CN1327832A - Exterior-applied ointment for treating dermatitis - Google Patents

Abstract

An exterior-applied ointment for treating dermatitis, urticaria, zoster, eczema, pruritus etc. is prepred from 8 Chinese-medicinal materials including phellodendron bark, menthol, scutellaria root, camphor, etc. Its advantages include high curative effect, low toxic by-effect and no recurrence.

Description

A kind of externally-applied ointment for the treatment of dermatitis

The present invention relates to treat the medicine of dermatitis, is to disclose a kind of externally-applied ointment for the treatment of dermatitis, belongs to traditional Chinese medical science pharmaceutical technology field.

Because the outer excessive factor of evil poison of external pollution and patient's human body disease, a lot of dermatitis pertinacious disease obstinates, outbreak repeatedly, influenced people's orthobiosis, medicines such as " dermatitis curatives " has curative effect preferably to this disease, but owing to contain hormone medicine, have very big zest and toxic and side effects, disease is also very strong to the dependency of medicine.

The present invention discloses a kind of externally-applied ointment for the treatment of dermatitis, has evident in efficacyly, has no side effect the characteristics of non-relapse after healing.

Technical solution of the present invention is as follows: according to based on pathogenesis and the treatment principle of Chinese medicine to dermatitis, with reference to the modern Chinese medicine achievement in research, as follows by the theory of Chinese medical science prescription: (by ratio of weight and the number of copies)

Cortex Phellodendri 4～8, Mentholum 4～8, Radix Scutellariae 4～8, Camphora 4～8, Talcum 2～4,

Oleum Caryophylli 1～3, Oleum Cinnamomi 1～3, Borneolum Syntheticum 1～3.

The preferred weight portion rate:

Cortex Phellodendri 6, Mentholum 6, Radix Scutellariae 6, Camphora 6, Talcum 3, Oleum Caryophylli 2,

Oleum Cinnamomi 2, Borneolum Syntheticum 2.

Processing procedure: get Cortex Phellodendri, Radix Scutellariae, Camphora, Talcum decontamination, be ground into 100～180 order fine powders, add Mentholum, Oleum Caryophylli, Oleum Cinnamomi behind the mix homogeneously and grind to form the Borneolum Syntheticum of fine powder, reconcile into ointment formulation.

Using method: clean the affected part, coating, 2～3 times on the one.

Indication: various dermatitis, anaphylaxis urticaria, herpes zoster, pubic louse, rash skin ulcer, tinea corporis, sexually transmited disease, anal eczema, beriberi, nasal obstruction, skin itching, pudendal pruritus etc. all have significant curative effect.

In this patent, be monarch drug, have nourishing YIN to lower pathogenic fire, damp eliminating heat effect, control the eczema that swells and ache and scratch where it itches with the Cortex Phellodendri, be equipped with the hot wind-heat dissipating of Mentholum, control skin wind heat rubella, Radix Scutellariae clearing up internal heat by using drugs of bitter in taste and cold in nature dampness, control the swollen sore of damp and hot pain, Camphora have one's ideas straightened out ward off dirty, the dehumidifying disinsection efficiency, sweet the trembling with fear of Talcum has heat-clearing toxin-expelling functions, is aided with Oleum Caryophylli, Oleum Cinnamomi, the hot cold expelling of Borneolum Syntheticum, the warming middle-JIAO YANG invigorating, anticorrosion antipruritic, control the chancre carbuncle; Each herbal medicine is auxilliary mutually to be usefulness, bring into play antipruritic, antiinflammatory, analgesia, active, promoting muscle growth functions, enhancing human body activity, and therapeutic effect is obvious.

Good effect of the present invention is: pure Chinese herbal medicine preparation, toxic and side effects is little, treating both the principal and secondary aspects of a disease, evident in efficacy, clinical symptom disappearance is rapid, do not rebound after the healing, be adapted to diseases such as various dermatitis, anaphylaxis urticaria, herpes zoster, pubic louse, rash skin ulcer, tinea corporis, sexually transmited disease, anal eczema, beriberi, nasal obstruction, skin itching, pudendal pruritus.

Further specify good effect of the present invention below in conjunction with clinical:

One, diagnostic criteria

Scratch where it itches: two kinds of branch deficiency and excesss, real person is that wind heat wind and cold or damp and hot poison are evil, and objective temperature skin must not catharsis and cause, and clinical manifestation is local pimple, vesicle, erythema, sepage, is common in contact dermatitis, eczema, seborrheic dermatitis etc.Void person can not store up skin often because of deficiency of YIN-blood, or holds concurrently chivalrous exopathogen and cause, is common in skin pruritus.

Two, case diagnosis standard

Select by clinical manifestation: the whole skin that neurodermatitis, eczema, pubic louse, beriberi, sexually transmitted disease (STD) cause infects, geroderma is scratched where it itches.

Three, administrated method

Clean the affected part, with ointment coating of the present invention, 2～3 times on the one.

Four, curative effect determinate standard:

Cure: a month scytitis disappears after the drug withdrawal, and skin can show normal person.

Effectively: scytitis disappears after the medication, reaches normal level.

Produce effects: scytitis alleviates or transference cure gradually after the medication.

Invalid: inflammation disappears very little or does not disappear after the medication, and clinical symptoms is constant.

Neurodermatitis, herpes zoster medication 10 days were a course of treatment, a general medication obvious curative effects course of treatment, and the person of being in a bad way can cure with 2～3 courses of treatment.

The little person of sexually transmitted disease (STD) skin macule area needs 10～20 days, and heavy person is 30 days.

Beriberi is coated with general 1～2 outward and obviously takes effect, and continues healing in 7～10 days.

1～5 day produce effects of skin itching teenager, the gerontal patient cured in 20～30 days.

Eczema the lighter 7～10 days, 2～3 courses of treatment of heavy person.

Pubic louse recovery from illness in 7～10 days.

Nasal obstruction the lighter took effect the same day, and heavy person cured in 10～20 days.

Five, clinical observation result:

For the ease of the contrast of curative effect degree, the patient is divided into test group and matched group, test group adopts medicine coating of the present invention affected part, every day 2～3 times; Matched group is selected " PIKANGWANG (frost) " ointment for use, by its illustration method treatment.Set up test group and matched group patient medical record by medical requirement, to state of an illness itemized record in the therapeutic process.

Test group is selected 147 examples, 20～40 years old 96 people wherein, and 40～60 years old 51 example, male's 98 examples are set up medical record for test group and matched group on request.All patients make regular check on the treatment situation in therapeutic process, finish the back course of treatment and do to check comprehensively.

147 examples are organized in clinical total effects treatment, clinical cure 68 examples (46.3%), produce effects 42 examples (28.6%), effective 21 examples (14.3%), invalid 16 examples (10.8%), total effective rate 89.2%.Matched group 128 examples, clinical cure 31 examples (24.2%), produce effects 26 examples (20.3%), effective 19 examples (14.8%), invalid 52 examples (40.7%), total effective rate 59.3%.Two groups relatively, and the treatment group significantly is better than matched group.See the following form:

Group	Clinical cure (%)	Produce effects (%)	Effectively (%)	Invalid (%)	Total effective rate (%)
						Treatment group 147	68(46.3)	42(28.6)	21(14.3)	16(10.8)	89.2
Matched group 128	31(24.2)??????	26(20.3)	19(14.8)	52(40.7)	59.3

Clinical trial proves that medicine of the present invention is obvious to the dermatitis effect, and stable lasting, the sterilizing and itch-relieving effect is remarkable, and recovery from illness and total effective rate all are better than matched group.

Case 1

Certain woman, 40 years old, suffer from eczema for many years, clinical symptoms is: local pimple, vesicle, erythema, sepage.Apply medicine of the present invention and cured in 30 days, not recurrence in 3 years so far.

Case 2

Certain man, 52 years old, the other dermatitis of suffering from of shank, area reaches 10cm ², used many kinds of medicines: carbamide ointment, fluocinonide ointments etc. are not all cured, and scratch where it itches and increase the weight of, and the epidermis incrustation has secondary infection.Use medicine of the present invention to take effect the same day, through 20 days treatment, the affected part recovery from illness.

Case 3

Certain woman, 38 years old, suffer from pubic louse more than a year, use medicine of the present invention, Anti-Puritic and insecticidal, took effect the same day, treated 7 days, thoroughly removes pubic louse.

Case 4

Zhao, the man, 48 years old, biped toe beriberi infected and festers seriously, itches pain unbearably.Apply the recovery from illness in 14 days of this medicine, not recurrence in 2 years.

Embodiment

Get Cortex Phellodendri 6kg, Mentholum 6kg, Radix Scutellariae 6kg, Camphora 6kg, Talcum 3kg, Oleum Caryophylli 2kg, Oleum Cinnamomi 2kg, Borneolum Syntheticum 2kg.Get Cortex Phellodendri, Radix Scutellariae, Camphora, Talcum decontamination, be ground into 180 order fine powders, add Mentholum, Oleum Caryophylli, Oleum Cinnamomi behind the mix homogeneously and grind to form the Borneolum Syntheticum of fine powder, reconcile into ointment formulation.

Claims (2)

1, a kind of externally-applied ointment for the treatment of dermatitis, it is characterized in that be by the following raw materials in parts by weight number than the preparation of making:

Cortex Phellodendri 4～8, Mentholum 4～8, Radix Scutellariae 4～8, Camphora 4～8, Talcum 2～4,

Oleum Caryophylli 1～3, Oleum Cinnamomi 1～3, Borneolum Syntheticum 1～3.

2, externally used paste according to claim 1 is characterized in that the preferred weight proportioning of each raw material is:

Cortex Phellodendri 6, Mentholum 6, Radix Scutellariae 6, Camphora 6, Talcum 3, Oleum Caryophylli 2,

Oleum Cinnamomi 2, Borneolum Syntheticum 2.