CN117801947A - High-pressure cell culture cabin with quick opening and quick closing functions - Google Patents
High-pressure cell culture cabin with quick opening and quick closing functions Download PDFInfo
- Publication number
- CN117801947A CN117801947A CN202311271372.3A CN202311271372A CN117801947A CN 117801947 A CN117801947 A CN 117801947A CN 202311271372 A CN202311271372 A CN 202311271372A CN 117801947 A CN117801947 A CN 117801947A
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- Prior art keywords
- cabin
- cabin door
- flap
- rod
- cell culture
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- 238000004113 cell culture Methods 0.000 title claims abstract description 33
- 230000000670 limiting effect Effects 0.000 claims abstract description 66
- 210000001503 joint Anatomy 0.000 claims abstract description 4
- 241000446313 Lamella Species 0.000 description 6
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/46—Means for fastening
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/48—Holding appliances; Racks; Supports
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Clinical Laboratory Science (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention discloses a high-pressure cell culture cabin with a quick opening and quick closing function, which is characterized in that a cabin door is pushed to a cabin opening direction, a rotating shaft rotates, the cabin door is closed, an opening of the cabin door is in butt joint with the cabin opening, the opening of the cabin door is accommodated in a three-flap clamp, a rotating rod rotates, under the drive of forward and reverse screw teeth, a first flap part and a second flap part of the three-flap clamp relatively move to be close to each other so as to realize clamping of the cabin door by the three-flap clamp, a moving block moves forwards slightly, a left limiting rod and a right limiting rod penetrate through a long strip hole of the limiting block, the left limiting rod is just limited at the left end of the long strip hole, and the right limiting rod is just limited at the right end of the long strip hole, so that the cabin door is quickly closed; the moving block moves backwards slightly, the left limiting rod and the right limiting rod do not penetrate through the strip holes of the limiting block, the rotating rod rotates reversely, the first valve part and the second valve part of the three-valve clamp move away reversely under the drive of forward and reverse screw teeth, the cabin door is pushed to the direction away from the hatch, the rotating shaft rotates, the cabin door is opened, and therefore the cabin door is opened rapidly.
Description
Technical Field
The invention relates to the technical field of cell culture devices, in particular to a high-pressure cell culture cabin with a quick opening and closing function.
Background
The utility model discloses a high-pressure cell culture cabin has been jointly designed before this unit and the university and patent has been filed, and the application number is 2018115822134, and this high-pressure cell culture cabin's hatch door and cabin's fixed knot construct is: bolt bayonets are respectively arranged on the extending fixed angles of the four corners of the cabin door, bolt seats are respectively arranged at the four corner positions of the cabin body corresponding to the cabin door frame of the cabin door, bolts are pivoted in the bolt seats, and the movable ends of the bolts are clamped into the bolt bayonets and locked through nuts, so that the cabin door is tightly fastened outside the cabin door frame of the cabin body. When the cabin door needs to be closed, the movable ends of the four bolts are required to be clamped into corresponding bolt bayonets respectively, and nuts on the four bolts are locked to close the cabin door. When the cabin door needs to be opened, the bolts at four corner positions need to be unscrewed one by one, and then the movable ends of the four bolts are pulled out from the corresponding bolt bayonets respectively, so that the cabin door can be opened. The door closing and door opening operations are cumbersome. The invention designs a quick opening and closing structure, so that a cabin door can be opened and closed quickly.
Disclosure of Invention
Aiming at the problems and the defects existing in the prior art, the invention provides a novel high-pressure cell culture cabin with the functions of quick opening and quick closing.
The invention solves the technical problems by the following technical proposal:
the invention provides a high-pressure cell culture cabin with a quick opening and quick closing function, which is characterized in that the high-pressure cell culture cabin is of a horizontal cylindrical single cabin one-door structure and comprises a cabin body, one end of the cabin body adopts a standard elliptical head, a fixed ring frame is sleeved and fixed at the other end of the cabin body, a hatch is arranged at the other end of the cabin body, a three-flap clamp is fixed on the fixed ring frame along the edge of the hatch, a left limit rod is fixed on the outer side of the top of a first flap part of the three-flap clamp, a right limit rod is fixed on the outer side of the top of a second flap part of the three-flap clamp, a left-falling U-shaped movable frame is fixed on the outer surface of the top of the first flap part of the three-flap clamp, a right-falling U-shaped movable frame is fixed on the outer surface of the top of the second flap part of the three-flap clamp, a rotary rod is arranged on the top of the left-falling U-shaped movable frame in a penetrating manner, a forward screw tooth is arranged on the left part of the rotary rod, a reverse screw tooth is arranged on the top of the left-falling U-shaped movable frame, and the top of the rotary rod is positioned on the reverse screw tooth.
Two fixing bases are fixed at one side middle position of the fixing ring frame and close to the three-flap type clamp position at intervals, two vertical fixing rods are fixed between the fixing bases, rotating shafts are respectively sleeved on the upper portion and the lower portion of the vertical fixing rods, the rotating shafts are fixedly connected with oval cabin doors through connecting blocks, fixing columns are fixed to the tops of the cabin doors, limiting rings are fixedly sleeved on the fixing columns, moving blocks are sleeved on the fixing columns, the moving blocks are limited between the limiting rings and the tops of the cabin doors, waist-shaped holes are formed in the moving blocks so that the moving blocks can move back and forth on the fixing columns, limiting blocks are fixed to the front ends of the moving blocks, and long strip holes are formed in the limiting blocks.
The hatch door is pushed towards the hatch direction, the rotation shaft rotates, the hatch door is closed, the opening of the hatch door is in butt joint with the hatch door, the opening of the hatch door is contained in the three-flap type clamp, the rotation rod rotates, under the driving of the forward screw thread and the reverse screw thread, the relative movement of the first flap part and the second flap part of the three-flap type clamp is close to the hatch door so as to realize three-flap type clamp clamping, the moving block moves forward slightly, the left limiting rod and the right limiting rod penetrate through the long strip hole of the limiting block, the left limiting rod is just limited at the left end of the long strip hole of the limiting block, and the right limiting rod is just limited at the right end of the long strip hole of the limiting block, so that the hatch door can be closed quickly.
The moving block is moved backwards slightly, the left limiting rod and the right limiting rod do not penetrate through the long strip holes of the limiting block, the rotating rod is rotated reversely, the first valve part and the second valve part of the three-valve clamp are moved away reversely under the drive of the forward screw tooth and the reverse screw tooth, the cabin door is pushed away from the hatch direction, the rotating shaft is rotated, the cabin door is opened, and therefore the cabin door is opened rapidly.
When the cabin door is required to be closed, the cabin door can be quickly closed only by rotating the rotating rod to enable the three-flap type clamp to clamp the cabin door and then slightly moving the moving block forwards to enable the left limiting rod and the right limiting rod on the three-flap type clamp to be limited in the strip hole of the limiting block. When the cabin door needs to be opened, only the moving block is required to be moved backwards slightly so that the left limiting rod and the right limiting rod are not arranged in the long hole of the limiting block, the three-flap type clamp is enabled to loosen the cabin door by rotating the rotating rod reversely, the operation is relatively simple, and the cabin door can be opened and closed quickly.
Drawings
FIGS. 1 to 3 are schematic perspective views showing a high-pressure cell culture chamber with a quick opening and closing function according to a preferred embodiment of the present invention.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments of the present invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
As shown in fig. 1-3, this embodiment provides a high-pressure cell culture chamber with quick opening and quick closing functions, the high-pressure cell culture chamber is of a horizontal cylindrical single chamber one-door structure, one end of the high-pressure cell culture chamber adopts a standard elliptical head, the material steel grade of the high-pressure cell culture chamber is 16MnR, the design pressure of the high-pressure cell culture chamber is 2.5MPa, and the highest working pressure is 2MPa.
The high-pressure cell culture cabin comprises a cabin body 1, one end of the cabin body 1 is provided with a standard elliptical head, the other end of the cabin body 1 is sleeved and fixed with a fixed ring frame 2, the other end of the cabin body is provided with a hatch 3, a three-flap clamp 4 is fixed on the fixed ring frame 2 along the edge of the hatch 3, a left limit rod 5 is fixed on the outer side of the top of a first flap part of the three-flap clamp 4, a right limit rod 6 is fixed on the outer side of the top of a second flap part, a left inverted U-shaped movable frame 7 is fixed on the outer surface of the top of the first flap part of the three-flap clamp 4, a right inverted U-shaped movable frame 8 is fixed on the outer surface of the top of the first flap part of the three-flap clamp 4, a rotary rod 9 is arranged on the top of the left inverted U-shaped movable frame 7 and the top of the right inverted U-shaped movable frame 8 in a penetrating manner, a rotary rod 9 is arranged on the left inverted U-shaped movable frame, a left inverted screw tooth is arranged on the left portion of the rotary rod 9, a right inverted screw tooth is arranged on the left side of the rotary rod 9 (not shown in the figure, the right screw tooth is an existing part, the right screw tooth is fixed on the right side of the existing part), the right screw tooth is the right screw cover is the existing part), the left inverted screw tooth is arranged on the left side of the front screw cover is the front cover, the left screw cover is arranged on the front cover 10, the left cover is arranged on the front cover 10, and the blind cover is arranged on the blind cover is the front cover, and the left cover is the cover.
Two fixing bases 21 are fixed at the right middle position of the fixing ring frame 2 and close to the position of the three-flap clamp 4 at intervals, a vertical fixing rod 11 is fixed between the two fixing bases 21, rotating shafts 12 are respectively sleeved on the upper and lower parts of the vertical fixing rod 11, the two rotating shafts 12 are fixedly connected with an elliptic cabin door 14 through a connecting block 13, a fixing column 15 is fixed on the top of the cabin door 14, a limiting ring 16 is fixedly sleeved on the fixing column 15, the fixing column 15 and the limiting ring 16 are integrally formed, a moving block 17 is sleeved on the fixing column 15, the moving block 17 is limited between the limiting ring 16 and the top of the cabin door 14, a waist-shaped hole 18 is formed in the moving block 17 so that the moving block 17 moves back and forth on the fixing column 15, a limiting block 19 is fixed at the front end of the moving block 17, and a strip-shaped hole 20 is formed in the limiting block 19.
The cell culture tray 22 is arranged in the cabin body 1 along the length direction, the cell culture tray 22 is hollow, for example, sliding grooves are formed in the opposite side walls of the cabin body 1 along the length direction, sliding blocks matched with the sliding grooves are arranged on two sides of the cell culture tray 22, so that the cell culture tray 22 can slide along the corresponding sliding grooves, and the cell culture tray 22 can be conveniently taken out of the cabin body 1 or put into the cabin body 1.
The inside of the cabin body 1 is provided with a sliding type collecting tray 23 along the length direction and below the cell culture tray 22, the collecting tray 23 is used for collecting sundries generated in the cell culture above, for example, the opposite side walls in the cabin body 1 are provided with sliding grooves along the length direction, two sides of the collecting tray 23 are provided with sliding blocks matched with the sliding grooves, so that the collecting tray 23 can slide along the corresponding sliding grooves, and the collecting tray 23 is convenient to take out the cabin body 1 or put into the cabin body 1.
The cabin door 14 is pushed towards the direction of the hatch 3, the rotating shaft 12 rotates, the cabin door 14 is closed, the opening of the cabin door 14 is in butt joint with the hatch 3, the opening of the cabin door 14 is contained in the three-flap type clamp 4, the rotating rod 9 rotates, under the drive of the forward screw thread and the reverse screw thread, the first flap part and the second flap part of the three-flap type clamp 4 move relatively to be close to each other so as to realize clamping of the cabin door 14 by the three-flap type clamp 4, the moving block 17 moves forwards slightly, the left limiting rod 5 and the right limiting rod 6 penetrate through the long strip hole 20 of the limiting block 19, the left limiting rod 5 is just limited at the left end of the long strip hole 20 of the limiting block, and the right limiting rod 6 is just limited at the right end of the long strip hole 20 of the limiting block, so that the cabin door 14 can be closed quickly.
The moving block 17 is moved backwards slightly, the left limiting rod 5 and the right limiting rod 6 do not penetrate through the long strip holes 20 of the limiting block 19, the rotating rod 9 is rotated reversely, the first valve part and the second valve part of the three-valve clamp 4 are moved away reversely under the drive of the forward screw tooth and the reverse screw tooth, the cabin door 14 is pushed towards the direction away from the hatch 3, the rotating shaft 12 is rotated, the cabin door 14 is opened, and therefore the cabin door 14 is opened rapidly.
In this scheme, the shape of left gag lever post 5 matches with the left end shape of rectangular hole 20 of stopper 19, and the shape of right gag lever post 6 matches with the right end shape of rectangular hole 20 of stopper 19 for left gag lever post 5 and right gag lever post 6 can realize better spacing with the left and right sides end of rectangular hole 20 of stopper 19.
In this scheme, through rotatory rotary rod 9 for three lamella clamp 4 chucking hatch door 14, owing to left gag lever post 5 and right gag lever post 6 on the three lamella clamp 4 are spacing in stopper 19's rectangular hole 20, so even three lamella clamp 4 is impacted to the high pressure in the cabin body 1, and three lamella clamp 4 under the limiting action also can not loosen on both sides about, and the hatch door 14 is held in the card that can be tight all the time, thereby makes the hatch door can tightly lock.
In this scheme, when needs closed hatch door 1, only need rotatory rotary rod 9 make three lamella clamp 4 chucking hatch door 14, and the back moves slightly and makes left gag lever post 5 and right gag lever post 6 on the three lamella clamp 4 spacing in the rectangular hole 20 of stopper 19, can close hatch door 14 fast. When the cabin door 1 needs to be opened, only the moving block 17 is required to be moved backwards slightly so that the left limiting rod 5 and the right limiting rod 6 are not in the long strip holes 20 of the limiting block 19, the rotary rod 9 is rotated reversely so that the three-flap type clamp 4 loosens the cabin door 14, the operation is relatively simple, and the cabin door can be opened and closed quickly.
While specific embodiments of the invention have been described above, it will be appreciated by those skilled in the art that these are by way of example only, and the scope of the invention is defined by the appended claims. Various changes and modifications to these embodiments may be made by those skilled in the art without departing from the principles and spirit of the invention, but such changes and modifications fall within the scope of the invention.
Claims (6)
1. The high-pressure cell culture cabin is of a horizontal cylindrical single cabin one-door structure and comprises a cabin body, one end of the cabin body is provided with a standard elliptical head, the other end of the cabin body is sleeved and fixed with a fixed ring frame, the other end of the cabin body is provided with a hatch, a three-flap clamp is fixed on the fixed ring frame along the edge of the hatch, a left limit rod is fixed on the outer side of the top of a first flap part of the three-flap clamp, a right limit rod is fixed on the outer side of the top of a second flap part of the three-flap clamp, a left-falling U-shaped movable frame is fixed on the outer surface of the top of the first flap part of the three-flap clamp, a right-falling U-shaped movable frame is fixed on the outer surface of the top of the second flap part of the three-flap clamp, a rotary rod is penetrated and arranged on the top of the left-falling U-shaped movable frame, a forward screw tooth is arranged on the left part of the rotary rod, a reverse screw tooth is arranged on the top of the left-falling U-shaped movable frame, and the top of the right-falling U-shaped movable frame is positioned on the reverse screw tooth;
two fixing bases are fixed at one side middle position of the fixing ring frame and close to the three-flap type clamp, a vertical fixing rod is fixed between the two fixing bases, a rotating shaft is sleeved on the upper portion and the lower portion of the vertical fixing rod respectively, the two rotating shafts are fixedly connected with an oval cabin door through a connecting block, a fixing column is fixed on the top of the cabin door, a limiting ring is sleeved on the fixing column, a moving block is sleeved on the fixing column, the moving block is limited between the limiting ring and the top of the cabin door, a waist-shaped hole is formed in the moving block so that the moving block moves back and forth on the fixing column, a limiting block is fixed at the front end of the moving block, and a strip hole is formed in the limiting block;
the cabin door is pushed to the direction of the hatch, the rotating shaft rotates, the cabin door is closed, the opening of the cabin door is in butt joint with the hatch, the opening of the cabin door is accommodated in a three-flap type clamp, the rotating rod is rotated, under the drive of the forward screw thread and the reverse screw thread, the first flap part and the second flap part of the three-flap type clamp move relatively to approach to realize clamping of the cabin door by the three-flap type clamp, the moving block moves forward slightly, the left limiting rod and the right limiting rod penetrate through strip holes of the limiting block, the left limiting rod is just limited at the left end of the strip holes of the limiting block, and the right limiting rod is just limited at the right end of the strip holes of the limiting block, so that the cabin door is closed rapidly;
the moving block is moved backwards slightly, the left limiting rod and the right limiting rod do not penetrate through the long strip holes of the limiting block, the rotating rod is rotated reversely, the first valve part and the second valve part of the three-valve clamp are moved away reversely under the drive of the forward screw tooth and the reverse screw tooth, the cabin door is pushed away from the hatch direction, the rotating shaft is rotated, the cabin door is opened, and therefore the cabin door is opened rapidly.
2. The high-pressure cell culture chamber with the quick opening and quick closing functions according to claim 1, wherein the rotating rod cover is provided with a blind plate cover, the left side of the blind plate cover is sleeved on the left side of the rotating rod, and the right side of the blind plate cover is sleeved on the right side of the rotating rod.
3. The high pressure cell culture chamber with the quick opening and quick closing function according to claim 1, wherein the fixing column and the limiting ring are integrally formed.
4. The high-pressure cell culture chamber with the quick opening and quick closing functions according to claim 1, wherein a sliding cell culture tray is arranged in the chamber body along the length direction, and the cell culture tray is hollow.
5. The high-pressure cell culture chamber with the quick opening and quick closing function according to claim 4, wherein a sliding collecting tray is arranged in the chamber body along the length direction and below the cell culture tray.
6. The high-pressure cell culture chamber with the quick opening and quick closing function according to claim 1, wherein the shape of the left limiting rod is matched with the shape of the left end of the long strip hole of the limiting block, and the shape of the right limiting rod is matched with the shape of the right end of the long strip hole of the limiting block.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311271372.3A CN117801947A (en) | 2023-09-28 | 2023-09-28 | High-pressure cell culture cabin with quick opening and quick closing functions |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311271372.3A CN117801947A (en) | 2023-09-28 | 2023-09-28 | High-pressure cell culture cabin with quick opening and quick closing functions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN117801947A true CN117801947A (en) | 2024-04-02 |
Family
ID=90418764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311271372.3A Pending CN117801947A (en) | 2023-09-28 | 2023-09-28 | High-pressure cell culture cabin with quick opening and quick closing functions |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN117801947A (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202790511U (en) * | 2012-07-27 | 2013-03-13 | 中国石油化工股份有限公司 | Quickly-opened blind plate |
| CN102978112A (en) * | 2012-11-28 | 2013-03-20 | 中国人民解放军海军医学研究所 | High-pressure cell incubator, temperature control method and pressure control method thereof |
| CN109373099A (en) * | 2018-12-18 | 2019-02-22 | 沧州隆泰迪管道科技有限公司 | Pintongs clamp-type quick opening blind plate and application method |
| CN109628303A (en) * | 2018-12-24 | 2019-04-16 | 中国人民解放军第二军医大学 | A kind of high pressure cell culture cabin |
| CN210533893U (en) * | 2019-08-29 | 2020-05-15 | 青岛海洋工程水下设备检测有限公司 | Internal and external pressure testing device for simulation deep sea equipment |
| CN113958710A (en) * | 2021-11-04 | 2022-01-21 | 中国海洋石油集团有限公司 | High-pressure cabin sealed by clamp quick-opening type fixed end cover and control method |
| US20230126924A1 (en) * | 2021-10-25 | 2023-04-27 | Jeffrey L. Maichel | Valve insertion tool |
-
2023
- 2023-09-28 CN CN202311271372.3A patent/CN117801947A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202790511U (en) * | 2012-07-27 | 2013-03-13 | 中国石油化工股份有限公司 | Quickly-opened blind plate |
| CN102978112A (en) * | 2012-11-28 | 2013-03-20 | 中国人民解放军海军医学研究所 | High-pressure cell incubator, temperature control method and pressure control method thereof |
| CN109373099A (en) * | 2018-12-18 | 2019-02-22 | 沧州隆泰迪管道科技有限公司 | Pintongs clamp-type quick opening blind plate and application method |
| CN109628303A (en) * | 2018-12-24 | 2019-04-16 | 中国人民解放军第二军医大学 | A kind of high pressure cell culture cabin |
| CN210533893U (en) * | 2019-08-29 | 2020-05-15 | 青岛海洋工程水下设备检测有限公司 | Internal and external pressure testing device for simulation deep sea equipment |
| US20230126924A1 (en) * | 2021-10-25 | 2023-04-27 | Jeffrey L. Maichel | Valve insertion tool |
| CN113958710A (en) * | 2021-11-04 | 2022-01-21 | 中国海洋石油集团有限公司 | High-pressure cabin sealed by clamp quick-opening type fixed end cover and control method |
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