CN1453019A - Chinese medicine for treating eye diseases of middle-aged and old people and its prepn - Google Patents
Chinese medicine for treating eye diseases of middle-aged and old people and its prepn Download PDFInfo
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Abstract
The present invention is one Chinese medicine for treating eye diseases of middle-aged and old people and its preparation. The medicine is prepared with Chinese medicinal materials rehmannia root, Chinese yam, ginseng, wolfberry fruit, dogwood, etc. It has the functions of nourishing liver and kidney, improving eyesight, clearing away heat, promoting diuresis, expelling wind, etc; and is used in treating cataract, optic atrophy, glaucoma and other eye diseases. It has the features of synergistic effects of its various medicinal components, fast acting, no toxic side effect, etc.
Description
One, technical field:
The present invention relates to Chinese medicine of a kind of person in middle and old age's of treatment ocular disease and preparation method thereof.Specifically describing is to be raw material with the Chinese herbal medicine, through a kind of glaucoma, high intraocular pressure of being used for the treatment of that the specific process Processing of Preparation forms, first mid-term cataract, pure compound Chinese medicinal preparation of diseases such as optic atrophy and preparation method thereof.
Two, background technology:
Cataract is meant lenticular opacity, the slow chronic ophthalmic of falling, gradually extremely losing one's sight of vision.Because of circular silvery white or tan cataracta finally occur among pupil god, the traditional Chinese medical science claims cataract.Cataract is a blind rate disease with high in the world always, has data to show that whole world blind person (vision is below 0.05) has the forty-two million people approximately, wherein because of about 1,700 ten thousand people of cataract blinding person.China has cataract patient 5,060,000 people at present approximately, wherein blind person 1,980,000 people.Cataract account for old people's vision invalid 60.19%.Cataract is divided initial phase cataract, immature phase cataract, complicated cataract, senile cataract, senile cataract is modal a kind of in the cataract, account for more than 50%, it also is the main cause that the old people loses one's sight, according to incompletely statistics, the sickness rate of 50-60 year person's senile cataract is 60%-70%, and the person 80% more than 70 years old.At present, mature cataract is based on operation (artificial intraocular lenses's art, cataractopiesis) treatment, but operative treatment also severe complications can occur sometimes, and is difficult to handle, and directly influences therapeutic effect.Therefore, seek the regeneration of effective ways prevention cataract, reaching therapeutic purposes is our research directions.
Three, summary of the invention:
The object of the present invention is to provide a kind of nourishing the liver and kidney that has, replenishing vital essence to improve eyesight, clearing away heat-damp and promoting diuresis, the effect of expelling wind and removing nebula, be used for the treatment of owing to both liver and kidney deficiency Chinese medicine of ophthalmic diseases such as cataract that asthenia of essence and blood etc. cause and optic atrophy, glaucoma and preparation method thereof.
For achieving the above object, the technical solution used in the present invention is:
A kind of Chinese medicine for the treatment of person in middle and old age's eye disease, its special character is: the medicament that the Chinese medicine of described treatment person in middle and old age eye disease is made by the raw material of following weight proportion: antelope's horn 1-3 part puncture vine 30-50 part scouring rush 20-40 part chrysanthemum 40-60 part plantain seed 20-40 part selfheal 20-40 part cassia seed 30-50 part ginseng 10-25 part Fructus Corni 20-40 part stem of noble dendrobium 30-50 part fruit of Chinese wolfberry 30-50 part seed of Chinese dodder 20-40 part fruit of glossy privet 20-40 part shell of seaear 40-60 part coptis 5-25 part pipewort 20-40 part akebi 20-40 part prepared rhizome of rehmannia 20-40 part Chinese yam 20-40 part rhizoma alismatis 5-25 part Poria cocos 20-40 part moutan bark 20-40 part glutinous rehmannia 20-40 part betel nut 20-40 part
The medicament that the Chinese medicine of above-mentioned treatment person in middle and old age ocular disease is made by following materials of weight proportions:
50 parts of 25 parts of Flos Chrysanthemis of 40 parts of Herba Equiseties Hiemalis of 1 portion of Fructus Tribuli of Cornu Saigae Tataricae
15 parts of 40 parts of Radix Ginsengs of 25 parts of Semen Cassiaes of 25 parts of Spica Prunellaes of Semen Plantaginis
25 parts of 40 parts of Semen Cuscutae of 40 parts of Fructus Lycii of 25 parts of Herba Dendrobiis of Fructus Corni
25 parts of 10 parts of Flos Eriocaulis of 50 portions of Rhizoma Coptidis of 25 parts of Concha Haliotidis of Fructus Ligustri Lucidi
10 parts of 25 portions of Rhizoma Alismatis of 25 portions of Rhizoma Dioscoreaes of 25 parts of Radix Rehmanniae Preparata of Caulis Akebiae
25 parts of 25 portions of Semen Arecaes of 25 portions of Radix Rehmanniae of 25 parts of Cortex Moutans of Poria
Above-mentioned medicament is the above a dosage form of any pharmaceutics.
Above-mentioned dosage form is tablet, capsule.
Above-mentioned dosage form is that the processing step of preparation method of tablet is as follows:
(1), Fructus Corni sprayed to mix thoroughly to steam with yellow wine form, standby;
(2), get that Fructus Tribuli, Herba Equiseti Hiemalis, Flos Chrysanthemi, Semen Plantaginis, Semen Cassiae, Fructus Corni, Herba Dendrobii are ground into 100-120 order fine powder, sieve, mixing;
(3), get Cornu Saigae Tataricae, Radix Ginseng and be ground into 120 order fine powders separately, again with above-mentioned steps (2) in 100-120 order fine powder mixing, standby;
(4), get ten five tastes such as all the other Fructus Lycii, decoct with water secondary, each two hours, collecting decoction filters, and being evaporated to temperature and being 80 ℃, relative density is the thick paste of 1.27-1.30, with above-mentioned steps (3) Chinese medicine powder mixing, right amount of auxiliary materials is pulverized, sieves, added to drying, mixing, granulate, drying, compacting is in flakes, sugar coating promptly can be made into tablet.
Above-mentioned dosage form is that the processing step of capsular preparation method is as follows:
(1), Fructus Corni sprayed to mix thoroughly to steam with yellow wine form, standby;
(2), get that Fructus Tribuli, Herba Equiseti Hiemalis, Flos Chrysanthemi, Semen Plantaginis, Semen Cassiae, Fructus Corni, Herba Dendrobii are ground into 100-120 order fine powder, sieve, mixing;
(3), get Cornu Saigae Tataricae, Radix Ginseng and be ground into 120 order fine powders separately, again with above-mentioned steps (2) in 100-120 order fine powder mixing, standby;
(4), get ten five tastes such as all the other Fructus Lycii, decoct with water secondary, each two hours, collecting decoction, filter, being evaporated to temperature and being 80 ℃, relative density is the thick paste of 1.27-1.30, with above-mentioned steps (3) Chinese medicine fine powder mixing, dry, pulverize, sieve, add right amount of auxiliary materials, mixing is granulated, drying, encapsulated getting final product.
The present invention is with respect to prior art, and its advantage is as follows:
The present invention has the compatibility science, monarch, minister, helps, makes medication collaborative, short treating period, and instant effect, clinical use has no side effect, and consolidates the rate height, is difficult for the compound Chinese medicinal preparation of recurrence.
The present invention adopts advanced Chinese medicine processing extraction equipment, extracts with the technology of science uniqueness, separates the active ingredient method, and compound making is convenient to oral pure Chinese medicinal tablet easy to carry.This medicine has embodied treating both the principal and secondary aspects of a disease from clinical efficacy, dialectically execute control clinical the medicine principle is arranged, given prominence to Chinese medicine in all kinds of kinds of nebulas of clinical ophthalmology field treatment, glaucoma, cataract from characteristic, need not implement operation, reach by oral administration and eliminate eye cataracta lesions position absorption clinical treatment purpose.
Pure Chinese medicinal preparation of the present invention is from technology theory, changed ancient Chinese medicine decoction method, its crucial production technology has adopted modern science Chinese medicine extraction principle, and utilization modern crafts extractive technique is according to the characteristic of prescription, take a part of crude drug in whole micronizing, the part extract drugs is separated the active ingredient technology, is convenient to control its quality standard detection, taking convenience thereby make, stable curative effect, the Chinese medicine preparation of the transportation that is easy to carry.
Four, specific embodiment:
According to the research of motherland's traditional medicine and modern medicine to the cataract cause of disease and pathology, theory with " the essence of five ZANG-organs and six FU-organs gas all on annotate " in order, adopt the microscopic diagnosis of modern medicine to control the means that combine, develop this pure compound Chinese medicinal preparation with the whole dialectical opinion of the traditional Chinese medical science.
Respectively the distinguish the flavor of property of medicine of medicine of prescription of the present invention is:
1, Cornu Saigae Tataricae: the angle that derives from the bovid sahilite.Nature and flavor: become, tremble with fear, return liver, heart channel, performance characteristics: this product is cold in nature, goes into Liver Channel liver heat removing suppressing the hyperactive liver, endogenous wind stopping relieving convulsion, for treating the liver wind tic key medicine, goes into heart channel clearing away heart-fire detoxification, kind heart channel intenseness of heat, the dry mad card of coma controlled.
2, Fructus Tribuli: the dry fruit that derives from zygophyllaceae plant Fructus Tribuli.Nature and flavor: bitter, hot, flat.Performance characteristics: suppressing the hyperactive liver is soothing the liver, dispelling pathogenic wind for improving eyesight, and dispelling wind for relieving itching is applied to wind heat conjunctival congestion cataracta.
3, Herba Equiseti Hiemalis: the dry aerial parts that derive from Equisetaceae plant Herba Equiseti Hiemalis.Nature and flavor: sweet, bitter flat.Return lung, Liver Channel.Performance characteristics: the wind heat of loosing, move back corneal nebula.Be applied to the wind heat conjunctival congestion, epiphora induced by wind, order is given birth to nebula.
4, Flos Chrysanthemi: the dry capitulum that derives from the feverfew chrysanthemum.Nature and flavor, sweet, bitter, be slightly cold.Return lung, Liver Channel.Performance characteristics: the wind heat clearing away of loosing, suppressing the hyperactive liver make eye bright.Be applied to conjunctival congestion and swelling pain, eyes is dim-sighted.
5, Semen Plantaginis: derive from the dry mature seed of Plantaginaceae plant Herba Plantaginis etc., nature and flavor: sweet, cold.Return kidney, liver, lung meridian.Performance characteristics: relieving stranguria by diuresis, antidiarrheal, liver heat removing and eyesight improving, removing heat from the lung and dissipating phlegm.Be applied to damp and hot dysuria, drench pain, edema.The liver-heat conjunctival congestion and swelling pain is joined the poor vision of invigorating the liver and kidney medicine treating the liver deficiency of the kidney void.
6, Spica Prunellae: the dry fruit ear that derives from the labiate Spica Prunellae.Nature and flavor: hot, bitter, cold.Return liver, gallbladder meridian.Performance characteristics: relieve inflammation or internal heat, make eye bright, eliminating stagnation, detumescence.Be applied to diseases such as conjunctival congestion and swelling pain, order pearl nyctalgia, hypertension.
7, Semen Cassiae: derive from the dry mature seed of leguminous plant Semen Cassiae, nature and flavor: sweet, bitter, be slightly cold.Return liver, large intestine channel.Performance characteristics: liver heat removing and eyesight improving, loosening bowel to relieve constipation.Be applied to the many tears of conjunctival congestion and swelling pain, photophobia, accumulation of heat or dryness of the intestine constipation due to liver-heat or the wind-heat of liver channel.
8, Radix Ginseng: the dry root that derives from the Araliaceae Radix Ginseng.Nature and flavor: sweet, little hardship, tepor.Return spleen, lung meridian.Performance characteristics: this product tepor is not and hot, and little hardship is not and dry, and merit is in QI invigorating, and the efficacy of a drug is quite strong.Both be good at strongly invigorating primordial QI and be the emergency treatment of collapse key medicine, again the gas of kind spleen reinforcing lung and promote the production of body fluid, calm the nerves, nourishing the brain and improving intelligence.
9, Fructus Corni: the drying and ripening sarcocarp that derives from Cornaceae plant Fructus Corni.Nature and flavor: acid, tepor.Return liver, kidney channel.Performance characteristics: the sour and astringent tepor of this product, the main Liver and kidney of returning, both kidney-replenishing, kidney tonifying essence, restrain again astringent or styptic treatment for spontaneous sweating, for flat nourishing YIN sun, mend and hold back and all product.What be applied to that Liver and kidney void loses has a dizzy spell diseases such as soreness of the waist and knees, sexual impotence.
10, Herba Dendrobii: the fresh or dry stem that derives from orchid dendrobium loddigesii Rolfe and Dendrobium nobile etc.Nature and flavor: sweet, be slightly cold.Return stomach, kidney channel, performance characteristics: the sweet cold of this product, go into the kind nourishing stomach-YIN of stomach, born fluid, go into the kind nourishing kidney-yin of kidney, clearind deficient heat.In addition, can also make eye bright, strong waist.Blurring of vision, waist knee joint weakness are used to suffer from a deficiency of the kidney.
11, Fructus Lycii: the dry mature fruit that derives from plant of Solanaceae lycium barbarum and Fructus Lycii.Nature and flavor: sweet, flat.Return liver, kidney, lung meridian.Performance characteristics: the sweet flat matter profit of this product, return the Liver and kidney warp, be good at nourishing the liver and kidney, make eye bright, be the treating the liver deficiency of the kidney yin, the common drug of visual deterioration.Be applied to having a dizzy spell of the hepatic and renal YIN deficiency, visual deterioration, the waist urushic acid is soft, pass out semen, quench one's thirst, deficiency of YIN chronic cough.
12, Semen Cuscutae: the dry mature seed that derives from convolvulus cuscuta plant or cuscuta japonica Choisy.Nature and flavor: hot, sweet, flat.Return the liver,kidney,spleen warp.Performance characteristics: the flat matter of this moral character profit, flat nourishing YIN sun, not only kidney-replenishing, kidney tonifying the moon, but also nourishing the liver to improve visual acuity, spleen reinforcing antidiarrheal, and the astringent or styptic treatment for spontaneous sweating energy of holding concurrently.Be applied to the poor vision of deficiency of the liver and kindey, insufficiency of the spleen loose stool or disease such as have loose bowels.
13, Fructus Ligustri Lucidi: the dry mature fruit that derives from Oleaceae plant Fructus Ligustri Lucidi.Nature and flavor: sweet, bitter, cool.Return liver, kidney channel.Performance characteristics: liver and kidney tonifying, clearing away heat to improve acuity of vision.Be applied to the visual deterioration of caused by liver and kidney deficiency.
14, Concha Haliotidis: this product derives from the shell of Bao Ke animal Haliotis diversicolor.Nature and flavor: salty, cold.Return Liver Channel.Performance characteristics: this product heat clearing away cold in nature, matter is heavily stayed under water, and specially goes into Liver Channel.Can suppressing the hyperactive liver and subsiding YANG, again can liver heat removing and eyesight improving, be order disease key medicine.Be applied to the dizzy margins of eyelids of excessive rising of liver-YANG, liver-fire conjunctival congestion cataracta, deficiency of the liver blurred vision.
15, Rhizoma Coptidis: the dry rhizome that derives from the ranunculaceae plant Rhizoma Coptidis.Nature and flavor: bitter, cold.GUIXIN, liver, kidney, large intestine channel.Performance characteristics: this product big bitter Great Cold, main GUIXIN stomach warp, double liver and the large intestine of returning, it is quite strong to rush down dampness, the efficacy of a drug clearly.Effect is the heart and middle burnt relatively, the fire of the kind stomach that clears away heart-fire, and a good appetite suddenly appearing in a serious disease Jiao is damp and hot, for controlling the key medicine of damp and hot fire stagnation.Be applied to bleeding due to blood-heat and tell nosebleed, cellulitis toxic swelling, conjunctival congestion and swelling pain, auditory meatus furuncle and phyma, herpes simplex rash.
16, Flos Eriocauli: the head inflorescence that derives from the dry zone scape of Eriocaulaceae plant Flos Eriocauli.Nature and flavor: hot, sweet, flat.Return liver, lung meridian.Performance characteristics: dispelling wind and heat pathogens, improving acuity of vision and removing nebula are applied to wind heat, conjunctival congestion, the photophobia that swells and ache, the nebula of looking unfamiliar film etc.
17, Caulis Akebiae: the dry rattan that derives from Lardizabalaceae plant threeleaf akebia or Caulis Akebiae.Nature and flavor: bitter, be slightly cold.GUIXIN, small intestinal, urinary bladder channel.Performance characteristics: it is strong that this product bitter cold must be let out power, both gone into bladder and relieving stranguria by diuresis, GUIXIN and small intestinal and clearing away heart-fire again, so heat conduction is descending damp and hot for controlling, drench bitterly and flaming up of heart-fire or move down the aphtha of the mouth and tongue of small intestinal, the key medicine of vexed dark coloured urine is applied to that pain is arrested on irritable feverish sensation in the chest, sore throat pharyngalgia, dark coloured urine, five types of stranguria, edema, the whole body, the amenorrhea breast is few.
18, Radix Rehmanniae Preparata: the process of preparing Chinese medicine processed goods that derives from Radix Rehmanniae.Nature and flavor: sweet, little wet.Return liver, kidney channel.Performance characteristics: nourishing YIN and supplementing blood, beneficial essence are filled out marrow, are applied to the hepatic and renal YIN deficiency, soreness of the waist and knees, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, disease such as severe palpitation, dizzy, tinnitus.
19, Rhizoma Dioscoreae: the dry rhizome that derives from Dioscoreaceae plant Rhizoma Dioscoreae.Nature and flavor: sweet, flat.Return spleen, lung, kidney channel.Performance characteristics: this product is sweet equals, returns spleen lung kidney channel.Can QI invigorating, again can yin nourishing, be the product of flat QI invigorating the moon.And take in puckery property concurrently, control the not solid disease of suffering from a deficiency of the kidney.
20, Rhizoma Alismatis: the dry tuber that derives from Rhizoma Alismatis plant Rhizoma Alismatis.Nature and flavor: sweet, light, cold.Return kidney, urinary bladder channel.Performance characteristics: this product sweet light cold in nature, return kidney and urinary bladder channel, it is both kind that to ooze diuretic wet, so the heat that can let out kidney and bladder again clearly is kind disease of controling the inferior the damp and hot and double heat of edema of Jiao.
21, Poria: the dry sclerotia that derives from Polyporaceae fungus Poria.Nature and flavor: sweet, light, flat, GUIXIN, spleen, kidney channel.Performance characteristics: the sweet light profit of oozing of this product, property is flat not inclined to one side, and double tonify deficiency.It is wet to ooze diuretic, again can the spleen invigorating mind calming.
22, Cortex Moutan: the dry root bark that derives from the cohosh Paeonia suffruticosa.Nature and flavor: bitter, hot, be slightly cold.GUIXIN, liver, kidney channel.Performance characteristics: for letting out the diffusing product of row clearly, both kind clearing away heat and cooling blood, kind again blood circulation promoting and blood stasis dispelling, also double reducing the asthenic fever has removing heat from blood and does not stay the stasis of blood, invigorates blood circulation and the characteristics of motionless blood.
23, Radix Rehmanniae: the fresh or dried root that derives from the Scrophulariaceae Radix Rehmanniae.Nature and flavor: sweet, bitter, cold.GUIXIN, liver, kidney channel.Performance characteristics: clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis.Be applied to consumption of YIN caused by febrile disease, excessive thirst, haematemesis, laryngopharynx swelling and pain fall in tongue.
24, Semen Arecae: the dry mature seed that derives from the babassu Semen Arecae.Nature and flavor: hot, bitter, wet.Return stomach, large intestine channel.Performance characteristics: the hot hardship of loosing of this product is fallen wet logical, returns stomach and large intestine channel.Kind parasite killing, the efficacy of a drug is quite strong, and the cathartic of holding concurrently, promotion polypide are discharged.
The objective of the invention is based on the traditional Chinese medical science various common ophthalmic pathogeny and Therapeutic Principle, on the basis of clinical proved recipe, through studying for a long period of time, is foundation with reference to modern medical theory and clinical experience.Get nourishing the liver and kidney, replenishing vital essence to improve eyesights such as Radix Rehmanniae Preparata, Rhizoma Dioscoreae, Radix Ginseng, Fructus Lycii, Fructus Corni, Herba Dendrobii, Fructus Ligustri Lucidi in the side, the Radix Rehmanniae, Cornu Saigae Tataricae clearing away heat and cooling blood YIN nourishing, Rhizoma Alismatis, Poria, Caulis Akebiae, Semen Arecae invigorating spleen for diuresis, Flos Eriocauli, Spica Prunellae, Concha Haliotidis liver heat removing and eyesight improving, the blood pressure lowering nebula removing; Full side 24 flavor Chinese herbal medicine are the merit of tool nourishing the liver and kidney, replenishing vital essence to improve eyesight, liver heat removing nebula removing, clearing away heat-damp and promoting diuresis altogether.At because the cataract due to hepatic and renal YIN deficiency, asthenia of essence and blood or insufficiency of the spleen mistake fortune and the stagnated heat of liver channel can improve vision, remove obstacles nebula removing and the treatment photophobia symptom effects such as photophobia, blurred vision of shedding tears are remarkable.
We are made up of 24 flavor Chinese medicinal ingredients, adopt advanced Chinese medicine processing extraction equipment, with advanced person's craft method, make and are convenient to oral pure Chinese medicinal preparation easy to carry.This medicine passes through Shaanxi Chinese medicine academy pharmacological research evidence: the present invention confirms through the acute toxicity test conclusion: behind mice lavage group medicine, LD50＞30g/kg of the present invention is equivalent to 200 times of people's usual amounts, proves that this medicine belongs to nontoxic level medicine.The long term toxicity test conclusion proves: after giving the rat gastric infusion, the present invention is (quite 50 times, 25 times, 5 times amounts of people's usual amounts) under used dosage, after irritating stomach group medicine in 90 days, to rat growth, hepatic and renal function, general signs, organ weight ratio value and internal organs perusal, tissue slice check result and matched group be no significant difference relatively all, do not find the overt toxicity reaction, also do not have the retardance toxic reaction, so clinical practice is safe and effective.
Pharmacodynamic test of active extract proves: the present invention relatively there is no obvious influence before to dog blood pressure, breathing, heart rate, electrocardiogram and administration.The present invention has the blood vessel dilating footpath and increases fluidised form power score value exempting from the bulbar conjunctiva blood capillary, the flow velocity effect of slowing down, and increase the expansion blood vessel and directly point out: the blood capillary capacity increases, just the blood capacity of returns increases, can promote blood to reflux, improve eye blood supply state, play and stablize the intraocular pressure effect.Also having xylol induced mice ear swelling has obvious antagonism (P＜0.05) to illustrate that this medicine has the antiinflammation of deciding to organizing exudative inflammation.
By above pharmacological evaluation, this medical instrument has than the effect of strong extension blood capillary, increases regional blood flow, microcirculation improvement, the active ingredient that has additional nutrients with trace element improves the whole and local physiological function of human body, increases the effect that removing nebula recovers vision of looking thereby reach to make eye bright.
Rich abundant nutrition in the medicament contg of the present invention, comprise rich vegetable protein matter, animal proteinum, aminoacid, biological activity, vitamins c, the plain B of little life, the plain E of little life and some trace element thereof can effectively improve the whole and local physiological function of human body, improve the eye microcirculation and reach, removing nebula increases looks the recovery vision, sanatory effect.
For further show the present invention to the treatment glaucoma, just, the clinical efficacy of several frequently seen ophthalmic such as mid-term cataract, optic atrophy etc., itemize some clinical datas and case below:
The present invention treats glaucoma 649 examples, and 1082 eyes account for 23.56%.Effectively: 344 eyes account for 31.78%; Invalid: 144 eyes account for 13.33%.Total effective rate is 86.67%, and the routine subjective symptoms of curing the disease all makes moderate progress, and toxic and side effects do not occur.
The present invention treats cataract 224 examples, 355 eyes, wherein women 135 examples, male 89 examples, eyes 132 examples, left eye 56 examples, right eye 36 examples.Age 30-40 year, 4 examples; 41-50 year, 27 examples; 51-61 year, 54 examples; 61-70 year, 125 examples; 14 examples more than 71 years old; The course of disease is the shortest 3 months, and is the longest 10 years.
Classification: senile cataract 201 examples; Initial phase 135 examples wherein; Immature phases 66 example; Concurrent natural disposition cataract 23 examples.
The observation of curative effect result is: nascent phase cataract 135 examples, produce effects 108 examples, effective 27 examples, total effective rate 100%.
Immature phase cataract 66 examples, produce effects 49 examples, effective 11 row, invalid 6 examples, total effective rate 91.6%.
Complicated cataract 23 examples, produce effects 7 examples, effective 10 examples, invalid 6 examples, total effective rate is 75%.The patient is many to be reached after 1 month effectively or the produce effects standard, and senile cataract in initial stage patient effective percentage is higher than the period of maturation, and inferior is the complicated cataract patient.
The present invention treats optic atrophy 106 examples, 145 eyes, and wherein 15 eyes of clinical cure account for 10%, imitate to show 51 eyes, account for 35.6%; Effective 51 eyes account for 35.6%; Effective 28 eyes account for 18.8%, and total effective rate is 81.2%.
The present invention is according to organic conception, and the principle of determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs is made has nourishing the liver and kidney, replenishing vital essence to improve eyesight, clearing away heat-damp and promoting diuresis, the effect of expelling wind and removing nebula.For both liver and kidney deficiency, the cataract that asthenia of essence and blood or insufficiency of the spleen mistake fortune and stagnated heat of liver channel etc. cause just, in and ophthalmic diseases such as optic atrophy, glaucoma, have the good clinical curative effect, curative effect is all good after patient's medication, can recover vision one to two course of treatment, reaches the recovery from illness effect.
Model case is introduced:
1, white clouds chapter, man, 64 years old, people from Xi'an, retired employees, see a doctor at the Xi'an ophthalmologic hospital in April, 92, and main suit's blurring of vision had the cloud shade more than 2 years, the inspection eyes are looked dumb outward, vitreous opacity, and cornea is crooked uneven, the intraocular pressure height, left vision is 0.01, and right eye 0.02 is diagnosed as cataract, after taking the present invention one to two course of treatment, cooperate eye stifling, the cloud shade mistake that fades day by day at the moment, course of treatment of back reuse, left vision reaches 0.8, and right eye reaches 1.0.
2, Li Wenying, the woman, 69 years old, people from Liuzhou, the teacher leaves one's post.The main suit once did operation for glaucoma twice at local certain hospital's right eye in October, 98, intraocular pressure can fall, and extracts eyeball, left eye at last, suffered from angle closure glaucoma 1 year, often headache, eyeball takes off bitterly and keeps in dark place visual deterioration, look into and press 35minHhg, vision 0.2, behind more than 20 bottle of the present invention of clothes, the transference cure that all are uncomfortable.Intraocular pressure is stabilized in 20minHhg always, vision restoration 0.6, and patient's Chinese medicine of the present invention of thanking you has brought bright Gospel for her.
3, fiber crops are full of chrysanthemum, woman 62 years old, people from Xi'an, suffering from glaucoma usually sheds tears secretly, two bottles of the present invention of clothes earlier have a try, and after medicine takes, have howed than presensation is comfortable, having bought 10 bottles again takes by explanation, adhered to taking medicine two months, eyes do not expand not bitterly, and it is clear to see that thing goes out, must look into to hospital, vision returns to 1.0 intraocular pressures by original 0.5,0.7 and reduces to normal value by original 38.
4, Hu Ying, woman 25 years old, the people of the Shaanxi Province Policy Research Office work of entrusting, eyes expanded and ached last year, headache, and binocular vision descends, right and left eyes is 0.1, influences work and study, and hospital diagnosis is an early-stage glaucoma, very worried, take 10 bottles of the present invention after, symptom fades away, vision restoration, present right eye 0.4, pressure relieve is filled with unbounded confidence to life at heart.
Embodiment 1:
Cornu Saigae Tataricae 1g Fructus Tribuli 40g Herba Equiseti Hiemalis 25g Flos Chrysanthemi 50g
Semen Plantaginis 25g Spica Prunellae 25g Semen Cassiae 40g Radix Ginseng 15g
Herba Dendrobii 40g Fructus Lycii 40g Semen Cuscutae 25g Fructus Ligustri Lucidi 25g
Concha Haliotidis 50g Rhizoma Coptidis 10g Flos Eriocauli 25g Caulis Akebiae 25g
Radix Rehmanniae Preparata 25g Rhizoma Dioscoreae 25g Rhizoma Alismatis 10g Poria 25g
Cortex Moutan 25g Radix Rehmanniae 25g Semen Arecae 25g Fructus Corni (system) 25g
Produce capsule its preparation process following steps:
More than 24 flavors, Fructus Tribuli, Herba Equiseti Hiemalis, Flos Chrysanthemi, Semen Plantaginis, Semen Cassiae, Fructus Corni, Herba Dendrobii are ground into fine powder, cross 100-120 mesh sieve, mixing, Cornu Saigae Tataricae, Radix Ginseng are ground into fine powder separately, cross 120 mesh sieves, again with above-mentioned fine powder mixing.Ten five tastes such as all the other Fructus Lycii decoct with water secondary, each two hours, collecting decoction filters, and being evaporated to relative density is the thick paste of 1.27-1.30 (80 ℃), with above-mentioned medicated powder mixing, drying, it is an amount of to pulverize, sieve, add adjuvant dextrin or starch, mixing, granulate, drying, 1000 of encapsulated one-tenth, promptly.
Embodiment 2:
Cornu Saigae Tataricae 2g Fructus Tribuli 45g Herba Equiseti Hiemalis 30g Flos Chrysanthemi 45g
Semen Plantaginis 30g Spica Prunellae 30g Semen Cassiae 35g Radix Ginseng 20g
Herba Dendrobii 35g Fructus Lycii 35g Semen Cuscutae 30g Fructus Ligustri Lucidi 35g
Concha Haliotidis 45g Rhizoma Coptidis 15g Flos Eriocauli 35g Caulis Akebiae 30g
Radix Rehmanniae Preparata 35g Rhizoma Dioscoreae 30g Rhizoma Alismatis 15g Poria 30g
Cortex Moutan 30g Radix Rehmanniae 35g Semen Arecae 30g Fructus Corni (system) 25g
Produce tablet its preparation process following steps:
With above 24 flavors, Fructus Tribuli, Herba Equiseti Hiemalis, Flos Chrysanthemi, Semen Plantaginis, Semen Cassiae, Fructus Corni, Herba Dendrobii is ground into fine powder, crosses 100-120 mesh sieve, mixing, Cornu Saigae Tataricae, Radix Ginseng are ground into fine powder separately and cross 120 mesh sieves, again with above-mentioned fine powder mixing, ten five tastes such as all the other Fructus Lycii decoct with water secondary, each two hours, collecting decoction, filtration, being evaporated to relative density is the thick paste of 1.27-1.30 (80 ℃), with above-mentioned fine powder mixing, granulates, the room temperature oven temperature is controlled at 60-70 ℃ of drying, compacting is in blocks, and sugar coating promptly can be made into tablet.
Embodiment 3:
Cornu Saigae Tataricae 3g Fructus Tribuli 50g Herba Equiseti Hiemalis 40g Flos Chrysanthemi 60g
Semen Plantaginis 40g Spica Prunellae 40g Semen Cassiae 50g Radix Ginseng 25g
Fructus Corni (system) 40g Herba Dendrobii 50g Fructus Lycii 50g Semen Cuscutae 40g
Fructus Ligustri Lucidi 40g Concha Haliotidis 60g Rhizoma Coptidis 25g Flos Eriocauli 40g
Caulis Akebiae 40g Radix Rehmanniae Preparata 40g Rhizoma Dioscoreae 40g Rhizoma Alismatis 25g
Poria 40g Cortex Moutan 40g Radix Rehmanniae 40g Semen Arecae 40g
The production technology preparation method can adopt the preparation method of embodiment 1 or embodiment 2.
Claims (6)
1, a kind of Chinese medicine for the treatment of person in middle and old age's eye disease is characterized in that: the medicament that the Chinese medicine of described treatment person in middle and old age eye disease is made by the raw material of following weight proportion: antelope's horn 1-3 part puncture vine 30-50 part scouring rush 20-40 part chrysanthemum 40-60 part plantain seed 20-40 part selfheal 20-40 part cassia seed 30-50 part ginseng 10-25 part Fructus Corni 20-40 part stem of noble dendrobium 30-50 part fruit of Chinese wolfberry 30-50 part seed of Chinese dodder 20-40 part fruit of glossy privet 20-40 part shell of seaear 40-60 part coptis 5-25 part pipewort 20-40 part akebi 20-40 part prepared rhizome of rehmannia 20-40 part Chinese yam 20-40 part rhizoma alismatis 5-25 part Poria cocos 20-40 part moutan bark 20-40 part glutinous rehmannia 20-40 part betel nut 20-40 part
2, a kind of Chinese medicine for the treatment of person in middle and old age's ocular disease according to claim 1 is characterized in that: the medicament that the Chinese medicine of described treatment person in middle and old age ocular disease is made by following materials of weight proportions:
50 parts of 25 parts of Flos Chrysanthemis of 40 parts of Herba Equiseties Hiemalis of 1 portion of Fructus Tribuli of Cornu Saigae Tataricae
15 parts of 40 parts of Radix Ginsengs of 25 parts of Semen Cassiaes of 25 parts of Spica Prunellaes of Semen Plantaginis
25 parts of 40 parts of Semen Cuscutae of 40 parts of Fructus Lycii of 25 parts of Herba Dendrobiis of Fructus Corni
25 parts of 10 parts of Flos Eriocaulis of 50 portions of Rhizoma Coptidis of 25 parts of Concha Haliotidis of Fructus Ligustri Lucidi
10 parts of 25 portions of Rhizoma Alismatis of 25 portions of Rhizoma Dioscoreaes of 25 parts of Radix Rehmanniae Preparata of Caulis Akebiae
25 parts of 25 portions of Semen Arecaes of 25 portions of Radix Rehmanniae of 25 parts of Cortex Moutans of Poria
3, a kind of Chinese medicine for the treatment of person in middle and old age's ocular disease according to claim 1 and 2 is characterized in that: described medicament is the above a dosage form of any pharmaceutics.
4, a kind of Chinese medicine for the treatment of person in middle and old age's ocular disease according to claim 3, it is characterized in that: described dosage form is tablet, capsule.
5, a kind of Chinese medicine for the treatment of person in middle and old age's ocular disease according to claim 4 is characterized in that: described dosage form is that the processing step of preparation method of tablet is as follows:
(1), Fructus Corni sprayed to mix thoroughly to steam with yellow wine form, standby;
(2), get that Fructus Tribuli, Herba Equiseti Hiemalis, Flos Chrysanthemi, Semen Plantaginis, Semen Cassiae, Fructus Corni, Herba Dendrobii are ground into 100-120 order fine powder, sieve, mixing;
(3), get Cornu Saigae Tataricae, Radix Ginseng and be ground into 120 order fine powders separately, again with above-mentioned steps (2) in 100-120 order fine powder mixing, standby;
(4), get ten five tastes such as all the other Fructus Lycii, decoct with water secondary, each two hours, collecting decoction filters, and being evaporated to temperature and being 80 ℃, relative density is the thick paste of 1.27-1.30, with above-mentioned steps (3) Chinese medicine powder mixing, right amount of auxiliary materials is pulverized, sieves, added to drying, mixing, granulate, drying, compacting is in flakes, sugar coating promptly can be made into tablet.
6, a kind of Chinese medicine for the treatment of person in middle and old age's ocular disease according to claim 4, it is characterized in that: described dosage form is that the processing step of capsular preparation method is as follows:
(1), Fructus Corni sprayed to mix thoroughly to steam with yellow wine form, standby;
(2), get that Fructus Tribuli, Herba Equiseti Hiemalis, Flos Chrysanthemi, Semen Plantaginis, Semen Cassiae, Fructus Corni, Herba Dendrobii are ground into 100-120 order fine powder, sieve, mixing;
(3), get Cornu Saigae Tataricae, Radix Ginseng and be ground into 120 order fine powders separately, again with above-mentioned steps (2) in 100-120 order fine powder mixing, standby;
(4), get ten five tastes such as all the other Fructus Lycii, decoct with water secondary, each two hours, collecting decoction, filter, being evaporated to temperature and being 80 ℃, relative density is the thick paste of 1.27-1.30, with above-mentioned steps (3) Chinese medicine fine powder mixing, dry, pulverize, sieve, add right amount of auxiliary materials, mixing is granulated, drying, encapsulated getting final product.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03108057 CN1453019A (en) | 2003-05-21 | 2003-05-21 | Chinese medicine for treating eye diseases of middle-aged and old people and its prepn |
| CNA2004100382483A CN1544072A (en) | 2003-05-21 | 2004-05-18 | Chinese traditional medicine for treating senile eye diseases and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03108057 CN1453019A (en) | 2003-05-21 | 2003-05-21 | Chinese medicine for treating eye diseases of middle-aged and old people and its prepn |
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| CN1453019A true CN1453019A (en) | 2003-11-05 |
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| CN 03108057 Pending CN1453019A (en) | 2003-05-21 | 2003-05-21 | Chinese medicine for treating eye diseases of middle-aged and old people and its prepn |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006131054A1 (en) * | 2005-06-04 | 2006-12-14 | Zichun Li | Chinese pharmaceutical ophthalmological formulations in forms of solutions, ointments and pills for antiaging recovery |
| CN100566740C (en) * | 2006-03-15 | 2009-12-09 | 吴佳勋 | A kind of Chinese herb medicine of preventing and treating myopia |
| CN101773653A (en) * | 2010-04-20 | 2010-07-14 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicine composition for treating ablepsia and preparation method thereof |
| CN101647913B (en) * | 2009-09-04 | 2011-06-15 | 任健 | Traditional Chinese medicine preparation for treating senile cataract and viral keratitis |
| CN101028388B (en) * | 2007-04-04 | 2011-08-10 | 西安碑林药业股份有限公司 | Quality inspection of Chinese-medicinal preparation for treating shortsighness and asthenopia |
| CN102755549A (en) * | 2012-07-16 | 2012-10-31 | 耿祥娥 | Drug for curing cataract and preparation method thereof |
| CN102940753A (en) * | 2012-12-04 | 2013-02-27 | 刘顺慧 | Pills for treating glaucoma and preparation method |
| CN105663477A (en) * | 2016-02-29 | 2016-06-15 | 高阳 | Traditional Chinese medicine composition for treating intraocular hypertension symptoms |
| CN111467436A (en) * | 2020-05-22 | 2020-07-31 | 沈阳东新药业有限公司 | Therapeutic application of fuming capsule |
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2003
- 2003-05-21 CN CN 03108057 patent/CN1453019A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006131054A1 (en) * | 2005-06-04 | 2006-12-14 | Zichun Li | Chinese pharmaceutical ophthalmological formulations in forms of solutions, ointments and pills for antiaging recovery |
| CN100566740C (en) * | 2006-03-15 | 2009-12-09 | 吴佳勋 | A kind of Chinese herb medicine of preventing and treating myopia |
| CN101028388B (en) * | 2007-04-04 | 2011-08-10 | 西安碑林药业股份有限公司 | Quality inspection of Chinese-medicinal preparation for treating shortsighness and asthenopia |
| CN101647913B (en) * | 2009-09-04 | 2011-06-15 | 任健 | Traditional Chinese medicine preparation for treating senile cataract and viral keratitis |
| CN101773653A (en) * | 2010-04-20 | 2010-07-14 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicine composition for treating ablepsia and preparation method thereof |
| CN102755549A (en) * | 2012-07-16 | 2012-10-31 | 耿祥娥 | Drug for curing cataract and preparation method thereof |
| CN102755549B (en) * | 2012-07-16 | 2013-09-25 | 耿祥娥 | Drug for curing cataract and preparation method thereof |
| CN102940753A (en) * | 2012-12-04 | 2013-02-27 | 刘顺慧 | Pills for treating glaucoma and preparation method |
| CN105663477A (en) * | 2016-02-29 | 2016-06-15 | 高阳 | Traditional Chinese medicine composition for treating intraocular hypertension symptoms |
| CN111467436A (en) * | 2020-05-22 | 2020-07-31 | 沈阳东新药业有限公司 | Therapeutic application of fuming capsule |
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