CN1193776C - Medicine for treating congestive heart failure and its prepn - Google Patents
Medicine for treating congestive heart failure and its prepn Download PDFInfo
- Publication number
- CN1193776C CN1193776C CNB00129444XA CN00129444A CN1193776C CN 1193776 C CN1193776 C CN 1193776C CN B00129444X A CNB00129444X A CN B00129444XA CN 00129444 A CN00129444 A CN 00129444A CN 1193776 C CN1193776 C CN 1193776C
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- radix
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- extractum
- material powder
- rhizoma chuanxiong
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Abstract
The present invention relates to a medicine for treating congestive heart failure and a preparation method thereof. The preparation method has the technical characteristics that the preparation method comprises the following steps: soaking 40 to 60 wt% of hemlock parsley and 40 to 60 wt% of water plantain in alcohol, successively drying and pulverizing; sieving to prepare raw material powder; preparing extractum from the following raw material components: 8 to 12 wt% of hemlock parsley, 8 to 12 wt% of water plantain, 12 to 18 wt% of red ginseng, 17 to 23 wt% of astragalus root, 12 to 18 wt% of prepared common monkshood daughter root, 12 to 18 wt% of semen tingli, 8 to 12 wt% of red sage root and 3 to 7 wt% of rehmannia root; mixing the raw material powder and the extractum, and putting the mixture into a multi-function extractor; soaking the mixture by adding water, and decocting extracting solution by a leaching method; then, concentrating the extracting solution into thick extractum for standby; finally, according to the following components, putting 25 to 35 wt% of raw material powder and 65 to 75 wt% of extractum into a granulator to prepare granules, and drying the granules to obtain the medicine. The medicine has no toxic or side effect.
Description
The present invention relates to a kind of medicine and preparation method thereof, specifically a kind of treatment congestive heart failure medicament and preparation method thereof.
We know that chronic heart failure is the inevitable outcome that multiple cardiovascular disease develops into the later stage, are one of common clinically critical illnesses, have become current medical matters circle and have needed one of problem of solution badly.Modern medicine recognizes that it exists easy poisoning respectively, causes hypotension, many thorny problems such as drug resistance and electrolysis disorder when using heart tonifying, expander, diuretic to control its symptom.The Chinese medicine treatment that is used for anti-heart failure has in recent years demonstrated its advantage day by day, yet up to the present, the special-purpose Chinese formulated products of the anti-heart failure that more satisfactory and typing is produced in batches is not seen both at home and abroad as yet.
Purpose of the present invention is exactly in order to overcome above-mentioned the deficiencies in the prior art, and a kind of treatment congestive heart failure Chinese patent medicine preparation that has no side effect and preparation method thereof is provided.
For achieving the above object, the present invention can realize by following measure:
A kind of treatment congestive heart failure Chinese patent medicine preparation, adopting Rhizoma Chuanxiong, Rhizoma Alismatis, Radix Ginseng Rubra, the Radix Astragali, Radix Aconiti Lateralis Preparata, Semen Lepidii (Semen Descurainiae), Radix Salviae Miltiorrhizae, the Radix Rehmanniae is that feedstock production forms, it can obtain with following method: Rhizoma Chuanxiong, Rhizoma Alismatis drying and crushing are got raw material powder, Rhizoma Chuanxiong, Rhizoma Alismatis, Radix Ginseng Rubra, the Radix Astragali, Radix Aconiti Lateralis Preparata, Semen Lepidii (Semen Descurainiae), Radix Salviae Miltiorrhizae, the Radix Rehmanniae soak extractum, raw material powder and extractum are made graininess in granulation machine, it is characterized in that raw material powder mixes with the part by weight of extractum by raw material powder 25-35%, extractum 65-75%; The raw material weight component is Rhizoma Chuanxiong 40-60%, Rhizoma Alismatis 40-60% when producing raw material powder; The raw material weight component is Rhizoma Chuanxiong 8-12%, Rhizoma Alismatis 8-12%, Radix Ginseng Rubra 12-18%, Radix Astragali 17-23%, Radix Aconiti Lateralis Preparata 12-18%, Semen Lepidii (Semen Descurainiae) 12-18%, Radix Salviae Miltiorrhizae 8-12%, Radix Rehmanniae 3-7% when producing extractum.
A kind of method of making treatment congestive heart failure medicament, its technical characterictic is: at first the weight with cleaning is that the mixed an amount of alcohol-pickled processing after drying with 75% of Rhizoma Chuanxiong 40-60%, Rhizoma Alismatis 40-60% is pulverized, and mistake 100 mesh sieves carry out screen analysis and prepare raw material powder; By weight that Rhizoma Chuanxiong 8-12%, Rhizoma Alismatis 8-12%, Radix Ginseng Rubra 12-18%, Radix Astragali 17-23%, Radix Aconiti Lateralis Preparata 12-18%, Semen Lepidii (Semen Descurainiae) 12-18%, Radix Salviae Miltiorrhizae 8-12%, the Radix Rehmanniae 3-7% of cleaning is mixed, place in the Chinese medicine multi-functional extractor, soak more than 8 hours, fry in shallow oil extraction 3 times with extraction, merge extractive liquid,, reconcentration become thick extractum shape standby; Then raw material powder and extractum are mixed placing granulation machine to make graininess by the part by weight of raw material powder 25-35%, extractum 65-75%, and carry out oven dry below 60 ℃.
The invention will be further described below in conjunction with accompanying drawing:
Processing technique of the present invention is simple, and the treatment congestive heart failure reagent cost of being produced is low, has no side effect, and can treat congestive heart failure effectively.
Describe the present invention below by embodiment:
Embodiment one:
It is mixed with Rhizoma Alismatis 60 at first to get clean Rhizoma Chuanxiong 40 by following component (weight %), and the raw material gross weight is 50 kilograms, adds concentration then and be 75% an amount of alcohol-pickled processing, pulverizes after the drying, and carrying out screen analysis through 100 mesh sieves then, to make raw material powder standby.It is evenly mixed to get clean Rhizoma Chuanxiong 10, Rhizoma Alismatis 10, Radix Ginseng Rubra 15, the Radix Astragali 20, Radix Aconiti Lateralis Preparata 15, Semen Lepidii (Semen Descurainiae) 15, Radix Salviae Miltiorrhizae 10, the Radix Rehmanniae 5 by following component (weight %) again, gross weight is 200 kilograms, place and soak more than 8 hours in the Chinese medicine multi-functional extractor, fry in shallow oil and carry 3 times with soaking the body method, 2 hours for the first time, 1.5 hours for the third time for the second time, merge extractive liquid, then, reconcentration becomes thick extractum shape standby.
By following component (weight %) aforementioned base materials powder 30 and mixed being placed on of the ratio of extractum 70 are made graininess in the granulation machine then, drying below 60 ℃ then.
At last, adopt the sterilization of " oxirane " sterilizing methods, aforementioned particles shape medicine is sub-packed in " 0 " number capsule, every 0.5g is packaged in the sterilized bottle.
The present invention is with benefiting QI for activating blood circulation, and warming YANG to promote diuresis is a principle, help soothing the liver with yin nourishing, Radix Ginseng Rubra in the side, reinforce functional activities of the hearts such as the Radix Astragali, but motive foot controlling blood and vessel then, the capable then blood of gas is capable; The Radix Aconiti Lateralis Preparata warming and recuperating the kidney-YANG has the meaning of " nourishing renal yang to restrict excessive yin is with the be shaded or hidden for foliage that disappears "; Blood circulation promoting and blood stasis dispelling such as Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong; Roripa is gone through son and is joined the Rhizoma Alismatis eliminating the pathogens from the lung and disappear and stop up the diuretic that eliminates the phlegm; The Radix Rehmanniae the moon that nourishes heart, all medicines share the effect that can play the beneficial motive, Tong Xinmai, warm heart-yang, dissipating blood stasis knot.Has temperature and not dry, benefit and oiliness, row and the characteristics of not loosing, keeping and not stagnating.
But each raw material of the present invention also embodiment of the listed ratio of according to the form below (weight portion) is realized.Its processing technique is identical with enforcement one.
The present invention gets clean Rhizoma Chuanxiong and Rhizoma Alismatis can be by the mixed preparation of following component (weight %) raw material powder.
| Rhizoma Chuanxiong | Rhizoma Alismatis | |
| 1 | 60 | 40 |
| 2 | 50 | 50 |
| 3 | 45 | 55 |
| 4 | 55 | 45 |
The present invention gets Rhizoma Chuanxiong, Rhizoma Alismatis, Radix Ginseng Rubra, the Radix Astragali, Radix Aconiti Lateralis Preparata, Semen Lepidii (Semen Descurainiae), Radix Salviae Miltiorrhizae, the Radix Rehmanniae of cleaning and produces extractum by following component (weight %) mixing.
| Rhizoma Chuanxiong | Rhizoma Alismatis | Radix Ginseng Rubra | The Radix Astragali | Radix Aconiti Lateralis Preparata | Semen Lepidii (Semen Descurainiae) | Radix Salviae Miltiorrhizae | The Radix Rehmanniae | |
| 1 | 8 | 11 | 17 | 19 | 14 | 17 | 8 | 6 |
| 2 | 12 | 8 | 12 | 23 | 16 | 15 | 11 | 3 |
| 3 | 11 | 9 | 15 | 17 | 18 | 16 | 9 | 5 |
| 4 | 9 | 9 | 18 | 18 | 12 | 16 | 11 | 7 |
The present invention gets aforesaid raw material powder and extractum mixes in order to the preparation granule by following component (weight %).
| Raw material powder | Extractum | |
| 1 | 25 | 75 |
| 2 | 35 | 65 |
| 3 | 27 | 73 |
| 4 | 32 | 68 |
Claims (2)
1. treat the congestive heart failure medicament for one kind, adopting Rhizoma Chuanxiong, Rhizoma Alismatis, Radix Ginseng Rubra, the Radix Astragali, Radix Aconiti Lateralis Preparata, Semen Lepidii (Semen Descurainiae), Radix Salviae Miltiorrhizae, the Radix Rehmanniae is that feedstock production forms,
It can obtain with following method: Rhizoma Chuanxiong, Rhizoma Alismatis drying and crushing are got raw material powder, Rhizoma Chuanxiong, Rhizoma Alismatis, Radix Ginseng Rubra, the Radix Astragali, Radix Aconiti Lateralis Preparata, Semen Lepidii (Semen Descurainiae), Radix Salviae Miltiorrhizae, the Radix Rehmanniae soak extractum, raw material powder and extractum are made graininess in granulation machine, it is characterized in that raw material powder mixes with the part by weight of extractum by raw material powder 25-35%, extractum 65-75%; The raw material weight component is Rhizoma Chuanxiong 40-60%, Rhizoma Alismatis 40-60% when producing raw material powder; The raw material weight component is Rhizoma Chuanxiong 8-12%, Rhizoma Alismatis 8-12%, Radix Ginseng Rubra 12-18%, Radix Astragali 17-23%, Radix Aconiti Lateralis Preparata 12-18%, Semen Lepidii (Semen Descurainiae) 12-18%, Radix Salviae Miltiorrhizae 8-12%, Radix Rehmanniae 3-7% when producing extractum.
2. make the method for the treatment of the congestive heart failure medicament for one kind, it is characterized in that: at first the weight with cleaning is that the mixed an amount of alcohol-pickled processing after drying with 75% of Rhizoma Chuanxiong 40-60%, Rhizoma Alismatis 40-60% is pulverized, and mistake 100 mesh sieves carry out screen analysis and prepare raw material powder; By weight that Rhizoma Chuanxiong 8-12%, Rhizoma Alismatis 8-12%, Radix Ginseng Rubra 12-18%, Radix Astragali 17-23%, Radix Aconiti Lateralis Preparata 12-18%, Semen Lepidii (Semen Descurainiae) 12-18%, Radix Salviae Miltiorrhizae 8-12%, the Radix Rehmanniae 3-7% of cleaning is mixed, place in the Chinese medicine multi-functional extractor, soak more than 8 hours, fry in shallow oil extraction 3 times with extraction, merge extractive liquid,, reconcentration become thick extractum shape standby; Then raw material powder and extractum are mixed placing granulation machine to make graininess by the part by weight of raw material powder 25-35%, extractum 65-75%, and carry out oven dry below 60 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB00129444XA CN1193776C (en) | 2000-12-28 | 2000-12-28 | Medicine for treating congestive heart failure and its prepn |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB00129444XA CN1193776C (en) | 2000-12-28 | 2000-12-28 | Medicine for treating congestive heart failure and its prepn |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1360900A CN1360900A (en) | 2002-07-31 |
| CN1193776C true CN1193776C (en) | 2005-03-23 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB00129444XA Expired - Fee Related CN1193776C (en) | 2000-12-28 | 2000-12-28 | Medicine for treating congestive heart failure and its prepn |
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| Country | Link |
|---|---|
| CN (1) | CN1193776C (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100356952C (en) * | 2005-12-14 | 2007-12-26 | 惠汝太 | Chinese medicinal composition for treating heart failure and oral preparation |
| WO2008154812A1 (en) * | 2007-06-15 | 2008-12-24 | Hebei Yiling Medicine Research Institute Co. Ltd. | A new use of traditional chinese medical composition |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60330679D1 (en) * | 2002-08-20 | 2010-02-04 | Univ Singapore | PHYTOPROGESTOGENIC EXTRACTS FROM RHIZOMA LIGUSTICUM CHUANXIONG AND ITS USES |
| CN101085200B (en) * | 2007-06-12 | 2010-05-19 | 王清海 | Traditional Chinese medicine composition for treating heart failure and preparation method thereof |
| CN104288588A (en) * | 2014-11-04 | 2015-01-21 | 王慧 | Preparation capable of invigorating splenic yang and circulation of blood for yang asthenia chill type rheumatic heart disease and preparation method of preparation |
| CN111110747A (en) * | 2020-01-15 | 2020-05-08 | 河北中医学院 | Traditional Chinese medicine formula for treating chronic heart failure, preparation thereof and preparation method of preparation |
| CN114010707B (en) * | 2021-12-15 | 2022-10-25 | 重庆希尔安药业有限公司 | Pharmaceutical composition for treating pulmonary heart disease and preparation method and application thereof |
-
2000
- 2000-12-28 CN CNB00129444XA patent/CN1193776C/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100356952C (en) * | 2005-12-14 | 2007-12-26 | 惠汝太 | Chinese medicinal composition for treating heart failure and oral preparation |
| WO2008154812A1 (en) * | 2007-06-15 | 2008-12-24 | Hebei Yiling Medicine Research Institute Co. Ltd. | A new use of traditional chinese medical composition |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1360900A (en) | 2002-07-31 |
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