CN1696279A - Method for preparing epsilon-polylysine and salts thereof by using northern sporotrichum PL 6-3 - Google Patents
Method for preparing epsilon-polylysine and salts thereof by using northern sporotrichum PL 6-3 Download PDFInfo
- Publication number
- CN1696279A CN1696279A CN 200510037774 CN200510037774A CN1696279A CN 1696279 A CN1696279 A CN 1696279A CN 200510037774 CN200510037774 CN 200510037774 CN 200510037774 A CN200510037774 A CN 200510037774A CN 1696279 A CN1696279 A CN 1696279A
- Authority
- CN
- China
- Prior art keywords
- polylysine
- epsilon
- northern
- salts
- substratum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108010039918 Polylysine Proteins 0.000 title claims abstract description 33
- 150000003839 salts Chemical class 0.000 title claims abstract description 18
- 238000000034 method Methods 0.000 title claims abstract description 16
- 241001085826 Sporotrichum Species 0.000 title 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 9
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000003456 ion exchange resin Substances 0.000 claims abstract description 6
- 229920003303 ion-exchange polymer Polymers 0.000 claims abstract description 6
- 229910052799 carbon Inorganic materials 0.000 claims abstract description 5
- 238000000926 separation method Methods 0.000 claims abstract description 3
- 241000204057 Kitasatospora Species 0.000 claims description 15
- 230000001580 bacterial effect Effects 0.000 claims description 15
- 239000007788 liquid Substances 0.000 claims description 15
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 9
- 239000008103 glucose Substances 0.000 claims description 9
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims description 8
- FRXSZNDVFUDTIR-UHFFFAOYSA-N 6-methoxy-1,2,3,4-tetrahydroquinoline Chemical compound N1CCCC2=CC(OC)=CC=C21 FRXSZNDVFUDTIR-UHFFFAOYSA-N 0.000 claims description 5
- 229940041514 candida albicans extract Drugs 0.000 claims description 5
- 239000012138 yeast extract Substances 0.000 claims description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 4
- 229920002472 Starch Polymers 0.000 claims description 4
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 4
- -1 semi-lactosi Chemical compound 0.000 claims description 4
- 238000004321 preservation Methods 0.000 claims description 3
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 claims description 2
- 235000019890 Amylum Nutrition 0.000 claims description 2
- 229920000742 Cotton Polymers 0.000 claims description 2
- 244000068988 Glycine max Species 0.000 claims description 2
- 235000010469 Glycine max Nutrition 0.000 claims description 2
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 claims description 2
- 239000001888 Peptone Substances 0.000 claims description 2
- 108010080698 Peptones Proteins 0.000 claims description 2
- MUPFEKGTMRGPLJ-RMMQSMQOSA-N Raffinose Natural products O(C[C@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O[C@@]2(CO)[C@H](O)[C@@H](O)[C@@H](CO)O2)O1)[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 MUPFEKGTMRGPLJ-RMMQSMQOSA-N 0.000 claims description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 2
- 229930006000 Sucrose Natural products 0.000 claims description 2
- MUPFEKGTMRGPLJ-UHFFFAOYSA-N UNPD196149 Natural products OC1C(O)C(CO)OC1(CO)OC1C(O)C(O)C(O)C(COC2C(C(O)C(O)C(CO)O2)O)O1 MUPFEKGTMRGPLJ-UHFFFAOYSA-N 0.000 claims description 2
- 240000008042 Zea mays Species 0.000 claims description 2
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims description 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 2
- SRBFZHDQGSBBOR-LECHCGJUSA-N alpha-D-xylose Chemical compound O[C@@H]1CO[C@H](O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-LECHCGJUSA-N 0.000 claims description 2
- SRBFZHDQGSBBOR-QMKXCQHVSA-N alpha-L-arabinopyranose Chemical compound O[C@H]1CO[C@@H](O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-QMKXCQHVSA-N 0.000 claims description 2
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 claims description 2
- 239000004202 carbamide Substances 0.000 claims description 2
- 235000005822 corn Nutrition 0.000 claims description 2
- 235000011187 glycerol Nutrition 0.000 claims description 2
- 239000000413 hydrolysate Substances 0.000 claims description 2
- 235000013379 molasses Nutrition 0.000 claims description 2
- 125000001477 organic nitrogen group Chemical group 0.000 claims description 2
- 235000019319 peptone Nutrition 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims description 2
- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 claims description 2
- 239000005720 sucrose Substances 0.000 claims description 2
- 229960003487 xylose Drugs 0.000 claims description 2
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 abstract description 6
- 241000894006 Bacteria Species 0.000 abstract description 5
- 238000000855 fermentation Methods 0.000 abstract description 5
- 230000004151 fermentation Effects 0.000 abstract description 5
- 241000233866 Fungi Species 0.000 abstract description 3
- 239000001963 growth medium Substances 0.000 abstract description 3
- 238000012258 culturing Methods 0.000 abstract description 2
- 238000012216 screening Methods 0.000 abstract description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 241001052560 Thallis Species 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 9
- 239000002609 medium Substances 0.000 description 6
- 108020004465 16S ribosomal RNA Proteins 0.000 description 5
- 229920001817 Agar Polymers 0.000 description 5
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 5
- 239000008272 agar Substances 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 244000005700 microbiome Species 0.000 description 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
- 241000060682 Kitasatospora sp. Species 0.000 description 4
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 4
- 229930195722 L-methionine Natural products 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 230000007062 hydrolysis Effects 0.000 description 3
- 238000006460 hydrolysis reaction Methods 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- 241000187759 Streptomyces albus Species 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
- 239000012776 electronic material Substances 0.000 description 2
- 238000001962 electrophoresis Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 229920001519 homopolymer Polymers 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 239000008267 milk Substances 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 description 2
- 239000000049 pigment Substances 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 238000011218 seed culture Methods 0.000 description 2
- 238000012807 shake-flask culturing Methods 0.000 description 2
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000006228 supernatant Substances 0.000 description 2
- BBBFYZOJHSYQMW-LGDQNDJISA-N (2s)-2,4-diamino-4-oxobutanoic acid;(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanal Chemical compound OC(=O)[C@@H](N)CC(N)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O BBBFYZOJHSYQMW-LGDQNDJISA-N 0.000 description 1
- UQZSVIGPZAULMV-DKWTVANSSA-N (2s)-2,4-diamino-4-oxobutanoic acid;propane-1,2,3-triol Chemical compound OCC(O)CO.OC(=O)[C@@H](N)CC(N)=O UQZSVIGPZAULMV-DKWTVANSSA-N 0.000 description 1
- 241000186361 Actinobacteria <class> Species 0.000 description 1
- 102000012286 Chitinases Human genes 0.000 description 1
- 108010022172 Chitinases Proteins 0.000 description 1
- 241000192125 Firmicutes Species 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 239000001828 Gelatine Substances 0.000 description 1
- 241000593854 Kitasatospora kifunensis Species 0.000 description 1
- 241001405552 Kitasatospora recifensis Species 0.000 description 1
- XUYPXLNMDZIRQH-LURJTMIESA-N N-acetyl-L-methionine Chemical compound CSCC[C@@H](C(O)=O)NC(C)=O XUYPXLNMDZIRQH-LURJTMIESA-N 0.000 description 1
- 241000237502 Ostreidae Species 0.000 description 1
- 238000012300 Sequence Analysis Methods 0.000 description 1
- 241000187310 Streptomyces noursei Species 0.000 description 1
- 241000204060 Streptomycetaceae Species 0.000 description 1
- 241001655322 Streptomycetales Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000003905 agrochemical Substances 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 235000011114 ammonium hydroxide Nutrition 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 239000012876 carrier material Substances 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 239000012225 czapek media Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003797 essential amino acid Substances 0.000 description 1
- 235000020776 essential amino acid Nutrition 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 238000005189 flocculation Methods 0.000 description 1
- 230000016615 flocculation Effects 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 229910017053 inorganic salt Inorganic materials 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- HVGQWHMSVYODLJ-GFCCVEGCSA-N melanochrome Natural products CC1(C)Oc2cc3OC(=CC(=O)c3c(O)c2C[C@H]1O)CO HVGQWHMSVYODLJ-GFCCVEGCSA-N 0.000 description 1
- GMKMEZVLHJARHF-SYDPRGILSA-N meso-2,6-diaminopimelic acid Chemical compound [O-]C(=O)[C@@H]([NH3+])CCC[C@@H]([NH3+])C([O-])=O GMKMEZVLHJARHF-SYDPRGILSA-N 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 230000000877 morphologic effect Effects 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 235000003170 nutritional factors Nutrition 0.000 description 1
- 239000006877 oatmeal agar Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 235000020636 oyster Nutrition 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 238000004886 process control Methods 0.000 description 1
- 238000001243 protein synthesis Methods 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 238000012882 sequential analysis Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M sodium chloride Inorganic materials [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 238000004809 thin layer chromatography Methods 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 229920001351 ε-poly-L-lysine Polymers 0.000 description 1
Images
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Description
Substratum | Aerial hyphae | Substrate mycelium | Soluble pigment |
Gao Shi synthesizes a glucose-asparagine agar glycerine-asparagine agar czapek agar medium inorganic salts starch agar gelatin agar oatmeal agar | Canescence, the relatively poor canescence of growing, well-grown, fine and close canescence, well-grown, compact powdered, white, growth moderate canescence, growth moderate oyster white does not almost have white abundant | The light grey milky white of white milky white~faint yellow white, faint yellow yellowish-brown | Do not have |
Claims (5)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2005100377742A CN1320099C (en) | 2005-02-04 | 2005-02-04 | Method for preparing epsilon-polylysine and salts thereof by using northern sporotrichum PL 6-3 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2005100377742A CN1320099C (en) | 2005-02-04 | 2005-02-04 | Method for preparing epsilon-polylysine and salts thereof by using northern sporotrichum PL 6-3 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1696279A true CN1696279A (en) | 2005-11-16 |
CN1320099C CN1320099C (en) | 2007-06-06 |
Family
ID=35349172
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB2005100377742A Expired - Fee Related CN1320099C (en) | 2005-02-04 | 2005-02-04 | Method for preparing epsilon-polylysine and salts thereof by using northern sporotrichum PL 6-3 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN1320099C (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101580865B (en) * | 2008-05-15 | 2012-09-26 | 上海医药工业研究院 | Method for sieving Epsilon-polylysine high-producing strains |
CN104193988A (en) * | 2014-09-01 | 2014-12-10 | 江南大学 | Method for flocculating and sterilizing fermentation solution of epsilon-polylysine |
CN105053517A (en) * | 2015-09-21 | 2015-11-18 | 山东西王糖业有限公司 | Production method of antibiotic-free feed |
CN105112301A (en) * | 2015-09-06 | 2015-12-02 | 樟树市狮王生物科技有限公司 | Natural preservative epsilon-polylysine strain and methods for screening, fermenting and identifying same |
CN107164417A (en) * | 2017-05-17 | 2017-09-15 | 郑州拜纳佛生物工程股份有限公司 | A kind of production method of ε polylysines |
CN116855416A (en) * | 2023-07-13 | 2023-10-10 | 贵州省茶叶研究所 | Bacterial strain for antagonizing plant disease pathogenic bacteria, microbial inoculum and application |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2746372B2 (en) * | 1988-03-11 | 1998-05-06 | 科研製薬株式会社 | F-0368 substance |
WO2003010307A1 (en) * | 2001-07-26 | 2003-02-06 | Ajinomoto Co., Inc. | Peptide synthase gene, peptide synthase and process for producing dipeptide |
-
2005
- 2005-02-04 CN CNB2005100377742A patent/CN1320099C/en not_active Expired - Fee Related
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101580865B (en) * | 2008-05-15 | 2012-09-26 | 上海医药工业研究院 | Method for sieving Epsilon-polylysine high-producing strains |
CN104193988A (en) * | 2014-09-01 | 2014-12-10 | 江南大学 | Method for flocculating and sterilizing fermentation solution of epsilon-polylysine |
CN105112301A (en) * | 2015-09-06 | 2015-12-02 | 樟树市狮王生物科技有限公司 | Natural preservative epsilon-polylysine strain and methods for screening, fermenting and identifying same |
CN105053517A (en) * | 2015-09-21 | 2015-11-18 | 山东西王糖业有限公司 | Production method of antibiotic-free feed |
CN105053517B (en) * | 2015-09-21 | 2018-09-28 | 山东西王糖业有限公司 | A kind of production method of nonreactive feed |
CN107164417A (en) * | 2017-05-17 | 2017-09-15 | 郑州拜纳佛生物工程股份有限公司 | A kind of production method of ε polylysines |
CN116855416A (en) * | 2023-07-13 | 2023-10-10 | 贵州省茶叶研究所 | Bacterial strain for antagonizing plant disease pathogenic bacteria, microbial inoculum and application |
CN116855416B (en) * | 2023-07-13 | 2023-12-12 | 贵州省茶叶研究所 | Bacterial strain for antagonizing plant disease pathogenic bacteria, microbial inoculum and application |
Also Published As
Publication number | Publication date |
---|---|
CN1320099C (en) | 2007-06-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN1273004C (en) | Method for producing hedgehog fungus and special culture medium thereof | |
CN1171521C (en) | Method of culturing mycellium by using grain, its product use for culturing product | |
CN1313498C (en) | Process for producing pullulan | |
CN1320099C (en) | Method for preparing epsilon-polylysine and salts thereof by using northern sporotrichum PL 6-3 | |
CN1769424A (en) | Bacillus strain and its uses | |
CN1966670A (en) | Bacillus laterosporus and soil inoculation agent prepared from the strain | |
CN112553284B (en) | Method for producing citric acid by degrading coarse feed through natural symbiotic mixed culture | |
CN101037658A (en) | Bacillus subtilis ZJB-063 and its application | |
CN101045910A (en) | Preparation of propionic acid and co-production of vitamin B by using propionibacterium freudenre NX-412Method (2) | |
CN1269951C (en) | Bacillus and its use of preparation of gama-polycysteine | |
CN1185336C (en) | Li's Trichoderma strains and use thereof | |
CN101078005A (en) | Bacillus pumilus and application of the same in producing natural vanillin by biologically converting iso-eugenol | |
CN110938666B (en) | Preparation method of microbial chitosan | |
CN1398979A (en) | Fermentation process of ash tree flower and production process of its polyglycopeptide | |
CN102086441B (en) | Streptomyces griseofuscus strain and method for preparing epsilon-polylysine and salt thereof by utilizing same | |
CN1827771A (en) | Microorganism polysaccharide and its preparation method and application | |
CN110305819A (en) | One plant of feather efficient degrading bacterial strain and its application | |
CN1173029C (en) | Fermentation process of producing agaric and its culture medium | |
CN1279159C (en) | CZ-81 strain of 'Baibachi' bacterium and artificial culture method | |
CN100340669C (en) | 10 ton liquid submerged femrentation culturing method of Gleoesterum incarnatum | |
CN87100655A (en) | Method for producing L-sorbose | |
CN1737111A (en) | Antrodia mycelium active substance preparation method and its components | |
CN1904032A (en) | Xanthan gum degradation bacteria, its fermentation method and application | |
CN108018246A (en) | Bacterial strain and its application of one plant of coproduction chitosan enzyme and gamma-polyglutamic acid | |
CN1513983A (en) | Bactericide bandung mycin and its upplication |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20051116 Assignee: ZHANGSHU CITY LION BIOTECHNOLOGY CO.,LTD. Assignor: Nanjing Tech University Contract record no.: 2013320000330 Denomination of invention: Method for preparing epsilon lysine and its salt by using PL6-3 of northern spore fungus Granted publication date: 20070606 License type: Exclusive License Record date: 20130415 |
|
LICC | Enforcement, change and cancellation of record of contracts on the licence for exploitation of a patent or utility model | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20070606 Termination date: 20210204 |
|
CF01 | Termination of patent right due to non-payment of annual fee |