CN1413653A - Chinese drugs for treating cardiovascular and cerebrovascular system disease and its preparation method - Google Patents
Chinese drugs for treating cardiovascular and cerebrovascular system disease and its preparation method Download PDFInfo
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Abstract
A Chinese medicine for treating cardiovascular and cerebrovascular diseases, such as apoplexy sequela, epilepsy, myocardial infarction, coronary heart disease, etc. is prepared from more than 27 Chinese-medicinal materials including musk, beer gall, borneol, etc through pulverizing part of them, proportionally mixing with beer gall and buffalo horn, sterilizing at 100-110 deg.C, and adding musk, borneol and adhesive. Its advantages are high cure rate, less recurrence and no toxic by-effect.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of cardiovascular and cerebrovascular disease, particularly a kind of is the Chinese medicine of raw material for treating diseases of cardiovascular and cerebrovascular systems with the Chinese crude drug, the invention still further relates to this preparation method of Chinese medicine.
Background technology
In recent years, the embolic cerebrovascular, the cardiovascular system diseases that cause because of hyperlipidemia, atherosclerosis etc. are becoming a kind of commonly encountered diseases, frequently-occurring disease, human health has been constituted very big threat, especially for middle-aged and elderly people, its a kind of especially sickness rate is the highest, and the disease of its life of serious harm.For this reason, solve the thromboembolism problems of dissolution, effectively cure diseases of cardiovascular and cerebrovascular systems such as apoplexy, heart infarction, coronary heart disease, improve level of human health, become the problem of the common concern of medical profession scientific research personnel.
The medicine of using more treatment cardiovascular and cerebrovascular disease in China clinically is generally blood vessel dilating class medicine, this class medicine is generally Western medicine, and temporarily channel of blood flow in the blood vessel dilating easily causes side effect such as headache when vasodilation, thrombosis is eliminated in dissolving do not had effective function.The another kind of medicine of Ying Yonging then is the medicine with thrombolytic effect clinically, be called the medicine of thrombosis sheet etc. as commodity, though this class medicine can have certain dissolution to thrombosis, but its effective percentage is lower, generally about 80%, and these medicines are Western medicine, easily produce because of diluting thrombus and cause patient's blood platelet reduction, wound bleeding is difficult for stopping, coagulation problem, has certain toxic and side effects, and still have bounce-back after the drug withdrawal, and this class medicine is less for the effect of old thrombosis, not remarkable to the therapeutical effect of cerebral infarction sequela.
Chinese patent literature CN1061537C discloses a kind of hyperlipidemia and cardiovascular and cerebrovascular diseases associated monascus preparation (a kind of Chinese medicine) for the treatment of, it contains the Monas cuspurpureus Went with blood fat reducing, function of promoting blood circulation to disperse blood clots that monascus ruber strain that a kind of utilization specially filters out is made, in preparation process, need the specific culture fluid of preparation, and control its pH value between 2.5-8.0, at 121 ℃ of following high temperature sterilizes, and need to cultivate more than 4 days reuse ethanol extraction, evaporation and concentration at 7-35 ℃ of bottom fermentation.Therefore its weak point is, preparation technology is comparatively complicated, and the cycle is longer, and it only is 34.2% for the effective percentage that reduces atherogenic index, and is not very good to the curative effect of cardiovascular and cerebrovascular disease.
Another piece Chinese patent literature CN1086586C discloses a kind of medicine for the treatment of cardiovascular and cerebrovascular disease and preparation method thereof, it is by Radix Angelicae Sinensis, Bulbus Fritillariae Cirrhosae, Radix Paeoniae Rubra, Flos Carthami, Herba Schizonepetae, Herba Ephedrae, Radix Saposhnikoviae, Rhizoma Atractylodis, Fructus Forsythiae, Radix Platycodonis, Radix Glycyrrhizae, Herba Menthae, Radix Scutellariae, Radix Puerariae, unpeeled CORTEX MOUTAN, Radix Polygoni Multiflori, Radix Et Rhizoma Rhei, Natrii Sulfas, Fructus Gardeniae, the Radix Rehmanniae, Radix Rubiae, Rhizoma Cyperi, Radix Scrophulariae, Talcum, Gypsum Fibrosum and Os Draconis are that raw material is formulated in proportion, said by its description, it is 95.5% to the effective percentage of coronary heart disease, and only be 85% to the effective percentage of the comparatively obstinate disease apoplexy sequela of thrombosis, and its case that is applied to treat above-mentioned two kinds of diseases is very few, this is enough to illustrate that it is at apoplexy sequela, the clinical practice of the stubborn disease that thrombosis such as epilepsy are more outmoded is insufficient, so its therapeutic effect is still not satisfactory.
Summary of the invention
The objective of the invention is to, overcome above-mentioned the deficiencies in the prior art, and provide that a kind of thrombolytic thromboembolism preventing power is strong, cure rate is high, can effectively treat the Chinese medicine of the heavier treatment of conditions diseases of cardiovascular and cerebrovascular systems due to the old thrombosis.
Another object of the present invention is, a kind of method for preparing the Chinese medicine of above-mentioned treatment diseases of cardiovascular and cerebrovascular systems is provided.
In order to achieve the above object, the solution that the present invention takes is that the Chinese medicine of treatment diseases of cardiovascular and cerebrovascular systems involved in the present invention is the medicament of being made by the raw material that mainly contains following weight proportioning (being weight portion):
Calculus Bovis 1-20 part Radix Codonopsis 15-25 part Fructus Amomi 10-20 part
Cornu Bubali powder 5-15 part Radix Paeoniae Rubra 12-25 part Herba speranskiae tuberculatae 12-25 part
Moschus 1-10 part Indigo Naturalis 8-18 part Pericarpium Citri Reticulatae Viride 12-25 part
Fel Ursi 2-12 part Radix Scrophulariae 12-25 part Folium Isatidis 12-20 part
Radix Angelicae Sinensis 10-25 part Radix Isatidis 12-25 part Herba Taraxaci 12-20 part
Radix Rehmanniae 10-25 part Picrorhiza scrophulariiflora 12-25 part SHANZHIZI 15-30 part
Flos Lonicerae 10-25 part Semen Platycladi 15-25 part Borneolum Syntheticum 6-15 part
Fructus Forsythiae 12-25 part baked polygonum capitatum 15-25 part Periostracum Cicadae 12-25 part
Radix Pseudostellariae 12-20 part Endothelium Corneum Gigeriae Galli 15-25 part Radix Aucklandiae 15-30 part
Above-mentioned baked polygonum capitatum is the Radix Polygoni Multiflori of ripening, and described SHANZHIZI is also referred to as Fructus Gardeniae.
In order to strengthen curative effect, Chinese medicine of the present invention also contains the raw material of following weight proportioning (being weight portion): Radix Arnebiae (Radix Lithospermi) 12-25 part Fructus Amomi Rotundus 10-20 part.
In order further to improve its curative effect again, Chinese medicine of the present invention also contains the raw material of following weight proportioning (being weight portion) except that Radix Arnebiae (Radix Lithospermi) that contains above-mentioned weight proportion and Fructus Amomi Rotundus: Rhizoma Belamcandae 10-20 part.Certainly when not adding the Radix Arnebiae (Radix Lithospermi) of described weight proportion, Fructus Amomi Rotundus, also can add the Rhizoma Belamcandae of above-mentioned weight proportion, Chinese medicine of the present invention also can only add any one in Radix Arnebiae (Radix Lithospermi), Fructus Amomi Rotundus, the Rhizoma Belamcandae, no longer describes in detail herein.
Each raw material components of Chinese medicine of the present invention and preferred weight proportioning (weight portion) scope thereof are:
Calculus Bovis 2-10 part Radix Paeoniae Rubra 15-22 part Pericarpium Citri Reticulatae Viride 15-20 part
Cornu Bubali powder 8-12 part Indigo Naturalis 10-15 part Folium Isatidis 12-18 part
Moschus 3-8 part Radix Scrophulariae 15-20 part Herba Taraxaci 15-20 part
Fel Ursi 3-8 part Radix Isatidis 15-20 part SHANZHIZI 20-25 part
Radix Angelicae Sinensis 15-20 part Picrorhiza scrophulariiflora 15-20 part Borneolum Syntheticum 6-12 part
Radix Rehmanniae 15-20 part Semen Platycladi 15-20 part Periostracum Cicadae 15-20 part
Flos Lonicerae 15-20 part baked polygonum capitatum 15-20 part Radix Aucklandiae 15-20 part
Fructus Forsythiae 15-20 part Endothelium Corneum Gigeriae Galli 15-22 part Radix Arnebiae (Radix Lithospermi) 15-20 part
Radix Pseudostellariae 15-18 part Fructus Amomi 12-18 part Fructus Amomi Rotundus 12-18 part
Radix Codonopsis 15-20 part Herba speranskiae tuberculatae 15-20 part Rhizoma Belamcandae 12-18 part
Above-mentioned each raw material optimum weight proportioning (being weight portion) of Chinese medicine of the present invention is:
18 parts on 20 parts of Pericarpium Citri Reticulatae Virides of 6 parts of Radix Paeoniae Rubra of Calculus Bovis
16 parts of 12 portions of Folium Isatidiss of 10 parts of Indigo Naturaliss of Cornu Bubali powder
16 parts of 18 parts of Herba Taraxacis of 4 portions of Radix Scrophulariaes of Moschus
22 parts of 18 parts of SHANZHIZI of 4 parts of Radix Isatidiss of Fel Ursi
8 parts of 18 parts of Borneolum Syntheticums of 18 parts of Picrorhiza scrophulariifloras of Radix Angelicae Sinensis
18 parts of 18 parts of Periostracum Cicadae of 18 parts of Semen Platycladi of the Radix Rehmanniae
18 parts of 18 parts of Radix Aucklandiae of 16 parts of baked polygonum capitatums of Flos Lonicerae
18 parts of 20 portions of Radix Arnebiae (Radix Lithospermi)s of 18 parts of Endothelium Corneum Gigeriae Galli of Fructus Forsythiae
15 parts in 15 parts of Fructus Amomi Rotunduss of 16 parts of Fructus Amomis of Radix Pseudostellariae
15 parts of 18 parts of Rhizoma Belamcandae of 18 parts of Herba speranskiae tuberculataes of Radix Codonopsis
Above-mentioned said umber is weight portion, and its unit can be unit of weights such as gram, two, money, jin, kilogram, ton.
The medicament of the Chinese medicine of the present invention that above-mentioned each materials of weight proportions is made is said any dosage form on the pharmaceutics, but generally with honeyed pill dosage form or capsule formulation for well.
Solution of the present invention is based on Chinese medicine and pharmacy to pathogenetic understanding of diseases of cardiovascular and cerebrovascular systems and Therapeutic Principle, from Chinese traditional medicine treasure-house, filter out and have acupuncture-stimulating blood stasis dispersing, remove the rotten and let fresh grow, consciousness-restoring and orifice-opening, repair neural, benefiting essence and marrow, the edible Chinese crude drug of integration of edible and medicinal herbs, by the theory of Chinese medical science prescription, make its performance promote cell metabolism, microcirculation improvement, blood viscosity lowering, thrombus, remove refuse in the blood, antiplatelet aggregation, defeated logical blood circulation passage, and then reach effective elimination source of disease, cure the purpose of the various diseases that causes because of the cardiovascular and cerebrovascular vessel thromboembolism.
Above-mentioned each prescription raw material is made preparation method of Chinese medicine of the present invention is, preparation as follows: 1. get Moschus, Borneolum Syntheticum, Fel Ursi and Cornu Bubali powder described each raw material in addition earlier, clean, subsequently above-mentioned each raw material of cleaning is dried, pulverized, be ground into 100 orders-180 purpose fine powder, described each fine powder raw material and Fel Ursi, Cornu Bubali powder are prepared burden, mixed by described weight proportion (weight portion), stir, obtain elementary mixed material; Perhaps take by weighing Moschus, Borneolum Syntheticum, Fel Ursi, Cornu Bubali powder described each raw material in addition by described weight proportion earlier, clean, mix, the material that each raw material of cleaning is mixed is dried subsequently, be ground into 100 orders-180 purpose fine powder, then with claim by described weight proportion Fel Ursi, Cornu Bubali powder mix, stir, obtain described elementary mixed material; 2. the above-mentioned elementary mixed material that stirs is carried out ripening, sterilization treatment 10-40 minute under 100 ℃～110 ℃ temperature, the Moschus and the Borneolum Syntheticum that add the process sterilization treatment then by described weight proportion, add suitable amount of adhesive, mix homogeneously in 5 minutes is made the medicament of required dosage form.When needs are made the honeyed pill dosage form, it is that the honey aqueous solution of 30%-70% (volume) such as concentration are 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70% etc. that then above-mentioned binding agent adopts concentration, add an amount of above-mentioned honey aqueous solution in the material that is mixed toward described each raw material, mix homogeneously in 5 minutes, molding are made the medicament of honeyed pill dosage form; When needs are made into capsule formulation, it is the ethanol water of 10%-40% (volume) that then above-mentioned binding agent adopts concentration, in being mixed uniform material, described each raw material adds an amount of above-mentioned ethanol water, mix homogeneously, make the granule of 20 orders-60 order size, oven dry incapsulates, and makes said capsule formulation on the pharmaceutics.
The ratio of the weight of the material that the honey aqueous solution of the 30%-70% that is added (volume) and each raw material are mixed is 0.1-0.2: 1, the ratio of the weight of the material that the ethanol water of the above-mentioned 10%-40% (volume) that is added and above-mentioned each raw material are mixed is 0.1-0.2: 1, when making the honeyed pill dosage form, each honeyed pill weighs 1.0 grams, when making capsule formulation, then each capsule weighs 0.5 gram.Chinese medicine pill of the present invention can be called purify the blood pill or blood-cleaning pill, and capsule then can be called the capsule that purifies the blood.
Described Moschus and Fel Ursi are all taken from artificial a large amount of Moschus moschiferous of culturing and are cultured Bears.
Chinese medicine of the present invention can also contain the component that Radix Puerariae, Fructus Crataegi etc. are of value to patient's rehabilitation, and technique scheme also belongs to protection scope of the present invention, no longer describes in detail herein.
The instructions of taking of Chinese medicine pill of the present invention is: take 4 balls totally 4 grams at every turn, take every day three times; The instructions of taking of Chinese medicinal capsule of the present invention is: take 8 capsules totally 4 grams at every turn, take every day three times.
The curative effect of Chinese medicine of the present invention can obtain proof in clinic trial.Chinese medicine of the present invention begins at the treatment cerebrovascular disease on probation clinically from March, 1998, to 120 routine cerebral infarction sequela patients on probation altogether in March calendar year 2001, male's 68 examples wherein, women's 52 examples, the oldest person 76 years old, reckling 37 years old, 48 years old mean age, medication dose is: each 4 grams (honeyed pill of 4 balls, 1.0 grams or 8 0.5 gram capsules), every day three times, early, middle and late each once, took medicine 4 months, and make curative effect comparision with the thrombosis sheet simultaneously, thrombosis sheet Time of Administration also is 4 months, be 1 year observing time, judge that efficacy criteria is:
(1) recovery from illness: after taking medicine 4 months, patient's activity is not seen thromboembolism sequela symptom within 1 year freely;
(2) produce effects: after taking medicine 4 months, the thromboembolism sequela obviously alleviates, but walking is not also not freely.
(3) effective: 4 months diseases of taking medicine alleviate, recurrence again after the drug withdrawal;
(4) invalid: the back disease of taking medicine does not have change.
Chinese medicine of the present invention sees following table for details with the curative effect comparision data of contrast medicine thrombosis sheet.(the treatment disease is cerebral infarction sequela).
| Medication | The observation number of taking medicine | The recovery from illness number | Cure rate | The produce effects number | Effective number | Invalid number | Total effective rate |
| Chinese medicine of the present invention | 120 | 116 | 96.6％ | ??2 | ??1 | ??1 | ??99.2％ |
| The thrombosis sheet | 120 | 43 | 35.8％ | ??45 | ??17 | ??15 | ??87.5％ |
Based on above higher cure rate, herbal medicine efficacy of the present invention is described significantly, lastingly, for dissolving old thrombosis obvious effect is arranged, than prior art very much progress is arranged at the heavier cerebrovascular disease of treatment symptom.
From August in August, 1998 to calendar year 2001, Chinese medicine of the present invention is used for the treatment of 120 routine myocardial infarction patients clinically, wherein male's 65 examples, women's 55 examples, took medicine 4 months, medication dose is every day three times, and each 4 grams (honeyed pill of 4 balls, 1.0 grams or the capsules of 8 0.5 grams) were observed 1 year, have 113 example recoveries from illness, 4 routine produce effects, 2 examples are effective, and 1 example is invalid, its cure rate is 94.2%, and total effective rate is 99.2%.More than said recovery from illness be meant that thrombosis dissolves, clinical symptom disappearance was observed 1 year, life freely, no discomfort uncomfortable in chest, nervous; Produce effects is meant that clinical symptoms obviously alleviates, but also has slight uncomfortable sensation; Effectively be meant clinical symptom relief, but still feel uncomfortable in chest after the drug withdrawal, have palpitation, feel suffocated; The invalid no tangible disease of taking medicine that is meant alleviates sign.Clinic trial result shows that Chinese medicine of the present invention has higher cure rate to myocardial infarction, has confirmed its significant curative effect aspect the treatment cardiovascular disease, and lasting medicine, and curative effect is obvious, is better than other similar medicine.
Through clinical observation 3 years, and visit patient 20 people that take medicine continuously about 6 months to 1 year, confirm that the patient does not produce any bad and uncomfortable reaction because of taking Chinese medicine of the present invention, and its appetite increases, immunity increases, so clinic trial proves that Chinese medicine of the present invention does not have toxic and side effects.Owing to when Chinese medicine of the present invention is used for the treatment of serious symptom such as cerebral embolism (apoplexy) sequela, myocardial infarction, all have higher cure rate and effective percentage, then just more unquestionable with its disease such as hypertension, hyperlipidemia for the treatment of light disease, no longer describe in detail herein.
To contain the Radix Arnebiae (Radix Lithospermi) of above-mentioned weight proportion and the Chinese medicine of the present invention of Fructus Amomi Rotundus August in May, 2000 to calendar year 2001 and be used for the treatment of 80 routine myocardial infarction patients clinically, male's 46 examples wherein, women's 34 examples, 1 month all patient that takes medicine promptly has manifest symptom to alleviate sign, takes medicine 78 example recoveries from illness 3 months, 2 routine produce effects, cure rate is 97.5%, total effective rate 100%, and also shorten to some extent the course of treatment.The clinical use of Chinese medicine of the present invention proves, add Radix Arnebiae (Radix Lithospermi), Fructus Amomi Rotundus after because it has and improves the stomach function, strengthens gastric motility, improves the effect of immunity, Gu and help patient's rehabilitation more, thereby shortened the course of treatment to some extent, cure rate increases.The above-mentioned patient who is cured does not have repeatedly through visiting 1 year, and Chinese medicine of the present invention has no side effect.Therefore, behind adding Radix Arnebiae (Radix Lithospermi) and the Fructus Amomi Rotundus, make Chinese medicine of the present invention have even more ideal therapeutic effect.
August in June, 2000 to calendar year 2001, will contain the Chinese medicine of the present invention of Radix Arnebiae (Radix Lithospermi), Fructus Amomi Rotundus and the Rhizoma Belamcandae of above-mentioned weight proportion, be used for the treatment of myocardial infarction patient 80 examples clinically, male's 42 examples wherein, women's 38 examples.Took medicine 1 month, all conditions of patients all take an evident turn for the better, took medicine 2 months, and then 79 example recoveries from illness, 1 routine produce effects, cure rate reaches 98.75%, total effective rate 100%, further shorten the course of treatment.Above clinical trial certificate, adding has after the Rhizoma Belamcandae of liver protection effect, more helps rehabilitation of patients, and observes confirmation in a year, and this Chinese medicine has no side effect, and therefore, behind the adding Rhizoma Belamcandae, the therapeutic effect of Chinese medicine of the present invention is more remarkable.
Clinic trial result shows that Chinese medicine of the present invention has following advantage:
1, to eat homologous Chinese crude drug be raw material in drug of choice of the present invention, and the Chinese prescription that each raw material is made into meets the drug matching rule of respectively distinguishing the flavor of, and utilizes the comprehensive function of the Chinese medicine of respectively distinguishing the flavor of, and the treatment diseases of cardiovascular and cerebrovascular systems through the clinic trial checking, has no side effect to human body.
2, Chinese medicine of the present invention need not to decoct, do not aviod certain food, and taking convenience, and do not have harsh processing conditions in its preparation process, preparation technology is simple.
3, Chinese medicine of the present invention adopts the Chinese crude drug preparation, through clinic trial, prove its effectively blood viscosity lowering, thrombolytic thromboembolism preventing ability is strong, cure rate height, non-relapse after healing, efficacy consolidation, especially to the old thrombosis dissolve effect significantly, curative effects such as cardiovascular and cerebrovascular disease such as the heavier apoplexy sequela of the disease that causes for thrombosis, myocardial infarction, coronary heart disease are obvious, then curative effect is more remarkable for diseases such as the lighter hypertension of symptom, hyperlipidemia.
4, therefore Chinese medicine of the present invention can effectively strengthen body immunity and appetite owing to have the effect of dredge the meridian passage, blood stasis dispersing and fresh blood promoting, microcirculation improvement, promotion cell metabolism, helps the quick rehabilitation of patient.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment, and these will help the understanding of the present invention, but the present invention is not subjected to the qualification of these embodiment, and its protection domain is decided by claims.
The Chinese medicine of embodiment 1, the described treatment diseases of cardiovascular and cerebrovascular systems of present embodiment is the Chinese medicine preparation made from each raw material of following weight proportioning, takes by weighing each raw material (kilogram) by following weight proportion:
Calculus Bovis 1 Radix Codonopsis 15 Fructus Amomis 20
Cornu Bubali powder 5 Radix Paeoniae Rubra 12 Herba speranskiae tuberculataes 25
Moschus 1 Indigo Naturalis 18 Pericarpium Citri Reticulatae Virides 12
Fel Ursi 2 Radix Scrophulariaes 25 Folium Isatidiss 12
Radix Angelicae Sinensis 25 Radix Isatidiss 12 Herba Taraxacis 20
The Radix Rehmanniae 25 Picrorhiza scrophulariifloras 25 SHANZHIZI 15
Flos Lonicerae 25 Semen Platycladi 15 Borneolum Syntheticums 6
Fructus Forsythiae 25 baked polygonum capitatums 15 Periostracum Cicadaes 25
Radix Pseudostellariae 12 Endothelium Corneum Gigeriae Galli 15 Radix Aucklandiae 15
Its preparation method is:
Get Moschus earlier, Borneolum Syntheticum, described each raw material beyond Fel Ursi and the Cornu Bubali powder, clean, be to clean with clear water herein, subsequently above-mentioned each raw material of cleaning is dried, pulverize, be ground into 100 purpose fine powders, with described each fine powder raw material and Fel Ursi, Cornu Bubali powder is prepared burden by above-mentioned weight proportion (kilogram), mix, stir, under 100 ℃～110 ℃ temperature, carry out ripening afterwards, sterilization treatment 30 minutes, the Moschus and the Borneolum Syntheticum (Moschus of Jia Ruing and Borneolum Syntheticum are fine-powdered herein) that add the process sterilization treatment then by above-mentioned weight proportion (kilogram), add suitable amount of adhesive, mix homogeneously in 5 minutes is made the medicament of required dosage form.The described binding agent of present embodiment is that concentration is the honey aqueous solution of 40% (volume), in the material that described each raw material is mixed, add an amount of above-mentioned honey aqueous solution, mix homogeneously in 5 minutes, molding are made the medicament of honeyed pill dosage form, and each close ball weighs 1.0 grams.Above-mentioned peak mulse solution is 0.15: 1 with the ratio of the weight of material that described each raw material is mixed.
The Chinese medicine of embodiment 2, the described treatment diseases of cardiovascular and cerebrovascular systems of present embodiment is the Chinese medicine preparation made from each raw material of following weight proportioning, takes by weighing each raw material (kilogram) by following weight proportion:
Calculus Bovis 20 Radix Codonopsis 25 Fructus Amomis 10
Cornu Bubali powder 15 Radix Paeoniae Rubra 25 Herba speranskiae tuberculataes 12
Moschus 10 Indigo Naturaliss 8 Pericarpium Citri Reticulatae Virides 25
Fel Ursi 12 Radix Scrophulariaes 12 Folium Isatidiss 20
Radix Angelicae Sinensis 10 Radix Isatidiss 25 Herba Taraxacis 12
The Radix Rehmanniae 10 Picrorhiza scrophulariifloras 12 SHANZHIZI 30
Flos Lonicerae 10 Semen Platycladi 25 Borneolum Syntheticums 15
Fructus Forsythiae 12 baked polygonum capitatums 25 Periostracum Cicadaes 12
Radix Pseudostellariae 20 Endothelium Corneum Gigeriae Galli 25 Radix Aucklandiae 30
Its preparation method is:
Get Moschus, Borneolum Syntheticum, Fel Ursi and Cornu Bubali powder described each raw material in addition earlier, clean, subsequently above-mentioned each raw material of cleaning is dried, be ground into 100 orders-180 purpose fine powder, be 120 orders herein.Described each fine powder raw material and Fel Ursi, Cornu Bubali powder are prepared burden, mixed by above-mentioned weight proportion (kilogram), stir, under 100 ℃～110 ℃ temperature, carried out ripening, sterilization treatment 35 minutes afterwards, the Moschus and the Borneolum Syntheticum that add the process sterilization treatment then by above-mentioned weight proportion (kilogram), add suitable amount of adhesive, mix homogeneously in 5 minutes is made the medicament of required dosage form.The described binding agent of present embodiment is that concentration is the honey aqueous solution of 50% (volume), in the material that described each raw material is mixed, add an amount of above-mentioned honey aqueous solution, mix homogeneously in 5 minutes, molding are made the medicament of honeyed pill dosage form, and each close ball weighs 1.0 grams.The ratio of the weight of the material that above-mentioned honey aqueous solution addition and described each raw material are mixed is 0.2: 1.
The Chinese medicine of the treatment diseases of cardiovascular and cerebrovascular systems of embodiment 3, present embodiment is the Chinese medicine preparation made from each raw material of following weight proportioning, takes by weighing each raw material (kilogram) by following weight proportion:
Calculus Bovis 10 Radix Codonopsis 20 Fructus Amomis 15
Cornu Bubali powder 10 Radix Paeoniae Rubra 18 Herba speranskiae tuberculataes 18
Moschus 6 Indigo Naturaliss 13 Pericarpium Citri Reticulatae Virides 18
Fel Ursi 7 Radix Scrophulariaes 18 Folium Isatidiss 16
Radix Angelicae Sinensis 18 Cymbidium ensifolium (L.) Sw. root 18 Herba Taraxacis 16
The Radix Rehmanniae 18 Picrorhiza scrophulariifloras 18 SHANZHIZI 22
Flos Lonicerae 17 Semen Platycladi 20 Borneolum Syntheticums 10
Fructus Forsythiae 20 baked polygonum capitatums 20 Periostracum Cicadaes 18
Radix Pseudostellariae 16 Endothelium Corneum Gigeriae Galli 20 Radix Aucklandiae 23
Its preparation method is:
Get Moschus earlier, Borneolum Syntheticum, described each raw material beyond Fel Ursi and the Cornu Bubali powder, clean, mix, the material that above-mentioned each clean raw material is mixed is dried subsequently, be ground into 100 purpose fine powders, then with claim by above-mentioned weight proportion (kilogram) Fel Ursi (powdery), Cornu Bubali powder is prepared burden by above-mentioned weight proportion (kilogram), mix, stir, obtain elementary mixture, under 100 ℃～110 ℃ temperature, it is carried out ripening afterwards, sterilization treatment 40 minutes, the Moschus and the Borneolum Syntheticum (fine-powdered) that add the process sterilization treatment then by above-mentioned weight proportion (kilogram), add suitable amount of adhesive, mix homogeneously in 5 minutes is made the medicament of required dosage form.The described binding agent of present embodiment is that concentration is the honey aqueous solution of 30% (volume), add an amount of above-mentioned honey aqueous solution in the material that is mixed toward described each raw material, mix homogeneously in 5 minutes, molding are made the medicament of honeyed pill dosage form, and each close ball weighs 1.0 grams.The addition of above-mentioned honey aqueous solution is 0.1: 1 with the ratio of the weight of the described material addition that is mixed.
Embodiment 4, Chinese medicine of the present invention also will take by weighing and allocate into following two kinds of raw materials (kilogram) except that take by weighing each raw material (kilogram) by each raw material weight proportioning described in the embodiment 1:
12 kilograms of Radix Arnebiae (Radix Lithospermi)s, 10 kilograms in Fructus Amomi Rotundus.
Its preparation method is:
Described each raw material of getting earlier beyond the Moschus, Borneolum Syntheticum, Fel Ursi, Cornu Bubali powder is cleaned with clear water, subsequently above-mentioned each raw material of cleaning is dried, is pulverized, and is ground into 100 orders-180 purpose fine powder, is 150 purpose fine powders herein.Described each fine powder raw material and Fel Ursi, Cornu Bubali powder are prepared burden, mixed by above-mentioned weight proportion (kilogram), stir, under 100 ℃～110 ℃ temperature, carried out ripening, sterilization treatment 20 minutes afterwards, the Moschus and the Borneolum Syntheticum (fine-powdered) that add the process sterilization treatment then by above-mentioned weight proportion, add suitable amount of adhesive, mix homogeneously in 5 minutes is made the medicament of required dosage form.Binding agent in the present embodiment is that concentration is the honey aqueous solution of 70% (volume), adds an amount of above-mentioned honey aqueous solution in the material that is mixed toward described each raw material, mix homogeneously in 5 minutes, and the medicament of honeyed pill dosage form is made in molding, and each honeyed pill weighs 1.0 grams.The addition of above-mentioned binding agent is 0.2: 1 with the ratio that the described material that mixes adds weight.
The Chinese medicine of the treatment diseases of cardiovascular and cerebrovascular systems of embodiment 5, present embodiment is the Chinese medicine preparation made from each raw material of following weight proportioning, takes by weighing each raw material (kilogram) by following weight proportion:
Calculus Bovis 20 Radix Paeoniae Rubra 25 Herba speranskiae tuberculataes 12
Cornu Bubali powder 15 Indigo Naturaliss 8 Pericarpium Citri Reticulatae Virides 25
Moschus 10 Radix Scrophulariaes 12 Folium Isatidiss 12
Fel Ursi 12 Radix Isatidiss 25 Herba Taraxacis 12
Radix Angelicae Sinensis 10 Picrorhiza scrophulariifloras 12 SHANZHIZI 30
The Radix Rehmanniae 10 Semen Platycladi 25 Borneolum Syntheticums 15
Flos Lonicerae 10 baked polygonum capitatums 25 Periostracum Cicadaes 12
Fructus Forsythiae 12 Endothelium Corneum Gigeriae Galli 25 Radix Aucklandiae 30
Radix Pseudostellariae 20 Fructus Amomis 10 Fructus Amomi Rotunduss 20
Radix Codonopsis 25 Radix Arnebiae (Radix Lithospermi)s 25
Its preparation method is:
Get Moschus earlier, Borneolum Syntheticum, Fel Ursi, described each raw material beyond the Cornu Bubali powder is cleaned with clear water, subsequently above-mentioned each raw material of cleaning is dried, pulverize, be ground into 150 purpose fine powders, with described each fine powder raw material and Fel Ursi, Cornu Bubali powder is prepared burden by above-mentioned weight proportion (kilogram), mix, stir, under 100 ℃～110 ℃ temperature, carry out ripening afterwards, sterilization treatment 10 minutes, the Moschus and the Borneolum Syntheticum (fine-powdered) that add the process sterilization treatment then by above-mentioned weight proportion, add suitable amount of adhesive, mix homogeneously in 5 minutes is made the medicament of required dosage form.Binding agent in the present embodiment is that concentration is the honey aqueous solution of 60% (volume), adds an amount of above-mentioned honey aqueous solution in the material that is mixed toward described each raw material, mix homogeneously in 5 minutes, and the medicament of honeyed pill dosage form is made in molding, and each honeyed pill weighs 1.0 grams.The addition of above-mentioned binding agent is 0.2: 1 with the ratio that the described material that mixes adds weight.
Embodiment 6, Chinese medicine of the present invention also will take by weighing following two kinds of raw materials (kilogram) except that take by weighing each raw material (kilogram) by each raw material weight proportioning described in the embodiment 1:
18 kilograms of Radix Arnebiae (Radix Lithospermi)s, 15 kilograms in Fructus Amomi Rotundus.
Its preparation method is:
Described each raw material of getting earlier beyond the Moschus, Borneolum Syntheticum, Fel Ursi, Cornu Bubali powder is cleaned with clear water, subsequently above-mentioned each raw material of cleaning is dried, pulverized, be ground into 180 purpose fine powders, described each fine powder raw material and Fel Ursi, Cornu Bubali powder are prepared burden, mixed by above-mentioned weight proportion (kilogram), stir, under 100 ℃～110 ℃ temperature, carried out ripening, sterilization treatment 25 minutes afterwards, the Moschus and the Borneolum Syntheticum that add the process sterilization treatment then by above-mentioned weight proportion, add suitable amount of adhesive, mix homogeneously in 5 minutes is made the medicament of required dosage form.Binding agent in the present embodiment is that concentration is the honey aqueous solution of 55% (volume), adds an amount of above-mentioned honey aqueous solution in the material that is mixed toward described each raw material, mix homogeneously in 5 minutes, and the medicament of honeyed pill dosage form is made in molding, and each honeyed pill weighs 1.0 grams.The addition of above-mentioned binding agent is 0.2: 1 with the ratio that the described material that mixes adds weight.
Embodiment 7 Chinese medicines of the present invention have also increased by 10 kilograms of Rhizoma Belamcandae except that taking by weighing each raw material by embodiment 4 described each raw material weight proportioning.Certainly Rhizoma Belamcandae weight be 15 kilograms, 20 kilograms etc. all can, as long as in 10-20 kilogram scope.
In this example, the addition of Rhizoma Belamcandae is 10 kilograms.
Its preparation method is:
Get Moschus earlier, Borneolum Syntheticum, Fel Ursi, described each raw material beyond the Cornu Bubali powder, clean, mix, subsequently above-mentioned each clean raw material is dried, be ground into 120 fine powder, then with (kilogram) by above-mentioned weight proportion claim Fel Ursi, Cornu Bubali powder mixes, stir, obtain elementary mixed material, under 100 ℃～110 ℃ temperature, carry out ripening afterwards, sterilization treatment 15 minutes, the Moschus and the Borneolum Syntheticum (fine-powdered) that add the process sterilization treatment then by above-mentioned weight proportion, add suitable amount of adhesive, mix homogeneously in 5 minutes is made the medicament of required dosage form.Binding agent in the present embodiment is that concentration is the honey aqueous solution of 50% (volume), adds an amount of above-mentioned honey aqueous solution in the material that is mixed toward described each raw material, mix homogeneously in 5 minutes, and the medicament of honeyed pill dosage form is made in molding, and each honeyed pill weighs 1.0 grams.The addition of above-mentioned binding agent is 0.2: 1 with the ratio that the described material that mixes adds weight.
The Chinese medicine of the treatment diseases of cardiovascular and cerebrovascular systems of embodiment 8, present embodiment is the Chinese medicine preparation made from each raw material of following weight proportioning, takes by weighing each raw material (kilogram) by following weight proportion:
Calculus Bovis 2 Radix Paeoniae Rubra 15 Pericarpium Citri Reticulatae Virides 15
Cornu Bubali powder 8 Indigo Naturaliss 10 Folium Isatidiss 12
Moschus 3 Radix Scrophulariaes 15 Herba Taraxacis 20
Fel Ursi 3 Radix Isatidiss 20 SHANZHIZI 25
Radix Angelicae Sinensis 20 Picrorhiza scrophulariifloras 20 Borneolum Syntheticums 12
The Radix Rehmanniae 20 Semen Platycladi 20 Periostracum Cicadaes 15
Flos Lonicerae 15 baked polygonum capitatums 15 Radix Aucklandiae 15
Fructus Forsythiae 15 Endothelium Corneum Gigeriae Galli 15 Radix Arnebiae (Radix Lithospermi)s 15
Radix Pseudostellariae 18 Fructus Amomis 18 Fructus Amomi Rotunduss 18
Radix Codonopsis 20 Herba speranskiae tuberculataes 20 Rhizoma Belamcandae 18
Its preparation method is:
Described each raw material of getting earlier beyond the Moschus, Borneolum Syntheticum, Fel Ursi, Cornu Bubali powder is cleaned with clear water, subsequently above-mentioned each raw material of cleaning is dried, pulverized, be ground into the fine powder of 100 orders-180 order (100 orders, 120 orders, 150 orders, 180 orders etc. all can), be 120 order fine powders herein.Described each fine powder raw material and Fel Ursi, Cornu Bubali powder are prepared burden, mixed by above-mentioned weight proportion (kilogram), stir, under 100 ℃～110 ℃ temperature, carried out ripening, sterilization treatment 20 minutes afterwards, the Moschus and the Borneolum Syntheticum (fine-powdered) that add the process sterilization treatment then by above-mentioned weight proportion (kilogram), add suitable amount of adhesive, mix homogeneously in 5 minutes is made the medicament of required dosage form.The described binding agent of present embodiment is that concentration is the honey aqueous solution of 40% (volume), add an amount of above-mentioned honey aqueous solution in the material that is mixed toward described each raw material, mix homogeneously in 5 minutes, the medicament of honeyed pill dosage form is made in molding, 1.0 kilograms of each honeyed pill, above-mentioned honey aqueous solution addition (kilogram) is 0.1: 1 with the ratio of the weight of material (kilogram) that each raw material is mixed.
The Chinese medicine of the treatment diseases of cardiovascular and cerebrovascular systems of embodiment 9, present embodiment is the Chinese medicine preparation made from each raw material of following weight proportioning, takes by weighing each raw material (kilogram) by following weight proportion:
Calculus Bovis 10 Radix Paeoniae Rubra 22 Pericarpium Citri Reticulatae Virides 20
Cornu Bubali powder 12 Indigo Naturaliss 15 Folium Isatidiss 18
Moschus 8 Radix Scrophulariaes 20 Herba Taraxacis 15
Fel Ursi 8 Radix Isatidiss 15 SHANZHIZI 20
Radix Angelicae Sinensis 15 Picrorhiza scrophulariifloras 15 Borneolum Syntheticums 6
The Radix Rehmanniae 15 Semen Platycladi 15 Periostracum Cicadaes 20
Flos Lonicerae 20 baked polygonum capitatums 20 Radix Aucklandiae 20
Fructus Forsythiae 20 Endothelium Corneum Gigeriae Galli 22 Radix Arnebiae (Radix Lithospermi)s 20
Radix Pseudostellariae 15 Fructus Amomis 12 Fructus Amomi Rotunduss 12
Radix Codonopsis 15 Herba speranskiae tuberculataes 15 Rhizoma Belamcandae 12
Its preparation method is:
Get Moschus earlier, Borneolum Syntheticum, Fel Ursi, described each raw material beyond the Cornu Bubali powder is cleaned with clear water, subsequently above-mentioned each raw material of cleaning is dried, pulverize, be ground into 100 orders-180 purpose fine powder, with described each fine powder raw material and Fel Ursi, Cornu Bubali powder is prepared burden by described weight proportion (kilogram), mix, stir, under 100 ℃～110 ℃ temperature, carry out ripening afterwards, sterilization treatment 25 minutes, the Moschus and the Borneolum Syntheticum (fine-powdered) that add the process sterilization treatment then by above-mentioned weight proportion, add suitable amount of adhesive, mix homogeneously in 5 minutes is made the medicament of required dosage form.Above-mentioned binding agent is that concentration is the ethanol water of 10%-40% (volume), and as 10%, 15%, 20%, 25%, 30%, 35%, 40% etc., binding agent herein is that concentration is 35% ethanol water.Above-mentioned binding agent is joined in the material that is mixed of each raw material, stir, mix homogeneously is made the granule of 20 orders-60 order size, and oven dry incapsulates, and makes said capsule formulation on the pharmaceutics, and each capsule weighs 0.5 gram.The addition of above-mentioned ethanol water (kilogram) is 0.2: 1 with the ratio of the weight of material (kilogram) that each raw material is mixed.
The Chinese medicine of the treatment diseases of cardiovascular and cerebrovascular systems of embodiment 10, present embodiment is the Chinese medicine preparation made from each raw material of following weight proportioning, takes by weighing each raw material (kilogram) by following weight proportion:
Calculus Bovis 6 Radix Paeoniae Rubra 20 Pericarpium Citri Reticulatae Virides 18
Cornu Bubali powder 10 Indigo Naturaliss 12 Folium Isatidiss 16
Moschus 4 Radix Scrophulariaes 18 Herba Taraxacis 16
Fel Ursi 4 Radix Isatidiss 18 SHANZHIZI 22
Radix Angelicae Sinensis 18 Picrorhiza scrophulariifloras 18 Borneolum Syntheticums 8
The Radix Rehmanniae 18 Semen Platycladi 18 Periostracum Cicadaes 18
Flos Lonicerae 16 baked polygonum capitatums 18 Radix Aucklandiae 18
Fructus Forsythiae 18 Endothelium Corneum Gigeriae Galli 20 Radix Arnebiae (Radix Lithospermi)s 18
Radix Pseudostellariae 16 Fructus Amomis 15 Fructus Amomi Rotunduss 15
Radix Codonopsis 18 Herba speranskiae tuberculataes 18 Rhizoma Belamcandae 15
Its preparation method is:
Get Moschus earlier, Borneolum Syntheticum, Fel Ursi, described each raw material beyond the Cornu Bubali powder is cleaned with clear water, then above-mentioned each raw material of cleaning is dried, pulverize, be ground into 180 purpose fine powders, with described each fine powder raw material and Fel Ursi, Cornu Bubali powder is prepared burden by above-mentioned weight proportion (kilogram), mix, stir, obtain elementary mixed material, afterwards it is carried out ripening under 100 ℃～110 ℃ temperature, sterilization treatment 10 minutes, the Moschus and the Borneolum Syntheticum that add the process sterilization treatment then by above-mentioned weight proportion (kilogram), add suitable amount of adhesive, in 5 minutes, mix equal anatomy, make the medicament of required dosage form.The described binder concn of present embodiment is the honey aqueous solution of 70% (volume), add an amount of above-mentioned honey aqueous solution in the material that is mixed toward described each raw material, mix homogeneously in 5 minutes, medicament among the present invention of honeyed pill dosage form is made in molding, each honeyed pill weighs 1.0 grams, and the be mixed ratio of the weight of material (kilogram) that forms of the addition of above-mentioned honey aqueous solution (kilogram) and above-mentioned each raw material is 0.2: 1.
Described Moschus of the various embodiments described above and Fel Ursi are taken from artificial a large amount of Moschus moschiferous and Bears of culturing respectively.
Claims (10)
1, a kind of Chinese medicine for the treatment of diseases of cardiovascular and cerebrovascular systems is characterized in that, it is by mainly containing the medicament that the following weight proportion raw material is made:
Calculus Bovis 1-20 part Radix Codonopsis 15-25 part Fructus Amomi 10-20 part
Cornu Bubali powder 5-15 part Radix Paeoniae Rubra 12-25 part Herba speranskiae tuberculatae 12-25 part
Moschus 1-10 part Indigo Naturalis 8-18 part Pericarpium Citri Reticulatae Viride 12-25 part
Fel Ursi 2-12 part Radix Scrophulariae 12-25 part Folium Isatidis 12-20 part
Radix Angelicae Sinensis 10-25 part Radix Isatidis 12-25 part Herba Taraxaci 12-20 part
Radix Rehmanniae 10-25 part Picrorhiza scrophulariiflora 12-25 part SHANZHIZI 15-30 part
Flos Lonicerae 10-25 part Semen Platycladi 15-25 part Borneolum Syntheticum 6-15 part
Fructus Forsythiae 12-25 part baked polygonum capitatum 15-25 part Periostracum Cicadae 12-25 part
Radix Pseudostellariae 12-20 part Endothelium Corneum Gigeriae Galli 15-25 part Radix Aucklandiae 15-30 part
Above-mentioned umber is a weight portion.
2, the Chinese medicine of treatment diseases of cardiovascular and cerebrovascular systems according to claim 1 is characterized in that, it also contains the following weight proportion raw material:
Radix Arnebiae (Radix Lithospermi) 12-25 part Fructus Amomi Rotundus 10-20 part
3, the Chinese medicine of treatment diseases of cardiovascular and cerebrovascular systems according to claim 1 and 2 is characterized in that, it also contains the following weight proportion raw material: Rhizoma Belamcandae 10-20 part.
4, the Chinese medicine of treatment diseases of cardiovascular and cerebrovascular systems according to claim 3 is characterized in that, the weight proportion of described each raw material is:
Calculus Bovis 2-10 part Radix Paeoniae Rubra 15-22 part Pericarpium Citri Reticulatae Viride 15-20 part
Cornu Bubali powder 8-12 part Indigo Naturalis 10-15 part Folium Isatidis 12-18 part
Moschus 3-8 part Radix Scrophulariae 15-20 part Herba Taraxaci 15-20 part
Fel Ursi 3-8 part Radix Isatidis 15-20 part SHANZHIZI 20-25 part
Radix Angelicae Sinensis 15-20 part Picrorhiza scrophulariiflora 15-20 part Borneolum Syntheticum 6-12 part
Radix Rehmanniae 15-20 part Semen Platycladi 15-20 part Periostracum Cicadae 15-20 part
Flos Lonicerae 15-20 part baked polygonum capitatum 15-20 part Radix Aucklandiae 15-20 part
Fructus Forsythiae 15-20 part Endothelium Corneum Gigeriae Galli 15-22 part Radix Arnebiae (Radix Lithospermi) 15-20 part
Radix Pseudostellariae 15-18 part Fructus Amomi 12-18 part Fructus Amomi Rotundus 12-18 part
Radix Codonopsis 15-20 part Herba speranskiae tuberculatae 15-20 part Rhizoma Belamcandae 12-18 part
5, the Chinese medicine of treatment diseases of cardiovascular and cerebrovascular systems according to claim 4 is characterized in that, the weight proportion of described each raw material is:
18 parts on 20 parts of Pericarpium Citri Reticulatae Virides of 6 parts of Radix Paeoniae Rubra of Calculus Bovis
16 parts of 12 portions of Folium Isatidiss of 10 parts of Indigo Naturaliss of Cornu Bubali powder
16 parts of 18 parts of Herba Taraxacis of 4 portions of Radix Scrophulariaes of Moschus
22 parts of 18 parts of SHANZHIZI of 4 parts of Radix Isatidiss of Fel Ursi
8 parts of 18 parts of Borneolum Syntheticums of 18 parts of Picrorhiza scrophulariifloras of Radix Angelicae Sinensis
18 parts of 18 parts of Periostracum Cicadae of 18 parts of Semen Platycladi of the Radix Rehmanniae
18 parts of 18 parts of Radix Aucklandiae of 16 parts of baked polygonum capitatums of Flos Lonicerae
18 parts of 20 portions of Radix Arnebiae (Radix Lithospermi)s of 18 parts of Endothelium Corneum Gigeriae Galli of Fructus Forsythiae
15 parts in 15 parts of Fructus Amomi Rotunduss of 16 parts of Fructus Amomis of Radix Pseudostellariae
15 parts of 18 parts of Rhizoma Belamcandae of 18 parts of Herba speranskiae tuberculataes of Radix Codonopsis
According to the Chinese medicine of any one described treatment diseases of cardiovascular and cerebrovascular systems in the claim 1 to 5, it is characterized in that 6, described medicament is a said dosage form on any pharmaceutics.
7, the Chinese medicine of treatment diseases of cardiovascular and cerebrovascular systems according to claim 6 is characterized in that, described medicament is said honeyed pill dosage form or a capsule formulation on the pharmaceutics.
8, the preparation method of Chinese medicine of the described treatment diseases of cardiovascular and cerebrovascular systems of claim 6, it is characterized in that, preparation as follows: 1. get Moschus, Borneolum Syntheticum, Fel Ursi, Cornu Bubali powder described each raw material in addition earlier, clean, subsequently above-mentioned each raw material of cleaning is dried, pulverized, it is ground into 100 orders-180 purpose fine powder, above-mentioned each fine powder raw material and described Fel Ursi, Cornu Bubali powder are prepared burden, mixed by described weight proportion, stir, obtain elementary mixed material; Perhaps take by weighing Moschus, Borneolum Syntheticum, Fel Ursi, Cornu Bubali powder described each raw material in addition by described weight proportion earlier, clean, mix, the material that each raw material of cleaning is mixed is dried subsequently, be ground into 100 orders-180 purpose fine powder, then with claim by described weight proportion Fel Ursi, Cornu Bubali powder mix, stir, obtain described elementary mixed material; 2. the above-mentioned elementary mixed material that stirs is carried out ripening, sterilization treatment 10-40 minute under 100 ℃～110 ℃ temperature, the Moschus and the Borneolum Syntheticum that add the process sterilization treatment then by described weight proportion, add suitable amount of adhesive, mix homogeneously in 5 minutes is made the Chinese drugs agentia of required dosage form.
9, the preparation method of Chinese medicine of treatment diseases of cardiovascular and cerebrovascular systems according to claim 8, it is characterized in that, described binding agent is that concentration is the honey aqueous solution of 30%-70% (volume), add an amount of above-mentioned honey aqueous solution in the material that is mixed toward described each raw material, mix homogeneously in 5 minutes, molding make the medicament of honeyed pill dosage form.
10, the preparation method of Chinese medicine of treatment diseases of cardiovascular and cerebrovascular systems according to claim 8, it is characterized in that, described binding agent is that concentration is the ethanol water of 10%-40% (volume), add an amount of described ethanol water in the material that is mixed toward described each raw material, mix homogeneously is made the granule of 20 orders-60 order size, oven dry, incapsulate, make the medicament of said capsule formulation on the pharmaceutics.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101181600B (en) * | 2007-11-20 | 2010-07-21 | 王振才 | Traditional Chinese medicine composition for curing cardiovascular and cerebrovascular diseases |
| CN101301447B (en) * | 2008-04-03 | 2010-10-06 | 乔兴茂 | Chinese medicinal composition for treating epilepsy |
| CN103816280A (en) * | 2014-03-25 | 2014-05-28 | 崔新明 | Traditional Chinese medicine composition for treating myocardial infarction and application of traditional Chinese medicine composition |
| CN103948832A (en) * | 2014-05-29 | 2014-07-30 | 张军 | Traditional Chinese medicine preparation for lowering blood pressure |
-
2002
- 2002-09-29 CN CN 02131349 patent/CN1413653A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101181600B (en) * | 2007-11-20 | 2010-07-21 | 王振才 | Traditional Chinese medicine composition for curing cardiovascular and cerebrovascular diseases |
| CN101301447B (en) * | 2008-04-03 | 2010-10-06 | 乔兴茂 | Chinese medicinal composition for treating epilepsy |
| CN103816280A (en) * | 2014-03-25 | 2014-05-28 | 崔新明 | Traditional Chinese medicine composition for treating myocardial infarction and application of traditional Chinese medicine composition |
| CN103816280B (en) * | 2014-03-25 | 2015-05-13 | 崔新明 | Traditional Chinese medicine composition for treating myocardial infarction and application of traditional Chinese medicine composition |
| CN103948832A (en) * | 2014-05-29 | 2014-07-30 | 张军 | Traditional Chinese medicine preparation for lowering blood pressure |
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