CN1327878C - Prepared Chinese medicine for treating insomnia and preparaton method - Google Patents

Prepared Chinese medicine for treating insomnia and preparaton method Download PDF

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Publication number
CN1327878C
CN1327878C CNB031172253A CN03117225A CN1327878C CN 1327878 C CN1327878 C CN 1327878C CN B031172253 A CNB031172253 A CN B031172253A CN 03117225 A CN03117225 A CN 03117225A CN 1327878 C CN1327878 C CN 1327878C
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angelicae sinensis
radix angelicae
chinese patent
patent medicine
rhizoma anemarrhenae
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CNB031172253A
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CN1519005A (en
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孔农
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Guizhou Runsheng Pharmacy Co ltd
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BENCAOTANG MEDICINE Co Ltd GUIZHOU
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Abstract

The present invention relates to a Chinese patent medicine for treating insomnia and a preparing method thereof. The Chinese patent medicine for treating insomnia is formed by preparing eight raw material medicines, such as spine date seed, Chinese arborvitae kernel, silktree albizzia bark, tuber fleeceflower stem, angelica, cape jasmine fruit, rhizoma anemarrhenae and figwort root, and the raw material medicines are processed and prepared according to certain proportion. The medicines are together used for effectively treating insomnia caused by the deficiency of heart-blood and excessive heart-fire flaming up.

Description

A kind of Chinese patent medicine of Cure for insomnia disease and production method thereof
Technical field: the invention belongs to Chinese patent medicine pharmaceutical technology and new medicine using method, specifically is a kind of Chinese patent medicine and production and Therapeutic Method of Cure for insomnia disease.
Technical background: along with China enters increasing of aged society and operating pressure, blood deficiency, the caused insomnia's problem of flaming up of heart-fire have become a common problem.Existing Chinese medicine and western medicine ubiquity toxic side effect is big, and easily addiction diminishes evil to the central nervous system, influences the metabolic systemic medication reaction of normal organ, makes toxic and side effects such as continuing to increase of dosage.
Seedling medical knowledge opinion thinks that health promptly has " god ", shows that QI and blood fills Sheng." refreshing prosperous then strong, angel is then sick ", simultaneously, " refreshing peace is then slept, god be hard on sleep ".Etiology and pathogenesis actually mostly is vexed and thinks much or weakness due to chronic disease is felt frustrated due to the blood trouble.Because deficiency of vital energy insufficiency of blood, interior heat stagnation is given birth to, and must cause insomnia, refreshing tired, the discomfort of having a dizzy spell.Seedling medical knowledge opinion is thought, if the short-term dysphoria is difficult for falling asleep, and dreaming often and waking easily, no longer sleeping person mostly is into hot warp after waking up, and belongs to calentura; And long-term being difficult for falls asleep, dreaming often and waking easily, and the Mental fatigue person mostly is into cold warp, belongs to cold disease.So above-mentioned all diseases by the principle of " cold febrile disease is controlled, and calentura is cold to be controlled ", should be taken into account treatment by cold and hot medicine when being cold and hot complication.
1, Semen Ziziphi Spinosae, this product are the dry mature seed of Rhamnaceae plant Ziziphi Spinosae ZiziphusjujubaMill.var.spiosa (bunge) Huex H.F.Chou.The property flat, sweet in the mouth is gone into cold warp, the tool nourishing the liver, keeps the heart, mind-easing function.
2, Semen Platycladi, this product are the dry mature kernal of Cupressaceae plant Cacumen Platycladi Platycladus orientalis (L.) Franco.Property is put down, and sweet in the mouth is gone into cold warp, tool tranquilizing by nourishing the heart function.
3, Cortex Albiziae, this product are the dry bark of leguminous plant Herba Albiziae Albiziajulibrissin Durazz..The property flat, sweet in the mouth is gone into cold warp, the tool resolving depression function of calming the nerves.
4, Caulis Polygoni Multiflori, this product are that the dry rattan of polygonum multiflorum thunb Polygonm multiflorumThunb. is cold, and bitter in the mouth, puckery is gone into heat warp, fast warp, and the tool QI invigorating is enriched blood, mind-easing function.
5, Radix Angelicae Sinensis, this product are the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.Sweet in the mouth, suffering, warm in nature, go into cold warp, the tool effect of enriching blood, invigorate blood circulation.
7, the Rhizoma Anemarrhenae, this product are liliaceous plant Rhizoma Anemarrhenae Anemarrhena a sphodeloiDes. dry rhizome.Bitter in the mouth cold in nature is gone into hot warp, the function of tool nourishing YIN to lower pathogenic fire.
8, Radix Scrophulariae, this product are the dry root of goatweed Radix Scrophulariae Scrophularia ningpoensisHemsl..Kucheng, hot warp is gone in cold.Tool YIN nourishing, pathogenic fire reducing, relieving restlessness, function of detoxification.
Summary of the invention: the present invention is according to Miao ethnic group's theory of medicine, propose a kind of by Semen Ziziphi Spinosae, Semen Platycladi, Cortex Albiziae, Caulis Polygoni Multiflori, Radix Angelicae Sinensis, Fructus Gardeniae, the Rhizoma Anemarrhenae, Radix Scrophulariae 8 flavor material medicines are processed by a certain percentage and are produced, and use the foot bath Therapeutic Method, treatment blood deficiency, the caused insomnia's of flaming up of heart-fire Chinese patent medicine.
Component of the present invention (weight ratio) is:
Semen Ziziphi Spinosae: Semen Platycladi: Cortex Albiziae: Caulis Polygoni Multiflori: Radix Angelicae Sinensis: Fructus Gardeniae: the Rhizoma Anemarrhenae: Radix Scrophulariae=(1.5-10): (2.5-10): (1.5-8): (1.5-8): (1.0-8): (1.0 1 5): (1-3): (1-3)
More than eight flavor medical materials, get Radix Angelicae Sinensis and extract volatile oil, the aqueous solution after distillation device is in addition collected; Seven flavors such as medicinal residues and Cortex Albiziae, decoct with water 1~5 time, each 0.5~4 hour, collecting decoction, filter, filtrate is left standstill, and gets supernatant and above-mentioned aqueous solution and merges, and being concentrated into relative density is the clear paste of 1.01~1.40 (25~80 ℃), concentrate, add Radix Angelicae Sinensis volatile oil,, make solid preparation and liquid preparation with different conventional production process.
The all medicines of the present invention are shared, can effectively treat blood deficiency, the caused insomnia of flaming up of heart-fire.Use the foot bath Therapeutic Method, the both acupuncture point administrations that can enrich from the vola, the class medicine of can avoiding again calming the nerves is because of big to the human body toxic and side effects from esophagus administration cause, and easily addiction to central nervous system damage, influences the metabolic systemic medication reaction of normal organ.
The specific embodiment:
Embodiment one, gets Semen Ziziphi Spinosae 250 grams, Semen Platycladi 150 grams, Cortex Albiziae 100 grams, Caulis Polygoni Multiflori 100 grams, Radix Angelicae Sinensis 100 grams, Fructus Gardeniae 100 grams, the Rhizoma Anemarrhenae 100 grams, Radix Scrophulariae 100 grams.More than eight flavor medical materials, get Radix Angelicae Sinensis and extract volatile oil, the aqueous solution after distillation device is in addition collected; Seven flavors such as medicinal residues and Cortex Albiziae decoct with water each 1 hour three times, collecting decoction filters, and filtrate is left standstill, get supernatant and above-mentioned aqueous solution and merge, being concentrated into relative density is the clear paste of 1.1~1.2 (50 ℃), adds chitin 5g, the limit edged stirs evenly, and leaves standstill, and filters, filtrate is concentrated into 950ml, adds Radix Angelicae Sinensis volatile oil, sodium benzoate, regulates pH value to 3.0~5.5 with 20% sodium hydroxide solution, add water to ormal weight, stir evenly, get liquid preparation for external application.
Embodiment two, get Semen Ziziphi Spinosae 500 grams, Semen Platycladi 300 grams, Cortex Albiziae 150 grams, Caulis Polygoni Multiflori 150 grams, Radix Angelicae Sinensis 100 grams, Fructus Gardeniae 120 grams, the Rhizoma Anemarrhenae 200 grams, Radix Scrophulariae 100 grams.More than eight flavor medical materials, get Radix Angelicae Sinensis and extract volatile oil, the aqueous solution after distillation device is in addition collected; Seven flavors such as medicinal residues and Cortex Albiziae decoct with water each 1 hour three times, collecting decoction filters, and filtrate is left standstill, get supernatant and above-mentioned aqueous solution and merge, being concentrated into relative density is the clear paste of 1.1~1.2 (50 ℃), adds chitin 5g, the limit edged stirs evenly, and leaves standstill, and filters, filtrate is concentrated into 200ml, adds adjuvants such as Radix Angelicae Sinensis volatile oil, simple syrup, regulates pH value to 3.0~5.5 with 20% sodium hydroxide solution, add water to ormal weight, stir evenly, promptly get oral liquid.
Embodiment three, get Semen Ziziphi Spinosae 250 grams, Semen Platycladi 150 grams, Cortex Albiziae 100 grams, Caulis Polygoni Multiflori 100 grams, Radix Angelicae Sinensis 100 grams, Fructus Gardeniae 100 grams, the Rhizoma Anemarrhenae 100 grams, Radix Scrophulariae 100 grams.More than eight flavor medical materials, get Radix Angelicae Sinensis and extract volatile oil, the aqueous solution after distillation device is in addition collected; Seven flavors such as medicinal residues and Cortex Albiziae decoct with water three times, and each 1 hour, collecting decoction filtered, filtrate is left standstill, and gets supernatant and above-mentioned aqueous solution and merges, and being concentrated into relative density is the clear paste of 1.1~1.2 (50 ℃), adds adjuvants such as starch, make granule, oven dry, tabletting promptly gets oral tablet.

Claims (11)

1. the Chinese patent medicine of a Cure for insomnia disease is characterized in that it is that composition and effectiveness and the acceptable accessories that Semen Ziziphi Spinosae, Semen Platycladi, Cortex Albiziae, Caulis Polygoni Multiflori, Radix Angelicae Sinensis, Fructus Gardeniae, the Rhizoma Anemarrhenae and the Radix Scrophulariae of 1.5-10: 2.5-10: 1.5-8: 1.5-8: 1-8: 1-5: 1-3: 1-3 made as raw material formed by weight ratio.
2. according to the described Chinese patent medicine of claim 1, wherein be the composition and effectiveness of making as raw material by the Radix Scrophulariae of the Rhizoma Anemarrhenae of the Fructus Gardeniae of the Radix Angelicae Sinensis of the Caulis Polygoni Multiflori of the Cortex Albiziae of the Semen Platycladi of the Semen Ziziphi Spinosae of 250g, 150g, 100g, 100g, 100g, 100g, 100g and 100g.
3. according to the described Chinese patent medicine of claim 1, wherein be the composition and effectiveness of making as raw material by the Radix Scrophulariae of the Rhizoma Anemarrhenae of the Fructus Gardeniae of the Radix Angelicae Sinensis of the Caulis Polygoni Multiflori of the Cortex Albiziae of the Semen Platycladi of the Semen Ziziphi Spinosae of 500g, 300g, 150g, 150g, 100g, 120g, 200g and 100g.
4. according to any one described Chinese patent medicine among claims 1-3, it is characterized in that it is liquid preparation for external application, oral liquid, tablet.
5. method of producing the described Chinese patent medicine of claim 1, it is characterized in that taking by weighing Semen Ziziphi Spinosae that weight ratio is 1.5-10: 2.5-10: 1.5-8: 1.5-8: 1-8: 1-5: 1-3: 1-3, Semen Platycladi, Cortex Albiziae, Caulis Polygoni Multiflori, Radix Angelicae Sinensis, Fructus Gardeniae, the Rhizoma Anemarrhenae, Radix Scrophulariae as raw material, get Radix Angelicae Sinensis and extract volatile oil, the aqueous solution after distillation device is in addition collected; With the Radix Angelicae Sinensis medicinal residues with Semen Ziziphi Spinosae, Semen Platycladi, Cortex Albiziae, Caulis Polygoni Multiflori, Fructus Gardeniae, the Rhizoma Anemarrhenae, Radix Scrophulariae, decoct with water 1-5 time, each 0.5-4 hour, collecting decoction filters, and filtrate is left standstill, getting supernatant and above-mentioned aqueous solution merges, being concentrated into 25-80 ℃ of survey relative density is the clear paste of 1.01-1.40, adds Radix Angelicae Sinensis volatile oil, makes solid preparation or liquid preparation with production technology commonly used.
6. according to the described Chinese patent medicine production method of claim 5, it is characterized in that taking by weighing the Semen Ziziphi Spinosae of 250g, the Semen Platycladi of 150g, the Cortex Albiziae of 100g, the Caulis Polygoni Multiflori of 100g, the Radix Angelicae Sinensis of 100g, the Fructus Gardeniae of 100g, the Rhizoma Anemarrhenae of 100g and the Radix Scrophulariae of 100g, get Radix Angelicae Sinensis and extract volatile oil, the aqueous solution after distillation device is in addition collected; The Radix Angelicae Sinensis medicinal residues with Semen Ziziphi Spinosae, Semen Platycladi, Cortex Albiziae, Caulis Polygoni Multiflori, Fructus Gardeniae, the Rhizoma Anemarrhenae, Radix Scrophulariae, are decocted with water 3 times each 1 hour, collecting decoction filters, and filtrate is left standstill, get supernatant and above-mentioned aqueous solution and merge, being concentrated into 50 ℃ of survey relative densities is the clear paste of 1.1-1.2, adds the 5g chitin, the limit edged stirs evenly, leave standstill, filter, filtrate is concentrated into 950ml, add Radix Angelicae Sinensis volatile oil, make solid preparation or liquid preparation with production technology commonly used.
7. according to the described Chinese patent medicine production method of claim 5, it is characterized in that taking by weighing the Semen Ziziphi Spinosae of 500g, the Semen Platycladi of 300g, the Cortex Albiziae of 150g, the Caulis Polygoni Multiflori of 150g, the Radix Angelicae Sinensis of 100g, the Fructus Gardeniae of 120g, the Rhizoma Anemarrhenae of 200g and the Radix Scrophulariae of 100g, get Radix Angelicae Sinensis and extract volatile oil, the aqueous solution after distillation device is in addition collected; The Radix Angelicae Sinensis medicinal residues with Semen Ziziphi Spinosae, Semen Platycladi, Cortex Albiziae, Caulis Polygoni Multiflori, Fructus Gardeniae, the Rhizoma Anemarrhenae, Radix Scrophulariae, are decocted with water 3 times each 1 hour, collecting decoction filters, and filtrate is left standstill, get supernatant and above-mentioned aqueous solution and merge, being concentrated into 50 ℃ of survey relative densities is the clear paste of 1.1-1.2, adds the 5g chitin, the limit edged stirs evenly, leave standstill, filter, filtrate is concentrated into 200ml, add Radix Angelicae Sinensis volatile oil, make solid preparation or liquid preparation with production technology commonly used.
8. according to the described Chinese patent medicine production method of claim 5, it is characterized in that taking by weighing the Semen Ziziphi Spinosae of 250g, the Semen Platycladi of 150g, the Cortex Albiziae of 100g, the Caulis Polygoni Multiflori of 100g, the Radix Angelicae Sinensis of 100g, the Fructus Gardeniae of 100g, the Rhizoma Anemarrhenae of 100g and the Radix Scrophulariae of 100g, get Radix Angelicae Sinensis and extract volatile oil, the aqueous solution after distillation device is in addition collected; With the Radix Angelicae Sinensis medicinal residues with Semen Ziziphi Spinosae, Semen Platycladi, Cortex Albiziae, Caulis Polygoni Multiflori, Fructus Gardeniae, the Rhizoma Anemarrhenae, Radix Scrophulariae, decoct with water 3 times, each 1 hour, collecting decoction filters, and filtrate is left standstill, getting supernatant and above-mentioned aqueous solution merges, being concentrated into 50 ℃ of survey relative densities is the clear paste of 1.1-1.2, adds Radix Angelicae Sinensis volatile oil, makes solid preparation or liquid preparation with production technology commonly used.
9. according to any one described Chinese patent medicine production method among the claim 5-8, wherein resulting clear paste adds adjuvants such as sodium benzoate, obtains the liquid preparation for external application of different size.
10. according to any one described Chinese patent medicine production method among the claim 5-8, wherein resulting clear paste adds adjuvants such as simple syrup, obtains the oral liquid of different size.
11. according to any one described Chinese patent medicine production method among the claim 5-8, wherein resulting clear paste adds adjuvants such as starch and makes granule, tabletting obtains the tablet of different size.
CNB031172253A 2003-01-21 2003-01-21 Prepared Chinese medicine for treating insomnia and preparaton method Expired - Lifetime CN1327878C (en)

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CN100353855C (en) * 2005-07-10 2007-12-12 蓝金义 Health-care tea for tonifying brain
CN101780159B (en) * 2010-03-08 2011-08-10 韩凤珍 Preparation method of traditional Chinese medicine for treating insomnia with deficiency of both heart-qi and gallbladder-qi
CN102793827B (en) * 2012-08-01 2013-11-06 孟庆立 Preparation method for traditional Chinese medicine used for treatment of blood heat type insomnia
CN104288327A (en) * 2014-10-28 2015-01-21 贵州黄平美娘冲民族服饰有限公司 Bath powder with functions of maintaining beauty and keeping young
CN105125915A (en) * 2015-09-09 2015-12-09 桂林盛兴电子科技有限公司 Traditional Chinese medicine preparation for improving sleep and preparing method thereof

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国家药品监督管理局 国家中成药标准汇编中成药地方标准上升国家标准部分,第内科心系分册卷 2002 *

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