CN1785403A - Jindan gallbladder stone dissolving capsule - Google Patents

Abstract

A Chinese medicine ''Jindan calculus-dissolving capsule'' for treating cholelithiasis is prepared from 18 Chinese-medicinal materials including bear gall, red sage root, tangerine peel, rhubarb, etc.

Description

Jindan gallbladder stone dissolving capsule

Technical field

The invention belongs to a kind of pharmaceutical product, particularly a kind of Jindan gallbladder stone dissolving capsule that is used for the treatment of liver and bile stone disease.

Background technology

Cholelithiasis is surgical common disease and frequently-occurring disease, is commonly considered as due to cholestasis, biliary tract antibacterial and the parasitic infection, and wherein the cholesterol imbalance also is a principal element.The removing means of generally taking to perform the operation are at present treated more, and not only patient is painful big, and medical expense is quite high, has increased the weight of patient's burden.The litholytic Chinese medicine that is used for that is seen in report also has, but all has the thorough inadequately and slow drawback of lithodialysis.

(patent No.: 01128739.X), although also liver and bile stone is had therapeutical effect preferably, it is complicated that its prescription is disliked slightly, and the compatibility reasonability is not good enough at the Litholysizing bear gall powder of calendar year 2001 application for one of inventor.

Summary of the invention

The present invention seeks on the basis of the aforementioned invention of inventor, prescription to be deleted and adjusted, further optimize and provide a kind of by the oral pure Chinese medicinal preparation that dissolves liver and bile stone.

Jindan gallbladder stone dissolving capsule of the present invention is to be made by the raw material of following weight portion:

Herba Lysimachiae 6-180, Herba Artemisiae Scopariae 6-15, Endothelium Corneum Gigeriae Galli 10-20, Fructus Aurantii 6-10, Radix Salviae Miltiorrhizae 10-25, Pericarpium Citri Reticulatae 10-25, Rhizoma Cyperi 6-10, Radix Curcumae 10-30, Radix Glycyrrhizae 5-10, Radix Clematidis 10-60, Fel Ursi 5-15, Folium Pyrrosiae 10-30, Radix Et Rhizoma Rhei 10-20, Natrii Sulfas 10-15, Fructus Crataegi 10-15, Radix Bupleuri 6-10, Rhizoma Chuanxiong 10-20, Fructus Jujubae 10-20.

The preferential prescription of recommending of the present invention is:

Herba Lysimachiae 50-120, Herba Artemisiae Scopariae 8-12, Endothelium Corneum Gigeriae Galli 13-17, Fructus Aurantii 8-12, Radix Salviae Miltiorrhizae 17-22, Pericarpium Citri Reticulatae 17-22, Rhizoma Cyperi 8-12, Radix Curcumae 18-25, Radix Glycyrrhizae 5-10, Radix Clematidis 30-40, Fel Ursi 5-15, Folium Pyrrosiae 18-25, Radix Et Rhizoma Rhei 15-18, Natrii Sulfas 10-15, Fructus Crataegi 10-15, Radix Bupleuri 6-10, Rhizoma Chuanxiong 15-18, Fructus Jujubae 10-20.

With encapsulated behind above medicine levigation, sieve 100 orders, mixing, the disinfection by ultraviolet light, make powder, honeyed pill or the watered pill and all can.

The effect that the present invention has the gentle stomach of depressed liver-energy dispersing and QI regulating, anti-inflammatory and choleretic, spleen invigorating, the stasis of blood of reducing phlegm, melts liver and bile stone is used for residual stone, choledocholithiasis, gallbladder hydrops after liver and bile stone, acute and chronic cholecystitis, the operation, significant curative effect is arranged.The characteristics that have no wound, no pain, take medicine conveniently, have no side effect, lithagogue rate are high.

The preparation that the inventor utilizes the present invention to fill a prescription is treated cholelithiasis 120 examples altogether, calculus 81 examples (accounting for 67.50%) that all disappear, and calculus is dwindled 33 examples (accounting for 27.5%), and calculus does not obviously reduce 6 examples (accounting for 5%).Total effective rate reaches 95%.The present invention simultaneously and German medicine AIHUO DANTONG are made 102 routine contrast tests and are shown that also the present invention has significant difference than it.

The specific embodiment

Embodiment 1: with following raw material of Chinese medicine through screening, clean and pulverize the back and cross 300 mesh sieves, encapsulatedly promptly become preparation of the present invention.

Herba Lysimachiae 6, Herba Artemisiae Scopariae 15, Endothelium Corneum Gigeriae Galli 10, Fructus Aurantii 10, Radix Salviae Miltiorrhizae 10, Pericarpium Citri Reticulatae 25, Rhizoma Cyperi 6, Radix Curcumae 30, Radix Glycyrrhizae 5, Radix Clematidis 60, Fel Ursi 5, Folium Pyrrosiae 30, Radix Et Rhizoma Rhei 10, Natrii Sulfas 15, Fructus Crataegi 10, Radix Bupleuri 10, Rhizoma Chuanxiong 10, Fructus Jujubae 20.

Embodiment 2: following raw material of Chinese medicine is crossed 300 mesh sieves through screening, cleaning with after pulverizing, and making honeyed pill promptly becomes preparation of the present invention.

Herba Lysimachiae 180, Herba Artemisiae Scopariae 6, Endothelium Corneum Gigeriae Galli 20, Fructus Aurantii 6, Radix Salviae Miltiorrhizae 25, Pericarpium Citri Reticulatae 10, Rhizoma Cyperi 10, Radix Curcumae 10, Radix Glycyrrhizae 10, Radix Clematidis 10, Fel Ursi 5, Folium Pyrrosiae 30, Radix Et Rhizoma Rhei 20, Natrii Sulfas 10, Fructus Crataegi 15, Radix Bupleuri 6, Rhizoma Chuanxiong 20, Fructus Jujubae 10.

Embodiment 3: with following raw material of Chinese medicine through screening, clean and pulverize, add water and make oral concentrated solution and promptly become preparation of the present invention.

Herba Lysimachiae 100, Herba Artemisiae Scopariae 9, Endothelium Corneum Gigeriae Galli 16, Fructus Aurantii 8, Radix Salviae Miltiorrhizae 18, Pericarpium Citri Reticulatae 18, Rhizoma Cyperi 8, Radix Curcumae 21, Radix Glycyrrhizae 7, Radix Clematidis 30, Fel Ursi 12, Folium Pyrrosiae 21, Radix Et Rhizoma Rhei 16, Natrii Sulfas 13, Fructus Crataegi 12, Radix Bupleuri 8, Rhizoma Chuanxiong 15, Fructus Jujubae 15.

The Jindan gallbladder stone dissolving capsule treatment cholelithiasis 120 routine clinical reports of the present invention of utilizing the foregoing description to make are as follows:

One, clinical data

1, the patient that 120 routine patients treated for special outpatient clinic is organized in treatment, male's 52 examples, women's 68 examples, age 25-50 year 72 examples, patient's 48 examples more than 50 years old, non-evident sympton or only show general dyspepsia person's 96 examples usually has stomachache, feels sick, symptom 24 people such as vomiting, and all patients are all through ultrasound diagnosis more than 2 times or remake X line, CT, gallbladder examination and make a definite diagnosis.

2, two groups of sexes of patient of making a definite diagnosis from the treatment group of matched group 102 patients, age, the course of disease, the state of an illness, cardinal symptom, professional aspect there was no significant difference relatively has comparability.

Two, Therapeutic Method

1, treatment group: according to actual capsule or the pill made of patient, medication dose is grasped flexibly according to patient age, body constitution by prescription of the present invention, every day three times, one after each meal 6 grams.30 days is a course of treatment, and be an observation period three courses of treatment.

2, treatment group: take German AIHUO DANTONG every day, every day 3 times, one time 2.

Three, therapeutic effect

1, criterion standard: adopt the whole nation unified diagnosis and curative effect judging standard.

Cure: sings and symptoms disappears, and imaging examination (B ultrasonic, PTC, ERCP, biliary tract vein or peroral contrast must have wherein 2 kinds of inspection methods) calculus disappears; Produce effects: sings and symptoms alleviates, and the imaging examination calculus has obviously and reduces, reach more than 1/2, or the calculus person of diminishing; Invalid: symptom and body no change, the imaging examination calculus does not have the changer.

2, two groups of total effectses relatively treatment organize 120 examples, cure 81 (accounting for 67.50%), produce effects 33 examples (accounting for 27.5%), invalid 6 examples (accounting for 5%), total effective rate reaches 95%; Matched group 102 examples are cured 15 examples (accounting for 14.71%), produce effects 36 examples (accounting for 35.29%), invalid 51 examples (accounting for 50.00%), total effective rate 50%.Two groups of cure rate differences have significance (ρ＜0.05=.

Four, brief summary

1, clinical observation result shows, the Jindan gallbladder stone dissolving capsule total effective rate is 95%, and cure rate is 67.50%, evident in efficacy, obviously be better than matched group medicine Germany DANTONG.

2, Jindan gallbladder stone dissolving capsule is formed with Chinese herbal medicine, mineral and animal raw materials, have depressed liver-energy dispersing and QI regulating, anti-inflammatory and choleretic, spleen invigorating gentle stomach, the stasis of blood of reducing phlegm, melt the effect of liver and bile stone, the full reasonable recipe of visiting, compatibility is proper, thereby cholelithiasis is had therapeutical effect preferably.

Claims (2)

1, a kind of Jindan gallbladder stone dissolving capsule for the treatment of liver and bile stone disease is characterized in that being made by the raw material of following weight portion:

Herba Lysimachiae 6-180, Herba Artemisiae Scopariae 6-15, Endothelium Corneum Gigeriae Galli 10-20, Fructus Aurantii 6-10, Radix Salviae Miltiorrhizae 10-25, Pericarpium Citri Reticulatae 10-25, Rhizoma Cyperi 6-10, Radix Curcumae 10-30, Radix Glycyrrhizae 5-10, Radix Clematidis 10-60, Fel Ursi 5-15, Folium Pyrrosiae 10-30, Radix Et Rhizoma Rhei 10-20, Natrii Sulfas 10-15, Fructus Crataegi 10-15, Radix Bupleuri 6-10, Rhizoma Chuanxiong 10-20, Fructus Jujubae 10-20.

2, Jindan gallbladder stone dissolving capsule according to claim 1 is characterized in that being made by the raw material of following weight portion:

Herba Lysimachiae 50-120, Herba Artemisiae Scopariae 8-12, Endothelium Corneum Gigeriae Galli 13-17, Fructus Aurantii 8-12, Radix Salviae Miltiorrhizae 17-22, Pericarpium Citri Reticulatae 17-22, Rhizoma Cyperi 8-12, Radix Curcumae 18-25, Radix Glycyrrhizae 5-10, Radix Clematidis 30-40, Fel Ursi 5-15, Folium Pyrrosiae 18-25, Radix Et Rhizoma Rhei 15-18, Natrii Sulfas 10-15, Fructus Crataegi 10-15, Radix Bupleuri 6-10, Rhizoma Chuanxiong 15-18, Fructus Jujubae 10-20.