CN1743232A - Intermittent rotary non-PVC large infusion soft-bag solid drug filling machine - Google Patents

Intermittent rotary non-PVC large infusion soft-bag solid drug filling machine Download PDF

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Publication number
CN1743232A
CN1743232A CN 200510032053 CN200510032053A CN1743232A CN 1743232 A CN1743232 A CN 1743232A CN 200510032053 CN200510032053 CN 200510032053 CN 200510032053 A CN200510032053 A CN 200510032053A CN 1743232 A CN1743232 A CN 1743232A
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China
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cylinder
bag
nitrogen
links
fill
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CN 200510032053
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CN100491205C (en
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刘祥华
刘燕
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Hunan China Sun Pharmaceutical Machinery Co Ltd
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Hunan China Sun Pharmaceutical Machinery Co Ltd
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Priority to CNB2005100320532A priority Critical patent/CN100491205C/en
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Abstract

The solid medicine filling machine comprises power drive component, central dial, take-in and take-out component, bag-cutting part, part for filling clean air, part for filling nitrogen, thermal sealing part, rack and electric control cabinet. The parts above are set on the side of the center dial that connects with the power drive component and are supported by the rack to layout in turn. Around the central dial is fitted with a bag holder for hanging infusion bag.

Description

The solid drug filling machine of intermittent rotary non-PVC large infusion soft-bag
Technical field
The present invention relates generally to field of pharmaceutical machinery, is specifically related to the filling apparatus that a kind of solid-liquid body medicine is in solid medicine (pulvis) in the non-PVC large infusion soft-bag of different chamber in the same bag respectively.
Background technology
In the prior art, infusing medicine and solid medicine (pulvis) adopt different vessels packing and independent pattern of producing.Because of therapeutic fixed drug (pulvis) with can not long preservation after the assisted solution of injection mixes, and solid medicine (pulvis) easily moisture absorption become tide, so the employing glass bottle is packed separately; Needing to extract a little soup from the infusing medicine container earlier with syringe in use is injected into solid medicine (pulvis) container, shake solid medicine (pulvis) container then, allow solid medicine (pulvis) be dissolved in soup, use the soup in syringe holder solid medicine (pulvis) container to extract out again, be injected in the infusing medicine container, can use after shaking up, so there are the following problems:
1. two kinds of medicine Different Package are used and the productive costs height.
2. time of compounding is long.
3. the process of making up a prescription is prone to error.
4. the mixing the dosing process and need repeatedly carry out of infusing medicine and solid medicine (pulvis), the chance that medicine is polluted increases.
At present, in medicine and pharmaceutical equipment industry, existing production technology can't accomplish that solid-liquid body medicine is in the two chambers of same container or the packaged form of multicell respectively, also the solid medicine filling apparatus of PVC big soft infusion bag nothing but.
Summary of the invention
Technical matters to be solved by this invention is the defective that overcomes above-mentioned prior art, a kind of accurate positioning is provided, compact conformation, productive costs is low, floor area is little, can reduce labor intensity of operating staff, reduces the wasting of resources, the production efficiency height can be finished the can of solid drugs (pulvis) and the solid drug filling machine of the intermittent rotary non-PVC large infusion soft-bag that seals to can injection solution and sealing and the two chambers after sterilization or multi-chamber non PVC large transfusion soft bag.This solid drug filling machine can make solid medicine and liquid medicine be loaded in the different coyote holes in the same bag, has reduced packing container, has reduced the intermediate link of making up a prescription in using, when first aid, saved rescue time especially, reduce use cost, reduce labor intensity, avoid secondary pollution and GMP compatible.
For solving the problems of the technologies described above, the present invention adopts following technical proposals.
A kind of solid drug filling machine of intermittent rotary non-PVC large infusion soft-bag, it is characterized in that: it comprises power-transmitting part and central turnplate, advance bag and output parts, cut bag parts, fill clean dried gas parts more than one or one, can or fill nitrogen and filling parts, heat bond sealing component, rack unit and electric cabinet, describedly advance bag and output parts, cut bag parts, fill clean dried gas parts, can or fill nitrogen and filling parts and heat bond sealing component all is arranged at power-transmitting part links to each other central turnplate by, and support by rack unit, be arranged in order and form bag station, cut a bag station, fill clean dried gas station, fill nitrogen and can station, heat sealing station and output station, the periphery of described central turnplate is equiped with the sackholder that mounts infusion bag.
As a further improvement on the present invention, the described bag parts of cutting comprise and are installed on the clamping part cut on bag fixed support and cut a bag part, described clamping part comprises left clamping plate, right clamping plate and clamps cylinder, left and right symmetrically arranged two piston rods that clamp cylinder link to each other with right clamping plate with the left clamping plate that are oppositely arranged respectively, and the clamping cylinder is fixed in by the clamping cylinder mounting plate to be cut on bag fixed support; The described bag part of cutting comprises cutting knife, traverse feed cylinder and long feed cylinder, cutting knife links to each other with the piston rod of traverse feed cylinder, the traverse feed cylinder is fixed on the slide block of long feed cylinder, and the long feed cylinder is fixed in by the long feed air cylinder fixed plate to be cut on bag fixed support.
Further improve as of the present invention, described can or fill nitrogen and filling parts comprise with can fill that the nitrogen bearing links to each other draw back bag opening part, the powder feeding partial sum fills nitrogen and quantitative filling part; Described sack draws back the below that part is filled nitrogen and quantitative filling part, comprise that the can vacuum cup, the can that are symmetrical set draw back cylinder and the can cylinder of giving up the throne, the can vacuum cup links to each other with the piston rod that cylinder is drawn back in can, can is drawn back the give up the throne piston rod of cylinder of cylinder and can and is linked to each other, and the can cylinder of giving up the throne fills the nitrogen bearing with can and links to each other by the can cylinder mounting plate of giving up the throne; Described powder feeding partly comprises powder conveying mechanism and the powder bucket that links to each other with the powder conveying mechanism; Filling nitrogen and quantitative filling partly comprises stirring drive sleeve, the packing screw drive axle that links to each other with the packing servomotor that links to each other with the stirring miniature motor and fills nitrogen and fill head, described packing screw drive axle sleeve is in stirring drive sleeve, the lower end of stirring drive sleeve is equiped with the mixing device that places in the powder bucket, the lower end installing of packing screw drive axle divides loading screw, divides loading screw to place powder bucket lower end to set in the powder muzzle pipe; But oscilaltion fill nitrogen and fill head is placed in down outside the powder muzzle pipe.
Described filling on nitrogen and the fill head can be provided with nitrogen inlet, can give the indoor nitrogen deoxygenation that fills of solid medicine.
As another improvement of the present invention, described powder conveying mechanism comprises powder feeding miniature motor and powder feeding screw, the powder feeding miniature motor is fixed in can by powder feeding motor link span and fills on the nitrogen bearing, the output shaft of powder feeding miniature motor links to each other with powder feeding screw, powder feeding screw places in the powder feeding screw urceolus, an end that joins with the output shaft of powder feeding miniature motor is by the screw-bearing seat supports, powder inlet on the other end and the powder bucket joins, the screw shaft bearing links to each other with powder feeding motor link span, the powder feeding screw urceolus links to each other with the screw shaft bearing with the powder bucket respectively, and its upper end is provided with hopper; The top of described powder bucket is provided with the shaft bearing, and described stirring drive sleeve is installed in the shaft bearing by bearing, and the upper end of stirring drive sleeve links to each other with the stirring miniature motor by stirring transmission device; Described minute loading screw turning cylinder is loaded on by bearing carrier ring and stirs in the drive sleeve, this minute, the upper end of loading screw turning cylinder linked to each other with the output shaft of packing servomotor, described powder muzzle pipe outer fill nitrogen and the fill head of being placed in down filled the nitrogen support plate with can and linked to each other, can is filled the nitrogen support plate and is filled the nitrogen elevating bracket with a can and link to each other, can is filled on the nitrogen elevating bracket set can and is filled the nitrogen lifting guide pillar and be placed in can and fill on the nitrogen bearing set can and fill in the nitrogen lifting guide pin bushing, can is filled the nitrogen lift cylinder and is installed in can and fills on the nitrogen bearing, and its piston rod fills the nitrogen elevating bracket with can and links to each other; In the powder bucket, be provided with near detector switch.
The described clean dried gas parts that fill comprise that the sack that is installed on the lifting support draws back the partial sum injection section; Described sack draws back part and comprises the vacuum cup that is symmetrical set, draws back cylinder and the cylinder of giving up the throne, vacuum cup links to each other with the piston rod that draws back cylinder, draw back cylinder and link to each other with the cylinder piston rod of giving up the throne, the cylinder of giving up the throne links to each other with lifting support by the cylinder mounting plate of giving up the throne; Described injection section comprises the inflation jet pipe that is installed on the inflation support plate, the inflation support plate links to each other with elevating bracket, is equiped with the lifting guide pin bushing on lifting support, and set lifting guide pillar is placed in the lifting guide pin bushing on the elevating bracket, lift cylinder is installed on the lifting support, and its piston rod links to each other with elevating bracket.
Described heat bond sealing component comprises heat seal cylinder, heat-seal mould and heating plate, two heat seal cylinders are oppositely arranged, all be installed on the heat seal support, the piston rod of heat seal cylinder links to each other with the heating plate that is provided with heating pipe by cleading, heat-seal mould is made up of two blocks of heat-seal mould plates that are oppositely arranged, two blocks of heat-seal mould plates link to each other with heating plate respectively, are connected with temperature-sensing probe on the described heating plate.
Described sackholder is by sackholder moving clamping plate, sackholder strap and can drive the push rod that the moving clamping plate of sackholder move and form, and elastic element is housed on the push rod; Describedly advance bag and the output parts are divided into into bag partial sum output part, describedly advance bag loose gas enclosure cylinder that advances that the bag part comprises the promoted push rod that links to each other with fixed support, described output partly comprises the output pine gas enclosure cylinder of the promoted push rod that links to each other with fixed support, advances loose gas enclosure cylinder of bag and output pine gas enclosure cylinder and is oppositely arranged with the push rod of corresponding sackholder respectively.
Described power-transmitting part comprises power and indexing separator, and power links to each other with indexing separator by transmission device, and indexing separator is fixed on the platen that places the rack unit upper end, and central turnplate links to each other with the output shaft of indexing separator.
Transmission device between described power and the indexing separator is a chain-driving, and described stirring transmission device is a chain-driving.
The invention has the advantages that:
1, the present invention is used for the solid drug filling machine of two chambers/multicell infusion bag, be to the good transfusion solution of can and through two chambers of the non-PVC large infusion after the sterilization or multi-chamber-bag, the interior equipment of different chamber that solid medicine (pulvis) is filled to this sack is provided, having changed solid (pulvis) class medicine can only be with glass bottle packaging and the mode of packing respectively with the transfusion solution of the usefulness of making up a prescription, reduced packing container, production and use cost have been saved, changed the existing dispensing method in hospital's use, reduced the intermediate link of making up a prescription in using, when first aid, saved rescue time especially, alleviate labour intensity, and avoided occurring in the use the contaminated possibility of medicine.
2, the present invention according to the characteristic of easily moisture absorption of solid medicine (pulvis), oxidation deterioration, has used and has filled the clean dried air dry, fills nitrogen deoxygenation operation before can, has improved the quality and the storage time of medicine.
3, the present invention adopts servomotor control and regulates and divide the loading screw can in filling parts, makes and has reduced the waste of solid medicine by the filling accuracy height, also meets the requirement of GMP fully.The total process of can adopt intelligent electromechanical control, degree of automation height.
The present invention will advance bag, will cut bag, fills clean dried gas, fills nitrogen, can, seal with output and all be installed in by the same central turnplate, finish into bag, cut bag, fill clean dried gas, fill nitrogen, can, seal and multiple action such as output, its accurate positioning, compact conformation, floor area is little, and productive costs is low, can reduce operating personal and labour intensity thereof, reduce the wasting of resources, production efficiency is higher.Because solid medicine (pulvis) can is to belong to aseptic packaging, thus two chambers of solid-liquid or multicell big infusion soft bag in solid medicine (pulvis) can, seal and need be arranged on hundred grades of laminar regions in the process, adopt the present invention can reduce the area of hundred grades of laminar regions, cost-cutting.
Description of drawings
Fig. 1 is the structural representation front view of the embodiment of the invention;
Fig. 2 is the structural representation birds-eye view of the embodiment of the invention;
Fig. 3 is the drive disk assembly structural representation of the embodiment of the invention;
Fig. 4 is for advancing the structural representation front view of bag and output parts in the embodiment of the invention;
Fig. 5 is for advancing the structural representation birds-eye view of bag and output parts in the embodiment of the invention;
Fig. 6 is for cutting the structural representation front view of bag parts in the embodiment of the invention;
Fig. 7 is for cutting the structural representation birds-eye view of bag parts in the embodiment of the invention;
Fig. 8 is for filling the structural representation front view of clean dried gas parts in the embodiment of the invention;
Fig. 9 is for filling the structural representation right elevation of clean dried gas parts in the embodiment of the invention;
Figure 10 is for can in the embodiment of the invention or fill nitrogen and the structural representation front view of filling parts;
Figure 11 is for can in the embodiment of the invention or fill nitrogen and the structural representation right elevation of filling parts;
Figure 12 is the structural representation of heat bond sealing component in the embodiment of the invention;
Structural representation when a kind of double-chamber transfusion bag bag that Figure 13 produces for the present invention is shaped;
A kind of double-chamber transfusion bag that Figure 14 produces for the present invention is the structural representation behind the filling liquid medicine;
A kind of double-chamber transfusion bag can solid medicine that Figure 15 the present invention produces and seal after structural representation.
Each label is represented among the figure
1, advances bag and output parts 1-1, advance a bag part
1-2, output part 2, cut bag parts
3, fill clean dried gas parts 4, can or fill nitrogen and filling parts
5, heat bond sealing component
7, electric cabinet 8, rack unit
9, central turnplate 10, platen
11, indexing separator 12, transmission device
13, power 14, bag
15, sackholder 15-1, the moving clamping plate of sackholder
15-2, sackholder strap 15-3, push rod
15-4, elastic element 15-5, push rod connecting panel
16, output pine gas enclosure cylinder 17, advance the loose gas enclosure cylinder of bag
18, fixed support
19, loose gas enclosure cylinder adapter plate 20, cut a bag fixed support
21, long feed air cylinder fixed plate 22, long feed cylinder
23, traverse feed cylinder 24, clamping cylinder mounting plate
25, cutting knife 26, right clamping plate
27, left clamping plate 28, clamping cylinder
29, lifting support 30, the cylinder mounting plate of giving up the throne
31, inflation support plate 32, elevating bracket
33, lifting guide pillar 34, lift cylinder
35, lifting guide pin bushing 36, linear bearing
37, inflation jet pipe 38, the cylinder of giving up the throne
39, draw back cylinder 40, sucker adapter plate
41, the nitrogen bearing is filled in vacuum cup 42, can
43, give up the throne cylinder mounting plate 44, can of can fills the nitrogen support plate
45, nitrogen elevating bracket 46 is filled in can, the nitrogen lifting guide pillar is filled in can
47, nitrogen lift cylinder 48 is filled in can, nitrogen lifting guide pin bushing is filled in can
49, nitrogen linear bearing 50, powder feeding miniature motor are filled in can
51, powder feeding screw 52, hopper
53, powder feeding screw urceolus 54, packing servomotor
55, servomotor seat 56, stirring miniature motor
57, stir drive sleeve 58, stirring transmission device
59, stirring motor seat 60, packing screw drive axle
61, near detector switch 62, shaft bearing
63, mixing device 64, powder bucket
65, following powder muzzle pipe 66, branch loading screw
67, fill nitrogen and fill head 67-1, nitrogen inlet
68, give up the throne cylinder 69, can of can draws back cylinder
70, nitrogen sucker adapter plate 71, can vacuum cup are filled in can
72, powder feeding motor link span 73, screw shaft bearing
74, heat seal support 75, heating plate
76, heat-seal mould 77, heating pipe
78, cleading 79, heat seal cylinder
80, temperature-sensing probe 81, solid coyote hole
82, liquid coyote hole 83, perfusion mouth
84, drug interface 85, seal cover cap
86, cut bag line of position 87, folder bag position
The specific embodiment
As Fig. 1, shown in 2, the solid drug filling machine of intermittent rotary non-PVC large infusion soft-bag of the present invention, comprise power-transmitting part and central turnplate 9, advance bag and output parts 1, cut bag parts 2, fill clean dried gas parts 3 more than one or one, can or fill nitrogen and filling parts 4, heat bond sealing component 5, rack unit 8 and electric cabinet 7, advance bag and output parts 1, cut bag parts 2, fill clean dried gas parts 3, can or fill nitrogen and filling parts 4 and heat bond sealing component 5 all to be arranged at the central turnplate 9 that links to each other with power-transmitting part other, and by rack unit 8 supports, be arranged in order and form bag station, cut a bag station, fill clean dried gas station, can or fill nitrogen and the can station, heat sealing station and output station, wherein filling clean dried gas parts 3 and mostly be one to two, is two in this example.Central turnplate 9 peripheries are equiped with the sackholder 15 that mounts infusion bag.Central turnplate 9 can be made as shape from all directions, and sackholder 15 is installed on eight different azimuth of all directions shape central turnplate 9.Present embodiment is two bags of expendable, and each orientation of central turnplate 9 is provided with two sackholders 15.The present invention also can be made as one bag or many bags of expendable.
As shown in Figure 3, power-transmitting part of the present invention, comprise power 13 and indexing separator 11, power 13 links to each other with indexing separator 11 by transmission device 12, transmission device 12 is chain gear in the present embodiment, indexing separator 11 is fixed on the platen 10 that places rack unit 8 upper ends, and central turnplate 9 links to each other by the output shaft of flange with indexing separator 11.The staff is by going up bag 14 by hand to sackholder 15, power 13 (threephase asynchronous machine and drop-gear box) drives the even calibration rotation of indexing separator 11 (accurate cam roller transmission) batch (-type) (at every turn rotating 45 °, 8 equal portions), indexing accuracy height by driving chain, error is little, accurate positioning.Indexing separator 11 will hang over infusion bag on the sackholder 15 by central turnplate 9 and go to successively and cut bag parts 2, fill clean dried gas parts 3, can or fill nitrogen and filling parts 4, heat bond sealing component 5 and advance bag and output parts 1, finish each parts and require the function that realizes, finally finish the filling and sealing process of solid medicine (pulvis) in the two chambers of solid-liquid/multicell big infusion soft bag.
Shown in Fig. 4,5, sackholder 15 is by sackholder moving clamping plate 15-1, sackholder strap 15-2 and can drive the push rod 15-3 that the moving clamping plate 15-1 of sackholder moves and forms, and push rod 15-3 is equipped with elastic element 15-4, relies on elastic force to clamp soft bag 14.Elastic element 15-4 is a spring in this example, the push rod 15-3 of each sackholder 15 can be provided with upper and lower two, the end of push rod 15-3 passes the set axis hole of sackholder strap 15-2 and is connected with the moving clamping plate 15-1 of sackholder, the other end is connected with a push rod connecting panel 15-5, the spring that is placed on the push rod 15-3 places between sackholder strap 15-2 and the push rod connecting panel 15-5, and sackholder strap 15-2 then is fixed on the central turnplate 9.Two sackholders 15 that are in same orientation in the present embodiment are formed one group, and their push rod 15-3 links to each other with same push rod connecting panel 15-5.Advancing bag and output can be by going up bag after the same group of sackholder bag taking, also can be as Fig. 2, shown in 5 by not respectively bag taking and the last bag of sackholder on the same group that is in two orientation, promptly advance bag and output parts 1 and be divided into into bag part 1-1 and output part 1-2, wherein advance bag part 1-1 and comprise that the promoted push rod 15-3's that links to each other with fixed support 18 by loose gas enclosure cylinder adapter plate 19 advances the loose gas enclosure cylinder 17 of bag, output part 1-2 comprises the output pine gas enclosure cylinder 16 of the promoted push rod 15-3 that links to each other with fixed support 18 by loose gas enclosure cylinder adapter plate 19, advances, output pine gas enclosure cylinder 17,16 are oppositely arranged with push rod connecting panel 15-5 respectively; Fixed support 18 is fixed on the platen 10.When last bag and output, promote push rod connecting panel 15-5 by advancing loose gas enclosure cylinder 17 of bag and output pine gas enclosure cylinder 16 respectively, promote the moving clamping plate 15-1 of sackholder by push rod 15-3 and deviate from sackholder strap 15-2, realize the artificial function that goes up bag and bag taking.After last bag, the bag taking, the cylinder return, then the moving clamping plate 15-1 of sackholder also is repositioned under the effect of elasticity gripping power with sackholder strap 15-2 and fits, and can clamp bag 14 in 87 places, folder bag position (seeing Figure 13) of bag 14.
Shown in Fig. 6,7, bag parts 2 of cutting of the present invention comprise and are installed on the cutting part clamping part cut on bag fixed support 20 and cut a bag part, cut bag fixed support 20 and are installed on the platen 10.Clamping part comprises left clamping plate 27, right clamping plate 26 and clamps cylinder 28, left and right symmetrically arranged two piston rods that clamp cylinder 28 link to each other with the left and right clamping plate 27,26 that are oppositely arranged respectively, and clamping cylinder 28 is fixed in by clamping cylinder mounting plate 24 to be cut on bag fixed support 20.Corresponding with two sackholders 15 that same orientation is provided with, the clamping part in this example also is two.Cut the bag part and comprise cutting knife 25, traverse feed cylinder 23 and long feed cylinder 22, cutting knife 25 links to each other with the piston rod of traverse feed cylinder 23, traverse feed cylinder 23 is fixed on the slide block of long feed cylinder 22, and long feed cylinder 22 is fixed in by long feed air cylinder fixed plate 21 to be cut on bag fixed support 20.When bag 14 rotates to the station of cutting bag parts 2 along with central turnplate 9, a left side, right clamping plate 27,26 under the promotion that clamps cylinder 28, relative motion, the position to be cut of bag 14 is clamped, cutting knife 25 arrives Dutch bag position under the promotion of traverse feed cylinder 23, and vertically cut the bag action with the motion of the slide block of length feed cylinder 22 together, (the edge bag line of position 86 of cutting as shown in figure 14 cuts with bag 14 incisions, perfusion mouth 83 is opened), cutting knife 25 is again with the piston rod return of traverse feed cylinder 23, and get back to original position with the slide block of length feed cylinder 22, wait for that the next one cuts a bag process.
Shown in Fig. 8,9, the clean dried gas parts 3 that fill of the present invention comprise that the sack that is installed on the lifting support 29 draws back the partial sum injection section, and lifting support 29 is fixed on the platen 10.Sack draws back part and comprises the vacuum cup 41 that is symmetrical set, draws back cylinder 39 and the cylinder 38 of giving up the throne; Vacuum cup 41 links to each other with the piston rod that draws back cylinder 39 by sucker adapter plate 40, draws back cylinder 39 and links to each other with cylinder 38 piston rods of giving up the throne, and the cylinder 38 of giving up the throne is fixed on the lifting support 29 by the cylinder mounting plate 30 of giving up the throne.Injection section comprises the inflation jet pipe 37 that is installed on the inflation support plate 31, inflation support plate 31 links to each other with elevating bracket 32, on lifting support 29, be equiped with lifting guide pin bushing 35, set lifting guide pillar 33 is placed in the lifting guide pin bushing 35 by linear bearing 36 on the elevating bracket 32, lift cylinder 34 is installed on the lifting support 29, and its piston rod links to each other with elevating bracket 32.When bag 14 rotates to the station that fills clean dried gas parts 3 along with central turnplate 9, vacuum cup 41 draw back cylinder 39, under the common promotion of the cylinder 38 of giving up the throne, do relative motion to bag 14, near bag 14, and under the pull of vacuum effect, hold perfusion mouth 83 positions (seeing Figure 13~15) on 87 next doors, folder bag position, vacuum cup 41 draws back perfusion mouth 83 with drawing back the withdrawal of cylinder 39 piston rods then.Inflation jet pipe 37 can be under lift cylinder 34 promotes, lifting guide pillar 33 is up-and-down movement in being with the lifting guide pin bushing 35 of linear bearing 36, drive inflation jet pipe 37 knee-actions, the inflation jet pipe 37 relative with the solid coyote hole perfusion mouth 83 of bag 14 fills clean dried gas for the solid coyote hole of bag, remove the moisture content in the solid coyote hole, carry out drying and handle.After charging gas, vacuum cup 41 removes pull of vacuum, unclamps bag 14, with drawing back the piston rod withdrawal of cylinder 39 with the cylinder 38 of giving up the throne.
Shown in Figure 10,11, can of the present invention or fill nitrogen and filling parts 4 comprise with can fill that nitrogen bearing 42 links to each other draw back bag opening part, the powder feeding partial sum fills nitrogen and quantitative filling part; Can is filled nitrogen bearing 42 and is installed on the platen 10.Wherein, draw back bag opening part and be positioned at the below of filling nitrogen and quantitative filling part; It comprises that the can vacuum cup 71, the can that are symmetrical set draw back cylinder 69 and the can cylinder 68 of giving up the throne, the piston rod that can vacuum cup 71 draws back cylinder 69 by can sucker adapter plate 70 and can links to each other, can is drawn back the give up the throne piston rod of cylinder 68 of cylinder 69 and can and is linked to each other, and the can cylinder 68 of giving up the throne fills nitrogen bearing 42 with can and links to each other by the can cylinder mounting plate 43 of giving up the throne.Originally the structure that the sack in drawing back bag opening part and filling clean dried gas parts 3 draws back part is identical.Powder feeding partly comprises powder conveying mechanism and the powder bucket 64 that links to each other with the powder conveying mechanism; The powder conveying mechanism comprises powder feeding miniature motor 50 and powder feeding screw 51, powder feeding miniature motor 50 is fixed in can by powder feeding motor link span 72 and fills on the nitrogen bearing 42, the output shaft of powder feeding miniature motor 50 links to each other with powder feeding screw 51, powder feeding screw 51 places in the powder feeding screw urceolus 53, the end that the output shaft of itself and powder feeding miniature motor 50 joins is supported by screw shaft bearing 73, powder inlet on the other end and the powder bucket 64 joins, screw shaft bearing 73 links to each other with powder feeding motor link span 72, powder feeding screw urceolus 53 links to each other with screw shaft bearing 72 with powder bucket 64 respectively, and its upper end is provided with hopper 52.Filling nitrogen and quantitative filling partly comprises stirring drive sleeve 57, the packing screw drive axle 60 that links to each other with packing servomotor 54 that links to each other with stirring miniature motor 56 and fills nitrogen and fill head 67.The top of powder bucket 64 is provided with shaft bearing 62, stirring drive sleeve 57 is installed in the shaft bearing 62 by bearing, the upper end of stirring drive sleeve 57 links to each other with stirring miniature motor 56 by stirring transmission device 58, and stirring transmission device 58 in this example is chain-driving; The upper end of promptly stirring drive sleeve 57 is provided with sprocket wheel, links to each other with set sprocket wheel on the output shaft that stirs miniature motor 56 by chain.The lower end of stirring drive sleeve 57 is equiped with the mixing device 63 that places in the powder bucket 64.Divide loading screw turning cylinder 60 to be loaded on by bearing carrier ring and stir in the drive sleeve 57, both can relatively rotate.This minute, loading screw turning cylinder 60 upper end linked to each other with the output shaft of packing servomotor 54, and the lower end installing divides a loading screw 66, divides loading screw 66 to place meal outlet place, powder bucket 64 lower end to set in the powder muzzle pipe 65; But oscilaltion fill nitrogen and fill head 67 is placed in down outside the powder muzzle pipe 65; When needs fill nitrogen to the solid coyote hole, also can offer nitrogen inlet 67-1 in a side of filling nitrogen and fill head 67, link to each other with nitrogen and can fill the processing of nitrogen deoxygenation, the quality and the storage time of improving medicine the solid coyote hole.Being placed in down powder muzzle pipe 65 outer fill nitrogen and fill head 67 fills nitrogen support plate 44 with can and links to each other, can is filled nitrogen support plate 44 and is filled nitrogen elevating bracket 45 with a can and link to each other, can is filled on the nitrogen elevating bracket 45 set can and is filled nitrogen lifting guide pillar 46 and fill nitrogen linear bearing 49 by can and be placed in can and fill on the nitrogen bearing 42 set can and fill in the nitrogen lifting guide pin bushing 48, can is filled nitrogen lift cylinder 47 and is installed in can and fills on the nitrogen bearing 42, and its piston rod fills nitrogen elevating bracket 45 with can and links to each other.In powder bucket 64, be provided with near detector switch 61.Packing servomotor 54 is fixed on the servomotor seat 55,55 of servomotor seats are installed on the shaft bearing 62, stirring miniature motor 56 is installed on the stirring motor seat 59, stirring motor seat 59 links to each other with shaft bearing 62 again, and shaft bearing 62 is filled nitrogen bearing 42 by connecting panel and can and linked to each other.The working process of these parts is: when bag 14 rotates to this station along with central turnplate 9, can vacuum cup 71 draws back cylinder 69, can in can and gives up the throne under the common promotion of cylinder 68, do relative motion to bag 14, near bag 14, and under the pull of vacuum effect, hold perfusion mouth 83 positions (seeing Figure 14,15), can vacuum cup 71 draws back the withdrawal of cylinder 69 piston rods with can then, and perfusion mouth 83 is drawn back.Fill under 47 promotions of nitrogen lift cylinder in can, can is filled nitrogen lifting guide pillar 46 and is filled the can of nitrogen lifting linear bearing 49 and fill up-and-down movement in the nitrogen lifting guide pin bushing 48 being with can, drive relative with bags 14 solid coyote hole perfusion mouth 83 nitrogen and fill head 67 knee-actions of filling, carry out the solid medicine can.Can at first feed nitrogen and fill nitrogen, begin can after filling nitrogen.And can amount and filling accuracy are regulated and control branch loading screw 66 by packing servomotor 54, and to reach different loading amount requirements, packing servomotor 54 control can amounts are accurately convenient and precision is high, fully GMP compatible; Powder feeding miniature motor 50 by be loaded in the powder bucket 64 near detector switch 61 in good time start and stop, drive powder feeding screw 51 powder feeding start and stop.Stirring miniature motor 56, to drive mixing devices 63 not stalls moving, prevents in the powder bucket 64 that medicinal powder cohere even kill branch loading screw 66.Can have electronics automatic monitoring device among the present invention, will stop the packing operation automatically when foreign matter being arranged in the chance medicinal powder or dividing loading screw 66 to contact with following powder muzzle pipe 65.Mechanical, electrical, gas integral control that these parts can adopt.After can was intact, can vacuum cup 71 removed pull of vacuum, unclamped bag 14, drew back cylinder 69 with the give up the throne piston rod withdrawal of cylinder 68 of can with can.
Bag 14 enters the heat sealing station behind the intact solid medicine of can.As shown in figure 12, heat bond sealing component of the present invention is installed on the platen 10 by heat seal support 74.These parts comprise heat seal cylinder 79, heat-seal mould 76, cleading 78, heating plate 75, heating pipe 77 and temperature-sensing probe 80.Two heat seal cylinders 79 are oppositely arranged, all be installed on the heat seal support 74, the piston rod of heat seal cylinder 79 links to each other with the heating plate 75 that is provided with heating pipe 77 by cleading 78, heat-seal mould 76 is made up of two blocks of heat-seal mould plates that are oppositely arranged, two blocks of heat-seal mould plates are fitted with heating plate 75 respectively, be connected with temperature-sensing probe 80 on the heating plate 75, can indicate the temperature of heating plate 75.Bag 14 rotates to heat bond sealing component 5 with central turnplate 9, the heat-seal mould 76 that has reached design temperature respectively under the promotion of two heat seal cylinders 79 move toward one another the perfusion mouth 83 of bag 14 is carried out heat sealing.Being furnished with the heating plate 75 of heating pipe 77 can regulate and control heating-up temperature according to the solder up effect by temperature controller, to reach optimum efficiency.
Figure 13~15 are a kind of pair of chamber bag of institute of the present invention can.The present invention can be to solid coyote hole 81 can solid (pulvis) medicines of as shown in figure 13 double-chamber transfusion bag 14, Figure 13 is the bag after being shaped, be divided into liquid coyote hole 82 and solid coyote hole 81, separated by weak welded seam between the two, the perfusion mouth 83 that reserve this moment is not opened.Figure 14 shows that liquid coyote hole 82 filling liquid medicine, drug interface 84 is by seal cover cap 85 sealings, and solid coyote hole 81 is outer by the covering of aluminium film, with lucifuge resistance oxygen.Cut among the figure bag line of position 86 indicated be position of cutting bag parts 2 sack of cutting of the present invention, cutting knife 25 from then on position cuts the perfusion mouth 83 of solid coyote hole 81, then fill nitrogen and fill head 67 and can fill nitrogen and can solid medicine solid coyote hole 81, as shown in figure 15, solid (pulvis) medicine pours into from perfusion mouth 83 and perfusion mouth 83 is sealed.

Claims (10)

1, a kind of solid drug filling machine of intermittent rotary non-PVC large infusion soft-bag, it is characterized in that: it comprises power-transmitting part and central turnplate (9), advance bag and output parts (1), cut bag parts (2), fill clean dried gas parts (3) more than one or one, can or fill nitrogen and filling parts (4), heat bond sealing component (5), rack unit (8) and electric cabinet (7), describedly advance bag and output parts (1), cut bag parts (2), fill clean dried gas parts (3), can or fill nitrogen and filling parts (4) and heat bond sealing component (5) all to be arranged at the central turnplate (9) that links to each other with power-transmitting part other, and support by rack unit (8), be arranged in order and form bag station, cut a bag station, fill clean dried gas station, can or fill nitrogen and can station and heat sealing station and output station, the periphery of described central turnplate (9) is equiped with the sackholder (15) that mounts infusion bag.
2, the solid drug filling machine of intermittent rotary non-PVC large infusion soft-bag according to claim 1, it is characterized in that the described bag parts (2) of cutting comprise and are installed on the clamping part cut on bag fixed support (20) and cut a bag part, described clamping part comprises left clamping plate (27), right clamping plate (26) and clamps cylinder (28), left and right symmetrically arranged two piston rods that clamp cylinder (28) link to each other with right clamping plate (26) with the left clamping plate (27) that are oppositely arranged respectively, and clamping cylinder (28) is fixed in by clamping cylinder mounting plate (24) to be cut on bag fixed support (20); The described bag part of cutting comprises cutting knife (25), traverse feed cylinder (23) and long feed cylinder (22), cutting knife (25) links to each other with the piston rod of traverse feed cylinder (23), traverse feed cylinder (23) is fixed on the slide block of long feed cylinder (22), and long feed cylinder (22) is fixed in by long feed air cylinder fixed plate (21) to be cut on bag fixed support (20).
3, the solid drug filling machine of intermittent rotary non-PVC large infusion soft-bag according to claim 2, it is characterized in that described can or fill nitrogen and filling parts (4) comprise with can fill that nitrogen bearing (42) links to each other draw back bag opening part, the powder feeding partial sum fills nitrogen and quantitative filling part; Described sack draws back partly to be positioned at and fills nitrogen and quantitative filling part below, it comprises that the can vacuum cup (71), the can that are symmetrical set draw back cylinder (69) and the can cylinder (68) of giving up the throne, can vacuum cup (71) links to each other with the piston rod that cylinder (69) is drawn back in can, can is drawn back the give up the throne piston rod of cylinder (68) of cylinder (69) and can and is linked to each other, and the can cylinder (68) of giving up the throne fills nitrogen bearing (42) with can and links to each other by the can cylinder mounting plate (43) of giving up the throne; Described powder feeding partly comprises powder conveying mechanism and the powder bucket (64) that links to each other with the powder conveying mechanism; Filling nitrogen and quantitative filling partly comprises stirring drive sleeve (57), the packing screw drive axle (60) that links to each other with packing servomotor (54) that links to each other with stirring miniature motor (56) and fills nitrogen and fill head (67), described packing screw drive axle (60) is placed in and stirs in the drive sleeve (57), the lower end of stirring drive sleeve (57) is equiped with the mixing device (63) that places in the powder bucket (64), the lower end installing of packing screw drive axle (60) divides loading screw (66), divides loading screw (66) to place powder bucket (64) lower end to set in the powder muzzle pipe (65); But oscilaltion fill nitrogen and fill head (67) is placed in down outside the powder muzzle pipe (65).
4, the solid drug filling machine of intermittent rotary non-PVC large infusion soft-bag according to claim 3 is characterized in that describedly filling nitrogen and fill head (67) is provided with nitrogen inlet (67-1).
5, solid drug filling machine according to claim 3 or 4 described intermittent rotary non-PVC large infusion soft-bags, it is characterized in that described powder conveying mechanism comprises powder feeding miniature motor (50) and powder feeding screw (51), powder feeding miniature motor (50) is fixed in can by powder feeding motor link span (72) and fills on the nitrogen bearing (42), the output shaft of powder feeding miniature motor (50) links to each other with powder feeding screw (51), powder feeding screw (51) places in the powder feeding screw urceolus (53), an end that joins with the output shaft of powder feeding miniature motor (50) is supported by screw shaft bearing (73), powder inlet on the other end and the powder bucket (64) joins, screw shaft bearing (73) links to each other with powder feeding motor link span (72), powder feeding screw urceolus (53) links to each other with screw shaft bearing (72) with powder bucket (64) respectively, and its upper end is provided with hopper (52); The top of described powder bucket (64) is provided with shaft bearing (62), described stirring drive sleeve (57) is installed in the shaft bearing (62) by bearing, and the upper end of stirring drive sleeve (57) links to each other with stirring miniature motor (56) by stirring transmission device (58); Described minute the loading screw turning cylinder (60) be loaded on by bearing carrier ring and stir in the drive sleeve (57), the upper end of this minute loading screw turning cylinder (60) links to each other with the output shaft of packing servomotor (54), described powder muzzle pipe (65) outer fill nitrogen and the fill head (67) of being placed in down filled nitrogen support plate (44) with can and linked to each other, can is filled nitrogen support plate (44) and is filled nitrogen elevating bracket (45) with a can and link to each other, can is filled nitrogen elevating bracket (45) and is gone up set can and fill nitrogen lifting guide pillar (46) and be placed in can and fill nitrogen bearing (42) and go up set can and fill in the nitrogen lifting guide pin bushing (48), can is filled nitrogen lift cylinder (47) and is installed in can and fills on the nitrogen bearing (42), and its piston rod fills nitrogen elevating bracket (45) with can and links to each other; In powder bucket (64), be provided with near detector switch (61).
6, according to the solid drug filling machine of the described intermittent rotary non-PVC large infusion soft-bag of arbitrary claim in the claim 1 to 4, it is characterized in that the described clean dried gas parts (3) that fill, comprise that the sack that is installed on the lifting support (29) draws back the partial sum injection section; Described sack draws back part and comprises the vacuum cup (41) that is symmetrical set, draws back cylinder (39) and the cylinder of giving up the throne (38), vacuum cup (41) links to each other with the piston rod that draws back cylinder (39), draw back cylinder (39) and link to each other with the cylinder of giving up the throne (38) piston rod, the cylinder of giving up the throne (38) links to each other with lifting support (29) by the cylinder mounting plate of giving up the throne (30); Described injection section comprises the inflation jet pipe (37) that is installed on the inflation support plate (31), inflation support plate (31) links to each other with elevating bracket (32), on lifting support (29), be equiped with lifting guide pin bushing (35), elevating bracket (32) is gone up set lifting guide pillar (33) and is placed in the lifting guide pin bushing (35), lift cylinder (34) is installed on the lifting support (29), and its piston rod links to each other with elevating bracket (32).
7, the solid drug filling machine of intermittent rotary non-PVC large infusion soft-bag according to claim 6, it is characterized in that described heat bond sealing component (5) comprises heat seal cylinder (79), heat-seal mould (76) and heating plate (75), two heat seal cylinders (79) are oppositely arranged, all be installed on the heat seal support (74), the piston rod of heat seal cylinder (79) links to each other with the heating plate that is provided with heating pipe (77) (75) by cleading (78), heat-seal mould (76) is made up of two blocks of heat-seal mould plates that are oppositely arranged, two blocks of heat-seal mould plates link to each other with heating plate (75) respectively, are connected with temperature-sensing probe (80) on the described heating plate (75).
8, the solid drug filling machine of intermittent rotary non-PVC large infusion soft-bag according to claim 7, it is characterized in that described sackholder (15) by sackholder moving clamping plate (15-1), sackholder strap (15-2) with can drive sackholder and move the mobile push rod (15-3) of clamping plate (15-1) and form, is equipped with elastic element (15-4) on the push rod (15-3); Describedly advance bag and output parts (1) and be divided into into bag part (1-1) and output partly (1-2), describedly advance bag loose gas enclosure cylinder (17) that advances that bag part (1-1) comprises the promoted push rod that links to each other with fixed support (18), described output part (1-2) comprises the output pine gas enclosure cylinder (16) of the promoted push rod that links to each other with fixed support (18), advances the loose gas enclosure cylinder of bag loose gas enclosure cylinder (17) and output (16) and is oppositely arranged with the push rod (15-3) of corresponding sackholder (15) respectively.
9, the solid drug filling machine of intermittent rotary non-PVC large infusion soft-bag according to claim 8, it is characterized in that described power-transmitting part comprises power (13) and indexing separator (11), power (13) links to each other with indexing separator (11) by transmission device (12), indexing separator (11) is fixed on the platen (10) that places rack unit (8) upper end, and central turnplate (9) links to each other with the output shaft of indexing separator (11).
10, the solid drug filling machine of intermittent rotary non-PVC large infusion soft-bag according to claim 9, it is characterized in that the transmission device (12) between described power (13) and the indexing separator (11) is a chain-driving, described stirring transmission device (58) is a chain-driving.
CNB2005100320532A 2005-08-25 2005-08-25 Intermittent rotary non-PVC large infusion soft-bag solid drug filling machine Expired - Fee Related CN100491205C (en)

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CN100422047C (en) * 2006-08-15 2008-10-01 山东新华医疗器械股份有限公司 Charging sealing machine of powder-liquid in two cavity flexible bag
CN100443372C (en) * 2006-04-26 2008-12-17 长沙楚天科技有限公司 Automatic medicine-filling machine
CN102001469A (en) * 2010-10-26 2011-04-06 楚天科技股份有限公司 Filling assembly for large soft infusion bag production line
CN102001466B (en) * 2009-08-31 2012-11-07 上海松川远亿机械设备有限公司 Zippered bag opening device for rotary bag feeding machine
CN103569393A (en) * 2013-10-31 2014-02-12 安徽正远包装科技有限公司 Vertical type packing machine with food preservation function
CN103910321A (en) * 2014-04-15 2014-07-09 湖南科伦制药有限公司 Filling and sealing equipment of bag-body filling type infusion product
CN104843207A (en) * 2015-05-15 2015-08-19 中山伙伴自动化机械有限公司 Multi-column powder metering device
CN106516308A (en) * 2016-12-22 2017-03-22 山东新华医疗器械股份有限公司 Full-automatic tail filling steric filling and sealing machine
CN106516307A (en) * 2016-12-22 2017-03-22 山东新华医疗器械股份有限公司 Full-automatic soft bag sterile filling and sealing machine
CN106892164A (en) * 2017-04-21 2017-06-27 山东新华医疗器械股份有限公司 A kind of powder racking machine
CN106906500A (en) * 2017-04-24 2017-06-30 西安晨宇环境工程有限公司 A kind of automatic brush plating equipment for integrating brush-plating technique and pre-treating technology
CN108688862A (en) * 2018-07-03 2018-10-23 湖南科伦制药有限公司 A kind of powder and liquid double-chamber bag powder packing powder chamber air charging system
CN110171597A (en) * 2016-01-22 2019-08-27 巴克斯特国际公司 For producing the method and machine of sterile solution product bag
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CN100443372C (en) * 2006-04-26 2008-12-17 长沙楚天科技有限公司 Automatic medicine-filling machine
CN100422047C (en) * 2006-08-15 2008-10-01 山东新华医疗器械股份有限公司 Charging sealing machine of powder-liquid in two cavity flexible bag
CN102001466B (en) * 2009-08-31 2012-11-07 上海松川远亿机械设备有限公司 Zippered bag opening device for rotary bag feeding machine
CN102001469A (en) * 2010-10-26 2011-04-06 楚天科技股份有限公司 Filling assembly for large soft infusion bag production line
CN102001469B (en) * 2010-10-26 2012-07-04 楚天科技股份有限公司 Filling assembly for large soft infusion bag production line
CN103569393A (en) * 2013-10-31 2014-02-12 安徽正远包装科技有限公司 Vertical type packing machine with food preservation function
CN103569393B (en) * 2013-10-31 2016-02-10 安徽正远包装科技有限公司 A kind of food fresh keeping upright packing machine
CN103910321A (en) * 2014-04-15 2014-07-09 湖南科伦制药有限公司 Filling and sealing equipment of bag-body filling type infusion product
CN103910321B (en) * 2014-04-15 2016-03-23 湖南科伦制药有限公司 Bag body fill type infusion products potting fixture
CN104843207A (en) * 2015-05-15 2015-08-19 中山伙伴自动化机械有限公司 Multi-column powder metering device
CN110171597A (en) * 2016-01-22 2019-08-27 巴克斯特国际公司 For producing the method and machine of sterile solution product bag
CN106516307A (en) * 2016-12-22 2017-03-22 山东新华医疗器械股份有限公司 Full-automatic soft bag sterile filling and sealing machine
CN106516308A (en) * 2016-12-22 2017-03-22 山东新华医疗器械股份有限公司 Full-automatic tail filling steric filling and sealing machine
CN106892164A (en) * 2017-04-21 2017-06-27 山东新华医疗器械股份有限公司 A kind of powder racking machine
CN106906500A (en) * 2017-04-24 2017-06-30 西安晨宇环境工程有限公司 A kind of automatic brush plating equipment for integrating brush-plating technique and pre-treating technology
CN108688862A (en) * 2018-07-03 2018-10-23 湖南科伦制药有限公司 A kind of powder and liquid double-chamber bag powder packing powder chamber air charging system
CN111532463A (en) * 2020-04-16 2020-08-14 王炳辉 Auxiliary liquid inoculation equipment for strain bags
CN111532463B (en) * 2020-04-16 2021-12-31 上海七感食品有限公司 Auxiliary liquid inoculation equipment for strain bags
CN117645037A (en) * 2024-01-29 2024-03-05 四川省机械研究设计院(集团)有限公司 Material packaging equipment and material packaging method
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