CN1279959C - Capsule for treating fibroma of mammary gland and preparation technique - Google Patents

Abstract

The present invention relates to a capsule for treating mammary gland fibroma and a preparation process thereof. The present invention provides a purely traditional Chinese medicine for treating mammary gland fibroma diseases. The preparation is prepared by the formula combination of the eight Chinese medicinal plants of cochinchina momordica seed, trichosanthes, honeysuckle flower, etc. The preparation process can be divided into decoction of pig's bile into thick paste m juglandis processing, milling of medicines, mixed manufacture of softwood granulation, drying and filling in sacs. The capsule has the advantages of convenient and canonical preparation process, high utilization rate of effective ingredients, fast therapeutic effect and high curative rate; the ready-prepared medicine treats the mammary gland fibroma by blood circulation stimulation, stasis elimination, heat clearing, bind dissipation, chest loosening, pain removal, swelling dispersing and toxin removal.

Description

Treatment mammary gland fibroma capsule and preparation technology thereof

Affiliated technical field

The present invention treats the mammary gland fibroma capsule and preparation technology belongs to treatment pure Chinese medicine compound medicament of cystic hyperplasia of breast and preparation technology thereof, relates in particular to a kind of oral drugs and preparation technology thereof of pure treatment by Chinese herbs tumprigenicity cystic hyperplasia of breast.

Background technology

Mammary gland fibroma is the common breast benign tumor of young women, claim nodules of the breast again, condition of illness is tuberculosis in the breast, circular as ovum gallinaceum, clear border, medium degree is hard, the surface is more smooth, no adhesion, tenderness is not very, the activity that has that pushes away is felt, generally betide top, breast place, most one-sided generation, with Lump in breast, breast carcinoma, the causes of disease such as cyclomastopathy are identical, how worry too much because of depression, the look setback, expectorant coagulates channels, causing the QI and blood retardance forms, clinical symptoms also all is to occur lump and pain in breast, the traditional treatment medication is also basic identical, oral Chinese patent medicine is used XIAOJIN DAN more, little gold plaque, RUKUAIXIAO, ease pill, eliminating stagnation spirit etc., many with promoting blood circulation to remove obstruction in the collateral with enrich blood in the prescription drugs, soothing the liver, be good for the stomach, the Rhizoma Chuanxiong of strong spleen, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Radix Ginseng, Radix Bupleuri etc. are principal agent, external application plaster auxiliary treatment, but the mammary gland fibroma patient mostly is young women, 60% above patient is below 30 years old, wherein 20-25 year the most sees more, and Lump in breast, breast carcinoma, the hyperplasia of mammary glands patient age mostly is middle aged and aged women, the same cause of disease, because each organ pipe in the young women body, blood vessel, meridians are in grows the vigorous and perfect in shape and function stage, among the maximum the intestines and stomach that bears a heavy burden in the many organ pipes in vivo of QI and blood retardance part that depression is worried too much and the look setback cause, and temporarily being obstructed of digestive system, the protein that the patient is absorbed every day, aminoacid, mineral element far can not satisfy the consumption of the body in youth, very easily cause immunity rapid drawdown and endocrine disturbance, again because of " breast belongs to stomach; the large collatereals of taste all is distributed in the heart ", breast endocrine disturbance head ought be wherein, in case arteria coronaria and microcirculation are obstructed, grow tumor cell, promptly suffer from mammary gland fibroma, be subjected to age differences, should not be with the organ pipe that improves that must use with middle aged and aged women, repair blood vessel and dredging the meridian medicine, should be with fast quick-recovery gastrointestinal function, appetite stimulator, sufficient protein is provided, its acid of ammonia, mineral element, improve immunity rapidly, the coronary artery dilating microcirculation improvement, accelerate to eliminate tumor cell and provide medicine for purpose, but this type of Chinese patent medicine is few on the market, at present because the quickening of people's live and work rhythm, the family burden that young women faces, working environment, the employment state is severe more, body and mind, muscle power, energy, emotion more is subject to setback, and mammary gland fibroma patient crowd also enlarges year by year, the market in urgent need symptomatic drugs.

Summary of the invention

The objective of the invention is: the development scientific formulation, select that YAOJING is few, complementary action is remarkable, oral pure Chinese medicine capsule easily again, make that each Chinese crude drug effective ingredient is integrated in one in the prescription, consumption is few, the curative effect height, after the patient is oral, the fast quick-recovery gastrointestinal function of energy, improve immunity rapidly, improve the endocrine disturbance, directly tumor cell is produced and eliminate curative effect, not only reach depressed liver-energy dispersing and QI regulating, the effect of dissipating phlegm and resolving masses, reach the effect of removing obstruction in the collateral to relieve pain, heat-clearing and toxic substances removing, antibiotic anticancer, the logical stasis of blood of invigorating blood circulation, medicinal powder for relieving pain knot simultaneously, the rapid healing mammary gland fibroma.

In order to realize the foregoing invention purpose, the present invention treats the mammary gland fibroma capsule and technical scheme that preparation technology adopted is: crude drug is made up of 1.8% Semen Momordicae, 15% Fructus Trichosanthis, 20% Flos Lonicerae, 16% Bulbus Fritillariae Thunbergii, 5% semen juglandis, 15% eupolyphaga, 2.2% Scorpio and 25% Fel Sus domestica in the treatment mammary gland fibroma capsule formula, wherein Semen Momordicae is a monarch drug, Fructus Trichosanthis, Flos Lonicerae, Bulbus Fritillariae Thunbergii, semen juglandis are ministerial drug, eupolyphaga, Scorpio are adjuvant drug, and Fel Sus domestica is a messenger drug.The capsular technology of preparation treatment mammary gland fibroma is divided into the Fel Sus domestica decocting to thick ointment, semen juglandis is concocted, many medicine powder process, mix the system soft material granulation, dress capsule five road technologies, earlier Fel Sus domestica being added 4 times of amount clear water decocted 40 minutes, be condensed into the thick paste shape, again semen juglandis is put and propagandized hotly in the iron pan to burnt color, pulverize 60 mesh sieves after taking-up cools and became coarse powder, and with Semen Momordicae, Fructus Trichosanthis, Flos Lonicerae, Bulbus Fritillariae Thunbergii, eupolyphaga, the Scorpio mixing was pulverized 120 mesh sieves and was become fine powder, mix into soft material in the Fel Sus domestica thick paste thoroughly and cross 14 order nylon mesh and make granule adding behind coarse powder and the fine powder mix homogeneously at last, behind the O capsule of packing into after 60 ℃ of oven dry, get patent medicine, oral for the patient.According to Traditional Chinese medical theory, eight flavor prescription medicines integrally combine, monarch drug Semen Momordicae bitter but slightly sweet taste, and sharp large intestine is controlled dysentery infantile malnutrition, newborn disease freshwater mussel poison, detumescence blood stasis removing, granulation promoting except that swollen; Fructus Trichosanthis, Flos Lonicerae, Bulbus Fritillariae Thunbergii, semen juglandis are played removing heat-phlegm, sedation and analgesia, relieving stuffiness of the chest by dispersing aggregation of pathogens altogether in the ministerial drug, invigorating blood circulation disappears bitterly.The effect of subduing swelling and detoxicating and logical profit three warmers blood vessels; Adjuvant drug eupolyphaga, Scorpio sedation and analgesia, activating collaterals and eliminating stagnation, blood circulation and removing stasis; The many medicines of messenger drug Fel Sus domestica rate are gone into the heart and are promoted blood circulation, cold tonifying liver and and resistance, unlikely lattice are refused, the fire of eliminating pathogen in the liver gallbladder will be treated infantile malnutrition tomorrow.The collaborative blood circulation promoting and blood stasis dispelling of many medicines, heat clearing away eliminating stagnation, the chest stuffiness relieving disappear bitterly, subduing swelling and detoxicating, control nodules of the breast altogether, and the curative effect height does not recur, and it is moist smooth that patient's breast portion is reappeared.According to the Chinese medicine modern theory, closed the strong bitterness of brucine tool in the Semen Momordicae, but reflexive ground increases gastric secretion, recovers digestive function; Contain triterpene soap water from washing rice, organic acid, resin and several amino acids in the Fructus Trichosanthis, have coronary artery dilating, microcirculation improvement, anticoagulant and antiulcer, antibiotic, antitumaous effect; Contain organic principles such as chlorogenic acid, isochlorogenic acid, Semen Ginkgo instinct in the Flos Lonicerae, have resisting pathogenic microbes, antitoxin, antiinflammatory, refrigeration function and improve immunity and anti-cancer function; Contain peimine and peiminine in the Bulbus Fritillariae Thunbergii, have antitussive, blood pressure lowering, increase coronary flow and strengthen the function that small intestinal shrinks; Semen juglandis contains rich in protein and multiple free essential amino, and has extremely strong anti-cancer function; Contain 17 seed amino acids and Eupolyphaga Seu Steleophaga total alkaloids in the eupolyphaga, have blood vessel dilating, anti-blood and the accent fat liver-protecting function of doubting; Contain scorpion venom and several amino acids in the Scorpio, have analgesia, suppress thrombosis and anti-tumor function.Above-mentioned Chinese medicine ingredients is by analgesia, antitussive, increase gastric secretion, strengthening small intestinal shrinks, nutrition is provided, coronary artery dilating, microcirculation improvement, antitoxin, antiinflammatory, analgesic, transfer fat, hepatoprotective, improve patient body immunity and anti-cancer ability, can be effectively fast quick-recovery patient gastrointestinal function, appetite stimulator, sufficient protein is provided in the donor, aminoacid, mineral element, improve body immunity rapidly, accelerate mammary gland fibroma affected part blood stasis and recover unimpeded, inflammation disappears, pain is eliminated, and under the cytotoxicity of plurality of active ingredients, by sparse tumor cell, shrink, kytoplasm elongates and cavity and cell blebbing phenomenon occur in cell, the mammary gland fibroma patient tumors is disappeared, get well.

The invention has the beneficial effects as follows: the capsular prescription of treatment mammary gland fibroma is updated in long-term prescription is used, select for use the prescription YAOJING few, the compatibility science, have complementary functions, play spleen invigorating stomach strengthening, blood circulation promoting and blood stasis dispelling, heat clearing away eliminating stagnation, subduing swelling and detoxicating, sedation and analgesia effect altogether, treatment mammary gland fibroma capsule taking convenience, curative effect is outstanding, prepare simultaneously easy, technical matters standard, utilization rate of active components height.

Through the observation of curative effect of in January, 2003-2004 year prescription application in October, the patient takes medicine 2 every day, and each 3, and at the treatment mammary gland fibroma plaster (applying for a patent on the same day) that the affected part external application is developed, exchanged cards containing all personal details and become sworn brothers once in per 3 days.Criterion of therapeutical effect: 1. recovery from illness: transference cure, lump disappears.2. produce effects: symptom disappears substantially, and sign is clearly better, and lump dwindles more than 2/3.3. effective: symptom has improvement, and lump dwindles more than 1/2.4. invalid: the equal no change of symptom and sign.Treat 136 routine mammary gland fibroma patients altogether, 95 examples of fully recovering, produce effects 23 examples, effective 11 examples, invalid 7 examples, total effective rate 94.85%.

Specific embodiments:

1, best effectively formula ratio, degree such as following table of each prescription in the treatment mammary gland fibroma capsule:

The Chinese crude drug title	Semen Momordicae	Fructus Trichosanthis	Flos Lonicerae	Bulbus Fritillariae Thunbergii	Semen juglandis	Eupolyphaga	Scorpio	Fel Sus domestica	Add up to
										Formula ratio (gram)	18	150	200	160	50	150	22	250	1000
Content (%)	1.8	15.0	20.0	16.0	5.0	15.0	2.2	25.0	100

2, treatment mammary gland fibroma capsules preparation technique:

1. select the big porker gall bladder for use, it is standby to measure Fel Sus domestica by prescription; And it is standby to get all the other Chinese crude drug well sifted weighings by existing prepared slices of Chinese crude drugs standard.

2. Fel Sus domestica is added 4 times of water gaging slow fires decoctions and be condensed into the thick paste shape in 40 minutes.

3. semen juglandis is put and propagandized hotly in the iron pan, pulverized 60 mesh sieves after taking-up cools and become coarse powder to burnt color.

4. all the other six kinds of tcm and herbal slices are mixed and pulverized 120 mesh sieves and become fine powder, and with semen juglandis coarse powder mixing.

5. after mixing medicated powder being put into thick paste and mixed soft material, cross 14 order nylon mesh and make granule, behind the O capsule of packing into after 60 ℃ of oven dry patent medicine.

3, treatment mammary gland fibroma capsule instructions of taking and consumption:

Oral for the patient, the twice-daily of being grown up, each 4-6 grain.The careful clothes of Deficiency and coldness of spleen and stomach person.

Claims (2)

1, a kind of treatment mammary gland fibroma capsule is characterized in that: crude drug is made up of 1.8% Semen Momordicae, 15% Fructus Trichosanthis, 20% Flos Lonicerae, 16% Bulbus Fritillariae Thunbergii, 5% semen juglandis, 15%  worm, 2.2% Scorpio and 25% Fel Sus domestica in the prescription.

2, treat the capsular preparation technology of mammary gland fibroma according to claim 1, it is characterized in that: earlier Fel Sus domestica is added 4 times of amount clear water and decocted 40 minutes, be condensed into the thick paste shape, again semen juglandis is put and propagandized hotly in the iron pan to burnt color, pulverize 60 mesh sieves after taking-up cools and became coarse powder, and Semen Momordicae, Fructus Trichosanthis, Flos Lonicerae, Bulbus Fritillariae Thunbergii,  worm, Scorpio mixed pulverized 120 and sieve into fine powder, mix into soft material in the Fel Sus domestica thick paste thoroughly and cross 14 order nylon mesh and make granule adding behind coarse powder and the fine powder medicine mix homogeneously at last, behind No. 0 capsule of packing into after 60 ℃ of oven dry patent medicine.