CN118253414A - Compatible multi-object centrifugal module and automatic processing module - Google Patents

Abstract

The invention relates to the technical field of medical equipment, and aims to solve the problems that unbalanced vibration of a centrifugal module can not be absorbed to the maximum extent and the vibration of the centrifugal module has great influence on other parts in the prior art, and provides a compatible multi-object centrifugal module and an automatic processing module, wherein the compatible multi-object centrifugal module comprises a vibration absorption base; the top of the vibration absorbing base is provided with a centrifugal supporting frame which is connected with the vibration absorbing base; the centrifugal support frame is connected with a centrifugal driving motor, an output shaft of the centrifugal driving motor is connected with a rotary table, a plurality of groups of bearing frames of various centrifugal objects are arranged in the circumferential direction of the rotary table, each group of the plurality of groups of bearing frames comprises a plurality of bearing units, and the plurality of bearing units in the same group are uniformly distributed in the circumferential direction of the rotary table at the same preset interval angle. The centrifugal device has the advantages that vibration of the centrifugal module is absorbed to the maximum extent, the influence of the vibration on other parts is small, the solution or the reagent hardly causes larger error in the reaction system, the centrifugal efficiency is high, and the efficient and automatic operation of the system is ensured.

Description

Compatible multi-object centrifugal module and automatic processing module

Technical Field

The invention relates to the technical field of medical equipment, in particular to a compatible multi-object centrifugal module and an automatic processing module.

Background

The processing of biological related samples is the key point of health management and diagnosis and treatment in recent years, along with the development of health-level attention and diagnosis and treatment technologies of people, in-vitro diagnosis technology with low pollution risk and less interference effect on human bodies or objects to be detected is the key development technology of diagnosis and treatment, the current in-vitro diagnosis technology comprises various different types of detection technologies, and more detection technologies comprising immunoluminescence, electrochemiluminescence, PCR fluorescent amplification and the like are applied, wherein most detection objects perform reaction in a tiny amount, so that the condition that a reaction reagent is fully contacted with a sample liquid or a derivative thereof is a precondition for accurate reaction execution; at present, in order to improve the reaction detection efficiency, a sample processing system and a detection system are generally designed into a full-automatic form, the high efficiency of the automatic processing system requires that a sample can be rapidly processed within a limited time and can be fully mixed with a reaction reagent, and special reactions such as a reaction container used by a PCR fluorescent amplification technology have smaller volume, tiny bubbles can be generated in the process of adding the reagent, capillary force born by mixed reaction liquid in the smaller reaction container becomes main resistance, even the action of the capillary force is stronger than the action of gravity, and thus, both the PCR amplification and the subsequent detection result can be influenced; in the laboratory-stage detection or the small-batch detection, a separate centrifuge can be configured to enable a reaction tube which is constructed by a system to perform high-speed centrifugation operation before amplification, so that bubbles which are possibly generated can be removed, and acceleration and uniform mixing of different reagents can be realized by utilizing centrifugal force to a certain extent, so that the centrifuge is also reasonably and urgently introduced into an automatic processing system of a sample as an essential module.

Chinese patent No. CN113617541B discloses a scheme in which a centrifugal module is arranged in a sample processing system, and defines a scheme for implementing centrifugal processing of a plurality of samples simultaneously by using meshing transmission from a layout relationship and a detailed structure of the centrifugal module; the scheme disclosed in the U.S. patent 7195737B2 is characterized in that a plurality of centrifugal modules are arranged in a plurality of vertically arranged isolation spaces, the centrifugal modules are pulled out and loaded on a centrifuged object through an openable or closable pulling structure, and then the centrifugal modules are closed to finish centrifugation, so that the working efficiency is high; US6455002B1 focuses on the vibration problem possibly caused by the weight difference of the centrifuged objects, a weighing device is arranged in the system, and the weighing result of the weighing device is adopted before centrifugation to allocate different positions for the bearing tray, so that the unbalance problem in the centrifugation process is reduced; the centrifuge module disclosed in EP2660608B1 has a solution in which the sample tubes are arranged in a specific order for different carrying positions, and the loaded sample tubes can be trimmed according to the degree of imbalance of the rotation, or a slight amount of other reagents can be added to the sample tubes for leveling; the Chinese patent application CN116713132A designs the rotational speed reduction control method of the centrifugal machine into an exponential fit type speed curve, and solves the problems of unstable speed reduction, vibration and the like caused by overlarge gradient of speed reduction change; US20080096749A1 proposes a new idea of balancing the instability of the rotation process, designs a wall-sandwiched structure, and fills liquid in the wall-sandwiched structure, when the weight of the centrifugal object received by the innermost side of the wall-sandwiched structure is unbalanced, the liquid in the wall-sandwiched layer can be automatically distributed until balanced under the action of centrifugal force by communicating the wall-sandwiched layers in different positions, and the design structure is complex and rarely adopted in practical application.

At present, most manufacturers design centrifugal equipment from a centrifugal imbalance generation source in an automatic sample processing system, the method is expected to reduce the vibration problem of unstable operation in the operation of a centrifugal module to a certain extent, but the vibration is difficult to avoid, and the vibration reduces the operation reliability of the whole system, so that under the scene of high precision and high reliability related to medical equipment, a centrifugal module capable of absorbing vibration, particularly a multi-centrifugal-object composite centrifugal module, is more required to be developed, and the centrifuged object has natural unequal characteristics.

Disclosure of Invention

The invention aims to provide a compatible multi-object centrifugal module and an automatic processing module, which are used for solving the problems that unbalanced vibration of the centrifugal module in the prior art cannot be absorbed to the maximum extent and the influence of vibration on other components in the operation of the centrifugal module is larger.

Embodiments of the present invention are implemented as follows:

The embodiment of the invention provides a compatible multi-object centrifugal module, which comprises a vibration absorption base;

A centrifugal support frame is arranged at the top of the vibration absorption base, and one end of the centrifugal support frame, which is close to the vibration absorption base, is detachably and fixedly connected to the top of the vibration absorption base;

The centrifugal support frame is at least partially of a hollow structure, a centrifugal driving motor is arranged in one end, far away from the vibration absorbing base, of the centrifugal support frame, an output shaft of the centrifugal driving motor is connected with a rotary table, a plurality of groups of bearing frames corresponding to a plurality of different centrifugal objects are arranged in the circumferential direction of the rotary table, each group of the plurality of groups of bearing frames comprises a plurality of bearing units, and the plurality of bearing units are uniformly distributed in the circumferential direction of the rotary table at the same preset interval angle.

By the arrangement, unbalanced vibration energy of the centrifugal module is absorbed to the greatest extent, and the vibration of the centrifugal module has small influence on other components.

Optionally: the outer wall of the center rotating shaft of the rotating table is fixedly sleeved with a centrifugal bearing, and the outer wall of the centrifugal bearing is fixedly sleeved with a centrifugal mounting disc.

The rotary table can be driven by the centrifugal driving motor to rotate around the central rotating shaft smoothly and smoothly, and running noise and running vibration degree are effectively reduced.

Optionally: a bracket assembly disc is arranged between the centrifugal mounting disc and the centrifugal supporting frame, a plurality of cushioning units are arranged between the bracket assembly disc and the centrifugal mounting disc, and the cushioning units are uniformly and alternately distributed along the circumference of the centrifugal mounting disc;

The support assembly plate is detachably and fixedly connected to the top end of the centrifugal support frame, one ends of the cushioning units are fixedly connected to the support assembly plate, and the other ends of the cushioning units are fixedly connected to the centrifugal mounting plate.

So set up, above-mentioned bradyseism unit can weaken the vibration that produces in the centrifugal operation process of above-mentioned revolving stage as primary shock-absorbing structure, guarantees centrifugal module operational reliability.

Optionally: the shock absorbing unit is made of rubber, and the hardness of the shock absorbing unit is not lower than Shore A50.

So set up, the specific intensity that above-mentioned bradyseism unit had can guarantee that above-mentioned bradyseism unit pressurized deflection is unlikely to too big, and the effectual life who improves above-mentioned bradyseism unit, the bradyseism effect is obvious.

Optionally: the vibration absorbing base is made of a nonmetallic material, and is at least one of artificial stone, natural stone, ceramics, gypsum, plastics and nonmetallic porous materials.

The vibration absorbing base is made of nonmetallic materials, the vibration transmitting inert characteristic of a basic unit formed by the nonmetallic materials is utilized, and the vibration absorbing base is configured to have a form with a preset volume according to the vibration absorbing energy storage energy requirement, so that vibration can be effectively absorbed.

Optionally: the multiunit bears the frame and contains the expansion consumable frame of multiunit tube type and is used for bearing the reagent pipe support of waiting the partial shipment.

So set up, above-mentioned many allies oneself with tubular amplification consumable frame is convenient for a plurality of test tubes assembly, and centrifugal motion is simultaneously made to a plurality of test tubes of being convenient for, and when above-mentioned many allies oneself with tubular amplification consumable frame had to wait centrifugal article, above-mentioned reagent pipe frame then can be as counter weight portion, can reduce the vibration degree in a plurality of test tube centrifugal operation to a certain extent, and on the contrary, when the centrifugal article of waiting on the above-mentioned reagent pipe frame needs centrifugal rotation, above-mentioned many allies oneself with tubular amplification consumable frame then can be as counter weight portion, also can reduce the vibration degree of waiting centrifugal article in centrifugal operation to a certain extent.

Optionally: the centrifugal driving motor drives the multiple groups of bearing frames to rotate at the rotation speed of 2500 rpm-5000 rpm.

The arrangement can ensure the centrifugal effect and meet the balance requirement of the vibration degree in the system operation.

Optionally: the centrifugal module further includes a centrifugal angle restricting unit for defining any inclination angle of the plurality of carrying units during centrifugal rotation.

In order to realize uniform constraint of a plurality of bearing units with lower cost and high efficiency, the constraint unit type and the configuration position of each bearing unit are the same, so that the reagent tube or the amplification consumable presents different inclined states.

Optionally: the centrifugal module further comprises a centrifugal chamber with an electric opening and closing cover plate, and the rotary table and the plurality of groups of bearing frames are arranged in the centrifugal chamber.

So configured, the above-described centrifugal chamber can reduce interactions of the centrifugal module with other components or modules.

Optionally: and one end of the centrifugal support frame, which is close to the vibration absorption base, is provided with a mounting disc, and the centrifugal support frame is connected to the top surface of the vibration absorption base through the mounting disc through bolts.

So set up, realize above-mentioned centrifugal support frame and above-mentioned base interconnect that shakes that absorbs through above-mentioned mounting disc, the effectual above-mentioned base atress area that absorbs shakes that has enlarged, and then more be favorable to dispersing the gravity that above-mentioned centrifugal support frame transmitted down, and then be favorable to vibration to carry out furthest's absorption in the transmission process, simultaneously, can greatly weaken even eliminate the vibration that produces because centrifugal operation, so can avoid centrifugal module configuration to the influence of other operation modules in the system.

Optionally: a plurality of strengthening ribs are arranged on the outer wall of the centrifugal support frame, the strengthening ribs are uniformly distributed along the radial direction of the centrifugal support frame, and the strengthening ribs are fixedly connected at the included angles between the mounting plate and the outer wall of the centrifugal support frame.

The strength and the stability of the centrifugal support frame can be enhanced by arranging the reinforcing ribs, and the vibration transmission is facilitated without being damaged.

Optionally: and the center rotating shaft of the rotating table is connected with a centrifugal coupling which is fixedly connected to a motor output shaft of the centrifugal driving motor.

By means of the arrangement, the centrifugal coupling can achieve 1:1 transmission ratio output, the fact that the rotating vibration of the rotating table is relatively small is guaranteed, and running noise and running vibration degree are reduced.

Optionally: the outside of the centrifugal coupling is provided with a sheath, the upper part of the sheath is detachably connected to the centrifugal mounting disc, and the lower end of the sheath is detachably connected to the centrifugal driving motor.

In this setting, in the centrifugal operation, the vibration that above-mentioned centrifugal driving motor operation produced also will transmit to above-mentioned centrifugal mounting plate, and above-mentioned damping unit and above-mentioned shock absorption base can realize the effect of two-stage vibration shock absorption buffering like this.

In one implementation of the present embodiment: the automatic processing module compatible with the multi-object centrifugal module comprises a first transfer assembly and a second transfer assembly, wherein the first transfer assembly is provided with a first transfer unit and a first span, the first transfer unit is arranged on the first span and can be driven to move along X, Y and a Z axis, the second transfer assembly is provided with a second transfer unit and a second span, the second transfer unit is arranged on the second span, the movement stroke of the first span and the movement stroke of the second span are at least partially overlapped, and the arrangement of the first transfer assembly and the second transfer assembly can ensure that different transfer objects can be transferred reliably and efficiently.

By combining the description, the compatible multi-object centrifugal module and the automatic processing module disclosed by the invention have the advantages that unbalanced vibration energy of the centrifugal module is absorbed to the greatest extent, the influence of vibration on other parts in the operation of the centrifugal module is small, the fact that a solution or a reagent almost cannot cause a larger error in a reaction system due to the problem of sticking walls is ensured, the centrifugal efficiency is also ensured to be higher, and the efficient automatic operation of the system is ensured.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are needed in the embodiments will be briefly described below, it being understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and other related drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

FIG. 1 is a schematic diagram of a centrifugal module according to an embodiment of the invention;

FIG. 2 is an exploded view of a centrifugal module according to an embodiment of the invention;

FIG. 3 is a schematic view of a first view angle structure of a centrifugal module according to an embodiment of the invention;

FIG. 4 is a schematic view of a second perspective structure of a centrifugal module according to an embodiment of the invention;

FIG. 5 is a schematic diagram showing a state before centrifugation of a consumable part of a centrifugal module carrying connecting tube type in an embodiment of the invention;

FIG. 6 is a schematic diagram showing a centrifugal state of a centrifugal module carrying a connecting tube type consumable material in an embodiment of the invention;

FIG. 7 is a schematic diagram showing a state before centrifugation of a reagent carrying tube of a centrifugation module according to an embodiment of the present invention;

FIG. 8 is a schematic diagram showing a state of a centrifugation module carrying a reagent tube in centrifugation according to an embodiment of the present invention;

FIG. 9 is a schematic diagram showing a state that an opening and closing cover plate of a centrifugal module opens a centrifugal chamber according to an embodiment of the invention;

FIG. 10 is a schematic view of a centrifugal module with an openable cover closing a centrifugal chamber according to an embodiment of the invention;

FIG. 11 is a schematic view of a first transfer unit and a second transfer unit used with the present invention in accordance with an embodiment of the present invention;

fig. 12 is a partial block diagram of an automated processing system for a centrifugal module in accordance with an embodiment of the invention.

Icon: the device comprises a 1-multi-tube type amplification consumable rack, a 2-reagent tube rack, a 3-centrifugal angle constraint unit, a 4-centrifugal chamber, a 5-first transfer component, a 6-second transfer component, a 10-vibration absorption base, an 11-module base, a 20-centrifugal support frame, a 31-support assembly disk, a 32-centrifugal mounting disk, a 33-rotating table, a 50-first span beam, a 60-second span beam, a 130-centrifugal module, a 201-operation hole, a 202-strengthening rib, a 203-mounting disk, a 301-centrifugal driving motor, a 302-motor output shaft, a 303-centrifugal coupling, a 311-cushioning unit, a 331-first amplification consumable bearing unit, a 332-second amplification consumable bearing unit, 333-first reagent tube bearing unit, 334-second reagent tube bearing unit, 335-sheath, 401-cover driving motor, 402-cover plate, 403-cover plate driving belt, 404-driven wheel, 405-cover plate connecting block, 410-opening and closing cover plate, 420-chamber side plate, 510-first transfer unit, 610-second transfer unit, 701-reagent storage area, and a packaged part of consumable part.

Detailed Description

For the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments of the present invention. The components of the embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.

Thus, the following detailed description of the embodiments of the invention, as presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

Examples

Referring to fig. 1 to 12, the present embodiment eliminates the concept of eliminating the unbalance problem in the centrifugal operation process from the source, and absorbs the unbalanced vibration of the centrifugal module to the maximum in the transmission process, so that the effect that the centrifugal module operates stably and has less influence on other components can be achieved.

The embodiment provides a compatible multi-object centrifugal module, which comprises a vibration absorption base 10;

The top of the vibration absorbing base 10 is provided with a centrifugal supporting frame 20, and one end of the centrifugal supporting frame 20, which is close to the vibration absorbing base 10, is detachably and fixedly connected to the top of the vibration absorbing base 10;

The centrifugal support frame 20 is at least partially of a hollow structure, a centrifugal driving motor 301 is disposed inside one end of the centrifugal support frame 20 far away from the vibration absorbing base 10, an output shaft of the centrifugal driving motor 301 is connected with a rotating table 33, a plurality of groups of bearing frames (shown by reference numeral 331 and reference numeral 334 in fig. 1) corresponding to a plurality of different centrifugal objects are disposed in the circumferential direction of the rotating table 33, each group of the bearing frames comprises a plurality of bearing units (two groups of bearing frames are shown here to comprise 2 bearing units) and are uniformly distributed in the circumferential direction of the rotating table 33 at the same preset interval angle, when the number of bearing units in the group is 2, each bearing unit in the group is spaced by 180 degrees, when the number of bearing units in the group is 3, each bearing unit in the group is spaced by 90 degrees, and when the number of bearing units in the group is 4, the specific number of bearing units in the group is not limited here, thus unbalanced vibration in operation of the centrifugal module 130 can be weakened from the generation, and the configuration of the vibration absorbing base can absorb vibration to the maximum extent, and thus the vibration of other components of the centrifugal module 130 has less influence on vibration.

In this embodiment, the vibration absorbing base 10 is preferably a solid structure, the centrifugal support frame 20 is made of a metal material, and here may be made of common materials such as steel, iron, and aluminum alloy, at least part of the centrifugal support frame 20 is a hollow structure, and the centrifugal drive motor 301 is configured in the hollow structure, so that the self-balance of vibration waves can be formed by using the hollow space, and the vibration influence of the system can be reduced to a certain extent.

In the present embodiment, in order to conveniently assemble the centrifugal driving motor 301, the centrifugal support frame 20 is further provided with an operation hole 201.

In this embodiment, the centrifugal driving motor 301 is integrally disposed in the hollow centrifugal supporting frame 20, which can ensure a more compact structure and reduce the running noise and running vibration to a certain extent by using the hollow structure, and the centrifugal driving motor 301 is disposed on the vibration absorbing base 10, which can greatly reduce or even eliminate the vibration generated by the centrifugal operation, so that the influence of the centrifugal module 130 on other running modules in the system can be avoided, and the module base 11 is detachably connected to the bottom of the vibration absorbing base 10.

Referring to fig. 1 to 12, a centrifugal bearing (not labeled in the drawings) is fixedly sleeved on the outer wall of the central rotating shaft of the rotating table 33, and a centrifugal mounting disc 32 is fixedly sleeved on the outer wall of the centrifugal bearing, so that the rotating table 33 can be driven by the centrifugal driving motor 301 to rotate smoothly around the central rotating shaft, and the running noise and the running vibration degree are effectively reduced.

A bracket assembly disc 31 is arranged between the centrifugal mounting disc 32 and the centrifugal support frame 20, a plurality of cushioning units 311 are arranged between the bracket assembly disc 31 and the centrifugal mounting disc 32, and the plurality of cushioning units 311 are uniformly and alternately distributed along the circumferential direction of the centrifugal mounting disc 32; the detachable fixed connection of support assembly dish 31 is on the top of centrifugal support frame 20, and the equal fixed connection of a plurality of bradyseism unit 311 is on support assembly dish 31, and the equal fixed connection of the other end of a plurality of bradyseism unit 311 is on centrifugal mounting plate 32, and bradyseism unit 311 can weaken the vibration that the revolving stage 33 centrifugation operation in-process produced as primary shock-absorbing structure, guarantees centrifugal module 130 operational reliability.

The cushioning unit 311 is made of rubber, the hardness of the cushioning unit 311 is not lower than Shore A50, the specific strength of the cushioning unit 311 can ensure that the compressive deformation of the cushioning unit 311 is not too large, the service life of the cushioning unit 311 is effectively prolonged, and the cushioning effect is obvious.

The vibration absorbing base 10 is made of a non-metal material, which is artificial stone or natural stone or ceramic or gypsum or plastic, a non-metal porous material, etc., the vibration absorbing base 10 is made of a non-metal material, which utilizes the vibration transmission inertia characteristic of a base unit made of the non-metal material, and the vibration absorbing base 10 is configured to have a form with a preset volume according to the vibration absorbing energy storage requirement, and in this embodiment, the vibration absorbing base 10 is configured so that the vibration isolation coefficient between the centrifugal support frame 20 and the assembly substrate of the vibration absorbing base 10 is not more than 0.8, so as to realize more effective vibration absorption.

Referring to fig. 1 to 12, the multi-group carrier comprises a multi-tube type amplification consumable rack 1 and a reagent tube rack 2 for carrying sub-packaging, and the multi-tube type amplification consumable rack 1 is provided with a plurality of carrier units so as to facilitate the simultaneous assembly of a plurality of multi-tube type amplification consumables and realize the simultaneous centrifugal movement of a plurality of objects to be detected. When the multi-tube amplification consumable rack 1 is used for centrifuging objects, the reagent tube rack 2 can be used as a counterweight part, so that the vibration degree of the multi-tube amplification consumable in the centrifugal operation can be reduced to a certain extent, otherwise, when the objects to be centrifuged on the reagent tube rack 2 need to be centrifugally rotated, the multi-tube amplification consumable rack 1 can be used as the counterweight part, the vibration degree of the objects to be centrifuged in the centrifugal operation can be reduced to a certain extent, different types of objects to be centrifuged are configured in the circumferential direction of the rotary table, the function expansion of the centrifugal mechanism is realized, and the vibration characteristics generated in the centrifugal process of two different centrifugal objects are relatively fixed, so that the vibration absorption is easier.

In this embodiment, the multiple tube type amplification consumable rack 1 and the reagent tube rack 2 each include two carrying units, namely, a first amplification consumable carrying unit 331 and a second amplification consumable carrying unit 332, a first reagent tube carrying unit 333 and a second reagent tube carrying unit 334, two carrying units of any group of carrying racks are uniformly distributed in the circumferential direction of the rotary table 33 at 180 ° intervals, when each group of carrying rack units includes m carrying units, the m carrying units are uniformly distributed in the circumferential direction of the rotary table 33 at 360 °/m intervals, in this embodiment, m×n carrying units of different types are all arranged in the circumferential direction at equal intervals, that is, all carrying units are uniformly distributed in the circumferential direction of the central rotating shaft at 360 °/(m×n) intervals, so that vibration generated due to the difference in weight of the carrying units when different objects are centrifuged is more regular, the vibration problem eliminating method of such imbalance is also simpler, more types of materials can be adopted to absorb, that is, the vibration absorbing coefficient is higher, and vibration absorbing cost is lower, and vibration absorbing base is more cost is provided.

The centrifugal driving motor 301 drives the rotary table 33 to drive the multiple groups of bearing frames to rotate at the rotation speed of 2500 rpm-5000 rpm, so that the centrifugal effect can be ensured to achieve the requirement of optimizing the amplification detection result, and the optimal balance of the vibration degree in the operation of the compatible multi-object centrifugal module in the embodiment can be achieved, and the vibration degree in the centrifugal operation process of the module can be absorbed by the vibration absorbing base 10 more and even basically eliminated.

Referring to fig. 4, the centrifugal module 130 further includes a centrifugal angle constraint unit 3 for defining an inclination angle of the plurality of carrying units during the centrifugal rotation, in order to achieve uniform constraint of the plurality of carrying units at a lower cost and with high efficiency, each carrying unit has the same constraint unit type and configuration position, and in the drawings, the first reagent tube carrying unit 333 and the first amplification consumable carrying unit 331 are shown to be capable of freely rotating within a preset angle under the limitation of the centrifugal angle constraint unit 3, so that the reagent tube or the amplification consumable presents an inclination state during the centrifugal operation.

Referring to fig. 9 and 10, the centrifugal module 130 further includes a centrifugal chamber 4 having an electrically powered opening and closing cover plate 410, and the rotary table 33 and the plurality of sets of carriers are disposed in the centrifugal chamber 4, and the centrifugal chamber 4 can reduce interaction of the centrifugal module 130 with other components or modules.

In this embodiment, the centrifugal chamber 4 includes a chamber side plate 420 and an opening and closing cover plate 410 on the top of the side plate, the cover plate driving motor 401 can output the driving force of the opening and closing cover plate 410, the output shaft of the cover plate driving motor 401 is connected with a cover plate driving wheel 402, a cover plate driven wheel 404 is fixed at a preset distance from the cover plate driving wheel, a cover plate driving belt 403 is sleeved between the cover plate driving wheel 402 and the cover plate driven wheel 404, a cover plate connecting block 405 is further configured on the cover plate driving belt 403 and is fixedly connected with the opening and closing cover plate 410, and when the cover plate driving motor 401 outputs clockwise or anticlockwise rotational movement, the opening and closing cover plate 410 can be driven to open or close the centrifugal chamber 4, so that the influence of the centrifugal module 130 is isolated.

Referring to fig. 1 to 10, an end of the centrifugal support frame 20, which is close to the vibration absorbing base 10, is provided with a mounting plate 203, the centrifugal support frame 20 is connected to the top surface of the vibration absorbing base 10 through the mounting plate 203 by bolts, the centrifugal support frame 20 and the vibration absorbing base 10 are connected to each other through the mounting plate 203, the stress area of the vibration absorbing base 10 is effectively enlarged, further, the gravity transferred by the centrifugal support frame 20 is more favorably dispersed, and further, the vibration is favorably dispersed in the transmission process and then absorbed to the greatest extent, so that the vibration generated by centrifugal operation can be greatly weakened or even eliminated, and finally, the problem that other modules in the system may be influenced by configuring the centrifugal module 130 can be avoided.

The outer wall of the centrifugal support frame 20 is provided with a plurality of reinforcing ribs 202, the reinforcing ribs 202 are uniformly distributed along the circumferential direction of the centrifugal support frame 20, the reinforcing ribs 202 are fixedly connected at the included angle between the mounting plate 203 and the outer wall of the centrifugal support frame 20, and the strength and stability of the centrifugal support frame 20 can be enhanced by the arrangement of the reinforcing ribs 202, so that vibration transmission is facilitated without being damaged.

The center rotating shaft of the rotating table 33 is connected with a centrifugal coupling 303, the centrifugal coupling 303 is fixedly connected to a motor output shaft 302 of the centrifugal driving motor 301, the centrifugal coupling 303 can achieve 1:1 transmission ratio output, rotation vibration of the rotating table 33 is ensured to be relatively small, running noise and running vibration degree are reduced, and in some cases, a speed change mechanism can be further arranged between the motor output shaft 302 and the center rotating shaft of the rotating table 33, so that non-1:1 transmission ratio output is achieved, and the speed change mechanism is not limited in this regard.

Referring to fig. 3, the outside of the centrifugal coupling 303 is provided with a sheath 335, an upper portion of the sheath 335 is detachably connected to the centrifugal mounting plate 32, and a lower end of the sheath 335 is detachably connected to the centrifugal drive motor 301. The sheath 335 itself can be used as a mounting structure of the centrifugal driving motor 301, and in the centrifugal operation process, the vibration generated by the operation of the centrifugal driving motor 301 is also transferred to the centrifugal mounting disc 32, so that the damping unit 311 and the damping base 10 can realize the two-stage vibration damping effect.

Referring to fig. 5 and 6, fig. 5 and 6 are illustrations of different centrifugal states of the consumable supplies of the centrifugal module carrying tube type, in this embodiment, a serial operation mode of the centrifugal module 130 is shown, that is, the multi-tube type amplification consumable rack 1 of the centrifugal module 130 is centrifuged in this centrifugation operation time period, while the reagent tube rack 2 is in a vacant state in this time period, fig. 5 illustrates that a plurality of amplification tubes are placed on the first amplification consumable carrying unit 331 and the second amplification consumable carrying unit 332 which are arranged at 180 ° intervals, and of course, the specific types of the amplification consumables are not limited herein, but also single amplification tubes can be placed on the first amplification consumable carrying unit 331 and the second amplification consumable carrying unit 332 one by one, fewer amplification consumables need to be centrifuged in special cases, standby balancing consumables can be configured in the system, or centrifugation can be performed after balancing the amplification consumables which have completed centrifugation, and of course, the centrifugal module 130 can be configured to perform centrifugation operations with a single side of amplification consumables can be used in very few cases. After the configuration is completed, the centrifugal module 130 performs centrifugal rotation, the reagent tube rack 2 which is empty in the centrifugal process can be used as a counterweight part, and the vibration degree in the centrifugal rotation process can be reduced to a certain extent, due to the limitation of the centrifugal angle constraint unit 3, the first amplification consumable bearing unit 331 and the second amplification consumable bearing unit 332 can be limited in the centrifugal rotation process, and the included angle between any one of the first reagent tube bearing unit 333 and the second reagent tube bearing unit 334 and the central rotating shaft of the rotating table 33 is not more than 75 degrees, so that the solution or the reagent can be ensured to have larger error in the reaction system due to the sticking problem, and the centrifugal efficiency can be ensured to be higher.

Referring to fig. 7 and fig. 8, the comparison of different centrifugal states of the reagent tube carried by the centrifugal module 130 provided by the invention is similar to fig. 5, and the whole process is not repeated here, the multi-tube amplification consumable rack 1 in the centrifugal process can be used as a counterweight part, and also can reduce the vibration degree of the reagent tube in the centrifugal operation to a certain extent, and the centrifugal rotating speed ranges of different objects can be configured to be the same, and of course, the centrifugal rotating speed of the different objects can be configured to be higher according to the special requirements of the primer probe, and the centrifugal operation can be executed in parallel by adopting the centrifugal module 130 under some special scenes, so that the centrifugal efficiency of the system is ensured to be higher.

Referring to fig. 11 and 12, in one implementation of the present embodiment: in order to ensure that different transfer objects can be transferred reliably and efficiently, the invention is provided with two independent transfer assemblies, comprising a first transfer assembly 5 and a second transfer assembly 6, wherein the first transfer assembly 5 is provided with a first transfer unit 510 and a first span 50, the first transfer unit 510 is arranged on the first span 50, the first transfer unit 510 can be used for transferring reagent pipes, the first transfer assembly 5 can transfer the centrifugal object reagent pipes into a reagent pipe rack 2 compatible with the multi-object centrifugal module 130 in a first time period, and the first transfer unit 510 is arranged on the first span 50 and can be driven to move along X, Y and Z axes.

The second transfer unit 6 has a second transfer unit 610 and a second bridge 60, the second transfer unit 610 is configured on the second bridge 60, the second transfer unit 610 can be used for transferring the multi-tube type amplification consumable, the second transfer unit 6 can transfer the multi-tube type amplification consumable of the second type centrifugal object to the multi-tube type amplification consumable rack 1 compatible with the multi-object centrifugal module 130 in a second time period different from the first time period, and the second transfer unit 610 is configured on the second bridge 60 and can be driven to move along X, Y and Z axes. The movement stroke of the first bridge 50 and the movement stroke of the second bridge 60 are at least partially overlapped, so that the first transferring assembly 5 and the second transferring assembly 6 can be ensured to be capable of reliably and efficiently transferring different types of centrifugal objects to the centrifugal module 130, the two operations can realize the effect of no interference with each other, and the arrangement of the first transferring assembly 5 and the second transferring assembly 6 can be ensured to be capable of reliably and efficiently transferring different transferring objects.

Referring to fig. 11 and 12, in the present embodiment, the first transfer assembly 5 and the second transfer assembly 6 are disposed in an upper region of the automated processing system, the first bridge 50 can drive the first transfer unit 510 to transfer the reagent tube to be centrifuged from the reagent storage area 701 into the centrifugation module 130, the second bridge 60 can drive the second transfer unit 610 to transfer the packaged amplification supplies from the amplification supplies packaging part 702 into the centrifugation module 130, and of course, different centrifugation objects to be centrifuged can be driven by different transfer units to transfer to different positions to perform subsequent operations.

The above description is only of the preferred embodiments of the present invention and is not intended to limit the present invention, but various modifications and variations can be made to the present invention by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (10)

1. A compatible multi-object centrifugal module, characterized by:

comprises a shock absorbing base;

The top of the vibration absorption base is provided with a centrifugal support frame, and one end of the centrifugal support frame, which is close to the vibration absorption base, is detachably and fixedly connected to the top of the vibration absorption base;

The centrifugal support frame is at least partially of a hollow structure, a centrifugal driving motor is arranged in one end, far away from the vibration absorbing base, of the centrifugal support frame, an output shaft of the centrifugal driving motor is connected with a rotating table, a plurality of groups of bearing frames corresponding to a plurality of different centrifugal objects are arranged in the circumferential direction of the rotating table, each group of the plurality of groups of bearing frames comprises a plurality of bearing units, and the plurality of bearing units in the same group are uniformly distributed in the circumferential direction of the rotating table at the same preset interval angle.

2. A multi-object compatible centrifugal module according to claim 1 wherein:

The centrifugal bearing is arranged on the outer wall of the central rotating shaft of the rotating table in a fixed mode, and the centrifugal mounting disc is arranged on the outer wall of the centrifugal bearing in a fixed mode.

3. A multi-object compatible centrifugal module according to claim 2 wherein:

a bracket assembly disc is arranged between the centrifugal mounting disc and the centrifugal supporting frame, a plurality of cushioning units are arranged between the bracket assembly disc and the centrifugal mounting disc, and the cushioning units are uniformly and alternately distributed along the circumference of the centrifugal mounting disc;

The detachable fixed connection of support assembly dish is in the top of centrifugal support frame, a plurality of the equal fixed connection of one end of bradyseism unit is in on the support assembly dish, a plurality of the equal fixed connection of the other end of bradyseism unit is in on the centrifugal mounting dish.

4. A multi-object compatible centrifugal module according to claim 3 wherein:

The cushioning unit is made of rubber, and the hardness of the cushioning unit is not lower than Shore A50.

5. A multi-object compatible centrifugal module according to claim 1 wherein:

the vibration absorbing base is made of a nonmetallic material, and is at least one of artificial stone, natural stone, ceramics, gypsum, plastics and nonmetallic porous materials.

6. A multi-object compatible centrifugal module according to claim 1 wherein:

The multiunit bears the frame and contains the expansion consumable frame of multiunit tube type and is used for bearing the reagent pipe support of waiting the partial shipment.

7. A multi-object compatible centrifugal module according to claim 1 wherein:

the centrifugal driving motor drives the multiple groups of bearing frames to rotate at the rotation speed of 2500 rpm-5000 rpm.

8. A multi-object compatible centrifugal module according to claim 1 wherein:

the centrifugal module further includes a centrifugal angle restricting unit for defining any inclination angle of the plurality of carrying units during centrifugal rotation.

9. A multi-object compatible centrifugal module according to claim 1 wherein:

the centrifugal module further comprises a centrifugal chamber with an electric opening and closing cover plate, and the rotary table and the plurality of groups of bearing frames are arranged in the centrifugal chamber.

10. An automated processing module utilizing a compatible multi-object centrifugation module according to any one of claims 1 to 9, characterized in that:

The processing module comprises a first transfer assembly and a second transfer assembly, wherein the first transfer assembly is provided with a first transfer unit and a first span beam, the first transfer unit is arranged on the first span beam and can be driven to move along X, Y and Z axes, the second transfer assembly is provided with a second transfer unit and a second span beam, the second transfer unit is arranged on the second span beam, the movement stroke of the first span beam at least partially overlaps with the movement stroke of the second span beam, the first transfer assembly can transfer a first centrifugal object reagent tube into one group of bearing frames of the centrifugal module in a first time period, and the second transfer assembly can transfer a second type of centrifugal object into the other group of bearing frames of the centrifugal module in a second time period which is different from the first time period.