CN118177796A - Pharyngeal blood oxygen saturation monitoring device - Google Patents

Pharyngeal blood oxygen saturation monitoring device Download PDF

Info

Publication number
CN118177796A
CN118177796A CN202410316273.0A CN202410316273A CN118177796A CN 118177796 A CN118177796 A CN 118177796A CN 202410316273 A CN202410316273 A CN 202410316273A CN 118177796 A CN118177796 A CN 118177796A
Authority
CN
China
Prior art keywords
pharyngeal
patient
blood oxygen
oxygen saturation
flange
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202410316273.0A
Other languages
Chinese (zh)
Inventor
陆彦顼
彭倩
彭程
谢黎
姚辉
宋佳雪
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Central South University
Original Assignee
Central South University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Central South University filed Critical Central South University
Priority to CN202410316273.0A priority Critical patent/CN118177796A/en
Publication of CN118177796A publication Critical patent/CN118177796A/en
Pending legal-status Critical Current

Links

Landscapes

  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

The invention relates to the technical field of blood oxygen saturation, in particular to a pharyngeal blood oxygen saturation monitoring device which comprises an operation assembly and a flange, wherein the operation assembly comprises a display screen positioned at one side of the flange, and a connecting hole is formed in the front side of the flange. The invention has the advantages of accurate monitoring and being beneficial to finding out insufficient blood perfusion of shock patients in advance. In the actual use process, through the cooperation of operation subassembly, can provide real-time blood oxygen saturation data to can present its trend of variation, medical personnel can in time monitor patient oxygenation state. The invention can maintain the unobstructed airway of the oropharynx part of the patient, ensure the ventilation of the patient, prevent the airway from blocking and choking, provide more accurate blood oxygen saturation value, reflect the oxygenation state of the patient, and can discover the problem of insufficient oxygenation of the patient in shock severe patients as soon as possible.

Description

Pharyngeal blood oxygen saturation monitoring device
Technical Field
The invention relates to the technical field of blood oxygen saturation, in particular to a pharyngeal blood oxygen saturation monitoring device.
Background
The blood oxygen saturation monitoring device is a medical device for monitoring the ratio of human oxyhemoglobin to total hemoglobin. The devices are widely applied to clinical and household environments, and can help medical staff to know the blood oxygen condition of patients and perform timely intervention and treatment. Currently, monitoring blood oxygen saturation (SpO 2) of a shock patient is a challenge, because low perfusion greatly affects the accuracy of blood oxygen saturation monitoring of peripheral conventional parts such as fingers, toes, earlobes and the like, blood perfusion of the shock patient is reduced, skin temperature is low, spO 2 is often not measured to be a value or lower, so arterial oxygen saturation (SaO 2) is used as an alternative method to obtain more accurate measurement results, but frequent blood sampling increases pain of the patient, workload of medical staff and various complications such as vascular injury, thrombosis and the like, and therefore, selecting a part where blood flows are sufficiently perfused to improve the accuracy of monitoring SpO 2 of the shock patient is critical to the resolution of seconds of a patient suffering from a critical gram, and the pain of the patient is an important problem to be solved by clinical medical staff.
The blood oxygen saturation monitoring device disclosed by publication No. CN210408436U has the beneficial effects that: the left finger ring and the right finger ring are hollow structures, windows are formed in the inner side surfaces of the left finger ring and the right finger ring, the light emitter and the photoelectric receiver are oppositely arranged, the light emitter and the photoelectric receiver are embedded in the windows, the probe host is electrically connected with the light emitter and the photoelectric receiver respectively, the adjusting mechanism comprises an adjusting screw rod, a worm, a first turbine and a second turbine, the adjusting screw rod is arranged on the probe host, the worm is sleeved on the adjusting screw rod and meshed with the first turbine, the first turbine is fixedly connected with the right finger ring and meshed with the second turbine, the second turbine is fixedly connected with the left finger ring, the size of a finger storage space can be adjusted, slipping is not easy, the comfort level of a wearer can be improved, but the blood oxygen saturation monitoring device is used for monitoring fingers, relatively tight fitting is needed, the circulation dynamics state of a patient suffering from the huo is easy to be unstable, the accuracy of the monitoring device is affected by the conditions of reduced blood flow, insufficient perfusion and the like, the error is increased, the monitored SpO2 value and the actual blood oxygen saturation level are easy to deviate, especially in the case of hypotension and the low blood oxygen saturation state, the low oxygen saturation state is easy to be reflected, the oxygen saturation level cannot be timely displayed, and the oxygen saturation cannot be timely and cannot be timely displayed after the oxygen saturation state is easily changed.
Therefore, there is an urgent need for a pharyngeal oxyhemoglobin saturation monitoring apparatus that addresses the above-described issues.
Disclosure of Invention
The invention aims to provide a pharyngeal oxyhemoglobin saturation monitoring device which has the advantages of accurate monitoring and contribution to finding out insufficient tissue perfusion in advance, and solves the problems that the oxyhemoglobin saturation monitoring device monitors the positions of fingers, toes and the like, needs relatively tight fitting to accurately measure oxyhemoglobin saturation, is easy to generate delayed reaction and cannot reflect the change of oxyhemoglobin state in real time.
In order to achieve the above purpose, the present invention provides the following technical solutions: the utility model provides a pharyngeal blood oxygen saturation monitoring devices, includes operation subassembly and edge of a wing, operation subassembly includes the display screen that is located edge of a wing one side, the connecting hole has been seted up to the front side of edge of a wing, the rear side of edge of a wing is provided with adjusting part.
The utility model discloses a throat bending tube, including adjusting part, including the connecting pipe of fixed connection in the edge of a wing rear side, the surface of connecting pipe is provided with electronic processing unit, three spacing hole has been seted up on the surface of connecting pipe, the inner chamber sliding connection of connecting pipe has fixed pipe, the surface swing joint of fixed pipe has the locating piece, the inner wall swing joint of locating piece and spacing hole, the one end fixedly connected with throat bending tube of fixed pipe, the one end fixedly connected with sensor of throat bending tube, the surface of throat bending tube is provided with the fluorescent tube subassembly, electronic processing unit, fluorescent tube subassembly and sensor cooperation use.
Preferably, the surface of the connecting pipe is fixedly connected with a bite-block, and the bite-block is in a curved shape.
Preferably, two symmetrically arranged grooves are formed in one side of the flange, and anti-slip pads are fixedly connected inside the grooves.
Preferably, a positioning groove is formed in the surface of the connecting pipe, and the inner wall of the positioning groove is fixedly connected with the electronic processing unit.
Preferably, the inside of connecting hole is dismantled and is connected with the connector, one side electric connection of connector has the connecting wire, the one end fixedly connected with connector of connecting wire, one side and the display screen electric connection of connector.
Preferably, the display screen is used for displaying blood oxygen saturation data of the patient and related monitoring information.
Preferably, the pharyngeal curved tube is configured to better conform to the anatomy of the pharynx when monitoring the oxygen saturation of the pharynx.
Preferably, a through hole is formed in one side of the flange, and the through hole is used for maintaining and opening the oropharyngeal airway of the patient.
A method of using a pharyngeal blood oxygen saturation monitoring device, the method comprising the steps of:
Step one: firstly, a worker presses down a positioning block to enable a fixing tube to slide in an inner cavity of a connecting tube, when the length is proper, the positioning block is locked through a limiting hole, the correct size is ensured, a patient is in a supine position, the head is slightly bent backwards, the pharynx bending tube is held, the round head part enters the oral cavity of the patient, in order to avoid injury, the arc surface of the pharynx bending tube is ensured to face upwards, the pharynx bending tube is pushed forwards along the back of the tongue, then the pharynx bending tube is slowly and gently pushed downwards until the pharynx part reaches a proper position, the positions of a lamp tube component and a sensor are confirmed to be correct, the lamp tube component and the sensor are ensured to be in tight contact with the pharynx, so that accurate readings can be obtained, and a flange is firmly fixed on the face of the patient by using a corresponding fixing belt. After insertion of the pharyngeal curved tube, the patient's respiratory condition, blood oxygen saturation and other vital signs need to be closely monitored and adjusted and managed as necessary.
Step two: the infrared light wave of the lamp tube assembly and the sensor can penetrate into blood, the intensity of the light wave can be measured, related information is transmitted to the display screen through the electronic processing unit, the blood oxygen saturation value of a patient is displayed on the display screen, and the current blood oxygen level can be known from the display screen.
Compared with the prior art, the invention has the following beneficial effects:
The invention has the advantages of accurate monitoring, being beneficial to finding out insufficient tissue perfusion in advance, and in the actual use process, the invention can provide real-time oxygenation state data through the cooperation of the operation components, can present trend change of oxygenation state, and can enable medical staff to respond to the illness state of patients rapidly by monitoring the oxygenation state of the pharyngeal in real time and monitor the effect of therapeutic measures.
The invention can maintain the unobstructed of the patient's oropharynx airway, ensure the ventilation of the patient, prevent the airway from blocking and choking, and can also provide the direct tissue oxygenation level to reflect the oxygenation state of pharyngeal tissues through the cooperation of the adjusting components. In shock severe patients, more accurate core oxygenation data can be provided, the problems of insufficient blood flow perfusion and insufficient oxygenation can be found early, medical staff is helped to intervene in time, and the functions of tissues and organs are prevented from being damaged. Compared with other monitoring modes, the pharyngeal oxyhemoglobin saturation monitoring device can monitor pharyngeal oxyhemoglobin saturation more directly, is suitable for a patient with Hu Ke severe who needs to monitor the condition of patient's oxyhemoglobin closely, can intuitively display the value of the oxyhemoglobin saturation of the patient, is convenient for medical staff to observe and evaluate in real time, and solves the problems that the oxyhemoglobin saturation monitoring device monitors the positions of fingers, toes and the like, needs relatively tight fit to accurately measure oxyhemoglobin saturation, is easy to delay reaction and cannot reflect the change of the oxyhemoglobin state in real time.
Drawings
FIG. 1 is a schematic perspective view of the present invention;
FIG. 2 is a schematic perspective view of a monitoring structure according to the present invention;
FIG. 3 is a schematic view of a split perspective structure of an adjusting assembly according to the present invention;
fig. 4 is a schematic perspective view of the flange, the connecting hole and the anti-slip pad according to the present invention.
In the figure: 1. an operating assembly; 11. a display screen; 12. a connection hole; 13. an anti-slip pad; 14. a connector; 15. a connecting wire; 16. a connector; 2. an adjustment assembly; 21. a connecting pipe; 22. a limiting hole; 23. a positioning block; 24. a fixed tube; 25. a pharyngeal curved tube; 26. a lamp tube assembly; 27. a sensor; 28. an electronic processing unit; 29. a bite-block; 3. a positioning groove; 4. flanges.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Referring to fig. 1-4, a pharyngeal oxyhemoglobin saturation monitoring device includes an operation assembly 1 and a flange 4, wherein a through hole is formed in one side of the flange 4, the through hole is used for maintaining and opening an oropharyngeal airway of a patient, the oropharyngeal airway of the patient can be effectively kept clear through the arrangement of the through hole on one side of the flange 4, the condition of hypoxia caused by insufficient oxygen of the patient is reduced, the operation assembly 1 includes a display screen 11 positioned on one side of the flange 4, the display screen 11 is used for displaying oxyhemoglobin saturation data and related monitoring information of the patient, the oxyhemoglobin saturation value of the patient can be intuitively displayed through the arrangement of the display screen 11, the oxyhemoglobin saturation value is expressed in a percentage form, the oxygenic state of the patient can be reflected, a connecting hole 12 is formed in the front side of the flange 4, and an adjusting assembly 2 is arranged on the rear side of the flange 4.
The adjusting component 2 comprises a connecting pipe 21 fixedly connected with the rear side of the flange 4, an electronic processing unit 28 is arranged on the surface of the connecting pipe 21, three limiting holes 22 are formed on the surface of the connecting pipe 21, a fixing pipe 24 is slidably connected with an inner cavity of the connecting pipe 21, a positioning block 23 is movably connected with the surface of the fixing pipe 24, the positioning block 23 is movably connected with the inner wall of the limiting hole 22, one end of the fixing pipe 24 is fixedly connected with a pharynx bending pipe 25, the pharynx bending pipe 25 is used for being more suitable for the anatomical structure of the pharynx when monitoring the oxygen saturation of the pharynx, the pharynx bending pipe 25 can be more smoothly passed through the pharynx and fixed at a proper position, thereby improve the comfort level that the patient used, the one end fixedly connected with sensor 27 of throat crooked pipe 25, the surface of throat crooked pipe 25 is provided with fluorescent tube subassembly 26, electronic processing unit 28, fluorescent tube subassembly 26 and sensor 27 cooperation use, fluorescent tube subassembly 26 can send red light and infrared light, when red light and infrared light are shone the region that contains oxyhemoglobin, like fingertip or earlobe, oxyhemoglobin can absorb more red light, also can absorb more infrared light simultaneously, on the contrary, the hemoglobin that does not combine oxygen (deoxyhemoglobin) can have stronger absorption to infrared light, but the absorption to red light is weaker. Thus, by measuring the transmittance of these two lights at different wavelengths, the blood oxygen saturation can be calculated, and the photosensor in sensor 27 can transmit illumination data to electronic processing unit 28, which electronic processing unit 28 converts these data into blood oxygen saturation values via built-in calculation circuitry.
In this embodiment, the bite block 29 is fixedly connected to the surface of the connecting tube 21, the bite block 29 is curved, and by setting the bite block 29, better stability can be provided, and the connecting tube 21 is fixed between the oral cavity and the teeth, so as to reduce the risk of movement and falling in the oral cavity.
In this embodiment, two recesses that are the symmetry setting have been seted up to one side of edge of a wing 4, and the inside fixedly connected with slipmat 13 of recess is through the setting of slipmat 13, makes things convenient for the sticky tape, and is fixed more firm, is difficult for droing, reduces the discomfort and the misinsertion that the aversion leads to.
In this embodiment, the positioning groove 3 is formed on the surface of the connecting tube 21, the inner wall of the positioning groove 3 is fixedly connected with the electronic processing unit 28, and by setting the positioning groove 3, it is ensured that the electronic processing unit 28 maintains the correct position and function, and a more accurate and reliable blood oxygen saturation measurement result can be provided.
In this embodiment, the inside of connecting hole 12 is detachably connected with connector 14, and one side electric connection of connector 14 has connecting wire 15, and the one end fixedly connected with connector 16 of connecting wire 15, one side and the display screen 11 electric connection of connector 16 use through the cooperation of connector 14, connecting wire 15 and connector 16 for monitoring devices installs and dismantles with display screen 11 more easily, can improve availability factor, reduces operating time.
A method of using a pharyngeal blood oxygen saturation monitoring device, the method comprising the steps of:
Step one: firstly, a worker presses down the positioning block 23 to enable the fixing tube 24 to slide in the inner cavity of the connecting tube 21, when the length is proper, the positioning block 23 is locked through the limiting hole 22 to ensure that the correct size is ensured, a patient is in a supine position, the head is slightly reclined, the pharyngeal bending tube 25 is held, the round head part enters the oral cavity of the patient, the arc surface of the pharyngeal bending tube 25 is ensured to face upwards to push the pharyngeal bending tube 25 forwards along the tongue so as to avoid injury, then the pharyngeal bending tube 25 is slowly and gently pushed downwards until the pharyngeal position reaches a proper position, the positions of the tube assembly 26 and the sensor 27 are confirmed to be correct, the tube assembly 26 and the sensor 27 are ensured to be in tight contact with the pharyngeal part, so that accurate readings are obtained, the flange 4 is firmly fixed on the face of the patient by using the corresponding fixing band, after the pharyngeal bending tube 25 is inserted, the respiration condition, the blood oxygen saturation and other vital signs of the patient are required to be closely monitored, and necessary adjustment and management are carried out according to the situation;
Step two: so that the light waves of the tube assembly 26 and the sensor 27 penetrate into the blood, the intensity of the light waves can be measured, the relevant information is transmitted to the display screen 11 by the electronic processing unit 28, and the display screen 11 displays the blood oxygen saturation value of the patient, from which the current blood oxygen level can be known.
It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (9)

1. The utility model provides a pharyngeal oxyhemoglobin saturation monitoring devices, includes running assembly (1) and edge of a wing (4), its characterized in that: the operation assembly (1) comprises a display screen (11) positioned at one side of a flange (4), a connecting hole (12) is formed in the front side of the flange (4), and an adjusting assembly (2) is arranged at the rear side of the flange (4);
The utility model provides an adjusting part (2) include fixed connection in connecting pipe (21) of edge of a wing (4) rear side, the surface of connecting pipe (21) is provided with electronic processing unit (28), three spacing hole (22) have been seted up on the surface of connecting pipe (21), the inner chamber sliding connection of connecting pipe (21) has fixed pipe (24), the surface swing joint of fixed pipe (24) has locating piece (23), the inner wall swing joint of locating piece (23) and spacing hole (22), the one end fixedly connected with pharynx crooked pipe (25) of fixed pipe (24), the one end fixedly connected with sensor (27) of pharynx crooked pipe (25), the surface of pharynx crooked pipe (25) is provided with fluorescent tube assembly (26), electronic processing unit (28), fluorescent tube assembly (26) are used with sensor (27) cooperation.
2. The pharyngeal oxyhemoglobin saturation monitoring apparatus of claim 1, wherein: the surface of the connecting pipe (21) is fixedly connected with a bite-block (29), and the bite-block (29) is in a bending shape.
3. The pharyngeal oxyhemoglobin saturation monitoring apparatus of claim 1, wherein: two symmetrically arranged grooves are formed in one side of the flange (4), and anti-slip pads (13) are fixedly connected inside the grooves.
4. The pharyngeal oxyhemoglobin saturation monitoring apparatus of claim 1, wherein: the surface of the connecting pipe (21) is provided with a positioning groove (3), and the inner wall of the positioning groove (3) is fixedly connected with the electronic processing unit (28).
5. The pharyngeal oxyhemoglobin saturation monitoring apparatus of claim 1, wherein: the connector is characterized in that a connector (14) is detachably connected to the inside of the connecting hole (12), a connecting wire (15) is electrically connected to one side of the connector (14), a connector (16) is fixedly connected to one end of the connecting wire (15), and one side of the connector (16) is electrically connected with the display screen (11).
6. The pharyngeal oxyhemoglobin saturation monitoring apparatus of claim 1, wherein: the display screen (11) is used for displaying blood oxygen saturation data of a patient and related monitoring information.
7. The pharyngeal oxyhemoglobin saturation monitoring apparatus of claim 1, wherein: the pharyngeal curved tube (25) is adapted to better conform to the anatomy of the pharynx when monitoring the oxygen saturation of the pharynx.
8. The pharyngeal oxyhemoglobin saturation monitoring apparatus of claim 1, wherein: one side of the flange (4) is provided with a through hole which is used for maintaining and opening the oropharynx airway of the patient.
9. The application method of the pharyngeal blood oxygen saturation monitoring device is characterized by comprising the following steps of: the method comprises the following steps:
Step one: firstly, a worker presses down a positioning block (23) to enable a fixing tube (24) to slide in an inner cavity of a connecting tube (21), when the length is proper, the positioning block (23) is locked through a limiting hole (22), correct size is ensured, the patient is kept clean and sterilized, the patient is in a supine position, the head is slightly leaned back, the pharyngeal curved tube (25) is held, the round head part enters the oral cavity of the patient, in order to avoid injury, the arc surface of the pharyngeal curved tube (25) is ensured to face upwards, the pharyngeal curved tube (25) is pushed forwards along the tongue, then the pharyngeal curved tube (25) is slowly and gently pushed downwards until the pharyngeal part reaches a proper position, the lamp tube assembly (26) and a sensor (27) are ensured to be in close contact with the pharyngeal part, so that accurate readings are obtained, a flange (4) is firmly fixed on the face of the patient by using a corresponding fixing band, after the pharyngeal curved tube (25) is inserted, the respiratory condition, blood oxygen saturation and other vital signs of the patient are required to be closely monitored, and adjustment and management are carried out according to the condition;
Step two: the infrared light wave of the lamp tube assembly (26) and the sensor (27) can penetrate into blood through the skin, the intensity of the light wave can be measured, related information is transmitted to the display screen (11) through the electronic processing unit (28), the blood oxygen saturation value of a patient is displayed on the display screen (11), and the current blood oxygen level can be known from the blood oxygen saturation value.
CN202410316273.0A 2024-03-19 2024-03-19 Pharyngeal blood oxygen saturation monitoring device Pending CN118177796A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202410316273.0A CN118177796A (en) 2024-03-19 2024-03-19 Pharyngeal blood oxygen saturation monitoring device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202410316273.0A CN118177796A (en) 2024-03-19 2024-03-19 Pharyngeal blood oxygen saturation monitoring device

Publications (1)

Publication Number Publication Date
CN118177796A true CN118177796A (en) 2024-06-14

Family

ID=91405606

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202410316273.0A Pending CN118177796A (en) 2024-03-19 2024-03-19 Pharyngeal blood oxygen saturation monitoring device

Country Status (1)

Country Link
CN (1) CN118177796A (en)

Similar Documents

Publication Publication Date Title
Kyriacou Pulse oximetry in the oesophagus
DeMeulenaere Pulse oximetry: uses and limitations
US10532170B2 (en) Method and system for classification of photo-plethysmographically detected respiratory effort
EP2486850B1 (en) Specially configured nasal pulse oximeter
US6529752B2 (en) Sleep disorder breathing event counter
US6909912B2 (en) Non-invasive perfusion monitor and system, specially configured oximeter probes, methods of using same, and covers for probes
US6615064B1 (en) Non-invasive blood component analyzer
AU2001236874B2 (en) Pacifier pulse oximeter sensor
US9668661B2 (en) Devices, systems and methods for plethysmographic monitoring at the nose
JP2007518480A (en) New and specially configured nasal pulse oximeter
JP2002524122A (en) Nasopharyngeal tracheal airway with reflectance pulse oximeter sensor
AU2001236874A1 (en) Pacifier pulse oximeter sensor
JP2002516689A (en) Stereo pulse oximeter
Kyriacou Direct pulse oximetry within the esophagus, on the surface of abdominal viscera, and on free flaps
Keogh et al. Recent findings in the use of reflectance oximetry: a critical review
CN118177796A (en) Pharyngeal blood oxygen saturation monitoring device
Budidha In vivo investigations of photoplethysmograms and arterial oxygen saturation from the auditory canal in conditions of compromised peripheral perfusion
Kyriacou et al. Arterial blood oxygen saturation during blood pressure cuff-induced hypoperfusion
Wong Pulse Oximetry: Technology and Clinical Uses.
Doherty The advantages of oximetry during paediatric anaesthesia
Wilson Monitors
van Oostrom et al. Civetta, Taylor, & Kirby's: Critical Care
Benni et al. “Innovations and Applications of Monitoring Oxygenation and Ventilation”(ISIAMOV), Duke University, Durham, NC, March 15–17, 2007

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination