CN1183921C - Medicine for treating depression via head acupoint osmosis - Google Patents

Abstract

The present invention relates to a medicine for treating depression, which is developed and prepared according to the treatment principle of a near taking method that the pathogenic factors are from the brain, and the brain is treated, wherein the medicine is penetrated into the brain by head acupuncture points to treat depression. The medicine is prepared by using a plurality of kinds of traditional Chinese medicines of licorice root, wheat, Chinese date, indian bread with hostwood, etc. as a basic formula and using a scientific processing method. The medicine has fully the efficacy of dispersing the stagnated liver qi for relieving the qi stagnation, invigorating the spleen for the joint operation, purging the pathogenic fire and tranquilizing. Moreover, the medicine has excellent effect on treating various kinds of depression.

Description

Can treat the medicine of depression by head acupoint osmosis

Content of the present invention belongs to the fabricating technology field of medicine, relates to a kind of medicine that can be used for treating depression.

Depression belongs to neurosal a kind of, be the disease of the slight imbalance of brain function that causes by Nervous and Mental Factors, its clinical manifestation for be in a very depressed state, sighing frequently, feeling of oppression and pain in the chest, migratory pain, palpitation and amnesia, stagnated QI transforming into fire, insomnia and dreamful sleep, irritability are susceptible to fright, oneself crime of self-accusation, being about to cry due to sadness, etc. disease.Motherland's medical research is thought the cause of disease of depression at brain, how by feelings will not freely, for a long time must the stagnation of QI, depression of liver-QI, lose in bar reach or disturbing the mind upwards due to.Traditional Chinese and western medicine medication that is used for the treatment of depression mainly contains Yueju Wan, six kinds of stagnation-syndromes soup, Clomipramine etc., and its route of administration is for oral administration or intramuscular injection.Above-mentioned traditional therapy has three big deficiencies in practical clinical: the one, and traditional therapeutic modality makes a large amount of Chinese medicine and western medicine flood irrigation whole bodies, so that arrive that old complaint---the medicine of brain is few, and most of drug wastage is in other the anosis at all organ-tissue except that brain, cause the significant wastage of medicine, therefore producing little effect of traditional remedies causes very most patients with depression cannot be cured all one's life; The 2nd, traditional administering mode is owing to the deactivation of medicine through liver, and valid density is difficult in its blood estimates; The 3rd, above-mentioned traditional medication generally all has certain toxic and side effects to human body, depression the time, often may cause other disease with its treatment or control because of its toxic and side effects, patient's old complaint is not eliminated and adds new disease.

The objective of the invention is at the aforementioned existing in prior technology weak point in this area, a kind of special-purpose medicine that can realize the effect of treatment depression by head acupoint osmosis is provided.

The preparation scheme of medicine of the present invention comes from motherland's medical science about traditional determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs thoughts such as " inner disease outer treat ", " treatment must aim at the pathogenesis of disease ", and it is that the designer obtains by concentrated summary development according to clinical practice for many years and on modern pharmacology scientific experiments basis.Depression is the disease of the slight imbalance of brain function, its diseased region is unquestionable at brain, for this reason, designer of the present invention has proposed the proximal selection of points Therapeutic Principle of " old complaint is at brain; cure from brain ", when research absorbs the traditional remedies strong point, a kind of prescription science is developed in summary, easy to prepare, the special-purpose medicine of Tong Guo the head acupoint osmotherapy treatment depression that has no side effect, during clinical treatment, use the therapeutic modality of this head acupoint drug osmotic to overcome routine treatment " old complaint is at brain " effectively, a large amount of systemic administrations, so that waste reaches the too big shortcoming of side effect too greatly, keep away the fraud of its medicine flood irrigation whole body, the far worry of its liver deactivation, anti-its mistake beyond one's ability to help, subtract the too big evil of its toxic and side effects, radically reform, dig radical cure originally, come straight to the point, beat Serpentis and take the lead, the valid density that makes medicine enter patient's diseased region increases, and imitates merit doubly with patent medicine half.According to above-mentioned Therapeutic Principle and cooperate its therapy, drug effects that designer of the present invention is more selected are concentrated and easily for head acupoint infiltrates the Chinese medicine ingredients side of being prepared into that absorbs, just the medicine in is processed by all herbal medicines that comprise Radix Glycyrrhizae, Semen Tritici aestivi, Fructus Jujubae, Radix Ginseng, Poria cum Radix Pini, Radix Polygalae, Radix Curcumae, Cortex Albiziae, Rhizoma Coptidis, Cinnabaris.Full side has the effect that dispersing the stagnated live-QI to relieve the stagnation of QI, spleen invigorating and battalion, pathogenic fire purging are calmed the nerves, and has fabulous effect aspect the treatment of depression, can significantly reduce or eliminate the threat of this disease to health of people.

The proportioning value that constitutes every part of prescription medicine in this medicine is: 4～15 unit of weights of Radix Glycyrrhizae; 6～30 unit of weights of Semen Tritici aestivi; 2～6 unit of weights of Fructus Jujubae; 1～3 unit of weight of Radix Ginseng; 4～15 unit of weights of Poria cum Radix Pini; 2～6 unit of weights of Radix Polygalae; 4～15 unit of weights of Radix Curcumae; 3～9 unit of weights of Cortex Albiziae; 1～3 unit of weight of Rhizoma Coptidis; 1～3 unit of weight of Cinnabaris.

In pharmaceutical formulation of the present invention, GANMAI DAZAO TANG is monarch, and it is strongly fragrant to control terrified compassion; The Radix Ginseng strongly invigorating primordial QI is controlled palpitation and insomnia; It is forgetful that Poria cum Radix Pini also controls palpitation and insomnia; The Radix Polygalae Fructus Alpiniae Oxyphyllae of calming the nerves is reduced phlegm, and share benefiting QI and nourishing blood and calms the nerves; The Radix Curcumae blood-activating and qi-promoting; The Cortex Albiziae resolving depression of calming the nerves; The Rhizoma Coptidis clearing heat and relieving fidgetness; The arresting convulsion of Cinnabaris tranquilizing mind.Above-mentioned all medicines share, and can receive the merit that dispersing the stagnated live-QI to relieve the stagnation of QI, spleen invigorating and battalion, pathogenic fire purging are calmed the nerves altogether, for controlling various depressions, hypochondriacal efficacious prescriptions.

In concrete the enforcement, the dosage form of medicine is made the powdered adhesive wafer that can be used for sticking and the two kinds of products of aqueous spray that can be used for sprayed coating by the essential drugs prescription.The preparation method of capsule is divided two kinds: wherein the method for making of I capsule is 3/10ths of Chinese medicine preparation total amount to be measured be ground into impalpable powder, with the extract mixing of impalpable powder with residue Chinese medicine, incapsulates heavily about 0.3 gram of every capsules medicine again; The method for making of II capsule is that the Chinese medicine powder that will provide by formula ratio is broken into fine powder, sieves, mixing, incapsulate heavy also about 0.3 gram of every capsules medicine.The preparation method of aqueous spray is: the Chinese medicine in the formula ratio is added water to flood medical material, with slow fire boiling, when treating that water evaporates surfaces medical material, add water logging and do not have medical material to fry in shallow oil again, decoct so repeatedly three times, each 1～1.5 hour time spent, collecting decoction filters, make filtrate being concentrated to have only four/for the moment, it is cold to dry in the air, and adds antiseptic at last, promptly makes the spray medicinal liquid.

Clinical case is observed and curative effect

453 examples of clinical observation case once in development process of the present invention.

One, administrated method:

According to the human anatomy theory, the all caves of cranium brain all have the nerve and the tremulous pulse that directly or indirectly lead to brain to distribute, and from science of acupuncture and moxibustion angle, there is good effect at all acupuncture points such as the windy mansion of head, Naohu, Qianghian, Hou Ding, Baihui, halogen meeting, Shenting, five places, Luoque, Tianzhu, Muchuang, Wangue, jaw are detested, Zhengying, Benshen, Xuanlu, Xuanli, Shuaigu, fubai, a dimension, Meichong, Qucha to the treatment depression, for this reason, choose above-mentioned place of patient's head or acupuncture point, many places as the drug osmotic acupuncture point, first water is cleaned scalp, dry before the drug of topical application; The hair at place, separately selected acupuncture point at selected place, acupuncture point, or is sprinkling upon selected place, acupuncture point with 6 I number or 15 II capsule powder medicines with the sprayed coating of concentrated solution medicine spray, and water squirts into pasty state; During with concentrated solution medicine spray or capsule sprayed coating, the diameter of drug of topical application area will have 20mm at least on the acupuncture point, every place, after medicine applies and finishes, the reuse plastic paper covers or puts on the medicated cap that is lined with plastic paper, so that the medicine maintenance is moistening, sprayed coating or application time are at 16～20 hours every day, and once-a-day, 30 days is a course of treatment.

Two, criterion of therapeutical effect: divide recovery from illness, produce effects, improvement and invalid four kinds.Wherein the state of an illness does not recur after five courses of treatment, symptoms of depression disappearance person is recovery from illness by this medicine of clinical usefulness; The most of disappearance person of medication retarded depression symptom five courses of treatment is a produce effects; Medication retarded depression symptom five courses of treatment person of taking a favorable turn is for taking a turn for the better; And have no variation person for invalid with this therapy symptoms of depression five courses of treatment.

Three, observed result: 453 case patients of this group are after treatment, and 359 examples of fully recovering account for 79.3% of total treatment case load, and produce effects 44 examples account for 9.7%, and 31 examples that take a turn for the better account for 6.8%, and invalid 19 examples account for 4.2%.

Claims (4)

1, a kind of medicine that can treat depression by head acupoint osmosis is characterized in that said medicine made by 4～15 unit of weights of Radix Glycyrrhizae, 6～30 unit of weights of Semen Tritici aestivi, 2～6 unit of weights of Fructus Jujubae, 1～3 unit of weight of Radix Ginseng, 4～15 unit of weights of Poria cum Radix Pini, 2～6 unit of weights of Radix Polygalae, 4～15 unit of weights of Radix Curcumae, 3～9 unit of weights of Cortex Albiziae, 1～3 unit of weight of Rhizoma Coptidis, 1～3 unit of weight of Cinnabaris.

2, the preparation method of the medicine of treatment depression as claimed in claim 1 is characterized in that 3/10ths amounts of Chinese medicine preparation total amount are ground into impalpable powder, with the extract mixing of impalpable powder with residue Chinese medicine, incapsulates again.

3, the preparation method of the medicine of treatment depression as claimed in claim 1 is characterized in that the Chinese medicine powder that will provide by formula ratio is broken into fine powder, sieves, mixing, incapsulates.

4, the preparation method of the medicine of treatment depression as claimed in claim 1 is characterized in that the Chinese medicine in the formula ratio added water to and floods medical material, with slow fire boiling, when treating that water evaporates surfaces medical material, add water logging and do not have medical material to fry in shallow oil again, decoct so repeatedly three times, each 1～1.5 hour time spent, collecting decoction, filter, make filtrate being concentrated to have only four/for the moment, it is cold to dry in the air, add antiseptic at last, promptly make the spray medicinal liquid.