CN1762437A - Bolus for treating rheumatic or rheumatoid arthritis and its preparation method - Google Patents
Bolus for treating rheumatic or rheumatoid arthritis and its preparation method Download PDFInfo
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Abstract
The invention relates to a bolus for treating rheumatic or rheumatoid arthritis and its preparation method, wherein the raw material comprises the following ingredients (by weight ratio): refined semen strychni flour 1-2 parts, buthus martensi kirsch 1 part, centipede 0.75 part, Agkis trodon 1 part, earthworm 1 part, processed radix aconiti 1 part, radic aconiti kusnezoffii preparata 1 part, prepared frankincense 1 part, myrrh 1 part, atractylodes rhizome 1 part, and licorice root 0.5 part.
Description
Technical field
The present invention relates to a kind of medicine pill for the treatment of rheumatism and rheumatoid arthritis and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Rheumatism is a kind of commonly encountered diseases, frequently-occurring disease, easily diagnosis and treatment of acute attack stage, and do not stay sequela.But if mistaken diagnosis or mistake control, will show effect does not repeatedly touchingly more form chronic rheumatism, even merges heart disease, causes great misery to the patient, brings serious burden for family and society.
Rheumatoid disease motherland medical science is referred to as " rheumatism involving the bone severe and migratory arthralgia ", because of pain such as tiger sting, claims severe and migratory arthralgia wind again, all causes because of the wet three evil heterozygosis of wind and cold.Have many scholars to think that rheumatoid is a kind of generalized osteoarthrosis of immunologic hypofunction in recent years, onset is slow, and is out in the cold easily, but the skeleton easy deformation, how thornyly treats, and still can cure if can early find diagnosis and treatment early.Rheumatoid is " catabasis " often to adopt pill in the stabilization sub stage, adheres to taking medicine, and in the hope of slow sick slow controlling, also can receive excellent curative.
Because rheumatism and rheumatoid disease their early stage often can not cause patient's attention, yet the time one is of a specified duration, whenever overcast and rainy or tired overweight, the morbidity joint will aggravate the pain, when serious even swelling is tetanic influences activity, function of joint goes down or loses, and can't take care of oneself, the serious reduction quality of life more can not normally be worked.Rheumatism and rheumatoid disease are a kind of diseases of the people's of having a strong impact on life health, especially in vast rural area, since living condition's relative mistake some, peasant's labor intensity is bigger, health care consciousness is relatively poor, and sickness rate is higher, and medical condition is relatively also weaker, some patient's obstinate, very painful.The medicine of treatment rheumatism and rheumatoid arthritis is a lot, and curative effect differs, and often has repeatedly, and patient seeks medical advice everywhere, and the patient who has cures for a long time that but curative effect is very poor.The present inventor is an old docter of TCM of tcm family, long-term diagnosis and treatment rheumatism patient, on the basis of secret prescription handed down in the family from generation to generation, experience in conjunction with a large amount of patients of its diagnosis and treatment, invent out a kind of pill for the treatment of rheumatism and rheumatoid arthritis disclosed in this invention, it is named as the forced chasing wind pellet of treatment rheumatism and rheumatoid arthritis in actual applications.
Summary of the invention
The objective of the invention is to overcome the deficiencies in the prior art and defective, needs at vast rheumatism and rheumatoid disease patient, a kind of medicine pill for the treatment of rheumatism and rheumatoid arthritis is proposed, this medicine pill can significantly alleviate patient's arthralgia, eliminates swelling, curative effect obviously, low price, the patient that is particularly suitable for vast rural area and low-income group take.The present inventor through prolonged and repeated research, accumulates a large amount of clinical experiences on the basis of old and well-known family's secret prescription handed down in the family from generation to generation, finished the present invention.
For reaching above-mentioned purpose, the present invention proposes a kind of pill for the treatment of rheumatism and rheumatoid arthritis, and the prescription of the parts by weight of raw materials of this pill is:
0.75 part of Agkistrodon of 1 part of Scolopendra of 1～2 part of Scorpio of powder is 1 part before the refining horse
1 part of 1 part of Radix Aconiti Kusnezoffii Preparata of 1 part of Radix Aconiti Preparata of 1 part of Pheretima of Bombyx Batryticatus
0.5 part in 1 portion of Radix Glycyrrhizae of 1 part of Rhizoma Atractylodis of 1 part of Myrrha (processed) of Olibanum (processed)
1 part of 1 part of Rhizoma Chuanxiong of 1 part of Radix Rehmanniae Preparata of 1 part of Radix Angelicae Sinensis of the Radix Paeoniae Alba
The mix powder of raw material adds the pill that 400～600 milliliters 868 concentrated solutions are modulated to 6～10 ball/grams more than each kilogram.
Wherein, the prescription of the parts by weight of raw materials of described 868 concentrated solutions is:
2 parts of 1 portion of Herba Erodiis of 2 parts of Daphne giraldii Nitsche of Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)
1 part of 2 parts of Radix Achyranthis Bidentatae of Radix Salviae Miltiorrhizae
The mixture of five kinds of raw materials adds decocting system, filters, is condensed into 400～600 milliliters concentrated solution more than each kilogram, evenly dissolves 1 part of Colla cornus cervi again, makes 868 concentrated solutions.
Wherein, powder is raw material with the Semen Strychni before the described refining horse, with Semen Strychni boil, remove the peel hair, cut into slices, dry, stir-baking with sand, grinding and make powder before the refining horse.
The present invention also provides a kind of preparation method for the treatment of the pill of rheumatism and rheumatoid arthritis, and the method comprising the steps of:
1) powder before the refining horse of preparation is about to that Semen Strychni boils, removes the peel hair, cuts into slices, dries, stir-baking with sand, grind into powder;
2) the Chinese medicine mixed grinding with following weight portion prescription is the Chinese medicine mixed-powder, 1 part of Scorpio, 0.75 part of Scolopendra, 1 part of Agkistrodon, 1 part of Bombyx Batryticatus, 1 part of Pheretima, 1 part of Radix Aconiti Preparata, 1 part of Radix Aconiti Kusnezoffii Preparata, 1 part of Olibanum (processed), 1 part of Myrrha (processed), 1 part of Rhizoma Atractylodis, 0.5 part in Radix Glycyrrhizae, 1 part of the Radix Paeoniae Alba, 1 part of Radix Angelicae Sinensis, 1 part in Radix Rehmanniae Preparata, 1 part of Rhizoma Chuanxiong;
3) with above-mentioned steps 1) 1～2 part in powder and above-mentioned steps 2 before the refining horse of preparation) the Chinese medicine mixed-powder for preparing is uniformly mixed into standby Chinese medicine mixed-powder;
4) preparation 868 concentrated solutions, concentrated solution is made in the Chinese medicine mixing decoction of following weight portion prescription, 2 parts of Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)s, 1 part of Daphne giraldii Nitsche, 2 parts of Herba Erodiis, 2 parts of Radix Salviae Miltiorrhizaes, 1 part of Radix Achyranthis Bidentatae, the mixture of five kinds of raw materials decocts with water twice more than each kilogram, each amount of water was not advisable to have powder, merge decocting liquid twice, filtration and heating concentrate makes 400～600 milliliters concentrated solution, in this concentrated solution, add 1 part of Colla cornus cervi then while hot, and melt and make it uniform mixing, through natural cooling, make 868 concentrated solutions;
5) the 868 concentrated solutions modulation above-mentioned steps made from above-mentioned step 4) 3) prepared standby Chinese medicine mixed-powder, 868 concentrated solutions that the adding of the standby Chinese medicine mixed-powder of each kilogram raw material is 400～600 milliliters evenly mix, and make the wet pill of 6～10 ball/grams;
6) will wet pill oven dry is the finished product pill, and its baking temperature is 70～75 ℃, and stoving time is 1～3 hour.
Powder is an important component before the refining horse in the parts by weight of raw materials prescription of the pill of above-mentioned treatment rheumatism and rheumatoid arthritis, and be one and contain virose composition, when its share is 1 part, the drug effect of the treatment rheumatism of being made and the pill of rheumatoid arthritis relatively relaxes, generally must take twice in one day, sooner or later respectively once.When its share was 2 parts, the drug effect of the treatment rheumatism of being made and the pill of rheumatoid arthritis was more intense, can only take once in general one day, must take after the supper.The concrete instructions of taking of taking any pill, each pill is fibrous root determining through Visually Inspected patient's age, muscle power and the concrete state of an illness according to the doctor also.
The present invention sums up on the basis of secret prescription handed down in the family from generation to generation the inventor, again in conjunction with my experience of practising medicine for a long time, the present invention who is provided treats pill of rheumatism and rheumatoid arthritis and preparation method thereof and has the following advantages and effect: take this medicine pill by doctor's advice and can significantly alleviate patient's arthralgia, elimination swelling, obvious, the low price of curative effect, the patient who is particularly suitable for vast rural area and low-income group takes, and the special preparation method of this medicine pill makes the curative effect of this pill more obvious.
The specific embodiment
Below by introducing embodiment and case in detail, further specify the specific embodiment of the present invention and effect.
Embodiment 1
The invention provides a kind of pill for the treatment of rheumatism and rheumatoid arthritis, the prescription of the parts by weight of raw materials of this pill is:
0.75 part of Agkistrodon of 1 part of Scolopendra of 1 part of Scorpio of powder is 1 part before the refining horse
1 part of 1 part of Radix Aconiti Kusnezoffii Preparata of 1 part of Radix Aconiti Preparata of 1 part of Pheretima of Bombyx Batryticatus
0.5 part in 1 portion of Radix Glycyrrhizae of 1 part of Rhizoma Atractylodis of 1 part of Myrrha (processed) of Olibanum (processed)
1 part of 1 part of Rhizoma Chuanxiong of 1 part of Radix Rehmanniae Preparata of 1 part of Radix Angelicae Sinensis of the Radix Paeoniae Alba
The mix powder of raw material adds the pill that 400～600 milliliters 868 concentrated solutions are modulated to 8 ball/grams more than each kilogram.
Wherein, the prescription of the parts by weight of raw materials of described 868 concentrated solutions is:
2 parts of 1 portion of Herba Erodiis of 2 parts of Daphne giraldii Nitsche of Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)
1 part of 2 parts of Radix Achyranthis Bidentatae of Radix Salviae Miltiorrhizae
The mixture of five kinds of raw materials adds decocting system, filters, is condensed into 400～600 milliliters concentrated solution more than each kilogram, evenly dissolves 1 part of Colla cornus cervi again, makes 868 concentrated solutions.The present invention with same weight and in the bigger above-mentioned five kinds of raw materials of volume the decocting method of medicinal routine be condensed into concentrated solution, dissolve Colla cornus cervi again, medicinal ingredient is not only arranged, but also has good adhesive effect, can be used as binding agent the mix powder of above-mentioned main medicine material is glued together, make pill.
Wherein, powder is raw material with the Semen Strychni before the described refining horse, with Semen Strychni boil, remove the peel hair, cut into slices, dry, stir-baking with sand, grinding and make powder before the refining horse.
The present invention also provides a kind of preparation method for the treatment of the pill of rheumatism and rheumatoid arthritis, it is characterized in that the method comprising the steps of:
1) powder before the refining horse of preparation is about to that Semen Strychni boils, removes the peel hair, cuts into slices, dries, stir-baking with sand, grind into powder;
2) the Chinese medicine mixed grinding with following weight portion prescription is the Chinese medicine mixed-powder, 1 part of Scorpio, 0.75 part of Scolopendra, 1 part of Agkistrodon, 1 part of Bombyx Batryticatus, 1 part of Pheretima, 1 part of Radix Aconiti Preparata, 1 part of Radix Aconiti Kusnezoffii Preparata, 1 part of Olibanum (processed), 1 part of Myrrha (processed), 1 part of Rhizoma Atractylodis, 0.5 part in Radix Glycyrrhizae, 1 part of the Radix Paeoniae Alba, 1 part of Radix Angelicae Sinensis, 1 part in Radix Rehmanniae Preparata, 1 part of Rhizoma Chuanxiong;
3) with above-mentioned steps 1) 1 part in powder and above-mentioned steps 2 before the refining horse of preparation) the Chinese medicine mixed-powder for preparing is uniformly mixed into standby Chinese medicine mixed-powder;
4) preparation 868 concentrated solutions, concentrated solution is made in the Chinese medicine mixing decoction of following weight portion prescription, 2 parts of Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)s, 1 part of Daphne giraldii Nitsche, 2 parts of Herba Erodiis, 2 parts of Radix Salviae Miltiorrhizaes, 1 part of Radix Achyranthis Bidentatae, the mixture of five kinds of raw materials decocts with water twice more than each kilogram, each amount of water was not advisable to have powder, merge decocting liquid twice, filtration and heating concentrate makes 400～600 milliliters concentrated solution, in this concentrated solution, add 1 part of Colla cornus cervi then while hot, and melt and make it uniform mixing, through natural cooling, make 868 concentrated solutions;
5) the 868 concentrated solutions modulation above-mentioned steps made from above-mentioned step 4) 3) prepared standby Chinese medicine mixed-powder, 868 concentrated solutions that the adding of the standby Chinese medicine mixed-powder of each kilogram raw material is 400～600 milliliters evenly mix, and make the wet pill of 8 ball/grams;
6) will wet pill oven dry is the finished product pill, and its baking temperature is 70～75 ℃, and stoving time is 1～3 hour, and the finished product pill after the oven dry is essentially 10 ball/grams.
Embodiment 2
The treatment rheumatism of present embodiment and pill of rheumatoid arthritis and preparation method thereof are substantially the same manner as Example 1, and the share that is the preceding powder of described refining horse is 2 parts.At preparation method being attacked by dampness pill is 10 ball/grams, and the finished product pill after the oven dry is essentially 12 ball/grams.
Because powder is an important component before the described refining horse, and be one and contain virose composition that when its share was 1 part, the drug effect of the treatment rheumatism of being made and the forced chasing wind pellet of rheumatoid arthritis relatively relaxed, generally must take twice in one day, sooner or later respectively once.When its share was 2 parts, the drug effect of the treatment rheumatism of being made and the forced chasing wind pellet of rheumatoid arthritis was more intense, can only take once in general one day, must take after the supper.Concrete instructions of taking also must be looked patient's the concrete state of an illness and determine.
The inventor once treated a large amount of rheumatism patients and rheumatoid patient with the pill of this treatment rheumatism and rheumatoid arthritis, and curative effect is obvious, and reflection among the people is good.The panel of expert that China Association of Traditional Chinese Medicine forms once in the Yongcheng City, Henan and the surrounding area many cases patient is carried out on-the-spot investigation, in order to further specify beneficial effect of the present invention, describe in detail to pill of the present invention treatment rheumatism and rheumatoid arthritis and through the clinical observation on the therapeutic effect that panel of expert comes to 7 cases of investigation personally more below and (annotate: the pill of powder before the treatment rheumatism of being taken and the pill of rheumatoid arthritis only contain a refining horse in for prescription, if take the pill that contains the preceding powder of two parts of refining horses, then change one day into and take once, must take after the supper).
Investigate purpose: observe the clinical efficacy of the pill of treatment rheumatism and rheumatoid arthritis to rheumatism and rheumatoid arthritis.
Investigation method: the method that adopts own control, perspective study.
The result: the pill of treatment rheumatism and rheumatoid arthritis all has tangible analgesia, detumescence effect to 7 routine rheumatism and rheumatoid arthritis, and the patient is carried out following up a case by regular visits in 2 years, and late result is stable.
Data and the method investigated:
1, case source: Yongcheng City, Henan Province Bai Yang neighbourhood committee spring thatched cottage Rheumatism Dept. outpatient service and entrust the expert of China Association of Traditional Chinese Medicine to observe case totally 7 examples, 24 years old of age minimum, maximum 63 years old, average 52.8 years old; Wherein, male's 1 example, women's 6 examples.Rheumatic arthritis 3 examples, rheumatoid arthritis 4 examples.The course of disease is the longest 36 years, the shortest 1 year.
2, diagnostic criteria: meet the diagnostic criteria that rheumatoid arthritis that Americanism damp disease association 1987 proposes and first national traditional Chinese medical science rheumatism academic conference of diagnostic criteria and China of rheumatic arthritis are revised.
3, observational technique: (1) method of administration: every day 2 times, sooner or later after meal with yellow wine 50 gram or warm water delivery services.Concrete medication dose is decided according to patient's age and maximum tolerance degree.The person was each 15～20 in 10～15 years old, and the person was each 20～30 in 15～20 years old, and the person was each 30～50 in 20～50 years old; Adult physical fitness is obeyed 30 first than the powerhouse, 20 of weak persons.The wherein every increase of patient age 1 years old more than 50 years old reduces 1 every day.When taking medicine by this dosage and method, increase by 1～2 every night at every turn, until being added to till the patient adapts to dosage, promptly take medicine about 2 hours, conscious slight dizziness, extremity are little frightened exhibition for an amount of, can not increase dosage again, and so informal dress is until recovery from illness.(2) course of treatment: 30 days was 1 course of treatment, and general 1～6 course of treatment, chronic rheumatoid class disease need be adhered to 1～2 year.
Investigate institute's accepted standard and result:
1, criterion of therapeutical effect:
The sick efficacy assessment standard of formulating according to Ningbo in 1984 meeting of the sick Professional Committee of numbness of Chinese national tcm internal medicine association of numbness.
Clinical cure: symptom all disappears, and it is normal that functional activity recovers, and the main reference index (erythrocyte sedimentation rate, anti-O, rheumatoid factor. physical and chemical indexs such as blood uric acid) normal.
Produce effects: symptomatology is eliminated or cardinal symptom is eliminated, and function of joint is recovered substantially, can participate in operate as normal and work, and the main reference index is normal substantially.
Take a turn for the better: cardinal symptom is eliminated substantially, and main function of joint is recovered substantially or had obviously progressively, and can't take care of oneself transfers to and taking care of oneself, and perhaps loses the job or work capacity transfers to and working and ability to work is recovered to some extent.
Invalid: and compare before the treatment, each side does not all have progress.
2, result:
(1) clinical cure 4 examples, produce effects 2 examples, invalid 1 example.1 example is invalid to be that the course of disease is longer, reaches 36 years, and the joint gross distortion has been lost viability.
(2) physico-chemical examination is influenced: 3 routine rheumatic arthritis wherein, anti-0 (ASO) (+) before the treatment, treatment back ASO all transfers (-) to; 4 routine rheumatoid arthritiss, rheumatoid factor (+) before the treatment, treatment back 2 examples transfer (-) to.
Erythrocyte sedimentation rate all speeds before all patient treatments, is up to 105mm/h, and 6 routine erythrocyte sedimentation rates are reduced to normally after treating; Generally began in 2 weeks to descend in the back of taking medicine, decline in 1～2 month is apparent in view, recovers normal person's 4 examples; Recovered normal person's 2 examples in 3～6 months.
The shortest 2 months of medicine time, the longest took medicine 2 years.Followed up a case by regular visits to 1 year after withdrawing medicine, recurrence does not all appear in the patient of all alleviations.
List the clinical observation of 7 model cases being investigated below,, further specify the curative effect of the pill of treatment rheumatism and rheumatoid arthritis to make comparisons.
Model case 1
Patient's name: Wang Suying, woman, 57 years old.Town Li Tangfang people from village closed at county town, Yongcheng, Henan Province.
The main suit: whole body arthralgia 3 years, increased the weight of 1 month.
History of present illness: whole body arthralgia appearred in the patient because of suffering from cold in 1999, with finger-joint, two joint of the lower extremity is outstanding, local congestion and swelling pain, the heat that occurs together,, whenever increase the weight of because of Changes in weather, be diagnosed as " rheumatoid arthritis " in the People's Hospital, city, it is surplus February to give the antipyretic analgesic hospitalization, and the state of an illness is alleviated, and recurs after the February of leaving hospital.The state of an illness increased the weight of in nearly 1 month, and whole body arthralgia is attached most importance to extremities joint, and is local red and swollen, and hypnalgia very even can not be fallen asleep companion's low grade fever, inappetence.Seek medical advice and look into rheumatoid factor (+) at that time, anti-O (-), erythrocyte sedimentation rate 105mm/h, give pill treatment of the present invention, begin 30/time, every day 1 time, the preceding warm water delivery service of sleeping, 1 all pain reliefs, increase dosage gradually, increase by 1 every day, to 35/day, when taking medicine beginning slight dizziness is arranged, do not have other untoward reaction.The 2 all backs pain of taking medicine obviously alleviate the laboratory examination in 5 months of taking medicine: rheumatoid factor (+), and anti-O (-), erythrocyte sedimentation rate 60mm/h, arthroncus disappears, pain relief.Adhere to taking medicine 20/time, every day 1 time, keep treatment 1.5 years, the pain complete obiteration.Check after 2 years, rheumatoid factor (-), anti-O (-), erythrocyte sedimentation rate 105mm/h is all normal.
The present invention treats the clinical observation contrast of rheumatoid arthritis
| Physical data | ||||||||
| Name | Wang Suying | Sex | The woman | Age (year) | 57 | |||
| Occupation | The peasant | The native place | Li Tang mill, area just outside a city gate, Yongcheng City, Henan Province | |||||
| The main suit: whole body arthralgia 4 months, increased the weight of 2 months | ||||||||
| History of present illness: whole body arthralgia appears in the patient because of suffering from cold in July, 1999, with finger-joint for very, heat occurs together, lumbago, two joint of the lower extremity swell and ache, at city's examination in hospital, be diagnosed as " rheumatoid arthritis ", give treatments such as antiinflammatory, rheumatism in hospital sb.'s illness took a favorable turn in 2 months to leave hospital.February of leaving hospital is surplus, disease relapse, compound joint pain again, both hands articulations digitorum manus swelling at that time, pain, limitation of activity gives pill treatment of the present invention 2 years, General Symptoms disappears, and it is normal that every index is recovered. | ||||||||
| Before the treatment | After the treatment | |||||||
| Symptom | Check result | Symptom | Check result | |||||
| Whole body arthralgia, two lower limb are for very | ASO (-) | General Symptoms disappears, and it is normal that every index is recovered | ASO (-) | |||||
| RF (+) | RF (+) | |||||||
| ESR105mm/h | ESR60mm/h | |||||||
| ASO (-) | ||||||||
| RF (-) | ||||||||
| ESR10mm/h | ||||||||
Typical case's case history 2
Patient's name: the precious fragrant woman of Korea Spro 46 years old
Unit: the worker of Yongcheng City, Henan Province leather company
Symptom: double knee joint is swollen painful, stretches Qu Buli, the continuous pain in both hands joint, overcast and rainy especially increasing the weight of.Check to be rheumatism through the People's Hospital, city, multi-treatment, unsatisfactory curative effect upon somebody's introduction to spring thatched cottage rheumatism out-patient treatment, is taken pill of the present invention.Beginning secondary every day, each 30 balls increase to 40 balls gradually.Early, yellow wine 50 grams take after the supper.Continue clothes and cause a year and a half, double knee joint, both hands joint recover normal substantially now.
The clinical observation contrast of pill treatment rheumatic arthritis of the present invention
| Physical data | |||||||
| Name | Han Baoxiang | Sex | The woman | Age | 46 years old | ||
| Occupation | The worker | The native place | Yongcheng City leather company | ||||
| The main suit: finger-joint pain is more than 3 years, and the recent months state of an illness increases the weight of gradually | |||||||
| History of present illness: the patient pointed continuous pain in 2000, and heating clothes analgesic agent is effective sometimes, but the time have repeatedly.JIUYUE is checked through the People's Hospital, city, is diagnosed as rheumatism, and double knee joint is swollen painfully to be stretched bent limitedly, once is in hospital repeatedly poor effect. | |||||||
| Before the treatment | After the treatment | ||||||
| Symptom | Check result | Symptom | Check result | ||||
| Both hands refer to, double knee joint swells and ache, the time low grade fever arranged | ASO (+) | Both hands refer to swollen painful the ending that disappear, and two knee joints are detumescence substantially also | ASO (-) | ||||
| RF (+) | RF (+) | ||||||
| ESR75mm/h | ESR15mm/h | ||||||
Typical case's case history 3
Patient's name: Cao Hong cloud woman 27 years old
Unit: western food garden, Yongcheng City, Henan Province
The main suit: whole body arthralgia, nearly ten years whenever overcast and rainy pain increases the weight of.Sometimes heating, through integrative therapy, the time heavy when light, after take pill of the present invention after two months symptom be clearly better, every day secondary, each 30 balls add to 40 balls gradually, sooner or later yellow wine 50 grams take after meal, take pill 6 wheat harvesting periods of the present invention, transference cure, clinical cure.
The clinical observation of pill treatment rheumatic arthritis of the present invention relatively
| Physical data | |||||||
| Name | Cao Hongyun | Sex | The woman | Age | 27 years old | ||
| Occupation | Trade | The native place | Western food garden, first Yongcheng City, Henan | ||||
| The main suit: whole body arthralgia, increased the weight of in nearly two months | |||||||
| History of present illness: the patient suffers from rheumatism in the time of 18 years old, in the warp, western medical treatment, it is heavy when time thes be light, over nearly two months because of cold and high fever, whole body arthralgia increases the weight of, doctor trained in Western medicine transfusion anti-inflammatory treatment, more after soon, the joint is swollen again painful, through taking pill of the present invention subjective symptoms improvement after two months, continued to take pill of the present invention six months, the symptom complete obiteration. | |||||||
| Before the treatment | After the treatment | ||||||
| Symptom | Check result | Symptom | Check result | ||||
| Whole body swollen joint is painful, the time heating arranged | ASO (+) | Transference cure, clinical cure | ASO (-) | ||||
| RF (-) | RF (-) | ||||||
| ESR80mm/h | ESR8mm/h | ||||||
Typical case's case history 4
Patient's name: Qin Yu east man 24 years old
Unit: No. 106, people road, Yongcheng City, Henan Province 6 lane doorplates
The main suit: lumbago and skelalgia 3 years is surplus
History of present illness: the patient in calendar year 2001 because of being affected by the cold, cause lumbago and skelalgia, the beginning mistaken diagnosis is an influenza, after city's examination in hospital is a rheumatic arthritis.Heavy when light when multi-treatment.ASO (+) RF (-) ESR35mm/h through taking pill of the present invention, begins every day twice afterwards to spring thatched cottage Rheumatism Dept. out-patient treatment, and each 30, increase to 50 gradually, to take five months by this amount, the joint is pain no longer, and is clinical complete.
The clinical observation contrast of pill treatment rheumatic arthritis of the present invention
| Physical data | |||||||
| Name | Qin Yudong | Sex | The man | Age | 24 years old | ||
| Occupation | The doctor | The native place | No. 106, people road, Yongcheng City, Henan Province 6 lane doorplates | ||||
| The main suit: lumbago and skelalgia 3 years is surplus | |||||||
| History of present illness: the patient is rheumatism because of waist and leg ache through city's examination in hospital calendar year 2001, through how tame hospitalize, the time heavy when light.Arrived the thatched cottage Rheumatism Dept. out-patient treatment of Yongcheng City spring afterwards, and took pill of the present invention after five months, it is normal to chemically examine every index through city hospital. | |||||||
| Before the treatment | After the treatment | ||||||
| Symptom | Check result | Symptom | Check result | ||||
| The swelling of lumbago lower limb acid knee | ASO (+) | The lumbago and skelalgia clinical cure that disappears substantially | ASO (-) | ||||
| RF (+) | RF (-) | ||||||
| ESR35mm/h | ESR15mm/h | ||||||
Typical case's case history 5
Patient's name: Han Wei man 36 years old
Unit: lake, Luan, Yongcheng City, Henan Province village people
Main suit: waist, gonalgia more than ten years, whenever overcast and rainy swelling and ache increased the weight of, through how tame examination in hospital is rheumatic lumbago and scelalgia, looked into ASO (+) RF (-) ESR60mm/h at that time, afterwards to spring thatched cottage Rheumatism Dept. out-patient treatment, take pill of the present invention, beginning twice of every day, each 40, increase to 50 gradually, one after each meal just significantly alleviated after one month sooner or later, swell and ache after three months and disappear substantially, the patient is in fear of to recur again, takes continuously four months again, and all are normal to check ASO (-) RF (-) ESR6mm/h behind the clinical cure.
The clinical observation contrast of pill treatment rheumatic arthritis of the present invention
| Physical data | |||||||
| Name | Han Wei | Sex | The man | Age | 36 years old | ||
| Occupation | Be engaged in agriculture | The native place | Lake, Luan, Yongcheng City, Henan Province village people | ||||
| The main suit: in year surplus the trouble waist lower limb ten, repeatedly chemical examination is rheumatic arthritis | |||||||
| History of present illness: the patient is frequent pain in the lumbar region in 1993, disappear when time thes be swollen, be diagnosed as rheumatic arthritis through city's examination in hospital at that time, through how tame hospitalize, outbreak repeatedly.Its gonalgia increases the weight of gradually, introduces through others and takes pill of the present invention seven months, existing basic the recovery normally.Overcast and rainy not swollen more painful. | |||||||
| Before the treatment | After the treatment | ||||||
| Symptom | Check result | Symptom | Check result | ||||
| The waist pain, knee joint swells and ache for a long time, and fatigue increases the weight of | ASO (+) | Swollen painful disappearance of knee joint, waist is no longer painful, can work | ASO (-) | ||||
| RF (-) | RF (-) | ||||||
| ESR60mm/h | ESR6mm/h | ||||||
Typical case's case history 6
Patient's name: Liu Feng English woman 49 years old
Unit: Li Tang people from mill, Yongcheng City, Henan Province
The main suit: double knee joint pain some months, whenever overcast and rainy or tired overweight, arthralgia increases the weight of.Through city's examination in hospital is the rheumatic lumbago and skelalgia, the treatment transference cure, and recurrence again after the drug withdrawal, clothes spring thatched cottage, back pill of the present invention begins every day twice, and each 30, be added to 40 gradually, boiled water takes.Obeyed altogether four months, evident in efficacy, pain disappears.
The clinical observation contrast of forced chasing wind pellet treatment rheumatic arthritis
| Physical data | ||||||||
| Name | Liu Fengying | Sex | The woman | Age | 49 years old | |||
| Occupation | Be engaged in agriculture | The native place | Area just outside a city gate town, Yongcheng City, Henan Province Li Tang people from mill | |||||
| The main suit: the double knee joint inflammation swells and ache, and the limitation of activity fatigue increases the weight of | ||||||||
| History of present illness: the swollen painful existing some months of two knee joints and joint, when overcast and rainy work, increase the weight of, limitation of activity is rheumatism through looking into. | ||||||||
| Before the treatment | After the treatment | |||||||
| Symptom | Check result | Symptom | Check result | |||||
| Two swelling and pain in knee tiredly increase the weight of limitation of activity when overcast and rainy | ASO (+) | The disappearance of swelling and ache, symptom takes a turn for the better, and can work | ASO (-) | |||||
| RF (-) | RF (-) | |||||||
| ESR90mm/h | ESR16mm/h | |||||||
Typical case's case history 7
Super male 29 years old of patient's name: Wang Yan
Unit: Yongcheng City, Henan Province king collects the village people
The main suit: two swelling and pain in knee, stretch Qu Buli, the time heating arranged.
History of present illness:, the patient weighed the both legs wheat harvesting period of being in hospital wounded because of traffic accident before half a year, recover normal, March is because of two unexpected swelling of knee joint, through city's hospital orthopedics inspection is rheumatic arthritis, ASO (+) RF (-) ESR75mm/h is spring thatched cottage Rheumatism Dept. out-patient treatment afterwards, take pill of the present invention, begin every day twice, each 30, increase to 40 gradually, sooner or later yellow wine takes after meal, and beginning pain increases the weight of, and enjoins the patient not want drug withdrawal, after adhering to one month, double knee joint is clearly better, and continues to take the disappearance of swelling and ache after six months, clinical cure.
The clinical observation contrast of forced chasing wind pellet treatment rheumatic arthritis
| Physical data | |||||||
| Name | Wang Yanchao | Sex | The man | Age | 29 years old | ||
| The occupation main suit: both legs are original to be weighed wounded, the two unexpected swelling of knee joint of recent months.Control. | The history of present illness of being engaged in agriculture: before the treatment | Native place patient Wang Yanchao before half a year because of traffic accident weighs both legs month surplus being discharged from hospital after recovery of being in hospital wounded, March because of two the treatment after | Yongcheng City, Henan Province king collect village people's lower limb suddenly swollen painful be rheumatic arthritis through city's hospital orthopedics inspection.Symptom is examined in the thatched cottage rheumatism outpatient service of next spring | ||||
| The knee joint swelling as a result of check result symptom checking, | |||||||
| ASO (+) | |||||||
| The knee joint disappearance of swelling and ache, | ASO (-) | ||||||
| Heating is pressed painful | RF (-) | ||||||
| Do not generate heat, can the work name | RF (-) | ESR75mm/h Wang Yan is super | |||||
| ESR18mm/h | Physical data | ||||||
Clinical research observation shows, the pill that the present invention treats rheumatism and rheumatoid arthritis has significantly and eases the pain the detumescence effect, and pain more, and analgesic effect better, and is and rapid-action, low price, the patient who is fit to vast rural area and low-income group uses.The most of patient's pain relief in 1 month of generally taking medicine, the person of being in a bad way takes medicine and can alleviate fully in 2-3 month, has after individual patient is taken medicine slight dizziness, the xerostomia, does not have other untoward reaction.
Although do not find serious toxic and side effects in clinical observation, this medical instrument has significant individual variation, and consumption will be from low dose, and order is progressive, increases dosage gradually.Secondly, this medicine has certain toxicity, must strictness grasp indication under doctor's guidance, and anemia of pregnant woman, hypertension, heart disease, hepatic and kidney function obstacle person avoid usefulness.
Claims (4)
1. a pill for the treatment of rheumatism and rheumatoid arthritis is characterized in that, the prescription of the parts by weight of raw materials of this pill is:
0.75 part of Agkistrodon of 1 part of Scolopendra of 1～2 part of Scorpio of powder is 1 part before the refining horse
1 part of 1 part of Radix Aconiti Kusnezoffii Preparata of 1 part of Radix Aconiti Preparata of 1 part of Pheretima of Bombyx Batryticatus
0.5 part in 1 portion of Radix Glycyrrhizae of 1 part of Rhizoma Atractylodis of 1 part of Myrrha (processed) of Olibanum (processed)
1 part of 1 part of Rhizoma Chuanxiong of 1 part of Radix Rehmanniae Preparata of 1 part of Radix Angelicae Sinensis of the Radix Paeoniae Alba
The mix powder of raw material adds the pill that 400～600 milliliters 868 concentrated solutions are modulated to 6～10 ball/grams more than each kilogram.
2. the pill of described treatment rheumatism according to claim 1 and rheumatoid arthritis, wherein, the prescription of the parts by weight of raw materials of described 868 concentrated solutions is:
2 parts of 1 portion of Herba Erodiis of 2 parts of Daphne giraldii Nitsche of Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)
1 part of 2 parts of Radix Achyranthis Bidentatae of Radix Salviae Miltiorrhizae
The mixture of five kinds of raw materials adds decocting system, filters, is condensed into 400～600 milliliters concentrated solution more than each kilogram, evenly dissolves 1 part of Colla cornus cervi again, makes 868 concentrated solutions.
3. the pill of described treatment rheumatism according to claim 1 and rheumatoid arthritis, wherein, powder is raw material with the Semen Strychni before the described refining horse, with Semen Strychni boil, remove the peel hair, cut into slices, dry, stir-baking with sand, grinding and make powder before the refining horse.
4. preparation method for the treatment of the pill of rheumatism and rheumatoid arthritis is characterized in that the method comprising the steps of:
1) powder before the refining horse of preparation is about to that Semen Strychni boils, removes the peel hair, cuts into slices, dries, stir-baking with sand, grind into powder;
2) the Chinese medicine mixed grinding with following weight portion prescription is the Chinese medicine mixed-powder, 1 part of Scorpio, 0.75 part of Scolopendra, 1 part of Agkistrodon, 1 part of Bombyx Batryticatus, 1 part of Pheretima, 1 part of Radix Aconiti Preparata, 1 part of Radix Aconiti Kusnezoffii Preparata, 1 part of Olibanum (processed), 1 part of Myrrha (processed), 1 part of Rhizoma Atractylodis, 0.5 part in Radix Glycyrrhizae, 1 part of the Radix Paeoniae Alba, 1 part of Radix Angelicae Sinensis, 1 part in Radix Rehmanniae Preparata, 1 part of Rhizoma Chuanxiong;
3) with above-mentioned steps 1) 1～2 part in powder and above-mentioned steps 2 before the refining horse of preparation) the Chinese medicine mixed-powder for preparing is uniformly mixed into standby Chinese medicine mixed-powder;
4) preparation 868 concentrated solutions, concentrated solution is made in the Chinese medicine mixing decoction of following weight portion prescription, 2 parts of Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)s, 1 part of Daphne giraldii Nitsche, 2 parts of Herba Erodiis, 2 parts of Radix Salviae Miltiorrhizaes, 1 part of Radix Achyranthis Bidentatae, the mixture of five kinds of raw materials decocts with water twice more than each kilogram, each amount of water was not advisable to have powder, merge decocting liquid twice, filtration and heating concentrate makes 400～600 milliliters concentrated solution, in this concentrated solution, add 1 part of Colla cornus cervi then while hot, and melt and make it uniform mixing, through natural cooling, make 868 concentrated solutions;
5) the 868 concentrated solutions modulation above-mentioned steps made from above-mentioned step 4) 3) prepared standby Chinese medicine mixed-powder, 868 concentrated solutions that the adding of the standby Chinese medicine mixed-powder of each kilogram raw material is 400～600 milliliters evenly mix, and make the wet pill of 6～10 ball/grams;
6) will wet pill oven dry is the finished product pill, and its baking temperature is 70～75 ℃, and stoving time is 1～3 hour.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005101133571A CN100441208C (en) | 2005-09-28 | 2005-09-28 | Bolus for treating rheumatic or rheumatoid arthritis and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005101133571A CN100441208C (en) | 2005-09-28 | 2005-09-28 | Bolus for treating rheumatic or rheumatoid arthritis and its preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1762437A true CN1762437A (en) | 2006-04-26 |
| CN100441208C CN100441208C (en) | 2008-12-10 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005101133571A Expired - Fee Related CN100441208C (en) | 2005-09-28 | 2005-09-28 | Bolus for treating rheumatic or rheumatoid arthritis and its preparation method |
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| Country | Link |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102078443B (en) * | 2009-12-01 | 2013-04-17 | 天津药物研究院 | Medicine composition, application and preparation thereof |
| CN103394055A (en) * | 2013-07-19 | 2013-11-20 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicine containing nux vomica powder and preparation method thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1124156C (en) * | 1999-03-16 | 2003-10-15 | 丁尚达 | Chinese-medicinal pills for treating rheumatism and preparing process thereof |
| CN1236803C (en) * | 2002-03-20 | 2006-01-18 | 郑国芃 | Rheuamtism treating Chinese medicine |
-
2005
- 2005-09-28 CN CNB2005101133571A patent/CN100441208C/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102078443B (en) * | 2009-12-01 | 2013-04-17 | 天津药物研究院 | Medicine composition, application and preparation thereof |
| CN103394055A (en) * | 2013-07-19 | 2013-11-20 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicine containing nux vomica powder and preparation method thereof |
| CN103394055B (en) * | 2013-07-19 | 2014-12-17 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicine containing nux vomica powder and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN100441208C (en) | 2008-12-10 |
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