CN1528349A - Health-care medicinal composition, and preparing method and use thereof - Google Patents
Health-care medicinal composition, and preparing method and use thereof Download PDFInfo
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Abstract
The present invention provides a health-care medicine composition and its preparation method. Said method includes the following steps: making photosynthetic bacterial pool, Chinese herbal medicine liquor, mineral solution and honey undergo the process of biological fermentation, then making them be combined with lactic acid microbial pool, yeast microbial pool, Cram-positive actinomycetes bacterial pool and filamentous microbial pool of fermentation line to form five family microbial community to obtain mother culture, then making said mother culture and nucleic acid, vitamin, SOD and amino acid undergo the process of biological emulsification so as to obtain the invented composition. Said composition has extensive application in preparation of medicine for curing broad-spectrum bacterial disease, broad-spectrum viral disease, damaged gene and diseases due to damaged cell, and specially for preventing and curing SARS.
Description
Technical field
The present invention relates to a kind of health medicine composition and method of making the same and purposes, belong to the health care field of medicaments.
Background technology
Propolis (Propolis) is the complex compound that plant genetic material and Apis endocrine etc. mix, a kind of colloidal solid thing that more strongly adherent, brownish black is arranged, have aromatic odor that to be Apis gather resin and sneak into that its mandibular gland secretions and Cera Flava etc. process from plant plumule and trunk, has extremely precious, extremely effective health keeping and medical function, energy overall regulating immunity of organism function, the enhancing body resist ability can prevent the generation of various complication; When giving human body with vigor and energy, the energy cell activity enhancing improves cell function, delaying cell aging, and strengthening immune system improves human body premunition and vis medicatrix naturae, makes human body energetic, and health is stayed forever.
Propolis is a kind of broad-spectrum antibiotic of pure natural, has complicated chemical constituent, comprising the trace element of more than 30 kind of needed by human such as more than 30 kinds of aromatic esters, more than 30 kind of chromocor compound (comprising flavone, flavonol and flavonol) and selenium, calcium, zinc, ferrum, copper, chromium, lithium, strontium, magnesium, 20 several amino acids; Kind of aromatic acid, Cera Flava acids, terpenoid, fatty acid surplus in the of ten; Several steroid class, alcohols, aldehydes, saccharide and ketone compounds; The organic compound that also has multiple phenols, black class, enzyme, vitamin, alkene, hydrocarbon and other biologically active.
The maximum characteristics of propolis are to contain abundant flavonoid and terpenoid substance, and flavone is one of nutrient of needed by human, can not synthesize in the body, can only absorb from food, to regulating physiological function, improve the life movement quality, are extremely important.
The main biological action and the effect of propolis can reduce the following aspects:
Can help blood sugar lowering, blood fat, vessel softening is regulated sugar, fat, proteinic metabolism proportionality action.
Enhance SOD activity is eliminated free radical, prevents lipid oxidation, and the protection beta Cell of islet is avoided free radical and attacked.
Make damaged cell regeneration, be beneficial to the cytothesis of loss, particularly can promote the reparation of islet cells, recover islet function.
The Radix Astragali, the original name Radix Astragali is the pulse family herbaceos perennial, medicinal its root is ancient simply Chinese medicine, is described as to control the rare medicinal herbs of mending two benefits.According to the Compendium of Material Medica record, Radix Astragali sweet in the mouth is warm in nature, goes into spleen, lung meridian, the merit of tool invigorating QI to consolidate the body surface resistance diuretic, nourishing blood and promoting granulation poison holding.For anemia, edema, body empty hyperhidrosis, frequent fetal movement, uterine prolapse, deficiency of both QI and blood, know empty deficiency etc. well, distinguished curative effect is all arranged.Modern science is analyzed, the multiple compositions such as selenium, silicon that contain polysaccharide, monosaccharide, flavonoid, alkaloid (choline, betanin), folic acid, several amino acids, phlegmatic temperament, natural gum, cellulose and trace in the Radix Astragali, can improve cardio-pulmonary function, strengthen cardiac contractile force, blood vessel dilating, bring high blood pressure down, improve cutaneous circulation and nutriture; And the energy the liver protecting, prevent that liver glycogen from reducing, and to chronic active hepatitis, has good action.Pharmacological research proves that the effect that the Radix Astragali also has inducement interferon and transfers body's immunity can suppress virus breeding and tumor growth.
Ganoderma claims Ganoderma lucisum, Ganoderma Lucidum and Ganoderma lucidum seu Japonicum again, is Basidiomycetes, Aphyllophorales, Polyporaceae, Ganoderma; But hyoscine in the Shennong's Herbal of the Eastern Han Dynasty was classified Ganoderma as top gradely before bimillennium, think " food for a long time, it is not old to make light of one's life by commiting suicide, the angle prolongs life ".The Compendium of Material Medica record: Ganoderma bitter in the mouth, flat, nontoxic, the beneficial motive is invigorated blood circulation, and goes into heart hyperemia, helps the heart to fill arteries and veins, calm the nerves, lung benefiting gas, tonifying liver gas, invigorating middle warmer increases wisdom, good color, sharp joint, hard muscles and bones is eliminated the phlegm, and is good for the stomach.Be considered as strengthening by means of tonics for a long time always, consolidate the precious Chinese herbal medicine of setting upright.Modern medicine proves: body immunity can be regulated, be strengthened to Ganoderma, and neurasthenia, rheumatic arthritis, coronary heart disease, hypertension, hepatitis, diabetes, tumor etc. are had good synergistic therapeutic action.Current research shows: Ganoderma also has resisting fatigue, looks improving and the skin nourishing, and slow down aging is prevented and treated effects such as AIDS.
Selenium is one of most important element in the life sciences, is the necessary trace element of human body.Major function is an antioxidation, regulates immunologic function, removes free radical, is one of necessary nutrition of the definite human body of the United Nations's health organization.
Selenium is to constitute important essential compositions such as glutathion peroxidase and nicotinic acid hydroxylase.Glutathion peroxidase can become oxidized form of glutathione by the catalytic reduction glutathion; prevent macromole generation response to oxidative stress simultaneously; make the deleterious peroxide of body is reduced into harmless hydroxy compounds; and make hydrogen peroxide decomposes; thereby can protect the 26S Proteasome Structure and Function of cell membrane, make it not to be subjected to the infringement and the interference of peroxide.Scarce selenium will cause cell and membrane structure and function damage, and then the synthetic and metabolism of interfere RNA, protein, mucopolysaccharide and enzyme, directly influences division, breeding, heredity and the growth of cell.Selenium can play synergism with vitamin E, strengthens the vitamin E antioxidation, removes free radical, defying age.Vitamin E can protect prostacyclin sample material not to be subjected to the lipid peroxide function influence, and here selenium plays positive synergism.
But some enzyme of selenium activated lymphocyte, thereby strengthen lymphocytic antitumaous effect.
Selenium energy immune stimulatory globulin and production of antibodies, enhancing body is to the resistance of disease.Scarce selenium can cause neutrophil lethality to be reduced, and the antigen titration degree reduces and postpone the phenomenon of humoral immunization.After replenishing enough selenium, immunologic function improves.
Because selenic biological half-life is 11 days, its metabolism is quite fast.Along with selenic continuous absorption, also constantly discharge, zoopery shows that also the selenium supplement person's of stopping blood Se content can descend gradually, and tumor incidence rises gradually.So essential in life constantly Selenium Supplement is replenished the part of its loss, keeps the interior selenic healthy amount of body, to reach the effect of defying age and life lengthening.
Superoxide dismutase (Superoxide Dismutase) is called for short SOD, is a kind of metallic enzyme, and major function is that Radical Metabolism unnecessary in the human body is become innocuous substance.Be mainly used in delaying human body caducity at present clinically, the anti-pigmentation that goes up is eliminated local inflammation, particularly treat the inflammation behind rheumatic arthritis, chronic polyarthritis and the radiotherapy, no antigen, toxic and side effects is less, is the treatment enzyme that clinical value is arranged very much.
Vitamin A is to duplicate the necessary nutrient of body, and it can keep vision, keeps normal vision in the dim light; Can promote growth, keep the normal function of epithelial tissue cell, promote the growth promoter of skeleton, tooth and body, can guarantee the concentration and the vigor of sperm, guarantee to suppress the generation of active oxygen, remove free radical, slow down aging prevents that the tumor of cardiovascular and cerebrovascular disease from taking place.Vitamin A has the coenzyme effect, is the mediator of cholesterol synthetic hormone and glycoprotein building-up process.Vitamin A promotes cell proliferation and new direction differentiation by the effect to DNA and RNA.Vitamin A directly participates in proteinic synthetic.
Vitamin C claims ascorbic acid again, and the C that is deficient in vitamin can cause vitamin C deficiency.Vitamin C can promote the biosynthesis of collagen, helps the healing of wound mouth.Vitamin C can promote the growth of skeleton and tooth, increases the tube wall strength of blood capillary, the oozing phenomenon of avoiding skeleton and around teeth to occur.Vitamin C can promote the metabolism of tyrosine and tryptophan, quickens the deaminizating metabolism of albumen and peptide class.Vitamin C is the auxiliary passivation factor of fat hydrolase in the fattiness tissue with ATP, magnesium ion, and the free fatty that this enzyme hydrolysis fatty acid produces is the direct sources of human body energy.After energy satisfied, vitamin C and ATP and magnesium ion one this enzyme of passivation that works was in order to avoid fatty excessive hydrolysis.Vitamin C can the hardened generation of prevention of arterial.Vitamin C can be separated the toxicity of removing heavy metals or Toxic, and it is external to impel toxicity to get rid of, and particularly it can promote that ferrum enters haem gene, then, becomes a proteinic part, can finish the detoxifcation task thus.
Vitamin E is a kind of powerful antioxidant; it is free radical scavenger important in the Living organism; can protect on the body tissue cell biological film unsaturated fatty acid to exempt from attacks and oxidation; also protecting simultaneously macromolecular substances DNA to exempt from free radical destroys; also be the patron saint of cell, preventing old and feeble and preventing to play an important role aspect the tumor.
Vitamin E and selenium are collaborative, and the strength of huge elimination free radical is arranged, and close conspiracy relation is also arranged between them for this reason.Vitamin E can be protected and attacked and the peroxide injury that occurs by free radical, and selenium is then by destroying peroxide, prevents the formation of free radical and to the invasion and attack of unsaturated fatty acid.
Vitamin E can directly stimulate the B cell, makes spleen antibody-producting cell number increase; The T cell maturation be can promote, T cell and lymphocytic immunoreation stimulated.
Vitamin E can keep the complete of erythrocyte, promotes the biosynthesis of erythrocyte.This synthetic be to participate in the DNA biosynthesis by regulating the structure that pyrimidine base enters nucleic acid, particularly evident in producing erythrocytic bone marrow.
Vitamin E is the important factor that promotes Cellular respiration, particularly protects lung tissue to exempt from injury.
Vitamin E can make the intravital vitamin A content of people increase, and also can prevent the vitamin C oxidation.
The critical function of vitamin E is a slow down aging, resists tumor, prevents cardiovascular disease.
So vitamin A, C, E all participate in making in the cell activity of upgrading and rejecting the bad element.
Photosynthetic bacteria is a big class aquatic microorganisms, adheres to the beneficial microbe of three sections separately, i.e. Rhodospirillaceae, Chloracea, Chromatiaceae.It acts on following points:
(1) directly nutrition provides the animal growth desired material.
(2) improve condition of water quality, the protection water body environment.
(3) activated immune system improves animal disease resistance ability.
(4) suppress growth of pathogenic bacteria, passivation virus pathogenecity.
Photosynthetic bacteria group (good gas and anaerobies) is as photosynthetic bacteria and blue bath class.Photosynthetic bacteria group is separated by autotrophic microbe, has the specific function of turning harm into good, harmful substance can be transformed into innocuous substance, and be substrate with secretions, Organic substance, harmful gas (hydrogen sulfide etc.) and the carbon dioxide of plant, ammonia etc., synthetic saccharide, amino acids, vitamins, the plain chemical compound of ammonia and the physiology property controlled material etc. are rich soil and the key component that promotes animal and plant growth.The metabolite of photosynthetic bacteria group can directly be absorbed by plant, also can become other beneficial microorganism nutrient substance.Therefore, along with the propagation of photosynthetic bacteria group, the also corresponding propagation of other beneficial microbe.
Lactobacillus be applicating history the earliest, use the probiotic bacteria class of most species, main kind has bacillus acidophilus, lactobacillus, bacillus bifidus, streptococcus faecalis, urine streptococcus etc.Have following function:
(1) the main member in the animal intestinal profitable strain;
(2) produce organic acid antagonism pathogenetic bacteria;
(3) synthetic vitamin B group;
(4) generation of inhibition ammonia, amine substance helps the animal health growth;
(5) suppress breeding field planting and the absorption of harmful bacterium in intestinal such as escherichia coli, Salmonella;
(6) activated immune system, enhancing immunity;
Its material such as saccharide of producing based on picked-up photosynthetic bacteria, yeast of lactobacillus (anaerobies), making lactic acid.Lactic acid has very strong sterilizing ability, can effectively suppress the harmful microbe activity, and organic rapid corrupt the decomposition.Lactobacillus can make under the normality not labile lignin and cellulose etc. become to decompose easily, and eliminate all drawbacks that undecomposed Organic substance produces, the important function of performance shock brigade on organic matter fermentation decomposes, the organic substance that it will not become thoroughly decomposed changes into the effective nutrient of animals and plants.Another important function of lactobacillus can suppress the pathogenic bacterium propagation that continuous cropping obstacle produces exactly.Generally speaking, if pathogenic bacterium increase, plant will be weak, and harmful nematode also can sharply increase.Lactobacillus has suppressed the activity of pathogenic bacterium, and harmful nematode also fades away.
The strain that yeast is used as bio-additive mainly contains beer yeast, oil yeast etc.Its effect is summarized as follows:
(1) rich in proteins and vitamin B group can be done direct nutrition, and the animal multiple nutritional components is provided;
(2) increase gastrointestinal absorbing to nutrient substance
(3) improve the interior flora structure of gastrointestinal, promote the growth and the breeding of probiotics;
(4) repel the absorption field planting of pathogen, prevent the absorption of toxin and refuse on the intestinal mucosa surface;
(5) immunity of enhancing body and resistance against diseases.
Yeast flora (good gas) it utilize aminoacid, saccharide and other organic substance to produce fermenting power, produces to promote fissional activation material.Yeast provides important subsistence support for the production that the effective microbe (as lactobacillus, actinomycetes) that promotes other is bred needed substrate (food) in EM group army.In addition, the single cell protein of yeast production is the indispensable effective nutrient of animal.
Actinomycetes are intermediaries of cell and mycete.It obtains aminoacid, ammonia element etc. as substrate from photosynthetic bacteria, produce various antibiotics, can directly suppress pathogen.It obtains harmful mycete and the needed substrate of bacterial multiplication in advance, thereby suppresses their propagation, and creates the living environment of other beneficial microbe propagation.The mixed bacterial that actinomycetes and photosynthetic bacteria are formed, its bacteriostasis is multiplied than single actinomycetes.In addition, the easy passive plant absorbing of material of being decomposed by actinomycetes, thus strengthen repellence and the immunity of animals and plants to various diseases.
Be subjected to the disease of bacteriovirus infection a lot, as enteritis, tuberculosis, hepatitis B, encephalitis, the plague, SARS, AIDS etc., infection mechanism is similar, and treatment all has big difference, and special-purpose vaccine and special-purpose medicaments are respectively arranged.So far, there is not the medicine of broad spectrum activity that various disease conditions is all had better therapeutic effect.
Human diseases is mostly by due to noxious bacteria, the viral infection, and organic disease also mostly causes the imbalance of DNA command system, RNA combat system confusion, cytometaplasia by the gene origin.If these systems are normal, then the noxious bacteria zero-clearance can bore, and virus is contact pin nowhere, and disease will be left away, and health will perpetuity.
But in the real life, the noxious bacteria of occurring in nature, various panoramic viruses are being attacked the mankind all the time, cause to human health to have a strong impact on.Their seek the environment of breeding growth, and they enlarge the manor, launch a offensive the source of disease that Here it is to human body normal gene cell constantly expanding military capabilites.
Because the gene cell difference causes the human body cell difference.Antibacterial is also different with the point of attack of virus, and the kinds of Diseases that cause are also different.Such as: SARS is exactly by due to the coronavirus attack respiratory system; Hepatitis B is exactly that hepatitis B virus is attacked due to the hepatocyte.The kind of noxious bacteria is a lot, along with the evolution of biology, can produce various hybrid viruses, also can produce the hazardness virus bigger than atypical pneumonia.Studies show which kind of antibacterial, virus all have the point of attack that causes the people fatal position, destroy the genic system of human body exactly, DNA, RNA and cell system.Be exactly simply to scald, also destroyed these systems, just cause injury, human beings'health is not ensured.
Also do not have a kind of medicine at present in the world, put the axe in the helve from the root of disease.Existing medicine all is can play medical effect at a kind of disease, the single medicine that vaccine is also developed at certain viral disease.Just headache is cured head, the painful doctor of foot foot, and its curative effect does not have broad spectrum activity.By today, still do not match the various medicines that enhancing reparation gene impels cell division, regeneration effect that have according to aforementioned reason, carry out the medicine health product that the biological engineering assembly is made.
Summary of the invention
Goal of the invention
The object of the invention is for providing a kind of health medicine compositions.
Another object of the present invention is the preparation method that aforementioned pharmaceutical compositions is provided.
A further object of the present invention is for providing the purposes of aforementioned pharmaceutical compositions, especially the application aspect preparation prophylactic treatment SARS medicine.
Brief description
The invention provides a kind of health medicine composition and method of making the same, belong to the health care field of medicaments.Carry out biofermentation by photosynthetic bacteria group, Chinese herbal medicine serosity, mineral solution, Mel, the thread flora of same then lactobacillus, yeast flora, Gram positive actinomycetes group, fermentation system forms five microbiologic populations of family, obtain starter, then this starter and nucleic acid, vitamin, SOD, aminoacid are carried out biological emulsifying, obtain the present composition.The present composition especially has the good preventing therapeutic effect to SARS having a wide range of applications aspect preparation treatment broad spectrum of bacteria disease, wide spectrum viral disease, gene impairing, the impaired disease medicament of cell.
Describe in detail
Health medicine compositions of the present invention, fermenting by the thread flora that utilizes photosynthetic bacteria group, Chinese herbal medicine serosity, mineral solution, Mel, lactobacillus, yeast flora, gram defence line flora, fermentation system obtains starter, again starter and nucleic acid, vitamin mixture, SOD, aminoacid is carried out emulsifying and makes.
If the present composition is exclusively used in the health therapy of respiratory tract system disease, above-mentioned starter also should add the xylitol of the 3-10% of Mel weight in preparation process.
Health medicine preparation of compositions method of the present invention may further comprise the steps:
(1) preparation of Chinese herbal medicine serosity: after propolis 3-10 weight portion, Radix Astragali 5-11 weight portion, Ganoderma 1-3 parts by weight of crushed, add the boiling of water 40-80 weight portion and decoct to the 50-65% of slurry volume for the adding water volume, standby;
(2) preparation of mineral solution: soluble Zn 25-45 weight portion, solubility selenium 10-35 weight portion, soluble magnesium 15-25 weight portion and water 50 weight portions are evenly stirred, standby;
(3) fermentation: thread flora fermenting twice or one time fermentation with photosynthetic bacteria group, Chinese herbal medicine serosity, mineral solution, Mel/Mel and xylitol, water, lactobacillus, yeast flora, Gram positive actinomycetes group, fermentation system obtain starter after the filtration;
(4) emulsifying: starter 60-110 weight portion, nucleic acid 5-10 weight portion, vitamin mixture 3-10 weight portion and SOD0.05-0.5 weight portion are carried out mixing and emulsifying in the biological cell mulser, promptly.
Solubility selenium is sodium selenate, sodium selenite or seleno-amino acids (selenomethionine, selenocystine) in the described step of above-mentioned preparation method (2); The selenic addition of solubility is controlled at 1.5mg/kg, promptly in the 1kg product, adds the solubility selenium of about 1.5mg;
Soluble Zn is zinc sulfate, zinc acetate, zinc citrate, zinc glycyrrhetate, zinc gluconate, various amino-acid zinc or soluble Zn goods;
Soluble magnesium is magnesium gluconate, magnesium oxide or Fructus Hordei Germinatus; When using Fructus Hordei Germinatus, consumption is as the criterion with content of magnesium.
The vitamin mixture is the vitamin combination of following weight portion in the described step of above-mentioned preparation method (4):
Vitamin A 0.02-0.8
Vitamin C 2-5
Vitamin E 0.2-5.
The fermenting twice process is in the described step of above-mentioned preparation method (3):
(1) Chinese herbal medicine serosity 10-30 weight portion, mineral solution 0.12-0.15 weight portion, Mel 3-10 weight portion/Mel 3-10 weight portion and xylitol 0.09-1 weight portion, photosynthetic bacteria group 1-3 weight portion, water 30-70 weight portion are mixed, ferment for the first time; First fermentation is to carry out under the anaerobism enclosed environment, and fermentation temperature is controlled at 25-50 ℃, when fermentation body PH is 4.6-5.5, and first fermentation ends;
(2) after the first fermentation ends, the flora mixture to fermentation body adding fermentation body weight 1/6.5～1/14.5 carries out ferment in second time; Ferment in second time under anaerobic, temperature is controlled to be 25-40 ℃, when fermentation body PH is 4.6-5.5, stops fermentation, obtains starter after filtration; Flora mixture weight part is composed as follows:
Yeast flora 1-2.5
Gram positive actinomycetes group 1.5-3
The thread flora 1-2.5 of fermentation system
Lactobacillus 1.5-3.
The one time fermentation process is in the described step of above-mentioned preparation method (3): yeast flora, the Gram positive actinomycetes group of aforementioned quantities, thread flora, lactobacillus, photosynthetic bacteria group, the water of the system of fermenting are mixed under the anaerobism enclosed environment with Chinese herbal medicine serosity, mineral solution, Mel/Mel and xylitol, at 25-50 ℃ of bottom fermentation, when fermentation body PH is 4.6-5.5, stop fermentation, filter, obtain starter.
Filtration in the described step of above-mentioned preparation method (3) can be to use the mode of Chinese medicine filter, filter cloth or filter screen, and fineness is controlled to be the 180-250 order.
Above-mentioned photosynthetic bacteria group, Gram positive actinomycetes group, fermentation are that thread flora is provided by the Bai Li of Shenzhen Science and Technology Ltd.; Lactobacillus, yeast flora are provided by Shanghai institute of microbiology.Simultaneously, described flora all can be bought in BeiJing ZhongKe institute of microbiology of institute.Its specific descriptions all there is detailed description in following publication:
| Publication | Publishing house | Publication time |
| Food Microbiology (second edition) | The China Agricultyre University Press | ????2002-01-01 |
| General microbiology // national AGRICULTURAL UNIVERSITIES AND COLLEGES teaching material | The China Agricultyre University Press | ????2002-06-01 |
| Fermentation microbiology // national AGRICULTURAL UNIVERSITIES AND COLLEGES teaching material | The China Agricultyre University Press | ????1999-08-01 |
| Food Microbiology // institution of higher education's light industry specialty teaching material on probation | China Light Industry Press | ????2002-01-01 |
| Newly organized Food Microbiology | China Light Industry Press | ????1998-09-01 |
| Industrial microbiology // institution of higher education's teaching material | Chemical Industry Press | ????2001-06-01 |
Vitamin and SOD all are available commercially.As the SOD that the huge rich technology development center in Beijing provides, specific activity is 3000-6000u/mg, dried frozen aquatic products (white powder).
The storage of fermentation back intermediate products among the present invention, fermentation back intermediate products carry out the process of mixing and emulsifying, the storage of end product, all should carry out under 0-5 ℃ temperature.
Weight portion mentioned above can be mg, g, kg, jin, conventional units such as two.
The present composition especially has the good preventing therapeutic effect to SARS having a wide range of applications aspect preparation treatment broad spectrum of bacteria disease, wide spectrum viral disease, gene impairing, the impaired disease medicament of cell.
Product instructions of taking of the present invention:
Oral: the lighter three times/day, 50ml/ time; Weight person 50-100ml/ time; It is harmless that dangerous patient needs only comfortable many clothes; After the getting up early, before sleep evening, on an empty stomach for well.Rescue the each 100-150ml of poisoner.
Obey together with food: consumption 20-50ml, admix food (below 40 ℃), can obtain effect same.
Obey together with medicine: consumption 50-100ml, better effects if can make the drug effect multiplication, but can not be with the antibiotic medicine with using.
Product of the present invention 30 days was a course of treatment.Be used for detoxifcation, but acute poisoning person 1-2 days rehabilitation, and severe patient generally got final product rehabilitation in 3-5 days.
Take this product, taboo is drunk, and takes the antibiotic medicine.
Product of the present invention external application under any condition is used and is all produced effect, and clothes are inhaled in wound, dermatosis, sexually transmitted disease (STD) vaporization, and effect is better.
Beneficial effect
Product of the present invention has good medical health effect to broad spectrum of bacteria disease, wide spectrum viral disease, gene impairing, the impaired disease of cell, especially SARS is had the good preventing therapeutic effect; Can eliminate too much free radical in the human body; the protection internal organs preserve from; slow down aging; strengthen and improve immunity the medical effect that is showing is very much arranged; organ disease particularly; as tumor, pneumonopathy, various ulcer, various hepatopathy, pancreatic diseases, gi system disease, the various diseases that antibacterial and virus cause has tangible clinical treatment effect.
The adding of vitamin and mineral has increased medical effect of the present invention and broad spectrum activity.Particularly activate the activity of enzyme system in the body, participate in intensive aspect in the composition of various metalloenzyme, exchange the DNA building-up process around the ganglion cell, the growth of pair cell, division, differentiation play an important role.Particularly synthetic and excretory effect is the most apparent to hormonal system, insulin and testosterone; The tumor cell that detoxifies, protects the liver, kills is improved the oxygen delivery capacity of blood, quicken blood circulation, improve the insulin level of cell, the ability of blood sugar regulation has apparent positive effect.
Product maximum function of the present invention is the human body static organ, and it can keep the normal operation of human body, as the hyperpietic is had hypotensive effect; The hypotensive there is boosting; The high people's blood glucose of blood glucose is reduced; The low people's blood glucose of blood glucose is improved.
Can protect human body beneficial's thing, get rid of human body harmful's thing.So product of the present invention has tangible medical effect to following disease:
To serious viral dermatosis (psoriasis, hemorrhoid, lupus erythematosus, mosquito bite, scabies disease etc.), various sexually transmitted disease (STD), tangible medical effect is arranged;
Mus medicine, pesticide, cockroach killing chemicals are poisoned, and quick rescued effect is arranged;
Eriocheir sinensis poisoning, mushroom poisoning there are quick treatment, recovery from illness effect;
Symptom to the cancer patient chemotherapeutic period has tangible elimination effect;
Cholelithiasis, calculus of urethra there are tangible fossil, remove masonry usefulness;
To specific medical effects of gi system disease such as gastric ulcer, enteritis, chronic enteritiss;
Diabetes there is tangible medical effect;
Burn, scald, cold injury there is tangible rapid healing effect;
Defying age, health invigorating, preventing cold all there is special effect.
The specific embodiment
Embodiment 1
Propolis 3kg, Radix Astragali 5gk, Ganoderma 2kg are pulverized, add 40kg water, decoct, stop to decoct, get the Chinese herbal medicine serosity to 25kg, standby.
Zinc gluconate 45g, sodium selenate 30g, magnesium gluconate 25g are added 50g water, mix, get mineral solution, standby.
Chinese herbal medicine serosity 25kg, mineral solution 0.15kg are mixed, add Mel 5kg, photosynthetic bacteria group (Bai Li of Shenzhen Science and Technology Ltd. provides) 3kg, water 65.5kg, under 35 ℃, ferment, pH value is 5.5 after 96 hours time, stops fermentation and obtains the one time fermentation body;
Add 11kg flora mixture, yeast flora (20-50 hundred million/g wherein, Shanghai institute of microbiology provides) 2.5kg, Gram positive actinomycetes group (7.5-20 hundred million/g, Shenzhen Bai Li Science and Technology Ltd. provides) the thread flora (15-40 hundred million/g of 3kg, fermentation system, Shenzhen Bai Li Science and Technology Ltd. provides) 2.5kg, lactobacillus (15-30 hundred million/g, Shanghai institute of microbiology provides) 3kg, under 35 ℃, continue to ferment to PH be 5 o'clock, stop fermentation, the Chinese medicine filter filters, and fineness is controlled at 180 orders, obtains starter, seal up for safekeeping for 0 ℃, stand-by.
Starter 109.65kg, nucleic acid 5kg, vitamin mixture 10kg, SOD concentrated solution 0.5kg are mixed, in the high shear separator cell, carry out biological emulsifying, obtain health composition 125kg of the present invention; Wherein the vitamin mixture contains vitamin A 0.77kg, vitamin C 4.62kg, vitamin E 4.61kg; The ambient temperature of mixing, emulsion process is 0 ℃.
Embodiment 2
Propolis 5kg, Radix Astragali 11kg, Ganoderma 1kg are pulverized, add 50kg water, decoct, stop to decoct, get the Chinese herbal medicine serosity to 25kg, standby.
Zinc glycyrrhetate 25g, sodium selenite 35g, magnesium gluconate 15g are added 50g water, mix, get mineral solution, standby.
Chinese herbal medicine serosity 10kg, mineral solution 0.125kg are mixed, add Mel 3kg, photosynthetic bacteria group 1kg, water 40kg, under 25 ℃, ferment, to pH value be 5.0 o'clock, stop fermentation, obtain the one time fermentation body;
Add 8kg flora mixture, the thread flora 1.0kg, the lactobacillus 3kg that wherein add yeast flora 2.5kg, Gram positive actinomycetes group 1.5kg, fermentation system, under 35 ℃, continue to ferment to PH be 5 o'clock, stop fermentation, the use filter cloth filters, and fineness is controlled to be 200 orders, obtains starter, seal up for safekeeping for 0 ℃, stand-by.
Starter 62.125kg, nucleic acid 10kg, vitamin mixture 3kg, SOD concentrated solution 0.1kg are mixed, in the high shear separator cell, carry out biological emulsifying, obtain health composition 73kg of the present invention; Wherein the vitamin mixture contains vitamin A 0.02kg, Catergen .61kg, vitamin E 0.37kg; The ambient temperature of mixing, emulsion process is 1 ℃.
Embodiment 3
Propolis 10kg, Radix Astragali 6kg, Ganoderma 3kg are pulverized, add 80kg water, decoct, stop to decoct, get the Chinese herbal medicine serosity to 52kg, standby.
Zinc citrate 40g, selenomethionine 10g, magnesium oxide 20g are added 50g water, mix, get mineral solution, standby.
Chinese herbal medicine serosity 30kg, mineral solution 0.12kg are mixed, add Mel 9.5kg, xylitol 150g, photosynthetic bacteria group 2kg, water 50kg, under 40 ℃, ferment, to pH value be 4.6 o'clock, stop fermentation, obtain the one time fermentation body;
Add 6.5kg flora mixture, the thread flora 1.0kg, the lactobacillus 1.5kg that wherein add yeast flora 1.0kg, Gram positive actinomycetes group 3kg, fermentation system, under 35 ℃, continue to ferment to PH be 5 o'clock, stop fermentation, strainer filtering, fineness are controlled at 250 orders, obtain starter, seal up for safekeeping for 0 ℃, stand-by.
Starter 98.27kg, nucleic acid 7kg, vitamin mixture 5kg, SOD concentrated solution 0.05kg are mixed, in the high shear separator cell, carry out biological emulsifying, obtain health composition 110kg of the present invention; Wherein the vitamin mixture contains vitamin A 0.07kg, vitamin C 3.95kg, vitamin E 0.98kg; The ambient temperature of mixing, emulsion process is 3 ℃.
Embodiment 4
Propolis 7.5kg, Radix Astragali 9kg, Ganoderma 1.5kg are pulverized, add 70kg water, decoct, stop to decoct, get the Chinese herbal medicine serosity to 42kg, standby.
Zinc acetate 30g, selenocystine 20g, Fructus Hordei Germinatus 22g are added 50g water, mix, get mineral solution, standby.
Chinese herbal medicine serosity 15kg, mineral solution 0.122kg are mixed, the thread flora 2kg, the lactobacillus 2kg that add Mel 7kg, xylitol 500g, photosynthetic bacteria group 1.5kg, water 35kg, yeast flora 2kg, Gram positive actinomycetes group 2kg, fermentation system, 50 ℃ of bottom fermentations to PH be 5, stop fermentation, the Chinese medicine filter filters, and fineness is controlled at 200 orders, obtains starter, seal up for safekeeping for 0 ℃, stand-by.
Starter 67.1kg, nucleic acid 9kg, vitamin mixture 7kg, SOD concentrated solution 0.3kg are mixed, in the high shear separator cell, carry out biological emulsifying, obtain health composition 83kg of the present invention; Wherein the vitamin mixture contains vitamin A 0.29kg, vitamin C 4.32kg, vitamin E2 .39kg; The ambient temperature of mixing, emulsion process is 5 ℃.
Experimental example 1
The dispelling toxicity, detoxicating effect:
5. 2002.5.1 takes cockroach killer 3g to kitten, and after 5 minutes, cat begins vomiting, after 10 minutes, just rare, astasia falls down gradually, pours into embodiment 1 product 50ml immediately, after 20 minutes, stand gradually, pour into again behind the 25ml and oneself to walk about in 10 minutes, can take food after 2 hours.
5. woman, 45 years old, the bright Semen Ginkgo 750g after 2001.10.15 takes microwave and bakes, sleeping aftersensation is felt sick, vomiting, dizziness, eyes are fuzzy, and are weak, can not stand, take embodiment 1 product 50ml at once, feel sick after 10 minutes and eliminate, go up toilet voluntarily after 20 minutes, recover normal after 30 minutes.
5. 2002.6.5,4 people are the male, eat Eriocheir sinensis and poison, and tell, let out more than, serious, take embodiment 1 product 100ml immediately, after 20 minutes, the equal emesis of 4 people, antidiarrheal.
Experimental example 2
Treatment to hepatitis B:
Hepatitis B patient 10 people do not cure, for many years through taking embodiment 1 product 2 months, transference cure.
Experimental example 3
To treating for skin disease:
Serious viral skin patient 10 people in the whole body, medical history 3-10 does not wait, oral, external application embodiment 1 product, symptom disappears substantially after 3 months.
Experimental example 4
Treatment to cholelithiasis, renal calculus, calculus of urethra:
Cholelithiasis patient 5 people, renal calculus patient 3 people, calculus of urethra patient 8 people, all serious symptom is had an attack of one's old illness for 1 week-do not wait January, also have an attack of one's old illness during improper diet, quote 1 product half a year-1 year of embodiment, the cycle stretch-out of having an attack of one's old illness, symptom is slowed down, and B ultrasonic shows that calculus obviously disappears.
Experimental example 5
Treatment to periodontitis, stomatitis, oral ulcer:
Patients with periodontitis 18 people, stomatitis patient 5 people, frequent oral ulcer patient 22 people take embodiment 1 product when having an attack of one's old illness, pain relieving in 2-3 hour, and disease is eliminated after 8-12 hour.
Experimental example 6
Treatment to digestive system disease such as gastric ulcer, chronic enteritiss:
5. patients having chronic intestinal inflammation 15 people, medical history 3-30 does not wait, morbidity at any time, the time is indefinite, adheres to taking embodiment 1 product 3 months, and sx continued to take all rehabilitations 3-6 month.
5. gastric ulcer patient 4 people, medical history 3-6 does not wait, and takes embodiment 1 product before the operation 2 months, reaches to return to one's perfect health.
Experimental example 7
To treatment of diabetes:
Diabetics 10 people, ill more than 10 years, syndrome has appearred, and hands, human hair combing waste life are festered, and take embodiment 1 product after 3 months-6 months, and blood glucose reduces to 6.5, and glucose in urine does not have (+), the recovery from illness of festering after 8 months.
Experimental example 8
To burn, scald, frosted treatment:
5. fire victim 3 people, scald patient 5 people are the women, spray embodiment 1 product after the wound immediately, pain relieving at that time, the back recovery from illness of 1 week.
5. cold injury patient 1 people, the women, the trick cold injury is red and swollenly also festered, and behind spraying embodiment 1 product 10 days, transference cure, no scar.
Experimental example 9
Treatment research to SARS:
Experiment in vitro shows that the SARS virus that product of the present invention is cultivated for chick embryo method is inhibited.The coronavirus genome is RNA, and by respiratory tract, mucosa or contact, virus mediates the glycoprotein receptor that is adsorbed in sensitive cells film or cell membrane through receptor, merges or melts in the film synthetic cell by film and swallow.The coronavirus geneome RNA enters the permissive cell kytoplasm, at first with himself geneome RNA as mRNA as early stage translation, required RNA polymerase is duplicated in generation, RNA polymerase is a template with viral genome+ssRNA more then, transcribe the generation strand RNA, with it is that template is transcribed the generation virus mRNA, forms progeny virus through translation and translation post-treatment packing then, and discharges in the mode of sprouting.The pathophysiological change of clinical symptoms mainly is that the polarity cytocidal infection takes place target cell, and is further development of the multiple organ failure, MOF.After SONGGUOJU polysaccharide of the present invention or its compositions enter human body, be adsorbed in the glycoprotein receptor of sensitive cells film or cell membrane, suppress the synthetic of virion nucleic acid, simultaneously, product of the present invention has good bactericidal antiphlogistic effect and significant immunity, the complication and the superinfection that can prevent and effectively control SARS to cause, the treatment level that helps treating SARS reduces the acute death rate of severe acute respiratory syndrome simultaneously.
Claims (9)
1, a kind of health medicine compositions, fermenting by the thread flora that utilizes photosynthetic bacteria group, Chinese herbal medicine serosity, mineral solution, Mel/Mel and xylitol, lactobacillus, yeast flora, gram defence line flora, fermentation system obtains starter, again starter and nucleic acid, vitamin mixture, SOD, aminoacid is carried out emulsifying and makes.
2, the described health medicine preparation of compositions of claim 1 method comprises:
(1) preparation of Chinese herbal medicine serosity: after propolis 3-10 weight portion, Radix Astragali 5-11 weight portion, Ganoderma 1-3 parts by weight of crushed, add the boiling of water 40-80 weight portion and decoct to the 50-65% of slurry volume for the adding water volume, standby;
(2) preparation of mineral solution: soluble Zn 25-45 weight portion, solubility selenium 10-35 weight portion, soluble magnesium 15-25 weight portion and water 50 weight portions are evenly stirred, standby;
(3) fermentation: thread flora fermenting twice or one time fermentation with photosynthetic bacteria group, Chinese herbal medicine serosity, mineral solution, Mel/Mel and xylitol, water, lactobacillus, yeast flora, Gram positive actinomycetes group, fermentation system obtain starter after the filtration;
(4) emulsifying: starter 60-110 weight portion, nucleic acid 5-10 weight portion, vitamin mixture 3-10 weight portion and SOD 0.05-0.5 weight portion are carried out mixing and emulsifying in the biological cell mulser, promptly.
3, preparation method according to claim 2 is characterized in that solubility selenium is sodium selenate, sodium selenite or seleno-amino acids in the described step (2); Soluble Zn is zinc sulfate, zinc acetate, zinc citrate, zinc glycyrrhetate, zinc gluconate, various amino-acid zinc or soluble Zn goods; Soluble magnesium is magnesium gluconate, magnesium oxide or Fructus Hordei Germinatus.
4, preparation method according to claim 3 is characterized in that the selenic addition of described solubility is controlled at 1.5mg/kg.
5,, it is characterized in that the vitamin mixture is the vitamin combination of following weight portion in the described step (4) according to the described preparation method of claim 2-4:
Vitamin A 0.02-0.8
Vitamin C 2-5
Vitamin E 0.2-5.
6,, it is characterized in that the fermenting twice process is in the described step (3) according to the described preparation method of claim 2-5:
(1) Chinese herbal medicine serosity 10-30 weight portion, mineral solution 0.12-0.15 weight portion, Mel 3-10 weight portion/Mel 3-10 weight portion and xylitol 0.09-1 weight portion, photosynthetic bacteria group 1-3 weight portion, water 30-70 weight portion are mixed, ferment for the first time; First fermentation is to carry out under the anaerobism enclosed environment, and fermentation temperature is controlled at 25-50 ℃, when fermentation body PH is 4.6-5.5, and first fermentation ends;
(2) after the first fermentation ends, the flora mixture to fermentation body adding fermentation body weight 1/6.5～1/14.5 carries out ferment in second time; Ferment in second time under anaerobic, temperature is controlled to be 25-40 ℃, when fermentation body PH is 4.6-5.5, stops fermentation, obtains starter after filtration; Flora mixture weight part is composed as follows:
Yeast flora 1-2.5
Gram positive actinomycetes group 1.5-3
The thread flora 1-2.5 of fermentation system
Lactobacillus 1.5-3.
7, according to the described preparation method of claim 2-5, it is characterized in that the one time fermentation process is in the described step (3): yeast flora, the Gram positive actinomycetes group of the described amount of claim 5, thread flora, lactobacillus, photosynthetic bacteria group, the water of the system of fermenting are mixed under the anaerobism enclosed environment with Chinese herbal medicine serosity, mineral solution, Mel/Mel and xylitol, at 25-50 ℃ of bottom fermentation, when fermentation body PH is 4.6-5.5, stop fermentation, filter, obtain starter.
8, according to the described preparation method of claim 2-7, it is characterized in that being filtered into the mode of using Chinese medicine filter, filter cloth or filter screen in the described step (3), fineness is controlled to be the 180-250 order.
9, the application of the described compositions of claim 1 aspect preparation treatment broad spectrum of bacteria disease, wide spectrum viral disease, SARS, gene impairing, the impaired disease medicament of cell.
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN100374137C (en) * | 2006-10-10 | 2008-03-12 | 王宗林 | Beautifying and spot eliminating health care product and its prepn process |
| CN101606952B (en) * | 2008-06-17 | 2012-09-19 | 上海交通大学医学院附属第三人民医院 | Application of bifidobacterium lactis in preventing medicine for urinary system calculus |
| CN103432387A (en) * | 2013-08-20 | 2013-12-11 | 冯子龙 | Chinese herbal medicine oral liquid for treating diabetes and production technology thereof |
| CN103637182A (en) * | 2013-11-01 | 2014-03-19 | 胡安然 | Special meal for low-immunity patient |
| CN105796704A (en) * | 2016-05-10 | 2016-07-27 | 南京明宽信息咨询中心 | Selenium-rich health product as well as preparation method and application thereof |
| CN106509863A (en) * | 2016-01-22 | 2017-03-22 | 山东源密码生物科技有限责任公司 | Male specific functional health-care oral liquid yang benefiting micro-organisms and preparation method thereof |
| CN107927267A (en) * | 2017-12-15 | 2018-04-20 | 哈尔滨商业大学 | A kind of honey ginger health protection tea and production method |
| CN108159385A (en) * | 2018-03-06 | 2018-06-15 | 黄振忠 | A kind of drug for treating frostbite |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1176790A (en) * | 1996-09-13 | 1998-03-25 | 盖军 | Prepn. contg. effedive micorbial population |
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- 2003-10-10 CN CNB2003101001200A patent/CN1302785C/en not_active Expired - Fee Related
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100374137C (en) * | 2006-10-10 | 2008-03-12 | 王宗林 | Beautifying and spot eliminating health care product and its prepn process |
| CN101606952B (en) * | 2008-06-17 | 2012-09-19 | 上海交通大学医学院附属第三人民医院 | Application of bifidobacterium lactis in preventing medicine for urinary system calculus |
| CN103432387A (en) * | 2013-08-20 | 2013-12-11 | 冯子龙 | Chinese herbal medicine oral liquid for treating diabetes and production technology thereof |
| CN103432387B (en) * | 2013-08-20 | 2016-09-28 | 冯子龙 | The Chinese herbal medicament oral liquid for the treatment of diabetes and production technology thereof |
| CN103637182A (en) * | 2013-11-01 | 2014-03-19 | 胡安然 | Special meal for low-immunity patient |
| CN106509863A (en) * | 2016-01-22 | 2017-03-22 | 山东源密码生物科技有限责任公司 | Male specific functional health-care oral liquid yang benefiting micro-organisms and preparation method thereof |
| CN105796704A (en) * | 2016-05-10 | 2016-07-27 | 南京明宽信息咨询中心 | Selenium-rich health product as well as preparation method and application thereof |
| CN107927267A (en) * | 2017-12-15 | 2018-04-20 | 哈尔滨商业大学 | A kind of honey ginger health protection tea and production method |
| CN107927267B (en) * | 2017-12-15 | 2020-11-06 | 哈尔滨商业大学 | Honey and ginger health-care tea and preparation method thereof |
| CN108159385A (en) * | 2018-03-06 | 2018-06-15 | 黄振忠 | A kind of drug for treating frostbite |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1302785C (en) | 2007-03-07 |
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