CN1493507A - Packaging method of hygroscopic medicine - Google Patents
Packaging method of hygroscopic medicine Download PDFInfo
- Publication number
- CN1493507A CN1493507A CNA021356661A CN02135666A CN1493507A CN 1493507 A CN1493507 A CN 1493507A CN A021356661 A CNA021356661 A CN A021356661A CN 02135666 A CN02135666 A CN 02135666A CN 1493507 A CN1493507 A CN 1493507A
- Authority
- CN
- China
- Prior art keywords
- medicine
- packing
- desiccant
- hygroscopic
- ground floor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Landscapes
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Packages (AREA)
- Drying Of Gases (AREA)
Abstract
A method for packing the hydroscopic medicine features that after the hydroscopic medicine is packed by a sealing layer, it along with the desiccant is packed by another sealing layer. It is possible to fill inertial gas in the space between said two sealing layers.
Description
Technical field
The present invention relates to a kind of packing method of hygroscopic medicine, be used for the medicine manufacture.
Background technology
There are some medicines that hygroscopic property is arranged; unsuitable long preservation; as: potassium clavulanate is a beta-lactamase inhibitor; share the antibacterial activity that can obviously increase the latter with penicillin medicine; and enlarge its antimicrobial spectrum; potassium clavulanate can suppress bacteriogenic beta-lactamase effectively, thereby the protection penicillin medicine exempts from destruction.Now the medicine that contains the potassium clavulanate component of listing mainly contains amoxicillin and clavulanate potassium sheet and other peroral dosage form product both at home and abroad, and this series of products clinical application range is wide, evident in efficacy, and share of market is higher.But the potassium clavulanate composition that contains in this medicine series has and draws moist strong attribute, medicine very easily absorbs water in air and divides oxidation, decomposes variable color in production, storage process, it is rotten to cause medicine just to lose efficacy in a short time, directly influences medicine at market sale and patient's drug safety.
At above-mentioned rough sledding, the measure of taking at present mainly is after packings such as product plastic-aluminum or aluminium aluminium and desiccant is adorned the box list marketing together, and desiccant is that medicine is created relatively dry environment of formation.Yet desiccant can lose the protective effect of application very soon because of absorbing moisture in the surrounding air, and its effect on moisture extraction is not satisfactory, and drug quality can't effectively be guaranteed in the subject word of regulation.As the amoxicillin and clavulanate potassium sheet, the manner of packing that adopts mostly is plastic-aluminum, aluminium aluminium packing greatly at present, keeping life is defined as 2 years, because very easily moisture absorption of potassium clavulanate composition in its prescription, under conventional production storage requirement, product absorbs behind the moisture can progressively oxidation, decomposition, cause the outward appearance of product and inherent quality generally in half a year with regard to the out of reach drug standard.
Summary of the invention
Technical matters to be solved by this invention is: a kind of packing method of hygroscopic medicine is provided, can makes the product design of medicine obtain in the subject word of regulation effectively, reliably guarantee.
The packing method of hygroscopic medicine of the present invention, at first medicine is carried out the ground floor sealed package after, carry out second layer sealed package with desiccant again.
Form double casing, the independent configuration of desiccant is arranged again, improved the storage environment of medicine greatly, make the product design of medicine in the subject word of regulation, can access effectively, reliably guarantee.
Charge into unreactable gas in the cavity between ground floor packing and overpack, as nitrogen, carbon dioxide etc., air displacement in its cavity is come out, further guarantee the seal isolation effect, stop of the influence of airborne moisture effectively to drug quality, the stability of medicine product is improved greatly, make drug quality meet the national drug quality loop before the deadline fully.
Desiccant is placed in the packaging bag, and production operation, use are convenient in safety and sanitation.
In actual applications, pack the medicine sealed package with ground floor, and then be packaged together in the overpack, charge into drying, unreactable gas that purity is high in the cavity between ground floor packing and overpack with desiccant bag, air displacement in its cavity is come out finally sealed.Packing material uses conventional drug packing material to get final product, and no specific (special) requirements is as plastic-aluminum, aluminium aluminium, mould aluminum composite membrane or the like; Desiccant also adopts pharmacy industry conventional drying agent to get final product, as silica gel etc.; The method for packing of packing is a routine techniques, also is not repeated.
The packing method simple possible of hygroscopic medicine of the present invention, be easy to the industrial implementation utilization, for hygroscopic medicine provides stable storage condition and environment, can obtain good sealing, drying effect, can make the product design of medicine in the subject word of regulation, obtain effectively, reliably guarantee.
Description of drawings
The structural representation of the packing medicine that Fig. 1, packing method of the present invention are implemented to form.
Among the figure: 1, packaged medicine 2, ground floor packing 3, overpack 4, one, two layer of packing cavity 5, desiccant bag.
The specific embodiment
The invention will be further described in conjunction with the foregoing description accompanying drawing.
The enforcement of the packing method of hygroscopic medicine of the present invention has formed packing medicine structure as shown in Figure 1.Hygroscopic medicine 1 is packaged in the ground floor packing 2, and ground floor is packed 2 outsourcings overpack 3 is housed, and is equipped with desiccant bag 5 in the cavity 4 that ground floor packing 2 and overpack are 3, and is filled with unreactable gas.
Packing method is: after medicine 1 is carried out the ground floor sealed package, carry out second layer sealed package with desiccant bag 5 again, charge into unreactable gas, finally sealed in the cavity 4 of 3 of ground floor packing 2 and overpacks.
Claims (3)
1, a kind of packing method of hygroscopic medicine after it is characterized in that medicine carried out the ground floor sealed package, is carried out second layer sealed package with desiccant again.
2, packing method according to claim 1 is characterized in that charging into unreactable gas in the cavity between ground floor packing and overpack.
3, packing method according to claim 1 and 2 is characterized in that desiccant is placed in the packaging bag.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA021356661A CN1493507A (en) | 2002-10-30 | 2002-10-30 | Packaging method of hygroscopic medicine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA021356661A CN1493507A (en) | 2002-10-30 | 2002-10-30 | Packaging method of hygroscopic medicine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1493507A true CN1493507A (en) | 2004-05-05 |
Family
ID=34231472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA021356661A Pending CN1493507A (en) | 2002-10-30 | 2002-10-30 | Packaging method of hygroscopic medicine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1493507A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102245482B (en) * | 2008-12-01 | 2012-09-26 | 千住金属工业株式会社 | Package for storing minute solder ball and method for storing minute solder ball |
| CN107108104A (en) * | 2015-01-09 | 2017-08-29 | 千住金属工业株式会社 | Soldered ball container and soldered ball preservation packaging body |
-
2002
- 2002-10-30 CN CNA021356661A patent/CN1493507A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102245482B (en) * | 2008-12-01 | 2012-09-26 | 千住金属工业株式会社 | Package for storing minute solder ball and method for storing minute solder ball |
| CN107108104A (en) * | 2015-01-09 | 2017-08-29 | 千住金属工业株式会社 | Soldered ball container and soldered ball preservation packaging body |
| CN107108104B (en) * | 2015-01-09 | 2018-09-04 | 千住金属工业株式会社 | Container, packaging body and the method for closing container |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP3197187U (en) | Medicine bottle with solid silica chip desiccant | |
| RU2448026C2 (en) | Package with pharmaceutical preparations | |
| US4753352A (en) | Impervious packaging in the form of a card having compartments and permitting gaseous exchange between the compartments | |
| AU643536B2 (en) | Package | |
| US6050400A (en) | Package | |
| WO2004080808A3 (en) | Films having a desiccant material incorporated therein and methods of use and manufacture | |
| CN2897869Y (en) | Packing bag | |
| US20210015776A1 (en) | Methods of stabilization of levothyroxine sodium tablets | |
| CN2603785Y (en) | Medicine wrapper | |
| CN1493507A (en) | Packaging method of hygroscopic medicine | |
| EP2836458B1 (en) | Oxygen-releasing inserts | |
| AU3837000A (en) | Packing container and packing method | |
| CN207141789U (en) | A kind of friable food product plastic packaging bag | |
| CN202828402U (en) | Sealing box | |
| CN103009747B (en) | A kind of dehumidifying moisture-proof package film and preparation method thereof | |
| CN203075205U (en) | Packaging combination of nicorandil preparation | |
| JP5132377B2 (en) | Method for preserving articles by double packaging | |
| CN205633649U (en) | High sealed pharmaceutical packaging case structure | |
| CN2559591Y (en) | Double-layer sealing dampproof bottle cover | |
| CN202637478U (en) | Lavipeditum effervescent tablet | |
| CN2612629Y (en) | safe moisture proof pesticide smoke packing | |
| CN2144506Y (en) | Nitroglycerin tablet packing bag | |
| CN207346384U (en) | Chinese medicine packing box | |
| CN206288451U (en) | A kind of convex-concave slot type combination sauce packaging | |
| CN201782949U (en) | Penicillin bottle package with combined cover |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |