CN1612856A - 1,3-二芳基丙-2-烯-1-酮、含有它们的组合物及其用途 - Google Patents
1,3-二芳基丙-2-烯-1-酮、含有它们的组合物及其用途 Download PDFInfo
- Publication number
- CN1612856A CN1612856A CNA028268601A CN02826860A CN1612856A CN 1612856 A CN1612856 A CN 1612856A CN A028268601 A CNA028268601 A CN A028268601A CN 02826860 A CN02826860 A CN 02826860A CN 1612856 A CN1612856 A CN 1612856A
- Authority
- CN
- China
- Prior art keywords
- propenone
- amino
- methoxy
- methyl
- trimethoxyphenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
- C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/22—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/30—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to nitro or nitroso groups
- C07C279/32—N-nitroguanidines
- C07C279/36—Substituted N-nitroguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Bending Of Plates, Rods, And Pipes (AREA)
- Detergent Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Indole Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0115739A FR2833008B1 (fr) | 2001-12-05 | 2001-12-05 | 1,3-diarylprop-2-en-1-ones, compositions les contenant et utilisation |
FR01/15739 | 2001-12-05 | ||
FR02/14217 | 2002-11-14 | ||
FR0214217 | 2002-11-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN1612856A true CN1612856A (zh) | 2005-05-04 |
Family
ID=26213287
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA028268601A Pending CN1612856A (zh) | 2001-12-05 | 2002-12-03 | 1,3-二芳基丙-2-烯-1-酮、含有它们的组合物及其用途 |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP1453790A2 (fr) |
JP (1) | JP2005531494A (fr) |
KR (1) | KR20050044712A (fr) |
CN (1) | CN1612856A (fr) |
AR (1) | AR037479A1 (fr) |
AU (1) | AU2002365644A1 (fr) |
BR (1) | BR0214694A (fr) |
CA (1) | CA2469193A1 (fr) |
CO (1) | CO5580759A2 (fr) |
EA (1) | EA006803B1 (fr) |
HR (1) | HRP20040508A2 (fr) |
HU (1) | HUP0500100A2 (fr) |
IL (1) | IL162223A0 (fr) |
MA (1) | MA27351A1 (fr) |
MX (1) | MXPA04005226A (fr) |
NZ (1) | NZ533224A (fr) |
PA (1) | PA8558501A1 (fr) |
PE (1) | PE20030758A1 (fr) |
PL (1) | PL370676A1 (fr) |
RS (1) | RS47804A (fr) |
SV (1) | SV2003001422A (fr) |
TW (1) | TW200300685A (fr) |
WO (1) | WO2003048106A2 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109467549A (zh) * | 2018-12-07 | 2019-03-15 | 中国药科大学 | 喹啉取代查尔酮类化合物、其制备方法及用途 |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2854399B1 (fr) * | 2003-04-30 | 2006-11-17 | Aventis Pharma Sa | 1-aryl-3-(indol-5-yl)-prop-2-en-1-ones, compositions les contenant et utilisation |
EP1598353A1 (fr) * | 2004-05-17 | 2005-11-23 | Boehringer Ingelheim International GmbH | Pyrrolobenzimidazolones et leur utilisation en tant qu'agents antiproliferatifs |
WO2017103637A1 (fr) | 2015-12-18 | 2017-06-22 | Blirt S.A. | Composés de diphénylpropane et leur activité cytotoxique |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4904697A (en) * | 1987-04-09 | 1990-02-27 | Merrell Dow Pharmaceuticals Inc. | Controlling the growth of certain tumor tissue with chalcone derivatives |
JPH08277242A (ja) * | 1995-02-08 | 1996-10-22 | Kyowa Hakko Kogyo Co Ltd | プロペノン誘導体 |
ATE259353T1 (de) * | 1995-12-01 | 2004-02-15 | Kyowa Hakko Kogyo Kk | Propenonderivate |
WO1999000114A2 (fr) * | 1997-06-26 | 1999-01-07 | Statens Serum Institut | 1,3-bis-aromatique-prop-2-en-1-ones, 1,3-bis-aromatique-propane-1-ones et 1,3-bis-aromatique-prop-2-yn-1-ones a action biologique |
-
2002
- 2002-11-21 PE PE2002001118A patent/PE20030758A1/es not_active Application Discontinuation
- 2002-11-22 PA PA20028558501A patent/PA8558501A1/es unknown
- 2002-11-26 TW TW091134346A patent/TW200300685A/zh unknown
- 2002-11-29 AR ARP020104618A patent/AR037479A1/es unknown
- 2002-12-02 SV SV2002001422A patent/SV2003001422A/es not_active Application Discontinuation
- 2002-12-03 IL IL16222302A patent/IL162223A0/xx unknown
- 2002-12-03 AU AU2002365644A patent/AU2002365644A1/en not_active Abandoned
- 2002-12-03 EP EP02804242A patent/EP1453790A2/fr not_active Withdrawn
- 2002-12-03 MX MXPA04005226A patent/MXPA04005226A/es unknown
- 2002-12-03 HU HU0500100A patent/HUP0500100A2/hu unknown
- 2002-12-03 PL PL02370676A patent/PL370676A1/xx unknown
- 2002-12-03 CA CA002469193A patent/CA2469193A1/fr not_active Abandoned
- 2002-12-03 EA EA200400764A patent/EA006803B1/ru not_active IP Right Cessation
- 2002-12-03 RS YU47804A patent/RS47804A/sr unknown
- 2002-12-03 BR BR0214694-0A patent/BR0214694A/pt not_active IP Right Cessation
- 2002-12-03 CN CNA028268601A patent/CN1612856A/zh active Pending
- 2002-12-03 NZ NZ533224A patent/NZ533224A/xx unknown
- 2002-12-03 JP JP2003549299A patent/JP2005531494A/ja not_active Abandoned
- 2002-12-03 WO PCT/FR2002/004143 patent/WO2003048106A2/fr not_active Application Discontinuation
- 2002-12-03 KR KR1020047008656A patent/KR20050044712A/ko not_active Application Discontinuation
-
2004
- 2004-06-01 MA MA27708A patent/MA27351A1/fr unknown
- 2004-06-03 CO CO04052091A patent/CO5580759A2/es not_active Application Discontinuation
- 2004-06-04 HR HR20040508A patent/HRP20040508A2/hr not_active Application Discontinuation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109467549A (zh) * | 2018-12-07 | 2019-03-15 | 中国药科大学 | 喹啉取代查尔酮类化合物、其制备方法及用途 |
CN109467549B (zh) * | 2018-12-07 | 2021-02-09 | 中国药科大学 | 喹啉取代查尔酮类化合物、其制备方法及用途 |
Also Published As
Publication number | Publication date |
---|---|
BR0214694A (pt) | 2004-12-14 |
IL162223A0 (en) | 2005-11-20 |
SV2003001422A (es) | 2003-07-10 |
PE20030758A1 (es) | 2003-10-07 |
PA8558501A1 (es) | 2003-09-05 |
PL370676A1 (en) | 2005-05-30 |
HRP20040508A2 (en) | 2005-08-31 |
AR037479A1 (es) | 2004-11-10 |
WO2003048106A3 (fr) | 2004-03-25 |
EA200400764A1 (ru) | 2004-12-30 |
MA27351A1 (fr) | 2005-06-01 |
CO5580759A2 (es) | 2005-11-30 |
RS47804A (en) | 2006-12-15 |
HUP0500100A2 (hu) | 2005-05-30 |
NZ533224A (en) | 2006-03-31 |
EA006803B1 (ru) | 2006-04-28 |
AU2002365644A1 (en) | 2003-06-17 |
KR20050044712A (ko) | 2005-05-12 |
TW200300685A (en) | 2003-06-16 |
WO2003048106A2 (fr) | 2003-06-12 |
JP2005531494A (ja) | 2005-10-20 |
MXPA04005226A (es) | 2004-10-11 |
CA2469193A1 (fr) | 2003-06-12 |
EP1453790A2 (fr) | 2004-09-08 |
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