CN1180815C - Tumor treating medicine - Google Patents

Tumor treating medicine Download PDF

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Publication number
CN1180815C
CN1180815C CNB021103895A CN02110389A CN1180815C CN 1180815 C CN1180815 C CN 1180815C CN B021103895 A CNB021103895 A CN B021103895A CN 02110389 A CN02110389 A CN 02110389A CN 1180815 C CN1180815 C CN 1180815C
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medicine
treating
phymatosis
blood
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CN1383856A (en
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宫相东
于香丽
于玺长
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Abstract

The present invention discloses a medicine for treating phymatosis, which belongs to the technical field of traditional Chinese medicine. The medicine for treating phymatosis is prepared from the following crude drugs by weight: 30 to 50 portions of wild lily, 50 to 100 portions of oldenlandia diffusa, 30 to 50 portions of barbed skullcap herb, 20 to 50 portions of Chinese lobelia, 10 to 20 portions of snakegourd root, 6 to 15 portions of dried leech, 1 to 3 portions of moschus, 1 to 3 portions of bezoar, 10 to 20 portions of pangolin scale, 6 to 12 portions of notoginseng, 10 to 15 portions of edible tulip, 10 to 20 portions of Polystictus versicolor (L.) Fr., 10 to 20 portions of dutchmanspipe root, 6 to 12 portions of stiff silkworm, 10 to 16 portions of tuckahoe, 6 to 12 portions of mastix, 10 to 15 portions of myrrh and 30 to 50 portions of honeysuckle flower, which are processed into pills or tablets. The medicine for treating phymatosis has the advantages of reasonable prescription and capability of concurrently treating benign tumors and malignant tumors, and can directly inhibit or kill tumor cells and enhance reticulate endothelial cells. In addition, the medicine for treating phymatosis has strong antitumor activity, contains multiple cell protoplasm substances, has very strong affinity with the sulfhydryl group of cellular enzyme protein, and can inhibit the oxidation process of tummor cells. Therefore, the medicine for treating phymatosis is an ideal traditional Chinese medicine for treating phymatosis at present.

Description

A kind of medicine for the treatment of oncosis
Technical field
A kind of medicine for the treatment of oncosis that the present invention relates to belongs to the Chinese medicine technical field, is a kind of Chinese medicine for the treatment of benign tumor and malignant neoplastic disease specifically.
Background technology
Tumor is the prostatitis that a kind of common but severe threatens the disease, particularly malignant tumor of people's life and health to occupy the human diseases mortality rate.Modern doctor trained in Western medicine adopts the method for excision to treat various tumors usually, and this method causes great misery and heavier financial burden to patient, and is comparatively obvious for carcinoid elimination effect.For malignant tumor, in case find then generally be in middle and advanced stage, operative treatment is not a kind of best approach, although because excised focus for the middle and advanced stage cancerous protuberance, but the outer migration cancerous cell of focus is performed the operation simultaneously and the huge wound of human body has also been quickened the transfer of cancerous cell still surviving, duplicating and shift; Generally will cooperate radiotherapy or change to control after the operation, this chemicotherapy has great lethal effect to the normal human cell, greatly reduces the immunocompetence of human body self.Motherland's traditional medicine thinks, the generation of tumor (no matter optimum or pernicious) is all relevant with the six evil invasion and attack, and every human body is invaded by exopathogen, can both influence function, hinders QI-blood circulation, causes qi depression to blood stasis, and the phlegm-damp cohesion is of a specified duration and be tumor.Motherland's successive dynasties traditional Chinese medical science always with tumor treatment as a main direction, but effect is not very good always.
Summary of the invention
Purpose of the present invention is intended to improve above-mentioned deficiency, provides a kind of evident in efficacy, short treating period, can contain the growth of tumor cell effectively so kill tumor cell, taking convenience, can alleviate the Chinese medicine of patient suffering's treatment oncosis.
In order to achieve the above object, the principles of formulating prescriptions of the present invention: blood circulation promoting and blood stasis dispelling, anti-inflammatory analgetic, heat-clearing and toxic substances removing, enhance immunity ability.
Medicament composing prescription of the present invention is as follows, and in weight portion, it is with Herba Crotalariae sessiliflorae 30-50 part, Herba Hedyotidis Diffusae 50-100 part; Herba Scutellariae Barbatae 30-50 part, Herba Lobeliae Chinensis 20-50 part, Radix Trichosanthis 10-20 part, Hirudo 6-15 part; Moschus 1-3 part, Calculus Bovis 1-3 part, Squama Manis 10-20 part, Radix Notoginseng 6-12 part; Pseudobulbus cremastrae seu pleiones 10-15 part, Coriolous Dersicolor (Fr.) Quel 10-20 part, Radix Aristolochiae 10-20 part; Bombyx Batryticatus 6-12 part, Poria 10-16 part, Olibanum 6-12 part; Myrrha 10-15 part, Flos Lonicerae 30-50 part is by being processed into pill or tablet forms.
The Herba Crotalariae sessiliflorae sweet in the mouth is cold in nature poisonous.The effect that heat clearing away, dampness removing, detoxifcation are arranged.Herba Crotalariae sessiliflorae contains 7 kinds of alkaloids, and wherein content is more Herba Crotalariae sessiliflorae second element, Herba Crotalariae sessiliflorae third element, crotaline (monocrotaline), and crotaline content is about 0.02% in herb, be about 0.4% in seed.Monocrotaline all has certain inhibitory action to murine sarcoma-180, leukemia L615, W-256-256 etc., and is wherein especially obvious to watt gram cancer-256 curative effect, is 54-75% to the S-37 suppression ratio.The Herba Crotalariae sessiliflorae alkaloid is a double pyrrolizidine pyridine class, and its antitumaous effect is similar to alkylating agent.Monocrotaline has lasting and significant hypotensive effect to the anesthesia Canis familiaris L., and can suppress extrasomatic rabbit heart, and smooth muscle is had excitation.Monocrotaline toxicity is very big, rat skin lower injection median lethal dose(LD 50) 134 ± 11,6mg/kg, animal performance systemic bleeding, the obvious cloudy swelling hyperemia of liver.
Herba Hedyotidis Diffusae is cold in nature, mildly bitter flavor, sweet.Return stomach, large intestine, small intestine meridian.Have heat-clearing and toxic substances removing, effect that dampness removing is treating stranguria.The Herba Hedyotidis Diffusae hardship is let out cold clear, and stronger heat-clearing and toxic substances removing eliminating carbuncle effect is arranged, and is used for all cards of pyretic toxicity.The Herba Hedyotidis Diffusae herb contains rubichloric acid., rubichloric acid. acid, the acid of deacetylate rubichloric acid., Herba Paederiae time glycoside, Herba Paederiae time glycoside methyl ester, Folium Vaccinii vitis-idaeae branch, cupreol, oleanolic acid, P-coumaric acid etc.Herba Hedyotidis Diffusae high concentration water decoct has certain inhibitory action to the growth of bacillus pyocyaneus, Bacillus typhi and Bacillus proteus.This product has antiinflammatory, antitumor action; Can strengthen leukocytic phagocytic function; Also have calmness, analgesia and syngignoscism.The introduction of modern useful Herba Hedyotidis Diffusae and Rhizoma Imperatae compatibility treatment gastric cancer.
Herba Scutellariae Barbatae acrid in the mouth, hardship, cold in nature.Return liver, kidney, lung meridian.Heat-clearing and toxic substances removing is arranged, diuresis, the effect of blood stasis dispelling.The bitter remittance of this product trembled with fear clearly, and heat-clearing and toxic substances removing, diuresis are preferably arranged, and all cards of all pyretic toxicity, dysuria are all used.Hold concurrently dissipating blood stasis hemostasis of acrid in the mouth, traumatic injury is also used.The Herba Scutellariae Barbatae herb contains carthamin, isocarthamidin, high mountain baicalin, high mountain baicalin, stearic acid, cupreol, alkaloid, polysaccharide etc.50% Herba Scutellariae Barbatae decoct has inhibitory action to staphylococcus aureus, shigella flexneri, Bacillus typhi, bacillus pyocyaneus, escherichia coli etc.Herba Scutellariae Barbatae also has antitumor action, and this product also has diuresis.Modern times are also treated early stage pain in the lung, hepatocarcinoma, rectum carbuncle with the Herba Hedyotidis Diffusae compatibility.Also effective in cure to cirrhotic ascites, ovarian tumor, nasopharyngeal carcinoma simultaneously.
The Herba Lobeliae Chinensis acrid in the mouth is flat, GUIXIN small intestinal, lung meridian.Effect with heat-clearing and toxic substances removing, inducing diuresis to remove edema.This product has the merit of heat-clearing and toxic substances removing, and all cards of all pyretic toxicity all can be used; Again can inducing diuresis to remove edema, be used for abdominal distention edema, dysuria etc.The Herba Scutellariae Barbatae herb contains antabac, lobelanine, isolobelanine, flavonoid glycoside, Saponin, aminoacid, polysaccharide, P-hydroxybenzoic acid, Fumaric acid, succinic acid etc.Rhizome contains lobelinin.The Herba Lobeliae Chinensis decoct all has inhibitory action to staphylococcus aureus, escherichia coli, common pathogenic fungus.This product has venom, antitumor action.Compatibilities such as modern times and Herba Scutellariae Barbatae are used for the treatment of hepatocarcinoma.
Radix Trichosanthis sweet in the mouth, little hardship, cold nature attaches to the lung and stomach meridians.Effect with clearing away heat and promoting production of body fluid, detumescence and apocenosis.The bitter sweet and Ji of this product can be hot and suffocating clearly, lets out stomach-fire, lung moistening gold, grows body fluid.This product is gone into blood system, and rotten, tissue regeneration promoting meat are tied, gone to dislike to energy subduing inflammation, the poison that relieves inflammation or internal heat, dissipating blood stasis.Fire-toxin pents up and cause carbuncle sore tumefacting virus person, the eliminating fire and detoxication of using, detumescence and apocenosis.Join Flos Lonicerae, Squama Manis etc. and can control sore and toxic.Radix Trichosanthis contains several amino acids such as trichosanthin, THFPS, beta galactoside enzyme, carubinose glycoside enzyme, citrulline, alanine, still contains Palmic acid, d-chondrillasterol, Saponin and volume starch.Trichosanthin can cause miscarriage, antiearly pregnancy, antitumor is arranged and regulate the effect of immunologic function; Again can antibiotic, antiviral, HIV (human immunodeficiency virus) there is inhibitory action.The movable side effect such as unfavorable of heating, headache, pharyngalgia, arthralgia, neck can appear in a few patients injection trichosanthin preparation after 6-8 hour, erythra, medicine-feeding part congestion and swelling pain, total white blood cells raise part or general reactions such as (more than the 10000/mm3) also can occur.
Hirudo salty in the mouth bitterness is flat, returns Liver Channel.Effect with removing blood stasis eliminating mass.The Hirudo saline taste is walked the blood hardship and can be fallen and let out, and goes into the Liver Channel blood system, is the product of removing blood stasis eliminating mass.Be applicable to the heavily card of amenorrhea due to stagnation of blood, lump in the abdomen, traumatic injury, swelling and pain due to blood stasis.Hirudo also is used for the treatment of thrombophlebitis, thrombosis closes cold vasculitis, liver cirrhosis, digestive tract tumor etc.Hirudo contains several amino acids, and wherein glutamic acid, aspartic acid, leucine, lysine and valine content are higher; Also contain protein, heparin, antithrombase etc.; Still contain multiple elements such as sodium, potassium, calcium, magnesium, ferrum, manganese, zinc.Contain a kind of antithrombase hirudin in the fresh Hirudo saliva.Hirudin is its anticoagulation and antithrombotic main effective ingredient.Hirudin also has the thrombus effect.Hirudo have tangible diuresis.This product also has antitumaous effect.
The Moschus acrid in the mouth is warm in nature, GUIXIN, spleen channel.The refreshment of having one's ideas straightened out is arranged, promoting blood circulation to remove blood stasis, pain relieving, oxytocic effect.The hot temperature of loosing of Moschus is logical, QI exhaustion perfume (or spice), the property of walking to scurry is very strong, go into the heart have one's ideas straightened out logically close, the refreshment analepsia, be best suited for the card that key closes coma.And can lead to the unfavorable of all keys, open the meridians heap soil or fertilizer over and around the roots and hold back, interior deep marrow, outer thorough fur is joined Myrrha, Olibanum etc. and be can be used for controlling sore swollen toxin.Moschus contains macrocyclic compound, as muscone, normuscone, sound alcohol etc., steroid, long-chain compound; Also contain protein, aminoacid, allantoin, protein kinase activator and inorganic constituents potassium, sodium, calcium, magnesium, ferrum, sulfate, phosphate, carbonate etc.Moschus has excitation to the central nervous system, and can strengthen central nervous system's hypoxia-bearing capability has analgesic activity.Significant antiinflammatory action is arranged.Moschus uses the excessive acute renal failure that causes.Orally the laryngeal edema may be caused, and anaphylaxis glycosuria disease may be caused.
The Calculus Bovis sweet in the mouth is cool in nature, GUIXIN, Liver Channel.Relieving spasm by subduing liver-wind is arranged, eliminate the phlegm have one's ideas straightened out, the effect of heat-clearing and toxic substances removing.This product energy pathogenic fire purging poison, clearing away heart-fire, row knot stagnate, subduing inflammation, are the good merchantable brand of clearing heart fire detoxifcation treatment skin ulcer.Breast carcinoma, carbuncle, treatment poison etc. due to the phlegm and qi stasis stagnate in order to disappear that it is long-pending to attack, compatibilities such as normal and Moschus, Olibanum, Myrrha.Modern times are useful on multiple malignant tumor such as treatment esophageal carcinoma, gastric cancer, cervical cancer, breast carcinoma.Calculus Bovis contains bilirubin, biliverdin, cholic acid, deoxycholic acid, lithocholic acid, steroid cholic acid, fatty acid, mucin, peptide class; Also contain several amino acids such as taurine, glycine; Still contain multiple inorganic elementss such as potassium, sodium, calcium.Calculus Bovis has calmness, convulsion, analgesic, analgesic activity, also has antiinflammatory, antiallergic, antitussive, eliminates the phlegm, relievings asthma, protects the liver, effects such as function of gallbladder promoting, spasmolytic.The artificial Calculus Bovis has inhibitory action to staphylococcus aureus, hepatitis virus, encephalitis b virus, also has antitumor, radioprotective, resisting fatigue, Detoxication.
Squama Manis salty in the mouth cold nature is returned liver, stomach warp.Activating blood circulation and dissipating blood stasis is arranged, the effect of the stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis.This product acrid in the mouth is cold in nature, and the gas raw meat is walked to scurry, and no network is unlikely, can make the drug effect whole body of leading to, can the eliminating carbuncle cellulitis, treat anal fistula, evacuation of pus blood, change slough.All carbuncle and ulcer toxic swellings, acute mastitis are treated poison, attached bone carbuncle of yin nature, anal fistula anal abscess, all available it.But from the beginning of person's reducing swelling and alleviating pain, short its internal diabetes; Routed person's energy evacuation of pus corruption, short its early held back.Real in controlling the key medicine of skin ulcer.It is 26 and 29 two aliphatic amides, ring (L-seryl-L-tyrosyl) dipeptides, ring (D-seryl L-tyrosyl) dipeptides that Squama Manis contains stearic acid, cholesterol, two tridecanoyl butylamine, carbon number.Contain elements such as Zn, Na, Ti, Ca, Pb, Si, P, Fe, Mn, Cr, Mg, Cu, V, B, Al, Mo, Sn again; Still contain 16 seed amino acids such as aspartic acid, threonine, serine, glutamic acid, glycine, alanine, cysteine, valine, methionine, isoleucine, leucine, tyrosine, arginine, lysine, phenylalanine, proline; Other contains water solublity alkaloid and volatilization wet goods.100% Squama Manis water extract-alcohol precipitation liquid can significantly increase the dog femoral artery blood flow, reduces Peripheral resistance, and blood vessel is had direct dilating effect.Lumbar injection 10% decocting liquid has obvious prolongation mice and rat clotting time, and the effect of blood viscosity lowering all has significant anti-Fructus Crotonis induced mice ear inflammatory effect after the water extract of Squama Manis, alcohol extract gavage.Contained ring (L-seryl-L-tyrosyl) dipeptides, ring (D-seryl L-tyrosyl) dipeptides in the Squama Manis, the tolerance of the mice normobaric hypoxia that is improved.
Radix Notoginseng sweet in the mouth, little hardship, warm in nature; Return liver, stomach warp.The effect that hemostasia and dissipation blood stasis, subduing swelling and relieving pain are arranged.This product hardship lets out that row stagnates, blood-activating analgetic, temperature three-way meridian, dissipating blood stasis for subsidence of swelling, for noxious dampness stop up stagnate due to unknown carbuncle, gnawing pains take no rest person, the eliminating carbuncle eliminating stagnation of using.Radix Notoginseng contain the ginsenoside-Rb1 ,-Rb2 ,-Rc ,-Rd ,-Re ,-Rf ,-Rg ,-Rg1 ,-Rg2 ,-Rh etc., but based on the ginsenoside-Rb1 ,-Rg1; Contain Radix Notoginseng flavone A, Radix Notoginseng flavone B, Radix Notoginseng propylhomoserin etc. in addition.Radix Notoginseng can promote coagulation process, and stronger anastalsis is arranged, and the hemostasis effective ingredient is the Radix Notoginseng propylhomoserin.Radix Notoginseng all has obvious inhibitory action to multiple acute and chronic inflammatory model, and effective content of anti inflammation is a Saponin, based on ginseng diol saponin.Radix Notoginseng has definite analgesic activity, and analgesic effective component is mainly with ginseng diol saponin.Arasaponin has stronger anti-tumor activity.Arasaponin protects the liver in addition, antibacterial action.
The little suffering of Pseudobulbus cremastrae seu pleiones sweet in the mouth, cool in nature, return liver, spleen channel.The effect that heat-clearing and toxic substances removing, dissipating phlegm and resolving masses are arranged.The Pseudobulbus cremastrae seu pleiones acrid in the mouth can loose, and is cold with heat clearing away, and the effect of tool heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation is used for pyretic toxicity Zhuge Liang card and disease trace mass in the abdomen.Modern times have and compatible treatment cyclomastopathy persons such as Herba Scutellariae Barbatae.The contained colchicine of Pseudobulbus cremastrae seu pleiones can prevent intestinal adhesion in addition; Treatment behcets disease, prolapse of intervertebral disc disease and multiple malignant tumor.The mucous matter of Pseudobulbus cremastrae seu pleiones, farrerol I, farrerol II and colchicine.Colchicine has significant protection liver and antiinflammatory, gout, antitumor action.Farrerol II has hypotensive effect.Pseudobulbus cremastrae seu pleiones can cause gastrointestinal reaction, alopecia, slight bone marrow depression, leukopenia and polyneuritis etc. at amount clothes of a specified duration.
Coriolous Dersicolor (Fr.) Quel sweet in the mouth, property are put down.Return lung, the heart, spleen channel.The tonification of Ganoderma sugariness, the property of medicine are gentle, the biochemical QI and blood of spleen master, and lung governing qi, heart master blood, so the strengthening the spleen and stomach replenishing QI and blood, QI and blood is filled then the mind and is pacified.All weakness of the spleen and stomach, deficiency of both QI and blood, the heart lose that it is supported, prolonged illness asthenia person is all available.Replenishing QI and blood, tranquilizing mind, strengthening the spleen and stomach.Coriolous Dersicolor (Fr.) Quel contains the chemical constituent of multiple complexity, and triterpenes is arranged, alkaloids, ergosterol, Ergota steroid-7,22-diene-3 β-steroid classes such as alcohol, lactone, ucleosides, the coumarin glycoside, volatile oil, polypeptide amino acid class, resin, oils and fats, organic acid such as benzoic acid, stearic acid, multiple enzymes such as fungus lysozyme, acid protease, trypsin, amylase; Inorganic elements and polysaccharides such as calcic, magnesium, manganese again; Still contain from sporophore and separate the water-soluble glucan obtain and separate the ganoderan that obtains from mycelium.The Coriolous Dersicolor (Fr.) Quel pivot nerve that liquidates has analgesia and anti-electrofit effect, and heart is had comparatively comprehensively protection, improves the supply of multiple animal cardiac muscle blood oxygen, strengthens myocardial contraction.Reduce the consumption of cardiac energy, improve hypoxia-bearing capability.Coriolous Dersicolor (Fr.) Quel makes immunostimulant; can protect the liver; alleviate the liver fat degeneration, and antioxidation, slow down aging, radioprotective, antiviral, antiulcer, antiinflammatory, anti-damage are arranged, suppress the muscle cell membrane lipid peroxidation that reactive oxygen free radical causes and myocyte's damage is had protective effect.Krestin has blood sugar lowering, cholesterol reducing and antitumor, effects such as anti-mutation.
Radix Aristolochiae acrid in the mouth, hardship, cold in nature, return liver, stomach warp.Promoting the circulation of QI to relieve pain are arranged, detoxify, ward off dirty, repercussive effect.The Radix Aristolochiae hardship is let out, heat clearing away cold in nature, and the gas of benefaction liver stomach and pain relieving is used for stagnation of liver-QI and stomach-QI pain, the hot person that holds concurrently is suitable especially.Radix Aristolochiae contains Aristolochic Acid, debilic acid, magnoline, allantoin and volatile oil.Contain aristolone and isoaristolone etc. in the oil, this product still contains aristolenone, aristolochic acid A, Aristolochic acid B C, 7-hydroxyl aristolochic acid A, Aristolochic Acid C-6-methyl ether, aristolochic acid A-methyl ester, Aristolochic Acid D-6-methyl ether etc.Allantois have the effect that promotes muscle growth, and the Radix Aristolochiae decoct has calmness, analgesia and antiinflammatory action.But the ethanol extraction enhancing body's immunological function of Radix Aristolochiae.Aristolochic Acid has inhibitory action to animal tumor.The Radix Aristolochiae total alkaloids has in various degree bacteriostasis to various pathogens, and can strengthen the activate the phagocytic capacity of peritoneal macrophage.
Bombyx Batryticatus salty in the mouth, suffering, property is flat, returns lung, liver, stomach warp.The effect that relieving spasm by subduing liver-wind, detoxicating and resolving stagnation of pathogens are arranged.This product can the suitable stagnation of QI, expectorant saliva is swollen through expel stagnation, the dissipating blood stasis resistance, attacks and cuts mass in the abdomen when gathering machine, the pathogenic heat of dispelling, removes noxious dampness and then treats carbuncle.This product contains protein, ammonium oxalate, several amino acids, as lysine, leucine, aspartic acid etc.; Also contain multiple inorganic elements such as magnesium, calcium, zinc etc.; Still contain abnormal active stimulin ecdysterone, 3-hydroxyl cynruin, 6-N hydroxyethyl adenine etc.The contained ammonium oxalate of Bombyx Batryticatus has anticonvulsant action.The Bombyx Batryticatus extracting solution has calmness, anticoagulation and hypoglycemic activity.Bombyx Batryticatus has more weak inhibitory action to staphylococcus aureus, escherichia coli, bacillus pyocyaneus etc.
The Poria slightly sweet flavor is flat, goes into cardiopulmonary, spleen, kidney channel.Have in promoting diuresis to eliminate damp pathogen, the spleen invigorating benefit, mind tranquilizing and the heart calming is powerful.Poria sweet in the mouth, light, property is flat, and sweet providing additional supplies oozed.The property gentle slow.Can promoting diuresis to eliminate damp pathogen, again can spleen-benefiting mind-tranquilizing.All retention of water-damp in the bodys and insufficiency of the spleenly all use always are also controlled irritability.Poria contains polysaccharose substance such as pachyman, pachymaran, triterpene substance such as pachymic acid, pachymic acid methyl ester; Also have materials such as fatty acid, ergosterol, natural gum, protein, hendecanoic acid, lauric acid, fat, choline; Still contain a spot of inorganic constituents and protease.Pachyman reaches 96.88% to the suppression ratio of murine sarcoma S180, has share obvious synergistic effect with cancer therapy drug.Pachyman has immunoregulation effect.Its decoct has inhibitory action to staphylococcus aureus, escherichia coli, Bacillus proteus, tubercule bacillus.Poria has significant protective effect to the rat hepatic injury, can increase the myocardial contraction of animal isolated heart.In addition, the Poria gastrointestinal smooth muscle that can relax, gastric acid inhibitory secretion.
Olibanum acrid in the mouth, hardship, warm in nature are gone into the heart, liver, spleen channel.There are regulating blood flow to alleviate pains, detoxifcation to treat the effect of skin ulcer.Arduous and the temperature of this product is fragrantly strongly walked to scurry, can repercussive blood, logical thinking, the meridian dredging, Shujin bone, damages of curing the wound, relieve the pain bitterly, and though the product for opening, right wasting QI-blood very not is for controlling the good medicine of blood and relieving pain.The diffusing evil detoxifcation of this product, the heart is protected in energy removing toxicity for eliminating carbuncles, Tuoli, and granulation promoting is put on flesh, and reducing swelling and alleviating pain is the key medicine of external wounds.With compatibilities such as Myrrha, Flos Lonicerae, Squama Maniss, can be used for controlling the carbuncle skin ulcer; With compatibilities such as Calculus Bovis, Moschus, Myrrhas, can be used for treating breast carcinoma, nodule in the breast etc.; With compatibilities such as Myrrha, Moschus, can be used for treating skin infection and do not hold back.The resinous 60-70% of Olibanum, gummy 27-35%, volatile oil 3-8%.Resin mainly contains α-boswellic acid, β-boswellic acid, α-Amyrin, β-Amyrin and derivant thereof.Main polysaccharide and the bassorin of containing of natural gum.Volatile oil mainly contains pinene, cinene, α-phellandrene etc.Olibanum has blood vessel dilating, the effect of microcirculation improvement.This product has significant analgesia role.Also have leukocyte increasing and anti-trichomonal effect.
Myrrha bitter in the mouth, suffering, property is flat, goes into the heart, liver, spleen channel.Have effect this product toil of diffusing blood blood stasis removing, reducing swelling and alleviating pain flat, can lead to can loose, can dissipating blood stasis blood, the stagnated blood that disappears, broken disease long-pending, qualcomm meridian, the heat in blood of loosing, treat carbuncle skin ulcer, granulation promoting meat, the pain that relieves the pain, be the key medicine of external wounds.Myrrha generally contains volatile oil 3-8%, poponax resin 25-45%, resin 55-60%, amaroid, myrrholic acid, formic acid, acetic acid, oxidase etc.Volatile oil contains compositions such as eugenol, cinnamic aldehyde.Resin contains α-commiphoric acid, β-commiphoric acid, γ-commiphoric acid etc.Resin hydrolyzing can get arabinose.Myrrha has significant analgesic activity.This product has convergence, antisepsis.This medicine has the heart of alleviation stricture of vagina pain and alleviates curative effect uncomfortable in chest.But the quantity of this product leukocyte increasing.Myrrha has the effect that suppresses bronchus, uterus excess secretion.Liquid medicine immersion (1: 2) has inhibitory action to multiple funguses such as trichophytons.Contained volatile oil has slight inhibitory action to mycete.This product still has diuresis.
The Flos Lonicerae sweet in the mouth, cold in nature.Return lung, the heart, stomach warp.Heat-clearing and toxic substances removing.This product heat-clearing and toxic substances removing power is quite strong.Be longer than that clearing heat in QI system heresy, saturating battalion reach gas, separate fire-toxin, subduing inflammation, be the skin infection key medicine.Its gas delicate fragrance, a surname looses gentle, heat clearing away and not feeling frustrated, removing toxic substances and non-impairment of YIN are for treating the good merchantable brand of warm fire-toxin.Eliminating pathogenic heat from blood to cure dysentery, this product is cold in nature and be so incensed that, kindly separates pyretic toxicity, disappear stop up stagnate, hot, the antidiarrheal dysentery of removing heat from blood.The pathogenic heat fire-toxin that Flos Lonicerae had both been cooled down branch and blood system can lead to battalion again and reach table, routed hard detumescence, separates the poison of carbuncle and ulcer.Be usually used in epidemic febrile disease, fever disease in summer, summer-heat, treatment poison, carbuncle sore, can be used for mange tinea corporis, breast carcinoma, dysentery etc.Flos Lonicerae contains chlorogenic acid, isochlorogenic acid; Also contain volatile oil, flavonoid, triterpenes, sweet-scented osmanthus flavin, sweet-scented osmanthus flavin-7-glycoside, caffeic acid, inositol, cupreol, Palmic acid, sucrose etc.; Still inorganic elementss such as iron content, manganese, copper, zinc.Flos Lonicerae has broad-spectrum antibacterial action, and multiple pathogenic microorganisms such as staphylococcus aureus, dysentery bacterium, leptospira, influenza virus and pathogenic moulds are had inhibitory action.Chlorogenic acid, isochlorogenic acid are antibiotic effective ingredient.This product has obvious anti-inflammatory and anti and Detoxication; Can promote leukocytes phagocytic, the stimulating central nervous system system; Immune system there is dual regulation; Protect the liver in addition, effect such as transaminase lowering, cholesterol reducing, antiearly pregnancy.
The present invention adopts following method manufacturing: take by weighing earlier Flos Lonicerae, Herba Hedyotidis Diffusae, Herba Lobeliae Chinensis, Herba Scutellariae Barbatae, Herba Crotalariae sessiliflorae, Radix Trichosanthis, Hirudo, Coriolous Dersicolor (Fr.) Quel, Pseudobulbus cremastrae seu pleiones, Squama Manis, Poria, Radix Aristolochiae, Bombyx Batryticatus in proportion, the water (weight ratio) that adds 5 times soaked after 2 hours, cure in the interlayer digester and heat, after very hot oven boils, use slow fire boiling instead 2 hours, and adopted pressure filter to leach medicinal liquid.It is concentrated to place vacuum concentrator to heat medicinal liquid, treats that medicinal liquid is concentrated into 1/3 o'clock of original liquid and takes out stand-by.Olibanum, Myrrha, Radix Notoginseng are pulverized the back with pulverizer cross 120 order dusting covers, be blended into Calculus Bovis, Moschus again, with concentrated medicament and medicated powder convert stir with blender together after, make pill with pellet processing machine by the specification of 80/10g, by the specification packing of every bottle 10 gram; Or make sheet by the specification of every 0.25g/ sheet with tablet machine, pack with the tinfoil paper plastic compression by the specification of 12/plate with the plastic compression machine.
The various medicines of prescription of the present invention are compatible directly to suppress or kill cancerous cell, strengthen the function of reticuloendothelial cell, stronger active anticancer is arranged and contain many cells oleo stock material, with cellular enzymes albumen sulfydryl very strong affinity is arranged, but the oxidizing process of anticancer disturbs its homergy to make it to take place coagulation necrosis.Again can stimulating central nervous system, cell activity enhancing, appetite stimulator, thus improve the autoimmune ability.Reasonable recipe of the present invention, curative effect is obvious, can reach 100% to carcinoid effective percentage, treatment effective percentage to malignant tumor can reach more than 90%, curative effect to the early metaphase malignant tumor is better, the patient is eased the pain and prolongs the existence life-span late malignant tumour, improves life quality.It is little that medicine of the present invention has toxic and side effects, and patient economy burden is light, the characteristics of taking convenience.
The specific embodiment
In order to understand better and to implement, the present invention is described in detail below in conjunction with embodiment.
Example 1 takes by weighing Herba Crotalariae sessiliflorae 30kg.Herba Hedyotidis Diffusae 50kg, Herba Scutellariae Barbatae 30kg, Herba Lobeliae Chinensis 20kg, Radix Trichosanthis 10kg, Hirudo 6kg, Squama Manis 10kg, Pseudobulbus cremastrae seu pleiones 10kg, Coriolous Dersicolor (Fr.) Quel 10kg, Radix Aristolochiae 10kg, Bombyx Batryticatus 6kg, Poria 10kg, Flos Lonicerae 30kg, the water (by weight) that adds 5 times soaked after 2 hours, placed the interlayer digester to heat, after very hot oven boils, use slow fire boiling instead after 2 hours, adopt pressure filter to leach medicinal liquid.It is concentrated to place vacuum concentrator to heat medicinal liquid, treats that medicinal liquid is concentrated into 1/3 o'clock of original liquid and takes out stand-by.Take by weighing Olibanum 6kg; Myrrha 10kg; Radix Notoginseng 6kg; pulverize the back with pulverizer and cross 120 order dusting covers; be blended into Calculus Bovis 1kg again, Moschus 1kg, with concentrated medicament and medicated powder convert stir with blender together after; make pill with pellet processing machine by the specification of 80/10g, pack by the specification of every bottle 10 gram.
Example 2 takes by weighing Herba Crotalariae sessiliflorae 35kg, Herba Hedyotidis Diffusae 60kg, Herba Scutellariae Barbatae 35kg, Herba Lobeliae Chinensis 25kg, Radix Trichosanthis 12kg, Hirudo 8kg, Squama Manis 12kg, Pseudobulbus cremastrae seu pleiones 11kg, Coriolous Dersicolor (Fr.) Quel 12kg, Radix Aristolochiae 12kg, Bombyx Batryticatus 8kg, Poria 12kg, Flos Lonicerae 35kg adds 5 times water (by weight), soaks after 2 hours, place the interlayer digester to heat, after very hot oven boils, use slow fire boiling instead after 2 hours.Adopt pressure filter to leach medicinal liquid.It is concentrated to place vacuum concentrator to heat medicinal liquid, treats that medicinal liquid is concentrated into 1/3 o'clock of original liquid and takes out stand-by.Take by weighing Olibanum 7kg; Myrrha 11kg; Radix Notoginseng 7kg; pulverize the back with pulverizer and cross 120 order dusting covers; be blended into Calculus Bovis 1.5kg again, Moschus 1.5kg, with concentrated medicament and medicated powder convert stir with blender together after; make pill with pellet processing machine by the specification of 80/10g, pack by the specification of every bottle 10 gram.
Example 3 takes by weighing Herba Crotalariae sessiliflorae 40kg, Herba Hedyotidis Diffusae 70kg, Herba Scutellariae Barbatae 40kg, Herba Lobeliae Chinensis 30kg, Radix Trichosanthis 14kg, Hirudo 10kg, Squama Manis 14kg, Pseudobulbus cremastrae seu pleiones 12kg, Coriolous Dersicolor (Fr.) Quel 14kg, Radix Aristolochiae 14kg, Bombyx Batryticatus 10kg, Poria 14kg, Flos Lonicerae 40kg, the water (by weight) that adds 5 times soaked after 2 hours, placed the interlayer digester to heat, after very hot oven boils, use slow fire boiling instead after 2 hours, adopt pressure filter to leach medicinal liquid.It is concentrated to place vacuum concentrator to heat medicinal liquid, treats that medicinal liquid is concentrated into 1/3 o'clock of original liquid and takes out stand-by.Take by weighing Olibanum 8kg; Myrrha 12kg; Radix Notoginseng 8kg; pulverize the back with pulverizer and cross 120 order dusting covers; be blended into Calculus Bovis 2kg again, Moschus 2kg, with concentrated medicament and medicated powder convert stir with blender together after; make pill with pellet processing machine by the specification of 80/10g, pack by the specification of every bottle 10 gram.
Example 4 takes by weighing Herba Crotalariae sessiliflorae 45kg, Herba Hedyotidis Diffusae 80kg, Herba Scutellariae Barbatae 45kg, Herba Lobeliae Chinensis 35kg, Radix Trichosanthis 15kg, Hirudo 12kg, Squama Manis 16kg, Pseudobulbus cremastrae seu pleiones 13kg, Coriolous Dersicolor (Fr.) Quel 16kg, Radix Aristolochiae 16kg, Bombyx Batryticatus 12kg, Poria 16kg, Flos Lonicerae 45kg.The water (by weight) that adds 5 times soaked after 2 hours, placed the interlayer digester to heat, and after very hot oven boils, used slow fire boiling instead after 2 hours, adopted pressure filter to leach medicinal liquid.It is concentrated to place vacuum concentrator to heat medicinal liquid, treats that medicinal liquid is concentrated into 1/3 o'clock of original liquid and takes out stand-by.Take by weighing Olibanum 9kg; Myrrha 13kg; Radix Notoginseng 9kg; pulverize the back with pulverizer and cross 120 order dusting covers; be blended into Calculus Bovis 2.5kg again, Moschus 2.5kg, with concentrated medicament and medicated powder convert stir with blender together after; make pill with pellet processing machine by the specification of 80/10g, pack by the specification of every bottle 10 gram.
Example 5 takes by weighing Herba Crotalariae sessiliflorae 50kg, Herba Hedyotidis Diffusae 90kg, Herba Scutellariae Barbatae 50kg.Herba Lobeliae Chinensis 40kg, Radix Trichosanthis 16kg, Hirudo 14kg, Squama Manis 18kg, Pseudobulbus cremastrae seu pleiones 14kg, Coriolous Dersicolor (Fr.) Quel 18kg, Radix Aristolochiae 18kg, Bombyx Batryticatus 7kg, Poria 11kg, Flos Lonicerae 50kg adds 5 times water (by weight), soaks after 2 hours, place the interlayer digester to heat, after very hot oven boils, use slow fire boiling instead after 2 hours, adopt pressure filter to leach medicinal liquid.It is concentrated to place vacuum concentrator to heat medicinal liquid, treats that medicinal liquid is concentrated into 1/3 o'clock of original liquid and takes out stand-by.Take by weighing Olibanum 10kg; Myrrha 14kg; Radix Notoginseng 10kg; pulverize the back with pulverizer and cross 120 order dusting covers; be blended into Calculus Bovis 3kg again, Moschus 3kg, with concentrated medicament and medicated powder convert stir with blender together after; make sheet with tablet machine by the specification of every 0.25g/ sheet, pack with the tinfoil paper plastic compression by the specification of 12/plate with the plastic compression machine.
Example 6 takes by weighing Herba Crotalariae sessiliflorae 37kg, Herba Hedyotidis Diffusae 100kg, Herba Scutellariae Barbatae 37kg, Herba Lobeliae Chinensis 45kg, Radix Trichosanthis 18kg, Hirudo 15kg, Squama Manis 20kg, Pseudobulbus cremastrae seu pleiones 15kg, Coriolous Dersicolor (Fr.) Quel 20kg, Radix Aristolochiae 20kg, Bombyx Batryticatus 9kg, Poria 13kg, Flos Lonicerae 33kg, the water (by weight) that adds 5 times soaked after 2 hours, placed the interlayer digester to heat, after very hot oven boils, use slow fire boiling instead after 2 hours, adopt pressure filter to leach medicinal liquid.It is concentrated to place vacuum concentrator to heat medicinal liquid, treats that medicinal liquid is concentrated into 1/3 o'clock of original liquid and takes out stand-by.Take by weighing Olibanum 11kg; Myrrha 15kg; Radix Notoginseng 11kg; pulverize the back with pulverizer and cross 120 order dusting covers; be blended into Calculus Bovis 1.25kg again, Moschus 1.25kg, with concentrated medicament and medicated powder convert stir with blender together after; make sheet with tablet machine by the specification of every 0.25g/ sheet, pack with the tinfoil paper plastic compression by the specification of 12/plate with the plastic compression machine.
Example 7 takes by weighing Herba Crotalariae sessiliflorae 47kg, Herba Hedyotidis Diffusae 75kg, Herba Scutellariae Barbatae 47kg, Herba Lobeliae Chinensis 50kg, Radix Trichosanthis 20kg, Hirudo 13kg, Squama Manis 15kg, Pseudobulbus cremastrae seu pleiones 12.5kg, Coriolous Dersicolor (Fr.) Quel 15kg, Radix Aristolochiae 15kg, Bombyx Batryticatus 11kg, Poria 15kg, Flos Lonicerae 37kg, the water (by weight) that adds 5 times soaked after 2 hours, placed the interlayer digester to heat, after very hot oven boils, use slow fire boiling instead after 2 hours, adopt pressure filter to leach medicinal liquid.It is concentrated to place vacuum concentrator to heat medicinal liquid; treat that medicinal liquid is concentrated into 1/3 o'clock of original liquid and takes out stand-by; take by weighing Olibanum 12kg, Myrrha 12.5kg, Radix Notoginseng 12kg; pulverize the back with pulverizer and cross 120 order dusting covers; be blended into Calculus Bovis 1.75kg again, Moschus 1.75kg, with concentrated medicament and medicated powder convert stir with blender together after; make sheet with tablet machine by the specification of every 0.25g/ sheet, pack with the tinfoil paper plastic compression by the specification of 12/plate with the plastic compression machine.
1, clinical diagnosis and criterion of cure
1.1 list of references: the Chinese medicine industry standard ZY/T001.1-001.9-94 of the People's Republic of China (PRC) " traditional Chinese medical science disease diagnosis criterion of therapeutical effect " (publishing house of issue Nanjing University of State Administration of Traditional Chinese Medicine 1994 July the 1st edition).
" practical traditional Chinese medical science oncosis learn " Li Jiageng Qu Songbai chief editor (scientific and technical literature publishing house February calendar year 2001 the 2nd edition)
" the clinical handbook Liu Shen Lin of modern Chinese medicine Zhu Yongkang chief editor (Jiangsu science tech publishing house June calendar year 2001 the 1st edition)
" surgery " Wu Zaide chief editor (People's Health Publisher February calendar year 2001 the 5th edition)
" practical surgery handbook Li Biao Wu Jin art is write (Hunan science tech publishing house 2000 November the 1st edition)
1.2 clinical diagnosis and efficacy evaluation
1.2.1 thyroid tumor
Thyroid tumor is many because of feelings will internal injury, and expectorant is turbid to be condensed, and is poly-and in bulk is sent out in the Adam's apple both sides, with swallowing and move up and down.It is thin that the traditional Chinese medical science is referred to as meat.
Diagnosis basis
Lump in the wart capsule, rounded, smooth surface moves up and down with swallowing, no pain and tenderness.Concurrent when hemorrhage, lump can increase rapidly, with distending pain.When lump increases, dyspnea can be arranged, dysphagia, compressing such as hoarseness symptom.Primary disease is more common in blue or green middle-aged women.Ultrasound investigation and radioisotope scan help diagnosis.The inspection of the former amino acid of serum triiodo thyroid (T3), the former amino acid of serum tetraiodo thyroid (T4) and thyrotropin (TSH) can be understood thyroid function.
Syndrome-classification:
Stagnation of QI expectorant coagulates: neck region lump, and not red, not hot, not bitterly, move up and down with swallowing, hypopnea or dysphagia can be arranged.General no obvious General Symptoms.Greasy and thin fur, stringy and rolling pulse.
Deficiency of both QI and YIN: local symptom is the same.Irascible temperament, irritability is afraid of antiperspirant, easy antiperspirant, bitter taste, cardiopalmus, insomnia, dreaminess, receipts are quivered, and kind food is become thin menoxenia.Red tongue, thin fur, stringy pulse.
Efficacy evaluation:
Cure: local lump and General Symptoms disappear.
Take a turn for the better: local lump dwindles, and General Symptoms alleviates.
Do not heal: local lump does not have and dwindles, and General Symptoms does not have improvement.
1.2.2 breast carcinoma
Breast carcinoma is by feelings will internal injury, Chong and Ren channel disorder, and stagnation of QI phlegm and blood stasis forms.Breast portion caking, quality is hard, is uneven, and sick lump for a long time festers, the filthy stench of pus and blood, pain increases day by day, but the later stage focus shifts.The traditional Chinese medical science is referred to as breast carcinoma.
Diagnosis basis
Great majority occur in the 45-60 women in year, especially with unmarried or after marriage the nullipara see more.Initial stage: a lump is arranged in the breast, be more common in outer top, quality is hard.The surface is uneven, and grows up gradually.Mid-term: for years, the beginning feel has pain in various degree.Lump shape is as heap chestnut or cover bowl, with the surrounding tissue adhesion, and skin nuclear phase parent, what push away is motionless, and skin is " Pericarpium Citri Reticulatae sample " and changes, retracted nipple or raise.If color of the leather is purple brown, the last cloth blood streak is about to fester.Later stage: the back rock of bursting is swollen harder, and open sore part edge is uneven.The intermediate recess that has is very dark, shape such as cave; The height that has is prominent, shape such as magic flower, the smelly dirty blood and slime of permanent current.The swelling of Ipsilateral upper limb.Can be in the Ipsilateral oxter, supraclavicular fossa up and down recess contact scleroid lump, or transfer to internal organs or skeleton.Heating can appear, Mental fatigue, dysphoria and insomnia, diseases such as emaciated physique.Molybdenum palladium X line breast is taken the photograph the courageous and upright secretions cytolgical examination of sheet, the inspection of liquid crystal thermography picture, nipple and is helped diagnosis.To do tissue pathology checking in case of necessity.
Syndrome-classification
Liver energy depression and phlegm stagnation: property will depression, or irascible temperament, rib uncomfortable in chest expands, or the companion does bloated or lack abdomen to expand through fore udder.Breast portion lump color of the leather is constant.Tongue is white, stringy pulse.
Chong and Ren channel disorder: through the thing disorder, through the fore udder distending pain.Or fertility never after marriage, or the history of repeatedly miscarrying.Pale tongue, thin fur, stringy and thready pulse.
Weakened body resistance poison is vehement: lump enlarges, and the back of bursting is harder, seepage flow blood and slime, not bitterly or severe pain.Lethargy, dim complexion or pale, diet advances less, palpitation and insomnia.Purplish tongue or ecchymosis is arranged, tongue English, weak pulse is unable.
Efficacy evaluation
Cure: lump dissipates.Take a turn for the better: lump dwindles or keeps stable.Do not heal: lump increases, and General Symptoms does not have improvement or sees deterioration.
1.2.3 cyclomastopathy
Cyclomastopathy is by feelings will internal injury, Chong and Ren channel disorder.The expectorant stasis of blood is condensed and is formed.Lump in breast is relevant with menstrual cycle with pain.Be equivalent to cyclomastopathy.
Diagnosis basis
Most breast outside on quadrant one flat lump is arranged, that lays one's hand on has a big or small tough hard tubercle of beans, and tenderness can be arranged.Owe clearly on the lump border, with the surrounding tissue adhesion.Breast can have distending pain, and the growth and decline with susceptible to anger whenever increase the weight of before the menstruation of being everlasting, and alleviate after the menstruation.20-40 that primary disease sees year women.Molybdenum palladium X line breast is taken the photograph inspections such as sheet, cold light source strong illumination, liquid crystal thermography picture and is helped diagnosis.Make histopathological examination in case of necessity.
Syndrome-classification
Liver stasis of blood expectorant coagulates: be more common between twenty and fifty women.Lump in breast expands with rib uncomfortable in chest with the susceptible to anger growth and decline, kind strongly fragrant irritability, insomnia and dreamful sleep, vexed bitter taste.The thin lingual fur sprout.Stringy and rolling pulse.
Chong and Ren channel disorder: be more common in middle-aged women.Increase the weight of before the lump in breast menstruation, through after extenuate.Weak with the soreness of waist, tired, menstruation is successively lacked of proper care, and the few color of amount is light, or amenorrhea.Light red tongue, tongue is white, deep-thready pulse.
Efficacy evaluation
Cure; Lump in breast and pain disappear.Take a turn for the better: lump in breast dwindles, pain relief or disappearance.Do not heal: lump in breast and pain no change.
1.2.4 pulmonary carcinoma
The clinical zest that can occur in early days is in coughing, white mucus spume expectorant, or sputum mixed with blood silk, or hemoptysis, or chest pain is arranged, chest discomfort, dyspnea and heating etc.; Middle and advanced stage corresponding sings and symptoms can occur because the tumor body blocks bronchus and oncothlipsis, transfer.
Diagnostic point
1. paroxysmal irritable cough, most advanced and sophisticated sputum mixed with blood or lasting hemoptysis, the intractable chest pain should be suspected pulmonary carcinoma when the low grade fever of unknown cause or hoarseness.2. repeatedly with the pneumonia of a part, the pulmonary atelectasis of unknown cause, the regular anti-consumptive disease of " pulmonary tuberculosis " patient are failed to respond to any medical treatment or shade increases.3. patients with terminal can have the supraclavicular lymph nodes enlargement, hydrothorax, and superior vena cava is comprehensively demonstrate,proved, and diaphragmatic paralysis or other internal organs shift.4. the X ray examination can have one-sided hilus pulumonis lump, obstructive pneumonia, pulmonary atelectasis, isolatism piece shadow (often being lobulated), limitation emphysema or two lung diffusivity tuberosity shades etc.5. sputum and bronchoscope aspirate can find cancerous cell in direct smear or the hydrothorax under the bronchoscope.6. the lung puncture and the metastatic lymph node biopsy pathology positive.
Syndrome-classification
Insufficiency of the spleen phlegm-damp: cough ant phlegm, uncomfortable in chest indigestion and loss of appetite, sallow complexion.Big loose stool is thin.Pale tongue is fat, and tongue is greasy in vain, relaxed and soft pulse or moisten cunning.
Interior-heat caused by deficiency of YIN: cough but no phlegm or few expectorant, or sputum mixed with blood, uncomfortable in chest, breathe hard vexed insomnia, dry mouth and constipation or low night sweat brimful of tears.Red tongue, tongue stripping or light stripping no fur, thready and rapid pulse.
Deficiency of both QI and YIN: few expectorant of cough or sputum mixed with blood, breathe hard, weak.The thin aversion to wind of shape, spontaneous perspiration or night sweat, or low grade fever, xerostomia is not desired polydipsia.Red tongue or light red, tongue is white, thready and weak pulse.
Qi depression to blood stasis: it is uncomfortable in chest to cough, and it is not well to cough up phlegm, fullness and distention in the chest and hypochondrium or twinge, the time sputum mixed with blood, constipation with dry stool arranged.Purplish tongue or the ecchymosis petechia is arranged, stringy pulse or carefully puckery.
Cure: lump and pain disappear.Take a turn for the better: lump dwindles, pain relief or disappearance.Do not heal: lump and pain no change.
1.2.5 gastric cancer
Secondly the gastric antrum portions that see more than half are at the bottom of cardia, the stomach or position such as body of stomach.Early cancer's tissue is limited to mucous layer and tela submucosa, and the middle and advanced stage cancerous tissue soaks into and reaches flesh layer or serous coat.Clinical early stage gastral cavilty portion dull pain, the food back is vexed full, becomes thin the appetite decay; Do not heal for a long time if see have a pain aggravation and pain of vomiting or gastral cavilty portion, when touching lump, or hematemesis or have blood in stool, belong to late period more.
Diagnostic point
1. gastric cancer has mainly showed epigastrium dull pain, inappetence, and stomach is swollen, and it is weak to become thin, hematemesis or have blood in stool, or acataposis is arranged, block phenomenon.Gastritis, gastric ulcer history are often arranged, and to become thin appear in the later stage, anemia, weakness, heating, edema.2. x-ray barium meal examination: this inspection to typically than patient diagnosis rate height in late period, but not high to the diagnosis of early gastric cancer.Adopt dual gas barium contrast radiography can improve positive rate.3. fibergastroscopy: the biopsy that exfoliative cyte that fibergastroscopy tuberculosis brush is got or pincers are got the fritter specimen is the reliable means of diagnosis of gastric cancer.This method diagnosis is more accurate, and diagnosis rate can reach more than 95%.4. stool occult blood test is the persistence positive more, and gastric analysis can show low acid or acid deficient.
Syndrome-classification.Stagnation of QI causing phlegm retention: gastral cavilty distending pain or connect and both sides of the chest, the cold acid of belch, very then singultus is felt sick, and inappetence is detested carnivorously, and the white or little Huang of tongue fur is greasy.Wiry and frequent pulse.
Deficiency and coldness of spleen and stomach: spiritlessness and weakness, light red tongue lack magnificent lack of appetite gastral cavilty has a pain, and likes warm pain relieved by pressing, and vomiting clear water or sticking expectorant also have vomiting place trencherman, and the cold physique happiness is warm, and light red tongue is and fat, and thin fur moistens, deep-slow pulse.
Stasis of blood poison internal resistance: gastral cavilty twinge, scorching hot causalgia, postprandial pain play, localized pain, the gastral cavity tenderness that expands.Epigastric oppression piece, or have hematemesis to have blood in stool, skin glues dry first mistake, purplish tongue or see petechia, deep and stringy pulse, carefully wet or stringy and rapid pulse.
Deficiency of both QI and YIN: gastral cavity portion lump day by day increases, and the pain increased, lusterless complexion, and refreshing flaccidity is weak, and emaciated physique is moving then breathe hard.Spontaneous sweating.The few tongue of light red tongue.Deep-thready pulse.
Cure: lump and pain disappear.Take a turn for the better: lump dwindles, pain relief or disappearance.Do not heal: lump and pain no change.
2, clinical data.Accepted 158 routine patients altogether for medical treatment from 1998 in April, 2002, the curative effect situation is as shown in the table:
Name of disease The example number Cure Take a turn for the better Cure rate (%) Effective percentage (%)
Thyroid tumor 52 52 100 100
Cyclomastopathy 46 46 100 100
Breast carcinoma 31 27 4 87 100
Gastric cancer 17 9 5 53 82
Pulmonary carcinoma 12 7 2 58 75
Add up to 158 141 11 89 96
3, administrated method.Day three times, 6 or 3 successively, one after each meal, 30 is a course of treatment.The taboo of taking medicine: stimulus object avoids pungent food.Group food as Herba Alii fistulosi, Fructus Capsici, Pupa bombycis, Eriocheir sinensis, fish, shrimp, Tonnae Sinensis; Avoid direct stimulation.
4, the various medicines of prescription of the present invention are compatible can directly suppress or kill cancerous cell, strengthen the function of reticuloendothelial cell, stronger active anticancer is arranged and contain cell oleo stock material to some extent, dredge base with cellular enzymes albumen very strong affinity is arranged, but the oxidizing process of anticancer disturbs its homergy to make it to take place the blood coagulation necrosis.Again can stimulating central nervous system, cell activity enhancing, appetite stimulator, thus improve the autoimmune ability; The various medicines of prescription of the present invention are compatible simultaneously can increase the sensitivity that chemicals kills and wounds cancerous cell, also can lower the toxic and side effects of chemicals, also have anticancer cell multiple medicines, drug resistance and cancer cell specific induction of apoptosis effect, can cooperate radiotherapy, chemotherapy to carry out simultaneously, play better therapeutical effect.
As can be seen, the mutual compatibility of various medicines that prescription of the present invention adopted is consistent with the principles of formulating prescriptions of blood circulation promoting and blood stasis dispelling, anti-inflammatory analgetic, heat-clearing and toxic substances removing, enhance immunity ability from above discussion.
5, model case
Example 1, king * *, woman, 71 years old, bar people from village under Xixia City, the Shandong Province booth mouth town.The People's Hospital, 16 Nikkei Xixia City in April calendar year 2001 fibergastroscopy is diagnosed as gastric cancer, piebaldism, and ulcer, III type, cancerous protuberance are 8 * 3cm/cm, come May 5 calendar year 2001 here to go to a doctor.Appetite strengthens after coming further consultation, private prosecution to take medicine on May 18, loses the sense of taste and is recovered, and can be engaged in housework, does not have any pain.The fibergastroscope check of the People's Hospital, 9 Nikkei Xixia City in June, lump is reduced into 4cm/cm, the II type.Following up a case by regular visits to so far, lump does not increase.
Example 2, Cui * *, man, 48 years old, Guia Hill, Xixia City town Mt. Ai soup village peasant.Be diagnosed as pulmonary carcinoma and lymphatic metastasis has taken place through the People's Hospital, Xixia City, Affiliated Hospital of Qingdao Medical Inst, can't perform the operation, hydrothorax can extract about 3000ml at every turn.July 5 calendar year 2001, the Nikkei people introduced here to go to a doctor.Further consultation on July 19, the thoracic cavity does not have hydrops, and appetite increases, and spirit takes a turn for the better.The check of the People's Hospital, JIUYUE 13 Nikkei Xixia City, lymphatic metastasis disappears, and weight in patients increases by 6.5 kilograms.Follow up a case by regular visits to so far still orthobiosis.
Example 3, woods * *, woman, 40 years old, Shandong Province Dezhou City people.Be diagnosed as bilateral breast hypertrophy, moderate through the Dezhou City the People's Hospital in 1998.Through treatment for many years, disease cuts in and out, the time heavy when light.Spring calendar year 2001 bilateral breast hypertrophy increases the weight of, and lump is big as egg, the enlargement of companion's bilateral axillary lymph knot, and heating pain is radiated to omoplate portion, and evening is insomnia bitterly, anorexia.Come July 15 calendar year 2001 here to go to a doctor.The 3rd day pain relief of taking medicine, lump dwindles to some extent.Further consultation on July 25, lump disappears substantially, and pain is removed, and further consultation on August 6 has recovered normal.Follow up a case by regular visits to not recurrence so far,
Example 4, Lee *, the woman, 24 years old, people from Weihai City, Shandong Province, suitable menstrual period in the time of before 3 years, because of work wrong criticized by the leader after, the beginning left breast is swollen, and slight pain is arranged.After menstrual period, distending pain increased the weight of whenever, clothes the antibiotic medicine after sx.Cause failure in love in 2 years causes the state of an illness to increase the weight of, the bilateral breast swell and pain.Colored ultrasound diagnosis is diagnosed as bimastism severe cyclomastopathy through the People's Hospital, Weihai City, lump 3 * 5 cm/, and two axillary lymph knot enlargements of companion simultaneously such as egg have a dull ache sometimes, and sometimes as acupuncture, the state of an illness increased the weight of after anger was got angry.Seek medical advice through many places and to come here to see a doctor April 22 calendar year 2001 after invalid.Further consultation on April 29, the state of an illness is greatly improved, and lump has dwindled 1/2, pain relief, spiritual amelioration.Further consultation on May 6, lump disappears, and the enlargement of axillary lymph knot also disappears.Go back to Weihai after the former hospital of making a definite diagnosis checks, recurrence is followed up a case by regular visits to so far in the cyclomastopathy recovery from illness.
Example 5, Liu * *, woman, 48 years old, Xixia City, Shandong Province booth mouth town Huang Jiagou people from village.Be diagnosed as thyroid tumor through the People's Hospital, Xixia City March calendar year 2001,4 * 5 cm/.After failing to respond to any medical treatment in many places, come here to go to a doctor June 14 calendar year 2001.The People's Hospital, 27 Nikkei Xixia City in June checks that tumor is reduced into 2 * 2.5 cm/.Checked through the People's Hospital, Xixia City again that tumor disappears on July 16.Follow up a case by regular visits to not recurrence so far.
Example 6, open * *, man, 62 years old, Xinjiang retired cadre (Xixia City, ancestral home).Come here first visit, private prosecution August 1 calendar year 2001: the expectorant blood of coughing the year before.June calendar year 2001, the 24 Nikkei Shandong Province North Sea, Longkou City hospital was diagnosed as cavernous lung cancer, and empty wall is uneven.Clapping rabat August 29 shows: focus is clearly better.The film making check of the People's Hospital, 21 Nikkei Xixia City in November calendar year 2001, former big lamellar shade disappears conclusion: former pulmonary carcinoma disappears.
Example 7, king * *, woman, 41 years old.Xixia City Zang Jiazhuan town Xiao Luan family people from village.On March 1st, 2002 went to a doctor.The main suit: suffer from influenza the year before winter, more aftersensation is weak all over, and the time has uncomfortable in chest nervously, and neck has the sense of swelling.Local township doctor is diagnosed as hyperthyroidism, fails to respond to any medical treatment one year over, and the state of an illness increases the weight of on the contrary.After the ultrasound diagnosis of the People's Hospital, Xixia City is diagnosed as thyroid tumor.Lobus sinister: 5.6 * 2.6 * 2.5 centimetres, lobus dexter: 5.8 * 2.3 * 2.4 centimetres, further consultation on March 16, the lobus sinister lump disappears substantially on inspection, and the lobus dexter lump dwindles half.Matter is soft.Further consultation once more on April 2, the bilateral thyroid tumor disappears on inspection, and all cards also disappear, and the patient can normally participate in rural labor.
Example 8, Rhizoma Zingiberis Recens * *, woman, 52 years old, Laiyang City Feng Gezhuan town, Shandong Province Feng Ge village people from village.On March 16th, 1998 went to a doctor, the main suit: in December, 1997 is got married for son makes arrangements of, and about afterwards first quarter moon left and right sides chronognosis right breast is generated heat, bloated sense.Some alleviates behind the clothes Western medicine antibiotic medicine, has crossed a period of time rear udder attachment distending pain, and several little lumps are arranged, big person such as Fructus Jujubae shape, go to the Laiyang City the People's Hospital to check and be breast carcinoma, introduce through friend, go to a doctor on March 16th, 1998: examine on April 2 two: the mammary swelling pain is clearly better, originally less lump touch less than, as the Fructus Jujubae shape to dwindle into Semen arachidis hypogaeae big, this medicine of clothes that continues, examine on April 13 three: breast does not have any lump, breast is saturating, and all are normal, follow up a case by regular visits to after 1 year and do not have recurrence.
Example 9, Xing * *, woman, 62 years old, people from village of Xixia City, Shandong Province booth mouth town Xing family.On March 24th, 2000 went to a doctor, the main suit: did heart Bicuspid valve dilatation before 17 years, pericardium has hydrops now, a cat fever before 6 months, and left breast begins that uncomfortable sensation is arranged, and lump in breast increases gradually.Check through the People's Hospital, Xixia City, be diagnosed as breast carcinoma, 8 * 12 centimetres of lumps.The household do not believe, after go to Yantai City tumour hospital to check again, make a definite diagnosis undoubtedly.Because of having heart disease and household economy can't undergo surgery than difficulty.Left side crater nipple, shrunken skin such as orange peel shape during prescription on individual diagnosis.Purple dark-coloured, lump blur margin, axillary lymph knot enlargement such as egg.Pain is two wheat harvesting periods unbearably, can not lie in bed round the clock, can only sleep by sitting posture, keep by the strong analgesics.Take medicine of the present invention pain relief after 4 days, can lie up.Examine on March 30 two: after private prosecution is taken medicine always not the pain mistake.Examine on May 5 three, and on inspection, lump in breast dwindles 1/2, and skin color becomes normally, the open and flat nature of skin, and concavo-convex shrinkage phenomenon is eliminated, and the saturating lump of checking of breast disappears, and spirit is as ordinary person.Follow up a case by regular visits to after half a year and do not have recurrence.
Example 10, king * *, the woman, 63 years old, Mouping District Zhenyang, Yantai City people from residential district came here to go to a doctor April 2 calendar year 2001.Second the People's Hospital is diagnosed as gastric cancer through gastroscope, color ultrasound examination to the patient in the Mouping before January, paries posterior gastricus 6 * 8 centimetres of lumps of having an appointment, and food is tasteless.Abdominal distention, lumbar and back pain,, there is vomiting in time, feels sick, and through the poor effect of seeking medical advice in many ways, relies on the opium pain relieving.Take course of treatment behind the said preparation, pain relief, abdominal distention is eliminated, and can be engaged in certain recreation.June 28, Nikkei Yantai City tumour hospital checked, lump narrows down to 4 * 5 centimetres.JIUYUE 10 Nikkei Yantai 107 examination in hospital, lump disappears, and can only see connective tissue is focus.The patient lives, and all are normal.Can be engaged in normal housework.Follow up a case by regular visits to not recurrence so far.

Claims (1)

1, a kind of medicine for the treatment of oncosis, in weight portion, it is by Herba Crotalariae sessiliflorae 30-50 part, Herba Hedyotidis Diffusae 50-100 part; Herba Scutellariae Barbatae 30-50 part, Herba Lobeliae Chinensis 20-50 part, Radix Trichosanthis 10-20 part, Hirudo 6-15 part; Moschus 1-3 part, Calculus Bovis 1-3 part, Squama Manis 10-20 part, Radix Notoginseng 6-12 part; Pseudobulbus cremastrae seu pleiones 10-15 part, Coriolous Dersicolor (Fr.) Quel 10-20 part, Radix Aristolochiae 10-20 part; Bombyx Batryticatus 6-12 part, Poria 10-16 part, Olibanum 6-12 part; Myrrha 10-15 part, Flos Lonicerae 30-50 part is by being processed into pill or tablet forms.
CNB021103895A 2002-05-13 2002-05-13 Tumor treating medicine Expired - Fee Related CN1180815C (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102671070A (en) * 2012-06-01 2012-09-19 雷喻天 Traditional Chinese medicine composition for treating cancers or tumors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102671070A (en) * 2012-06-01 2012-09-19 雷喻天 Traditional Chinese medicine composition for treating cancers or tumors

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