CN1803117A - In vitro stress stimulator for promoting lower limb bone healing - Google Patents
In vitro stress stimulator for promoting lower limb bone healing Download PDFInfo
- Publication number
- CN1803117A CN1803117A CN 200510045457 CN200510045457A CN1803117A CN 1803117 A CN1803117 A CN 1803117A CN 200510045457 CN200510045457 CN 200510045457 CN 200510045457 A CN200510045457 A CN 200510045457A CN 1803117 A CN1803117 A CN 1803117A
- Authority
- CN
- China
- Prior art keywords
- hammer
- stimulator
- lower limb
- motor
- fracture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Landscapes
- Surgical Instruments (AREA)
- Percussion Or Vibration Massage (AREA)
Abstract
The invention discloses an external stress stimulator to promote the assimilation of lower limb bone, which comprises the following parts: case, level groove bracket on one side of case, motor in the case, hammer and control circuit, wherein the connection wheel is fixed on the motor rotary shaft; the hammer rod top is hinged in the top of case with sliding hole in the middle of hammer rod; the slider is set in the sliding hole to move up and down, which is fixed at the eccentric position of connection wheel; the hammer hole is opened on the case in front of the hammer head, which contains level groove of bracket. The invention transmits the motor power into hammer power to control the stress and frequency, which stimulates the patient fracture end reciprocally and periodically.
Description
Technical field
The present invention relates to a kind of external stress stimulator that promotes lower limb bone healing, particularly relate to a kind ofly be applicable to that femoral shaft, the dried fresh fracture of tibia, old fracture, bone are damaged, fracture delayed union, nonunion, complication such as fracture back osteoporosis and hip joint, the early stage external stress stimulator of knee prosthesis postoperative.
Background technology
The lower limb shaft fracture comprises that fracture of shaft of femur, tibia are done, tibiofibula is done fracture.The fracture at these positions often easily causes fracture delayed union, nonunion, fracture end bony defect etc. for various reasons.Bone delay in healing, nonunion are meant the sluggish of fracture healing process and stop.No matter operative treatment or non-operative treatment and hip joint, knee prosthesis postoperative after the fracture, because of the unstressed stimulation of fracture end easily causes knitting speed to slow down and osteoporotic appearance, due to illness the required bed rest time of people is long again, expense is high, patient's misery and burden have been increased, so how to accelerate the process of knitting, treatment bone delay in healing, nonunion, bony defect are very significant problems, also are one of the emphasis of orthopaedics area research and difficult point always.At present, stimulate union of fracture both at home and abroad, the method for treatment fracture delayed union, bone does not connect is a lot, mainly contain mechanical stress stimulation, electromagnetic stimulation, supersonic vibration stimulate, from body bone and allogenic bone transplantation and organizational project etc.Though electromagnetic stimulation is operative treatment not, electromagnetic stimulation has the possibility of guide pin fracture, pin site infection, and externally-applied magnetic field produces eddy-current heating on the metal inside-fixture patient such as do not feel well; Supersonic vibration stimulates the curative effect of knitting also to have many disputes; Though do not have the immunological rejection of xenogenesis bone from the body bone, supply limitedly, and wound is big, the chance that increases the patient suffering and infect for the district; The xenogenesis bone only can play bone conduction effect, makes the speed of growth of bone graft slow; Also studied organizational project in recent years,, search out difficulty of ideal cell source and host material, and immunological rejection may occur though it holds out broad prospects.These methods be because of providing necessary stress stimulation to fracture end, often cause complication such as fracture end osteoporosis to occur because of long-term bed and braking.There is numerous research to support that knitting is regulated and control by local mechanical environment.Many in recent years bases and clinical research confirm that all the controlled small movements of fracture end can promote callus formation and calcification, can the accelerated bone healing.The mechanical stress stimulus method promotes union of fracture to be admitted by Chinese scholars as a kind of Noninvasive therapy.Therefore it is clinical how to stimulate the theoretical research result of union of fracture to be applied to mechanical stress, and by the process of mechanics approach accelerating union of bone fracture, orthopaedics diseases such as treatment fracture delayed union, bone does not connect have very important significance.
At present, stimulate the research of union of fracture all on the zoopery basis, to carry out mostly about mechanical stress, immediate corpse or the femur of just adopting, even if but verity is good, corpse does not have regeneration capacity yet, for considering that the influence of mechanical stress to union of fracture has little significance, that is to say, mechanical stress is to help union of fracture in theory, but temporarily be not used for clinical medicine, fairly perfect instrument also not occurring directly applies in the fracture recovering medical treatment, but mechanical stress promotes the union of fracture theory to obtain general approval, in case the exploitation and the application of the Medical Instruments of fracturing are accordingly achieved success, the research of union of fracture and clinical treatment will obtain important breakthrough.
Summary of the invention
The objective of the invention is to overcome the deficiency of prior art, provide a kind of reasonable in design, operate simple and easy, light, safe stress stimulation promotes the instrument of knitting, can accelerated bone the process of healing, shorten treatment time, treatment fracture delayed union, nonunion, bone are damaged, complication such as control fracture back osteoporosis are avoided the possibility of wound, misery and infection that operative treatment causes.
The technical solution adopted for the present invention to solve the technical problems is: a kind of external stress stimulator that promotes lower limb bone healing, and it comprises the instrument shell, is connected in the horizontal slot carriage of instrument shell one side and is contained in motor, hand hammer in the instrument shell and the control circuit that is used for drive motors; Described motor is connected with a fifth wheel with the top in being fixed on the instrument shell before and after the axis on the machine shaft; Described hand hammer comprise along about to tup that is provided with and the vertical hammer stem that is provided with, an end of hammer stem and tup Joint, the other end are articulated in the interior top of shell; Middle part at hammer stem is provided with slide opening, is with the slide block that can move up and down along slide opening in the slide opening, and slide block is fixed on the eccentric position place of fifth wheel; The front end of described tup is made as circular-arc, is provided with the hammer hole along the move instrument shell in the place ahead of tup, and the hammer hole feeds the level trough of carriage.
Described control circuit comprises switching power circuit, signal generator and the motor driver that contains rectification, voltage stabilizing, the input of switching power circuit is connected to the 220V alternating current power supply, the output of switching power circuit is connected to signal generator, motor driver respectively, the output of signal generator is connected to motor driver, and the output of motor driver is connected to motor.
Described motor is a motor.
Vertical being articulated in described hammer stem and the instrument shell to being articulated by a bearing, the end of hammer stem is fixed in the inner ring or the place, outer ring of bearing, and the outer ring of bearing or inner ring are fixed on the top in the instrument shell.
Described slide block is a bearing, and the inner ring of bearing is fixed on the eccentric position of fifth wheel, and the outer ring of bearing is enclosed within the slide opening.
Described hand hammer is that medical stainless steel material is made, and the hand hammer top is made as circular arc.
Described carriage is that medical stainless steel material is made, and is horizontal slot.
External stress stimulator of the present invention, be control circuit and the hand hammer that motor, drive motors running are housed in the instrument shell, by motor power being converted into hand hammer power, make the hand hammer top repeatedly, periodically along the hammer hole outwards hit, patient's lower limb are placed on the carriage, heel portion is near the hammer hole, just can allow the hand hammer top repeatedly, periodicity is perpendicular to the human body heel, act on heel along the lower limb y direction.
Its circuit structure of external stress stimulator of the present invention is not limit, with can control step motor rotation speed, running intermittent time get final product.
Controllable stress intensity of its hand hammer of external stress stimulator of the present invention and stress frequency size all within human body institute energy tolerance scope, can be set at 20N～350N and 0.1Hz～40Hz respectively.
The present invention stimulates according to the osseous tissue counter stress to have good adaptability, the mechanical environment of fracture plays the theory of regulating and controlling effect to knitting, and the principle of utilizing electromechanical integration, the a kind of of development is used to promote union of fracture, the control bone delay in healing, nonunion, bone is damaged, fracture back osteoporosis, quicken hip joint, the stress stimulator of knee prosthesis postoperative knitting, impose suitable stress by this instrument to suffering from the limb heel, make fracture end produce small activity, to excite knitting potential, reach the treatment fracture, bone delay in healing, the purpose of orthopaedics diseases such as nonunion.
In the use, in the level trough that patient's lower limb are placed on, allow the patient heel portion near the hammer hole, after turning on the power switch, motor gets electric rotation, motor has driven the fifth wheel rotation after rotating, after rotating, fifth wheel drives and then rotation together of the fixed slide block of eccentric position on it again, because hammer stem is nested by slide opening and slide block, and the upper end of hammer stem is positioned in the top in the instrument shell, and then the rotation of slide block has driven the swing of hammer stem, certainly will will drive tup after the hammer stem swing and seesaw, thereby make tup repeatedly along the hammer hole, periodically outwards hit and act on patient's heel, reached the effect that stimulates patient's fracture end.
During use, select case according to this instrument indication.Symptomatic treatment such as dewater after being admitted to hospital for fresh lower limb shaft fracture, plaster slab is temporarily fixing, after swelling is disappeared, after the fracture end local anesthesia, the closed manual reduction of row fracture, plaster cast is fixed, and checks reset case the same day; Old lower limb shaft fracture be admitted to hospital the same day row manual reduction and plaster cast fix; The bone delay in healing of intramedullary nail with nail postoperative, the capable release postoperative of nonunion need not be fixed by plaster cast; Plaster cast fixedly case heel position is opened a Gypsum Fibrosum window, and the about 4.5cm of diameter exposes heel portion skin; To suffer from limb and be put on the stress stimulation knitting instrument bracket, heel is aimed at stress stimulation knitting instrument stress delivery outlet.Stress frequency and stress intensity that fracture of shaft of tibia, tibiofibula are done the treatment of fracture case are adjusted to 0.5Hz, 200N respectively, and the stress frequency and the stress intensity of the treatment of fracture of shaft of femur case are adjusted to 0.5Hz, 250N respectively.Treat each treatment time 30min, each 3h at interval every day 3 times.The positive side of check fracture position X-ray film weekly, the amount of assessment growth of spur, and, make fracture end to reach the fastest healing rate and healing quality according to the size of the suitable regulating action stress of amount of callus.
The invention has the beneficial effects as follows: owing to adopted instrument shell, carriage, motor, hand hammer and control circuit to come the constituting body external carbuncle to stimulate instrument, this stimulates knitting instrument to produce compressive stress at long bone fracture end or the damaged end of bone, bone delay in healing end, compressive stress has been acknowledged as and can not only have improved the knitting rate, shorten treatment time, and can reduce or the generation of complication such as bone delay in healing, bone does not connect and osteoporosis afterwards that prevents to fracture, thereby shorten patient's hospital stays, alleviate the patient medical expense; It is complete AT Therapeutic Method that the applied ontology external carbuncle stimulates instrument, can avoid the possibility of wound, misery and infection that operative treatment causes; Be not subjected to the local soft tissue condition influence, simple, convenient; The body external carbuncle stimulates the development cost of instrument low, small investment, and damaged, bone delay in healing of bone or fracture patient number are huge in addition, and the body external carbuncle stimulates appearance easily to be promoted in hospitals at different levels, is easy to be accepted by numerous medical personnels and patient.Therefore, in case the body external carbuncle stimulates instrument clinical trial success, practical value and economic worth that this instrument can be created are very considerable.
Description of drawings
Below in conjunction with drawings and Examples the present invention is described in further detail; But a kind of external stress stimulator of lower limb bone healing that promotes of the present invention is not limited to embodiment.
Fig. 1 is a structural map of the present invention;
Fig. 2 is a vertical view of the present invention;
Fig. 3 is the cutaway view along A-A line among Fig. 2;
Fig. 4 is the cutaway view along B-B line among Fig. 2;
Fig. 5 is a circuit diagram of the present invention.
The specific embodiment
Shown in accompanying drawing, a kind of external stress stimulator that promotes lower limb bone healing of the present invention, it comprises instrument shell 1, is connected in the horizontal slot carriage 2 of instrument shell one side and is contained in motor 3, hand hammer 4 in the instrument shell and the control circuit that is used for drive motors.
Top in the instrument shell 1 is fixed with a support 11 that is used to install motor 3, be provided with hammer hole 12 in instrument shell 1 and carriage 2 joining one sides, hammer hole 12 feeds the level trough of carriage 2, is provided with switch and button in the front of instrument shell 1, is used to control the adjustment of power supply open and close and motor rotation pattern.
Control circuit comprises switching power circuit 61, signal generator 62 and the motor driver 63 that contains rectification, voltage stabilizing, the rectification of switching power circuit 61 by inside, voltage stabilizing components and parts are converted into required unidirectional current with the 220V alternating current of input and offer circuit and use, simultaneously, the switch in it comprises switch that power supply is controlled and the button that is used for conditioning signal; Signal generator 62 is used to produce square-wave signal, sends the pulse speed with control; Motor driver 63 is used for the drive motors running.The input of switching power circuit 61 is connected to the 220V alternating current power supply, and the output of switching power circuit 61 is connected to signal generator 62, motor driver 63 respectively, and the output of signal generator 62 is connected to motor driver 63, and the output of motor driver 63 is connected to motor 3.The structure of control circuit can be not limited to kind of a mode, with can control step motor rotation speed, the running intermittent time gets final product.
External stress stimulator of the present invention, be control circuit and the hand hammer 4 that motor 3, drive motors running are housed in instrument shell 1, by motor 3 power are converted into hand hammer 4 power, tup 41 tops that make hand hammer 4 repeatedly, periodically outwards hit along hammer hole 12, patient's lower limb are placed on the carriage 2, heel portion is near hammer hole 12, just can allow hand hammer 4 tup 41 tops repeatedly, periodicity is perpendicular to the human body heel, act on heel along the lower limb y direction.
Its hand hammer 4 controllable stress intensities of external stress stimulator of the present invention and stress frequency size all within human body institute energy tolerance scope, can be set at 20N～350N and 0.1Hz～40Hz respectively.
The present invention stimulates according to the osseous tissue counter stress to have good adaptability, the mechanical environment of fracture plays the theory of regulating and controlling effect to knitting, and the principle of utilizing electromechanical integration, the a kind of of development is used to promote union of fracture, the control bone delay in healing, nonunion, bone is damaged, fracture back osteoporosis, quicken hip joint, the stress stimulator of knee prosthesis postoperative knitting, impose suitable stress by this instrument to suffering from the limb heel, make fracture end produce small activity, to excite knitting potential, reach the treatment fracture, bone delay in healing, the purpose of orthopaedics diseases such as nonunion.
In the use, in the level trough that patient's lower limb are placed on, allow the patient heel portion near the hammer hole 12, after turning on the power switch, motor 3 gets electric rotation, having driven fifth wheel 31 after motor 3 rotates rotates, after rotating, fifth wheel 31 drives and then rotation together of the fixed bearing 51 of eccentric position on it again, because hammer stem 42 is nested by slide opening 43 and bearing 51, and the upper end of hammer stem 42 is positioned in the top in the instrument shell 1, then the rotation of bearing 51 has driven the swing of hammer stem 42, certainly will will drive tup 41 after hammer stem 42 swings seesaws, thereby make tup 41 repeatedly along hammer hole 12, periodically outwards hit and act on patient's heel, reached the effect that stimulates patient's fracture end.
During use, select case according to this instrument indication.Symptomatic treatment such as dewater after being admitted to hospital for fresh lower limb shaft fracture, plaster slab is temporarily fixing, after swelling is disappeared, after the fracture end local anesthesia, the closed manual reduction of row fracture, plaster cast is fixed, and checks reset case the same day; Old lower limb shaft fracture be admitted to hospital the same day row manual reduction and plaster cast fix; The bone delay in healing of intramedullary nail with nail postoperative, the capable release postoperative of nonunion need not be fixed by plaster cast; Plaster cast fixedly case heel position is opened a Gypsum Fibrosum window, and the about 4.5cm of diameter exposes heel portion skin; To suffer from limb and be put on the stress stimulation knitting instrument bracket, heel is aimed at stress stimulation knitting instrument stress delivery outlet.Stress frequency and stress intensity that fracture of shaft of tibia, tibiofibula are done the treatment of fracture case are adjusted to 0.5Hz, 200N respectively, and the stress frequency and the stress intensity of the treatment of fracture of shaft of femur case are adjusted to 0.5Hz, 250N respectively.Treat each treatment time 30min, each 3h at interval every day 3 times.The positive side of check fracture position X-ray film weekly, the amount of assessment growth of spur, and, make fracture end to reach the fastest healing rate and healing quality according to the size of the suitable regulating action stress of amount of callus.
Claims (7)
1. external stress stimulator that promotes lower limb bone healing is characterized in that: it comprises the instrument shell, is connected in the horizontal slot carriage of instrument shell one side and is contained in motor, hand hammer in the instrument shell and the control circuit that is used for drive motors; Described motor is connected with a fifth wheel with the top in being fixed on the instrument shell before and after the axis on the machine shaft; Described hand hammer comprise along about to tup that is provided with and the vertical hammer stem that is provided with, an end of hammer stem and tup Joint, the other end are articulated in the interior top of shell; Middle part at hammer stem is provided with slide opening, is with the slide block that can move up and down along slide opening in the slide opening, and slide block is fixed on the eccentric position place of fifth wheel; The front end of described tup is made as circular-arc, is provided with the hammer hole along the move instrument shell in the place ahead of tup, and the hammer hole feeds the level trough of carriage.
2. a kind of external stress stimulator that promotes lower limb bone healing according to claim 1, it is characterized in that: described control circuit comprises switching power circuit, signal generator and the motor driver that contains rectification, voltage stabilizing, the input of switching power circuit is connected to the 220V alternating current power supply, the output of switching power circuit is connected to signal generator, motor driver respectively, the output of signal generator is connected to motor driver, and the output of motor driver is connected to motor.
3. a kind of external stress stimulator that promotes lower limb bone healing according to claim 1, it is characterized in that: described motor is a motor.
4. a kind of external stress stimulator that promotes lower limb bone healing according to claim 1, it is characterized in that: vertical being articulated in described hammer stem and the instrument shell to being articulated by a bearing, the end of hammer stem is fixed in the inner ring or the place, outer ring of bearing, and the outer ring of bearing or inner ring are fixed on the top in the instrument shell.
5. a kind of external stress stimulator that promotes lower limb bone healing according to claim 1, it is characterized in that: described slide block is a bearing, and the inner ring of bearing is fixed on the eccentric position of fifth wheel, and the outer ring of bearing is enclosed within the slide opening.
6. a kind of external stress stimulator that promotes lower limb bone healing according to claim 1 is characterized in that: described hand hammer is that medical stainless steel material is made, and the hand hammer top is made as circular arc.
7. a kind of external stress stimulator that promotes lower limb bone healing according to claim 1 is characterized in that: described carriage is that medical stainless steel material is made, and is horizontal slot.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100454575A CN100394904C (en) | 2005-11-28 | 2005-11-28 | In vitro stress stimulator for promoting lower limb bone healing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100454575A CN100394904C (en) | 2005-11-28 | 2005-11-28 | In vitro stress stimulator for promoting lower limb bone healing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1803117A true CN1803117A (en) | 2006-07-19 |
| CN100394904C CN100394904C (en) | 2008-06-18 |
Family
ID=36865358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005100454575A Expired - Fee Related CN100394904C (en) | 2005-11-28 | 2005-11-28 | In vitro stress stimulator for promoting lower limb bone healing |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100394904C (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106038258A (en) * | 2016-07-07 | 2016-10-26 | 重庆市宝富鑫科技开发有限公司 | Complete intelligent physiotherapy blood pressure-reducing health care robot |
| CN106176178A (en) * | 2016-08-31 | 2016-12-07 | 张平 | A kind of pulsed joint mechanical load therapeutic instrument |
| CN111035546A (en) * | 2020-02-14 | 2020-04-21 | 朱波 | Light mechanical arm type massager |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86205190U (en) * | 1986-07-19 | 1987-12-16 | 吉林省吉林中西医结合医院 | Multi-functional medical instrument for bone treatment |
| US5186163A (en) * | 1991-11-25 | 1993-02-16 | The Kendall Company | Compression device |
| JP3396861B2 (en) * | 1993-09-07 | 2003-04-14 | 林原 健 | Tapping shoulder |
| AUPP693698A0 (en) * | 1998-11-05 | 1998-12-03 | Hile, Mark Steven | Resonant frequency stimulator and recorder |
| JP2000157600A (en) * | 1998-11-27 | 2000-06-13 | Motoko Kimoto | Sole stepping device |
-
2005
- 2005-11-28 CN CNB2005100454575A patent/CN100394904C/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106038258A (en) * | 2016-07-07 | 2016-10-26 | 重庆市宝富鑫科技开发有限公司 | Complete intelligent physiotherapy blood pressure-reducing health care robot |
| CN106176178A (en) * | 2016-08-31 | 2016-12-07 | 张平 | A kind of pulsed joint mechanical load therapeutic instrument |
| CN111035546A (en) * | 2020-02-14 | 2020-04-21 | 朱波 | Light mechanical arm type massager |
| CN111035546B (en) * | 2020-02-14 | 2021-08-17 | 李欣欣 | Light mechanical arm type massager |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100394904C (en) | 2008-06-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| McCarthy et al. | Distraction osteogenesis of the craniofacial skeleton | |
| EP0865258B1 (en) | Telescopic bone plate for use in bone lengthening by distraction osteogenesis | |
| HK1037910A1 (en) | Use of creatine compounds for treatment of bone or cartilage cells and tissues | |
| Tavakoli et al. | Distraction osteogenesis in craniofacial surgery: a review | |
| Peacock et al. | Automated continuous distraction osteogenesis may allow faster distraction rates: a preliminary study | |
| CN100394904C (en) | In vitro stress stimulator for promoting lower limb bone healing | |
| Hatefi et al. | Review of physical stimulation techniques for assisting distraction osteogenesis in maxillofacial reconstruction applications | |
| Troulis et al. | Distraction osteogenesis: Past, present, and future | |
| Li et al. | Extracorporeal shock wave therapy: A potential adjuvant treatment for peri-implantitis | |
| RU2311144C2 (en) | Method for treating unhealed fractures and false joints of shin bones complicated with chronic traumatic osteomyelitis | |
| PRITCHETT | L-dopa in the treatment of nonunited fractures. | |
| CN214415206U (en) | Axial stress stimulation healing promotion equipment after fracture operation | |
| CN214129914U (en) | Transverse mechanical stimulator for lower limb fracture rehabilitation | |
| RU2005506C1 (en) | Method of treating children suffering from perthes disease | |
| CN107280814A (en) | Joint prosthesis | |
| RU2382614C1 (en) | Method of treating fractures of long tubular bones | |
| RU2250789C2 (en) | Method for treating the cases of bone injuries under retarded consolidation | |
| RU2193868C2 (en) | Method for stimulation of reparative osteogenesis | |
| RU2405484C1 (en) | Method of surgical treatment of osteomyelitis of distal part of radial bone | |
| El-Bialy | Applications of therapeutic ultrasound in dentistry and in the craniofacial area: Present and future | |
| El-Bialy | A rea: P resent A nd F uture | |
| POPKOV et al. | ORTHOPAEDIC GENIUS | |
| RU2221595C2 (en) | Method for applying hip joint endoprosthesis to treat progressive and chronic destructive tuberculous arthritis of hip joint | |
| RU21510U1 (en) | DEVICE FOR OSTEOSYNTHESIS OF THE PROXIMAL FEM DEPARTMENT | |
| RU2454962C1 (en) | Method of optimising conditions of knitting of fractions of extremity bones and their consequences in conditions of their immobilisation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Double Engine Medical Material Co., Ltd. Assignor: Ding Zhenqi Contract record no.: 2011350000002 Denomination of invention: In vitro stress stimulator for promoting lower limb bone healing Granted publication date: 20080618 License type: Exclusive License Open date: 20060719 Record date: 20110112 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20080618 Termination date: 20181128 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |