CN1207563C - 生物传感器 - Google Patents
生物传感器 Download PDFInfo
- Publication number
- CN1207563C CN1207563C CNB028018044A CN02801804A CN1207563C CN 1207563 C CN1207563 C CN 1207563C CN B028018044 A CNB028018044 A CN B028018044A CN 02801804 A CN02801804 A CN 02801804A CN 1207563 C CN1207563 C CN 1207563C
- Authority
- CN
- China
- Prior art keywords
- aforementioned
- filtrator
- liquid sample
- biology sensor
- feed path
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Description
Claims (8)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001152868A JP4213361B2 (ja) | 2001-05-22 | 2001-05-22 | バイオセンサ |
JP152868/2001 | 2001-05-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1463360A CN1463360A (zh) | 2003-12-24 |
CN1207563C true CN1207563C (zh) | 2005-06-22 |
Family
ID=18997478
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB028018044A Expired - Fee Related CN1207563C (zh) | 2001-05-22 | 2002-05-17 | 生物传感器 |
Country Status (5)
Country | Link |
---|---|
US (2) | US6706232B2 (zh) |
EP (1) | EP1318396B1 (zh) |
JP (1) | JP4213361B2 (zh) |
CN (1) | CN1207563C (zh) |
WO (1) | WO2002095385A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103424564A (zh) * | 2012-05-18 | 2013-12-04 | 爱科来株式会社 | 生物传感器 |
Families Citing this family (88)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6036924A (en) | 1997-12-04 | 2000-03-14 | Hewlett-Packard Company | Cassette of lancet cartridges for sampling blood |
US6391005B1 (en) | 1998-03-30 | 2002-05-21 | Agilent Technologies, Inc. | Apparatus and method for penetration with shaft having a sensor for sensing penetration depth |
US20050103624A1 (en) | 1999-10-04 | 2005-05-19 | Bhullar Raghbir S. | Biosensor and method of making |
US8641644B2 (en) | 2000-11-21 | 2014-02-04 | Sanofi-Aventis Deutschland Gmbh | Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means |
JP4183902B2 (ja) * | 2000-12-27 | 2008-11-19 | 松下電器産業株式会社 | バイオセンサ |
US7981056B2 (en) | 2002-04-19 | 2011-07-19 | Pelikan Technologies, Inc. | Methods and apparatus for lancet actuation |
US7344507B2 (en) | 2002-04-19 | 2008-03-18 | Pelikan Technologies, Inc. | Method and apparatus for lancet actuation |
WO2002100254A2 (en) | 2001-06-12 | 2002-12-19 | Pelikan Technologies, Inc. | Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge |
US7682318B2 (en) | 2001-06-12 | 2010-03-23 | Pelikan Technologies, Inc. | Blood sampling apparatus and method |
DE60239132D1 (de) | 2001-06-12 | 2011-03-24 | Pelikan Technologies Inc | Gerät zur erhöhung der erfolgsrate im hinblick auf die durch einen fingerstich erhaltene blutausbeute |
US7041068B2 (en) | 2001-06-12 | 2006-05-09 | Pelikan Technologies, Inc. | Sampling module device and method |
AU2002315177A1 (en) | 2001-06-12 | 2002-12-23 | Pelikan Technologies, Inc. | Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties |
JP4149911B2 (ja) | 2001-06-12 | 2008-09-17 | ペリカン テクノロジーズ インコーポレイテッド | 電気式ランセットアクチュエータ |
US9795747B2 (en) | 2010-06-02 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Methods and apparatus for lancet actuation |
US9427532B2 (en) | 2001-06-12 | 2016-08-30 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US9226699B2 (en) | 2002-04-19 | 2016-01-05 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling module with a continuous compression tissue interface surface |
US8337419B2 (en) | 2002-04-19 | 2012-12-25 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
EP1445605A4 (en) | 2001-11-14 | 2005-01-12 | Matsushita Electric Ind Co Ltd | BIOSENSOR |
EP1452857A4 (en) | 2001-11-14 | 2006-05-24 | Matsushita Electric Ind Co Ltd | BIOSENSOR |
CN100339702C (zh) * | 2002-03-01 | 2007-09-26 | 松下电器产业株式会社 | 生物传感器 |
US7371247B2 (en) | 2002-04-19 | 2008-05-13 | Pelikan Technologies, Inc | Method and apparatus for penetrating tissue |
US8360992B2 (en) | 2002-04-19 | 2013-01-29 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7491178B2 (en) | 2002-04-19 | 2009-02-17 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8221334B2 (en) | 2002-04-19 | 2012-07-17 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7547287B2 (en) | 2002-04-19 | 2009-06-16 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7331931B2 (en) | 2002-04-19 | 2008-02-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7909778B2 (en) * | 2002-04-19 | 2011-03-22 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8372016B2 (en) | 2002-04-19 | 2013-02-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for body fluid sampling and analyte sensing |
US7901362B2 (en) | 2002-04-19 | 2011-03-08 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7713214B2 (en) | 2002-04-19 | 2010-05-11 | Pelikan Technologies, Inc. | Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing |
US7717863B2 (en) | 2002-04-19 | 2010-05-18 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US9248267B2 (en) | 2002-04-19 | 2016-02-02 | Sanofi-Aventis Deustchland Gmbh | Tissue penetration device |
US8267870B2 (en) | 2002-04-19 | 2012-09-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for body fluid sampling with hybrid actuation |
US8784335B2 (en) | 2002-04-19 | 2014-07-22 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling device with a capacitive sensor |
US7648468B2 (en) | 2002-04-19 | 2010-01-19 | Pelikon Technologies, Inc. | Method and apparatus for penetrating tissue |
US7674232B2 (en) | 2002-04-19 | 2010-03-09 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US9795334B2 (en) | 2002-04-19 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7976476B2 (en) | 2002-04-19 | 2011-07-12 | Pelikan Technologies, Inc. | Device and method for variable speed lancet |
US7232451B2 (en) | 2002-04-19 | 2007-06-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7291117B2 (en) | 2002-04-19 | 2007-11-06 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7229458B2 (en) | 2002-04-19 | 2007-06-12 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8579831B2 (en) | 2002-04-19 | 2013-11-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US9314194B2 (en) | 2002-04-19 | 2016-04-19 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US7297122B2 (en) | 2002-04-19 | 2007-11-20 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8702624B2 (en) | 2006-09-29 | 2014-04-22 | Sanofi-Aventis Deutschland Gmbh | Analyte measurement device with a single shot actuator |
US7892183B2 (en) | 2002-04-19 | 2011-02-22 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
US7265881B2 (en) * | 2002-12-20 | 2007-09-04 | Hewlett-Packard Development Company, L.P. | Method and apparatus for measuring assembly and alignment errors in sensor assemblies |
US8574895B2 (en) | 2002-12-30 | 2013-11-05 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus using optical techniques to measure analyte levels |
US7550290B2 (en) | 2003-05-15 | 2009-06-23 | Panasonic Corporation | Sensor |
EP1628567B1 (en) | 2003-05-30 | 2010-08-04 | Pelikan Technologies Inc. | Method and apparatus for fluid injection |
US7850621B2 (en) | 2003-06-06 | 2010-12-14 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
WO2006001797A1 (en) | 2004-06-14 | 2006-01-05 | Pelikan Technologies, Inc. | Low pain penetrating |
US7718439B2 (en) | 2003-06-20 | 2010-05-18 | Roche Diagnostics Operations, Inc. | System and method for coding information on a biosensor test strip |
US8148164B2 (en) | 2003-06-20 | 2012-04-03 | Roche Diagnostics Operations, Inc. | System and method for determining the concentration of an analyte in a sample fluid |
US7452457B2 (en) | 2003-06-20 | 2008-11-18 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using dose sufficiency electrodes |
US7645421B2 (en) | 2003-06-20 | 2010-01-12 | Roche Diagnostics Operations, Inc. | System and method for coding information on a biosensor test strip |
US7645373B2 (en) | 2003-06-20 | 2010-01-12 | Roche Diagnostic Operations, Inc. | System and method for coding information on a biosensor test strip |
US8071030B2 (en) | 2003-06-20 | 2011-12-06 | Roche Diagnostics Operations, Inc. | Test strip with flared sample receiving chamber |
US8058077B2 (en) | 2003-06-20 | 2011-11-15 | Roche Diagnostics Operations, Inc. | Method for coding information on a biosensor test strip |
US8206565B2 (en) | 2003-06-20 | 2012-06-26 | Roche Diagnostics Operation, Inc. | System and method for coding information on a biosensor test strip |
CN1846131B (zh) | 2003-06-20 | 2012-01-18 | 霍夫曼-拉罗奇有限公司 | 制备窄的均匀试剂条的方法和试剂 |
EP1671096A4 (en) | 2003-09-29 | 2009-09-16 | Pelikan Technologies Inc | METHOD AND APPARATUS FOR PROVIDING IMPROVED SAMPLE CAPTURING DEVICE |
US9351680B2 (en) | 2003-10-14 | 2016-05-31 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a variable user interface |
US20050153309A1 (en) * | 2003-12-22 | 2005-07-14 | David Hoon | Method and apparatus for in vivo surveillance of circulating biological components |
US7553625B2 (en) * | 2003-12-22 | 2009-06-30 | John Wayne Cancer Institute | Method and apparatus for in vivo collection of circulating biological components |
WO2005065414A2 (en) | 2003-12-31 | 2005-07-21 | Pelikan Technologies, Inc. | Method and apparatus for improving fluidic flow and sample capture |
US7822454B1 (en) | 2005-01-03 | 2010-10-26 | Pelikan Technologies, Inc. | Fluid sampling device with improved analyte detecting member configuration |
JP2005202893A (ja) * | 2004-01-19 | 2005-07-28 | Hitachi Ltd | 記憶デバイス制御装置、ストレージシステム、プログラムを記録した記録媒体、情報処理装置、及びストレージシステムの制御方法 |
US8828203B2 (en) | 2004-05-20 | 2014-09-09 | Sanofi-Aventis Deutschland Gmbh | Printable hydrogels for biosensors |
US9775553B2 (en) * | 2004-06-03 | 2017-10-03 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a fluid sampling device |
US9820684B2 (en) | 2004-06-03 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a fluid sampling device |
US7569126B2 (en) | 2004-06-18 | 2009-08-04 | Roche Diagnostics Operations, Inc. | System and method for quality assurance of a biosensor test strip |
GB0414550D0 (en) * | 2004-06-29 | 2004-08-04 | Oxford Biosensors Ltd | Electrochemical sensing method |
US8652831B2 (en) | 2004-12-30 | 2014-02-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for analyte measurement test time |
US7725148B2 (en) | 2005-09-23 | 2010-05-25 | Medtronic Minimed, Inc. | Sensor with layered electrodes |
KR100735898B1 (ko) * | 2006-08-25 | 2007-07-04 | 한국기계연구원 | 휴대용 미세 혈액 분리기 |
WO2008078263A1 (en) * | 2006-12-21 | 2008-07-03 | Koninklijke Philips Electronics N.V. | Aperture biosensor with trenches |
CA2697164A1 (en) * | 2007-07-26 | 2009-01-29 | Agamatrix, Inc. | Electrochemical test strips |
US9386944B2 (en) | 2008-04-11 | 2016-07-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for analyte detecting device |
US9375169B2 (en) | 2009-01-30 | 2016-06-28 | Sanofi-Aventis Deutschland Gmbh | Cam drive for managing disposable penetrating member actions with a single motor and motor and control system |
US8965476B2 (en) | 2010-04-16 | 2015-02-24 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
EP2721407B1 (en) * | 2011-06-15 | 2017-09-20 | Pfaff, Tim | Plasma or serum separator |
TW201437636A (zh) * | 2013-03-22 | 2014-10-01 | Ichia Tech Inc | 生物液體的測試片製作方法及其結構 |
US20140318278A1 (en) * | 2013-04-24 | 2014-10-30 | Honeywell International Inc. | Particle imaging utilizing a filter |
CN104569088B (zh) * | 2014-12-25 | 2017-06-13 | 北京怡成生物电子技术股份有限公司 | 电化学法血液检测试纸条及其制造方法 |
EP3468477B1 (en) | 2016-06-09 | 2023-08-23 | Haimachek, Inc. | Collector for detection and reversible capturing of cells from body fluids in vivo |
JP7243994B2 (ja) * | 2018-04-25 | 2023-03-22 | ビービービー インコーポレイテッド | 血液分析装置 |
WO2019208847A1 (ko) * | 2018-04-25 | 2019-10-31 | 주식회사 비비비 | 혈액 분석 장치 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0654304B2 (ja) | 1986-08-28 | 1994-07-20 | 松下電器産業株式会社 | バイオセンサ |
JP2502666B2 (ja) * | 1988-01-29 | 1996-05-29 | 松下電器産業株式会社 | バイオセンサ及びその製造方法 |
EP0663446B1 (en) * | 1993-12-29 | 2000-03-22 | Mochida Pharmaceutical Co., Ltd. | Electrochemical assay method and novel p-phenylenediamine compound |
DE69720391T2 (de) | 1996-12-20 | 2004-02-12 | Matsushita Electric Industrial Co., Ltd., Kadoma | Cholesterinsensor und Verfahren zu seiner Herstellung |
JP3487410B2 (ja) * | 1998-05-29 | 2004-01-19 | 松下電器産業株式会社 | バイオセンサ |
ES2260305T3 (es) * | 2000-07-31 | 2006-11-01 | Matsushita Electric Industrial Co., Ltd. | Biosensor. |
JP4183902B2 (ja) | 2000-12-27 | 2008-11-19 | 松下電器産業株式会社 | バイオセンサ |
-
2001
- 2001-05-22 JP JP2001152868A patent/JP4213361B2/ja not_active Expired - Fee Related
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2002
- 2002-05-17 CN CNB028018044A patent/CN1207563C/zh not_active Expired - Fee Related
- 2002-05-17 EP EP02771728A patent/EP1318396B1/en not_active Expired - Lifetime
- 2002-05-17 WO PCT/JP2002/004826 patent/WO2002095385A1/ja active Application Filing
- 2002-05-17 US US10/363,589 patent/US6706232B2/en not_active Ceased
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103424564A (zh) * | 2012-05-18 | 2013-12-04 | 爱科来株式会社 | 生物传感器 |
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US6706232B2 (en) | 2004-03-16 |
EP1318396B1 (en) | 2012-08-29 |
JP4213361B2 (ja) | 2009-01-21 |
JP2002340839A (ja) | 2002-11-27 |
EP1318396A1 (en) | 2003-06-11 |
USRE39390E1 (en) | 2006-11-14 |
EP1318396A4 (en) | 2006-05-24 |
CN1463360A (zh) | 2003-12-24 |
WO2002095385A1 (fr) | 2002-11-28 |
US20030183519A1 (en) | 2003-10-02 |
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