CN117887804A - 用于识别或量化在生物样品中的靶标的方法和组合物 - Google Patents

用于识别或量化在生物样品中的靶标的方法和组合物 Download PDF

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CN117887804A
CN117887804A CN202311572899.XA CN202311572899A CN117887804A CN 117887804 A CN117887804 A CN 117887804A CN 202311572899 A CN202311572899 A CN 202311572899A CN 117887804 A CN117887804 A CN 117887804A
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construct
sequence
oligonucleotide
ligand
anchor
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马龙·斯托基斯
皮特·斯密博特
布莱恩·侯克-卢米斯
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New York Genome Center Inc
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New York Genome Center Inc
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1093General methods of preparing gene libraries, not provided for in other subgroups
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804Nucleic acid analysis using immunogens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/06Biochemical methods, e.g. using enzymes or whole viable microorganisms

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
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  • Wood Science & Technology (AREA)
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  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
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  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
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  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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CN202311572899.XA 2017-02-02 2018-02-02 用于识别或量化在生物样品中的靶标的方法和组合物 Pending CN117887804A (zh)

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US201762453726P 2017-02-02 2017-02-02
US62/453,726 2017-02-02
US201762515180P 2017-06-05 2017-06-05
US62/515,180 2017-06-05
US201762549189P 2017-08-23 2017-08-23
US62/549,189 2017-08-23
US201762559228P 2017-09-15 2017-09-15
US62/559,228 2017-09-15
US201762599450P 2017-12-15 2017-12-15
US62/599,450 2017-12-15
US201762609332P 2017-12-21 2017-12-21
US62/609,332 2017-12-21
PCT/US2018/016587 WO2018144813A1 (fr) 2017-02-02 2018-02-02 Procédés et compositions permettant d'identifier ou de quantifier des cibles dans un échantillon biologique
CN201880022775.5A CN110475864B (zh) 2017-02-02 2018-02-02 用于识别或量化在生物样品中的靶标的方法和组合物

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US (2) US20180251825A1 (fr)
EP (2) EP4324931A3 (fr)
CN (2) CN117887804A (fr)
DK (1) DK3583214T3 (fr)
ES (1) ES2968290T3 (fr)
FI (1) FI3583214T3 (fr)
WO (1) WO2018144813A1 (fr)

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US20180251825A1 (en) 2018-09-06
CN110475864B (zh) 2024-01-12
CN110475864A (zh) 2019-11-19
EP3583214A1 (fr) 2019-12-25
EP4324931A2 (fr) 2024-02-21
EP3583214B1 (fr) 2023-11-22
DK3583214T3 (da) 2023-12-18
FI3583214T3 (fi) 2023-12-19
EP3583214A4 (fr) 2020-12-23
EP4324931A3 (fr) 2024-05-29
WO2018144813A1 (fr) 2018-08-09
US20210371914A1 (en) 2021-12-02
ES2968290T3 (es) 2024-05-08

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