 51 32 162 | 10 8 3 21 | 49 47 36 132 | 18 6 6 30 | 17 12 18 47 | 22 12 12 46 | 3 2 2 7 | 35 12 10 57 | 98 98 97 97.6 | 59 70 67 65. |
Annotate: on behalf of treatment group (2), (1) represent matched group
Table 1 explanation, red kind lactogenesis three dissipation treatment groups all have certain curative effect to all kinds of cyclomastopathy, and total effective rate is 97.6%, and western medicine group total effective rate is 65%.
The improvement situation of table 2 clinical symptoms
| Symptom | Distending pain of the breast | Lump in breast | Menoxenia | Dysmenorrhea | Constipation | Leucorrhoea grow in quantity has abnormal flavour | Vexed bitter taste | Insomnia is depressed | Two side of body distensions |
| Treatment back effective percentage (%) before the treatment | 342 5 98.53 | 340 15 95.58 | 275 4 98.54 | 230 5 97.82 | 165 1 99.39 | 320 3 99.06 | 256 2 99.21 | 287 1 99.65 | 305 1 99.67 |
The conventional treatments of table 3 cyclomastopathy and comparison:
Test 2
Red kind lactogenesis three dissipates and treats the clinical observation on the therapeutic effect brief summary of 268 routine mastitis
Red kind lactogenesis three dissipates system through proved recipe, and we have carried out clinical observation to the mastitis patient, now are reported as follows:
Clinical data
Case is selected: all mastitis patients who makes a definite diagnosis, obey red kind lactogenesis three dissipation 3-15 days persons, and all classify the object of observation as.
General qualifications and record of service material: in 268 examples of observation, oldest 35 years old, minimum 18 years old.
Criterion of therapeutical effect
Alleviate fully: visible inflammation complete obiteration.
Part is alleviated: the product of focus maximum gauge and maximum perpendicular diameter thereof dwindles more than 50%, and other focuses do not have increase.
Stable: focus two footpath products dwindle less than 50%, increase to be no more than 25%.
Invalid: (deterioration) focus two footpath products increase above more than 25%.
Therapeutic outcome
(1) 268 routine clinical treatment curative effect statistics as a result sees Table 1
Table 1 treatment group and matched group curative effect are relatively
| Classification | The example number | Cure fully (routine %) | Part is cured (routine %) | Stable (routine %) | Invalid (routine %) | Effective percentage (routine %) | ||||||
| (1) | (2) | (1) | (2) | (1) | (2) | (1) | (2) | (1) | (2) | (1) | (2) | |
| Deposit impatient property mastitis mammary gland conduit fistula tuberculosis of breast of acute mastitis amounts to | 134 55 25 54 268 | 90 42 18 48 198 | 130 51 18 27 226 | 61 31 7 13 113 | 4 47 5 16 72 | 16 6 5 9 36 | 0 0 1 11 12 | 10 2 1 13 26 | 0 0 1 0 1 | 3 3 5 9 20 | 100 100 96 100 99 | 96 93 72 81 89 |
Table 1 prompting: 268 routine therapeutic outcomes, total effective rate 99%.
(2) red kind lactogenesis three dissipations see Table 2 to the improvement situation of cancer clinical symptoms
The improvement situation of table 2 clinical symptoms
| Symptom | Distending pain of the breast | Lump in breast | Menoxenia | Dysmenorrhea | Constipation | Leucorrhoea grow in quantity, abnormal flavour is arranged | Vexed bitter taste | Insomnia is depressed | Two side of body distensions |
| Treatment back effective percentage (%) before the treatment | 268 5 97.38 | 268 22 91.79 | 158 5 96.83 | 225 1 99.55 | 158 1 99.36 | 222 6 97.29 | 203 3 98.52 | 116 3 97.41 | 233 2 99.14 |
Test 3
Red kind lactogenesis three dissipates and treats mammary gland fibroma 285 routine clinical observation on the therapeutic effect brief summaries
The general non-evident sympton of mammary gland fibroma, no pain and tenderness, thereby the discovery of tumor mostly is accidental, pilosity is born in 20-25 year young women, and the rate of cancerating is 1/100, becomes lobular carcinoma, comedocarcinoma and sarcoma.The hebephrenictype mammary gland fibroma should not be taked excision.
Physical data
285 examples are organized in red kind lactogenesis three dissipation treatments, 18 years old of age minimum, maximum 30 years old.
Criterion of therapeutical effect
Alleviate fully: visible fibroma complete obiteration.
Part is alleviated: the product of focus maximum gauge and maximum perpendicular diameter thereof dwindles more than 50%, and other focuses do not have increase.
Stable: focus two footpath products dwindle less than 50%, increase to be no more than 25%.
Invalid: (deterioration) focus two footpath products increase above more than 25%.
Therapeutic Method
The treatment group is taken red kind lactogenesis three dissipations, every day twice, and each 15 grams, be a course of treatment January, three months is a big course of treatment, generally takes three months.Matched group two groups of therapeutic scheme 3 courses of treatment all is equipped with Supporting Therapy routinely.
Table 1 treatment group and matched group curative effect are relatively
| Classification | The example number | Cure fully (routine %) | Part is cured (routine %) | Stable (routine %) | Invalid (routine %) | Effective percentage (routine %) | ||||||
| (1) | (2) | (1) | (2) | (1) | (2) | (1) | (2) | (1) | (2) | (1) | (2) | |
| Mammary gland fibroma amounts to | 285 285 | 103 103 | 205 205 | 36 36 | 34 34 | 27 27 | 42 42 | 20 20 | 4 4 | 20 20 | 98 98 | 80 80 |
The improvement situation of table 2 clinical symptoms
| Symptom | Distending pain of the breast | Lump in breast | Menoxenia | Dysmenorrhea | Constipation | Leucorrhoea grow in quantity, abnormal flavour is arranged | Vexed bitter taste | Insomnia is depressed | Two side of body distensions |
| Treatment back effective percentage (%) before the treatment | 255 4 98.43 | 285 24 91.57 | 163 8 95.09 | 212 4 98.11 | 132 3 97.72 | 233 7 96.99 | 211 5 97.63 | 135 4 97.03 | 256 4 98.43 |
Test 4
Red kind lactogenesis three dissipates and treats breast carcinoma of early stage 35 routine clinical observation on the therapeutic effect brief summaries
Breast carcinoma is the common a kind of malignant tumor of women.Though the definite cause of disease of relevant breast carcinoma is also failed clear and definite fully, it is generally acknowledged with factors such as ovarian function, inherited genetic factors, marriage and childbirth and sucklings has substantial connection.Therefore breast carcinoma mainly betides the later adult women of adolescence, accounts for whole patients' 75% for sending out the age well in 35 ~ 55 years old.A large amount of clinical datas has illustrated this point.
Criterion of therapeutical effect
Alleviate fully: visible carcinoma complete obiteration.
Part is alleviated: the product of focus maximum gauge and maximum perpendicular diameter thereof dwindles more than 50%, and other focuses do not have increase.
Stable: focus two footpath products dwindle less than 50%, increase to be no more than 25%.
Invalid: (deterioration) focus two footpath products increase above more than 25%.
Therapeutic outcome
(1) treatment group 35 examples relatively see Table I with matched group 28 routine curative effects.
Table 1 treatment group observation of curative effect table
| Classification | The example number | Alleviate fully (routine %) | Part is alleviated (routine %) | Stable (routine %) | Invalid (routine %) | Effective percentage (routine %) | ||||||
| (1) | (2) | (1) | (2) | (1) | (2) | (1) | (2) | (1) | (2) | (1) | (2) | |
| Breast carcinoma of early stage amounts to | 35 35 | 28 28 | 12 18 | 2 2 | 6 12 | 2 1 | 4 4 | 3 5 | 13 0 | 21 20 | 63 63 | 25 25 |
Annotate: (1) represents the treatment group, and (2) represent matched group.
Table 1 prompting, red kind lactogenesis three dissipates breast carcinoma of early stage is had certain curative effect, and effective percentage is 63%, and the effective percentage of western medicine group is 25%.
The improvement situation of table 2 clinical symptoms
| Symptom | Distending pain of the breast | Lump in breast | Menoxenia | Dysmenorrhea | Constipation | Leucorrhoea grow in quantity, abnormal flavour is arranged | Vexed bitter taste | Insomnia is depressed | Two side of body distensions |
| Treatment back effective percentage (%) before the treatment | 32 7 78.12 | 34 19 44.11 | 29 6 79.31 | 35 8 77.14 | 23 4 82.60 | 29 8 72.41 | 32 6 81.25 | 28 8 71.42 | 35 8 77.14 |
Red kind lactogenesis three dissipates and has anticancer setting upright, and enhance immunity is dwindled the tumor body, improves life quality, and the effect that prolongs life cycle is worthy of popularization, and adapts to the patient who is reluctant to accept chemotherapy and operation especially.
Test 5
Model case
Example 1. Chen Baohuas, woman, 32 years old.
The first visit date: on August 5th, 86.
Before patient's menstruation in every month is risen, conscious distending pain of the breast, companion's leucorrhoea grow in quantity, vexed bitter taste.Through ultrasound diagnosis, left breast UIQ has the lump of one 1.5cm * 1.1cm, examines to be cyclomastopathy.Dissipate 28 doses through taking red kind lactogenesis three, distending pain of the breast and lump disappear.
Efficacy evaluation: clinical cure.
Example 2. Liu Ming, woman, 20 years old.
The first visit date: 03 March 21 days
The patient is the children education teacher, finds during health check-up that the breast outer quadrant of going up in a left side has a smooth surface, the clear oval tumor in limit.The row ultrasound diagnosis is examined and is 1.5cm * 1.0cm fibroma, and the patient becomes thin, menoxenia, dysmenorrhea, poor sleep, two side of body overflows, constipation.After taking 60 doses of this medicines, all disease knowing are removed.
Efficacy evaluation: clinical cure.
Example 3. palace A Ying, woman, 30 years old.
The first visit date: on June 16th, 90
Patient's suckling is in the time of 3 months, and because of family quarrel causes depression of QI, sending out is acute mastitis, and two mammary swellings pains are red and swollen.Take medicine after 5 doses, inflammation absorbs, and recovers normal suckling, and 5 doses of the clothes of continuing are again consolidated curative effect with clear waste heat.
Efficacy evaluation: cure.
Example 4. Lee like prunus mume (sieb.) sieb.et zucc., woman, 50 years old.
The first visit date: on December 5th, 2000
The patient is diagnosed as breast carcinoma in Inner Mongol hospital, because of suffering from hypertension and coronary heart disease, fears operation, seeks medical advice in traditional Chinese medical science clinic then.The right breast of having a medical check-up UIQ lump 1.0cm * 0.7cm, matter is hard, and mobility is poor, the axillary gland enlargement.After taking medicine 3 months, the lump deliquescing, after taking medicine continuously 1 year, on inspection, lump disappears.
Curative effect is calmed down: clinical cure.
Conclusion
One, red kind lactogenesis three dissipates by the theory of Chinese medical science and the principles of formulating prescriptions, has the toxin expelling of invigorating blood circulation, hard masses softening and resolving, promoting the circulation of QI to relieve pain, antiinflammatory, detumescence, repercussive, eliminate stagnation and dissolve phlegm, the effect of right supporting anticancer.Use this medicine treatment cyclomastopathy totally 348 examples, total effective rate 97.6%, western medicine group 156 examples, total effective rate is 65%.
Two, red kind lactogenesis three dissipates and treats acute mastitis, mammary duct fistula and tuberculosis of breast 268 examples, and total effective rate is 99%, western medicine group 198 examples, and total effective rate is 89%.
Three, red kind lactogenesis three dissipates and treats mammary gland fibroma 285 examples, total effective rate 98%, western medicine group 103 examples, effective percentage 80%.
Four, red kind lactogenesis three is dissipated in and improves early-stage cancer patient symptom aspect and be better than the western medicine group, red kind lactogenesis three dissipation groups are 63%, the western medicine group is 25%, difference has the significance meaning, illustrate that red kind lactogenesis three dissipations are anticancer and do not hinder healthy energy, the effect of strengthening vital QI to eliminate pathogenic factors is arranged, and the early-stage cancer patient is acceptant.In a word, red kind lactogenesis three dissipates and has anticancer setting upright, and enhance immunity is dwindled the tumor body, improves life quality, and the effect that prolongs life cycle is worthy of popularization, and special adaptation is reluctant to accept the patient of chemotherapy and operation.
Five, red kind lactogenesis three is dissipated in the anticancer process, simultaneously can increase human immunoglobulin, and the anticancer while of western medicine group, has damaged the immune system of human body.
Six, to be dissipated in anticancer toxic and side effects little for red kind lactogenesis three, and indivedual patients just clothes have mild nausea, but after adhering to taking a week, die away mostly, and appetite strengthens, and body weight increases, spiritual amelioration.
Claims (4)
1. Chinese medicine preparation for the treatment of mastopathy is characterized in that this prescription made by following bulk drugs: Radix Salviae Miltiorrhizae 10-30 part, Pseudobulbus Cremastrae Seu Pleiones 20-40 part, Radix Angelicae Sinensis 10-30 part, Radix Clematidis 10-20 part, Radix Curcumae 10-20 part, Fructus Citri Sarcodactylis 10-20 part, rhizoma sparganic 10-30 part, Rhizoma Curcumae 10-30 part, Radix Bupleuri 10-30 part, Scolopendra 5-15 part, Scorpio 5-15 part, Nidus Vespae 10-30 part, Spina Gleditsiae 10-20 part, Radix Semiaquilegiae 10-20 part, Fructus Trichosanthis 20-40 part, Radix Et Rhizoma Rhei 10-30 part, Bulbus Fritillariae Uninbracteatae 10-30 part, tongue snakeweed 20-40 part, Herba Scutellariae Barbatae 20-40 part, Herba Salviae Chinensis 20-40 part, Herba Pteridis Multifidae 20-40 part, Spica Prunellae 20-40 part, Herba Verbenae 20-40 part, Rhizoma Polygoni Cuspidati 10-30 part, the king does not stay 10-30 part, Radix Glycyrrhizae 5-15 part.
2. a kind of Chinese medicine preparation for the treatment of mastopathy according to claim 1 is characterized in that the preferable amount of each crude drug is: 20 parts of Radix Salviae Miltiorrhizaes, 30 parts of Pseudobulbus Cremastrae Seu Pleioness, 20 parts of Radix Angelicae Sinensis, 15 parts of Radix Clematidis, 15 parts of Radix Curcumaes, 15 parts of Fructus Citri Sarcodactylis, 20 parts of rhizoma sparganic, 20 parts of Rhizoma Curcumae, 20 parts of Radix Bupleuri, 10 parts of Scolopendras, 10 parts of Scorpios, 20 parts in Nidus Vespae, 15 parts of Spina Gleditsiae, 15 parts of Radix Semiaquilegiaes, 30 parts of Fructus Trichosanthis, 20 parts of Radix Et Rhizoma Rhei, 20 parts of Bulbus Fritillariae Uninbracteataes, 30 parts of tongue snakeweed, 30 parts of Herba Scutellariae Barbataes, 30 parts of Herba Pteridis Multifidaes, 30 parts of Herba Salviae Chinensiss, 30 parts of hays, 30 parts of Herba Verbenae, 20 parts of Rhizoma Polygoni Cuspidati, the king does not stay 20 parts, 10 parts in Radix Glycyrrhizae.
3. manufacture method for the treatment of the mastopathy preparation, it is characterized in that: Radix Salviae Miltiorrhizae, Pseudobulbus Cremastrae Seu Pleiones, Radix Angelicae Sinensis, Radix Clematidis, Radix Curcumae, Fructus Citri Sarcodactylis, rhizoma sparganic, Rhizoma Curcumae, Radix Bupleuri, Scolopendra, Scorpio, Nidus Vespae, Spina Gleditsiae, Radix Semiaquilegiae, Fructus Trichosanthis, Radix Et Rhizoma Rhei, Bulbus Fritillariae Uninbracteatae, tongue snakeweed, Herba Scutellariae Barbatae, Herba Salviae Chinensis, Herba Pteridis Multifidae, Spica Prunellae, Herba Verbenae, Rhizoma Polygoni Cuspidati, Wang Buliu, Radix Glycyrrhizae pulverize separately are become fine powder, mix well after crossing 120 mesh sieves, routine is made powder, packages spare after the sterilization.
4. Chinese medicine preparation for the treatment of mastopathy is characterized in that this composition of medicine can make tablet, pill, powder, electuary, unguentum, capsule, oral liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006100118545A CN1879857A (en) | 2006-05-08 | 2006-05-08 | Medicinal powder for treating mammary gland disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006100118545A CN1879857A (en) | 2006-05-08 | 2006-05-08 | Medicinal powder for treating mammary gland disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1879857A true CN1879857A (en) | 2006-12-20 |
Family
ID=37518358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2006100118545A Pending CN1879857A (en) | 2006-05-08 | 2006-05-08 | Medicinal powder for treating mammary gland disease |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1879857A (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103800821A (en) * | 2014-01-13 | 2014-05-21 | 姚娟 | Traditional Chinese medicinal composition for treating breast cancer |
| CN104208183A (en) * | 2014-09-12 | 2014-12-17 | 广西中医药大学 | Externally used Yao medicine composition for treating cystic hyperplasia of breasts and preparation method thereof |
| CN104623558A (en) * | 2015-03-09 | 2015-05-20 | 王艳君 | Medicine for soothing liver qi and resolving depression to treat mastitis |
| CN104740327A (en) * | 2015-04-03 | 2015-07-01 | 于国良 | Traditional Chinese medicine composition for treating mastopathy |
| CN104998132A (en) * | 2015-09-06 | 2015-10-28 | 王璐 | Beverage for treating postpartum mastopathy |
| CN105853965A (en) * | 2016-04-27 | 2016-08-17 | 郑耀玲 | Medicine for treating heat-toxicity internal excess type mastitis and preparation method thereof |
| CN107050390A (en) * | 2017-05-01 | 2017-08-18 | 徐士魁 | It is a kind of to treat medicine of tuberculosis of breast and preparation method thereof |
| CN109847039A (en) * | 2019-03-26 | 2019-06-07 | 张莹雯 | A kind of Chinese medicine composition and application thereof for treating breast cancer |
| CN111991536A (en) * | 2020-08-28 | 2020-11-27 | 林国成 | Traditional Chinese medicine formula for treating mastitis and preparation method thereof |
-
2006
- 2006-05-08 CN CNA2006100118545A patent/CN1879857A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103800821A (en) * | 2014-01-13 | 2014-05-21 | 姚娟 | Traditional Chinese medicinal composition for treating breast cancer |
| CN104208183A (en) * | 2014-09-12 | 2014-12-17 | 广西中医药大学 | Externally used Yao medicine composition for treating cystic hyperplasia of breasts and preparation method thereof |
| CN104623558A (en) * | 2015-03-09 | 2015-05-20 | 王艳君 | Medicine for soothing liver qi and resolving depression to treat mastitis |
| CN104740327A (en) * | 2015-04-03 | 2015-07-01 | 于国良 | Traditional Chinese medicine composition for treating mastopathy |
| CN104998132A (en) * | 2015-09-06 | 2015-10-28 | 王璐 | Beverage for treating postpartum mastopathy |
| CN105853965A (en) * | 2016-04-27 | 2016-08-17 | 郑耀玲 | Medicine for treating heat-toxicity internal excess type mastitis and preparation method thereof |
| CN107050390A (en) * | 2017-05-01 | 2017-08-18 | 徐士魁 | It is a kind of to treat medicine of tuberculosis of breast and preparation method thereof |
| CN109847039A (en) * | 2019-03-26 | 2019-06-07 | 张莹雯 | A kind of Chinese medicine composition and application thereof for treating breast cancer |
| CN109847039B (en) * | 2019-03-26 | 2022-01-04 | 张莹雯 | Traditional Chinese medicine composition for treating breast cancer and application thereof |
| CN111991536A (en) * | 2020-08-28 | 2020-11-27 | 林国成 | Traditional Chinese medicine formula for treating mastitis and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1170556C (en) | Chinese medicine for treating neoplasm | |
| CN1879857A (en) | Medicinal powder for treating mammary gland disease | |
| CN1899500A (en) | Acne clearing decoction | |
| CN1915399A (en) | Preparation for treating high blood pressure, high blood fat, obesity, and climacteric syndrome, and preparation method | |
| CN1305513C (en) | Broad-spectrum cancer-treating Chinese medicine prepn and its prepn process | |
| CN101041043A (en) | Liver cancer treating traditional Chinese medicine | |
| CN1285374C (en) | Medicine for treating stomachache caused by qi and cold stagnation and technique for preparing the same | |
| CN1686506A (en) | Medicine for treating mammary gland proliferation, its preparation method and application | |
| CN1965990A (en) | Medicament for preventing and treating benign hyperplasia of mammary glands in women and preparation process thereof | |
| CN101224290B (en) | Chinese traditional medicine for treating breast nodules and preparing method thereof | |
| CN114788858B (en) | Traditional Chinese medicine pill for treating nodules as well as preparation method and application thereof | |
| CN102755515B (en) | Traditional Chinese medicine decoction for treating hyperplasia of mammary glands | |
| CN1864730A (en) | A cancer-treating medicine | |
| CN104547736A (en) | Medicine for treating goiter | |
| CN102488784A (en) | Traditional Chinese medicine composition for treating low back pain | |
| CN1233354C (en) | Chinese medicine preparation for treating carcinoma of esophagus | |
| CN115463200A (en) | Traditional Chinese medicine composition and patch for treating adenoidal hypertrophy and preparation method thereof | |
| CN102552684A (en) | Functional food for treating hyperplasia of mammary glands in women | |
| CN105853930A (en) | Traditional Chinese medicine composition for treating depression | |
| CN101337043B (en) | Traditional Chinese medicine for treating hyperplasia of mammary glands | |
| CN103816522A (en) | Chinese medicament for treating hyperplasia of mammary glands | |
| CN1679908A (en) | Chinese medicine for treating tumor and preparation thereof | |
| CN1256976C (en) | Anti-cancer Chinese medicinal composition and its preparing method | |
| CN1265810C (en) | A pharmaceutical composition for treating cyclomastopathy, and its preparation method | |
| CN1101841A (en) | Chinese medicine Guanxintong for preventing and curing coronary heart disease and angina pectoris, and producing process thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |