CN117979945A - Composition for conditioning or caring for keratin materials - Google Patents
Composition for conditioning or caring for keratin materials Download PDFInfo
- Publication number
- CN117979945A CN117979945A CN202180102673.6A CN202180102673A CN117979945A CN 117979945 A CN117979945 A CN 117979945A CN 202180102673 A CN202180102673 A CN 202180102673A CN 117979945 A CN117979945 A CN 117979945A
- Authority
- CN
- China
- Prior art keywords
- composition
- oil
- surfactant
- combinations
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 80
- 239000000463 material Substances 0.000 title claims abstract description 28
- 102000011782 Keratins Human genes 0.000 title claims abstract description 24
- 108010076876 Keratins Proteins 0.000 title claims abstract description 24
- 230000003750 conditioning effect Effects 0.000 title claims abstract description 22
- 239000002736 nonionic surfactant Substances 0.000 claims abstract description 29
- 239000003960 organic solvent Substances 0.000 claims abstract description 27
- 239000004094 surface-active agent Substances 0.000 claims abstract description 23
- 239000002537 cosmetic Substances 0.000 claims abstract description 20
- 239000002563 ionic surfactant Substances 0.000 claims abstract description 16
- 238000000034 method Methods 0.000 claims abstract description 7
- 230000008569 process Effects 0.000 claims abstract description 5
- 239000003921 oil Substances 0.000 claims description 99
- -1 ether hydrocarbon Chemical class 0.000 claims description 79
- 229920000223 polyglycerol Polymers 0.000 claims description 27
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 24
- 125000000217 alkyl group Chemical group 0.000 claims description 18
- 125000004432 carbon atom Chemical group C* 0.000 claims description 18
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 18
- 239000004480 active ingredient Substances 0.000 claims description 17
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 16
- NKJOXAZJBOMXID-UHFFFAOYSA-N 1,1'-Oxybisoctane Chemical compound CCCCCCCCOCCCCCCCC NKJOXAZJBOMXID-UHFFFAOYSA-N 0.000 claims description 15
- 239000003093 cationic surfactant Substances 0.000 claims description 15
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 15
- 239000003945 anionic surfactant Substances 0.000 claims description 13
- SGVYKUFIHHTIFL-UHFFFAOYSA-N Isobutylhexyl Natural products CCCCCCCC(C)C SGVYKUFIHHTIFL-UHFFFAOYSA-N 0.000 claims description 12
- 229930195733 hydrocarbon Natural products 0.000 claims description 11
- GTJOHISYCKPIMT-UHFFFAOYSA-N 2-methylundecane Chemical compound CCCCCCCCCC(C)C GTJOHISYCKPIMT-UHFFFAOYSA-N 0.000 claims description 10
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 10
- VKPSKYDESGTTFR-UHFFFAOYSA-N isododecane Natural products CC(C)(C)CC(C)CC(C)(C)C VKPSKYDESGTTFR-UHFFFAOYSA-N 0.000 claims description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 9
- 239000004215 Carbon black (E152) Substances 0.000 claims description 8
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims description 8
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims description 8
- LEACJMVNYZDSKR-UHFFFAOYSA-N 2-octyldodecan-1-ol Chemical compound CCCCCCCCCCC(CO)CCCCCCCC LEACJMVNYZDSKR-UHFFFAOYSA-N 0.000 claims description 5
- BTFJIXJJCSYFAL-UHFFFAOYSA-N arachidyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCO BTFJIXJJCSYFAL-UHFFFAOYSA-N 0.000 claims description 5
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 claims description 5
- WSSJONWNBBTCMG-UHFFFAOYSA-N 2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester Chemical compound C1C(C)(C)CC(C)CC1OC(=O)C1=CC=CC=C1O WSSJONWNBBTCMG-UHFFFAOYSA-N 0.000 claims description 4
- FMRHJJZUHUTGKE-UHFFFAOYSA-N Ethylhexyl salicylate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1O FMRHJJZUHUTGKE-UHFFFAOYSA-N 0.000 claims description 4
- IEZRNEGTKRQRFV-LFBNJJMOSA-N N-octadecanoyl-4-hydroxysphinganine Chemical compound CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)[C@H](O)CCCCCCCCCCCCCC IEZRNEGTKRQRFV-LFBNJJMOSA-N 0.000 claims description 4
- 150000001298 alcohols Chemical class 0.000 claims description 4
- 150000001335 aliphatic alkanes Chemical class 0.000 claims description 4
- XNEFYCZVKIDDMS-UHFFFAOYSA-N avobenzone Chemical compound C1=CC(OC)=CC=C1C(=O)CC(=O)C1=CC=C(C(C)(C)C)C=C1 XNEFYCZVKIDDMS-UHFFFAOYSA-N 0.000 claims description 4
- 229960005193 avobenzone Drugs 0.000 claims description 4
- OTKJDMGTUTTYMP-UHFFFAOYSA-N dihydrosphingosine Natural products CCCCCCCCCCCCCCCC(O)C(N)CO OTKJDMGTUTTYMP-UHFFFAOYSA-N 0.000 claims description 4
- 229940068171 ethyl hexyl salicylate Drugs 0.000 claims description 4
- 229960004881 homosalate Drugs 0.000 claims description 4
- FMJSMJQBSVNSBF-UHFFFAOYSA-N octocrylene Chemical group C=1C=CC=CC=1C(=C(C#N)C(=O)OCC(CC)CCCC)C1=CC=CC=C1 FMJSMJQBSVNSBF-UHFFFAOYSA-N 0.000 claims description 4
- 229960000601 octocrylene Drugs 0.000 claims description 4
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims description 4
- ROSDSFDQCJNGOL-UHFFFAOYSA-N protonated dimethyl amine Natural products CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 claims description 4
- 229960004889 salicylic acid Drugs 0.000 claims description 4
- 150000003626 triacylglycerols Chemical class 0.000 claims description 4
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 3
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims description 3
- LWIGVRDDANOFTD-UHFFFAOYSA-N hydroxy(dimethyl)silane Chemical group C[SiH](C)O LWIGVRDDANOFTD-UHFFFAOYSA-N 0.000 claims description 3
- XGMANDWIBKGABM-ZCXUNETKSA-N (z)-20-hydroxy-19-(hydroxymethyl)pentatriacont-9-en-18-one Chemical compound CCCCCCCCCCCCCCCC(O)C(CO)C(=O)CCCCCCC\C=C/CCCCCCCC XGMANDWIBKGABM-ZCXUNETKSA-N 0.000 claims description 2
- MJQIARGPQMNBGT-ZCXUNETKSA-N (z)-n-(1,3-dihydroxyoctadecan-2-yl)octadec-9-enamide Chemical compound CCCCCCCCCCCCCCCC(O)C(CO)NC(=O)CCCCCCC\C=C/CCCCCCCC MJQIARGPQMNBGT-ZCXUNETKSA-N 0.000 claims description 2
- 235000019198 oils Nutrition 0.000 description 91
- 150000002148 esters Chemical class 0.000 description 27
- 235000014113 dietary fatty acids Nutrition 0.000 description 25
- 229930195729 fatty acid Natural products 0.000 description 25
- 239000000194 fatty acid Substances 0.000 description 25
- 229920001296 polysiloxane Polymers 0.000 description 19
- 150000004665 fatty acids Chemical class 0.000 description 15
- 239000000693 micelle Substances 0.000 description 15
- 239000012071 phase Substances 0.000 description 15
- RMTFNDVZYPHUEF-XZBKPIIZSA-N 3-O-methyl-D-glucose Chemical compound O=C[C@H](O)[C@@H](OC)[C@H](O)[C@H](O)CO RMTFNDVZYPHUEF-XZBKPIIZSA-N 0.000 description 13
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 13
- 238000003756 stirring Methods 0.000 description 11
- ULUAUXLGCMPNKK-UHFFFAOYSA-N Sulfobutanedioic acid Chemical class OC(=O)CC(C(O)=O)S(O)(=O)=O ULUAUXLGCMPNKK-UHFFFAOYSA-N 0.000 description 9
- 238000002360 preparation method Methods 0.000 description 9
- 235000000346 sugar Nutrition 0.000 description 9
- 150000005690 diesters Chemical class 0.000 description 8
- 239000004615 ingredient Substances 0.000 description 8
- 229920006395 saturated elastomer Polymers 0.000 description 8
- XDOFQFKRPWOURC-UHFFFAOYSA-N 16-methylheptadecanoic acid Chemical compound CC(C)CCCCCCCCCCCCCCC(O)=O XDOFQFKRPWOURC-UHFFFAOYSA-N 0.000 description 7
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 7
- 125000004122 cyclic group Chemical group 0.000 description 7
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical class CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 7
- 239000008103 glucose Substances 0.000 description 7
- 150000002430 hydrocarbons Chemical class 0.000 description 7
- 239000007788 liquid Substances 0.000 description 7
- HOVAGTYPODGVJG-UHFFFAOYSA-N methyl beta-galactoside Natural products COC1OC(CO)C(O)C(O)C1O HOVAGTYPODGVJG-UHFFFAOYSA-N 0.000 description 7
- 238000002156 mixing Methods 0.000 description 7
- 229920006294 polydialkylsiloxane Polymers 0.000 description 7
- HOVAGTYPODGVJG-UVSYOFPXSA-N (3s,5r)-2-(hydroxymethyl)-6-methoxyoxane-3,4,5-triol Chemical compound COC1OC(CO)[C@@H](O)C(O)[C@H]1O HOVAGTYPODGVJG-UVSYOFPXSA-N 0.000 description 6
- OVSKIKFHRZPJSS-UHFFFAOYSA-N 2,4-D Chemical compound OC(=O)COC1=CC=C(Cl)C=C1Cl OVSKIKFHRZPJSS-UHFFFAOYSA-N 0.000 description 6
- BANXPJUEBPWEOT-UHFFFAOYSA-N 2-methyl-Pentadecane Chemical compound CCCCCCCCCCCCCC(C)C BANXPJUEBPWEOT-UHFFFAOYSA-N 0.000 description 6
- 239000002585 base Substances 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 6
- 238000002296 dynamic light scattering Methods 0.000 description 6
- 238000009472 formulation Methods 0.000 description 6
- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 6
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 5
- 235000021355 Stearic acid Nutrition 0.000 description 5
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 5
- 229930006000 Sucrose Natural products 0.000 description 5
- 125000002947 alkylene group Chemical group 0.000 description 5
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 5
- BLSNQVPBJDBAJJ-UHFFFAOYSA-L dipotassium;2-sulfobutanedioate Chemical compound [K+].[K+].OS(=O)(=O)C(C([O-])=O)CC([O-])=O BLSNQVPBJDBAJJ-UHFFFAOYSA-L 0.000 description 5
- 150000002170 ethers Chemical class 0.000 description 5
- 125000005456 glyceride group Chemical group 0.000 description 5
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 5
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 5
- HMMGMWAXVFQUOA-UHFFFAOYSA-N octamethylcyclotetrasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 HMMGMWAXVFQUOA-UHFFFAOYSA-N 0.000 description 5
- 239000005720 sucrose Substances 0.000 description 5
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 4
- 239000004264 Petrolatum Substances 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 4
- 239000010696 ester oil Substances 0.000 description 4
- XIRNKXNNONJFQO-UHFFFAOYSA-N ethyl hexadecanoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC XIRNKXNNONJFQO-UHFFFAOYSA-N 0.000 description 4
- 235000011187 glycerol Nutrition 0.000 description 4
- IPCSVZSSVZVIGE-UHFFFAOYSA-N n-hexadecanoic acid Natural products CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 4
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 4
- 229940066842 petrolatum Drugs 0.000 description 4
- 235000019271 petrolatum Nutrition 0.000 description 4
- 229920002545 silicone oil Polymers 0.000 description 4
- RYYKJJJTJZKILX-UHFFFAOYSA-M sodium octadecanoate Chemical class [Na+].CCCCCCCCCCCCCCCCCC([O-])=O RYYKJJJTJZKILX-UHFFFAOYSA-M 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 4
- 239000008117 stearic acid Substances 0.000 description 4
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 3
- 229940043268 2,2,4,4,6,8,8-heptamethylnonane Drugs 0.000 description 3
- MPNXSZJPSVBLHP-UHFFFAOYSA-N 2-chloro-n-phenylpyridine-3-carboxamide Chemical compound ClC1=NC=CC=C1C(=O)NC1=CC=CC=C1 MPNXSZJPSVBLHP-UHFFFAOYSA-N 0.000 description 3
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 3
- WQPMYSHJKXVTME-UHFFFAOYSA-N 3-hydroxypropane-1-sulfonic acid Chemical compound OCCCS(O)(=O)=O WQPMYSHJKXVTME-UHFFFAOYSA-N 0.000 description 3
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 3
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 3
- SNRUBQQJIBEYMU-UHFFFAOYSA-N Dodecane Natural products CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 description 3
- 239000005642 Oleic acid Substances 0.000 description 3
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 3
- 239000002202 Polyethylene glycol Substances 0.000 description 3
- PRXRUNOAOLTIEF-ADSICKODSA-N Sorbitan trioleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC[C@H](O)[C@H]1OC(=O)CCCCCCC\C=C/CCCCCCCC PRXRUNOAOLTIEF-ADSICKODSA-N 0.000 description 3
- 239000011149 active material Substances 0.000 description 3
- 150000001450 anions Chemical class 0.000 description 3
- 239000008346 aqueous phase Substances 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 235000019329 dioctyl sodium sulphosuccinate Nutrition 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 230000014509 gene expression Effects 0.000 description 3
- 150000002314 glycerols Chemical class 0.000 description 3
- 150000002500 ions Chemical class 0.000 description 3
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 3
- KUVMKLCGXIYSNH-UHFFFAOYSA-N isopentadecane Natural products CCCCCCCCCCCCC(C)C KUVMKLCGXIYSNH-UHFFFAOYSA-N 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 229940044591 methyl glucose dioleate Drugs 0.000 description 3
- JZMJDSHXVKJFKW-UHFFFAOYSA-M methyl sulfate(1-) Chemical compound COS([O-])(=O)=O JZMJDSHXVKJFKW-UHFFFAOYSA-M 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- 150000002942 palmitic acid derivatives Chemical class 0.000 description 3
- 239000002304 perfume Substances 0.000 description 3
- 229920001223 polyethylene glycol Polymers 0.000 description 3
- 229920005862 polyol Polymers 0.000 description 3
- 150000003077 polyols Chemical class 0.000 description 3
- CACRHRQTJDKAPJ-UHFFFAOYSA-M potassium;1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate Chemical compound [K+].CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC CACRHRQTJDKAPJ-UHFFFAOYSA-M 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 150000008163 sugars Chemical class 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- GFAZGHREJPXDMH-UHFFFAOYSA-N 1,3-dipalmitoylglycerol Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(O)COC(=O)CCCCCCCCCCCCCCC GFAZGHREJPXDMH-UHFFFAOYSA-N 0.000 description 2
- ICAXUQIEOXHXKK-UHFFFAOYSA-N 1,4-dioxo-1,4-di(tridecoxy)butane-2-sulfonic acid Chemical compound CCCCCCCCCCCCCOC(=O)CC(S(O)(=O)=O)C(=O)OCCCCCCCCCCCCC ICAXUQIEOXHXKK-UHFFFAOYSA-N 0.000 description 2
- LTSWUFKUZPPYEG-UHFFFAOYSA-N 1-decoxydecane Chemical compound CCCCCCCCCCOCCCCCCCCCC LTSWUFKUZPPYEG-UHFFFAOYSA-N 0.000 description 2
- CMCBDXRRFKYBDG-UHFFFAOYSA-N 1-dodecoxydodecane Chemical compound CCCCCCCCCCCCOCCCCCCCCCCCC CMCBDXRRFKYBDG-UHFFFAOYSA-N 0.000 description 2
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 2
- LGEZTMRIZWCDLW-UHFFFAOYSA-N 14-methylpentadecyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCC(C)C LGEZTMRIZWCDLW-UHFFFAOYSA-N 0.000 description 2
- MQFYRUGXOJAUQK-UHFFFAOYSA-N 2-[2-[2-(2-octadecanoyloxyethoxy)ethoxy]ethoxy]ethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCOCCOCCOCCOC(=O)CCCCCCCCCCCCCCCCC MQFYRUGXOJAUQK-UHFFFAOYSA-N 0.000 description 2
- ZVUNTIMPQCQCAQ-UHFFFAOYSA-N 2-dodecanoyloxyethyl dodecanoate Chemical compound CCCCCCCCCCCC(=O)OCCOC(=O)CCCCCCCCCCC ZVUNTIMPQCQCAQ-UHFFFAOYSA-N 0.000 description 2
- LEEDMQGKBNGPDN-UHFFFAOYSA-N 2-methylnonadecane Chemical compound CCCCCCCCCCCCCCCCCC(C)C LEEDMQGKBNGPDN-UHFFFAOYSA-N 0.000 description 2
- UIVPNOBLHXUKDX-UHFFFAOYSA-N 3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate Chemical compound CC(C)(C)CC(C)CCOC(=O)CC(C)CC(C)(C)C UIVPNOBLHXUKDX-UHFFFAOYSA-N 0.000 description 2
- HBTAOSGHCXUEKI-UHFFFAOYSA-N 4-chloro-n,n-dimethyl-3-nitrobenzenesulfonamide Chemical compound CN(C)S(=O)(=O)C1=CC=C(Cl)C([N+]([O-])=O)=C1 HBTAOSGHCXUEKI-UHFFFAOYSA-N 0.000 description 2
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 2
- KGKQNDQDVZQTAG-UHFFFAOYSA-N 8-methylnonyl 2,2-dimethylpropanoate Chemical compound CC(C)CCCCCCCOC(=O)C(C)(C)C KGKQNDQDVZQTAG-UHFFFAOYSA-N 0.000 description 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 2
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 2
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 description 2
- IUMSDRXLFWAGNT-UHFFFAOYSA-N Dodecamethylcyclohexasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 IUMSDRXLFWAGNT-UHFFFAOYSA-N 0.000 description 2
- 239000005639 Lauric acid Substances 0.000 description 2
- FLIACVVOZYBSBS-UHFFFAOYSA-N Methyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC FLIACVVOZYBSBS-UHFFFAOYSA-N 0.000 description 2
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 description 2
- 235000021314 Palmitic acid Nutrition 0.000 description 2
- OQILCOQZDHPEAZ-UHFFFAOYSA-N Palmitinsaeure-octylester Natural products CCCCCCCCCCCCCCCC(=O)OCCCCCCCC OQILCOQZDHPEAZ-UHFFFAOYSA-N 0.000 description 2
- NKSOSPOXQKNIKJ-CLFAGFIQSA-N Polyoxyethylene dioleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCCOC(=O)CCCCCCC\C=C/CCCCCCCC NKSOSPOXQKNIKJ-CLFAGFIQSA-N 0.000 description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical group [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 2
- 239000004147 Sorbitan trioleate Substances 0.000 description 2
- IJCWFDPJFXGQBN-RYNSOKOISA-N [(2R)-2-[(2R,3R,4S)-4-hydroxy-3-octadecanoyloxyoxolan-2-yl]-2-octadecanoyloxyethyl] octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCCCCCCCCCCCC)[C@H]1OC[C@H](O)[C@H]1OC(=O)CCCCCCCCCCCCCCCCC IJCWFDPJFXGQBN-RYNSOKOISA-N 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 125000001931 aliphatic group Chemical group 0.000 description 2
- 229910052783 alkali metal Inorganic materials 0.000 description 2
- 239000002280 amphoteric surfactant Substances 0.000 description 2
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 2
- 125000003118 aryl group Chemical group 0.000 description 2
- 125000002511 behenyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 2
- ZFMQKOWCDKKBIF-UHFFFAOYSA-N bis(3,5-difluorophenyl)phosphane Chemical compound FC1=CC(F)=CC(PC=2C=C(F)C=C(F)C=2)=C1 ZFMQKOWCDKKBIF-UHFFFAOYSA-N 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 2
- 229940028820 didecyl ether Drugs 0.000 description 2
- ZCPCLAPUXMZUCD-UHFFFAOYSA-M dihexadecyl(dimethyl)azanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCC ZCPCLAPUXMZUCD-UHFFFAOYSA-M 0.000 description 2
- 229940031578 diisopropyl adipate Drugs 0.000 description 2
- PKPOVTYZGGYDIJ-UHFFFAOYSA-N dioctyl carbonate Chemical compound CCCCCCCCOC(=O)OCCCCCCCC PKPOVTYZGGYDIJ-UHFFFAOYSA-N 0.000 description 2
- NOLXQSVNNIIHMV-UHFFFAOYSA-L disodium;2,2-diethyl-3-hexyl-3-sulfobutanedioate Chemical compound [Na+].[Na+].CCCCCCC(C([O-])=O)(S(O)(=O)=O)C(CC)(CC)C([O-])=O NOLXQSVNNIIHMV-UHFFFAOYSA-L 0.000 description 2
- YHAIUSTWZPMYGG-UHFFFAOYSA-L disodium;2,2-dioctyl-3-sulfobutanedioate Chemical compound [Na+].[Na+].CCCCCCCCC(C([O-])=O)(C(C([O-])=O)S(O)(=O)=O)CCCCCCCC YHAIUSTWZPMYGG-UHFFFAOYSA-L 0.000 description 2
- JMGZBMRVDHKMKB-UHFFFAOYSA-L disodium;2-sulfobutanedioate Chemical compound [Na+].[Na+].OS(=O)(=O)C(C([O-])=O)CC([O-])=O JMGZBMRVDHKMKB-UHFFFAOYSA-L 0.000 description 2
- UKMSUNONTOPOIO-UHFFFAOYSA-N docosanoic acid Chemical compound CCCCCCCCCCCCCCCCCCCCCC(O)=O UKMSUNONTOPOIO-UHFFFAOYSA-N 0.000 description 2
- MMXKVMNBHPAILY-UHFFFAOYSA-N ethyl laurate Chemical compound CCCCCCCCCCCC(=O)OCC MMXKVMNBHPAILY-UHFFFAOYSA-N 0.000 description 2
- MMKRHZKQPFCLLS-UHFFFAOYSA-N ethyl myristate Chemical compound CCCCCCCCCCCCCC(=O)OCC MMKRHZKQPFCLLS-UHFFFAOYSA-N 0.000 description 2
- 229940067592 ethyl palmitate Drugs 0.000 description 2
- GJQLBGWSDGMZKM-UHFFFAOYSA-N ethylhexyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(CC)CCCCC GJQLBGWSDGMZKM-UHFFFAOYSA-N 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 229920006007 hydrogenated polyisobutylene Polymers 0.000 description 2
- 229940078545 isocetyl stearate Drugs 0.000 description 2
- 229940100554 isononyl isononanoate Drugs 0.000 description 2
- 229940115478 isopropyl lauroyl sarcosinate Drugs 0.000 description 2
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 description 2
- 229940057995 liquid paraffin Drugs 0.000 description 2
- 239000000178 monomer Substances 0.000 description 2
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 2
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 2
- CRSOQBOWXPBRES-UHFFFAOYSA-N neopentane Chemical compound CC(C)(C)C CRSOQBOWXPBRES-UHFFFAOYSA-N 0.000 description 2
- KSCKTBJJRVPGKM-UHFFFAOYSA-N octan-1-olate;titanium(4+) Chemical compound [Ti+4].CCCCCCCC[O-].CCCCCCCC[O-].CCCCCCCC[O-].CCCCCCCC[O-] KSCKTBJJRVPGKM-UHFFFAOYSA-N 0.000 description 2
- 150000003904 phospholipids Chemical class 0.000 description 2
- XLCIFRJORZNGEV-UHFFFAOYSA-N propan-2-yl 2-[dodecanoyl(methyl)amino]acetate Chemical compound CCCCCCCCCCCC(=O)N(C)CC(=O)OC(C)C XLCIFRJORZNGEV-UHFFFAOYSA-N 0.000 description 2
- 235000019337 sorbitan trioleate Nutrition 0.000 description 2
- 229960000391 sorbitan trioleate Drugs 0.000 description 2
- 235000011078 sorbitan tristearate Nutrition 0.000 description 2
- 229940032094 squalane Drugs 0.000 description 2
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- 125000000542 sulfonic acid group Chemical group 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 229920001897 terpolymer Polymers 0.000 description 2
- TUNFSRHWOTWDNC-UHFFFAOYSA-N tetradecanoic acid Chemical class CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 description 2
- 150000003628 tricarboxylic acids Chemical class 0.000 description 2
- IIYFAKIEWZDVMP-UHFFFAOYSA-N tridecane Chemical compound CCCCCCCCCCCCC IIYFAKIEWZDVMP-UHFFFAOYSA-N 0.000 description 2
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 2
- UUJLHYCIMQOUKC-UHFFFAOYSA-N trimethyl-[oxo(trimethylsilylperoxy)silyl]peroxysilane Chemical compound C[Si](C)(C)OO[Si](=O)OO[Si](C)(C)C UUJLHYCIMQOUKC-UHFFFAOYSA-N 0.000 description 2
- PVNIQBQSYATKKL-UHFFFAOYSA-N tripalmitin Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCC PVNIQBQSYATKKL-UHFFFAOYSA-N 0.000 description 2
- DCXXMTOCNZCJGO-UHFFFAOYSA-N tristearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC DCXXMTOCNZCJGO-UHFFFAOYSA-N 0.000 description 2
- RSJKGSCJYJTIGS-UHFFFAOYSA-N undecane Chemical compound CCCCCCCCCCC RSJKGSCJYJTIGS-UHFFFAOYSA-N 0.000 description 2
- 235000015112 vegetable and seed oil Nutrition 0.000 description 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 description 1
- OQQOAWVKVDAJOI-UHFFFAOYSA-N (2-dodecanoyloxy-3-hydroxypropyl) dodecanoate Chemical compound CCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCCCCCC OQQOAWVKVDAJOI-UHFFFAOYSA-N 0.000 description 1
- NRTKYSGFUISGRQ-UHFFFAOYSA-N (3-heptanoyloxy-2,2-dimethylpropyl) heptanoate Chemical compound CCCCCCC(=O)OCC(C)(C)COC(=O)CCCCCC NRTKYSGFUISGRQ-UHFFFAOYSA-N 0.000 description 1
- IJPCXCDDMAUNSI-ULAWRXDQSA-N (4r,5s,6r,7r)-4,5,6,7,8-pentahydroxyoctan-3-one Chemical compound CCC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO IJPCXCDDMAUNSI-ULAWRXDQSA-N 0.000 description 1
- AFSHUZFNMVJNKX-UHFFFAOYSA-N 1,2-di-(9Z-octadecenoyl)glycerol Natural products CCCCCCCCC=CCCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCCC=CCCCCCCCC AFSHUZFNMVJNKX-UHFFFAOYSA-N 0.000 description 1
- AFSHUZFNMVJNKX-LLWMBOQKSA-N 1,2-dioleoyl-sn-glycerol Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCC\C=C/CCCCCCCC AFSHUZFNMVJNKX-LLWMBOQKSA-N 0.000 description 1
- MHUWZNTUIIFHAS-DSSVUWSHSA-N 1,2-dioleoyl-sn-glycerol-3-phosphate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP(O)(O)=O)OC(=O)CCCCCCC\C=C/CCCCCCCC MHUWZNTUIIFHAS-DSSVUWSHSA-N 0.000 description 1
- PYRVOLKVRLTFNA-UHFFFAOYSA-N 1,3-didecoxypropan-2-ol Chemical compound CCCCCCCCCCOCC(O)COCCCCCCCCCC PYRVOLKVRLTFNA-UHFFFAOYSA-N 0.000 description 1
- JDAFESMYZWVKEQ-UHFFFAOYSA-N 1,3-didodecoxypropan-2-ol Chemical compound CCCCCCCCCCCCOCC(O)COCCCCCCCCCCCC JDAFESMYZWVKEQ-UHFFFAOYSA-N 0.000 description 1
- RBGYBTJRVDFANH-UHFFFAOYSA-N 1,3-dioctoxypropan-2-ol Chemical compound CCCCCCCCOCC(O)COCCCCCCCC RBGYBTJRVDFANH-UHFFFAOYSA-N 0.000 description 1
- QPSVFNQMURAADJ-UHFFFAOYSA-N 1,4-dicyclohexyloxy-1,4-dioxobutane-2-sulfonic acid Chemical compound C1CCCCC1OC(=O)C(S(=O)(=O)O)CC(=O)OC1CCCCC1 QPSVFNQMURAADJ-UHFFFAOYSA-N 0.000 description 1
- OMMMUWNDGQFGDV-UHFFFAOYSA-N 1,4-didodecoxy-1,4-dioxobutane-2-sulfonic acid Chemical compound CCCCCCCCCCCCOC(=O)CC(S(O)(=O)=O)C(=O)OCCCCCCCCCCCC OMMMUWNDGQFGDV-UHFFFAOYSA-N 0.000 description 1
- UTWVENOYOROSRG-UHFFFAOYSA-N 1,4-didodecoxy-1,4-dioxobutane-2-sulfonic acid;sodium Chemical compound [Na].CCCCCCCCCCCCOC(=O)CC(S(O)(=O)=O)C(=O)OCCCCCCCCCCCC UTWVENOYOROSRG-UHFFFAOYSA-N 0.000 description 1
- XPOAKONDJSMGSB-UHFFFAOYSA-N 1,4-dioxo-1,4-di(undecoxy)butane-2-sulfonic acid;sodium Chemical compound [Na].CCCCCCCCCCCOC(=O)CC(S(O)(=O)=O)C(=O)OCCCCCCCCCCC XPOAKONDJSMGSB-UHFFFAOYSA-N 0.000 description 1
- CZWWITYVYJRTOX-UHFFFAOYSA-N 1-(2-methylpropoxy)hexadecane Chemical compound CCCCCCCCCCCCCCCCOCC(C)C CZWWITYVYJRTOX-UHFFFAOYSA-N 0.000 description 1
- XMFUMMRWIFOQDQ-UHFFFAOYSA-N 1-(4-methylpentan-2-yloxy)hexadecane Chemical compound CCCCCCCCCCCCCCCCOC(C)CC(C)C XMFUMMRWIFOQDQ-UHFFFAOYSA-N 0.000 description 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- ULQISTXYYBZJSJ-UHFFFAOYSA-N 12-hydroxyoctadecanoic acid Chemical compound CCCCCCC(O)CCCCCCCCCCC(O)=O ULQISTXYYBZJSJ-UHFFFAOYSA-N 0.000 description 1
- JSOVGYMVTPPEND-UHFFFAOYSA-N 16-methylheptadecyl 2,2-dimethylpropanoate Chemical compound CC(C)CCCCCCCCCCCCCCCOC(=O)C(C)(C)C JSOVGYMVTPPEND-UHFFFAOYSA-N 0.000 description 1
- XYTHHAXRVHHXKO-JIUYZRCGSA-N 18-[(2r,3s,4r,5r)-4,5-dihydroxy-2-(hydroxymethyl)-6-methoxyoxan-3-yl]oxyoctadecanoic acid;ethanol Chemical compound CCO.COC1O[C@H](CO)[C@@H](OCCCCCCCCCCCCCCCCCC(O)=O)[C@H](O)[C@H]1O XYTHHAXRVHHXKO-JIUYZRCGSA-N 0.000 description 1
- QFZKSWMAYXNSEJ-UHFFFAOYSA-N 2,3-bis(2-hydroxypropanoyloxy)propyl 2-hydroxypropanoate Chemical compound CC(O)C(=O)OCC(OC(=O)C(C)O)COC(=O)C(C)O QFZKSWMAYXNSEJ-UHFFFAOYSA-N 0.000 description 1
- KWVJHCQQUFDPLU-YEUCEMRASA-N 2,3-bis[[(z)-octadec-9-enoyl]oxy]propyl-trimethylazanium Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(C[N+](C)(C)C)OC(=O)CCCCCCC\C=C/CCCCCCCC KWVJHCQQUFDPLU-YEUCEMRASA-N 0.000 description 1
- FZGBADVTTLOFPU-UHFFFAOYSA-N 2-(2-dodecanoyloxyethoxy)ethyl dodecanoate Chemical compound CCCCCCCCCCCC(=O)OCCOCCOC(=O)CCCCCCCCCCC FZGBADVTTLOFPU-UHFFFAOYSA-N 0.000 description 1
- OBETXYAYXDNJHR-UHFFFAOYSA-N 2-Ethylhexanoic acid Chemical compound CCCCC(CC)C(O)=O OBETXYAYXDNJHR-UHFFFAOYSA-N 0.000 description 1
- KIHBGTRZFAVZRV-UHFFFAOYSA-N 2-Hydroxyoctadecanoic acid Natural products CCCCCCCCCCCCCCCCC(O)C(O)=O KIHBGTRZFAVZRV-UHFFFAOYSA-N 0.000 description 1
- YBRJTUFWBLSLHY-UHFFFAOYSA-N 2-[2-(2-octadecanoyloxyethoxy)ethoxy]ethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCOCCOCCOC(=O)CCCCCCCCCCCCCCCCC YBRJTUFWBLSLHY-UHFFFAOYSA-N 0.000 description 1
- FWIUBOWVXREPPL-UHFFFAOYSA-N 2-[2-(7-methyloctanoyloxy)ethoxy]ethyl 7-methyloctanoate Chemical compound CC(C)CCCCCC(=O)OCCOCCOC(=O)CCCCCC(C)C FWIUBOWVXREPPL-UHFFFAOYSA-N 0.000 description 1
- IFWVXSTYAPCLGQ-CLFAGFIQSA-N 2-[2-[2-[(Z)-octadec-9-enoyl]oxyethoxy]ethoxy]ethyl (Z)-octadec-9-enoate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCCOCCOCCOC(=O)CCCCCCC\C=C/CCCCCCCC IFWVXSTYAPCLGQ-CLFAGFIQSA-N 0.000 description 1
- TWJNQYPJQDRXPH-UHFFFAOYSA-N 2-cyanobenzohydrazide Chemical compound NNC(=O)C1=CC=CC=C1C#N TWJNQYPJQDRXPH-UHFFFAOYSA-N 0.000 description 1
- OUCGJMIVSYHBEC-UHFFFAOYSA-N 2-ethylhexyl 2-ethylhexanoate Chemical compound CCCCC(CC)COC(=O)C(CC)CCCC OUCGJMIVSYHBEC-UHFFFAOYSA-N 0.000 description 1
- NAGVKZOTMXGCCA-UHFFFAOYSA-N 2-ethylhexyl 7-methyloctanoate Chemical compound CCCCC(CC)COC(=O)CCCCCC(C)C NAGVKZOTMXGCCA-UHFFFAOYSA-N 0.000 description 1
- HPUAIVNIHNEYPO-UHFFFAOYSA-N 2-ethylhexyl octanoate Chemical compound CCCCCCCC(=O)OCC(CC)CCCC HPUAIVNIHNEYPO-UHFFFAOYSA-N 0.000 description 1
- IZHVBANLECCAGF-UHFFFAOYSA-N 2-hydroxy-3-(octadecanoyloxy)propyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)COC(=O)CCCCCCCCCCCCCCCCC IZHVBANLECCAGF-UHFFFAOYSA-N 0.000 description 1
- CDOUZKKFHVEKRI-UHFFFAOYSA-N 3-bromo-n-[(prop-2-enoylamino)methyl]propanamide Chemical compound BrCCC(=O)NCNC(=O)C=C CDOUZKKFHVEKRI-UHFFFAOYSA-N 0.000 description 1
- YSLMWMWTFSOPFR-UHFFFAOYSA-N 3-ethyl-2-(3-ethyl-2-methylpentadecan-2-yl)oxy-2-methylpentadecane Chemical compound C(CCCCCCCCCCC)C(C(C)(C)OC(C(CC)CCCCCCCCCCCC)(C)C)CC YSLMWMWTFSOPFR-UHFFFAOYSA-N 0.000 description 1
- 125000003469 3-methylhexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])* 0.000 description 1
- ZQXRINMCMHCYBD-UHFFFAOYSA-N 4-(2-ethylhexoxy)-4-oxobutanoic acid Chemical compound CCCCC(CC)COC(=O)CCC(O)=O ZQXRINMCMHCYBD-UHFFFAOYSA-N 0.000 description 1
- IBYCEACZVUOBIV-UHFFFAOYSA-N 4-methylpentyl dodecanoate Chemical compound CCCCCCCCCCCC(=O)OCCCC(C)C IBYCEACZVUOBIV-UHFFFAOYSA-N 0.000 description 1
- ODMZDMMTKHXXKA-QXMHVHEDSA-N 8-methylnonyl (z)-octadec-9-enoate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCCCCCCCC(C)C ODMZDMMTKHXXKA-QXMHVHEDSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 235000019489 Almond oil Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- 235000017060 Arachis glabrata Nutrition 0.000 description 1
- 244000105624 Arachis hypogaea Species 0.000 description 1
- 235000010777 Arachis hypogaea Nutrition 0.000 description 1
- 235000018262 Arachis monticola Nutrition 0.000 description 1
- 235000021357 Behenic acid Nutrition 0.000 description 1
- LSAACDIRVQTDAU-UHFFFAOYSA-N C(CC(O)(C(=O)O)CC(=O)O)(=O)O.C(CCCCCCC)C(CCCCCCCCCCC)O.C(CCCCCCC)C(CCCCCCCCCCC)O.C(CCCCCCC)C(CCCCCCCCCCC)O Chemical compound C(CC(O)(C(=O)O)CC(=O)O)(=O)O.C(CCCCCCC)C(CCCCCCCCCCC)O.C(CCCCCCC)C(CCCCCCCCCCC)O.C(CCCCCCC)C(CCCCCCCCCCC)O LSAACDIRVQTDAU-UHFFFAOYSA-N 0.000 description 1
- IPPBLYQHJFXJGG-UHFFFAOYSA-N C[Si](C)(C)C(C(C(O)[Si](C)(C)C)(C(O)[Si](C)(C)C)C(O)[Si](C)(C)C)O Chemical compound C[Si](C)(C)C(C(C(O)[Si](C)(C)C)(C(O)[Si](C)(C)C)C(O)[Si](C)(C)C)O IPPBLYQHJFXJGG-UHFFFAOYSA-N 0.000 description 1
- 240000001548 Camellia japonica Species 0.000 description 1
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 description 1
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 description 1
- CXRFDZFCGOPDTD-UHFFFAOYSA-M Cetrimide Chemical compound [Br-].CCCCCCCCCCCCCC[N+](C)(C)C CXRFDZFCGOPDTD-UHFFFAOYSA-M 0.000 description 1
- LZZYPRNAOMGNLH-UHFFFAOYSA-M Cetrimonium bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C LZZYPRNAOMGNLH-UHFFFAOYSA-M 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 description 1
- HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 description 1
- NKOUWLLFHNBUDW-UHFFFAOYSA-N Dipropyl hexanedioate Chemical compound CCCOC(=O)CCCCC(=O)OCCC NKOUWLLFHNBUDW-UHFFFAOYSA-N 0.000 description 1
- KIWBPDUYBMNFTB-UHFFFAOYSA-N Ethyl hydrogen sulfate Chemical compound CCOS(O)(=O)=O KIWBPDUYBMNFTB-UHFFFAOYSA-N 0.000 description 1
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 1
- FPVVYTCTZKCSOJ-UHFFFAOYSA-N Ethylene glycol distearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCOC(=O)CCCCCCCCCCCCCCCCC FPVVYTCTZKCSOJ-UHFFFAOYSA-N 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- CMBYOWLFQAFZCP-UHFFFAOYSA-N Hexyl dodecanoate Chemical compound CCCCCCCCCCCC(=O)OCCCCCC CMBYOWLFQAFZCP-UHFFFAOYSA-N 0.000 description 1
- SHBUUTHKGIVMJT-UHFFFAOYSA-N Hydroxystearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OO SHBUUTHKGIVMJT-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 235000018330 Macadamia integrifolia Nutrition 0.000 description 1
- 240000000912 Macadamia tetraphylla Species 0.000 description 1
- 235000003800 Macadamia tetraphylla Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- BAVYZALUXZFZLV-UHFFFAOYSA-O Methylammonium ion Chemical compound [NH3+]C BAVYZALUXZFZLV-UHFFFAOYSA-O 0.000 description 1
- 235000021360 Myristic acid Nutrition 0.000 description 1
- 229910002651 NO3 Inorganic materials 0.000 description 1
- 241000772415 Neovison vison Species 0.000 description 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 235000019483 Peanut oil Nutrition 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 229920001213 Polysorbate 20 Polymers 0.000 description 1
- 229920001214 Polysorbate 60 Polymers 0.000 description 1
- 229920002651 Polysorbate 85 Polymers 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 235000019484 Rapeseed oil Nutrition 0.000 description 1
- PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 description 1
- SVNZSBZSOACERS-UHFFFAOYSA-N S(=O)(=O)(O)C(C(=O)O)CC(=O)O.C(C)C(CCCCC)([K])CC Chemical compound S(=O)(=O)(O)C(C(=O)O)CC(=O)O.C(C)C(CCCCC)([K])CC SVNZSBZSOACERS-UHFFFAOYSA-N 0.000 description 1
- ZHLFMFUKDZXWJG-UHFFFAOYSA-N S(=O)(=O)(O)C(C(=O)OC(CCCCC)(CC)CC)CC(=O)[O-].[NH4+] Chemical compound S(=O)(=O)(O)C(C(=O)OC(CCCCC)(CC)CC)CC(=O)[O-].[NH4+] ZHLFMFUKDZXWJG-UHFFFAOYSA-N 0.000 description 1
- BJYVSHDIPHRDQR-UHFFFAOYSA-N S(=O)(=O)(O)C(C(=O)OCCCCCCC(C)C)CC(=O)OCCCCCCC(C)C.[Na] Chemical compound S(=O)(=O)(O)C(C(=O)OCCCCCCC(C)C)CC(=O)OCCCCCCC(C)C.[Na] BJYVSHDIPHRDQR-UHFFFAOYSA-N 0.000 description 1
- VVHXKSALMOCGBH-UHFFFAOYSA-N S(=O)(=O)(O)C(C(=O)OCCCCCCCCCCC)CC(=O)OCCCCCCCCCCC.[K] Chemical compound S(=O)(=O)(O)C(C(=O)OCCCCCCCCCCC)CC(=O)OCCCCCCCCCCC.[K] VVHXKSALMOCGBH-UHFFFAOYSA-N 0.000 description 1
- MLARMLHKXIDRFC-UHFFFAOYSA-N S(=O)(=O)(O)C(C(=O)[O-])CC(=O)[O-].C(CC)[NH+](CCCCCCC)CCC.C(CC)[NH+](CCC)CCCCCCC Chemical compound S(=O)(=O)(O)C(C(=O)[O-])CC(=O)[O-].C(CC)[NH+](CCCCCCC)CCC.C(CC)[NH+](CCC)CCCCCCC MLARMLHKXIDRFC-UHFFFAOYSA-N 0.000 description 1
- LSEWYXCITQPPSB-UHFFFAOYSA-N S(=O)(=O)(O)C(C(=O)[O-])CC(=O)[O-].C(CCCCCC)[NH2+]CCCCCCC.C(CCCCCC)[NH2+]CCCCCCC Chemical compound S(=O)(=O)(O)C(C(=O)[O-])CC(=O)[O-].C(CCCCCC)[NH2+]CCCCCCC.C(CCCCCC)[NH2+]CCCCCCC LSEWYXCITQPPSB-UHFFFAOYSA-N 0.000 description 1
- MDXZUJDTLBJGBU-UHFFFAOYSA-N S(=O)(=O)(O)C(C(=O)[O-])CC(=O)[O-].C(CCCCCCCCC)[NH2+]CCCCCCCCCC.C(CCCCCCCCC)[NH2+]CCCCCCCCCC Chemical compound S(=O)(=O)(O)C(C(=O)[O-])CC(=O)[O-].C(CCCCCCCCC)[NH2+]CCCCCCCCCC.C(CCCCCCCCC)[NH2+]CCCCCCCCCC MDXZUJDTLBJGBU-UHFFFAOYSA-N 0.000 description 1
- PFVGKAYNIXFQHC-UHFFFAOYSA-N S(=O)(=O)(O)C(C(=O)[O-])CC(=O)[O-].C(CCCCCCCCCCCC)[NH2+]CCCCCCCCCCCCC.C(CCCCCCCCCCCC)[NH2+]CCCCCCCCCCCCC Chemical compound S(=O)(=O)(O)C(C(=O)[O-])CC(=O)[O-].C(CCCCCCCCCCCC)[NH2+]CCCCCCCCCCCCC.C(CCCCCCCCCCCC)[NH2+]CCCCCCCCCCCCC PFVGKAYNIXFQHC-UHFFFAOYSA-N 0.000 description 1
- IKHPYSYXWZPSHL-UHFFFAOYSA-N S(=O)(=O)(O)C(C(=O)[O-])CC(=O)[O-].C1(CCCCC1)[NH2+]C1CCCCC1.C1(CCCCC1)[NH2+]C1CCCCC1 Chemical compound S(=O)(=O)(O)C(C(=O)[O-])CC(=O)[O-].C1(CCCCC1)[NH2+]C1CCCCC1.C1(CCCCC1)[NH2+]C1CCCCC1 IKHPYSYXWZPSHL-UHFFFAOYSA-N 0.000 description 1
- 235000019485 Safflower oil Nutrition 0.000 description 1
- VBIIFPGSPJYLRR-UHFFFAOYSA-M Stearyltrimethylammonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCCCC[N+](C)(C)C VBIIFPGSPJYLRR-UHFFFAOYSA-M 0.000 description 1
- 235000019486 Sunflower oil Nutrition 0.000 description 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 description 1
- XSTXAVWGXDQKEL-UHFFFAOYSA-N Trichloroethylene Chemical compound ClC=C(Cl)Cl XSTXAVWGXDQKEL-UHFFFAOYSA-N 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- 239000004904 UV filter Substances 0.000 description 1
- HLLPKVARTYKIJB-MCQPFKOBSA-N [(2r,3s,4s,5r,6r)-6-[(2s,3s,4s,5r)-3,4-dihydroxy-2,5-bis(octadecanoyloxymethyl)oxolan-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl octadecanoate Chemical compound O[C@H]1[C@H](O)[C@@H](COC(=O)CCCCCCCCCCCCCCCCC)O[C@@]1(COC(=O)CCCCCCCCCCCCCCCCC)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](COC(=O)CCCCCCCCCCCCCCCCC)O1 HLLPKVARTYKIJB-MCQPFKOBSA-N 0.000 description 1
- NJWPTAJOXLJZHJ-XQAXEFKXSA-N [(2s,3s,4r,5r)-3,4-di(dodecanoyloxy)-5-(hydroxymethyl)-2-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-yl]methyl dodecanoate Chemical compound O([C@@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@]1(COC(=O)CCCCCCCCCCC)O[C@H](CO)[C@@H](OC(=O)CCCCCCCCCCC)[C@@H]1OC(=O)CCCCCCCCCCC NJWPTAJOXLJZHJ-XQAXEFKXSA-N 0.000 description 1
- OCRUMFQGIMSFJR-FSAWCSQFSA-N [(2s,3s,4r,5r)-4-hydroxy-5-(hydroxymethyl)-3-[(z)-octadec-9-enoyl]oxy-2-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-yl]methyl (z)-octadec-9-enoate Chemical compound O([C@@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@]1(COC(=O)CCCCCCC\C=C/CCCCCCCC)O[C@H](CO)[C@@H](O)[C@@H]1OC(=O)CCCCCCC\C=C/CCCCCCCC OCRUMFQGIMSFJR-FSAWCSQFSA-N 0.000 description 1
- VFCBYFDYBODXCH-YGWGHPONSA-N [(2s,3s,4r,5r)-5-(hydroxymethyl)-3,4-bis[[(z)-octadec-9-enoyl]oxy]-2-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-yl]methyl (z)-octadec-9-enoate Chemical compound O([C@@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@]1(COC(=O)CCCCCCC\C=C/CCCCCCCC)O[C@H](CO)[C@@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)[C@@H]1OC(=O)CCCCCCC\C=C/CCCCCCCC VFCBYFDYBODXCH-YGWGHPONSA-N 0.000 description 1
- DRRMRHKHTQRWMB-UHFFFAOYSA-N [3-(2-ethylhexanoyloxy)-2,2-bis(2-ethylhexanoyloxymethyl)propyl] 2-ethylhexanoate Chemical compound CCCCC(CC)C(=O)OCC(COC(=O)C(CC)CCCC)(COC(=O)C(CC)CCCC)COC(=O)C(CC)CCCC DRRMRHKHTQRWMB-UHFFFAOYSA-N 0.000 description 1
- YFCGDEUVHLPRCZ-UHFFFAOYSA-N [dimethyl(trimethylsilyloxy)silyl]oxy-dimethyl-trimethylsilyloxysilane Chemical group C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C YFCGDEUVHLPRCZ-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 125000003158 alcohol group Chemical group 0.000 description 1
- 150000001299 aldehydes Chemical class 0.000 description 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 1
- 125000005211 alkyl trimethyl ammonium group Chemical group 0.000 description 1
- 239000008168 almond oil Substances 0.000 description 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 description 1
- HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 description 1
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical class CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 description 1
- 125000001204 arachidyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 235000021302 avocado oil Nutrition 0.000 description 1
- 239000008163 avocado oil Substances 0.000 description 1
- PIKODYZXFHKWFW-UHFFFAOYSA-N azanium;1,4-di(nonoxy)-1,4-dioxobutane-2-sulfonate Chemical compound N.CCCCCCCCCOC(=O)CC(S(O)(=O)=O)C(=O)OCCCCCCCCC PIKODYZXFHKWFW-UHFFFAOYSA-N 0.000 description 1
- NHNBRUZMOBULPD-UHFFFAOYSA-N azanium;4-hydroxy-4-oxo-3-sulfobutanoate Chemical compound N.OC(=O)CC(C(O)=O)S(O)(=O)=O NHNBRUZMOBULPD-UHFFFAOYSA-N 0.000 description 1
- 229940116226 behenic acid Drugs 0.000 description 1
- YSJGOMATDFSEED-UHFFFAOYSA-M behentrimonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCCCCCCCC[N+](C)(C)C YSJGOMATDFSEED-UHFFFAOYSA-M 0.000 description 1
- QBEUXDWEKIOSIL-UHFFFAOYSA-N benzyl 5-amino-1h-pyrazole-4-carboxylate Chemical compound N1N=CC(C(=O)OCC=2C=CC=CC=2)=C1N QBEUXDWEKIOSIL-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
- GFRHRWJBYWRSJE-UHFFFAOYSA-N bis(16-methylheptadecyl) hexanedioate Chemical compound CC(C)CCCCCCCCCCCCCCCOC(=O)CCCCC(=O)OCCCCCCCCCCCCCCCC(C)C GFRHRWJBYWRSJE-UHFFFAOYSA-N 0.000 description 1
- ROPXFXOUUANXRR-YPKPFQOOSA-N bis(2-ethylhexyl) (z)-but-2-enedioate Chemical compound CCCCC(CC)COC(=O)\C=C/C(=O)OCC(CC)CCCC ROPXFXOUUANXRR-YPKPFQOOSA-N 0.000 description 1
- SAOKZLXYCUGLFA-UHFFFAOYSA-N bis(2-ethylhexyl) adipate Chemical compound CCCCC(CC)COC(=O)CCCCC(=O)OCC(CC)CCCC SAOKZLXYCUGLFA-UHFFFAOYSA-N 0.000 description 1
- 238000004061 bleaching Methods 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- IAQRGUVFOMOMEM-UHFFFAOYSA-N butene Natural products CC=CC IAQRGUVFOMOMEM-UHFFFAOYSA-N 0.000 description 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000010495 camellia oil Substances 0.000 description 1
- SHZIWNPUGXLXDT-UHFFFAOYSA-N caproic acid ethyl ester Natural products CCCCCC(=O)OCC SHZIWNPUGXLXDT-UHFFFAOYSA-N 0.000 description 1
- 239000011203 carbon fibre reinforced carbon Substances 0.000 description 1
- 150000001735 carboxylic acids Chemical class 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 229940106189 ceramide Drugs 0.000 description 1
- 150000001783 ceramides Chemical class 0.000 description 1
- WOWHHFRSBJGXCM-UHFFFAOYSA-M cetyltrimethylammonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+](C)(C)C WOWHHFRSBJGXCM-UHFFFAOYSA-M 0.000 description 1
- 150000003841 chloride salts Chemical class 0.000 description 1
- 235000018597 common camellia Nutrition 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
- 230000001186 cumulative effect Effects 0.000 description 1
- 125000006165 cyclic alkyl group Chemical group 0.000 description 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 description 1
- GHVNFZFCNZKVNT-UHFFFAOYSA-M decanoate Chemical compound CCCCCCCCCC([O-])=O GHVNFZFCNZKVNT-UHFFFAOYSA-M 0.000 description 1
- 125000005534 decanoate group Chemical class 0.000 description 1
- 125000002704 decyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- VKKVMDHHSINGTJ-UHFFFAOYSA-M di(docosyl)-dimethylazanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCCCCCC VKKVMDHHSINGTJ-UHFFFAOYSA-M 0.000 description 1
- XRWMGCFJVKDVMD-UHFFFAOYSA-M didodecyl(dimethyl)azanium;bromide Chemical compound [Br-].CCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCC XRWMGCFJVKDVMD-UHFFFAOYSA-M 0.000 description 1
- WLCFKPHMRNPAFZ-UHFFFAOYSA-M didodecyl(dimethyl)azanium;chloride Chemical compound [Cl-].CCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCC WLCFKPHMRNPAFZ-UHFFFAOYSA-M 0.000 description 1
- XCLAZFPLUVLIPV-UHFFFAOYSA-N didodecylazanium 2-sulfobutanedioate Chemical compound S(=O)(=O)(O)C(C(=O)[O-])CC(=O)[O-].C(CCCCCCCCCCC)[NH2+]CCCCCCCCCCCC.C(CCCCCCCCCCC)[NH2+]CCCCCCCCCCCC XCLAZFPLUVLIPV-UHFFFAOYSA-N 0.000 description 1
- HHVTVISHXVYKDX-UHFFFAOYSA-N dihexylazanium;2-sulfobutanedioate Chemical compound OS(=O)(=O)C(C([O-])=O)CC([O-])=O.CCCCCC[NH2+]CCCCCC.CCCCCC[NH2+]CCCCCC HHVTVISHXVYKDX-UHFFFAOYSA-N 0.000 description 1
- 229940031569 diisopropyl sebacate Drugs 0.000 description 1
- 229940008099 dimethicone Drugs 0.000 description 1
- UAKOZKUVZRMOFN-JDVCJPALSA-M dimethyl-bis[(z)-octadec-9-enyl]azanium;chloride Chemical compound [Cl-].CCCCCCCC\C=C/CCCCCCCC[N+](C)(C)CCCCCCCC\C=C/CCCCCCCC UAKOZKUVZRMOFN-JDVCJPALSA-M 0.000 description 1
- REZZEXDLIUJMMS-UHFFFAOYSA-M dimethyldioctadecylammonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC REZZEXDLIUJMMS-UHFFFAOYSA-M 0.000 description 1
- VJHINFRRDQUWOJ-UHFFFAOYSA-N dioctyl sebacate Chemical compound CCCCC(CC)COC(=O)CCCCCCCCC(=O)OCC(CC)CCCC VJHINFRRDQUWOJ-UHFFFAOYSA-N 0.000 description 1
- XFKBBSZEQRFVSL-UHFFFAOYSA-N dipropan-2-yl decanedioate Chemical compound CC(C)OC(=O)CCCCCCCCC(=O)OC(C)C XFKBBSZEQRFVSL-UHFFFAOYSA-N 0.000 description 1
- QNICMVJKCYAMIK-UHFFFAOYSA-L disodium octadecanoate Chemical compound [Na+].[Na+].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O QNICMVJKCYAMIK-UHFFFAOYSA-L 0.000 description 1
- SYNISXGCUQLMQF-UHFFFAOYSA-L disodium;2,2-didecyl-3-sulfobutanedioate Chemical compound [Na+].[Na+].CCCCCCCCCCC(C([O-])=O)(C(C([O-])=O)S(O)(=O)=O)CCCCCCCCCC SYNISXGCUQLMQF-UHFFFAOYSA-L 0.000 description 1
- VDCRQFNOANTCGX-UHFFFAOYSA-L disodium;2,2-diheptyl-3-sulfobutanedioate Chemical compound [Na+].[Na+].CCCCCCCC(C([O-])=O)(C(C([O-])=O)S(O)(=O)=O)CCCCCCC VDCRQFNOANTCGX-UHFFFAOYSA-L 0.000 description 1
- RZMWTGFSAMRLQH-UHFFFAOYSA-L disodium;2,2-dihexyl-3-sulfobutanedioate Chemical compound [Na+].[Na+].CCCCCCC(C([O-])=O)(C(C([O-])=O)S(O)(=O)=O)CCCCCC RZMWTGFSAMRLQH-UHFFFAOYSA-L 0.000 description 1
- 239000004664 distearyldimethylammonium chloride (DHTDMAC) Substances 0.000 description 1
- QIVLQXGSQSFTIF-UHFFFAOYSA-M docosyl(trimethyl)azanium;methyl sulfate Chemical compound COS([O-])(=O)=O.CCCCCCCCCCCCCCCCCCCCCC[N+](C)(C)C QIVLQXGSQSFTIF-UHFFFAOYSA-M 0.000 description 1
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- DDXLVDQZPFLQMZ-UHFFFAOYSA-M dodecyl(trimethyl)azanium;chloride Chemical compound [Cl-].CCCCCCCCCCCC[N+](C)(C)C DDXLVDQZPFLQMZ-UHFFFAOYSA-M 0.000 description 1
- 238000004043 dyeing Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- VUFOSBDICLTFMS-UHFFFAOYSA-M ethyl-hexadecyl-dimethylazanium;bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)CC VUFOSBDICLTFMS-UHFFFAOYSA-M 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- 150000002194 fatty esters Chemical class 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 150000002334 glycols Chemical class 0.000 description 1
- 230000003700 hair damage Effects 0.000 description 1
- 150000004820 halides Chemical class 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 125000003187 heptyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- UCZNZRYBJXGIAV-SSPAHAAFSA-N hexadecanoic acid;(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanal Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O.CCCCCCCCCCCCCCCC(O)=O UCZNZRYBJXGIAV-SSPAHAAFSA-N 0.000 description 1
- DWMMZQMXUWUJME-UHFFFAOYSA-N hexadecyl octanoate Chemical compound CCCCCCCCCCCCCCCCOC(=O)CCCCCCC DWMMZQMXUWUJME-UHFFFAOYSA-N 0.000 description 1
- OEWKLERKHURFTB-UHFFFAOYSA-M hexadecyl(trimethyl)azanium;methyl sulfate Chemical compound COS([O-])(=O)=O.CCCCCCCCCCCCCCCC[N+](C)(C)C OEWKLERKHURFTB-UHFFFAOYSA-M 0.000 description 1
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 description 1
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 229940100463 hexyl laurate Drugs 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 229940072106 hydroxystearate Drugs 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 1
- 229940078546 isoeicosane Drugs 0.000 description 1
- 229940093629 isopropyl isostearate Drugs 0.000 description 1
- 229940074928 isopropyl myristate Drugs 0.000 description 1
- 229940119170 jojoba wax Drugs 0.000 description 1
- 150000002576 ketones Chemical group 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 229940070765 laurate Drugs 0.000 description 1
- VMPHSYLJUKZBJJ-UHFFFAOYSA-N lauric acid triglyceride Natural products CCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCC)COC(=O)CCCCCCCCCCC VMPHSYLJUKZBJJ-UHFFFAOYSA-N 0.000 description 1
- 125000002463 lignoceryl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000000944 linseed oil Substances 0.000 description 1
- 235000021388 linseed oil Nutrition 0.000 description 1
- 125000002960 margaryl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- NQMRYBIKMRVZLB-UHFFFAOYSA-N methylamine hydrochloride Chemical compound [Cl-].[NH3+]C NQMRYBIKMRVZLB-UHFFFAOYSA-N 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
- 150000002772 monosaccharides Chemical class 0.000 description 1
- 125000001421 myristyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229940078555 myristyl propionate Drugs 0.000 description 1
- AFFLGGQVNFXPEV-UHFFFAOYSA-N n-decene Natural products CCCCCCCCC=C AFFLGGQVNFXPEV-UHFFFAOYSA-N 0.000 description 1
- 125000001196 nonadecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- GSGDTSDELPUTKU-UHFFFAOYSA-N nonoxybenzene Chemical compound CCCCCCCCCOC1=CC=CC=C1 GSGDTSDELPUTKU-UHFFFAOYSA-N 0.000 description 1
- 125000001400 nonyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000010466 nut oil Substances 0.000 description 1
- WWZKQHOCKIZLMA-UHFFFAOYSA-M octanoate Chemical compound CCCCCCCC([O-])=O WWZKQHOCKIZLMA-UHFFFAOYSA-M 0.000 description 1
- 229960002446 octanoic acid Drugs 0.000 description 1
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- CBFCDTFDPHXCNY-UHFFFAOYSA-N octyldodecane Natural products CCCCCCCCCCCCCCCCCCCC CBFCDTFDPHXCNY-UHFFFAOYSA-N 0.000 description 1
- 229940049964 oleate Drugs 0.000 description 1
- 150000002482 oligosaccharides Polymers 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 150000003961 organosilicon compounds Chemical class 0.000 description 1
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229940056211 paraffin Drugs 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 235000020232 peanut Nutrition 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 229940032066 peg-4 dilaurate Drugs 0.000 description 1
- 229940032051 peg-8 distearate Drugs 0.000 description 1
- 125000002958 pentadecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 description 1
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 description 1
- 239000013500 performance material Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229940113171 polysorbate 85 Drugs 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- NEOZOXKVMDBOSG-UHFFFAOYSA-N propan-2-yl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OC(C)C NEOZOXKVMDBOSG-UHFFFAOYSA-N 0.000 description 1
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical compound CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 235000005713 safflower oil Nutrition 0.000 description 1
- 239000003813 safflower oil Substances 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- CWBNBZNLLGLARL-UHFFFAOYSA-M sodium 4-oxo-4-(4-propyldecan-4-yloxy)-3-sulfobutanoate Chemical compound S(=O)(=O)(O)C(C(=O)OC(CCCCCC)(CCC)CCC)CC(=O)[O-].[Na+] CWBNBZNLLGLARL-UHFFFAOYSA-M 0.000 description 1
- APSBXTVYXVQYAB-UHFFFAOYSA-M sodium docusate Chemical compound [Na+].CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC APSBXTVYXVQYAB-UHFFFAOYSA-M 0.000 description 1
- 229910001415 sodium ion Inorganic materials 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- OQFRATAOPGTAOP-UHFFFAOYSA-M sodium;1,4-di(nonoxy)-1,4-dioxobutane-2-sulfonate Chemical compound [Na+].CCCCCCCCCOC(=O)CC(S([O-])(=O)=O)C(=O)OCCCCCCCCC OQFRATAOPGTAOP-UHFFFAOYSA-M 0.000 description 1
- UELAIMNOXLAYRW-UHFFFAOYSA-M sodium;1,4-dicyclohexyloxy-1,4-dioxobutane-2-sulfonate Chemical compound [Na+].C1CCCCC1OC(=O)C(S(=O)(=O)[O-])CC(=O)OC1CCCCC1 UELAIMNOXLAYRW-UHFFFAOYSA-M 0.000 description 1
- YWQIGRBJQMNGSN-UHFFFAOYSA-M sodium;1,4-dioxo-1,4-di(tridecoxy)butane-2-sulfonate Chemical compound [Na+].CCCCCCCCCCCCCOC(=O)CC(S([O-])(=O)=O)C(=O)OCCCCCCCCCCCCC YWQIGRBJQMNGSN-UHFFFAOYSA-M 0.000 description 1
- WGUGYSVJRCVEPZ-AWLASTDMSA-M sodium;bis[(z)-octadec-9-enyl] phosphate Chemical compound [Na+].CCCCCCCC\C=C/CCCCCCCCOP([O-])(=O)OCCCCCCCC\C=C/CCCCCCCC WGUGYSVJRCVEPZ-AWLASTDMSA-M 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000001589 sorbitan tristearate Substances 0.000 description 1
- 229960004129 sorbitan tristearate Drugs 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 150000003445 sucroses Chemical class 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- YRZGMTHQPGNLEK-UHFFFAOYSA-N tetradecyl propionate Chemical compound CCCCCCCCCCCCCCOC(=O)CC YRZGMTHQPGNLEK-UHFFFAOYSA-N 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 235000019149 tocopherols Nutrition 0.000 description 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 description 1
- 125000003944 tolyl group Chemical group 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 229940093609 tricaprylin Drugs 0.000 description 1
- 125000002469 tricosyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000002889 tridecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 150000005691 triesters Chemical class 0.000 description 1
- 229940118576 triisostearyl citrate Drugs 0.000 description 1
- HVLUSYMLLVVXGI-USGGBSEESA-M trimethyl-[(z)-octadec-9-enyl]azanium;chloride Chemical compound [Cl-].CCCCCCCC\C=C/CCCCCCCC[N+](C)(C)C HVLUSYMLLVVXGI-USGGBSEESA-M 0.000 description 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 description 1
- 229960001947 tripalmitin Drugs 0.000 description 1
- COXJMKGEQAWXNP-UHFFFAOYSA-N tris(14-methylpentadecyl) 2-hydroxypropane-1,2,3-tricarboxylate Chemical compound CC(C)CCCCCCCCCCCCCOC(=O)CC(O)(C(=O)OCCCCCCCCCCCCCC(C)C)CC(=O)OCCCCCCCCCCCCCC(C)C COXJMKGEQAWXNP-UHFFFAOYSA-N 0.000 description 1
- ICWQKCGSIHTZNI-UHFFFAOYSA-N tris(16-methylheptadecyl) 2-hydroxypropane-1,2,3-tricarboxylate Chemical compound CC(C)CCCCCCCCCCCCCCCOC(=O)CC(O)(C(=O)OCCCCCCCCCCCCCCCC(C)C)CC(=O)OCCCCCCCCCCCCCCCC(C)C ICWQKCGSIHTZNI-UHFFFAOYSA-N 0.000 description 1
- ZQTYRTSKQFQYPQ-UHFFFAOYSA-N trisiloxane Chemical compound [SiH3]O[SiH2]O[SiH3] ZQTYRTSKQFQYPQ-UHFFFAOYSA-N 0.000 description 1
- 125000002948 undecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 239000002888 zwitterionic surfactant Substances 0.000 description 1
- QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0291—Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/26—Optical properties
- A61K2800/262—Transparent; Translucent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
- A61K2800/31—Anhydrous
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Dispersion Chemistry (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to a transparent anhydrous composition for conditioning or caring for keratin materials, comprising: a) A continuous oily phase containing at least one oil; b) A surfactant combination of at least one nonionic surfactant and at least one ionic surfactant; and c) a dispersed phase comprising an organic solvent, wherein both the nonionic surfactant and the ionic surfactant are lipophilic. The invention also relates to a cosmetic process for conditioning or caring for keratin materials, comprising the application to said keratin materials of a composition according to the invention.
Description
Technical Field
The present invention relates to compositions for conditioning or caring for keratin materials, in particular human keratin materials such as the skin and hair. The invention also relates to a cosmetic method for conditioning or caring for keratin materials.
Background
Typically, external atmospheric factors such as light, weather and/or mechanical or chemical treatments such as brushing, combing, dyeing, bleaching, permanent waving (permanent) and/or straightening effects cause hair damage and friability.
There are many products available for conditioning hair that contain lipophilic active ingredients. For example, there are many hair oil products that contain lipophilic active ingredients.
WO 2000074644A1 discloses a composition comprising at least one organic phospholipid capable of forming bilayers in aqueous solution; at least one amphoteric surfactant; at least one nonionic surfactant present in an amount equal to or greater than the amount of phospholipids by weight; at least one suspending agent present in an amount effective to maintain a stable composition; and a lipophilic component.
EP0966955A1 discloses a cosmetic composition for treating keratin materials, comprising, in an aqueous medium, at least one polyorganosiloxane and an acrylic terpolymer. The terpolymer comprises: (1) Carboxylic acids (a) (20 to 70 wt%, preferably 25 to 55 wt%) having an α, β -monoethylenically unsaturated structure; (2) Monomers (B) other than (A) (20 to 80% by weight, preferably 30 to 65% by weight) having a non-surfactant monoethylenically unsaturated structure; and (3) a nonionic urethane monomer (C) (0.5 to 60% by weight, preferably 10 to 50% by weight) prepared by reacting a monohydroxy nonionic surfactant with a monoisocyanate, which has a monoethylenically unsaturated structure.
In order to meet the needs of various consumers, cosmetic manufacturers are eager to diversify the product types of hair oil products.
During the development of hair oil products, there are challenges to including ingredients that are soluble in organic solvents for conditioning hair.
In addition, it is highly desirable to use some products having a pleasing appearance, such as some products having a transparent appearance, to provide hair conditioning benefits.
It is also desirable that the product used to condition hair be stable over time.
This is also true for products used for caring for the skin.
Thus, there remains a need to develop compositions for conditioning hair or caring for skin that have a transparent appearance and are stable over time, and optionally contain an active ingredient soluble in an organic solvent for conditioning hair or caring for skin.
Summary of The Invention
It is therefore an object of the present invention to develop a composition for conditioning or caring for keratin materials, in particular human keratin materials such as skin and hair, which has a transparent appearance and is stable over time, and optionally comprises an active ingredient soluble in an organic solvent for conditioning the hair or caring for the skin.
Thus, according to a first aspect, the present invention provides a transparent anhydrous composition for conditioning or care of keratin materials, comprising:
a) A continuous oily phase containing at least one oil;
b) A surfactant combination of at least one nonionic surfactant and at least one ionic surfactant; and
C) A dispersed phase containing an organic solvent,
Wherein both the nonionic surfactant and the ionic surfactant are lipophilic.
According to a second aspect, the present invention provides a cosmetic process for conditioning or caring for keratin materials, comprising the application to keratin fibres of a composition as described above.
The inventors have found that reverse micelles are formed in the composition according to the invention, such that the composition has a transparent appearance and is thermodynamically stable over time, and that the composition is effective in conditioning or caring for keratin materials.
Other subjects and features, aspects and advantages of the present invention will become even more apparent upon reading the following detailed description and examples.
Drawings
The implementation of the invention will now be described, by way of example only, with reference to the accompanying drawings, in which:
Figure 1 shows the multimodal size distribution of the leave-on oil of example 1 of the present invention.
Figure 2 shows the multimodal size distribution of the leave-on oil of example 2 of the present invention.
Figure 3 shows the multimodal size distribution of the leave-on oil of example 3 of the present invention.
Figure 4 shows the multimodal size distribution of the leave-on oil of example 4 of the present invention.
Figure 5 shows the multimodal size distribution of the leave-on oil of example 5 of the present invention.
Figure 6 shows the multimodal size distribution of the leave-on oil of example 6 of the present invention.
Detailed Description
As used herein, unless otherwise indicated, the limits of the numerical ranges are included in the ranges, particularly in the expressions "between … and …" and "… to …".
The term "comprising" as used herein is to be interpreted as including all the specifically mentioned features as well as optional, additional, unspecified features
As used herein, the use of the term "comprising" also discloses embodiments in which no feature other than the specifically mentioned feature is present (i.e., "consisting of …").
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. To the extent that the definitions of terms in this specification conflict with the meanings commonly understood by those skilled in the art to which this invention pertains, the definitions set forth herein should apply.
Unless otherwise indicated, all numbers expressing quantities of ingredients and so forth used in the specification and claims are to be understood as being modified by the term "about". Thus, unless indicated to the contrary, the numerical values and parameters set forth herein are approximations that can vary depending upon the desired properties to be obtained.
For the purposes of this disclosure, the term "clear" is interchangeable with the term "transparent".
By "anhydrous" is meant that no water is deliberately added and the water content of the composition is less than 0.5 wt%, particularly less than 0.1 wt%, relative to the total weight of the composition. In particular, no water is present in the composition.
As used herein, the term "keratin materials" includes human keratin materials such as hair and skin.
As used herein, the expression "at least one" is equivalent to the expression "one or more".
As used herein, the term "reverse micelle" has the following definition: dissolving a surfactant in a nonpolar organic solvent; when their concentration exceeds the Critical Micelle Concentration (CMC), micelles form in the organic solvent, which is known as reverse micelles. In the reverse micelle, the nonpolar group of the surfactant is externally contacted with the nonpolar organic solvent, and the polar group is internally disposed to form the polar core. The polar core has the ability to dissolve polar materials. Reverse micelles are nanoscale aggregates that are transparent and thermodynamically stable W/O systems.
As used herein, the term "lipophilic" refers to a substance or material that can be dissolved or dispersed in an oil phase at 25 ℃ to obtain a macroscopically homogeneous phase.
According to a first aspect of the present invention, a transparent anhydrous composition for conditioning or care of keratin materials comprises:
a) A continuous oily phase containing at least one oil;
b) A surfactant combination comprising at least one nonionic surfactant and at least one ionic surfactant; and
C) A dispersed phase containing an organic solvent,
Wherein both the nonionic surfactant and the ionic surfactant are lipophilic.
Oil phase
According to a first aspect of the invention, the composition comprises a continuous oil phase comprising at least one oil.
Herein, "oil" refers to a fatty compound or substance that is in liquid or paste (non-solid) form at room temperature (25 ℃) and atmospheric pressure (760 mmHg).
As one or more oils, oils commonly used in cosmetic products may be used alone or in combination. These one or more oils may be volatile or non-volatile, preferably non-volatile.
The oil may be a non-polar oil, such as hydrocarbons, silicones, and the like; polar oils, such as esters, fatty alcohols, and ethers; or a combination thereof.
The oil may be of vegetable or animal origin and synthetic oil.
As examples of vegetable oils, mention may be made of, for example, linseed oil, camellia seed oil, macadamia nut oil, corn oil, mink oil, olive oil, avocado oil, camellia oil, castor oil, safflower oil, jojoba oil, sunflower oil, almond oil, rapeseed oil, sesame oil, soybean oil, peanut oil, and combinations thereof.
As examples of synthetic oils, alkane oils such as isododecane and isohexadecane, ester oils, ether oils and artificial triglycerides may be mentioned.
The ester oil is preferably a liquid ester of a saturated or unsaturated, linear or branched C 1-C26 aliphatic mono-or polyacid with a saturated or unsaturated, linear or branched C 1-C26 aliphatic mono-or polyol, the total number of carbon atoms of the ester being greater than or equal to 10.
Preferably, for esters of monohydric alcohols, at least one of the alcohol and acid from which the esters of the present invention are derived is branched.
Among the monoesters of monoacids and monoalcohols, mention may be made of ethyl palmitate, ethylhexyl palmitate, isopropyl palmitate, dioctyl carbonate, alkyl myristates such as isopropyl myristate or ethyl myristate, isocetyl stearate, 2-ethylhexyl isononanoate, isononyl isononanoate, isodecyl pivalate and isostearyl pivalate.
Esters of C 4-C22 di-or tricarboxylic acids with C 1-C22 alcohols and esters of mono-, di-or tricarboxylic acids with non-sugar C 4-C26 dihydric, trihydric, tetrahydroxy or penta-hydric alcohols may also be used.
Mention may be made in particular of: diethyl sebacate; isopropyl lauroyl sarcosinate; diisopropyl sebacate; bis (2-ethylhexyl) sebacate; diisopropyl adipate; di-n-propyl adipate; dioctyl adipate; bis (2-ethylhexyl) adipate; diisostearyl adipate; bis (2-ethylhexyl) maleate; triisopropanol citrate; triisocetyl citrate; triisostearyl citrate; glycerol trilactate; glyceryl trioctanoate; tri (octyldodecanol) citrate; triol citrate; neopentyl glycol diheptanoate; diethylene glycol diisononanoate.
As the ester oil, sugar esters and diesters of C 6-C30 fatty acids and preferably C 12-C22 fatty acids can be used. Recall that the term "sugar" refers to an oxygenated hydrocarbon-based compound containing several alcohol functions, with or without aldehyde or ketone functions, and which contains at least 4 carbon atoms. These sugars may be mono-, oligo-or polysaccharides.
Examples of suitable sugars that may be mentioned include sucrose (or sucrose), glucose, galactose, ribose, trehalose, maltose, fructose, mannose, arabinose, xylose and lactose, and derivatives thereof, in particular alkyl derivatives such as methyl derivatives, e.g. methyl glucose.
The sugar esters of fatty acids may in particular be selected from the esters or ester mixtures of the sugars described previously with linear or branched, saturated or unsaturated C 6-C30 fatty acids and preferably C 12-C22 fatty acids. If they are unsaturated, these compounds may have one to three conjugated or non-conjugated carbon-carbon double bonds.
The esters according to this variant may also be selected from monoesters, diesters, triesters, tetraesters and polyesters, and combinations thereof.
These esters may be, for example, oleates, laurates, palmitates, myristates, behenates, cocoates, stearates, linoleates, linolenates, caprates and arachidonates, or combinations thereof, such as, inter alia, oil palmitates, mixed esters of oil stearates and palmitostearates, and pentaerythritol tetraethyl hexanoate (PENTAERYTHRITYL TETRAETHYL hexaoate).
More particularly mono-and diesters are used, and in particular sucrose, glucose or methyl glucose mono-or dioleates, stearates, behenates, oil palmitates, linoleates, linolenates and oil stearates.
Examples which may be mentioned are the companies Amerchol under the nameDO, which is methyl glucose dioleate.
As examples of preferred ester oils, mention may be made, for example, of diisopropyl adipate, dioctyl adipate, 2-ethylhexyl caproate, ethyl laurate, cetyl caprylate, octyldodecyl caprylate, isodecyl pivalate, myristyl propionate, 2-ethylhexyl 2-ethylhexanoate, 2-ethylhexyl caprylate, 2-ethylhexyl capryl/caprate, methyl palmitate, ethyl palmitate, isopropyl palmitate, dioctyl carbonate, isopropyl lauroyl sarcosinate, isononyl isononanoate, ethylhexyl palmitate, isohexyl laurate, hexyl laurate, isocetyl stearate, isopropyl isostearate, isopropyl myristate, isodecyl oleate, tri (2-ethylhexanoate), pentaerythritol tetra (2-ethylhexanoate), 2-ethylhexyl succinate, diethyl sebacate, and combinations thereof.
As examples of artificial triglycerides, mention may be made of, for example, caprylic/capric triglyceride, trimyristate glyceride, tripalmitin, trilinein glyceride, trilaurin glyceride, tricapran glyceride, tricaprylin glyceride, and tris (capric/caprylic/linolenic) glyceride.
The ether hydrocarbon-based oil, also known as an ether oil, may be volatile or nonvolatile, and is preferably nonvolatile.
The ether hydrocarbon-based oil is an oil of formula R 1OR2, wherein R 1 and R 2 independently represent a linear, branched or cyclic C 4-C24 alkyl group, preferably a C 6-C18 alkyl group, and preferably a C 8-C12 alkyl group. It may be preferred that R 1 and R 2 are the same.
Straight-chain alkyl groups which may be mentioned include butyl, pentyl, hexyl, heptyl, octyl, nonyl, decyl, undecyl, dodecyl, tridecyl, tetradecyl, pentadecyl, hexadecyl, heptadecyl, octadecyl, nonadecyl, eicosyl, behenyl, docosyl, tricosyl and tetracosyl.
Branched alkyl radicals which may be mentioned include 1-methylpropyl, 2-methylpropyl, tert-butyl, 1-dimethylpropyl, 3-methylhexyl, 5-methylhexyl, ethylhexyl, 2-ethylhexyl, 5-methyloctyl, 1-ethylhexyl, 1-butylpentyl, 2-butyloctyl, isotridecyl, 2-pentylnonyl, 2-hexyldecyl, isostearyl, 2-heptylundecyl, 2-octyldodecyl, 1, 3-dimethylbutyl, l- (l-methylethyl) -2-methylpropyl, 1, 3-tetramethylbutyl, 3, 5-trimethylhexyl, l- (2-methylpropyl) -3-methylbutyl, 3, 7-dimethyloctyl and 2- (l), 3, 3-trimethylbutyl) -5, 7-trimethyloctyl.
Cyclic alkyl groups which may be mentioned include cyclohexyl, 3-methylcyclohexyl and 3, 5-trimethylcyclohexyl.
Advantageously, the ether oil is selected from the group consisting of dioctyl ether (DICAPRYLYL ETHER), didecyl ether, dilauryl ether, diisostearyl ether, dioctyl ether (dioctoyl ether), nonylphenyl ether, dodecyldimethylbutyl ether, cetyl dimethylbutyl ether, cetyl isobutyl ether, and combinations thereof.
Preferably, it is selected from the group consisting of dioctyl ether (DICAPRYLYL ETHER), didecyl ether, dilauryl ether, diisostearyl ether, dioctyl ether (dioctyl ether), and combinations thereof. Dioctyl ether (DICAPRYLYL ETHER) is most particularly suitable for use.
As examples of silicone oils, mention may be made, for example, of linear organopolysiloxanes such as polydimethylsiloxane, methylphenyl polysiloxane, methyl hydrogen polysiloxane, and the like; cyclic organopolysiloxanes such as cyclohexasiloxane, octamethyl cyclotetrasiloxane, decamethyl cyclopentasiloxane, dodecamethyl cyclohexasiloxane, and the like; and combinations thereof.
Preferably, the silicone oil is selected from liquid polydialkylsiloxanes, in particular liquid Polydimethylsiloxanes (PDMS) and liquid polyorganosiloxanes comprising at least one aryl group.
These silicone oils may also be organically modified. The organomodified silicones that can be used according to the invention are silicone oils as defined above and contain one or more organofunctional groups in their structure linked via hydrocarbon-based groups.
Organopolysiloxane is defined in more detail in CHEMISTRY AND Technology of Silicones (1968), ACADEMIC PRESS of Walter Noll. They may be volatile or non-volatile.
When they are volatile, the silicones are more particularly selected from those having a boiling point of 60 ℃ to 260 ℃, and even more particularly selected from:
(i) Cyclic polydialkylsiloxanes comprising 3 to 7 and preferably 4 to 5 silicon atoms. These are for example given the name Volatile by Union Carbide 7207 Or by Rhodia under the name/>70045V2 octamethyl cyclotetrasiloxane sold under the name Volatile/>, by Union Carbide7158. Under the name Rhodia70045V5, dodecamethyl cyclopentasiloxane sold under the name Silsoft 1217 by Momentive Performance Materials, and combinations thereof. Mention may also be made of cyclic copolymers (of the type for example dimethylsiloxane/methylalkylsiloxane), such as Silicone/>, sold by the company Union CarbideFZ 3109 has the formula:
mention may also be made of mixtures of cyclic polydialkylsiloxanes with organosilicon compounds, for example mixtures of octamethylcyclotetrasiloxane and tetrakis (trimethylsilyl) pentaerythritol (tetratrimethylsilylpentaerythritol) (50/50), and mixtures of octamethylcyclotetrasiloxane and oxygen-1, 1' -bis (2, 2', 3' -hexatrimethylsilyloxy) neopentane;
(ii) Linear volatile polydialkylsiloxanes containing 2 to 9 silicon atoms and having a viscosity of less than or equal to 5 x 10 -6m2/s at 25 ℃. One example is decamethyltetrasiloxane sold under the name SH 200, particularly by the company Toray Silicone. Silicones belonging to this class are also described in the articles published in Cosmetics and Toiletries, volume 91, month 1 of 76, pages 27-32, todd & Byers, volatile Silicone Fluidsfor Cosmetics. The viscosity of the silicone was measured at 25 ℃ according to ASTM standard 445 appendix C.
Nonvolatile polydialkylsiloxanes may also be used. These non-volatile silicones are more particularly chosen from polydialkylsiloxanes, among which mention may be made mainly of polydimethylsiloxanes containing trimethylsilyl end groups.
Among these polydialkylsiloxanes, mention may be made, by way of non-limiting example, of the following commercial products:
-series 47 and 70047 sold by Rhodia Oil or/>Oils, such as oil 70047V 500000;
Sold by the company Rhodia A series of oils;
-a series 200 oil from Dow Corning, company, for example DC200 with a viscosity of 60000mm 2/s;
-from GENERAL ELECTRIC Oil and certain oils from the SF series of GENERAL ELECTRIC (SF 96, SF 18).
Mention may also be made of polydimethylsiloxanes containing dimethylsilanol end groups known under the name dimethiconol (CTFA), for example the 48 series of oils from the company Rhodia.
Among the aryl-containing silicones are polydiarylsiloxanes, in particular polydiphenylsiloxanes and polyalkylarylsiloxanes. Examples that may be mentioned include products sold under the following names:
-70641 series from Rhodia An oil;
-from Rhodia 70633 And 763 series of oils;
-oil Dow Corning 556Cosmetic Grade Fluid from Dow Corning;
Silicones from the Bayer PK series, such as product PK20;
Some oils from the SF series of GENERAL ELECTRIC, such as SF 1023, SF 1154, SF 1250 and SF 1265.
The organically modified liquid silicone may contain, in particular, polyoxyethylene groups and/or polyoxypropylene groups. Thus, mention may be made of silicone KF-6017 by Shin-Etsu and oils from the company Union CarbideL722 and L77.
The hydrocarbon oil may be selected from:
-a linear or branched, optionally cyclic, C 6-C16 lower alkane. Examples which may be mentioned include hexane, undecane, dodecane, tridecane and isoparaffins, such as isohexadecane, isododecane and isodecane; and
Linear or branched hydrocarbons containing more than 16 carbon atoms, such as liquid paraffin, liquid petrolatum (petrolatum), polydecene and hydrogenated polyisobutene such asAnd squalane.
As preferable examples of the hydrocarbon oil, for example, straight-chain or branched hydrocarbons such as isohexadecane, isododecane, squalane, mineral oil (e.g., liquid paraffin), paraffin, vaseline or petrolatum (petrolatum), naphthalene, and the like; hydrogenated polyisobutene, isoeicosane and decene/butene copolymers; and combinations thereof.
Preferably, the oil is selected from branched alkane oils containing 8 to 20 carbon atoms and more preferably 10 to 16 carbon atoms such as isododecane, triglycerides such as caprylic/capric triglyceride, ether hydrocarbon based oils having a C 8-C12 alkyl group such as dioctyl ether, polydimethylsiloxanes optionally containing dimethylsilanol end groups such as polydimethylsiloxane (dimethicone), dimethiconol, and combinations thereof.
More preferably, the oil is selected from the group consisting of isododecane, dioctyl ether, caprylic/capric triglyceride, polydimethylsiloxane, dimethiconol, and combinations thereof.
Advantageously, the oil is present in an amount ranging from 80% to 98.5% by weight, preferably from 85% to 97.5% by weight, more preferably from 88% to 94% by weight, relative to the total weight of the composition.
Surface active agent
According to a first aspect of the present invention, a composition comprises a surfactant combination comprising at least one nonionic surfactant and at least one ionic surfactant.
Preferably, the composition according to the invention comprises at least one nonionic surfactant and at least one cationic surfactant, or at least one nonionic surfactant and at least one anionic surfactant.
In some embodiments, the compositions according to the present invention comprise at least one nonionic surfactant and at least one cationic surfactant, or at least one nonionic surfactant and at least one anionic surfactant as the only surfactants.
By means of a specific surfactant combination, the organic solvent contained in the dispersed aqueous phase is relatively high and sufficient to carry an effective amount of the active ingredient soluble in the organic solvent.
In fact, the surfactant combinations of the present invention achieve synergistic effects. In this context, the term "synergistic effect" means that the amount of organic solvent contained in the dispersed aqueous phase from the surfactant action of the present invention is higher than the sum of the amounts of organic solvent contained in the dispersed aqueous phase from each individual surfactant action contained in the surfactant combination.
Advantageously, the surfactant combination is present in an amount of from about 0.1wt% to about 20 wt%, preferably from about 0.5 wt% to about 10 wt%, or from about 1wt% to about 5 wt%, relative to the total weight of the composition.
Ionic surfactants
In this context, the term "ionic surfactant" refers to a surfactant having at least one anion or cation in the molecule, and non-limiting examples that may be mentioned are anionic surfactants, cationic surfactants, amphoteric surfactants and zwitterionic surfactants.
The ionic surfactant according to the present invention is preferably selected from anionic surfactants, cationic surfactants, and combinations thereof. In most embodiments, the anionic surfactant and the cationic surfactant are not included in the compositions of the present invention at the same time, and even if they are included at the same time, the amount of one of them is significantly lower or higher than the other to avoid undesirable interactions.
Furthermore, the ionic surfactants according to the invention are lipophilic.
As anionic surfactants there may be mentioned anionic surfactants having at least one C 6-C22 alkyl chain, for example one or two C 6-C22 alkyl chains, and preferably two C 6-C22 alkyl chains. For example, the anionic surfactant is selected from the group consisting of alkyl sulfosuccinates, especially dialkyl sulfosuccinates, wherein the alkyl group has from 6 to 22 carbon atoms, preferably from 6 to 12 carbon atoms. Different or identical alkyl groups may be present in one dialkyl sulfosuccinate salt molecule, with identical alkyl groups being preferred. Alkyl groups may be linear, branched or cyclic, saturated or unsaturated, and substituted or unsubstituted.
As counter ion for the sulfonic acid group, alkali metal cations, alkaline earth metal cations or ammonium ions, in particular sodium ions, can be used. Preferably, the dialkyl sulfosuccinate salt is selected from the group consisting of dialkyl sulfosuccinate salts wherein each alkyl group has 6 to 22 carbon atoms and the counter ion of the sulfonic acid group is selected from the group consisting of alkali metal cations and ammonium ions.
Non-limiting examples of alkyl sulfosuccinates include sodium diethylhexyl sulfosuccinate, sodium dinonyl sulfosuccinate, sodium diisononyl sulfosuccinate, sodium dioctyl sulfosuccinate (dioctyl sodium sulfosuccinate), sodium diheptyl sulfosuccinate, sodium dihexyl sulfosuccinate, sodium dioctyl sulfosuccinate (dicapryl sodium sulfosuccinate), sodium didecyl sulfosuccinate, sodium di (undecyl) sulfosuccinate (diundecyl sodium sulfosuccinate), sodium dilauryl sulfosuccinate, sodium dicotyl sulfosuccinate (dicocoyl sodium sulfosuccinate), sodium ditridecyl sulfosuccinate (DITRIDECYL SODIUM SULFOSUCCINATE), sodium dipropylheptyl sulfosuccinate, sodium dicyclohexyl sulfosuccinate, ammonium diethylhexyl sulfosuccinate, ammonium dinonyl sulfosuccinate, ammonium diisononyl sulfosuccinate dioctyl ammonium sulfosuccinate, diheptyl ammonium sulfosuccinate, dihexyl ammonium sulfosuccinate, di Xin Zhian (ammonium dicapryl sulfosuccinate) of sulfosuccinate, didecyl ammonium sulfosuccinate, di undecyl ammonium sulfosuccinate, dilauryl ammonium sulfosuccinate, ditolyl ammonium sulfosuccinate, ditridecyl ammonium sulfosuccinate, dipropyl heptyl ammonium sulfosuccinate, dicyclohexyl ammonium sulfosuccinate, diethylhexyl potassium sulfosuccinate, dinonyl potassium sulfosuccinate, diisononyl potassium sulfosuccinate, dioctyl potassium sulfosuccinate (dioctyl potassium sulfosuccinate), diheptyl potassium sulfosuccinate, dihexyl potassium sulfosuccinate, dioctyl potassium sulfosuccinate (dicapryl potassium sulfosuccinate), didecyl potassium sulfosuccinate, potassium di (undecyl) sulfosuccinate, dilauryl sulfosuccinate, potassium di cocoyl sulfosuccinate, ditridecyl sulfosuccinate, dipropylheptyl sulfosuccinate and dicyclohexyl sulfosuccinate.
Other non-limiting examples of anionic surfactants include 1, 3-dioctyl glycerol ether hydroxypropyl sulfonate, 1, 3-didecyl glycerol ether hydroxypropyl sulfonate, 1, 3-didodecyl glycerol ether hydroxypropyl sulfonate, sodium distearate, sodium dioleyl phosphate, 1, 2-dioleoyl-sn-glycero-3-phosphate (sodium salt), sodium dilauryl glutamine lysine and sodium ethylenebis (N-lauroyl-aspartate), and the like.
Preferably, the anionic surfactant is selected from the group consisting of dialkyl sulfosuccinates, wherein each alkyl group has 6 to 22 carbon atoms, preferably 6 to 12 carbon atoms, and both alkyl groups are identical. In some embodiments, the anionic surfactant is sodium diethylhexyl sulfosuccinate.
As cationic surfactants, mention may be made of fatty quaternary ammonium compounds, and preferably fatty quaternary ammonium compounds having at least one C 6-C22 alkyl chain, for example one, two or three C 6-C22 alkyl chains, of which two C 6-C22 alkyl chains are preferred. Different or identical alkyl groups may be present in one molecule of the fatty quaternary ammonium compound having two or three C 6-C22 alkyl chains, with identical alkyl groups being preferred. The alkyl group may be linear, branched or cyclic, saturated or unsaturated, and substituted or unsubstituted, and is preferably linear and saturated. In some embodiments, the cationic surfactant is selected from the group consisting of alkyl trimethylammonium, dialkyl dimethylammonium, trialkyl methylammonium, and combinations thereof, wherein each alkyl group contains from 6 to 22 carbon atoms, and preferably from 12 to 22 carbon atoms.
The anions of the quaternary ammonium compounds can be common ions, for example, halogen ions include chloride and bromide, ethyl sulfate, methyl sulfate, acetate, lactate, nitrate, phosphate, tosylate, and combinations thereof. Preferably, the anion of the quaternary ammonium compound is selected from chloride, methyl sulfate and bromide, and especially chloride.
Non-limiting examples of fatty quaternary ammonium compounds include cetyltrimethylammonium chloride, stearyl trimethylammonium chloride (stearimonium chloride), behenyl trimethylammonium chloride, cetyltrimethylammonium methyl sulfate, behenyl trimethylammonium methyl sulfate, peanut trimethylammonium chloride (arachidtrimonium chloride), distearyl dimethylammonium chloride, dicetyl dimethylammonium chloride, tricetyl trimethylammonium chloride, cetyltrimethylammonium bromide, lauryl trimethylammonium chloride, myristyl trimethylammonium bromide, oleyl trimethylammonium chloride, dimethyl dilauryl ammonium bromide, dibehenyl dimethylammonium chloride, dioleyl dimethylammonium chloride, tristearyl methylammonium chloride, dilauryl dimethylammonium chloride, cocoyl trimethylammonium chloride, cetyl ethyldimethylammonium bromide (cethethyldimonium bromide), stearyl octanediammonium methyl sulfate, 1, 2-dioleoyl-3-trimethylammonium-propane (chloride salt), and combinations thereof.
Preferably, the cationic surfactant is selected from dialkyldimethylammonium halides, wherein each alkyl group contains 6 to 22 carbon atoms, and preferably 12 to 22 carbon atoms, and both alkyl groups are identical. In some embodiments, the cationic surfactant is dicetyl dimethyl ammonium chloride.
Advantageously, the ionic surfactant is present in an amount of from 0.01% to 5% by weight, preferably from 0.1% to 2% by weight, more preferably from 0.1% to 1% by weight, relative to the total weight of the composition.
Nonionic surfactant
The nonionic surfactant according to the invention is lipophilic.
As the nonionic surfactant, nonionic surfactants having at least one C 6-C22 alkyl chain, for example, one, two or three C 6-C22 alkyl chains, may be mentioned, and preferably the nonionic surfactants further have an HLB value of about 0 to about 10.
As examples, mention may be made of esters of polyols with fatty acids having saturated or unsaturated chains containing, for example, 6-22 carbon atoms, preferably 12 to 22 carbon atoms, and alkoxylated derivatives thereof, preferably having an alkylene oxide number of 10 to 200, and more preferably 10 to 100, for example one or more glycerides of C 6-C22, preferably C 12-C22 fatty acids and alkoxylated derivatives thereof, preferably having an alkylene oxide number of 10 to 200, and more preferably 10 to 100; polyethylene glycol esters of one or more C 6-C22, preferably C 12-C22 fatty acids and alkoxylated derivatives thereof, preferably having an alkylene oxide number of 10 to 200, and more preferably 10 to 100; one or more sorbitol esters of C 6-C22, preferably C 12-C22 fatty acids and alkoxylated derivatives thereof, preferably having an alkylene oxide number of 10 to 200, and more preferably 10 to 100; one or more sugar (sucrose, glucose, alkyl sugar) esters of C 6-C22, preferably C 12-C22 fatty acids and alkoxylated derivatives thereof, preferably having an alkylene oxide number of from 10 to 200, and more preferably from 10 to 100; and combinations thereof.
Examples of ethoxylated fatty esters that may be mentioned include adducts of ethylene oxide with esters of lauric, palmitic, stearic or behenic acid, and combinations thereof, especially those containing 9 to 100 ethylene oxide groups, such as ethylene glycol dilaurate, ethylene glycol distearate, PEG-3 distearate, PEG-8 distearate, PEG-12 distearate, PEG-100 distearate, PEG-150 distearate, PEG-2 dilaurate, PEG-4 dilaurate, PEG-8 dilaurate, ethylene glycol dioleate, PEG-3 dioleate, PEG-4 dioleate, and the like.
Examples of the glycerol ester of fatty acid include glycerol stearate (di-and/or tristearin), for example, 1, 3-distearin, glycerol dioleate, glycerol dilaurate, 1, 3-dipalmitin, and combinations thereof.
As polyglycerol esters of fatty acids, the polyglycerol moiety may be derived from 2 to 10 glycerols, preferably 2 to 8 glycerols, or 2 to 6 glycerols, and/or the fatty acid may be a C 6-C22 fatty acid, and preferably a C 12-C22 fatty acid.
Polyglycerol esters of fatty acids may be selected from mono-, di-, tri-or sesqui-esters of linear or branched saturated or unsaturated fatty acids, such as lauric acid, oleic acid, stearic acid, isostearic acid, capric acid, caprylic acid, palmitic acid and myristic acid.
The polyglycerol esters of fatty acids may be selected from polyglycerol mono-, di-, tri-or sesquioctanoates comprising 2 to 10 glycerol units, polyglycerol mono-, di-, tri-or sesquidecanoates comprising 2 to 10 glycerol units, polyglycerol mono-, di-, tri-or sesquilaurates comprising 2 to 10 glycerol units, polyglycerol mono-, di-, tri-or sesquimyristates comprising 2 to 10 glycerol units, polyglycerol mono-, di-, tri-or sesquipalmitates comprising 2 to 10 glycerol units, polyglycerol mono-, di-, tri-or sesquistearates comprising 2 to 10 glycerol units, polyglycerol mono-, di-, tri-or sesquioleates comprising 2 to 10 glycerol units, and combinations thereof, wherein fatty acids comprising 2 to 6 glycerol units and/or polyglycerol esters derived from C 12-C22 fatty acids are preferred.
Sorbitol esters of C 6-C22 fatty acids and their alkoxylated derivatives may be selected from sorbitan tristearate, sorbitan trioleate and esters of fatty acids such as span 65, span 85 with alkoxylated sorbitol anhydrides containing for example 20 to 100 EO, for example polyethylene sorbitan trioleate (polysorbate 85) or compounds sold under the trade names Tween 20 or Tween 60 by Croda.
As esters of fatty acids and glucose or alkyl glucose, mention may be made in particular of glucose palmitate, alkyl glucose sesquistearate, such as methyl glucose sesquistearate, alkyl glucose palmitate, such as methyl glucose or ethyl glucose palmitate, methyl glucoside fatty esters, and more particularly diesters of methyl glucoside and oleic acid (methyl glucose dioleate), mixed esters of methyl glucoside and the mixture oleic acid/hydroxystearic acid (methyl glucose dioleate/hydroxystearate), esters of methyl glucoside and isostearic acid (methyl glucose isostearate), esters of methyl glucoside and lauric acid (methyl glucose laurate), mixtures of mono-and diesters of methyl glucoside and isostearic acid (methyl glucose sesquistearate), mixtures of mono-and diesters of methyl glucoside and stearic acid (methyl glucose sesquistearate), and in particular the products sold under the name Glucate SS by Lubrizol, and mixtures thereof.
As ethoxylated ethers of fatty acids and glucose or alkyl glucose, there may be mentioned, for example, ethoxylated ethers of fatty acids and methyl glucose, and in particular polyethylene glycol ethers of methyl glucose with about 20 moles of ethylene oxide (PEG-20 methyl glucose distearate) of diesters of methyl glucose with stearic acid, such as the product sold under the name GLUCAM E-20DISTEARATE by Lubrizol, polyethylene glycol ethers of mixtures of mono-and diesters of methyl glucose with stearic acid with about 20 moles of ethylene oxide (PEG-20 methyl glucose sesquistearate), and in particular the product sold under the name GLUCAMATE SSE-20 by Lubrizol, and combinations thereof.
Examples of sucrose esters include sucrose dilaurate, sucrose trilaurate, sucrose dioleate, sucrose trioleate and sucrose tristearate.
Preferably, the nonionic surfactant is selected from polyglycerol esters of fatty acids; in particular polyglycerol monooleate, polyglycerol dioleate or polyglycerol trioleate containing from 2 to 6 glycerol units, polyglycerol monoisostearate, polyglycerol diisostearate or polyglycerol triisostearate containing from 2 to 6 glycerol units, and combinations thereof.
More preferably, the nonionic surfactant is selected from the group consisting of polyglycerol-6 dioleate, polyglycerol-2 oleate, polyglycerol-2 triisostearate, and combinations thereof.
Advantageously, the nonionic surfactant is present in an amount of from 0.01% to 20% by weight, preferably from 0.1% to 10% by weight, more preferably from 0.1% to 5% by weight, most preferably from 0.5% to 4% by weight, relative to the total weight of the composition.
Disperse phase
According to a first aspect of the invention, the composition comprises a dispersed phase comprising an organic solvent.
The dispersed phase of the composition according to the invention comprises an organic solvent selected from the group consisting of organic alcohols such as ethanol, octyldodecanol, butylene glycol, dipropylene glycol, propylene glycol (propylene glycol) and propylene glycol (propylene glycol).
The organic solvent acts as the core of the reverse micelle to encapsulate the active ingredient that is soluble in the organic solvent.
Advantageously, the organic solvent is present in an amount ranging from 0.1% to 10% by weight, preferably from 0.2% to 5% by weight, more preferably from 0.3% to 2% by weight, relative to the total weight of the composition.
Cosmetic active ingredient
Preferably, the composition comprises a cosmetic active ingredient having a solubility in an organic solvent of not less than 10 g.
The cosmetic active ingredient may be present inside the core of the micelle containing the organic solvent or at the solvent-oil interface.
As examples of cosmetic active ingredients, mention may be made of UV filters, such as avobenzone, homosalate, ethylhexyl salicylate, octocrylene; ceramides, such as 2-oleamido-1, 3-octadecanediol, N-stearoyl-phytosphingosine, hydroxypalmitoyl dihydrosphingosine; tocopherols and salicylic acid.
If present, the cosmetic active ingredient is advantageously present in an amount of from 0.001% to 5% by weight, preferably from 0.01% to 2% by weight, and more preferably from 0.1% to 1% by weight, relative to the total weight of the composition.
Adjuvant
The composition according to the invention may also comprise effective amounts of other ingredients, such as fragrances, preservatives and the like.
The amount of additional adjuvant can be selected by one skilled in the art so as not to negatively affect the end use of the composition according to the invention.
According to a preferred embodiment, the present invention provides a transparent anhydrous composition for conditioning or care of keratin materials, comprising, with respect to the total weight of the composition:
a) 88 to 94 weight percent of at least one oil selected from the group consisting of isododecane, dioctyl ether, caprylic/capric triglyceride, polydimethylsiloxane, dimethiconol, and combinations thereof;
b) 0.1 to 1.0 wt% of at least one cationic surfactant selected from dialkyl dimethyl ammonium halides, and 0.1 to 1.0 wt% of at least one nonionic surfactant selected from polyglycerol monooleate, polyglycerol dioleate, or polyglycerol trioleate containing 2 to 6 glycerol units, polyglycerol monoisostearate, polyglycerol diisostearate, or polyglycerol triisostearate containing 2 to 6 glycerol units, and combinations thereof;
c) 0.3 to 2 weight percent of at least one organic solvent selected from the group consisting of ethanol, octyldodecanol, butylene glycol, dipropylene glycol, propylene glycol (propanediol), and propylene glycol (propylene glycol), and combinations thereof; and
D) 0.1 to 1% by weight of at least one cosmetic active ingredient selected from avobenzone, homosalate, ethylhexyl salicylate, octocrylene, 2-oleoyl-1, 3-octadecanediol, N-stearoyl-phytosphingosine, hydroxypalmitoyl dihydrosphingosine, salicylic acid, and combinations thereof,
Wherein both the nonionic surfactant and the cationic surfactant are lipophilic.
Preparation and use
The composition according to the invention can be prepared by mixing the components a) to c) as essential components, together with one or more additional components as described above.
There is no limitation on the method and means of mixing the above basic and optional ingredients. Any conventional method and means may be used to mix the above basic and optional ingredients to prepare the compositions according to the present invention.
The process for the preparation of the composition according to the invention does not require an energy consuming step.
Reverse micelles are formed in the composition according to the invention.
The presence of reverse micelles can be confirmed by measuring the size of the reverse micelles by Dynamic Light Scattering (DLS).
The compositions according to the invention are useful as conditioning leave-on or rinse-off products for hair or skin care.
The composition can potentially deliver the functionality of an active ingredient that is soluble in an organic solvent to consumer perceivable benefits.
According to a second aspect of the present invention, a cosmetic process for conditioning or caring for keratin materials, comprising the application to keratin materials of a composition as described above.
The following examples are given by way of illustration of the invention and should not be construed as limiting the scope.
Examples
The main raw materials used, trade names and suppliers thereof are listed in table 1.
TABLE 1
/>
Inventive examples 1-3 and comparative examples 1-3
Leave-on oils according to inventive formulations (IE.) 1-3 and comparative formulations (ce.) 1-3 were prepared with the ingredients listed in table 2 (unless otherwise indicated, the amounts are expressed as weight percent of active material relative to the total weight of each leave-on oil):
TABLE 2
/>
The preparation process comprises the following steps:
Each leave-in oil was prepared as follows:
1) Mixing polydimethylsiloxane, dimethiconol, triglyceride, isododecane, trimethylsiloxysilicate, dioctyl ether and perfume under stirring to obtain hair base material;
2) Adding a surfactant to the hair base by thorough stirring;
3) Adding the polyol to the hair oil containing the surfactant by stirring thoroughly to obtain a leave-on oil.
Evaluation:
The stability of each of the obtained leave-on oils was evaluated by keeping the leave-on oil at 4 ℃, room temperature (20 ℃) or 45 ℃ for 2 months and visually checking whether the leave-on oil is transparent. The wash-free oil tested will be evaluated as stable if it is transparent at all 4 ℃, room temperature (20 ℃) and 45 ℃ for 2 months, otherwise it will be evaluated as unstable.
The appearance of each of the obtained leave-on oils was visually observed.
The results are summarized in table 3.
TABLE 3 Table 3
/>
Inventive examples 4-5 and comparative example 4
Leave-on oils according to inventive formulations (IE.) 4-5 and comparative formulation (ce.) 4 were prepared with the ingredients listed in table 4 (unless otherwise indicated, the amounts are expressed as weight percent of active material relative to the total weight of each leave-on oil):
TABLE 4 Table 4
The preparation process comprises the following steps:
Each leave-in oil was prepared as follows:
1) Mixing polydimethylsiloxane, isododecane, trisiloxane and perfume by stirring thoroughly to obtain hair oil base material;
2) Mixing 2-oleoyl amido-1, 3-octadecanediol and octyldodecanol by thorough stirring and heating if necessary to obtain active/solvent preparation phase;
3) Adding a surfactant to the hair base by thorough stirring;
4) Adding the active/solvent preparation phase to a hair oil containing a surfactant by stirring thoroughly to obtain a leave-on oil.
Evaluation:
The stability of each of the obtained leave-on oils was evaluated by keeping the leave-on oil at 4 ℃, room temperature (20 ℃) or 45 ℃ for 2 months and visually checking whether the leave-on oil is transparent. The wash-free oil tested will be evaluated as stable if it is transparent at all 4 ℃, room temperature (20 ℃) and 45 ℃ for 2 months, otherwise it will be evaluated as unstable.
The appearance of each of the obtained leave-on oils was visually observed.
The results are summarized in table 5.
TABLE 5
Inventive example 6 and comparative example 5
Leave-on oils according to inventive formulation (IE.) 6 and comparative formulation (ce.) 5 were prepared with the ingredients listed in table 6 (unless otherwise indicated, the amounts are expressed as weight percent of active material relative to the total weight of each leave-on oil):
TABLE 6
The preparation process comprises the following steps:
Each leave-in oil was prepared as follows:
1) Mixing polydimethylsiloxane, dimethiconol, triglyceride, isododecane, trimethylsiloxysilicate, dioctyl ether and perfume under stirring to obtain hair base material;
2) Mixing 2-oleoyl amido-1, 3-octadecanediol and octyldodecanol by thorough stirring and heating if necessary to obtain active/solvent preparation phase;
3) Adding a surfactant to the hair base by thorough stirring;
4) Adding the active/solvent preparation phase to a hair oil containing a surfactant by stirring thoroughly to obtain a leave-on oil.
Evaluation:
The stability of each of the obtained leave-on oils was evaluated by keeping the leave-on oil at 4 ℃, room temperature (20 ℃) or 45 ℃ for 2 months and visually checking whether the leave-on oil is transparent. The wash-free oil tested will be evaluated as stable if it is transparent at all 4 ℃, room temperature (20 ℃) and 45 ℃ for 2 months, otherwise it will be evaluated as unstable.
The appearance of each of the obtained leave-on oils was visually observed.
The results are summarized in table 7.
TABLE 7
Measurement of size of reverse micelles
The size of the reverse micelles was characterized using a Brookhaven Dynamic Light Scattering (DLS) device. The main experimental parameters set for the DLS experiments are listed in table 8.
TABLE 8
The effective diameter and polydispersity index were obtained from at least three measurements. The average effective diameters and average polydispersity indices are summarized in table 9.
Polydispersity index (PDI) is a dimensionless measure of the width of the size distribution calculated from the cumulative amount analysis. This value should be 0 to 1. If the value is higher than 1, the sample may not be suitable for measurement by DLS.
TABLE 9
Average effective diameter (nm) | Average polydispersity index | |
IE.1 | 7.13±0.04 | 0.082±0.009 |
IE.2 | 4.57±0.03 | 0.086±0.016 |
IE.3 | 6.84±0.04 | 0.065±0.013 |
IE.4 | 2.23±0.03 | 0.070±0.043 |
IE.5 | 1.61±0.07 | 0.119±0.057 |
IE.6 | 1.59±0.07 | 0.191±0.035 |
Figures 1-6 show the multimodal size distribution of the leave-on oils of examples 1-6 of the present invention.
As can be seen from Table 9 in conjunction with FIGS. 1-6, each of the leave-on oils of examples 1-6 of the present invention achieved an average polydispersity of less than 1. Thus, it was shown that reverse micelles having the average effective diameters as shown in table 9 were formed, and that they were stable in the leave-on oils of examples 1 to 6 of the present invention over time.
Claims (15)
1. A transparent anhydrous composition for conditioning or care of keratin materials, comprising:
a) A continuous oily phase containing at least one oil;
b) A surfactant combination of at least one nonionic surfactant and at least one ionic surfactant; and
C) A dispersed phase containing an organic solvent,
Wherein both the nonionic surfactant and the ionic surfactant are lipophilic.
2. The composition of claim 1, wherein the oil is selected from the group consisting of branched alkane oils containing from 8 to 20 carbon atoms, triglycerides, ether hydrocarbon-based oils having C 8-C12 alkyl groups, polydimethylsiloxane optionally containing dimethylsilanol end groups, and combinations thereof.
3. The composition according to claim 1 or 2, wherein the oil is present in an amount of 80 to 98.5 wt%, preferably 85 to 97.5 wt%, more preferably 88 to 94 wt%, relative to the total weight of the composition.
4. A composition according to any of claims 1-3, wherein the nonionic surfactant has at least one C 6-C22 alkyl chain, preferably a C 12-C22 alkyl chain.
5. The composition of any one of claims 1-4, wherein the nonionic surfactant is present in an amount of 0.01 wt% to 20 wt%, preferably 0.1 wt% to 10 wt%, more preferably 0.1 wt% to 5 wt%, most preferably 0.5 wt% to 4 wt%, relative to the total weight of the composition.
6. The composition of any one of claims 1-5, wherein
The ionic surfactant is selected from the group consisting of anionic surfactants, cationic surfactants, and combinations thereof,
The anionic surfactant has at least one C 6-C22 alkyl chain, preferably two C 6-C22 alkyl chains, more preferably two C 6-C12 alkyl chains;
The cationic surfactant has at least one C 6-C22 alkyl chain, preferably two C 6-C22 alkyl chains, more preferably two C 12-C12 alkyl chains.
7. The composition of any one of claims 1-6, wherein the ionic surfactant is present in an amount of 0.01 wt% to 5wt%, preferably 0.1 wt% to 2wt%, more preferably 0.1 wt% to 1 wt%, relative to the total weight of the composition.
8. The composition of any one of claims 1-7, wherein the organic solvent is selected from organic alcohols.
9. The composition according to any one of claims 1-8, wherein the organic solvent is present in an amount of 0.1 to 10 wt%, preferably 0.2 to 5 wt%, more preferably 0.3 to 2 wt%, relative to the total weight of the composition.
10. The composition according to any one of claims 1-9, further comprising at least one cosmetic active ingredient having a solubility in the organic solvent of not less than 10 g.
11. The composition of claim 10, wherein the cosmetic active ingredient is selected from the group consisting of avobenzone, homosalate, ethylhexyl salicylate, octocrylene, 2-oleamido-1, 3-octadecanediol, N-stearoyl-phytosphingosine, hydroxypalmitoyl dihydrosphingosine, salicylic acid, and combinations thereof.
12. The composition according to claim 10 or 11, wherein the cosmetic active ingredient is present in an amount of 0.001 to 5wt%, preferably 0.01 to 2 wt%, and more preferably 0.1 to 1 wt%, relative to the total weight of the composition.
13. The composition of claim 1, comprising, relative to the total weight of the composition:
a) 88 to 94 weight percent of at least one oil selected from the group consisting of isododecane, dioctyl ether, caprylic/capric triglyceride, polydimethylsiloxane, dimethiconol, and combinations thereof;
b) 0.1 to 1.0 wt% of at least one cationic surfactant selected from dialkyl dimethyl ammonium halides wherein each alkyl group contains 6 to 22 carbon atoms, and 0.1 to 1.0 wt% of at least one nonionic surfactant selected from polyglycerol mono-, di-, or tri-oleates containing 2 to 6 glycerol units, polyglycerol mono-, di-, or tri-isostearates containing 2 to 6 glycerol units, and combinations thereof;
c) 0.3 to 2 weight percent of at least one organic solvent selected from the group consisting of ethanol, octyldodecanol, butylene glycol, dipropylene glycol, propylene glycol, and combinations thereof; and
D) 0.1 to 1 wt% of at least one cosmetic active ingredient selected from avobenzone, homosalate, ethylhexyl salicylate, octocrylene, 2-oleoyl-1, 3-octadecanediol, N-stearoyl-phytosphingosine, hydroxypalmitoyl dihydrosphingosine, salicylic acid, and combinations thereof, wherein both the nonionic surfactant and the cationic surfactant are lipophilic.
14. The composition of any one of claims 1-13, which is a leave-on product.
15. A cosmetic process for conditioning or caring for keratin materials, comprising the application to the keratin materials of a composition as defined in any one of claims 1 to 14.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/CN2021/119901 WO2023044666A1 (en) | 2021-09-23 | 2021-09-23 | Composition for conditioning or caring for keratin materials |
Publications (1)
Publication Number | Publication Date |
---|---|
CN117979945A true CN117979945A (en) | 2024-05-03 |
Family
ID=85601815
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202180102673.6A Pending CN117979945A (en) | 2021-09-23 | 2021-09-23 | Composition for conditioning or caring for keratin materials |
Country Status (3)
Country | Link |
---|---|
CN (1) | CN117979945A (en) |
FR (1) | FR3127132B1 (en) |
WO (1) | WO2023044666A1 (en) |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2779639B1 (en) | 1998-06-15 | 2000-08-04 | Oreal | COSMETIC COMPOSITION CONTAINING A POLYORGANOSILOXANE AND AN ACRYLIC TERPOLYMER AND USE OF THIS COMPOSITION FOR THE TREATMENT OF KERATINIC MATERIALS |
US6440456B1 (en) | 1999-06-09 | 2002-08-27 | L'oreal S.A. | Aqueous carrier systems for lipophilic ingredients |
FR2816834B1 (en) * | 2000-11-20 | 2005-06-24 | Oreal | KERATINIC FIBER TREATMENT COMPOSITION CONSISTING OF A CATIONIC ASSOCIATIVE POLYURETHANE POLYMER AND A PROTECTIVE OR CONDITIONER |
JP3802489B2 (en) * | 2001-02-01 | 2006-07-26 | ザ プロクター アンド ギャンブル カンパニー | Anhydrous cosmetic composition |
US20030103930A1 (en) * | 2001-10-30 | 2003-06-05 | The Procter & Gamble Company | Anhydrous cosmetic compositions containing quaternary ammonium compounds |
FR2892624B1 (en) * | 2005-10-28 | 2009-06-05 | Oreal | COSMETIC COMPOSITION COMPRISING A CATION, A LIQUID FATTY BODY AND A SORBITAN ESTER AND COSMETIC PROCESSING METHOD |
US20080131391A1 (en) * | 2006-12-01 | 2008-06-05 | L'oreal | Compositions containing a quaternary ammonium polymer, a fatty quaternary agent and a nonionic surfactant |
FR3015246B1 (en) * | 2013-12-24 | 2017-10-06 | Oreal | COSMETIC COMPOSITION COMPRISING AN OIL, A NON-IONIC SURFACTANT AND A C-GLYCOSIDE COMPOUND |
-
2021
- 2021-09-23 CN CN202180102673.6A patent/CN117979945A/en active Pending
- 2021-09-23 WO PCT/CN2021/119901 patent/WO2023044666A1/en active Application Filing
- 2021-10-21 FR FR2111174A patent/FR3127132B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2023044666A1 (en) | 2023-03-30 |
FR3127132A1 (en) | 2023-03-24 |
FR3127132B1 (en) | 2024-04-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP7233896B2 (en) | Composition containing two polyglyceryl fatty acid esters | |
KR102626020B1 (en) | Composition containing two types of polyglyceryl fatty acid esters | |
CN110996894A (en) | W/O type emulsion | |
JP2014118400A (en) | Anhydrous cosmetic composition | |
EP3157494B1 (en) | Multi-phase anhydrous composition comprising at least one oil, at least one polyol and non ionic surfactants, and cosmetic process thereof | |
KR20190090841A (en) | Cleansing Suitable Composition | |
KR20190053763A (en) | Cosmetic composition of bigel type | |
CN116419743A (en) | Composition for conditioning and/or dyeing keratin fibres | |
JP2014118399A (en) | Anhydrous cosmetic composition | |
JP2017100985A (en) | Composition suitable for cosmetic use | |
DE102015225554A1 (en) | "Means for Temporarily Deforming Keratin-containing Fibers with Preservative III" | |
CN111050744A (en) | Hair cosmetic | |
CN117979945A (en) | Composition for conditioning or caring for keratin materials | |
WO2023280485A1 (en) | Transforming hair care product | |
US20220273552A1 (en) | Hair cosmetic compositions | |
EP3411007A1 (en) | Water-in-oil emulsions which are based on cetyl diglyceryl tris(trimethylsiloxy)silyl ethyl dimethicone as emulsifier and are largely silicone oil-free | |
KR20200139252A (en) | New composite and emulsion composition | |
WO2023133795A1 (en) | Composition for conditioning keratin fibers | |
DE102015225558A1 (en) | Means for the temporary deformation of keratin-containing fibers with preservative II | |
WO2022068473A1 (en) | Composition for conditioning and/or dyeing keratin fibers | |
KR20190068590A (en) | Non-tacky stable composition | |
WO2024130576A1 (en) | Composition for conditioning keratin fibers | |
DE102015225557A1 (en) | Means for temporary deformation of keratin-containing fibers with preservative I | |
CN116490162A (en) | Two-phase composition | |
WO2016091456A1 (en) | Silicone-containing cosmetic agent |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination |