CN1835777A - A connecting device, a medical system, and a method of connecting medical subsystems - Google Patents

A connecting device, a medical system, and a method of connecting medical subsystems Download PDF

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Publication number
CN1835777A
CN1835777A CNA200480023455XA CN200480023455A CN1835777A CN 1835777 A CN1835777 A CN 1835777A CN A200480023455X A CNA200480023455X A CN A200480023455XA CN 200480023455 A CN200480023455 A CN 200480023455A CN 1835777 A CN1835777 A CN 1835777A
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China
Prior art keywords
coupling part
pontes
inner space
subsystem
end cap
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CNA200480023455XA
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Chinese (zh)
Inventor
A·维斯兰德
S-B·林德奎斯特
E·布勒姆斯
E·尼尔松
P·谢尔斯特兰德
L·约恩松
O·卡尔松
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Gambro Lundia AB
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Gambro Lundia AB
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Priority claimed from PCT/SE2004/001199 external-priority patent/WO2005016443A1/en
Publication of CN1835777A publication Critical patent/CN1835777A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10Tube connectors; Tube couplings
    • A61M39/16Tube connectors; Tube couplings having provision for disinfection or sterilisation
    • A61M39/18Methods or apparatus for making the connection under sterile conditions, i.e. sterile docking

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • External Artificial Organs (AREA)

Abstract

The invention refers to a medical system comprising a first subsystem with a first connection portion (7), and a second subsystem with a second connection portion (12). The invention also refers to a device and a method for connecting the subsystems to each other. One of the subsystems contains a fluid. The connecting device is adapted to connect the subsystems to each other to permit transport of the fluid from one of the subsystems to the other subsystem. The device comprises a container (21) enclosing an inner space. A substantially sterile atmosphere is provided in the inner space. The container receives the first connection portion and the second connection portion in the inner space. A mechanism is provided for connecting, from outside the container, the first connection portion and the second connection portion to each other in the inner space.

Description

Connection device, medical system and the method that connects medical sub-system
Technical field
The present invention relates generally to the formation of the fluidic aseptic or substantially aseptical condition that is used to operate medical application.
Especially, the present invention relates to a kind of connection device that is used for medical system, described medical system comprises first subsystem with the first pontes, with second subsystem with second coupling part, at least one described subsystem comprises fluid, described connection device is suitable for making described subsystem to be connected to each other to allow described fluid to be transferred to another described subsystem from least one described subsystem, described equipment comprises the container that seals an inner space, and described container is suitable for admitting the first pontes and second coupling part in described inner space.
Further, the present invention relates to a kind of medical system, it comprises: first subsystem with the first pontes; Second subsystem with second coupling part, at least one described subsystem comprises fluid; Connection device, it is suitable for making described subsystem to be connected to each other to allow described fluid to be transferred to another subsystem from least one described subsystem, described connection device comprises the container that seals an inner space, and described container is suitable for admitting the first pontes and second coupling part in described inner space.
Further, the present invention relates to a kind of being used for will have first subsystem of the first pontes and have second subsystem method connected to one another of second coupling part in medical system.
Background technology
In medical field, have many occasions, in these occasions fluid under aseptic condition from a sub-system transmissions to another subsystem to prevent that described fluid or any one described subsystem from being polluted.May use according to of the present invention first, first subsystem can be the system that is used for transfusion is offered patient's blood system.Of the present invention second uses the transmission can be blood products or blood from the blood system of body one by one to another individual blood system, described transmission or directly between described individuality, perhaps by being used for any system of storage of blood, further application of the present invention can comprise medical fluid any supply in individual body.The common aspect of these application is that one of them subsystem is a biosystem, for example Ge Ti blood system.Yet the present invention also can be applicable to the transmission of fluid between two abiotic subsystems, for example during manufacturing, purification, processing or the treatment of medical fluid and during purification, processing or the treatment at biofluid.
Hereinafter, the present invention will be described in conjunction with dialysis, and dialysis is an important application of the present invention.Yet the present invention is not limited to this application, but other field that can be applied to limit above.
Nowadays the main dialysis treatment of Shi Yonging has two kinds, i.e. hemodialysis and peritoneal dialysis.Carry out weekly three times for each blood samples of patients dialysis, and each treatment time is approximately 4 hours.Hemodialysis is carried out in clinic, hospital or similar public organizations usually, and the patient is tied to dialysis apparatus thus, has therefore stoped the patient to participate in any other activity in principle during therapeutic process.
Peritoneal dialysis can be undertaken by patient oneself at home, and the patient can operate the required equipment of this treatment of carrying out.Will be own be connected to dialysis container set and start peritoneal dialysis via being incorporated into conduit in the abdominal cavity by the patient, described dialysis container set comprises litter bag and has the bag of dialysis solution.The liquid that is present in first step in the abdominal cavity is discharged into litter bag, and new then dialysis solution is fed to the abdominal cavity from dialyzate bag.After dialysis solution was introduced into, it approximately spent half an hour, and patient oneself disconnects connection.At certain time durations generation dialysis treatment, the patient can participate in other activity and live normal life in principle during this period then.After described time durations, dialysis solution must be replaced, and the patient is connected own and new dialysis solution thus, to replace the dialysis solution in the abdominal cavity.These operations can be carried out in any suitable place by patient oneself.Therefore, the significant advantage that peritoneal dialysis had is that it has increased the freedom of patient's life, can be preferred Therapeutic Method therefore.
Yet, have continuous use that stops peritoneal dialysis and the problem that must change into hemodialysis.For example, these problems comprise insufficient dialysis and peritonitis.The peritonitis that studies show that of having carried out is the subject matter relevant with peritoneal dialysis.The reason that peritonitis takes place has a lot, and for example, the pollution owing to contact surrounding air produces contacts the pollution that conduit produces, the infection relevant with conduit etc. owing to patient oneself is direct.Owing to the pollution of touching or the air contact produces can take place when dialysis container set is connected with the patient and disconnects.At this connection and off period, have the contaminated risk of conduit, for example by surrounding air, by with patient's skin or with the floor or any around other object directly contact.If conduit is contaminated, antibacterial and other microorganism can be waited for an opportunity to enter in patient's body and be caused peritonitis.
At " Britain medical treatment magazine " (British Medical Journal), the 288th volume, on February 4th, 1984, the 353-356 page or leaf has proposed to carry out in the flexible sterile bag that comprises disinfectant being connected of patient and dialysis container set by pipe end is enclosed in.Yet this method more complicated that proposes is because it comprises the step that many patients of needs carry out.Pipe end will be incorporated in the flexible pouch by opening, then must be at pipeline tighten around opening, so that the inner space of sealing is provided in bag.Have two gauze pieces in described bag, it is used to remove the pipe lid and is used for the described end of sterilization before being connected around being located at described end.
Summary of the invention
An object of the present invention is to improve medical treatment or the connection/disconnection each other of biological subsystem.Further purpose of the present invention provides a kind of controlled environment or the room of cleaning is used to realize the connection/disconnection each other of various medical treatment or biological subsystem.Another purpose of the present invention is to realize a kind of connection/disconnections, and this connection/disconnections can be in a kind of simple and reliable mode by patient's realization and can not bring accidental pollution and touch.Further purpose of the present invention be realize a kind of can be by standardized connection/disconnection.Of the present invention more further purpose be to minimize the number of times that peritonitis takes place during the peritoneal dialysis.Especially, the present invention's risk of being intended to improve being connected of patient and dialysis container set and disconnection and reducing to infect.
Described purpose is realized by the initial connection device that limits, it is characterized in that: described equipment comprises that the user that is suitable for allowing described equipment is implemented in the first pontes and the second coupling part described mechanism that is connected each other the described inner space from the outside of described container.
By such equipment, various medical treatment or the connection each other of biological subsystem can realize with the isolated inner space of surrounding.Carry out the user who connects and do not need to grasp or contact any one coupling part.Thereby compare with in open environment, carrying out situation about being connected, the coupling part that can significantly reduce medical treatment or biological subsystem is subjected to the risk of surrounding air or user's skin contamination.Described mechanism makes the user carry out described connection with a kind of convenience, safe and reliable mode.By equipment according to the present invention, can realize a kind of safe connection/disconnection, be used for peritoneal dialysis, be used for the infusion of infusion solution and/or be used for the infusion of blood products.
According to one embodiment of present invention, described mechanism is suitable for allowing after finishing described connection the user to realize the disconnection of the first pontes from second coupling part from the outside of described container.Therefore, the disconnection each other of same described subsystem can be carried out in clean environment, has reduced the risk that described coupling part is polluted, by and reduced the risk that described subsystem is polluted.
According to further embodiment of the present invention, described equipment comprises the device that is used for providing in described inner space basic aseptic environments.Advantageously, described device can comprise that the permission clean air inwardly flow into the passage in the described inner space.By the adding of such clean air, can in described inner space, produce basic aseptic environments with a kind of convenience and reliable mode.And described device can comprise the filter that is arranged in the described passage, is used for filtering before described gas enters described inner space described gas.Described device can also comprise flow generator (flow generator), is used to provide the described inside air-flow by described passage.Advantageously, described flow generator can be suitable for keeping overvoltage in described inner space.Like this, can prevent to be subjected to the described inner space of air admission that surrounding pollutes.
According to further embodiment of the present invention, described device comprises the disinfectant member that is used for providing to the inner space of described container disinfectant.Rely on such disinfectant member, can reduce to be present in the microbial numbers in the described inner space.Further reduced to be connected to the risk that the patient produces pollution by described coupling part.
According to further embodiment of the present invention, at least one in the first pontes and second coupling part combines with the protection end cap.Preferably, described arrangement of mechanism becomes to allow to remove described end cap from the described coupling part that combines before described connection.And described mechanism can be arranged to allow after described disconnection described end cap to be connected to the described coupling part that combines.
According to further embodiment of the present invention, described container can be opened to open mode and be introduced in described inner space to allow entering described inner space and permission the first pontes and second coupling part.So described container can comprise base component and openable lid, when described end is correctly located with beginning is suitable be connected before described being placed on be to be closed.
According to further embodiment of the present invention, described equipment comprises and being arranged in the described inner space to admit at initial position and to keep first of the first pontes to admit element, with be arranged in the described inner space to admit at initial position and to keep second of second coupling part to admit element, wherein said mechanism is suitable for moving first and admits element and second at least one of admitting in the element, makes the first pontes and second coupling part be connected to each other in described inner space.Rely on such equipment, therefore can by described container closure and forms controlled environment or the described inner space of cleaning sterilizing room in carry out whole attended operations with mode easily easily with a kind of.Under open mode, the user can be positioned at the end of first pipeline in the corresponding admittance element.First admits element can also be arranged to engage simultaneously the first pontes and second end cap, and second admits element can be arranged to engage simultaneously second coupling part and first end cap.By such structure, will be in described inner space rotate in opposite direction described coupling part, is convenient to each end cap constantly and is removed when described admittance element moves separation thus.And, so described end can be connected to each other by being moved toward each other after removing described end cap and after the lateral displacement.
According to further embodiment of the present invention, described mechanism comprises first operating element and second operating element.According to the present invention, can rely on described two operating elements to produce and finish necessary all motions of described connection.
First end cap is usually screwed onto the first end, and second end cap is usually screwed onto the second end.According to further embodiment of the present invention, second operating element be arranged to described initial position rotate in first end cap and the first pontes one with discharge first end cap from the first pontes and rotate second end cap and second coupling part in one to discharge second end cap from second coupling part.Like this can be released by described end cap before really removing from described coupling part separately at described end cap.Advantageously, then first operating element can be arranged to described initial position move first admit element and second admit in the element one so that they away from each other, to finish first and second end caps removing from separately coupling part.Preferably, in the described admittance element moves described initial position described and comprises along moving of principal direction substantially longitudinally.Preferably, described principal direction is parallel to the extension of pipeline described in the described inner space.
According to further embodiment of the present invention, second operating element is arranged to move to link position with one in the first and second admittance elements from described initial position.Advantageously, second operating element is arranged to carry out the described of described link position fully at described end cap after separately end is removed and moves.One described link position in the described admittance element described moved and can comprise along moving of second direction substantially longitudinally.Preferably, second direction is perpendicular to the extension at pipeline described in the described inner space, thereby perpendicular to described principal direction.By moving, will cause described end aligned with each other at described link position along this of second direction.
According to further embodiment of the present invention, first operating element is arranged to move first along the longitudinal direction that is parallel to described principal direction at described link position and admits element and second at least one of admitting in the element, makes the second end engage first end.After this, second operating element can be arranged to rotate in first end and the second end one being connected with assurance first end and the second end after described link position carries out described move.
According to further embodiment of the present invention, first operating element comprises handle portion, and this handle portion is located at the outside of described container so that can be engaged by the people who uses described equipment.And second operating element can comprise handle, and this handle is located at the outside of described container so that can be engaged by the people who uses described equipment.
Described purpose is also realized by the initial medical system that limits, it is characterized in that: described equipment comprises that the user that is suitable for allowing described equipment is implemented in the first pontes and the second coupling part described mechanism that is connected each other the described inner space from the outside of described container.Described system can comprise any one in the feature that limits above.
According to a preferred embodiment, first subsystem comprises dialysis fluid container, second subsystem comprises that being suitable for operationally part is arranged in patient's body and extends to conduit in the abdominal cavity, described conduit forms second coupling part, and wherein said medical system is to be used for peritoneal dialysis, to be used for the infusion of infusion solution and/or to be used for the medical system of the infusion of blood products.
Described purpose also realizes that by the initial method that limits it may further comprise the steps:
The container of sealing one inner space is provided,
Basic aseptic environments is provided in described inner space,
The first pontes and second coupling part are incorporated in the described inner space,
Rely on a kind of mechanism to realize the first pontes and second coupling part described connection the each other from the outside of described container to allow at least one from subsystem of fluid to be transferred to another subsystem.
The step of favourable further method is defined in dependent claims 34-50.
Description of drawings
To and be described in greater detail with reference to the attached drawings the present invention according to the description of various embodiment now.
Figure 1A schematically discloses according to a kind of medical system of the present invention.
Figure 1B schematically discloses PDS according to an embodiment of the invention.
Fig. 2 schematically discloses the side view of the end of two pipelines in the system that is included in Fig. 1.
Fig. 3 schematically discloses the forward perspective view of the connection device that is in closed condition in the system that is included in Fig. 1.
Fig. 4 schematically discloses connection device back to perspective view of Fig. 3.
Fig. 5 schematically discloses the forward perspective view of the connection device of the Fig. 3 that is in open mode.
Fig. 6 schematically discloses the cutaway view by the connection device of Fig. 3.
Fig. 7-19 schematically discloses the inner space of connection device during different Connection Steps.
The specific embodiment
Figure 1A discloses a kind of medical system 100, and it comprises first subsystem 101 with the first pontes 4, second subsystem 102 and the connection device 20 with second coupling part 5.First subsystem 101 can be the system that for example is used to provide medical treatment or biofluid or liquid under given conditions, and described liquid will be transferred to the patient or be used to store any device of described liquid.Described liquid can comprise transfusion, blood, dialysis solution or any liquid medicine.Second subsystem 102 can comprise and be used for described medical treatment or biofluid are transferred to the receiver, for example patient's device.Second subsystem 102 can also comprise the device that is used to store described liquid.Connection device 20 is suitable for subsystem 101 and 102 is connected to each other, and 101,102 is transferred to another subsystem 101,102 along at least one direction from subsystem to allow described medical treatment or biofluid.
Figure 1B discloses a kind of medical system of PDS form, and wherein first subsystem 101 comprises dialysis container set, and this dialysis container set comprises the waste fluid container of flexible litter bag 1 form and the dialysis fluid container of flexible dialyzate bag 2 forms.In the bag 1 and 2 each is respective flexible conduit 1a, the 2a by being connected to valve 3 all.Valve 3 is connected to the first pontes 4.The first pontes 4 comprises first pipeline 6 with first end 7, referring to Fig. 2.First pipeline 6 adopts the form of first flexible pipe and axis a extension along the longitudinal.
Second subsystem 102 comprises second coupling part 5 of conduit form, and this second coupling part operationally part is arranged in patient's body with in the abdominal cavity 8 that extends to the patient.Described conduit forms second pipeline 11 of flexible pipe form.Second pipeline 11 has the second end 12 of axis b extension along the longitudinal, referring to Fig. 2.In the disclosed embodiment, the second end 12 has and connects protuberance 13, and this connection protuberance is designed to be incorporated in the connection recess 14 of first end 7 so that first pipeline 6 is connected to each other with second pipeline 11 is in the same place.Connect the forward direction external screw thread 15 that protuberance 13 has the corresponding female thread 16 in the recess 14 that is arranged to be connected with a joggle.Connect protuberance 13 so can be moved to and be connected in the recess 14 along the longitudinal direction that is parallel to longitudinal direction a and b.When mobile end, at least one described end rotation makes screw thread 15 and 16 be engaged with each other.So pipeline 6 and 11 is connected to each other securely.
In order to protect end 7 and 12, the first pipelines 6 to combine with first end cap 17 that is releasably connected to first end 7, second pipeline 11 combines with second end cap 18 that is releasably connected to the second end 12, referring to Fig. 2.First end cap 17 has the shape corresponding to the connection protuberance 13 of the second end 12, thereby be directed in the connection recess 14 of first end 7 and be screwed to securely on the screw thread 16.Second end cap 18 has the shape corresponding to the connection recess 14 of first end 7, thereby can be connected on the connection protuberance 13 of the second end 12 and be screwed to securely on the screw thread 15.
And described system comprises the connection device 20 of the connection between the second end 12 of the first end 7 that is used to carry out first conduit 6 and second conduit 11.Explain the structure and the function of connection device 20 below in more detail.The patient is connected to dialysis container set with oneself under the help of connection device 20 when using described system.Valve 5 is adjusted to exhaust position, and wherein the liquid in the abdominal cavity 8 is discharged in the litter bag 1 by pipeline 11,6 and 3.Valve 5 is adjusted to supply position then, and wherein dialysis solution is fed to abdominal cavity 8 from dialyzate bag 2 by pipeline 4,6 and 11.The patient disconnects oneself under the help of connection device 20 then.
Connection device 20 comprises the container 21 that seals an inner space, referring to Fig. 3-6.Container 21 is designed to be in basic closed condition during using connection device 20, referring to Fig. 3,4 and 6, thereby prevents that surrounding air from arriving described inner space.Container 21 can be opened to open mode, referring to Fig. 5, to allow to enter described inner space and the first end 7 of permission introducing first pipeline 6 and the second end 12 of second pipeline 11.In the disclosed embodiment, container 21 comprises base component 22 and can open and covers 23.Container 21 can rely on locking member 24 to be locked in closed condition.
And connection device 20 comprises the device that is used for providing in described inner space basic aseptic environments.Described device can comprise various parts.In the disclosed embodiment, described device comprises flow generator.Described flow generator is installed in the shell 25 and comprises fan 26 or the similar device in shell 25.Shell 25 is located in the container 21 and is arranged at least at the connection and the off period of described end and produces inside air-flow in the described inner space that enters container 21 when container 21 is in closed condition, described air-flow can be by self-cleaning, the aseptic substantially air source of access road 27 or from surrounding air, referring to Fig. 4.Especially in the latter case, filter 28 can be located at the downstream of fan 26 on the shell 25, is used for filtering before the inner space of air admission container 21 described inside air-flow.Preferably a kind of filter that prevents that multiple microorganism from passing through of filter 28, thus cleaning, basic aseptic environments can in described inner space, be formed.Described flow generator will produce overvoltage in described inner space, enter surrounding air but allow air communication to cross the described inner space of two outlets, 29 outflows, referring to Fig. 3.Should be noted that container 21 can be suitable for holding another gas that is different from air, for example such as nitrogen, such pure gas or the admixture of gas of carbon dioxide.Under these circumstances, access road 27 can be connected to and comprise any suitable gas or the source of the gas (unexposed) of admixture of gas.
Shall also be noted that fan 26 or any other suitable flow generator can be arranged to provide overvoltage in the described inner space of container 21.By such overvoltage, prevent that the noxious air from the outside from entering the described inner space of container 21, and prevent to pollute the described inner space and the parts that are included in wherein of described container.
Preferably, during fan 26 is activated certain hour before suitable connection procedure begins, so that guarantee in the described inner space of container 21, to obtain cleaning, basic aseptic environments.The length of described time durations depends on various factors, the flow resistance of the turbulent flow in for example described inner space, the size of described fan and power, filter 28 etc.Described time durations for example can be in 1 second to 10 seconds the scope.
Described device can also be included in the disinfectant member 29 that schematically illustrates among Figure 1B, and this disinfectant member is suitable for disinfectant is fed in the described inner space of container 21.As shown in Figure 1B, disinfectant member 29 can integrally be installed to container 21 or externally.Described disinfectant can provide by passage 27 or by the independent pipeline 29a that has nozzle in described inner space, and described nozzle is used for the aerosol in the spray disinfectant agent of described inner space preferably in described filter downstream.Described disinfectant member 29 can be suitable for the disinfectant with automated manner supply dose, for example certain time durations before each connection procedure.
Preferably, described disinfectant allows the described time durations of effect in described inner space, for example a few minutes, allows effectively to reduce antibacterial or any other microorganism that may survive in the described inner space thus.As selecting or replenish, described disinfectant member 29 can be suitable for the manual supply of described disinfectant, and the button 29b that for example relies on the patient to push is with the described sprinkling of the aerosol of beginning disinfectant.
In order to realize the connection each other of aforesaid described end, connection device 20 also comprises a kind of mechanism that will be explained in more detail below.Described mechanism comprises first operating element, and this first operating element also has handle portion 35, and this handle portion is located at the outside of described container 21 so that can be engaged by the people who uses described equipment.Described mechanism also comprises second operating element, and this second operating element also has handle 36, and this handle is located at the outside of described container 21 so that can be engaged by the people who uses described equipment.In order to simplify, first operating element and second operating element are also represented with Reference numeral 35 and 36 respectively.
In order to allow pipeline 6 and 11 to extend in the container 21, provide to be used for first elongated pore 31 of first pipeline 6, referring to the Fig. 5 and the second almost circular hole 32, referring to Fig. 4, to extend through container 21.When container 21 was in open mode, hole 31,32 was easy to targeted duct 6 and 11.First admits element 41 to be disposed in described inner space in first hole 31, referring to Fig. 5.Second admits element 42 to be disposed in described inner space in second hole 32.First admits element 41 to have be used to admit and keep first pipeline 6 first end 7 first chamber 43 and be used to admit and keep being connected to second chamber 44 of second end cap 18 of the second end 12.Second admits element 42 to have be used to admit and keep second pipeline 11 the second end 12 first chamber 45 and be used to admit and keep being connected to second chamber 46 of first end cap 17 of first end 7.Described chamber is provided with such as key or the such mechanism of groove, is used to keep corresponding element, and promptly described end and end cap make that these elements can be around axle a and b rotation separately.
First admits element 41 to comprise two major part 41a and 41b.Part 41a is arranged in the base component 22, and part 41b is arranged in and covers in 21.When container 21 is in open mode, this two part 41a and 41b thereby separated from one another, referring to Fig. 5, but when described container was in closed condition, these two parts were adjacent to each other, referring to Fig. 6.The first end 7 and second end cap 18 thereby can be sandwiched in the corresponding chamber 43,44 between described two part 41a and the 41b.
Equally, second admit element 42 to comprise two major part 42a and 42b.These two part 42a and 42b are arranged in the base component 22.Part 42a forms the top that is pivotally connected to part 42b, and part 42b forms the bottom that is connected to base component 22.When container 21 was in open mode, this two part 42a and 42b thereby separated from one another were referring to Fig. 5.Top 42a can rely on locking member 47 to be fixed in the position of bottom 42b.The second end 12 and first end cap 17 can be sandwiched in the corresponding chamber 45,46 between described two part 42a and the 42b.
Chamber 43,44 admits the corresponding rotatable teeth parts 50,51 in the element 41 to form by being included in first.Therefore, in the time of in being positioned at the first corresponding chamber 43,44 of admitting in the element 41, the first end 7 and second end cap 18 can be rotated.Rely on these rotations, end cap 17 and 18 can unclamp from end 7 and 12 separately.This rotation relies on second operating element to realize, this second operating element comprises described teeth parts 50,51, prolongs double sided rack 52, first gear 53 and second gear 54.Tooth bar 52 can rely on first gear 53 to move in a longitudinal direction.First gear 53 can rely on second gear, 54 rotations that are connected to handle 36.Thereby can improve handle 56 and rotate the first end 7 and second end cap 18 by disclosed starting position from Fig. 6 from initial position.
As the situation among Fig. 5,6 and 7, when first admitted element 41 to be in initial position, the part of determining in an only rotatable week of teeth parts 50 and 51 was approximately 270 ° in the disclosed embodiment.After this rotation, thus locked prevention of teeth parts 50,51 anyly further move.After this rotation, described handle is in vertical position, referring to Fig. 9.The further motion of handle 36 will cause second to admit element 42 to move to link position from initial position along second direction y, referring to Figure 11.
Second admit element 42 can initial position along the longitudinal principal direction x rely on the handle portion 35 of first operating element to move.Second admits the motion of element by guide rod 60 guiding, referring to Fig. 5.First operating element comprises and connects two bars 61 that handle portion 35 and second is admitted element and extended through described container.And, referring to Figure 12, securing rod 62 is connected to the second admittance element 42 and may extend in first first opening of admitting in the element 41 63, referring to Fig. 6, be used for admitting element 41 to be locked in initial position with first, and may extend in first second opening of admitting in the element 41 64, to admit element 41 to be locked in to be used to the link position of the rotation that obtains said gear element 50,51 with first.Described principal direction x is substantially perpendicular to second direction y.Second admits element 42 thereby can admit element 41 and mobile backward towards the first admittance element 41 away from first.
Especially with reference to figure 7-19, will explain the function of connection device 20 in more detail now.Should be noted that container 21 is disclosed in the open state in all Fig. 7-19, although in fact container 21 is closed in the most Connection Steps shown in these figure.Container 21 is disclosed in the open state the function that is arranged in the element in the connection device 20 just to demonstration.
Fig. 7 discloses first pipeline 6 and first end 7 and has been positioned at first and admits in first chamber 43 of element 41, and second pipeline 11 and the second end 12 are positioned at second and admit in first chamber 45 of element 42.Simultaneously, first end cap 17 is positioned in second and admits in second chamber 46 of element 42, and second end cap 18 is positioned in first and admits in second chamber 44 of element 41.After this location, second admits the top 42a of element 42 to be pivoted to the closed position and to pass through locking member 47 lockings.After this, lid 23 is closed and is locked in closed condition by locking member 24.
Fig. 8 has shown except covering 23 different elements that are in closed condition opening.
Fig. 9 discloses next procedure, and wherein handle 36 rotates to vertical position from the starting position.This rotation of handle 36 causes the rotation of teeth parts 50 and 51, this means 270 ° of first end 7 and 18 rotations of second end cap.By this rotation, end cap 17 and 18 screw thread will break away from the screw thread 16,15 of first end 7 and the second end 12 respectively.Because this operation that gets loose has second of first end cap 17 and the second end 12 and admits element 42 outwards to move along described principal direction x.Therefore, first operating element and handle portion 35 also will outwards move along described principal direction x.
After this, further along the outside moving handle part 35 manually of described principal direction x, as shown in Figure 10.Because this motion, first end cap 17 and the second end 12 will break away from the first end 7 and second end cap 18 fully.And securing rod 62 will break away from first and admit element 42.Other device that should be noted that first operating element that this motion can be by being different from handle portion 35 is realized, for example by spring or other like.
Figure 11 discloses next procedure, and wherein handle 36 further rotates to terminal location from vertical position.This motion of handle 35 wherein first admits element 41 to be unlocked, will cause first admit element 41 along the longitudinal second direction y move to link position from initial position.In described link position, the longitudinal axis a of first end 7 will aim at the longitudinal axis b of the second end 12.
After this, handle portion 35 back moves along described principal direction x, and as disclosed among Figure 12, wherein the connection protuberance 13 of the second end 12 is introduced in the connection recess 14 of first end 7.
Figure 13 discloses next procedure, and wherein handle 36 rotates to vertical position from terminal location, thereby teeth parts 50 and first end 7 are rotated.Because this rotation, the screw thread 15 of the second end 12 will mesh the screw thread 16 of first end 7, the feasible safe and reliable connection that realizes between two pipelines 6 and 11.In this stage, can begin initial described treatment and can carry out fluid exchange.When finishing described treatment, lid 23 can be opened, and second end cap 18 is removed, but keeps first end cap 17.After this, new end cap 18 is introduced in the corresponding position, and container 21 is closed once more.
Figure 14 discloses the initial step of the disconnection of two pipelines 6 and 11.At first step, handle 36 rotates to terminal location from vertical position, and wherein screw thread 14 and 15 breaks away from each other.First operating element and handle portion 35 a little outwards move along described principal direction x simultaneously.
Figure 15 discloses next procedure, and wherein handle portion 35 further outwards moves so that first end 7 and the second end 12 break away from each other fully along described principal direction x.
In Figure 16 in the disclosed next procedure, handle 36 moves to vertical position from terminal location, wherein first admits element 41 to be brought back to initial position from link position.
Figure 17 discloses following step, and wherein handle portion 35 back moves along described principal direction x, thereby first end cap 17 is introduced in the first end 7, and the second end 12 is introduced in second end cap 18.
Figure 18 discloses last step, and wherein handle 36 moves to the starting position from vertical position, and wherein end cap 17 and 18 screw thread mesh the screw thread 16 and 15 of first end 7 and the second end 12 respectively.After this, end cap 17 and 18 is connected to end 7,12 separately securely, thereby container 21 can open, and can take out duct elements 6,11 from connection device 20.
The present invention is not limited to described embodiment, but can change in the scope of appended claim and revise.
Should be noted that for example replacing moving first along second direction y admits element 41, the second to admit element 42 to be moved along this direction.Described rotation can be admitted in the element 42 but not admit in the element 41 first and be carried out second.Yet, allow first pipeline 6 rotation that is not connected to the patient be favourable.

Claims (50)

1. connection device that is used for medical system, described medical system comprises have the first pontes first subsystem (101) of (4), with second subsystem (102) with second coupling part (5), at least one described subsystem comprises fluid, described connection device (20) is suitable for making described subsystem (101,102) be connected to each other to allow described fluid to be transferred to another described subsystem from least one described subsystem
Described equipment (20) comprises the container (21) that seals an inner space, and described container (21) is suitable for admitting the first pontes (4) and second coupling part (5) in described inner space,
It is characterized in that: described equipment comprises that the user that is suitable for allowing described equipment is implemented in the first pontes (4) and second coupling part (5) the described mechanism that is connected each other the described inner space from the outside of described container (21).
2. equipment according to claim 1 is characterized in that: described mechanism is suitable for allowing after finishing described connection the user to realize the disconnection of the first pontes (4) from second coupling part (5) from the outside of described container (20).
3. equipment according to claim 1 and 2 is characterized in that: described equipment comprises the device (26-29) that is used for providing in described inner space basic aseptic environments.
4. equipment according to claim 3 is characterized in that: described device (26-29) comprises that the permission clean air inwardly flow into the passage (27) in the described inner space.
5. equipment according to claim 4 is characterized in that: described device (26-29) comprises the filter (28) that is arranged in the described passage, is used for filtering before described gas enters described inner space described gas.
6. according to claim 4 or 5 described equipment, it is characterized in that: described device (26-29) comprises flow generator (26), is used to provide the described inside air-flow by described passage (27).
7. equipment according to claim 6 is characterized in that: described flow generator is suitable for keeping overvoltage in the described inner space of described container (21).
8. according to arbitrary described equipment among the claim 3-7, it is characterized in that: described device (26-29) comprises the disinfectant member (29) that is used for providing to the inner space of (21) of described container disinfectant.
9. according to the described equipment of the arbitrary claim in front; wherein at least one in the first pontes (4) and second coupling part (5) with the protection end cap (17; 18) combine; it is characterized in that: described arrangement of mechanism becomes to allow before described connection from the described coupling part that combines (4; 5) remove described end cap (17,18).
10. according to claim 2 and 9 described equipment, it is characterized in that: described arrangement of mechanism becomes to allow described end cap (17,18) to be connected to the described coupling part that combines (4,5) after described disconnection.
11. according to the described equipment of the arbitrary claim in front, it is characterized in that: described container (21) can be opened to open mode and be introduced in the described inner space to allow entering described inner space and permission the first pontes (4) and second coupling part (5).
12. equipment according to claim 11 is characterized in that: described container (21) comprises base component (22) and openable lid (23).
13. according to the described equipment of the arbitrary claim in front, it is characterized in that: described equipment comprises:
Be arranged in the first admittance element (41) that is used for admitting and keeping the first pontes (4) in the described inner space at initial position,
Be arranged in the second admittance element (42) that is used for admitting and keeping second coupling part (5) in the described inner space at initial position,
Wherein said mechanism is suitable for moving first and admits element (41) and second at least one of admitting in the element (42), makes the first pontes (4) and second coupling part (5) be connected to each other in described inner space.
14. according to the described equipment of the arbitrary claim in front; wherein the first pontes (4) be used to protect first end cap (17) of the first pontes (4) to combine; second coupling part (5) be used to protect second end cap (18) of second coupling part (5) to combine, it is characterized in that: described arrangement of mechanism becomes to allow first end cap (17) removing and second end cap (18) removing from second coupling part (5) from the first pontes (4) before described connection.
15. equipment according to claim 14, it is characterized in that: first admits element (41) to be arranged to engage simultaneously the first pontes (4) and second end cap (18), and second admits element (42) to be arranged to engage simultaneously second coupling part (5) and first end cap (17).
16. according to the described equipment of the arbitrary claim in front, it is characterized in that: described mechanism comprises first operating element (35) and second operating element (36).
17. according to claim 15 and 16 described equipment, it is characterized in that: first end cap (17) is screwed onto on the first pontes (4), second end cap (18) is screwed onto on second coupling part (5), it is characterized in that: second operating element is arranged to rotate in first end cap (17) and the first pontes (4) one discharging first end cap (17) from the first pontes (4) at described initial position, and rotates in second end cap (18) and second coupling part (5) one with from second coupling part (5) release, second end cap (18).
18. equipment according to claim 17, it is characterized in that: first operating element (35) be arranged to described initial position move first admit in the element (41) and the second admittance element (42) at least one so that they away from each other, thereby finish first and second end caps (17,18) removing from separately coupling part (4,5).
19. equipment according to claim 18 is characterized in that: at least one in the described admittance element (41,42) comprises along the motion of principal direction (x) substantially longitudinally described the moving of described initial position.
20. according to arbitrary described equipment among the claim 16-19, it is characterized in that: second operating element (36) is arranged to move to link position with one in the first admittance element (41) and the second admittance element (42) from described initial position.
21. according to claim 18 and 20 described equipment, it is characterized in that: second operating element (36) is arranged at described end cap (17,18) move to the described of described link position from carrying out in the described admittance element (41,42) one after separately coupling part (4,5) is removed fully.
22. according to claim 20 or 21 described equipment, it is characterized in that: described moving to described link position in the described admittance element (41,42) comprises along the motion of second direction (y) substantially longitudinally.
23. according to claim 19 and 22 described equipment, it is characterized in that: described principal direction (x) is basically perpendicular to described second direction (y).
24. according to arbitrary described equipment among the claim 19-23, it is characterized in that: first operating element (35) is arranged to move first along the longitudinal direction that is parallel to described principal direction (x) at described link position and admits element (41) and second at least one of admitting in the element (42), makes second coupling part (4) engage the first pontes (5).
25. equipment according to claim 24, it is characterized in that: second operating element (36) is arranged to rotate in the first pontes (4) and second coupling part (5) after described link position carries out described move, with being connected of assurance the first pontes (4) and second coupling part (5).
26. according to arbitrary described equipment among the claim 16-25, it is characterized in that: first operating element comprises handle portion (35), and this handle portion is located at the outside of described container (21), so that can be engaged by the people who uses described equipment.
27. according to arbitrary described equipment among the claim 16-26, it is characterized in that: second operating element comprises handle (36), and this handle is located at the outside of described container (21), so that can be engaged by the people who uses described equipment.
28. according to the described equipment of the arbitrary claim in front, it is characterized in that: first subsystem (101) comprises dialysis fluid container (1,2), second subsystem (102) comprises that being suitable for operationally part is arranged in patient's body and extends to conduit in the abdominal cavity (8), and described conduit forms second coupling part.
29. a medical system, it comprises:
First subsystem (101) with the first pontes (4);
Have second subsystem (102) of second coupling part (5), at least one described subsystem comprises fluid; With
Connection device (20), it is suitable for making described subsystem (101,102) to be connected to each other, and is transferred to another described subsystem to allow described fluid from least one described subsystem,
Described connection device (20) comprises the container (21) that seals an inner space, and described container (21) is suitable for admitting the first pontes (4) and second coupling part (5) in described inner space,
It is characterized in that: described equipment comprises that the user that is suitable for allowing described equipment is implemented in the first pontes (4) and second coupling part (5) the described mechanism that is connected each other the described inner space from the outside of described container (21).
30. a medical system, it comprises:
First subsystem (101) with the first pontes (4);
Have second subsystem (102) of second coupling part (5), at least one described subsystem comprises fluid; With
Connection device (20), it is suitable for making described subsystem (101,102) to be connected to each other, and is transferred to another described subsystem to allow described fluid from least one described subsystem,
Described connection device (20) comprises the container (21) that seals an inner space, with the device (26-28) that is used for providing basic aseptic environments in described inner space, described container (21) is suitable for admitting the first pontes (4) and second coupling part (5) in described inner space
It is characterized in that: described equipment (20) is included in the feature of arbitrary qualification among the claim 1-26.
31. according to claim 29 or 30 described medical systems, it is characterized in that: first subsystem (101) comprises dialysis fluid container (1,2), second subsystem (102) comprises that being suitable for operationally part is arranged in patient's body and extends to conduit in the abdominal cavity (8), and described conduit forms second coupling part (5).
32. according to arbitrary described medical system among the claim 29-31, it is characterized in that: described medical system is to be used for peritoneal dialysis, to be used for the infusion of infusion solution and/or to be used for the medical system of the infusion of blood products.
33. one kind is used for will having first subsystem of the first pontes and having second subsystem method connected to one another of second coupling part in medical system, wherein at least one described subsystem comprises fluid, said method comprising the steps of:
The container of sealing one inner space is provided,
The first pontes and second coupling part are incorporated in the described inner space,
Rely on a kind of mechanism to be implemented in the first pontes and second coupling part described connection the each other the described inner space from the outside of described container, be transferred to another described subsystem from least one described subsystem to allow described fluid.
34. method according to claim 33, it further may further comprise the steps:
After finishing described connection, rely on described mechanism to realize the disconnection of the first pontes from the outside of described container from second coupling part.
35. according to claim 33 or 34 described methods, it further may further comprise the steps:
Basic aseptic environments is provided in described inner space.
36. method according to claim 35, it further may further comprise the steps:
The inside air-flow of the clean air that enters in the described inner space is provided by passage.
37. method according to claim 36, it further may further comprise the steps:
Before entering described inner space, filters described gas described gas.
38. according to arbitrary described method among the claim 33-37, it further may further comprise the steps:
In described inner space, supply disinfectant.
39. according to arbitrary described method among the claim 33-38, wherein at least one in the first pontes and second coupling part combines with the protection end cap, described method further may further comprise the steps:
Before described connection, remove described end cap from the described coupling part that combines.
40. according to arbitrary described method among the claim 34-39, it further may further comprise the steps:
After described disconnection, described end cap is connected to the coupling part that combines.
41. according to arbitrary described method among the claim 33-40, it further may further comprise the steps:
Open described container,
The first pontes and second coupling part are incorporated in the described inner space,
The coupling part is positioned in the described inner space, and closes described container.
42. according to arbitrary described method in the claim 41, wherein said location may further comprise the steps:
The first pontes being positioned at first at initial position in described inner space admits in the element;
Second coupling part being positioned at second at initial position in described inner space admits in the element.
43. according to the described method of claim 42, wherein said connection may further comprise the steps:
Admit element and second to admit in the element at least one to move to link position with first to realize described the connection.
44. according to claim 33 or 43 described methods; wherein the first pontes be used to protect first end cap of the first pontes to combine; second coupling part be used to protect second end cap of second coupling part to combine, said method comprising the steps of:
Before described connection, remove first end cap, and remove second end cap from second coupling part from the first pontes.
45. according to claim 42 and 44 described methods, wherein first end cap is screwed onto on the first pontes, second end cap is screwed onto on second coupling part, said method comprising the steps of:
Rotate in first end cap and the first pontes one at described initial position, discharging first end cap from the first pontes,
Rotate in second end cap and second coupling part one at described initial position, with discharge from second coupling part second end cap and
Described initial position along the longitudinal principal direction move first admit element and second admit in the element at least one so that they away from each other, thereby finish described first and second end caps removing from separately coupling part.
46. according to arbitrary described method among the claim 42-45, it may further comprise the steps:
Fully after separately coupling part is removed, second direction admits in the elements at least one to move to link position from described initial position with first and second along the longitudinal at described end cap.
47. according to the described method of claim 46, it may further comprise the steps:
Move first along longitudinal direction at described link position and admit element and second at least one of admitting in the element, make the second end engage the first pontes perpendicular to described second direction.
48. according to the described method of claim 47, it may further comprise the steps:
After described link position carries out described move, rotate first and admit element and second in admitting, with being connected of assurance the first pontes and second coupling part.
49. according to arbitrary described method among the claim 33-48, wherein first subsystem comprises dialysis fluid container, second subsystem comprises that being suitable for operationally part is arranged in patient's body and extends to conduit in the abdominal cavity, and described conduit forms second coupling part.
50. according to the described method of claim 49, wherein said medical system is to be used for peritoneal dialysis, to be used for the infusion of infusion solution and/or to be used for the medical system of the infusion of blood products.
CNA200480023455XA 2003-08-15 2004-08-16 A connecting device, a medical system, and a method of connecting medical subsystems Pending CN1835777A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE0302225A SE0302225L (en) 2003-08-15 2003-08-15 A connecting device, a medical system, and a method of connecting medical subsystems
SE03022258 2003-08-15
US60/536,175 2004-01-12
PCT/SE2004/001199 WO2005016443A1 (en) 2003-08-15 2004-08-16 A connecting device, a medical system, and a method of connecting medical subsystems

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CN1835777A true CN1835777A (en) 2006-09-20

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105209107A (en) * 2013-05-20 2015-12-30 通用电气健康护理生物科学股份公司 Apparatus and method for making a sterile connection of flexible tubing
CN106029117A (en) * 2013-12-20 2016-10-12 弗雷泽纽斯医疗保健德国有限公司 Container
CN109303940A (en) * 2017-07-28 2019-02-05 泰尔茂株式会社 Medical connector dismounts auxiliary implement
TWI657835B (en) * 2018-01-24 2019-05-01 國立台灣大學醫學院附設醫院雲林分院 Peritoneal dialysis connection device and method thereof
CN110446510A (en) * 2017-03-22 2019-11-12 日机装株式会社 Medical connector
CN114288485A (en) * 2021-12-31 2022-04-08 常州市武进人民医院 Pipeline butt joint operation bin for peritoneal dialysis

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105209107A (en) * 2013-05-20 2015-12-30 通用电气健康护理生物科学股份公司 Apparatus and method for making a sterile connection of flexible tubing
CN105209107B (en) * 2013-05-20 2019-03-12 通用电气健康护理生物科学股份公司 Device and method for carrying out the disinfection connection of flexible pipe
CN106029117A (en) * 2013-12-20 2016-10-12 弗雷泽纽斯医疗保健德国有限公司 Container
CN106029117B (en) * 2013-12-20 2019-12-03 弗雷泽纽斯医疗保健德国有限公司 Container
CN110446510A (en) * 2017-03-22 2019-11-12 日机装株式会社 Medical connector
CN110446510B (en) * 2017-03-22 2022-03-29 日机装株式会社 Medical connector
CN109303940A (en) * 2017-07-28 2019-02-05 泰尔茂株式会社 Medical connector dismounts auxiliary implement
CN109303940B (en) * 2017-07-28 2022-11-15 泰尔茂株式会社 Medical connector dismounting auxiliary device
TWI657835B (en) * 2018-01-24 2019-05-01 國立台灣大學醫學院附設醫院雲林分院 Peritoneal dialysis connection device and method thereof
CN114288485A (en) * 2021-12-31 2022-04-08 常州市武进人民医院 Pipeline butt joint operation bin for peritoneal dialysis

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SE0302225L (en) 2005-02-16

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