CN1231894A - Antidiarrheal suppository - Google Patents
Antidiarrheal suppository Download PDFInfo
- Publication number
- CN1231894A CN1231894A CN 98113507 CN98113507A CN1231894A CN 1231894 A CN1231894 A CN 1231894A CN 98113507 CN98113507 CN 98113507 CN 98113507 A CN98113507 A CN 98113507A CN 1231894 A CN1231894 A CN 1231894A
- Authority
- CN
- China
- Prior art keywords
- suppository
- antidiarrheal
- probanthine
- berberine
- prednisone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
A constipating suppository for treating diarrhea with special curative effect contains probanthine, berberine, furaxone, prednisone and chlorpheniramine.
Description
The invention belongs to pharmaceutical, be specifically related to a kind of all kinds of diarrheal suppositorys that are used for the treatment of.
Diarrhoea is common clinical, frequently-occurring disease.Using at present the diarrhea medicine has several forms such as costive, astringent, adsorbent, antibiotics, microbial ecological agent, adopts modes such as oral, intravenous drip, intramuscular injection, coloclysis.Compare with aforesaid way, suppository has following characteristics: the destruction that (1) medicine is not subjected to gastrointestinal PH or enzyme, and minimizing is to the stimulation of stomach; (2) medicine absorbs from rectum, the destruction that is subjected to the liver first-pass effect in the time of can avoiding oral; Can alleviate toxicity or pair effect of medicine again to liver; (3) swallow or fear patient or the child who has an injection, convenient drug administration can not or being reluctant.
The present invention in conjunction with the various clinical manifestations of diarrheal, has proposed a kind of have antiinflammatory, harmonizing intestine-stomach, astringing intestine to stop diarrhea pain relieving, to the specific antidiarrheal suppository of all kinds of diarrhoea, as a kind of effective Therapeutic Method for the treatment of diarrhoeal diseases clinically according to the These characteristics of suppository.
The present invention selects several common drugs for use, through the science compatibility, is used for treating various types of diarrhoea.Prescription of the present invention is formed and content (every bolt content) is: probanthine 15-30mg, berberine 200-400mg, furazolidone 200-400mg, prednisone 7.5-15mg, chlorphenamine 4-8mg.Above-mentioned raw materials is utilized the processing of conventional preparation suppository method promptly.
If the antidiarrheal inspection that the preparation child uses only needs to get final product with minimum content in this prescription.
Usage and consumption: each one piece, anus plug, every day three times.
Contraindication: anal fissure, anal fistula, hemorrhoid, colonic ulcer, polyp of colon, colonorrhagia etc.
This product is used observation through Daye City, Hubei Province two hospital outpatients and thousand patients in hospital, and total effective efficiency 95% is organized in treatment, and wherein produce effects 72%, and effective 23%, invalid 5%; The oral norfloxacin of matched group, lactasinum, sulphaguanidine etc., total effective rate 73% is learned by statistics and is handled, and between two groups of total effective rates significant difference (X is arranged
2=3.86,0.01＜P＜0.05), the average natural law of treatment group antidiarrheal is 2.25+-0.76, matched group 3.71+-1.5, and T=24.27 also has significant differences between P＜0.01, two group.Illustrate that treatment group curative effect is apparently higher than matched group.
That this product has is significantly antibiotic, antiinflammatory, antiallergic, analgesia, adjustment gastrointestinal motility function, astringent effect, human body is not had any poison pay effect; Medication just can make stomachache significantly alleviate in two days, and times of defecation reduces, and bloody purulent stool stops.Stool can be shaped or recover normal in general 7 days, adhered to a medication 1-2 course of treatment, and most humans can obtain healing.This therapy is easy to use, neither need spend a lot of medical care expensess to carry out intravenous drip, does not need oral medication again, and is easy to carry, cheap, suitable to vein and oral administration difficulty person especially.
Embodiments of the invention are described in detail in detail below:
Embodiment 1: is example to prepare 10 children with suppository, gets liquid Paraffin 5g, oleum theobromatis 2g heat fused in water-bath, get the 0.15g probanthine then approximately, 2g berberine, 2g furazolidone, 0.75g prednisone, 0.04g chlorphenamine grind into powder and make it to be scattered in equably in the above-mentioned substrate, and then impouring scribbles in the bolt mould of lubricant and is degree to overflowing die orifice slightly, cooling, wait solidify fully after, prune with cutter and to overflow part, open model, release suppository, dry, packing promptly.
Embodiment 2: is example to prepare 100 adults with suppository: get liquid Paraffin 55g, oleum theobromatis 20g heat fused in water-bath is got the 3g probanthine then approximately, the 40g berberine, 40g furazolidone, 1.5g prednisone, 0.8g chlorphenamine grinds into powder and makes it to be scattered in equably in the above-mentioned substrate, and then impouring scribbles in the bolt mould of lubricant and is degree, cooling to overflowing die orifice slightly, wait solidify fully after, prune with cutter and to overflow part, open model, release suppository, dry, packing promptly.
Claims (1)
- A kind of antidiarrheal suppository is characterized in that every bolt contains probanthine 15-30mg, berberine 200-400mg, furazolidone 200-400mg, prednisone 7.5-15mg, chlorphenamine 4-8mg.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 98113507 CN1231894A (en) | 1998-04-14 | 1998-04-14 | Antidiarrheal suppository |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 98113507 CN1231894A (en) | 1998-04-14 | 1998-04-14 | Antidiarrheal suppository |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1231894A true CN1231894A (en) | 1999-10-20 |
Family
ID=5223227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 98113507 Pending CN1231894A (en) | 1998-04-14 | 1998-04-14 | Antidiarrheal suppository |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1231894A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009061587A1 (en) * | 2007-11-09 | 2009-05-14 | Novartis Ag | Corticosteroids to treat epothilone or epothilone derivative induced diarrhea |
-
1998
- 1998-04-14 CN CN 98113507 patent/CN1231894A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009061587A1 (en) * | 2007-11-09 | 2009-05-14 | Novartis Ag | Corticosteroids to treat epothilone or epothilone derivative induced diarrhea |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6217880B1 (en) | Medicament for treating recurrent ulcer of mouth and behcet's syndrome | |
| CN100389802C (en) | Medicine for treating and preventing chronic obstractive pneumonia | |
| CN101703525A (en) | Externally applied medicament for treating oral diseases and preparation method thereof | |
| CN1284585C (en) | Medicine for treating acute and chronic pharyogolaryngitis, recurring oral cavity sore and its preparation method | |
| CN1231894A (en) | Antidiarrheal suppository | |
| CN1318378A (en) | Heat syndrome treating Chinese medicine | |
| CN109966442B (en) | Oral and external traditional Chinese medicine composition for treating ulcerative colitis and preparation method thereof | |
| CN1075386C (en) | Method for producing Anruneixiao medicinal liquid | |
| CN1081374A (en) | The Radix Pseudostellariae treatment of cough and asthma | |
| CN1061538C (en) | Chinese medicine for stomach diseases | |
| CN101129601A (en) | Fructus forsythiae beverage for toothache | |
| CN1092330A (en) | Medical fomentation bag for stop pain | |
| CN111228367A (en) | Traditional Chinese medicine external lotion for treating infantile anaphylactoid purpura and preparation method thereof | |
| CN103933274A (en) | Traditional Chinese medicine preparation for treating periodontitis | |
| CN106266405A (en) | A kind of medicine treating flatulence | |
| CN1088378C (en) | Oral Chinese medicine liquid for treating chronic superficial gastritis and its preparation | |
| CN1255174C (en) | Power of pasting on umbilicus for treating dianhea and abdominal pain of infants | |
| CN1064535C (en) | Medicinal powder for treatment of chronic ulcerative colitis | |
| CN101933743A (en) | Traditional Chinese medical health pillow | |
| CN102319290B (en) | Medicament for preventing cancer cells from proliferating to lungs after radiation treatment of nasopharyngeal darcinoma | |
| CN1229651A (en) | Haemorrhoids powder | |
| CN101632762A (en) | Traditional Chinese medicine ointment for treating child aphtha | |
| CN105663959A (en) | Traditional Chinese medicine preparation for nursing patient suffering from toothache and preparation method | |
| CN1112204C (en) | Traditional Chinese powder medicine for treating cough and preparation process thereof | |
| CN1052906C (en) | External application medicine for treating toothache due to saprodontia |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |