CN1681845A - 血管紧张素-ⅱⅰ型受体单克隆抗体的治疗性用途 - Google Patents
血管紧张素-ⅱⅰ型受体单克隆抗体的治疗性用途 Download PDFInfo
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
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- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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Abstract
Description
Claims (13)
Applications Claiming Priority (3)
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GB0219524.6 | 2002-08-21 | ||
GBGB0219524.6A GB0219524D0 (en) | 2002-08-21 | 2002-08-21 | Therapeutic uses of monoclonal antibodies to the angiotensin-II type-1 receptor |
PCT/GB2003/003758 WO2004018519A2 (en) | 2002-08-21 | 2003-08-21 | Therapeutic uses of monoclonal antibodies to the angiotensin-ii type-1 receptor |
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CN201010167267A Division CN101837124A (zh) | 2002-08-21 | 2003-08-21 | 血管紧张素-iii型受体单克隆抗体的治疗性用途 |
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CN1681845A true CN1681845A (zh) | 2005-10-12 |
CN1681845B CN1681845B (zh) | 2011-08-17 |
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CN201010167267A Pending CN101837124A (zh) | 2002-08-21 | 2003-08-21 | 血管紧张素-iii型受体单克隆抗体的治疗性用途 |
CN038222051A Expired - Fee Related CN1681845B (zh) | 2002-08-21 | 2003-08-21 | 血管紧张素-ⅱⅰ型受体单克隆抗体的治疗性用途 |
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CN201010167267A Pending CN101837124A (zh) | 2002-08-21 | 2003-08-21 | 血管紧张素-iii型受体单克隆抗体的治疗性用途 |
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US (3) | US7951904B2 (zh) |
EP (2) | EP1534750B1 (zh) |
JP (2) | JP4652807B2 (zh) |
CN (2) | CN101837124A (zh) |
AT (1) | ATE554102T1 (zh) |
AU (1) | AU2003263294A1 (zh) |
CA (1) | CA2496422C (zh) |
DK (1) | DK1534750T3 (zh) |
ES (2) | ES2385976T3 (zh) |
GB (1) | GB0219524D0 (zh) |
WO (1) | WO2004018519A2 (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019047921A1 (zh) * | 2017-09-08 | 2019-03-14 | 武汉华纪元生物技术开发有限公司 | 短肽atr001以及由短肽制备具有偏向性调节at1r功能的单克隆抗体和应用 |
CN115838425A (zh) * | 2022-08-31 | 2023-03-24 | 首都医科大学 | 一种靶向血管紧张素ii 1型受体细胞外第二环的抗体及其应用 |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0219524D0 (en) | 2002-08-21 | 2002-10-02 | Queen Mary & Westfield College | Therapeutic uses of monoclonal antibodies to the angiotensin-II type-1 receptor |
FR2873699B1 (fr) * | 2004-07-29 | 2009-08-21 | Pierre Fabre Medicament Sa | Nouveaux anticorps anti igf ir rt leurs utilisations |
CA2668725A1 (en) * | 2006-11-09 | 2008-05-22 | Ore Pharmaceuticals Inc. | Breast cancer screening and treatment methods |
GB0802931D0 (en) * | 2008-02-18 | 2008-03-26 | Queen Mary & Westfield College | Synthetic scFv analogue to the 6313/G2 (anti angiotensin II type 1 receptor) monoclonal anitbody variable regions |
WO2011027257A2 (en) | 2009-09-03 | 2011-03-10 | Pfizer Vaccines Llc | Pcsk9 vaccine |
JP2011111422A (ja) * | 2009-11-27 | 2011-06-09 | Sekisui Chem Co Ltd | モノクローナル抗体 |
CN103613660A (zh) * | 2013-11-25 | 2014-03-05 | 博奥赛斯(天津)生物科技有限公司 | 一种血管紧张素完全抗原的制备方法 |
EP3773483A4 (en) * | 2018-04-06 | 2022-01-26 | Amma Therapeutics, Inc. | CONTROLLED RELEASE THERAPEUTIC COMPOSITION |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
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US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
DE69127627T2 (de) | 1990-08-29 | 1998-02-19 | Genpharm Int | Produktion und Nützung nicht-menschliche transgentiere zur Produktion heterologe Antikörper |
US5427922A (en) * | 1992-04-07 | 1995-06-27 | Takeda Chemical Industries, Ltd. | DNA encoding a new angiotensin II type 1 receptor subtype and its expression |
GB9223377D0 (en) | 1992-11-04 | 1992-12-23 | Medarex Inc | Humanized antibodies to fc receptors for immunoglobulin on human mononuclear phagocytes |
CA2126967A1 (en) | 1992-11-04 | 1994-05-11 | Anna M. Wu | Novel antibody construct |
GB9319877D0 (en) | 1993-09-27 | 1993-11-10 | Queen Mary | Novel hybridoma & monoclonal antibodies produced thereby |
TW448185B (en) | 1993-11-05 | 2001-08-01 | Lilly Co Eli | Vaccine design and production |
US6280994B1 (en) * | 1998-11-25 | 2001-08-28 | Zymogenetics, Inc. | Zace 1: a human metalloenzyme |
WO2002061087A2 (en) * | 2000-12-19 | 2002-08-08 | Lifespan Biosciences, Inc. | Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides |
GB0219524D0 (en) | 2002-08-21 | 2002-10-02 | Queen Mary & Westfield College | Therapeutic uses of monoclonal antibodies to the angiotensin-II type-1 receptor |
US20060003483A1 (en) | 2003-07-07 | 2006-01-05 | Wolff Larry L | Optoelectronic packaging with embedded window |
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2002
- 2002-08-21 GB GBGB0219524.6A patent/GB0219524D0/en not_active Ceased
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2003
- 2003-08-21 EP EP03792528A patent/EP1534750B1/en not_active Expired - Lifetime
- 2003-08-21 US US10/525,277 patent/US7951904B2/en not_active Expired - Fee Related
- 2003-08-21 ES ES03792528T patent/ES2385976T3/es not_active Expired - Lifetime
- 2003-08-21 EP EP10005016.0A patent/EP2228390B1/en not_active Expired - Lifetime
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- 2003-08-21 AT AT03792528T patent/ATE554102T1/de active
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2010
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2013
- 2013-01-24 US US13/749,180 patent/US20130202604A1/en not_active Abandoned
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019047921A1 (zh) * | 2017-09-08 | 2019-03-14 | 武汉华纪元生物技术开发有限公司 | 短肽atr001以及由短肽制备具有偏向性调节at1r功能的单克隆抗体和应用 |
CN115838425A (zh) * | 2022-08-31 | 2023-03-24 | 首都医科大学 | 一种靶向血管紧张素ii 1型受体细胞外第二环的抗体及其应用 |
Also Published As
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JP5208975B2 (ja) | 2013-06-12 |
EP2228390B1 (en) | 2018-12-19 |
JP2010106035A (ja) | 2010-05-13 |
WO2004018519A3 (en) | 2004-06-03 |
EP1534750B1 (en) | 2012-04-18 |
DK1534750T3 (da) | 2012-07-23 |
ES2713057T3 (es) | 2019-05-17 |
CA2496422C (en) | 2013-06-25 |
EP1534750A2 (en) | 2005-06-01 |
CN101837124A (zh) | 2010-09-22 |
ATE554102T1 (de) | 2012-05-15 |
US20060034839A1 (en) | 2006-02-16 |
GB0219524D0 (en) | 2002-10-02 |
ES2385976T3 (es) | 2012-08-06 |
JP2006513982A (ja) | 2006-04-27 |
US20130202604A1 (en) | 2013-08-08 |
JP4652807B2 (ja) | 2011-03-16 |
US8383108B2 (en) | 2013-02-26 |
WO2004018519A2 (en) | 2004-03-04 |
US7951904B2 (en) | 2011-05-31 |
CA2496422A1 (en) | 2004-03-04 |
CN1681845B (zh) | 2011-08-17 |
EP2228390A1 (en) | 2010-09-15 |
US20110256139A1 (en) | 2011-10-20 |
AU2003263294A1 (en) | 2004-03-11 |
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