CN1273121A

CN1273121A - Process for preparing medicine to cure amenorrhoea

Info

Publication number: CN1273121A
Application number: CN 99111778
Authority: CN
Inventors: 李健华
Original assignee: Individual
Current assignee: Individual
Priority date: 1999-08-13
Filing date: 1999-08-13
Publication date: 2000-11-15

Abstract

A medicine for treating Qi and blood stasis type amenorrhoea is prepared from 13 Chinese medicinal materials including rhubarb, rehmannia root, peach kernel, almand kernel, red peony root, etc. as raw materials through multi-procedures of decoction and extraction. Its advantages include high curative rate and safety, no any by-effect, no sequela, low dosage and low cost.

Description

A kind of preparation method for the treatment of the medicine of amenorrhea

Project of the present invention is a kind of medicine.Relate generally to a kind of pure Chinese medicinal preparation that the amenorrhea disease has significant curative effect for the treatment of.Amenorrhea is gynecological's common disease, frequently-occurring disease, etiology and pathogenesis complexity clinically.Motherland's medical science is thought: the main cause of amenorrhea be because dash to appoint and visceral dysfunction due to.Deficiency and excess two classes are arranged, and particularly real person mostly is stagnation of QI knot and stagnates, and sering is blocked, and blood stasis with constipation makes the menses must not be descending.The patient occurs: menolipsis, greenish complexion are dim, spirit depressing, irritability, hypochondriac pain uncomfortable in chest, little abdominal distention are painful, tongue has purple point, stringy pulse.At present the treatment of primary disease is gone back the patent medicine of neither one good effect, taking convenience.The western medicine side effect is many, and the very difficult Qin imitates.According to theory of Chinese medical science: follow with blood circulation promoting competent silt, assistant Therapeutic Principle with regulating QI, dialectical plus-minus.

Above purpose is realized by following technology.Adopt: Radix Et Rhizoma Rhei, the Radix Rehmanniae, Semen Persicae, Semen Armeniacae Amarum, Radix Paeoniae Rubra, Radix Scutellariae, forging Resina Toxicodendri, Radix Glycyrrhizae, Tabanus, Hirudo, eupolyphaga, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi etc. are prepared from our promoting blood circulation to restore menstrual flow, removing blood stasis repercussive, Shu Yu circulation of qi promoting, heat-clearing and toxic substances removing.Mainly solve with the caused amenorrhea of qi depression to blood stasis, clinical practice and show that cure rate reaches 89%, effective percentage 98%.

At the medium-term and long-term Radix Et Rhizoma Rhei of using of China traditional medicine, confirmation can stasis removing, purging fire and cooling blood, blood circulation promoting and blood stasis dispelling, promoting the function of the gallbladder to alleviate jaundice.The Radix Rehmanniae: clearing away heat and cooling blood, Yin and detoxification, arresting bleeding and miscarriage prevention; Forge Resina Toxicodendri: broken disease is stimulated the menstrual flow, blood stasis removing dampness, eliminating fire and detoxication; Semen Persicae: removing blood stasis; Moisturize laxation; Radix Scutellariae: heat clearing and damp drying, eliminating fire and detoxication, arresting bleeding and miscarriage prevention; Forge Resina Toxicodendri: broken disease is stimulated the menstrual flow, the blood stasis removing parasite killing; Radix Glycyrrhizae: invigorating the spleen and replenishing QI, coordinating the actions of various ingredients in a prescription, heat-clearing and toxic substances removing; Radix Paeoniae Rubra: the removing heat from blood stasis of blood alive, dispersing swelling and dissipating binds; Tabanus: removing blood stasis eliminating mass; Hirudo: removing blood stasis, the eliminating mass of stimulating the menstrual flow; Eupolyphaga: removing blood stasis loose disease, the continuous damage of stimulating the menstrual flow; Pericarpium Citri Reticulatae Viride: depressed liver-energy dispersing and QI regulating stomach function regulating removing food stagnancy; Rhizoma Cyperi: the resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving.

Up to now: only be used for clinical as decoct, its flavour of a drug bitterness, the stench dose of gas is many, very inconvenient, and drug effect is slow, active ingredient can not make full use of, and the present invention is mainly with above several drugs, through concocting, meticulous extraction processing, organically be combined together, make capsule, make the useful composition of people's body and mind used widely and see accompanying drawing.

Accompanying drawing is made flow chart for medicine of the present invention, in conjunction with figure, preparation method of the present invention is described below:

Prescription: (every part by former medicine weight percent calculating)

Tabanus 4%, Hirudo 6%, Radix Et Rhizoma Rhei 20%, forge Resina Toxicodendri 2%, eupolyphaga 2%, Radix Scutellariae 4%, Semen Armeniacae Amarum 8%, Semen Persicae 8%, Radix Glycyrrhizae 6%, Radix Paeoniae Rubra 8%, Rhizoma Cyperi 6%, Pericarpium Citri Reticulatae Viride 6%, the Radix Rehmanniae 20%, dextrin is an amount of, 80% ethanol is an amount of.

The preparation method of this medicine (by the weight percent of prescription)

1. pulverize, finish grind after getting high-quality, Hirudo, Tabanus, forging Resina Toxicodendri, eupolyphaga, the roguing process of preparing Chinese medicine, get thin medicated powder A

2. use chemical method, extract Radix Scutellariae, effective ingredient respectively, get baicalin crude product B mother solution C, Radix Et Rhizoma Rhei powder E

3. get the high-quality Radix Rehmanniae, Semen Persicae, Semen Armeniacae Amarum, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi, Radix Glycyrrhizae roguing, by the prescription degree, decoct with water, get decocting liquid (G), merge C then, G, concentrate, spray dried, add A, B, E extract and dextrin again and granulate, the ethanol with 80% is moistening in right amount, dry, check, branch is promptly encapsulated.

Claims

1, a kind of preparation method for the treatment of the medicine of amenorrhea.It is characterized in that preparing raw material is: (calculating of precentagewise weight) Tabanus 110 restrains, Hirudo 150 restrains, Radix Et Rhizoma Rhei 500 restrains, forging Resina Toxicodendri 50 restrains, eupolyphaga 50 restrains, Radix Scutellariae 100 restrains, Semen Armeniacae Amarum 200 restrains, Semen Persicae 200 restrains, Radix Glycyrrhizae 150 restrains, Radix Paeoniae Rubra 200 restrains, Rhizoma Cyperi 150 restrains, Pericarpium Citri Reticulatae Viride 150 restrains, the Radix Rehmanniae 500 restrains, an amount of 80% ethanol of dextrin is an amount of.Through the capsule of concocting, purifying, granulate, make.The medicine active ingredient makes full use of, and dose is convenient less, has avoided the stench undesirable element of the bitter gas of former flavour of a drug, and instant effect, cure rate height are this area original creation parts.

2, the present invention is further described with following example for its feature.

1. get high-quality Tabanus 100G, Hirudo 150G, eupolyphaga 50G, forge Resina Toxicodendri 50G roguing, the process of preparing Chinese medicine, pulverize, finish grind thin medicated powder A300G

2. a gets Radix Scutellariae 100G and adds 12 times of amount boiling water and decocted 1 hour, adds 8 times of water gagings again and decocts 30 minutes decocting liquids and filter while hot, transfers PH1-2,80 ° of insulations 30 minutes with HCL, and the leaching precipitate is obtained baicalin crude product B5G mother solution C in 60 ° of oven dry

B: get Radix Et Rhizoma Rhei 500G pulverize, add 12 times of water loggings bubbles 2-3 hour filter below 50 ℃ concentrating under reduced pressure dry extract powder E.

3. get the high-quality Radix Rehmanniae 500 gram Semen Persicaes 200 grams, Semen Armeniacae Amarum 200 grams, Radix Paeoniae Rubra 200 grams, Pericarpium Citri Reticulatae Viride 150 grams, Radix Glycyrrhizae 150 grams, Rhizoma Cyperi 150 grams, roguing is concocted, is added 15 times in water, soaks post-heating decoction in 1 hour 1.5 hours, extracting juice, medicinal residues add 12 times of water gagings again and fried in shallow oil 1 hour, extracting juice, two liquid merge, and get decocting liquid G and merge C, G then, are mixed, carry out coarse filtration and fine straining with filter press.Reuse spray drying method for preparation extract powder.

Extract powder add the thin medicated powder A of baicalin crude product B, extractum rhei powder E, simultaneously add dextrin be mixed in right amount, with an amount of moistening granulation of 80% ethanol, drying, check, packing finished product.