CN1733166A - Chinese traditional medicine preparation for curing gastric ulcer - Google Patents
Chinese traditional medicine preparation for curing gastric ulcer Download PDFInfo
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- CN1733166A CN1733166A CNA2005100179101A CN200510017910A CN1733166A CN 1733166 A CN1733166 A CN 1733166A CN A2005100179101 A CNA2005100179101 A CN A2005100179101A CN 200510017910 A CN200510017910 A CN 200510017910A CN 1733166 A CN1733166 A CN 1733166A
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Abstract
Disclosed is a Chinese medicinal preparation for treating gastric ulcer, which is prepared from dragon's blood resin, licorice root, cuttle-bone, notoginseng and bletilla striata.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine preparation for the treatment of gastric ulcer.
Background technology
Drink raw food vinegar-pepper, have meal irregular or drink after cause that gastric mucosa comes off, form gastric ulcer easily; The main reveal any symptoms of gastric ulcer is: pantothenic acid, have a stomach-ache, on an empty stomach painful, pain etc. after the meal.The medicine of clinical treatment gastric ulcer, many and disorderly, have many drawbacks, as cimetidine, mainly be to reduce gastric acid secretion, also reduce gastric secretion and pepsin output simultaneously, and can promote ulcer healing; But its side effect is bigger, and common have nauseating, constipation, erythra, weak, dizziness etc., accidental thrombocytopenia, granulocytopenia and Liver and kidney toxicity.Sucralfate, antiulcer, its effect mainly is to cover ulcer surface with its adhesion, stops gastric acid and pepsin to continue the invasion and attack ulcer surface, four to eight weeks just can make the small size ulcer healing; Main adverse reaction is constipation.
Summary of the invention
Therefore, still there is demand in the Chinese medicine preparation that people better treat gastric ulcer to curative effect, up to now, also do not find the report of any relevant pharmaceutical composition of the present invention, the inventor is through research repeatedly, finally find the Chinese medicine preparation of the treatment gastric ulcer of better efficacy, thereby finished the present invention.
The purpose of this invention is to provide a kind ofly have no side effect, treating both the principal and secondary aspects of a disease, can more effectively treat the Chinese medicine preparation of gastric ulcer.
The consumption of drug component of the present invention is that the inventor gets through groping in a large number to sum up, and each amounts of components all has curative effect preferably in following weight parts:
Sanguis Draxonis 15-35 part, Radix Glycyrrhizae 5-25 part, Os Sepiae 15-35 part, Radix Notoginseng 10-30 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-25 part.
Medicament selection Sanguis Draxonis of the present invention, Radix Glycyrrhizae, Os Sepiae, Radix Notoginseng, the Pseudobulbus Bletillae (Rhizoma Bletillae) make up, and make each efficacy of drugs produce synergism these drug regimens, thereby effectively treat gastric ulcer; Wherein selecting Sanguis Draxonis, Radix Glycyrrhizae, Os Sepiae, Radix Notoginseng, the Pseudobulbus Bletillae (Rhizoma Bletillae) for use, is because of Sanguis Draxonis, and the Sanguis Draxonis meridian distribution of property and flavor is sweet, salty, flat, GUIXIN, and Liver Channel, function cures mainly, the blood circulation promoting competent silt pain relieving, hemostasis, expelling pus and promoting granulation is used for blood stasis and has a pain, and skin infection does not close up for a long time.Radix Glycyrrhizae, Radix Glycyrrhizae nature and flavor are sweet, warm, GUIXIN, lung, spleen channel, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Os Sepiae, Os Sepiae have another name called Endoconcha Sepiae, and meridian distribution of property and flavor is salty, and is puckery, and tepor is returned liver, kidney channel, and function cures mainly, astringing to arrest bleeding, and relieving leukorrhea by astringents, skin ulcer is held back in antacid, is used for Peptic Ulcers, hyperchlorhydria, hematemesis and epistaxis, stomachache acid regurgitation.Radix Notoginseng, sweet, the little hardship of Radix Notoginseng nature and flavor, temperature are returned liver, kidney channel, dissipating blood stasis hemostasis, subduing swelling and relieving pain.The Pseudobulbus Bletillae (Rhizoma Bletillae), the Pseudobulbus Bletillae (Rhizoma Bletillae), meridian distribution of property and flavor, bitter, sweet puckery, be slightly cold, return lung, liver, the stomach warp, function cures mainly, astringing to arrest bleeding, detumescence and promoting granulation, ulcer haemorrhage.Because the present invention adopts above-mentioned thing to make up, make each efficacy of drugs produce synergism these drug regimens, compared with prior art, the present invention have have no side effect, treating both the principal and secondary aspects of a disease, can more effectively treat the advantage of gastric ulcer.
The specific embodiment
The present invention is made by following bulk drugs: Sanguis Draxonis 15-35 part, Radix Glycyrrhizae 5-25 part, Os Sepiae 15-35 part, Radix Notoginseng 10-30 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-25 part.
The present invention is made by following bulk drugs: Sanguis Draxonis 20-30 part, Radix Glycyrrhizae 10--20 part, Os Sepiae 20-30 part, Radix Notoginseng 15-25 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20 part.
Embodiment 1:
The present invention is made by following bulk drugs: 15 parts of Sanguis Draxonis, 5 parts in Radix Glycyrrhizae, 15 parts of Os Sepiae, 10 parts of Radix Notoginseng, 5 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s.
Embodiment 2:
The present invention is made by following bulk drugs: 20 parts of Sanguis Draxonis, 10 parts in Radix Glycyrrhizae, 20 parts of Os Sepiae, 15 parts of Radix Notoginseng, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s.
Embodiment 3:
The present invention is made by following bulk drugs: 25 parts of Sanguis Draxonis, 15 parts in Radix Glycyrrhizae, 25 parts of Os Sepiae, 20 parts of Radix Notoginseng, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s.
Embodiment 4:
The present invention is made by following bulk drugs: 30 parts of Sanguis Draxonis, 20 parts in Radix Glycyrrhizae, 30 parts of Os Sepiae, 25 parts of Radix Notoginseng, 20 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s.
Embodiment 5:
The present invention is made by following bulk drugs: 35 parts of Sanguis Draxonis, 25 parts in Radix Glycyrrhizae, 35 parts of Os Sepiae, 30 parts of Radix Notoginseng, 25 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s.
The present invention takes by weighing according to the said medicine weight proportion, mixes, and pulverizes, and sieves, and makes capsule according to conventional method.
One, medicine major function of the present invention and therapeutic domain
1, major function:
Treatment stomach pantothenic acid, have a stomach-ache, painful on an empty stomach, pain etc. after the meal
2, therapeutic domain:
Stomach pantothenic acid, have a stomach-ache, on an empty stomach painful, pain etc. after the meal
3, usage and consumption:
Oral every day 3 times, each 3 grams, every capsules 1 gram, 40 minutes ante cibum or warm boiled water are after meal no longer drunk tea after taking medicine, and 10 days is a course of treatment, minimum taking 2 courses of treatment, the longest taking 6 courses of treatment.
Two, the clinical observation of medicine of the present invention
1, physical data
Accept out-patient's 300 examples for medical treatment, the patient is divided into two groups at random, 230 examples are organized in treatment, give Drug therapy of the present invention, and matched group 70 examples have Drug therapy; Minimum 16 years old of age wherein, maximum 76 years old, the longest 25 years the course of disease the shortest half a year, clinical treatment observation, the shortest 2 months, the longest 5 years.51 examples below 40 years old in the treatment group, 40-49 year 103 examples, 50-59 year 52 examples, 26 examples more than 60 years old; The course of disease is 55 examples below 1 year, 2-5 94 examples, 6-10 55 examples, 18 examples more than 10 years; 15 examples below 40 years old in the matched group, 40-49 year 40 examples, 50-59 year 12 examples, 3 examples more than 60 years old; The course of disease is 18 examples below 1 year, 2-5 31 examples, 6--10 16 examples, 5 examples more than 10 years; Two groups of patients are aspect mean age, the course of disease, the state of an illness, and are in a basic balance, have comparability.
2, diagnostic criteria
All case is that diagnosis is determined in diagnostic criteria by the gastric ulcer clinical manifestation all.
Stomach pantothenic acid, have a stomach-ache, on an empty stomach painful, pain etc. after the meal
3, Therapeutic Method
Therapeutic Method is under the voluntary prerequisite of patient, patient is divided into 2 groups at random, and 230 examples are organized in treatment, take medicine of the present invention, each 3 grams, every day 3 times, warm boiled water is no longer drunk tea after taking medicine after meal, 10 days is a course of treatment, minimum taking 2 courses of treatment, the longest taking 6 courses of treatment.Matched group is totally 70 examples, takes existing medicine, each 3 grams, and every day 2-3 time, 10 days is a course of treatment, minimum taking 2 courses of treatment, the longest taking 8 courses of treatment.
4, efficacy assessment standard (being as the criterion) with clinical symptom disappearance
Cure: stomach no longer pantothenic acid, stomach is painful, also painful on an empty stomach, after the meal also pain etc. not; Stomach pantothenic acid, have a stomach-ache, on an empty stomach painful, transference cure such as pain is as the criterion after the meal
Produce effects: stomach no longer pantothenic acid, stomach is slightly painful, slightly painful on an empty stomach, after the meal mild pain etc.
Effectively: the slight pantothenic acid of stomach, stomach are slightly painful, painful on an empty stomach, after the meal mild pain etc.
Difference (invalid): pantothenic acid, have a stomach-ache, on an empty stomach painful, pain etc. after the meal
Various symptoms do not have the changer.
5, result and analysis (seeing Table 1)
Table 1 liang group curative effect relatively
| Group | The example number | Cure | Produce effects | Effectively | Difference | Effective percentage (%) |
| The treatment group | 230 | 100 | 86 | 42 | 2 | 99.1 |
| Matched group | 70 | 10 | 18 | 23 | 19 | 72.9 |
The curative effect of treatment group as can be seen from Table 1 obviously is better than matched group, and its total effective rate, cure rate (99.1%, 43.5%) are all apparently higher than matched group (72.9%, 14.3%).
Claims (3)
1, a kind of Chinese medicine preparation for the treatment of gastric ulcer is characterized in that being made by following bulk drugs: Sanguis Draxonis 15-35 part, Radix Glycyrrhizae 5--25 part, Os Sepiae 15-35 part, Radix Notoginseng 10--30 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-25 part.
2, the Chinese medicine preparation of treatment gastric ulcer according to claim 1 is characterized in that being made by following bulk drugs: Sanguis Draxonis 20-30 part, Radix Glycyrrhizae 10--20 part, Os Sepiae 20--30 part, Radix Notoginseng 15--25 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 10--20 part.
3, the Chinese medicine preparation of treatment gastric ulcer according to claim 2 is characterized in that being made by following bulk drugs: 25 parts of Sanguis Draxonis, 15 parts in Radix Glycyrrhizae, 25 parts of Os Sepiae, 20 parts of Radix Notoginseng, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100179101A CN1302800C (en) | 2005-08-18 | 2005-08-18 | Chinese traditional medicine preparation for curing gastric ulcer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100179101A CN1302800C (en) | 2005-08-18 | 2005-08-18 | Chinese traditional medicine preparation for curing gastric ulcer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1733166A true CN1733166A (en) | 2006-02-15 |
| CN1302800C CN1302800C (en) | 2007-03-07 |
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ID=36075921
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005100179101A Expired - Fee Related CN1302800C (en) | 2005-08-18 | 2005-08-18 | Chinese traditional medicine preparation for curing gastric ulcer |
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| CN (1) | CN1302800C (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102872342A (en) * | 2012-10-15 | 2013-01-16 | 董志勇 | Chinese medicinal composition for treating gastric ulcer |
| CN105998689A (en) * | 2016-06-22 | 2016-10-12 | 郑亮 | Slow release medicament of non-steroid anti-inflammatory drugs and preparation method of slow release medicament |
| CN106039019A (en) * | 2016-07-15 | 2016-10-26 | 李冲达 | Traditional Chinese medicinal preparation for treating gastrohelcosis and method for preparing traditional Chinese medicinal preparation for treating gastrohelcosis |
| CN106215090A (en) * | 2016-08-29 | 2016-12-14 | 江苏苏南药业实业有限公司 | A kind of compound traditional Chinese medicine composite treating gastric ulcer and preparation method thereof |
| CN107737245A (en) * | 2017-11-01 | 2018-02-27 | 李文英 | A kind of Chinese medicine for treating stomach trouble |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1067272C (en) * | 1998-12-02 | 2001-06-20 | 曾庆湘 | Powder for curing gastric ulcer |
| CN1223372C (en) * | 2003-11-10 | 2005-10-19 | 孙建民 | Oyster capsule for gastric disease and its preparation |
-
2005
- 2005-08-18 CN CNB2005100179101A patent/CN1302800C/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102872342A (en) * | 2012-10-15 | 2013-01-16 | 董志勇 | Chinese medicinal composition for treating gastric ulcer |
| CN102872342B (en) * | 2012-10-15 | 2014-07-23 | 济南伟传信息技术有限公司 | Chinese medicinal composition for treating gastric ulcer |
| CN105998689A (en) * | 2016-06-22 | 2016-10-12 | 郑亮 | Slow release medicament of non-steroid anti-inflammatory drugs and preparation method of slow release medicament |
| CN106039019A (en) * | 2016-07-15 | 2016-10-26 | 李冲达 | Traditional Chinese medicinal preparation for treating gastrohelcosis and method for preparing traditional Chinese medicinal preparation for treating gastrohelcosis |
| CN106215090A (en) * | 2016-08-29 | 2016-12-14 | 江苏苏南药业实业有限公司 | A kind of compound traditional Chinese medicine composite treating gastric ulcer and preparation method thereof |
| CN107737245A (en) * | 2017-11-01 | 2018-02-27 | 李文英 | A kind of Chinese medicine for treating stomach trouble |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1302800C (en) | 2007-03-07 |
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Granted publication date: 20070307 |