CN1644169A - Ultrasonic diagnostic equipment - Google Patents

Ultrasonic diagnostic equipment Download PDF

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Publication number
CN1644169A
CN1644169A CNA2004100997204A CN200410099720A CN1644169A CN 1644169 A CN1644169 A CN 1644169A CN A2004100997204 A CNA2004100997204 A CN A2004100997204A CN 200410099720 A CN200410099720 A CN 200410099720A CN 1644169 A CN1644169 A CN 1644169A
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image data
injection
dynamic image
past
view data
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CN100384379C (en
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中屋重光
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Canon Medical Systems Corp
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Toshiba Corp
Toshiba Medical Systems Corp
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48Diagnostic techniques
    • A61B8/481Diagnostic techniques involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/06Measuring blood flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48Diagnostic techniques
    • A61B8/488Diagnostic techniques involving Doppler signals

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  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
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  • Ultra Sonic Daignosis Equipment (AREA)
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Abstract

An ultrasound diagnosis apparatus includes a transceiver, a processor, a memory, and a display unit. The transceiver is configured to transmit an ultrasound signal to a part of a specimen and receive an echo signal resulting from the ultrasound signal transmission. The part is administered with a contrast agent. The processor is configured to prepare a moving image data based on the received echo signal. The memory is configured to store the prepared moving image data as a past moving image data. The display unit is configured to display the past moving image data and a current moving image data prepared by the processor in parallel. The past moving image data is displayed in response to an administration initiation of the contrast agent for the current moving image data.

Description

Supersonic diagnostic appts
Relevant application is introduced
The application is that the P2003-429740 of Japanese patent application No. formerly according to December in 2003 application on the 25th proposes, and requires it as priority, and the full content of this application is incorporated herein with for referencial use.
Technical field
The present invention relates to a kind of supersonic diagnostic appts that shows enhanced ultrasonography.The invention still further relates to a kind of method that shows enhanced ultrasonography.
Background technology
As everyone knows, supersonic diagnostic appts has many advantages because of it shows easily, for example, only is used for patient's body surface by ultrasound probe and can shows heart beating or fetal movements in real time.And needn't worry in the ultra sonic imaging process, to be exposed under the x ray, therefore, for the patient be safety repeatably and do not have the danger be exposed under the x ray.In addition, for radiodiagnosis instrument, X ray computer tomoscan (CT) instrument, NMR imaging equipment etc., it is compact more that supersonic diagnostic appts can prepare dimensionally.Thereby carry out the ultrasonic imaging inspection at bedside easily.Though the size of supersonic diagnostic appts may depend on the corresponding performance of equipment, nowadays being decreased to is enough to the size that allows the user one hand carry.
As the common main therapeutic treatment of hepatocarcinoma, can often adopt percutaneous ethanol injection treatment (PEIT), percutaneous microwave condense treatment (PMCT) and radio frequency erosion (RFA).For example, in percutaneous ethanol injection treatment, puncture needle is thrust the tumor of ultrasound wave under looking like to lead.Again medicine is injected tumor to kill cancerous cell by puncture needle.In the percutaneous microwave condenses treatment, adopt the microwave irradiation tumor that it is condensed to kill cancerous cell.In radio frequency corroded, high temperature heating tumor was to kill cancerous cell.Usually be easy to carry out above-mentioned any therapeutic treatment.And the patient may need not stand a lot of miseries that these treatments bring.
Whether successfully adopt usually Dynamic CT equipment, NMR (Nuclear Magnetic Resonance)-imaging equipment etc. that these therapeutic treatments carry out are confirmed imaging patients.It is preceding to tumor-localizing that these medical imaging devices also can be used for treatment.Yet, improve because supersonic diagnostic appts is existing recently, and introduced the contrast agent that is used for ultrasonic imaging, nowadays supersonic diagnostic appts also is used to find out or definite knub position.In the enhanced ultrasound imaging techniques of this kind, for example, in heart or abdominal organ checking process, can strengthen blood flow indication by the intravascular injection contrast agent and assess blood flow dynamic, as described in Japanese Unexamined Patent Publication No 2003-153900.
When adopting enhanced ultrasound imaging techniques to determine the therapeutic treatment success or not, the image with the same position that obtains behind specific part (the being generally tumor locus) image that obtains before the therapeutic treatment and the therapeutic treatment compares usually.For example, when blood before the therapeutic treatment flows into tumor locus by blood vessel, if blood no longer flows into tumor locus by blood vessel and just proves that therapeutic treatment succeeds behind the therapeutic treatment.Just prove that this kind therapeutic treatment has been failed and to carry out once more if blood still flows into tumor locus by blood vessel behind the therapeutic treatment.
In the enhanced ultrasound imaging techniques of this kind, know behind the injection of contrast medium that be very important the time phase of ultrasonography data in the whole process.For liver, for example, this kind contrast agent flows into Hepatic artery, portal vein etc.As a result, the ultrasonography medium vessels of display device demonstration has strengthened.The enhanced image of this blood vessel can be called blood-vessel image.As time goes on, contrast agent continues to flow into the blood capillary and the tissue of liver inside.Therefore, liver overall enhanced in the ultrasonography that display device shows.The enhanced image of this blood vessel, blood capillary and tissue (or organ such as liver) can be called perfusion image.
As mentioned above, according to the time phase in the whole process behind the injection of contrast medium, the image that show becomes perfusion image from blood-vessel image.Therefore, time phase, information and corresponding image were very important as diagnostic message.For this reason, the supersonic diagnostic appts that can strengthen ultrasound imaging techniques generally includes the injection timer of measuring the time after the injection of contrast medium.That is to say,, need to obtain the ultrasonography (or dynamic image) of therapeutic treatment front and back usually in order to determine the therapeutic treatment success or not.
Strengthen in the ultrasound imaging techniques in utilization, may need to open the injection timer during contrast-medium injection, also begin to store simultaneously ultrasonography.In addition, behind the therapeutic treatment, may also need from the ultrasound wave picture library of storage, to take out the suitable enhancing image that obtains before the therapeutic treatment.At last, whether successful in order to determine this kind therapeutic treatment, may need according to the time phase after the contrast-medium injection ultrasonography that obtains before and after the therapeutic treatment being shown and contrasting.Therefore, the user of supersonic diagnostic appts may need to experience from being imaged onto definite loaded down with trivial details operation.
Summary of the invention
First aspect of the present invention provides a kind of supersonic diagnostic appts that comprises transceiver, processor, memorizer and display device.Transceiver is used for ultrasonic signal is sent to certain position of sample and the echo signal that the received ultrasonic signal transmission obtains.This position is by injection of contrast medium.Processor is used for forming dynamic image data according to the echo signal that obtains.Memorizer is used to store the dynamic image data of above-mentioned formation as the past dynamic image data.Display device is used for the past and the present dynamic view data of video-stream processor formation simultaneously.The contrast-medium injection of current dynamic image data begins just to show dynamic image data in the past.
Second aspect of the present invention provides a kind of supersonic diagnostic appts that comprises transceiver, processor, memorizer and display device.Transceiver is used for ultrasonic signal is sent to a part of sample and the echo signal that the received ultrasonic signal transmission obtains.This position is by injection of contrast medium.Processor is used for forming dynamic image data according to the echo signal that obtains.Memorizer is used to store the view data of piece image at least as the past dynamic image data.Display device is used for the past and the present dynamic view data of video-stream processor formation simultaneously.The contrast-medium injection of current dynamic image data begins just to show dynamic image data in the past.
The 3rd aspect of the present invention provides a kind of method that shows the ultrasonography that supersonic diagnostic appts obtains.It is that first ultrasonic signal is sent to a part of sample and receives first echo signal that first ultrasound signal transmission obtains that this method begins.This position is by injection of contrast medium.This method continues to form first dynamic image data and with its dynamic image data of being stored as over according to first echo signal of receiving.This method further continues second ultrasound signal transmission to this position of sample and receive second echo signal that second ultrasound signal transmission obtains.Second contrast agent is injected at this position, forms second dynamic image data according to second echo signal of receiving, the past motion graphics data of video-stream processor formation simultaneously and second dynamic image data are as ultrasonography.The contrast-medium injection of current dynamic image data begins just to show dynamic image data in the past.
Description of drawings
To be easy to embodiment of the present invention and plurality of advantages thereof are carried out more complete evaluation according to detailed description below in conjunction with respective drawings, wherein:
Fig. 1 is the sketch map of expression supersonic diagnostic appts example arrangement structure;
Fig. 2 is that the expression therapeutic treatment is to the flow chart of demonstration user with the enhancing ultrasonic imaging;
Fig. 3 is the sketch map that the touch screen example of supersonic diagnostic appts operational mode is specified in expression;
Fig. 4 is the sketch map of presentation video data show example;
Fig. 5 is the demonstration user flow chart that strengthens ultrasonic imaging behind the expression therapeutic treatment;
Fig. 6 is the sketch map of the image name example of view data before a series of treatments of expression;
Fig. 7 is the sketch map that the expression blood-vessel image shows comparison example;
Fig. 8 is the sketch map that the expression perfusion image shows comparison example; With
Fig. 9 is the improved structure chart of expression diagnostic ultrasound equipment shown in Figure 1.
The specific embodiment
Embodiment of the present invention will be described with reference to respective drawings.
Can be used for determining according to the demonstration that strengthens ultrasound imaging techniques whether the therapeutic treatment of any region of interest in sample such as the patient's body is successful.But describing below one is the example that the liver soft tissue is judged by showing that enhanced blood flows into interested position.
Fig. 1 is an expression supersonic diagnostic appts example arrangement structure chart.Supersonic diagnostic appts 1 can comprise main equipment 11, ultrasound probe 12, input equipment 13 and display device 14.
Ultrasound probe 12 sends to the position of patient P with ultrasonic signal (or pulse) and receives the echo signal that is produced by ultrasonic transmission.Ultrasound probe 12 comprises that the piezoelectric transducer that is arranged in array in a large number is as the reversible converting member of acoustic-electric.Described piezoelectric transducer receives potential pulse and corresponding the vibration to produce ultrasonic pulse as ultrasonic signal that main equipment 11 provides.When ultrasound probe 12 contacted with the body surface of patient P, ultrasonic signal entered in the body of patient P and on the different surface of specific acoustic impedance and reflects.Reflected signal returns ultrasound probe 12 as echo signal.Piezoelectric transducer converts thereof into the signal of telecommunication after receiving echo signal.The amplitude of echo signal may depend on surperficial acoustic impedance rate variance.In addition, when ultrasonic signal reflex time on dynamic main body bloody path such as blood flow or heart wall, echo signal may produce a frequency displacement, and this frequency displacement depends on corresponding to the dynamic main body speed durection component according to ultrasonic signal (or ultrasonic beam) direction of Doppler effect.
Input equipment 13 can comprise button, switch, keyboard, mouse, rail ball, stick and/or touch order screen.Input equipment 13 can comprise the injection timer switch of any above-mentioned form.Input equipment 13 can be used for importing various instructions.Therefore, the user of supersonic diagnostic appts 1, for example, the doctor can import the image-forming condition information of ultrasonic imaging as instruction, for example, result's dynamic range, transmission frequency, transmission focus, pulse recurrence frequency (PRF), pentrution and/or scanning density flow rates.Input equipment 13 also can be used for input picture name information, patient information, as, patient's name and patient's identification card number (ID) and/or etc.
Display device 14 can comprise that cathode ray tube (CRT) shows or liquid crystal display (LCD), shows ultrasonography data (or ultrasonography) usually.Still image or dynamic image that described ultrasonography can be that main equipment 11 provides about this position of patient P.Hereinafter, except as otherwise noted, " view data " is meant dynamic image.
Main equipment 11 can comprise the transmission with receiving equipment 21, echo signal processor 22, control appliance 23, memorizer 24, become figure equipment 25 and interface 26.
This transmission and receiving equipment 21 provide the ultrasound probe 12 with the predetermined high frequency voltage pulse of about f0Hz.This transmission and receiving equipment 21 also receive and amplify echo signal from ultrasound probe 12, and the echo signal of further receiving by default routine processes.
Echo signal processor 22 can comprise B-schema processor 31 and doppler mode processor 32.In echo signal processor 22, when echo signal belonged to the B-pattern, transmission and receiving equipment 21 offered B-schema processor 31 with echo signal and handle.When echo signal belonged to Doppler-pattern, transmission and receiving equipment 21 offered 32 processing of Doppler-schema processor with echo signal.B-schema processor 31 is handled echo signal to produce B-mode image data.Doppler-schema processor 32 is handled echo signal to produce Doppler-mode image data.
Control appliance 23 control supersonic diagnostic appts 1 also can comprise the injection timer.Especially, control appliance 23 receives the instruction that input equipments 13 send and the pictorial display of control display device 14.
But memorizer 24 storage control programs and view data, described program be obtain, handle and/or display image data necessary.View data can store together with their image name (or filename), patient information such as patient's name or patient ID and imaging instantaneous time information.When ultrasonoscopy operation was finished, the various image-forming conditions when view data also can be together with ultrasonic imaging stored.This image-forming condition comprises gain dynamic range, transmission frequency, transmission focal position, pulse recurrence frequency (PRF), pentrution and/or scanning density flow rates.
The signal that becomes figure equipment 25 to handle according to echo signal processor 22 forms B-mode image data or doppler mode view data.
As required, interface 26 is connected to input equipment 13 on the control appliance 23 and miscellaneous equipment in the main equipment 11.Interface 26 also can be connected to the ultrasonic signal diagnostic equipment 1 on other the equipment.
Among Fig. 1, ultrasound probe 12 can be equivalent to " transceiver " with transmission and receiving equipment 21.Echo signal processor 22 with become figure equipment 25 can be equivalent to " processor ", also can be equivalent to " second processor ", control appliance 23 can be equivalent to " control appliance ".Memorizer 24 can be equivalent to " memorizer ".Interface 26 can be equivalent to " interface ".Input equipment 13 can be equivalent to " input equipment ".Display device 13 can be equivalent to " display device ".
Fig. 2 is the flow chart that before the expression therapeutic treatment demonstration user is strengthened ultrasonic imaging.
As shown in Figure 2, at first operation input apparatus 13 inputs of user for example, prepare to adopt supersonic diagnostic appts 1 to carry out the patient ID of imaging and the name (step S1) of patient P.Enhanced Imaging pattern (step S2) before input equipment 13 comprises a touch screen 40 as shown in Figure 3, and user button 401 is selected and treated.After selected, supersonic diagnostic appts 1 (or display device 14) requires user input picture title (or filename) so that use when the view data that will next obtain is stored in memorizer 24.User operation input apparatus 13 and input picture title be as " INJ-1 ", (step S3).
User is imported image-forming condition then, for example: gain dynamic range, transmission frequency, transmission focal position, pulse recurrence frequency (PRF), pentrution and/or scanning density flow rates (step S4).User can directly be imported above-mentioned details, also can select a default image-forming condition to each image-forming condition.Ultrasound probe 12 is placed the body surface of patient P, and ultrasound image data promptly is presented on the display device 14 according to above-mentioned input or the condition chosen, but operator's projected images.In the projection process, user check image data determine whether ultrasound probe 12 position contacting are appropriate, and whether the image-forming condition of the view data of demonstration suitable grade (step S5).If it is improper that user is determined image-forming condition, then user can be according to the image-forming condition of step S4 in this input change.
If it is suitable that user is determined image-forming condition, user just begins to give (or injection) contrast agent (step S6) to patient P.Almost user or its assistant open the injection timer switch in injection, for example, open, by, select, input or click injection timer switch (step S7).
Injection timer switch one is opened, and control appliance 23 is promptly controlled transmission and receiving system 21 makes ultrasound probe 12 that ultrasonic signal is imported in patient's body.Ultrasonic signal returns with echo signal through human body.Echo signal is handled by echo signal processor 22 by transmission and receiving equipment 21 after ultrasound probe 12 receives and converts the signal of telecommunication to.According to the signal after handling, become figure equipment 25 prepare image data.View data is presented on the display device 14.View data can be the ultrasound image data of contrast agent enhanced.Although this depends on image-forming condition, view data is real-time demonstration usually basically.Basic demonstration in real time may mean will enough be short to from ultrasound signal transmission to the time that shows allows the user sensation view data be to show in real time.Therefore, user can be observed the enhancing process of contrast agent in the view data that shows continuously.
Just begin to measure the time in the past behind the injection timer initiation.Because the unlatching of injection timer and the injection of contrast agent are almost carried out simultaneously among the step S7,, the time in the past begins the time afterwards so being pointed injection basically.In other words, can regard the startup of injection timer switch the beginning of contrast-medium injection as exactly.
Fig. 4 is the sketch map of presentation video data show example.As shown in Figure 4, the image name of step S3 input can be presented at display window 41 upper left quarters.Lapse of time (as 1 minute and 32 seconds) that the injection timer is measured can be presented at the lower right of display window 41.Display window 41 shows the image 411 of view data when time phase, (or lapse of time) was 1 minute and 32 seconds.In image 411, the dash area representative strengthens part.When flowing in the liver blood capillary through long enough time contrast agent and organizing, whole data image is strengthened and is shown as perfusion image.In Fig. 4, circle 412 is represented tumor section.Because tumor is also without therapeutic treatment, contrast agent intravascular and blood capillary flow into tumor, so the tumor locus in the circle among Fig. 4 412 also is a shade.
The view data of obtaining according to ultrasound signal transmission also is stored in the memorizer 24 with view data name " INJ-1 ".In addition, the image-forming condition imported of injection timer switch the instantaneous time information, lapse of time and the step S4 that open also stores with this view data.
After finishing above-mentioned image manipulation, user can be closed injection timer switch (step S8).In case the injection timer stops, view data stores and lapse of time information also will be ended.The Enhanced Imaging pattern is cancelled before the treatment.
If necessary same patient P is carried out similar Enhanced Imaging, but repeating step S2 to S8.
In sum, under the Enhanced Imaging pattern, injection timer one is opened before treatment, and view data and relevant information comprise that instantaneous time, lapse of time and image-forming condition just are stored in the memorizer 24 automatically.Therefore, being beneficial to user need be through common according to the required loaded down with trivial details or operation rapidly of the time of injection of contrast medium.
After the above-mentioned imaging, user just can carry out as noticeable hepatocarcinoma therapeutic treatment, for example, after the above-mentioned imaging in the same day or several days to patient P carry out percutaneous ethanol injection (PEIT), the percutaneous microwave condenses (PMCT) or radio frequency corrodes (RFA).
Behind the therapeutic treatment, user can determine in the same day or one day or several days whether this treatment is successful.
Fig. 5 is expression demonstration user strengthens ultrasonic imaging behind therapeutic treatment a flow chart.
As shown in Figure 5, at first operation input apparatus 13 input of user for example, is used patient's the ID of this supersonic diagnostic appts 1 imaging and the name (step S11) of patient P.User is selected therapeutic outcome deterministic model (step S12) by button 402 shown in Figure 3.After selected, supersonic diagnostic appts 1 (perhaps display device 14) requires user input picture title (or filename) so that in subsequent operation the view data that obtains is stored in use in the memorizer 24.For example, user operation input apparatus 13 input picture names " INJ-AFTER-1 " (step S13).
After the input picture title, the tabulation 42 of the image name (ID and the name imported among the corresponding patient P step S11) of view data is shown in as shown in Figure 6 the display device 14 before the treatment of patient P.View data is the view data that obtains before therapeutic treatment before the treatment, can be equivalent to " dynamic image data in past ".In tabulation 42, for example patient's ID and patient's name are shown in the top.The image name of view data also is listed in the tabulation 42 with its imaging date and time before the treatment.The described time can be the instantaneous time that the injection timer switch starts.User is selected the Image Name (step S14) of needs from listed Image Name.Though user may usually be selected a nearest view data according to date and time from tabulation, can select Image Name here is image as " INJ-1 ".
According to the Image Name that user is selected, " INJ-1 " by name and the view data that is stored in the memorizer 24 are presented in the display device 14.The view data of " INJ-1 " by name can be shown in the left side as display device 14 windows.The view data of " INJ-1 " by name can be duplicated by key shown in Figure 3 403 by user.After duplicating, the view data of " INJ-1 " by name can show with still image according to the initial frame of dynamic image at every turn.If user contact patient ultrasound probe 12 on one's body, current ultrasound image data can be shown in, for example, and display device 14 right side window.The view data (step S15) of " INJ-1 " by name that the user inspection shows, thereby the same image-forming condition that determines whether to be adapted at and be called the view data of " INJ-1 " shows the view data after the treatment down, and perhaps whether the image-forming condition (perhaps using other image-forming condition) of the treatment back view data that obtains can be better in the judgement change subsequent operation (step S16).View data after the treatment is the view data that obtains through after the treatment, can be equivalent to " present dynamic view data ".Usually can use same image-forming condition so that the view data before and after the treatment can be compared under the same conditions.Yet, if user be reluctant will the treatment of by name " INJ-1 " before the image-forming condition of the view data view data after being applied to treat, can change the image-forming condition (step S18) of treatment back view data so.
User begins to give (or injection) contrast agent (step S17) to patient P then.Almost in injection, user or its assistant open the injection timer switch, for example, open, by, select, input or click injection timer switch (step S19).
After the injection timer switch was opened, control appliance 23 control transmission and receiving equipment 21 made ultrasound probe 12 that ultrasonic signal is imported in patient's body.Ultrasonic signal returns with echo signal through human body.Echo signal is handled via echo signal processor 21 by transmission and receiving equipment 21 after ultrasonic probe 12 receives and converts the signal of telecommunication to.According to signal after treatment, become figure equipment 25 to form view data.Treatment back view data is presented at display device 14 right side window.Described view data can be the ultrasonography of contrast agent enhanced.Although this depends on image-forming condition, view data is real-time demonstration basically.
In display device 14, injection timer switch one is opened (step S19), and the view data of by name " INJ-1 " is also reproduced and be shown in the left window of display device 14.Therefore, the view data of " INJ-1 " by name, just, the view data before the treatment can show synchronously with the view data after the treatment basically.In some sense, though to time of the injection passage of view data before treating with may be variant slightly to the time for the treatment of the back passage, the lapse of time after the two corresponding injection timer is opened is synchronous.Therefore, user can be observed the enhancing process of contrast agent in the view data after the treatment that shows continuously, and compares with it and as view data enhancing process before the treatment of dynamic image demonstration.Show view data before and after the treatment if display device 14 can not walk abreast as single display device, view data may be displayed on another one and is connected in the display device of main equipment 11 as display device 14 parts before the treatment so.
For the view data after the treatment, after opening, the injection timer promptly begins to measure lapse of time.Because the unlatching (step S19) of injection timer is almost carried out simultaneously with the contrast agent start injection.Therefore lapse of time is the lapse of time after pointed injection begins basically.
Fig. 7 is the sketch map that the expression blood-vessel image shows comparison example.As shown in Figure 7, in the early stage enhancing process, the blood-vessel image of the view data of " INJ-1 " and " INJ-AFTER-1 " by name is presented in the window 43 of display device 14 after contrast-medium injection.In other words, display window 43 has shown that be 48 seconds treatment front and back image 431 and 432 time phase (or lapse of time).Can be the Image Name of image 431 and 432 step display S3 and S13 input.For image 431, imaging date and instantaneous time also can and Image Name " INJ-1 " show together.Lapse of time (for example, 48 seconds) of being measured by the injection timer also can be image 431 and 432 demonstrations.Shown in lapse of time of injecting separately after timer is opened of image 431 and 432 be synchronous.
Because image 431 and 432 is angiographys, so only be that blood-vessel image has strengthened in image 431 and 432.Each circle 412 and 431 is represented tumor locus.Because image 431 shows the tumor untreated, contrast agent flows into tumor by blood vessel, so observe enhanced blood-vessel image in circle 412.On the other hand, passed through therapeutic treatment because image 432 shows tumor, contrast agent can not flow into tumor by blood vessel, so do not observe enhanced blood-vessel image in circle 433.
Fig. 8 is the sketch map that the expression perfusion image shows comparison example.As shown in Figure 8, after contrast-medium injection, strengthen process late period, image " INJ-1 " by name and " perfusion image of the view data of INJ-AFTER-1 is shown in display device 14 windows 44.In other words, display window 44 has shown when time phase difference (or lapse of time) is 1 minute and 32 seconds the image 441 after treatment when image 411 before the treatment and time phase difference (or lapse of time) are 1 minute and 32 seconds.Be similar to display window 43, the step S3 and the image 411 of step S13 input and 441 Image Name can show respectively.For image 411, imaging date and instantaneous time also can and Image Name " INJ-1 " show together.Lapse of time (for example, 1 minute and 32 seconds) that image 411 and 441 injection timers are measured all can show.Shown in image 411 and 441 lapse of time after injecting timer separately and opening be synchronous.
Because image 411 and 441 is perfusion images, so the dash area representative strengthens part.So that contrast agent flows in the liver behind the blood capillary and tissue, the entire portion of view data all is enhanced and with the perfusion image data show through the long enough time.Because image 411 shows tumor without therapeutic treatment, contrast agent flows in the tumor, so the tumor section in the circle 412 is also used shadow representation by blood vessel and blood capillary.On the other hand, passed through therapeutic treatment because image 441 shows tumor, contrast agent can not flow into tumor by blood vessel, so the circle shadow representation in the circle 433.In other words, user is by observing enhanced blood vessel, blood capillary and organizing not appear at just can determine in the circle 433 to treat and succeed.
The treatment view data that obtains according to ultrasound signal transmission also is stored in the memorizer 24 with the view data of " INJ-AFTER-1 " by name.Instantaneous time, lapse of time and image-forming condition information when in addition, the injection timer switch is opened are also stored wherein together with view data after the above-mentioned treatment.
After finishing above imaging operation, user can be closed injection timer switch (step S20).After closing, the storage of view data and lapse of time information is also ended.The therapeutic outcome deterministic model is cancelled.
If desired same patient P is carried out similar Enhanced Imaging, but repeating step S12 to S20.
If user can be observed enhanced blood vessel, blood capillary and organize and still appear in the circle 433, can determine not success fully of therapeutic treatment so, patient P is carried out other therapeutic treatment.Image Name " INJ-AFTER-1 " can be joined in the tabulation shown in Figure 6 42, when user carries out next step operation of therapeutic outcome deterministic model, can in the selection course of step S14, it be selected to treat the Image Name of preceding view data as last that.
As mentioned above, user only needs (injection of contrast medium and) to open timer switch to compare the view data of observing after the treatment by the view data before the method for synchronization and the treatment.For example, blood-vessel image data, perfusion image data or the view data of phase place all can accurately contrast the view data before and after the treatment with the method for synchronization at an easy rate any time.
According to the embodiment of supersonic diagnostic appts, also can carry out following improvement.
Fig. 9 is the improved structure chart of expression supersonic diagnostic appts shown in Figure 1.As shown in Figure 9, supersonic diagnostic appts 1 can be electrically connected with outer injectors 90 by interface 26.This outer injectors can be independent of described supersonic diagnostic appts 1.When user was opened the injection timer switch in input equipment 13, the open command that control appliance 23 responses obtain was opened the injection timer.In addition, the open command of control appliance 23 response acquisitions offers outer injectors 90 by interface 26 with activation control signal.If outer injectors 90 has been ready to give the patient infusion contrast agent with pin, outer injectors 90 will the start injection contrast agent so.
Alternative, user can start outer injectors by operation outer injectors 90.The response start-up operation, outer injectors 90 can the start injection contrast agent.Outer injectors 90 also can offer control appliance 23 by interface 26 with enabled instruction according to start-up operation.Control appliance 23 can be opened the injection timer according to the open command of receiving from outer injectors 90.
In above-mentioned improvement, but injection of contrast medium and injection timer open single stepping and finish automatically, in input equipment 13, open the injection timer switch or open outer injectors 90.In addition, user does not need assistant's help.Therefore, may improve the synchronous accuracy of injection initial sum injection timer between beginning to measure.It also can reduce the operation of user.
The remaining operation of supersonic diagnostic appts 1 may be with shown in Fig. 1 similar.
The another one of embodiment is improved, one-tenth figure equipment 25 can be handled the view data before treating in advance, so that determine its luminance level (luminance level) and the time phase of the predetermined position determined (for example, certain section area-of-interest such as tumor locus) when luminance level reaches predetermined reference level by the contrast agent in the view data.Described predetermined reference level and lapse of time are equivalent to can be stored in the memorizer 24 time phase.During view data after showing treatment, one-tenth figure equipment 25 also can be handled the view data after the treatment, so that the contrast agent of the corresponding position by predetermined position determines whether luminance level has reached default reference levels.When determining that as figure equipment 25 luminance level has reached preset level, the view data before the treatment just can show from the time phase that stores, so that the view data before and after the treatment can the method for synchronization show.
Above-mentioned improvement only is an example.The Flame Image Process that can adopt any kind is to obtain synchronous demonstration.
The further improvement of embodiment also relates to the demonstration of one or more still images.Though in the above-described embodiment, dynamic image shows that as the view data before and after the treatment view data showed before one or more still images can be used as treatment.For example, one or more still images of special time phase place (time phase) can be before treatment original formation or by before dynamic treatment, extracting a frame the view data or multiframe forms as described still image in the Enhanced Imaging process.The still image that forms can be stored in the memorizer 24 together with lapse of time (or time phase) information.View data after the treatment is as in the dynamic image procedure for displaying, and the still image of storage can view data show after treatment corresponding time phase.In case a still image is shown, this width of cloth image will be shown for a moment.For example, this still image can show default a period of time or continue to be shown to next still image.
The embodiment of the invention described above only is to be used for allowing the people be more readily understood the description of example of the present invention, rather than to the description of the present invention restriction.Therefore, disclosed each equipment all can redesign or change into its equivalent within the scope of the present invention with element in the embodiment of the present invention.And as long as advantage is similar to the advantage that obtains in the embodiment of the present invention foregoing description, any possible combination of the said equipment and element includes in category of the present invention.
According to top instruction, can carry out a large amount of changes and change to the present invention.Therefore, be appreciated that unless otherwise specified, the present invention all can implement within the scope of claim in the back.

Claims (39)

1. supersonic diagnostic appts comprises:
Be used for ultrasound signal transmission to the position of sample and the transceiver of the echo signal that obtains of received ultrasonic signal transmission, this position is by injection of contrast medium;
The processor for preparing dynamic image data according to the echo signal of receiving;
Store the memorizer of the dynamic image data of preparation as the past dynamic image data; With
The past of the parallel preparation of video-stream processor and the display device of current dynamic image data, response is used for the beginning of current dynamic image data contrast-medium injection, and the past dynamic image data is shown.
2. device according to claim 1, wherein memorizer also is used to store and the first relevant image-forming condition of past dynamic image data.
3. device according to claim 2 also comprises control appliance, is used for comparison first image-forming condition and second image-forming condition relevant with current dynamic image data, and according to the comparative result control device.
4. device according to claim 1 also comprises the injection timer that is used to measure injection beginning back lapse of time, and wherein memorizer also is used to store lapse of time information relevant with the past dynamic image data of mensuration.
5. device according to claim 1, also comprise the injection timer of measuring injection beginning back lapse of time, when wherein display device showed past and present dynamic view data, display device showed the past dynamic image data with respect to lapse of time and current dynamic image data basic synchronization.
6. device according to claim 1, also comprise the input equipment that is used to import instruction, wherein memorizer also is used to store and the relevant instantaneous time information of past dynamic image data, display device also is used to show the tabulation of instantaneous time information of the past dynamic image data of storage, and shows and the corresponding dynamic image data of time prompting message by instruction storage of selection from tabulation.
7. device according to claim 1, wherein passing by dynamic image data is to form according to the echo signal that the position on the sample is carried out receive before the therapeutic treatment, and current dynamic image data then is to form according to the echo signal of receiving behind the therapeutic treatment.
8. device according to claim 1, wherein this position of sample comprises the liver position.
9. device according to claim 1 also comprises the input equipment that is used to import the injection sign on, is used to measure the injection timer of injection beginning back lapse of time; And be used for injecting the control appliance that timer begins to measure according to instruction control.
10. device according to claim 9, wherein control appliance also is used for providing instruction so that the syringe start injection to the outer injectors that is connected with device.
11. device according to claim 1 also comprises being used for device is connected in outer injectors and injects the interface of sign on from the outer injectors reception; Be used to measure the injection timer of injection beginning back lapse of time; Be used for injecting the control appliance that timer begins to measure according to the instruction control that receives.
12. device according to claim 1 also comprises second processor that is used for dynamic image data is carried out Flame Image Process, wherein injection begins to determine according to Flame Image Process.
13. a supersonic diagnostic appts comprises:
To the position of sample and the transceiver of received ultrasonic signal transmission result's echo signal, this position is by injection of contrast medium with ultrasound signal transmission;
The processor for preparing view data according to the echo signal of receiving;
To the memorizer of at least one image storage view data as the past view data; With
The past of the parallel preparation of video-stream processor and the display device of current images data, according to from being used for the time phase of the current image date that the current image date contrast-medium injection begins, the view data in past is shown.
14. device according to claim 13 wherein passes by view data to show as at least one width of cloth still image.
15. device according to claim 13, wherein view data comprises dynamic image data, and view data forms according to dynamic image data in the past.
16. device according to claim 13, wherein view data comprises dynamic image data, and current image date comprises dynamic image data.
17. device according to claim 13, wherein memorizer also is used to store and the first relevant image-forming condition of past view data.
18. device according to claim 17 also comprises control appliance, is used for comparison first image-forming condition and the second time image-forming condition relevant with current image date, and according to the comparative result control device.
19. device according to claim 13 also comprises the injection timer, measures the lapse of time after injection begins, wherein memorizer also is used for the information of lapse of time relevant with the past view data of storing measurement.
20. device according to claim 13, also comprise the injection timer that is used to measure injection beginning back lapse of time, when wherein display device showed past and current image date, display device showed view data in the past with respect to lapse of time and current image date basic synchronization ground.
21. device according to claim 13, also comprise the input equipment that is used to import instruction, wherein memorizer also is used to store and the relevant instantaneous time information of past view data, display device also is used to show the instantaneous time information list of the past view data of storage, and shows and institute's instantaneous time information of depositing view data of corresponding past of choosing from tabulation by instruction.
22. device according to claim 13, wherein passing by view data is to form according to the echo signal that sample site is carried out receive before the therapeutic treatment, and current image date then is to form according to the echo signal of receiving behind the therapeutic treatment.
23. device according to claim 13, wherein this position of sample comprises the part of liver.
24., also comprise the input equipment that is used to import the injection sign on according to claim 13; Measure the injection timer of injection beginning back lapse of time; And according to instructing control injection timer so that the control appliance that begins to measure.
25. device according to claim 24, wherein said control appliance also are used for providing instruction so that the syringe start injection to the outer injectors that links to each other with device.
26. device according to claim 13 also comprises connecting device and outer injectors and the interface that receives the start injection instruction from outer injectors; Measure the injection timer of injection beginning back lapse of time; Inject timer so that the control appliance that begins to measure according to the instruction control that receives.
27. device according to claim 13 also comprises second processor that is used for view data is carried out Flame Image Process, wherein injection begins to determine according to Flame Image Process.
28. a method that shows the ultrasonography that supersonic diagnostic appts obtains, this method comprises:
To the position of sample and receive first echo signal that obtains from first ultrasound signal transmission, first contrast agent is injected at this position with first ultrasound signal transmission;
Form first dynamic image data according to first echo signal of receiving;
Store formed first dynamic image data as the past dynamic image data;
To this position of sample and receive second echo signal that obtains from second ultrasound signal transmission, second contrast agent is injected at this position with second ultrasound signal transmission;
Form second dynamic image data according to second echo signal of receiving; And
The parallel past dynamic image data and second dynamic image data of showing is as ultrasonoscopy, and response is used for the beginning of the contrast-medium injection of current dynamic image data, and the past dynamic image data is shown.
29. method according to claim 28 also comprises storing and the first relevant image-forming condition of past dynamic image data.
30. method according to claim 29 also comprises first image-forming condition is compared with second image-forming condition relevant with second dynamic image data, according to the comparative result control device.
31. method according to claim 28 also comprises lapse of time of measuring after injection begins, and stores lapse of time information of measuring relevant with the past dynamic image data.
32. method according to claim 28, also comprise lapse of time of measuring after injection begins, and when showing the past dynamic image data and second dynamic image data, show dynamic image data in the past with respect to lapse of time and second dynamic image data basic synchronization ground.
33. method according to claim 28, also comprise the input instruction, store and the relevant instantaneous time information of past dynamic image data, show the tabulation of the instantaneous time information of stored past dynamic image data, and show and institute's instantaneous time information of depositing dynamic image data of corresponding past of from tabulation, choosing according to instruction.
34. method according to claim 28, wherein passing by dynamic image data is to form according to the echo signal that this position of sample is accepted to receive before the therapeutic treatment, and second dynamic image data then is to form according to the echo signal of receiving behind the therapeutic treatment.
35. method according to claim 28, wherein this position of sample comprises the part of liver.
36. method according to claim 28 also comprises the instruction of input injection beginning; Measure the lapse of time after injection begins; And control beginning according to instruction and to measure.
37. method according to claim 36 also comprises to the outer injectors that links to each other with device providing instruction so that start injection.
38. method according to claim 28 also comprises the instruction that receives the injection beginning from the outer injectors that links to each other with device; Measure the lapse of time after injection begins; The instruction that response receives is controlled to begin mensuration.
39. method according to claim 28 also comprises the past and second dynamic image data are carried out Flame Image Process, wherein injection begins to determine according to Flame Image Process.
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