CN1561208A - 活化祖细胞/干细胞的方法 - Google Patents
活化祖细胞/干细胞的方法 Download PDFInfo
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- CN1561208A CN1561208A CNA028149955A CN02814995A CN1561208A CN 1561208 A CN1561208 A CN 1561208A CN A028149955 A CNA028149955 A CN A028149955A CN 02814995 A CN02814995 A CN 02814995A CN 1561208 A CN1561208 A CN 1561208A
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- cfu
- pyridylmethyl
- tetrahydrochysene
- stem cell
- benzene dimethylamine
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Abstract
Description
每毫升血液的绝对祖细胞数甲基纤维素培养基 | |
CFU-GM BFU-E CFU-GEMM | |
对照AMD3100:15″AMD3100:30″AMD3100:120″ | 289.8 49.4 25.8791.6 134.5 90.41805.5 209.3 113.5828.7 102.3 47.6 |
每毫升血液的绝对祖细胞数甲基纤维素培养基 | |
CFU-GM BFU-E CFU-GEMM | |
盐水AMD3100:10mg/kgAMD3100:5mg/kgAMD3100:2.5mg/kgAMD3100:1mg/kg | 188.1 16 19825.6 120.5 79.8608.4 92.8 69.5687.6 98.9 70.6424 62 27.1 |
细胞数甲基纤维素培养基 | |
时间15″30″2′ | GM BFU-E CFU-GEMM |
2.73 2.72 3.516.23 4.24 4.412.86 2.07 1.85 |
ID | 筛 | 基线 | 处理 | ||||||
30分钟 | 1Hr | 2Hr | 4Hr | 6Hr | 9Hr | Day2 | |||
P1 | 7.4 | 6.41 | 8.02 | 14.8 | 21.4 | 23.2 | 26.2 | 22.3 | 7.07 |
P2 | 6.04 | 5.45 | 6.53 | 8.93 | 13.5 | 18.00 | 19.2 | 19.6 | 8.03 |
P3 | 4.38 | 5.8 | 7.14 | 9.28 | ND | 18.10 | 17.9 | 18.4 | 4.98 |
P4 | 5.08 | 5.31 | 4.37 | 7.38 | 12.4 | 14.6 | 15.8 | 13.9 | 4.98 |
P5 | 4.53 | 5.02 | 6.08 | 8.43 | ND | 16.90 | 19.3 | 19.00 | 4.57 |
ID | 基线 | 处理 | ||||
1Hr | 3Hr | 6Hr | 9Hr | Day2 | ||
P1 | .07 | .04 | .07 | .11 | .11 | .08 |
P2 | .08 | .06 | .08 | .13 | .11 | .12 |
P3 | .07 | .16 | .06 | ND | .11 | .07 |
P4 | .05 | .07 | .09 | .09 | .1 | .1 |
P5 | .12 | .12 | .13 | .2 | .2 | .16 |
有核细胞结构 | ||
PBL-US | PBL-LD | |
MEAN STD STE %CHG P | MEAN STD STE %CHG P | |
T=0T=1T=3T=6T=9T=24 | 1.00 0.00 0.00 0.0%1.69 0.00 0.00 68.6% 0.0172.80 0.51 0.23 180.2% 0.0003.26 0.61 0.27 225.8% 0.0003.09 0.69 0.31 209.4% 0.0001.07 0.65 0.29 7.0% 0.553 | 1.00 0.00 0.00 0.0%1.86 0.00 0.00 86.2% 0.0002.86 0.28 0.12 185.6% 0.0003.66 0.43 0.19 266.3% 0.0013.64 1.18 0.53 264.3% 0.0011.05 1.19 0.53 4.6% 0.815 |
甲基纤维素培养基 | |||
CFU-GM | BFU-E | CFU-GEMM | |
MEAN STD STE %CHG P | MEAN STD STE %CHG P | MEAN STD STE %CHG P | |
T=0T=1T=3T=6T=9T=24 | 1.00 0.00 0.00 0.0%4.77 0.00 0.00 376.7% 0.00113.66 1.56 0.70 1266.5% 0.00121.71 5.78 2.58 2070.6% 0.00010.47 5.09 2.28 947.3% 0.0001.56 3.01 1.34 55.5 0.005 | 1.00 0.00 0.00 0.0%1.99 0.00 0.00 98.9% 0.0023.21 0.50 0.22 221.3% 0.0046.01 1.25 0.56 500.5% 0.0064.34 2.99 1.34 334.4% 0.0001.26 1.02 0.46 26.3% 0.194 | 1.00 0.00 0.00 0.0%2.32 0.00 0.00 131.8% 0.0004.33 0.44 0.20 332.5% 0.00010.07 0.59 0.27 907.2% 0.0025.25 4.54 2.03 425.4% 0.0141.53 3.04 1.36 53.2% 0.199 |
琼脂培养基 | |
MEAN STD STE %CHG P | |
T=0T=1T=3T=6T=9T=24 | 1.00 0.00 0.00 0.0%2.81 0.00 0.00 180.8% 0.0018.54 0.75 0.34 754.1% 0.00017.93 1.62 0.72 1692.8% 0.00010.25 4.57 2.04 924.9% 0.0002.08 2.06 1.03 108.3% 0.073 |
有核细胞结构 | ||
PBL-US | PBL-LD | |
P1 P2 P3 P4 P5 | P1 P2 P3 P4 P5 | |
T=0T=1T=3T=6T=9T=24 | 1.00 1.00 1.00 1.00 1.002.54 1.38 1.38 1.36 1.763.55 2.74 2.02 2.46 3.233.97 2.94 2.74 2.60 4.043.27 3.30 2.69 2.24 3.961.21 1.43 0.96 0.77 0.99 | 1.00 1.00 1.00 1.00 1.002.07 1.99 1.48 1.66 2.102.83 3.25 2.17 2.82 3.204.07 3.90 2.27 2.78 5.303.05 4.43 2.47 2.48 5.171.01 1.71 0.79 0.60 1.12 |
甲基纤维素培养基 | |||
CFU-GM | BFU-E | CFU-GEMM | |
P1 P2 P3 P4 P5 | P1 P2 P3 P4 P5 | P1 P2 P3 P4 P5 | |
T=0T=1T=3T=6T=9T=24 | 1.00 1.00 1.00 1.00 1.005.09 5.33 3.70 6.87 2.847.12 17.02 15.07 20.72 8.4014.66 23.96 20.99 28.54 20.396.26 12.51 9.42 14.08 10.091.10 1.91 1.43 1.51 1.83 | 1.00 1.00 1.00 1.00 1.002.58 1.48 2.30 1.46 2.135.13 1.98 2.61 2.60 3.759.14 3.67 4.54 3.34 9.355.43 4.61 3.71 2.93 5.051.06 1.88 1.14 0.79 1.44 | 1.00 1.00 1.00 1.00 1.002.07 2.26 2.22 1.96 3.074.25 3.47 4.34 5.14 4.437.47 9.35 6.52 9.10 17.922.64 7.09 2.47 4.52 9.551.12 2.62 0.69 0.98 2.25 |
琼脂培养基CFU-GM | |
P1 P2 P3 P4 P5 | |
T=0T=1T=3T=6T=9T=24 | 1.00 1.00 1.00 1.00 1.003.05 3.74 1.67 2.71 2.878.88 9.49 7.47 10.46 6.4017.77 24.01 14.04 13.07 20.7510.28 7.72 10.22 12.783.69 1.13 1.30 2.20 |
CFU-GM | BFU-EP1 | CFU-GEMM | CFU-GM | BFU-EP2 | CFU-GEMM | |||||||
每毫升的绝对祖细胞数 | 祖细胞的循环状态 | 每毫升的绝对祖细胞数 | 祖细胞的循环状态 | 每毫升的绝对祖细胞数 | 祖细胞的循环状态 | 每毫升的绝对祖细胞数 | 祖细胞的循环状态 | 每毫升的绝对祖细胞数 | 祖细胞的循环状态 | 每毫升的绝对祖细胞数 | 祖细胞的循环状态 | |
T=0T=1T=3T=6T=9T=24 | 2471259176036241547271 | 6%1%1%0%2%0% | 261674134023881418278 | 0%0%13%0%11%0% | 127264540949335142 | 6%0%7%0%0%0% | 2731455464665403416521 | 0%0%2%0%0%3% | 41060880915021886768 | 2%3%0%0%0%2% | 1202724181126854316 | 0%6%0%0%4%0% |
CFU-GM | BFU-EP3 | CFU-GEMM | CFU-GM | BFU-EP4 | CFU-GEMM | |||||||
每毫升的绝对祖细胞数 | 祖细胞的循环状态 | 每毫升的绝对祖细胞数 | 祖细胞的循环状态 | 每毫升的绝对祖细胞数 | 祖细胞的循环状态 | 每毫升的绝对祖细胞数 | 祖细胞的循环状态 | 每毫升的绝对祖细胞数 | 祖细胞的循环状态 | 每毫升的绝对祖细胞数 | 祖细胞的循环状态 | |
T=0T=1T=3T=6T=9T=24 | 2811040423358952647402 | 0%0%1%0%0%0% | 35180891515931302402 | 0%0%0%0%0%0% | 14031261091634797 | 0%0%0%0%0%0% | 138947285739361942208 | 0%0%5%0%0%5% | 460672119515331348362 | 0%0%9%0%0%3% | 10119951992045799 | 0%0%0%8%0%0% |
CFU-GM | BFU-EP5 | CFU-GEMM | ||||
每毫升的绝对祖细胞数 | 祖细胞的循环状态 | 每毫升的绝对祖细胞数 | 祖细胞的循环状态 | 每毫升的绝对祖细胞数 | 祖细胞的循环状态 | |
T=0T=1T=3T=6T=9T=24 | 169481142334541710310 | 0%0%5%0%0%0% | 343730128832081731495 | 1%0%3%1%0%0% | 55169244987526124 | 0%0%0%0%0%0% |
琼脂培养基CFU-GM | 琼脂培养基CFU-GM | 琼脂培养基CFU-GM | 琼脂培养基CFU-GM | 琼脂培养基CFU-GM | |
P1 | P2 | P3 | P4 | P5 | |
每毫升 祖细胞的绝对 的循环祖细胞 状态数 | 每毫升 祖细胞的绝对 的循环祖细胞 状态数 | 每毫升 祖细胞的绝对 的循环祖细胞 状态数 | 每毫升 祖细胞的绝对 的循环祖细胞 状态数 | 每毫升 祖细胞的绝对 的循环祖细胞 状态数 | |
T=0T=1T=3T=6T=9T=24 | 233 6%710 0%2070 0%4142 0% | 100 0%376 0%953 12409 31032 0%371 0% | 140 0%234 0%1049 0%1972 31085 0%159 0% | 124 0%336 0%1299 0%1623 0%1268 0%162 0% | 104 0%298 3664 0%2153 11326 0%229 0% |
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DE102014206089B4 (de) | 2014-03-31 | 2018-01-18 | BSH Hausgeräte GmbH | Haushaltskältegerät mit einer Spendereinheit mit zwei Verschlusselementen an einem Ausführkanal |
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