CN1874745A - Machine for filling and closing two-part capsules - Google Patents

Machine for filling and closing two-part capsules Download PDF

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Publication number
CN1874745A
CN1874745A CNA2004800327253A CN200480032725A CN1874745A CN 1874745 A CN1874745 A CN 1874745A CN A2004800327253 A CNA2004800327253 A CN A2004800327253A CN 200480032725 A CN200480032725 A CN 200480032725A CN 1874745 A CN1874745 A CN 1874745A
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CN
China
Prior art keywords
capsule
machine
guiding pendulum
guiding
pendulum plate
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Granted
Application number
CNA2004800327253A
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Chinese (zh)
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CN100435769C (en
Inventor
维尔纳·伦法特
瓦尔特·伯林格
雅勒·伯厄
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Robert Bosch GmbH
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Robert Bosch GmbH
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Publication of CN1874745A publication Critical patent/CN1874745A/en
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Publication of CN100435769C publication Critical patent/CN100435769C/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074Filling capsules; Related operations

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Basic Packing Technique (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Supplying Of Containers To The Packaging Station (AREA)
  • Apparatus For Making Beverages (AREA)

Abstract

The invention relates to a machine for filling and closing two-part capsules (C), particularly hard gelatin capsules. The machine comprises a capsule conveying device having cavities (14A) for accommodating one capsule (C) at a time. In addition, the machine comprises at least one capsule ejecting station (XI) that has a capsule ejecting device (19) for axially ejecting the capsules (C) from their respective cavity (14A), has guide flaps (24A, 24B), which can be individually actuated by an actuating device (39), can swivel in relation to a swivel pin (31), are each assigned to a capsule cavity (14a), and which each have two guideways (33A, 34A). Said guideways are provided for the respectively assigned capsule (A)and can be actuated by the actuating device (39). The inventive machine also comprises dividing walls that separate the guideways (33A, 34A) of adjacent guide flaps (24A, 24B) from one another. The dividing walls are each an integrated component of a guide flap (24A, 24B).

Description

Be used to load and the machine of closing two-part capsules
Prior art
The present invention relates to specific definition in the preamble of claim 1 type, be used to load and the machine of closing two-part capsules.
This machine is by open in the reality and be used to make the capsule of being made up of a capsule upper-part and capsule lower member to load for example medicine of powdered in medicine manufacturing field.This machine comprises a plurality of work stations, being placed on a capsule on the conveyer device will be through these work station, and wherein conveyer device for example is made up of first delivery wheel and second delivery wheel that is provided with capsule upper-part receptor that is provided with capsule lower member receptor.
Work station comprises: at least one capsule separating station, and capsule upper-part and glue lower part are separated on this station; Filling station to capsule lower member filling powder; A capsule sealing station is being placed into the capsule upper-part on the capsule lower member on this station again; A capsule inspection point, the capsular quality of check or its filling state on this station; And a capsule discharge station, on this station, make capsule leave the capsule conveyer device.
Capsule is discharged the station and is designed in this wise, promptly according to the capsule quality of in the inspection point, determining can make on the one hand capsule be discharged to one be configured in bad finished product side, to be used for so-called bad capsule be defective capsular container, and can make on the other hand capsule be discharged to one be configured in intact finished product side, to be used for so-called intact capsule be flawless capsular container.Capsule discharge station comprises for this reason: push rod, and they are axially discharged capsule by corresponding receptor; Reach guiding pendulum plate according to the work of track switch mode, they can a relative swinging axle swingingly be supported and respectively have two guide rails, and one of them guide rail disposes to dispose to intact finished product side and another guide rail and can come selected according to corresponding capsular assay to bad finished product side and they.Capsule receptor and guiding pendulum plate can in a row be provided with, wherein to a guiding pendulum of each receptor configuration plate.The number of guiding pendulum plate is corresponding to the number of the capsule receptor of capsule conveyer device.Can individually control these guiding pendulum plates by an operating means that constitutes veneer mechanism.The guide rail of adjacent guiding pendulum plate is separated from each other by dividing plate, and dividing plate constitutes the lateral boundaries of guide rail thus.They be molded over that capsule is discharged on the housing at station and as metal wire knitted, the pectination shim rises, disadvantageously its manufacturing cost height.
Other shortcoming is to form big relatively gap respectively between each guiding pendulum plate and shim, exist danger thus, flawless capsule is retained on the relevant guiding pendulum plate in intact finished product side " adhesively ".
In addition, each guiding pendulum plate is because the configuration of the capsule receptor in the conveyer device and because the unified guiding pendulum plate that constitutes has an own swinging axle, this means to put the assembly cost of plate hight for leading.
Advantage of the present invention
Feature of the present invention, as to have claim 1 preamble, be used for loading and each dividing plate of machine of closing two-part capsules, especially hard gelatin capsule is the whole ingredient of a guiding pendulum plate, this machine has its advantage, be that capsule is discharged the station and can be had a beguine and discharge the housing that the station significantly can simpler manufacturing according to the capsule of the machine of prior art, because no longer need to make the shim between bothersome, that be used as dividing plate, each receptor of capsule conveyer device.
By the cancellation shim, the housing that also makes capsule discharge the station is easier to clean.
The elimination in the gap between the body of a formation guide rail of guiding pendulum plate and adjacent dividing plate, also reduced such danger: for example carry out by mistake making when suction air is supported flawless capsule " adhesively " to be retained in configuration on the guide rail of bad finished product side, reduced significantly because flow for the guide rail flow air of bad finished product side to configuration for the guide rail of intact finished product side by configuration on the guide rail of so-called intact finished product side when giving in configuration.
In a preferred implementing form that helps assembling of machine of the present invention, the guiding pendulum plate that respectively has a track switch function is supported on the common swinging axle.This allows guiding pendulum plate to be pushed onto on the swinging axle as a group when assembling.
Usually the receptor of capsule conveyer device is arranged to two rows that be arranged in parallel, nine capsule receptors of for example every row.In the case, guiding pendulum plate and two binder removal capsule receptors that capsule is discharged the station cooperatively interact, wherein configuration differs from one another to two rows' guiding pendulum plate, and for example be such, promptly stagger on the corresponding contact pin side direction of the relative second guiding pendulum template die of the contact pin of two guide rails of separation of a guiding pendulum template die.
In order to support to discharge in the receptor of capsule by the capsule conveyer device, at least one of the guide rail of each guiding pendulum plate can be air sucked.Usually give the guide rail of bad finished product side under the situation of the guide rail of intact finished product side and the guide rail that bad finished product side is given in configuration air sucked guide rail being divided into a configuration.
When discharging corresponding capsule in by the capsule receptor of capsule conveyer device, the optimum seeking site ground of corresponding guiding pendulum plate is relevant with the corresponding capsule quality or the filling state that are used at least one recording in the capsular inspection point.When a capsule was considered to intact in the inspection point, then corresponding guiding pendulum plate was swung to such position, so that capsule is discharged in the cell therefor for the guide rail of intact finished product side along configuration.If capsule is be evaluated as bad when being defectiveness in the inspection point, then corresponding guiding pendulum plate is swung like this, promptly makes capsule be discharged from for the guide rail of bad finished product side along configuration.The control device of the operating means of guiding pendulum plate preferably cooperatively interacts with capsular inspection point for this reason.
Other advantage of technical scheme of the present invention and favourable configuration can be learnt in accompanying drawing and claims by this description.
Description of drawings
Summary and express according to the embodiment of a machine of the present invention simplifiedly and will describe in detail in the following description in the accompanying drawings.Accompanying drawing is represented:
Fig. 1: the principle vertical view of filling of capsule and sealing machine;
Fig. 2 a: perspective view of discharging the station according to the capsule of the machine of Fig. 1;
Fig. 3: discharge the sectional view that stands in when discharging before the capsule according to the capsule of Fig. 2;
Fig. 4: however with the corresponding view when is assessed as intact capsular capsule and discharges of Fig. 3;
Fig. 5: and a view when one be assessed as bad capsular capsule discharge corresponding with Fig. 3;
Fig. 6: capsule is discharged a perspective view of first and second guiding pendulum plate at station;
Fig. 7:, wherein discharge a bad capsule and discharge an intact capsule by the second guiding pendulum plate by the first guiding pendulum plate according to a vertical view of the guiding of Fig. 6 pendulum plate;
Fig. 8:, wherein respectively discharge an intact capsule by two guiding pendulum plates according to the guiding pendulum plate of Fig. 6;
Fig. 9:, wherein discharge an intact capsule and discharge a bad capsule by the second guiding pendulum plate by the first guiding pendulum plate according to the guiding pendulum plate of Fig. 6;
Figure 10:, wherein respectively discharge a bad capsule by two guiding pendulum plates according to two guiding pendulum plates of Fig. 6;
Figure 11 a: perspective view of the second guiding pendulum plate; And
Figure 12 a: perspective view of the first guiding pendulum plate.
The specific embodiment
Fig. 1 represents that one is used to load and the machine 10 of closed capsule C, each capsule by a capsule lower member CU and capsule upper-part in other words a lid CO form.This machine 10 comprise one as the capsule conveyer device, around the delivery wheel 12 that vertical axis 11 stepping ground rotates, can sail to 12 work station I to XII by it.Capsule conveyer device 12 comprises 12 bearing parts 13 for this reason, is configured with two rows that stagger relatively in the vertical in each bearing part, every row has 5 the receptor 14A or the 14B that are used for a capsule C.
Each work station I to XII of machine 10 has different tasks when filling capsule C.
For example involutory capsule C selects and they is put among first row's the receptor 14A of respective carrier part 13 and second row's the receptor 14B on work station I and II.
, after the once rotation of work station III, there capsule is taken apart at the bearing part 13 of delivery wheel 12 or piece installing, be about to capsule upper-part CO and separate with capsule lower member CU.And on work station III, also detect the quality of the capsule upper-part CO that is placed on the capsule C in the bearing part 13.
When the bearing part 13 that constitutes at two parts sails to work station V with filling capsule C, this work station is a powder filling station that is provided with the aspirator at the dispersive the air gap adjusting device that is used to handle drug products and center in this example, wherein the medicine powder that is seated among the corresponding capsule lower member CU is carried out pneumatic accurate adjustment.
In work station VII and VIII, check its filling state or its quality to being placed on capsule C in the respective carrier part 13.
When delivery wheel 12 or bearing part 13 arrival work station IX, capsule upper-part CO is arranged again with aiming at corresponding affiliated capsule lower member CU.
Bearing part 13 arrives work station X after rotating 30 ° again around axle 11, and this work station is a sealing station.Here capsule upper-part CO is placed on the capsule lower member CU again.
Then bearing part 13 is transported to capsule and discharges station XI, and each capsule C is by being discharged among its receptor 14A and the 14B in this station.
After capsule C was discharged from, bearing part 13 was transported to a cleaning station XII, and it is cleaned the residue of capsule C or is loaded into powder in it in this cleaning station.
Below will describe capsule in detail and discharge station XI by Fig. 2 to 12.
Capsule is discharged station XI and is comprised a housing 15, the bearing part 13 that is leading on the side 16 and be connected within it with delivery wheel 12, and this bearing part is made of a bearing part lower member 17 and a bearing part upper-part 18.But the bearing part lower member 17 of horizontal ground motion is used to receive capsule lower member CU, and the bearing part upper-part 18 that can move both vertically is used to receive capsule upper-part CO.
Below bearing part 13, be provided with a discharger 19, this discharger is connected with a driver 20 and is respectively equipped with a push rod 21 for 10 receptor 14A of bearing part 13 and each of 14B, described push rod can axially move so that discharge corresponding capsule C in corresponding to the first or second receptor 14A that arranges or 14B on the Z, thus, these capsules C upwards is discharged from by its corresponding receptor 14A or 14B respectively.When by they receptor 14A or 14B in when discharging, these capsules C moves through a hole 22 on housing top 23 respectively, so that then by the guiding of track switch type pendulum plate 24A or 24B or be transported to an intact finished product side 25 or be transported to a bad finished product side 26.Intact finished product side 25 is given for and is considered to flawless capsule C in work station VII and VIII.26 of bad finished product sides are given for and are be evaluated as defective capsule C when checking in work station XI.
Intact finished product side 25 comprises first plexiglass tent (Plexiglashaube) 27, and it prevents that capsule C is by discharging among the machine XI and leading to a collection container that is not shown specifically here for intact capsule C.Plexiglass tent 27 constitutes a slide rail on its downside, this slide rail is aimed at the slide rail 28 on the outside that is formed in housing 15.
Bad finished product side 26 comprises one second plexiglass tent (Plexiglas) 29, and it prevents that also capsule C is by being discharged from the machine 10.Plexiglass tent 29 has covered a collecting zone 30, and this collecting zone is formed on the inboard on housing top 23.
Capsule discharge station X has 5 guiding and puts plate 24A and 5 other guiding pendulum plate 24B, and they are supported on the common swinging axle 31, and wherein, pendulum plate 24A and other the guiding of leading pendulum plate 24B alternately arranges front and back.Guiding pendulum plate 24A is configured to be configured receptor 14B to bearing part 21 to the receptor 14A of bearing part 13 and described other guiding pendulum plate 24B.
Each guiding pendulum plate 24A and 24B are connected with an action bars 32A or 32B, can force corresponding guiding pendulum plate 24A and 24B to carry out an oscillating motion by action bars, and it starts by an operating means 39 of here very summarily representing.
But by action bars 32A and 32B operational guidance pendulum plate 24A and 24B, these action bars 32A and 32B are connected with operating means 39, this operating means be used to check the work station VII of capsule C and VIII cooperatively interacts and according to the dislocation of the predetermined guiding of assay pendulum plate 24A or 24B, therefore just predetermined: current capsule C is along which guide rail 33A, 33B, 34A or 34B discharge to intact finished product side 25 or to bad finished product side 26.The operating means 39 that is used for these can be single controllable guiding pendulum plate 24A and 24B comprises the pneumatic linear actuator that be not shown specifically here, for one in each action bars 32A and the 32B configuration pneumatic linear actuator.
These guiding pendulum plate 24A and 24B respectively have two guide rail 33A and 34A or 33B and 34B, and these guide rails constitute by contact pin 35A or the 35B that is arranged essentially parallel to swinging axle 31 orientations.Guide rail 33A and 33B are used for the capsule C from receptor 14A and 14B is transported to intact finished product side 25. Other guide rail 34A and 34B are used for the capsule C from receptor 14A and 14B is transported to bad finished product side 26.
In addition, be configured with dividing plate 36A or the 36B vertically directed with swinging axle 31 on guiding pendulum plate 24A and 24B, these dividing plates are separated from each other the guide rail of adjacent guiding pendulum plate.Dividing plate 36A and 36B are respectively the whole ingredient of corresponding guiding pendulum plate 24A or 24B and therefore process integratedly with corresponding contact pin 35A or 35B.
In Figure 11 and 12 each difference with the guiding shown in independent state pendulum plate 24A and 24B be the layout of contact pin 35A or 35B and constitute thereon guide rail 33A and the configuration of 34A or 33B and 34B, they adapt to the row's that the side direction each other of the receptor 14A of bearing part 13 and 14B staggers layout.
The distance of two adjacent guiding pendulum plate 24A and 24B is defined on the size of a few tenths of millimeter by an annular boss 37A or 37B, these annular boss respectively surround a support holes 38A or 38B, and each guiding pendulum plate 24A or 24B are suspended on the swinging axle 31 by described support holes.
In order to support capsule C to discharge the conveying on the bad finished product side 26 of station XI to capsule, bad in this example finished product side 26 is air sucked.
At Fig. 4, express the different switching position of guiding pendulum plate 24A and 24B in 5 and 7 to 10.According to Fig. 4, in 8 and 9 the dislocation, capsule C is discharged to intact finished product side 25 along guide rail 33A.According to Fig. 5, in 7 and 10 the dislocation, capsule C is discharged to bad finished product side 26 along guide rail 34A.In addition, in the dislocation of guiding pendulum plate 24B, a capsule C who is arranged in the capsule receptor 14B of bearing part 13 is discharged to intact finished product side 25 along guide rail 33B in Fig. 7 and 8.And guiding is put in the dislocation of plate 24B in Fig. 9 and 10, and capsule C is discharged to bad finished product side 26 along guide rail 34B.

Claims (8)

1. the machine that is used for filling and closing two-part capsules (C), be particularly useful for filling and sealing hard gelatin capsule, comprise a capsule conveyer device (12), this capsule conveyer device has the receptor (14A that is used for each capsule (C), 14B), and comprise at least one capsule discharge station (XI), this capsule is discharged station and is comprised:
A capsule discharger (19), be used for by corresponding capsule receptor (14A axially discharges capsule (C) in 14B),
A plurality of that can individually be operated by an operating means (39), can a relative swinging axle (31) the guiding pendulum plate (24A of swing, 24B), their each correspondences are given a capsule receptor (14A, 14B), and they respectively have two can be by guide rail (33A, the 34A of this operating means (39) capsule (C) operation, that be used for described corresponding correspondence; 33B, 34B), and
A plurality ofly be used to separate guiding pendulum plate (24A, guide rail 24B) (33A, 34A adjacent one another are; 33B, dividing plate 34B) (36A, 36B),
It is characterized in that: (36A 36B) is guiding pendulum plate (24A, whole ingredient 24B) to each dividing plate.
2. according to the machine of claim 1, it is characterized in that: (24A 24B) is supported on the common swinging axle (31) these guiding pendulum plates.
3. according to the machine of claim 1 or 2, it is characterized in that: (24A, 24B) (14A's these guiding pendulum plates 14B) cooperatively interacts with two binder removal capsule receptors.
4. according to one machine in the claim 1 to 3, it is characterized in that: (24A's adjacent guiding pendulum plate 24B) separates each other by a gap, and this gap is preferably by adjacent guiding pendulum plate (24A, (37A 37B) determines boss 24B) in the support region of at least one guiding pendulum plate.
5. according to one machine in the claim 1 to 4, it is characterized in that: (24A, (34A, 34B) at least one is air sucked for guide rail 24B) for each guiding pendulum plate.
6. according to one machine in the claim 1 to 5, it is characterized in that: discharger (19) comprises some push rods (21), these push rods dispose respectively to a capsule receptor (14A, 14B).
7. according to one machine in the claim 1 to 6, it is characterized in that: (24A 24B) respectively can be by a pneumatic linear actuator operation for these guiding pendulum plates.
8. according to one machine in the claim 1 to 7, it is characterized in that: (24A, (VII's operating means 24B) (39) VIII) matches with at least one inspection point that is used for capsule (C) to be used for these guiding pendulum plates.
CNB2004800327253A 2003-11-03 2004-10-04 Machine for filling and closing two-part capsules Expired - Fee Related CN100435769C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10351212A DE10351212A1 (en) 2003-11-03 2003-11-03 Machine for filling and closing two-part capsules
DE10351212.8 2003-11-03

Publications (2)

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CN1874745A true CN1874745A (en) 2006-12-06
CN100435769C CN100435769C (en) 2008-11-26

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CNB2004800327253A Expired - Fee Related CN100435769C (en) 2003-11-03 2004-10-04 Machine for filling and closing two-part capsules

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US (1) US20070044433A1 (en)
EP (1) EP1682070B1 (en)
CN (1) CN100435769C (en)
DE (2) DE10351212A1 (en)
WO (1) WO2005041849A1 (en)

Cited By (3)

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CN104554838A (en) * 2013-10-22 2015-04-29 博世包装技术(杭州)有限公司 Pellet filling unit and upper base therefor
CN104146870B (en) * 2014-08-22 2018-01-16 浙江华仕力机械有限公司 Separated-drainage type capsule discharging mechanism
CN108289792A (en) * 2015-11-26 2018-07-17 德国翰辉包装机械有限责任公司 Device for releasing at least one capsule from capsule frame and method

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US20070028560A1 (en) * 2005-08-08 2007-02-08 Darrell Gauthier Machine for filling and closing two-piece capsules
DE102006035280A1 (en) * 2006-07-31 2008-02-07 Robert Bosch Gmbh Device and method for ejecting at least one capsule
DE102008013403A1 (en) * 2008-03-10 2009-09-17 Robert Bosch Gmbh Capsule carrier arrangement for filling and closing machines
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DE102022130430A1 (en) * 2022-11-17 2024-05-23 Syntegon Technology Gmbh Capsule filling machine for filling a capsule and method for operating a capsule filling machine

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104554838A (en) * 2013-10-22 2015-04-29 博世包装技术(杭州)有限公司 Pellet filling unit and upper base therefor
CN104554838B (en) * 2013-10-22 2016-09-07 博世包装技术(杭州)有限公司 Top base and micropill filling device for micropill filling device
CN104146870B (en) * 2014-08-22 2018-01-16 浙江华仕力机械有限公司 Separated-drainage type capsule discharging mechanism
CN108289792A (en) * 2015-11-26 2018-07-17 德国翰辉包装机械有限责任公司 Device for releasing at least one capsule from capsule frame and method
CN108289792B (en) * 2015-11-26 2020-10-30 德国翰辉包装机械有限责任公司 Device and method for ejecting at least one capsule from a capsule holder

Also Published As

Publication number Publication date
DE502004011528D1 (en) 2010-09-23
CN100435769C (en) 2008-11-26
WO2005041849A1 (en) 2005-05-12
DE10351212A1 (en) 2005-06-02
EP1682070B1 (en) 2010-08-11
EP1682070A1 (en) 2006-07-26
US20070044433A1 (en) 2007-03-01

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