CN118121658A - Synergistic qi and blood supplementing composition and application thereof - Google Patents
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Abstract
The invention belongs to the technical field of traditional Chinese medicine compositions, and in particular relates to a synergistic qi-tonifying qi-blood composition and application thereof, wherein the composition comprises a main formula which is composed of the following traditional Chinese medicine raw materials: indigo honeysuckle, radix codonopsis pilosulae, radix astragali, rhizoma polygonati, jujube, cortex phellodendri and white hyacinth bean. The composition has excellent effects of tonifying qi and blood.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a synergistic qi-tonifying qi-blood composition and application thereof.
Background
Qi and blood refer to two important substances in the human body in traditional Chinese medicine. Qi refers to the vital energy or vitality in the human body, and plays an important role in the process of maintaining vital activities. Blood refers to nutrients in the human body, including liquid and solid components. In the theory of traditional Chinese medicine, qi and blood are interdependent and mutually transformed, so that the normal physiological functions of human bodies are maintained together.
In traditional Chinese medicine, qi deficiency and blood deficiency are often said, namely qi and blood deficiency, and the qi deficiency and blood deficiency mainly manifests as pale complexion, dizziness, fatigue, qi deficiency and lazy speaking, etc., and the result of qi and blood deficiency can lead to viscera hypofunction and cause premature senility lesions.
The traditional Chinese medicine is as follows: qi is the general and mother of blood, and the two depend on each other and interact with each other. Qi and blood are mutually bred, and qi is the essence of a person, so that the blood circulation can be promoted, and also can be carried, so that the normal operation of the functions of all organs of a human body is promoted, otherwise, the hypofunction of the organs of the human body can be caused by the deficiency of qi and blood. The theory of traditional Chinese medicine holds that: the deficiency of qi and blood is treated by the method of supplementing; qi and blood are disturbed, so that only blood is not sufficient, and Qi is supplemented, so that root regulation and root control are needed. "
Qi and blood deficiency, weakness of limbs, soreness and weakness of waist and knees, emaciation with yellowish complexion, amnesia and insomnia, postpartum deficiency of women are common and frequent diseases in clinic, and clinical treatment is difficult; at present, more Chinese patent medicines are clinically used, but most of the curative effects are not ideal.
Disclosure of Invention
The invention aims to solve the problems of the traditional Chinese patent medicine for tonifying qi and blood, and provides a synergistic composition for tonifying qi and blood and application thereof.
In a first aspect of the present invention, a synergistic blood replenishing composition is provided, which adopts the following technical scheme:
the synergistic qi and blood replenishing composition comprises a main formula and an auxiliary formula, wherein the main formula is composed of the following traditional Chinese medicine raw materials: indigo honeysuckle, radix codonopsis pilosulae, radix astragali, rhizoma polygonati, jujube, cortex phellodendri and white hyacinth bean.
Lonicera caerulea (academic name: lonicera caerulea L. Var. Edulis Turcz. Ex Herd.) is a variety of lonicera caerulea of the genus lonicera of the family Caprifoliaceae. Fallen leaves shrubs, young branches are fluffed, old branches are brown, winter buds are forked, she Xi oval shapes, double-sided thinned and grown short bristles are formed, soft hair is arranged outside corolla, a columella is free of hair, blue is black, the columella is slightly turned on, flowering is carried out for 5-6 months, and fruiting is carried out for 8-9 months. The mountain area of the east of the great Xingan mountain of the province of Heilongjiang, china is distributed in the eastern part of Heilongjiang, inner Mongolia, north China, northwest China, sichuan and the like. Is often used on river banks, swamp shrubs or mountain forests.
Indigo fruit, bitter in taste, cold in nature, and nontoxic. Efficacy: clear heat and detoxify. For treating heat toxin, furuncle, carbuncle, erysipelas, infantile malnutrition, pemphigus.
Modern medical researches prove that the lonicera caerulea has the functions of clearing heat and detoxicating, has the anti-inflammatory and antiviral capabilities, can prevent capillary rupture, reduce blood pressure and improve the detoxication function of the liver, has the anti-tumor efficacy, can relieve uncomfortable symptoms after radiotherapy, and can slow down the reduction of the number of white blood cells after chemotherapy.
Dang Shen is sweet in flavor and neutral in nature. Has effects in invigorating spleen, replenishing qi, quenching thirst, invigorating spleen, tonifying lung, nourishing blood, and promoting salivation. Can be used for treating spleen and lung qi deficiency, anorexia, cough, asthma, deficiency of qi and blood, sallow complexion, palpitation, short breath, thirst due to body fluid deficiency, and internal heat and diabetes. Lazy speaking, weak limbs, poor appetite, qi deficiency, deficiency of both qi and fluid, deficiency of both qi and blood, and chlorosis due to blood deficiency. It is often combined with Bai Zhu, fu Ling and Bai Zhi Cao, which is a well-known prescription of Sijunzi Tang for invigorating Qi and spleen.
Bai Huang is sweet in flavor and warm in nature. Enter lung and spleen meridians. Has effects in invigorating qi, consolidating superficial resistance, promoting urination, removing toxic substances, expelling pus, healing sore, and promoting granulation. Modern medical research shows that astragalus has the functions of enhancing the immunity of organisms, protecting liver, promoting urination, resisting aging and stress, reducing blood pressure and resisting bacteria widely. Can eliminate experimental nephritis proteinuria, enhance myocardial contractility, and regulate blood sugar content. Huang Qi has the actions of tonifying Qi and promoting the production of body fluid, tonifying Qi and promoting blood production, and is often combined with other herbs to enhance the therapeutic effect.
Polygonatum sibiricum is sweet in flavor and neutral in nature. Enter spleen, lung and kidney meridians. Sweet, flat, moist and smooth, with slow action, is a tonic product for long-term administration, good at replenishing yin, moistening dryness, invigorating qi and nourishing yin. The medicinal plant has effects of invigorating spleen, moistening lung and promoting salivation. Tonifying qi and yin, strengthening spleen, moistening lung and tonifying kidney. Belongs to yin-tonifying herbs classified under deficiency-tonifying herbs. Rhizoma Polygonati can increase coronary blood flow, regulate blood lipid, reduce blood sugar, resist aging and enhance immunity. The rhizoma Polygonati crude polysaccharide has immunoregulatory effect and effect, and can protect against chemical liver injury, and has antiinflammatory and antiviral effects. In addition, it also has antibacterial, pathogenic microorganism resisting, blood pressure lowering, and hemostatic effects. It is used for treating coronary heart disease, hyperlipidemia, diabetes, leukopenia, pulmonary tuberculosis, chronic hepatitis, mental insufficiency, headache, sexual impotence, tinea, etc.
Jujube, sweet in taste and warm in nature. It enters spleen and stomach and heart meridians. It is indicated for spleen deficiency syndrome. It is sweet and warm in nature, and can tonify spleen and replenish qi, and is indicated for spleen qi deficiency, emaciation, lassitude and hypodynamia, loose stool, etc. The single use is effective. For deficiency of qi and hypodynamia, it is combined with spleen-tonifying and qi-replenishing herbs such as ren Shen and Bai Zhu.
Huang Bai, bitter and cold in flavor. Enter kidney and bladder meridians. Clearing heat and drying dampness, purging fire and removing steam, and detoxicating and treating sore. Can be used for treating damp-heat diarrhea, jaundice, dark urine, itching and leukorrhagia, heat stranguria, tinea pedis, bone steaming, night sweat, spermatorrhea, pyocutaneous disease, swelling and toxin, and eczema. Salted phellodendron bark, cortex Phellodendri, radix Phellodendri, has the effect of nourishing yin to reduce pathogenic fire. Is used for treating night sweat and bone steaming due to yin deficiency and fire excess.
White hyacinth bean is sweet in taste and slightly warm. Enters the spleen and stomach meridians. Has effects in strengthening spleen, regulating stomach, eliminating dampness, and removing summer-heat. Is used for treating diarrhea due to spleen deficiency, edema, leukorrhagia, summer-heat, damp vomiting and diarrhea, and infantile malnutrition. Strengthening spleen, eliminating dampness, regulating stomach and relieving summer heat. Can be used for treating weakness of spleen and stomach, inappetence, loose stool, diarrhea, leukorrhagia, summer-heat, damp vomiting, diarrhea, chest distress, and abdominal distention.
The main prescription of the invention is prepared from the lonicera caerulea fruit blood-replenishing qi-receiving monarch drug, the codonopsis pilosula qi-tonifying blood-nourishing drug as ministerial drug, the astragalus membranaceus and the rhizoma polygonati as adjuvant drug, the lonicera caerulea fruit and the codonopsis pilosula blood-tonifying qi-tonifying drug, the qi-generating blood-generating drug and the jujube, the phellodendron bark and the white hyacinth bean as adjuvant drug. The medicines are combined, so that the traditional Chinese medicine composition can tonify qi and blood, warm but not dry, effectively treat and adapt to various symptoms caused by sufficient qi and blood, and each traditional Chinese medicine composition can ensure respective medicine effects, supplement each other, complement each other, promote medicine effects, and reduce toxic and side effects.
Preferably, in the main prescription, the weight distribution ratio of each traditional Chinese medicine raw material is as follows: 10-20 parts of lonicera caerulea fruits, 10-15 parts of codonopsis pilosula, 5-8 parts of astragalus membranaceus, 5-8 parts of rhizoma polygonati, 1-3 parts of Chinese date, 1-3 parts of amur corktree bark and 1-2 parts of white hyacinth beans, wherein the weight parts are calculated by the dry weight of the raw material medicines.
Preferably, in the main prescription, the weight ratio of the raw materials of each traditional Chinese medicine is as follows: 18 parts of lonicera caerulea, 15 parts of codonopsis pilosula, 5 parts of astragalus membranaceus, 5 parts of rhizoma polygonati, 1-3 parts of Chinese date, 1-3 parts of amur corktree bark and 1-2 parts of white hyacinth bean, wherein the weight parts are calculated by the dry weight of the raw material medicines.
The main formula can have good treatment effect on various symptoms caused by deficiency of qi and blood, and has good effects of tonifying qi and blood, relieving fatigue and the like. Although the symptoms of qi and blood deficiency can be relieved relatively quickly, the problem can not be solved fundamentally, and the symptoms of qi and blood deficiency can recur after stopping the medicine for a period of time, so that a series of symptoms corresponding to the qi and blood deficiency appear.
Thus, the inventor groups, on the basis of the main formula, developed auxiliary formulas matched with the main formula for use, wherein the auxiliary formulas are prepared from the following traditional Chinese medicine raw materials: indigo honeysuckle, astragalus, chinese yam, jujube, wolfberry fruit and dried orange peel. The traditional Chinese medicine composition is mainly used in the early stage of symptoms with obvious qi and blood deficiency, and after the symptoms disappear, the traditional Chinese medicine composition can be basically and radically cured after being continuously used for a plurality of treatment courses by using auxiliary prescription, and the subsequent recurrence possibility is low.
In the auxiliary prescription, the lonicera caerulea fruit is taken as a blood-replenishing and qi-absorbing monarch drug, the astragalus membranaceus is taken as a ministerial drug for tonifying qi and blood, the Chinese yam and the Chinese date are taken as adjuvant drugs for assisting the lonicera caerulea fruit and the astragalus membranaceus to enrich the blood and benefit the qi, the medlar and the dried orange peel are taken as auxiliary drugs for assisting the qi, and the medicines are combined to regulate the qi movement of a human body, ensure that the qi is smooth and unblocked, prevent qi and blood deficiency caused by qi stagnation, nourish the blood, promote the generation and circulation of the blood, and fundamentally invigorate the qi and the blood.
Preferably, in the auxiliary prescription, the weight parts of the traditional Chinese medicine raw materials are as follows: 10-15 parts of lonicera caerulea, 5-10 parts of astragalus membranaceus, 5-8 parts of Chinese yam, 5-8 parts of Chinese date, 1-3 parts of medlar and 1-3 parts of dried orange peel, wherein the weight parts are calculated by the dry weight of the raw material medicines.
Preferably, in the auxiliary prescription, the weight parts of the traditional Chinese medicine raw materials are as follows: 10-15 parts of lonicera caerulea, 5-8 parts of astragalus membranaceus, 5 parts of Chinese yam, 5-8 parts of Chinese date, 1-3 parts of medlar and 1-2 parts of dried orange peel, wherein the weight parts are calculated by the dry weight of the raw material medicines.
Preferably, the main prescription consists of the following traditional Chinese medicine raw materials: 18 parts of lonicera caerulea fruits, 15 parts of codonopsis pilosula, 5 parts of astragalus membranaceus, 5 parts of rhizoma polygonati, 1-3 parts of dates, 1-3 parts of amur corktree barks and 1-2 parts of white hyacinth beans; the auxiliary prescription consists of the following traditional Chinese medicine raw materials: 10-15 parts of lonicera caerulea, 5-10 parts of astragalus membranaceus, 5-8 parts of Chinese yam, 5-8 parts of Chinese date, 1-3 parts of medlar and 1-3 parts of dried orange peel, wherein the weight parts are calculated by the dry weight of the raw material medicines.
Preferably, the above composition is in the form of a powder, granule, block, tablet, capsule, pill, liquid or paste.
In a second aspect, the invention provides the use of a composition as hereinbefore described for the manufacture of a medicament for the replenishment of qi and blood.
In a third aspect, the present invention provides a medicament for supplementing qi and blood, the active ingredient of which comprises the aforementioned composition.
Detailed Description
The invention is further illustrated by the following description of specific embodiments, which are not intended to be limiting, and various modifications or improvements can be made by those skilled in the art in light of the basic idea of the invention, but are within the scope of the invention without deviating from the basic idea of the invention.
The endpoints and any values of the ranges disclosed herein are not limited to the precise range or value, and are understood to encompass values approaching those ranges or values. For numerical ranges, one or more new numerical ranges may be found between the endpoints of each range, between the endpoint of each range and the individual point value, and between the individual point value, in combination with each other, and are to be considered as specifically disclosed herein.
Example 1
Primary formula one: 15g of lonicera caerulea fruits, 10g of codonopsis pilosula, 5g of astragalus membranaceus, 5g of rhizoma polygonati, 3g of dates, 3g of amur corktree barks and 1g of white hyacinth beans.
And a second main formula: 18g of lonicera caerulea, 12g of codonopsis pilosula, 5g of astragalus membranaceus, 5g of rhizoma polygonati, 3g of jujube, 3g of cortex phellodendri and 1g of white hyacinth bean.
And the third main formula: 18g of lonicera caerulea, 15g of codonopsis pilosula, 6g of astragalus membranaceus, 6g of rhizoma polygonati, 3g of jujube, 3g of cortex phellodendri and 2g of white hyacinth bean.
And the main formula is four: 18g of lonicera caerulea, 15g of codonopsis pilosula, 5g of astragalus membranaceus, 5g of rhizoma polygonati, 3g of jujube, 2g of cortex phellodendri and 1g of white hyacinth bean.
Control group: 10g of codonopsis pilosula, 10g of astragalus, 10g of poria cocos, 5g of liquorice, 10g of bighead atractylodes rhizome, 10g of prepared rehmannia root, 10g of Chinese angelica, 10g of szechuan lovage rhizome and 5g of white paeony root. The formula is a formula which is commonly used for tonifying qi and blood in a certain Chinese medicine department cooperated with the applicant.
The gram weights are calculated according to the dry weight of the crude drug.
The four main drugs are prepared into corresponding oral liquid according to the following method:
Decocting the corresponding medicinal materials in water for about 1 hr. Filtering to obtain filtrate, and making into corresponding oral liquid.
Example 2
Animal efficacy tests were performed on the four main subjects in example 1.
The test method comprises the following steps: taking blood deficiency mice as test subjects, taking oral liquid corresponding to the first principal prescription, the second principal prescription, the third principal prescription and the fourth principal prescription, and has effects of resisting fatigue and anoxia of the blood of the mice.
1. Effects on mouse blood
Test materials:
Selecting Kunming mice with weight of 20-25g, and keeping constant humidity (45-65%) at constant temperature (21-23deg.C) under the same feeding conditions in each feeding room with 12 hr light and shade period. After 5 days of feeding, selecting qualified weight people, and making a blood loss type blood deficiency model: each mouse is subjected to tail blood taking before experiments, hb and RBC levels are measured firstly, then tail blood is taken out by 0.5ml respectively, the animals are subjected to blood loss, and after 24 hours after blood loss, the tail blood is taken out to measure Hb and RBC, so that the hematopoietic deficiency model is determined successfully.
The test method comprises the following steps:
Mice successfully modeled as blood deficiency were selected and randomly divided into 14 groups according to body weight and sex, designated as group A1 (low dose corresponding to principal one), group A2 (medium dose corresponding to principal one), group A3 (high dose corresponding to principal one), group B1 (low dose corresponding to principal two), group B2 (medium dose corresponding to principal two), group B3 (high dose corresponding to principal two), group C1 (low dose corresponding to principal three), group C2 (medium dose corresponding to principal three), group C3 (high dose corresponding to principal three), group D1 (low dose corresponding to principal four), group D2 (medium dose corresponding to principal four), group D3 (high dose corresponding to principal four). Each group contains 5 oral liquids, and the corresponding oral liquids are fed by stomach irrigation before feeding. Blank groups were given equal volumes of fresh water. Twice daily. The administration was continued for 30 days. After 1 hour of the last administration, tail blood was taken for Hb and RBC measurement, and the average value was taken. The results are shown in Table 1.
TABLE 1 detection results of Hb and RBC in blood of mice
Through significance analysis, the low, medium and high dose groups from principal one to principal four have significant differences relative to the control group and extremely significant differences relative to the blank group.
As can be seen from the data in table 1, the four main subjects in example 1 can significantly improve the blood replenishing ability of mice, and have excellent blood replenishing effect, compared with the control group. Among them, the effect of the fourth main formula is especially good.
2. Anti-fatigue effect on mice
Test materials:
Selecting Kunming mice with weight of 20-25g, and keeping constant humidity (45-65%) at constant temperature (21-23deg.C) under the same feeding conditions in each feeding room with 12 hr light and shade period. After 5 days of feeding, 70 weight percent were selected.
The test method comprises the following steps:
The mice selected were randomly divided into 14 groups by body weight and sex, designated as group A1 (low dose corresponding to principal one), group A2 (medium dose corresponding to principal one), group A3 (high dose corresponding to principal one), group B1 (low dose corresponding to principal two), group B2 (medium dose corresponding to principal two), group B3 (high dose corresponding to principal two), group C1 (low dose corresponding to principal three), group C2 (medium dose corresponding to principal three), group C3 (high dose corresponding to principal three), group D1 (low dose corresponding to principal four), group D2 (medium dose corresponding to principal four), group D3 (high dose corresponding to principal four). Each group contains 5 oral liquids, and the corresponding oral liquids are fed by stomach irrigation before feeding. Blank groups were given equal volumes of fresh water. Twice daily. The administration was continued for 30 days. After the last administration for 1 hour, 1g of lead wire is added to the tail of the mouse, the mouse is put into a swimming pool, the water temperature is 25 ℃, the swimming time of the mouse is observed, and the nose of the mouse is immersed into the water for 10 seconds and does not float out of the water surface any more, so that the drowning index is obtained. The results are shown in Table 2 (average swimming time).
TABLE 2 test results of anti-fatigue effect of mice
Through significance analysis, the low, medium and high dose groups from principal one to principal four have significant differences relative to the control group and extremely significant differences relative to the blank group.
As can be seen from the data in table 2, the four main subjects in example 2 were able to significantly improve the anti-fatigue ability of mice relative to the control group. Wherein, the anti-fatigue effect of the fourth prescription is superior to that of the other three prescriptions.
3. Action on hypoxia tolerance of mice
Test materials:
Selecting Kunming mice with weight of 20-25g, and keeping constant humidity (45-65%) at constant temperature (21-23deg.C) under the same feeding conditions in each feeding room with 12 hr light and shade period. After 5 days of feeding, 70 weight percent were selected.
The test method comprises the following steps:
The mice selected were randomly divided into 14 groups by body weight and sex, designated as group A1 (low dose corresponding to principal one), group A2 (medium dose corresponding to principal one), group A3 (high dose corresponding to principal one), group B1 (low dose corresponding to principal two), group B2 (medium dose corresponding to principal two), group B3 (high dose corresponding to principal two), group C1 (low dose corresponding to principal three), group C2 (medium dose corresponding to principal three), group C3 (high dose corresponding to principal three), group D1 (low dose corresponding to principal four), group D2 (medium dose corresponding to principal four), group D3 (high dose corresponding to principal four). Each group contains 5 oral liquids, and the corresponding oral liquids are fed by stomach irrigation before feeding. Blank groups were given equal volumes of fresh water. Twice daily. The administration was continued for 30 days. After 1 hour of the last administration, the mice were placed in sealed bottles and observed for the time of death due to cardiac arrest caused by hypoxia. The results are shown in Table 3 (average survival time).
TABLE 3 results of mice hypoxia tolerance test
Through significance analysis, the low, medium and high dose groups from principal one to principal four have significant differences relative to the control group and extremely significant differences relative to the blank group.
As can be seen from the data in table 3, the four main subjects in example 3 were able to significantly improve the hypoxia tolerance of mice relative to the control group. Among them, the effect of the fourth main formula is particularly remarkable.
The following is an example of a treatment in a particular TCM department using the compositions of the present invention.
Example 3
Some women, 24 years old. Date of first visit: 8 months and 10 days 2015. Pale complexion, pale red tongue, fat and tender tongue, less menstruation, irregular menstruation and frequent dizziness.
A main formula: 15g of lonicera caerulea fruits, 10g of codonopsis pilosula, 6g of astragalus membranaceus, 5g of rhizoma polygonati, 3g of Chinese date, 3g of amur corktree bark and 2g of white hyacinth beans, wherein the gram weights are calculated according to the dry weight of the raw material medicines. The main formula is crushed into powder, and the powder is taken after soaking in boiled water, wherein the powder is taken 2 times a day and 4 g once. After 2 months of treatment, the symptoms of qi and blood deficiency disappear, and no obvious symptoms exist. Then, the auxiliary prescription is stabilized. The auxiliary prescription is as follows: 15g of lonicera caerulea, 10g of astragalus membranaceus, 8g of Chinese yam, 8g of Chinese date, 3g of wolfberry fruit and 1g of dried orange peel, and crushing the materials into powder, wherein the powder is taken after being soaked in boiled water for 2 times a day, and 4 g of the powder is taken once. The administration is continued for two months. Later, the patients are asked for a visit, the disease is stable, and no recurrence occurs.
Example 4
Zhu Mou, 32 years old. Date of first visit: 2017, 9 and 21. The eyes of the patients are yellow, have blood wires, and have bags, dark circles, rough skin, no luster and dry hair around the eyes.
A main formula: 18g of lonicera caerulea, 12g of codonopsis pilosula, 5g of astragalus membranaceus, 5g of rhizoma polygonati, 3g of jujube, 3g of cortex phellodendri and 1g of white hyacinth bean. Wherein the gram weights are calculated according to the dry weight of the crude drug. The main formula is crushed into powder, and the powder is taken after soaking in boiled water, wherein the powder is taken 2 times a day and 4 g once. After the Chinese medicinal composition is treated for two months, the symptoms of qi and blood deficiency disappear, and no obvious symptoms exist. Then, the auxiliary prescription is stabilized. The auxiliary prescription is as follows: 15g of lonicera caerulea, 8g of astragalus membranaceus, 8g of Chinese yam, 5g of Chinese date, 3g of wolfberry fruit and 1g of dried orange peel, and crushing the materials into powder, wherein the powder is taken after being soaked in boiled water for 2 times a day, and 4 g of the powder is taken once. The administration is continued for three months. Later, the patients are asked for a visit, the disease is stable, and no recurrence occurs.
Example 5
Liu Mou women, 41 years old. Date of first visit: 2018, 12, 25. The patient always feels the lower limbs cool all the year round, especially in winter; the cold and heat are afraid of the people than ordinary people; 2. dysmenorrhea of the last year, blood black on the first day, pain in the lower abdomen, soreness of the lower extremities, and occasional nausea. Menstrual period is also shorter than before by a few days, but is also within normal menstrual period; 3. often without spirit, the user is reluctant to play.
A main formula: 16g of lonicera caerulea, 13g of codonopsis pilosula, 6g of astragalus membranaceus, 6g of rhizoma polygonati, 3g of jujube, 3g of cortex phellodendri and 2g of white hyacinth bean. Wherein the gram weights are calculated according to the dry weight of the crude drug. The main formula is crushed into powder, and the powder is taken after soaking in boiled water, wherein the powder is taken 2 times a day and 4g once. After two months of treatment, endocrine is regulated to reach balance again. Then, the auxiliary prescription is stabilized. The auxiliary prescription is as follows: 12g of lonicera caerulea, 10g of astragalus membranaceus, 8g of Chinese yam, 5g of Chinese date, 1g of wolfberry fruit and 1g of dried orange peel, and crushing the materials into powder, wherein the powder is taken after being soaked in boiled water for 2 times a day, and 4g of the powder is taken once. The administration is continued for two months. After the back visit, the blood circulation of the patient is smooth, the essence and blood nourish the whole body, and the symptoms do not relapse.
EXAMPLE 6
To be somehow, female, 58 years old. Date of first visit: 10/07/2019. Patients often suffer from palpitation, insomnia, shortness of breath, dizziness, fatigue and cold feeling.
A main formula: 10g of lonicera caerulea fruits, 10g of codonopsis pilosula, 6g of astragalus membranaceus, 6g of rhizoma polygonati, 3g of dates, 2g of amur corktree barks and 1g of white hyacinth beans. Wherein the gram weights are calculated according to the dry weight of the crude drug. The main formula is crushed into powder, and the powder is taken after soaking in boiled water, wherein the powder is taken 2 times a day and 4 g once. After three months of treatment, the symptoms are obviously improved. The early stage is good after a half-year return visit, and the symptoms before the later stage appear slowly, and the possibility of recurrence is presumed. But subsequently does not continue to the middle hospital for further treatment due to the patient itself.
Example 7
Liu Mou, male, 46 years old. Date of first visit: 11.11.2018. Patients often feel weak, tired, short breath and shortness of breath, especially can not exert force, walk urgently and get far away, sweat easily and sound is low.
A main formula: 16g of lonicera caerulea, 13g of codonopsis pilosula, 5g of astragalus membranaceus, 5g of rhizoma polygonati, 1g of jujube, 3g of cortex phellodendri and 2g of white hyacinth bean. Wherein the gram weights are calculated according to the dry weight of the crude drug. The main formula is crushed into powder, and the powder is taken after soaking in boiled water, wherein the powder is taken 2 times a day and 4g once. After two months of treatment, endocrine is regulated to reach balance again. Then, the auxiliary prescription is stabilized. The auxiliary prescription is as follows: 12g of lonicera caerulea, 8g of astragalus membranaceus, 8g of Chinese yam, 5g of Chinese date, 3g of wolfberry fruit and 1g of dried orange peel, and crushing the materials into powder, wherein the powder is taken after being soaked in boiled water for 2 times a day, and 4g of the powder is taken once. The administration is continued for two months. After the back visit, the blood circulation of the patient is smooth, the essence and blood nourish the whole body, and the symptoms do not relapse.
Claims (10)
1. The synergistic qi and blood replenishing composition is characterized by comprising a main formula, wherein the main formula is prepared from the following traditional Chinese medicine raw materials: indigo honeysuckle, radix codonopsis pilosulae, radix astragali, rhizoma polygonati, jujube, cortex phellodendri and white hyacinth bean.
2. The synergistic qi and blood supplementing composition according to claim 1, wherein in the main formula, the weight ratio of the raw materials of all traditional Chinese medicines is as follows: 10-20 parts of lonicera caerulea fruits, 10-15 parts of codonopsis pilosula, 5-8 parts of astragalus membranaceus, 5-8 parts of rhizoma polygonati, 1-3 parts of Chinese date, 1-3 parts of amur corktree bark and 1-2 parts of white hyacinth beans, wherein the weight parts are calculated by the dry weight of the raw material medicines.
3. The synergistic qi and blood supplementing composition according to claim 1, wherein in the main formula, the weight ratio of the raw materials of all traditional Chinese medicines is as follows: 15-20 parts of lonicera caerulea, 10-15 parts of codonopsis pilosula, 5 parts of astragalus membranaceus, 5 parts of rhizoma polygonati, 1-3 parts of Chinese date, 1-3 parts of amur corktree bark and 1-2 parts of white hyacinth bean, wherein the weight parts are calculated by the dry weight of the raw material medicines.
4. The synergistic blood replenishing composition of claim 1, further comprising an auxiliary prescription, the auxiliary prescription being composed of the following traditional Chinese medicine raw materials: indigo honeysuckle, astragalus, chinese yam, jujube, wolfberry fruit and dried orange peel.
5. The synergistic qi and blood supplementing composition according to claim 4, wherein in the auxiliary prescription, the following traditional Chinese medicine raw materials are mixed in parts by weight: 10-15 parts of lonicera caerulea, 5-10 parts of astragalus membranaceus, 5-8 parts of Chinese yam, 5-8 parts of Chinese date, 1-3 parts of medlar and 1-3 parts of dried orange peel, wherein the weight parts are calculated by the dry weight of the raw material medicines.
6. The synergistic qi and blood supplementing composition according to claim 4, wherein in the auxiliary prescription, the following traditional Chinese medicine raw materials are mixed in parts by weight: 10-15 parts of lonicera caerulea, 5-8 parts of astragalus membranaceus, 5 parts of Chinese yam, 5-8 parts of Chinese date, 1-3 parts of medlar and 1-2 parts of dried orange peel, wherein the weight parts are calculated by the dry weight of the raw material medicines.
7. The synergistic blood-replenishing composition of claim 4, wherein the main formula is composed of the following Chinese medicinal materials: 15-20 parts of lonicera caerulea fruits, 10-15 parts of codonopsis pilosula, 5 parts of astragalus membranaceus, 5 parts of rhizoma polygonati, 1-3 parts of Chinese dates, 1-3 parts of amur corktree bark and 1-2 parts of white hyacinth beans; the auxiliary prescription consists of the following traditional Chinese medicine raw materials: 10-15 parts of lonicera caerulea, 5-10 parts of astragalus membranaceus, 5-8 parts of Chinese yam, 5-8 parts of Chinese date, 1-3 parts of medlar and 1-3 parts of dried orange peel, wherein the weight parts are calculated by the dry weight of the raw material medicines.
8. A synergistic aerated blood composition as claimed in claim 1, wherein the composition is in the form of a powder, granules, blocks, tablets, capsules, pills, liquids or pastes.
9. Use of a synergistic air-blood replenishing composition as claimed in any one of claims 1 to 8 for the preparation of a medicament for the purpose of air-blood replenishing.
10. A medicament for replenishing qi and blood, the active ingredient of which comprises a synergistic composition for replenishing qi and blood as claimed in any one of claims 1 to 8.
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