CN117653325A - Ultra-wideband continuous variable frequency microwave ablation system and control method thereof - Google Patents

Ultra-wideband continuous variable frequency microwave ablation system and control method thereof Download PDF

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Publication number
CN117653325A
CN117653325A CN202311714213.6A CN202311714213A CN117653325A CN 117653325 A CN117653325 A CN 117653325A CN 202311714213 A CN202311714213 A CN 202311714213A CN 117653325 A CN117653325 A CN 117653325A
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China
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microwave
microwave ablation
impedance matching
computer
ablation antenna
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薛泉
王宇琦
廖绍伟
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South China University of Technology SCUT
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South China University of Technology SCUT
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Priority to CN202311714213.6A priority Critical patent/CN117653325A/en
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02DCLIMATE CHANGE MITIGATION TECHNOLOGIES IN INFORMATION AND COMMUNICATION TECHNOLOGIES [ICT], I.E. INFORMATION AND COMMUNICATION TECHNOLOGIES AIMING AT THE REDUCTION OF THEIR OWN ENERGY USE
    • Y02D30/00Reducing energy consumption in communication networks
    • Y02D30/70Reducing energy consumption in communication networks in wireless communication networks

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Abstract

The application discloses ultra-wideband continuous variable frequency microwave ablation system and control method thereof, the system comprises: the microwave source is used for generating microwave energy; the directional coupler is used for transmitting microwave energy to the microwave ablation antenna; the microwave ablation antenna is used for electromagnetic radiation by utilizing microwave energy; the power meter system is used for measuring the microwave energy; transmitting the measurement result to a computer; the computer is used for determining the impedance matching degree of the microwave ablation antenna according to the measurement result; when the impedance matching degree is lower than a preset threshold value, control signals of different frequency bands are sequentially sent to the microwave source so as to improve the impedance matching degree; when the impedance matching degree reaches a preset target value, the frequency band of the control signal is maintained at the current frequency band, and the control signal of the current frequency band is continuously sent to the microwave source. The method can realize the broadband operation and continuous frequency adjustment of the microwave ablation system, and can be widely applied to the technical fields of microwaves and antennas.

Description

Ultra-wideband continuous variable frequency microwave ablation system and control method thereof
Technical Field
The application relates to the technical field of microwaves and antennas, in particular to an ultra-wideband continuous variable frequency microwave ablation system and a control method thereof.
Background
The traditional microwave ablation technology relies on two key devices, namely a microwave ablation instrument and a microwave ablation antenna. The microwave ablation instrument in the prior art is a high-power microwave single-frequency point or double-frequency point ablation instrument, and cannot realize the functions of broadband and continuous frequency adjustment. The existing microwave ablation antenna is also limited to a design of single frequency point or combination of a plurality of single frequency points, and cannot realize broadband operation. Heretofore, microwave ablation antennas have been mainly focused on designing monopole, dipole, and slot aperture antennas on a coaxial line, and functionally focused on choke design and design for roundness control of the ablation range, which are usually realized by loading sleeves, choke rings, balun, and the like. Therefore, the design form of the microwave ablation antenna is single, the function is deficient, and the influence caused by the real-time change of the microwave ablation process is difficult to deal with.
Disclosure of Invention
In view of the above, the present application provides an ultra-wideband continuous variable frequency microwave ablation system and a control method thereof, so as to implement wideband operation and continuous frequency adjustment of the microwave ablation system.
An aspect of the present application provides an ultra-wideband continuous variable frequency microwave ablation system, comprising: a microwave source, a directional coupler, a microwave ablation antenna, a power meter system, and a computer;
the directional coupler is respectively connected with the microwave source, the microwave ablation antenna and the power meter system; the computer is respectively connected with the microwave source and the power meter system;
the microwave source is used for generating microwave energy;
the directional coupler is used for transmitting the microwave energy to the microwave ablation antenna;
the microwave ablation antenna is used for carrying out electromagnetic radiation by utilizing the microwave energy;
the power meter system is used for measuring the microwave energy; transmitting the measurement results to the computer;
the computer is used for determining the impedance matching degree of the microwave ablation antenna according to the measurement result; when the impedance matching degree is lower than a preset threshold value, control signals of different frequency bands are sequentially sent to the microwave source so as to improve the impedance matching degree; when the impedance matching degree reaches a preset target value, the frequency band of the control signal is maintained at the current frequency band, and the control signal of the current frequency band is continuously sent to the microwave source.
Optionally, the microwave source comprises a signal generator and a power amplifier; the signal generator is connected with the power amplifier;
wherein the computer is connected with the signal generator, and the power amplifier is connected with the directional coupler;
the signal generator is used for generating a microwave signal;
the power amplifier is used for amplifying the microwave signal to obtain the microwave energy.
Optionally, the microwave ablation system further comprises an analog-to-digital conversion device;
one end of the analog-to-digital conversion device is connected with the power meter system, and the other end of the analog-to-digital conversion device is connected with the computer;
the analog-to-digital conversion device is used for converting the measurement result of the analog signal into a digital signal and then transmitting the digital signal to the computer.
Optionally, the directional coupler includes a first port, a second port, a third port, and a fourth port;
the power meter system comprises a first power meter and a second power meter;
wherein the power amplifier is connected with the directional coupler through the first port; the microwave ablation antenna is connected with the directional coupler through the second port;
the first power meter is connected with the directional coupler through the third port, and the second power meter is connected with the directional coupler through the fourth port;
the first power meter is used for measuring the microwave energy in and out of the microwave ablation antenna;
the second power meter is used for measuring the microwave energy in and out of the power amplifier.
Optionally, the whole structure of the microwave ablation antenna is needle-shaped;
the microwave ablation antenna sequentially comprises a top metal layer, an upper dielectric layer, a solidified layer, an inner metal layer, a bottom dielectric layer and a bottom metal layer from top to bottom;
the tail part of the microwave ablation antenna is a feed end, and the feed end is connected with the directional coupler; the head of the microwave ablation antenna is needle-shaped;
the tail parts of the top metal layer, the upper medium layer, the solidified layer, the inner metal layer, the bottom medium layer and the bottom metal layer are wider than the diameter of the needle-shaped microwave ablation antenna.
Optionally, the outer wall of the needle body of the microwave ablation antenna is provided with a plurality of circles of annular grooves;
the annular grooves are arranged below the head of the microwave ablation antenna;
the metal width of the inner metal layer at the annular groove position is wider than that of the inner metal layer at other positions.
Another aspect of the present application further provides a control method of an ultra-wideband continuous variable frequency microwave ablation system, including:
a computer for use in an ultra-wideband continuous variable frequency microwave ablation system as described above, the method comprising:
obtaining a measurement result of the microwave energy;
determining the impedance matching degree of the microwave ablation antenna according to the measurement result;
when the impedance matching degree is lower than a preset threshold value, control signals of different frequency bands are sequentially sent to a microwave source so as to improve the impedance matching degree;
when the impedance matching degree reaches a preset target value, the frequency band of the control signal is maintained at the current frequency band, and the control signal of the current frequency band is continuously sent to the microwave source.
Optionally, the determining the impedance matching degree of the microwave ablation antenna according to the measurement result includes:
determining an analog signal corresponding to the measurement result of the digital signal according to a preset mapping relation;
and determining the impedance matching degree of the microwave ablation antenna according to the analog signal.
Another aspect of the present application also provides an electronic device, including a processor and a memory;
the memory is used for storing programs;
the processor executes the program to implement the method.
Another aspect of the present application also provides a computer-readable storage medium storing a program that is executed by a processor to implement the method.
The application also discloses a computer program product or a computer program comprising computer instructions stored in a computer readable storage medium. The computer instructions may be read from a computer-readable storage medium by a processor of an electronic device, and executed by the processor, cause the electronic device to perform the method described above.
The application at least comprises the following beneficial effects:
1) The method utilizes the broadband method and is assisted by a closed-loop automatic system in a microwave ablation system to automatically convert frequency in real time, so that the problems of poor ablation efficiency and effect and uncontrollable ablation caused by impedance mismatch under the single-frequency point working condition are solved.
2) According to the method, the effect of controlling the power transmission efficiency of the microwave ablation system process is controlled according to automatic real-time variable frequency regulation, and the phenomenon that the manual regulation causes misoperation or judgment errors is avoided.
3) The microwave ablation system is not used by separating a single design and combining the single design as in the prior design scheme, but combines a microwave source and a microwave ablation antenna, thereby realizing the customization of a required frequency band.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are needed in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
Fig. 1 is a schematic structural diagram of an ultra-wideband continuous variable frequency microwave ablation system according to an embodiment of the present application;
fig. 2 is a diagram of an alternative structural example of an ultra-wideband continuous variable frequency microwave ablation system according to an embodiment of the present application;
FIG. 3 is an exemplary diagram of a microwave source provided in an embodiment of the present application;
fig. 4 is a structural example diagram of a directional coupler according to an embodiment of the present application;
fig. 5 is a structural example diagram of a microwave ablation antenna according to an embodiment of the present application;
FIG. 6 is an example diagram of a power system provided by an embodiment of the present application;
FIG. 7 is a schematic diagram of a computer controlled microwave ablation system according to an embodiment of the present application;
fig. 8 is a schematic view of a partial scenario of a microwave ablation system for treating a tumor according to an embodiment of the present application.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, the present application will be further described in detail with reference to the accompanying drawings and examples. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the present application.
It should be noted that although functional block division is performed in a device diagram and a logic sequence is shown in a flowchart, in some cases, the steps shown or described may be performed in a different order than the block division in the device, or in the flowchart.
The terms first, second and the like in the description and in the claims and in the above-described figures, are used for distinguishing between similar elements and not necessarily for describing a particular sequential or chronological order. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used herein is for the purpose of describing embodiments of the present application only and is not intended to be limiting of the present application.
To facilitate understanding of the embodiments of the present application, the related art to which the embodiments of the present application may relate will be explained:
the microwave ablation technology is a minimally invasive treatment technology which utilizes molecular-level dipole orientation motion with the frequency of hundred megahertz and above, and friction heat generation causes coagulation necrosis of tissue cells, and the microwave ablation system is a research hot spot of the current malignant tumor treatment, has high tolerance and repeated treatment by virtue of small invasiveness and large ablation range, and plays outstanding advantages of longer survival time, lower recurrence rate and fewer complications in clinical treatment of unresectable malignant tumors (liver, bone, lung, kidney), arrhythmia, neuromodulation, endometrium excision and the like.
Microwave ablation technology is a complex technology of traditional electromagnetic and biomedical interaction, and the commonality and difference of electromagnetic wave propagation in free space and biological tissues make establishment of electromagnetic microscopic mechanisms of human tissues and understanding of microscopic particle responses become keys for the development of the technology. The traditional microwave ablation technology originates from radiofrequency ablation, and the working principle of radiofrequency ablation depends on the impedance of tissues around an electrode to radiofrequency, so that the problems of carbonization of tissues and evaporation of water in the ablation process, great influence of vascular heat sink effect around the tissues, incomplete ablation, limited ablation range, easy recurrence after operation and the like are gradually replaced by the microwave ablation technology. The microwave ablation technology benefits from the principle of active heating, and the self dipole molecules of the tissue generate heat through polarity inversion of the self dipole molecules back and forth along with the frequency under the microwave frequency, so that the heating efficiency of the microwave ablation technology is not affected excessively even if the microwave ablation technology is adjacent to a blood vessel in the treatment process.
For the microwave ablation process, the tumor invades into the tumor through the microwave ablation antenna to heat the microwave energy, and the temperature rises, so that a series of complex medium changes such as water evaporation, tissue carbonization, protein denaturation and the like occur in the tissue in an ablation range, and the series of changes can adversely affect the heating effect of the microwave ablation antenna on the tumor. In addition, different penetration depths of the ablation antenna, different organ tumors, and even different individuals with different fat and moisture contents can cause corresponding changes in electromagnetic medium, which also presents great challenges for the design of the microwave ablation antenna. If the influence of the change of the tissue along with the ablation process cannot be overcome, such as complex dielectric constant, attenuation constant, electrical conductivity, thermal conductivity, specific heat capacity, tissue strength and the like are changed, the impedance mismatch of the microwave ablation antenna is caused, so that the backward radiation is enhanced, the ablation needle tube is overheated and scalds the skin, the ablation time is prolonged, the ablation is incomplete and the like, and the microwave ablation technology is difficult to further develop and maintain the market position.
Traditional microwave ablation systems: the microwave ablation device consists of a microwave ablation instrument with single frequency points or multiple frequency points and a microwave ablation antenna. Most of the ablation antennas are large in size and high in invasiveness, so that the patient tolerance is poor; the design is complex, and the design such as balun or sleeve is usually used for restricting reverse current, or the liquid cooling or air cooling device is used for cooling the needle tube in real time to avoid scalding the skin. However, the problem of bidirectional coupling caused by tissue change in the ablation process is difficult to fundamentally solve and overcome, so that the application is limited, the clinical use and operation difficulties are high, and the risk is high.
Based on this, the technical problem to be solved by the present application includes:
1) The size of the ultra-wideband microwave ablation antenna is reduced to be matched with an ultra-wideband ablation system;
2) The design of the ultra-wideband microwave source is matched with an ultra-wideband ablation system;
3) The problems of serious backward radiation and uncontrollable ablation range caused by impedance mismatch caused by tissue change (complex dielectric constant, attenuation constant, electric conductivity, thermal conductivity, specific heat capacity and tissue strength) in the ablation process are overcome.
Therefore, in order to overcome the technical problems, and reduce a series of effects caused by tissue change in the microwave ablation process, the embodiment provides an ultra-wideband continuous variable frequency microwave ablation system so as to improve the degree of freedom of ablation regulation and control and overcome the problems of impedance mismatch and the like caused by tissue change.
Next, a detailed description of an ultra-wideband continuous variable frequency microwave ablation system provided in the implementation of the present application, and referring to fig. 1, the system may include:
a microwave source, a directional coupler, a microwave ablation antenna, a power meter system, and a computer;
the directional coupler is respectively connected with the microwave source, the microwave ablation antenna and the power meter system; the computer is respectively connected with the microwave source and the power meter system;
the microwave source is used for generating microwave energy;
the directional coupler is used for transmitting the microwave energy to the microwave ablation antenna;
the microwave ablation antenna is used for carrying out electromagnetic radiation by utilizing the microwave energy;
the power meter system is used for measuring the microwave energy; transmitting the measurement results to the computer;
the computer is used for determining the impedance matching degree of the microwave ablation antenna according to the measurement result; when the impedance matching degree is lower than a preset threshold value, control signals of different frequency bands are sequentially sent to the microwave source so as to improve the impedance matching degree; when the impedance matching degree reaches a preset target value, the frequency band of the control signal is maintained at the current frequency band, and the control signal of the current frequency band is continuously sent to the microwave source.
Further, the microwave source comprises a signal generator and a power amplifier; the signal generator is connected with the power amplifier;
wherein the computer is connected with the signal generator, and the power amplifier is connected with the directional coupler;
the signal generator is used for generating a microwave signal;
the power amplifier is used for amplifying the microwave signal to obtain the microwave energy.
The broadband of the microwave source of the embodiment is realized by combining a high-power broadband amplifier with a signal generator, so that the broadband high-power microwave source can be realized at low cost.
Still further, the microwave ablation system further comprises an analog-to-digital conversion device;
one end of the analog-to-digital conversion device is connected with the power meter system, and the other end of the analog-to-digital conversion device is connected with the computer;
the analog-to-digital conversion device is used for converting the measurement result of the analog signal into a digital signal and then transmitting the digital signal to the computer.
As a further embodiment, the directional coupler includes a first port, a second port, a third port, and a fourth port;
the power meter system comprises a first power meter and a second power meter;
wherein the power amplifier is connected with the directional coupler through the first port; the microwave ablation antenna is connected with the directional coupler through the second port;
the first power meter is connected with the directional coupler through the third port, and the second power meter is connected with the directional coupler through the fourth port;
the first power meter is used for measuring the microwave energy in and out of the microwave ablation antenna;
the second power meter is used for measuring the microwave energy in and out of the power amplifier.
Optionally, the whole structure of the microwave ablation antenna is needle-shaped;
the microwave ablation antenna sequentially comprises a top metal layer, an upper dielectric layer, a solidified layer, an inner metal layer, a bottom dielectric layer and a bottom metal layer from top to bottom;
the tail part of the microwave ablation antenna is a feed end, and the feed end is connected with the directional coupler; the head of the microwave ablation antenna is needle-shaped;
the tail parts of the top metal layer, the upper medium layer, the solidified layer, the inner metal layer, the bottom medium layer and the bottom metal layer are wider than the diameter of the needle-shaped microwave ablation antenna.
Further, the outer wall of the needle body of the microwave ablation antenna is provided with a plurality of circles of annular grooves;
the annular grooves are arranged below the head of the microwave ablation antenna;
the metal width of the inner metal layer at the annular groove position is wider than that of the inner metal layer at other positions.
In order to facilitate a clearer understanding of the present application, the present application will be described below in terms of one complete alternative example.
Specifically, the embodiment provides an ultra-wideband continuous variable frequency microwave ablation system which can reduce the efficiency reduction of an ablation process even caused by impedance mismatch problems caused by immune tissue changes, the reduction of an ablation range and uncontrollable ablation shapes. The system is in the form of a complete automatic control microwave ablation system. Fig. 2 is a schematic structural diagram of a microwave ablation system according to the present embodiment, which may include five parts: the first part is a microwave source, the composition of which is shown in figure 3. The second essential part is a directional coupler, the composition of which is shown in fig. 4, the microwave source and the directional coupler being connected by a transmission line. The third part is a microwave ablation antenna into which microwave energy is coupled through a directional coupler, a schematic of which is shown in fig. 5. The fourth part is a power meter connected to the directional coupler via a transmission line, the schematic diagram of which is shown in fig. 6. The fifth part is a computer, the computer is connected with the power meter through the analog-digital conversion device by a signal wire, and the basic control principle is shown in figure 7. A schematic diagram of a local scenario of tumor treatment using the microwave ablation system of the present embodiment is shown in fig. 8.
First, a description will be given of a microwave ablation antenna shown in fig. 5: the whole structure of the microwave ablation antenna is needle-shaped, so that the microwave ablation antenna can be called a microwave ablation needle. The antenna consists of a six-layer structure, and comprises a top metal layer, an upper dielectric layer, a solidified layer (used for adhesion between layers), an inner metal layer, a bottom dielectric layer and a bottom metal layer from top to bottom in sequence. The tail design of the microwave ablation antenna is shown in the lower left part of fig. 5, the wider part is the feeding part of the microwave ablation antenna, and the coplanar waveguide is adopted to convert the strip line form to feed the ablation antenna with high efficiency. The bottom right part of fig. 5 is designed for the top of the microwave ablation antenna, the sharp structure provides a guarantee for invading the tissue to be treated, in addition, six circles of annular grooves are etched at the position close to the top, effective electromagnetic radiation is guaranteed, and in addition, widening treatment is carried out at the metal part inside the annular grooves, so that the effective working bandwidth of the ablation antenna is greatly expanded, and the requirement of broadband continuous microwave ablation is met.
The microwave ablation system of the embodiment can be divided into two processes of microwave ablation and automatic control when in operation, and the microwave ablation process can comprise: microwave energy generated by a microwave source is transmitted to a directional coupler through a transmission line and then enters a microwave ablation antenna to be inserted into tumor tissues for ablation treatment, wherein the microwave source, the coupler and the microwave ablation antenna are all of a broadband design; the automated control process may include: the computer obtains the real-time power transmission condition of the microwave ablation antenna through the power meter, and then the computer utilizes the instruction to carry out real-time sweep frequency regulation and control on the microwave source, so that the requirement of impedance matching is met at any moment in the ablation process.
Next, the microwave ablation system of the present embodiment will be described with reference to fig. 2.
In particular, a microwave source is a source of all energy, including a signal generator and a power amplifier, for amplifying small signals to achieve a higher power output.
The microwave energy of the microwave source is transmitted into the directional coupler, and the directional coupler is a four-port device, wherein one port is connected with the microwave source; one port is connected with a microwave ablation needle (antenna), wherein the microwave ablation needle is the microwave ablation antenna; the other two ports are respectively connected with two power meters to observe the microwave energy of each port. The right power meter is used for observing the energy amount of the microwave source entering and exiting, and the left power meter is used for observing the energy amount of the ablation antenna entering and exiting.
The power meter on the left side converts an analog signal into a digital signal through the digital-to-analog conversion device and then transmits the digital signal into a computer, the digital signal at the moment contains energy information on the microwave ablation antenna, the energy in-out relation of the information reflects the current impedance matching level of the microwave ablation antenna, a corresponding mapping relation is established between the digital signal and the analog signal, the impedance matching degree of the current microwave ablation antenna can be known in real time, and the impedance matching degree determines whether microwave energy can be fed into the ablation antenna efficiently, so that effective ablation is realized.
When the impedance matching degree of the microwave ablation antenna is poor, the computer can sweep the frequency signal of the signal generator to make the signal generator send signals of different frequency bands to the microwave ablation antenna when the energy feed-in efficiency is low, and after the signal of a certain frequency band enters the ablation antenna, the impedance matching of the signal is improved, and after the microwave energy is fed in efficiently, the sweep frequency is stopped and the signal of the frequency band is continuously output, so that the efficient ablation effect is obtained.
The microwave ablation antenna is directly inserted into the organ to be treated, and the appearance of the microwave ablation antenna is needle-shaped, so the microwave ablation antenna is called as a microwave ablation needle. But in fact is also an antenna, which ablates the tumor portion in the organ to be treated, leaving a good portion.
An example of a specific microwave ablation system design with an operating frequency band of 0.5-6 GHz is given below.
Specifically, the ultra-wideband continuous variable frequency microwave ablation system irrelevant to medium change comprises a wideband high-power microwave source composed of a signal generator and a wideband 100W high-power amplifier working in the frequency range of 0.5-6 GHz; a broadband directional coupler; a broadband microwave ablation antenna manufactured by a multilayer PCB process in a working frequency range of 0.4-6 GHz; a broadband power meter; analog-to-digital converting the signal; and a computer automation control system for testing the liver of the isolated animal to be tested.
Under the working condition of a broadband, the microwave ablation antenna can always work at a frequency point meeting the impedance matching requirement by utilizing a set of closed-loop system and assisting with automatic control and judging instructions, and further the problem of impedance mismatch caused by tissue medium characteristic change in the ablation process at a single frequency point or a plurality of frequency points is solved.
The above design example can refer to the microwave ablation system shown in fig. 2, wherein the microwave source consists of a signal generator and a broadband high-power amplifier, and the broadband high-power microwave source is skillfully replaced. The power transmission condition of the ablation antenna is monitored in real time through the analog-to-digital conversion of the directional coupler, and the real-time frequency adjustment is realized by assisting with the judgment instruction.
The embodiment of the application provides a control method of an ultra-wideband continuous variable frequency microwave ablation system, which is applied to a computer in the ultra-wideband continuous variable frequency microwave ablation system, and comprises the following steps:
obtaining a measurement result of the microwave energy;
determining the impedance matching degree of the microwave ablation antenna according to the measurement result;
when the impedance matching degree is lower than a preset threshold value, control signals of different frequency bands are sequentially sent to a microwave source so as to improve the impedance matching degree;
when the impedance matching degree reaches a preset target value, the frequency band of the control signal is maintained at the current frequency band, and the control signal of the current frequency band is continuously sent to the microwave source.
Specifically, the power meter is connected with the digital-to-analog conversion device, and the analog signal read by the power meter contains impedance matching information of the microwave ablation antenna, namely, information of feeding microwave energy into the microwave ablation antenna. The analog signals are converted into digital signals and then enter a computer, a one-to-one correspondence relation between the impedance matching degree in the analog signals and the digital signals can be established through mapping of preset rules, corresponding threshold judgment instructions are correspondingly set according to the change of the digital signals, when the impedance of an ablation antenna is not matched, the computer controls a signal generator to sweep, when the impedance of the ablation antenna is swept to a certain frequency band/frequency point, signals returned from a power meter reflect microwave ablation antenna impedance matching to be improved, and when the matching degree is met, the computer sends instructions to the signal generator to stop sweeping and continuously send current frequency signals. The embodiment forms a set of full-closed-loop automatic sweep frequency system, ensures that the ablation antenna can work in a state with good impedance matching in real time, ensures high-efficiency energy output and realizes high-efficiency and rapid ablation effect.
Further, the determining the impedance matching degree of the microwave ablation antenna according to the measurement result includes:
determining an analog signal corresponding to the measurement result of the digital signal according to a preset mapping relation;
and determining the impedance matching degree of the microwave ablation antenna according to the analog signal.
The embodiment of the application has the following beneficial effects:
1) The broadband design of the microwave ablation system overcomes the negative effects of impedance mismatch and the like caused by the medium parameters which change in real time in the microwave ablation process.
2) The wideband design of the microwave source is composed of a signal generator and a wideband high-power amplifier, so that the wideband high-power microwave source can be realized at low cost.
3) The microwave ablation antenna adopts a broadband design.
4) And the full-automatic real-time self-adaptive frequency regulation and control is realized by computer assistance.
5) The microwave ablation system is reasonable in design, for example, a directional coupler is used for connecting a computer, and power transmission of the microwave ablation antenna is realized through an analog-to-digital conversion device.
The embodiment of the application also provides electronic equipment, which comprises a memory and a processor, wherein the memory stores a computer program, and the processor realizes the control method when executing the computer program.
Specifically, the electronic device may be a user terminal or a server.
The embodiment of the application also provides a computer readable storage medium, wherein the computer readable storage medium stores a computer program, and the computer program realizes the control method when being executed by a processor.
The memory, as a non-transitory computer readable storage medium, may be used to store non-transitory software programs as well as non-transitory computer executable programs. In addition, the memory may include high-speed random access memory, and may also include non-transitory memory, such as at least one magnetic disk storage device, flash memory device, or other non-transitory solid state storage device. In some embodiments, the memory optionally includes memory remotely located relative to the processor, the remote memory being connectable to the processor through a network. Examples of such networks include, but are not limited to, the internet, intranets, local area networks, mobile communication networks, and combinations thereof.
The present application also discloses a computer program product or a computer program comprising computer instructions stored in a computer readable storage medium. The computer instructions may be read from a computer-readable storage medium by a processor of an electronic device, which executes the computer instructions, causing the electronic device to perform the aforementioned control method.
In some alternative embodiments, the functions/acts noted in the block diagrams may occur out of the order noted in the operational illustrations. For example, two blocks shown in succession may in fact be executed substantially concurrently or the blocks may sometimes be executed in the reverse order, depending upon the functionality/acts involved. Furthermore, the embodiments presented and described in the flowcharts of this application are provided by way of example in order to provide a more thorough understanding of the technology. The disclosed methods are not limited to the operations and logic flows presented herein. Alternative embodiments are contemplated in which the order of various operations is changed, and in which sub-operations described as part of a larger operation are performed independently.
Furthermore, while the present application is described in the context of functional modules, it should be appreciated that, unless otherwise indicated, one or more of the described functions and/or features may be integrated in a single physical device and/or software module or one or more functions and/or features may be implemented in separate physical devices or software modules. It will also be appreciated that a detailed discussion of the actual implementation of each module is not necessary to an understanding of the present application. Rather, the actual implementation of the various functional modules in the apparatus disclosed herein will be apparent to those skilled in the art from consideration of their attributes, functions and internal relationships. Thus, those of ordinary skill in the art will be able to implement the present application as set forth in the claims without undue experimentation. It is also to be understood that the specific concepts disclosed are merely illustrative and are not intended to be limiting upon the scope of the application, which is to be defined by the appended claims and their full scope of equivalents.
The functions, if implemented in the form of software functional units and sold or used as a stand-alone product, may be stored in a computer-readable storage medium. Based on such understanding, the technical solution of the present application may be embodied essentially or in a part contributing to the prior art or in a part of the technical solution, in the form of a software product stored in a storage medium, comprising several instructions for causing an electronic device (which may be a personal computer, a server, or a network device, etc.) to perform all or part of the steps of the method described in the embodiments of the present application. And the aforementioned storage medium includes: a U-disk, a removable hard disk, a Read-Only Memory (ROM), a random access Memory (RAM, random Access Memory), a magnetic disk, or an optical disk, or other various media capable of storing program codes.
Logic and/or steps represented in the flowcharts or otherwise described herein, e.g., a ordered listing of executable instructions for implementing logical functions, can be embodied in any computer-readable medium for use by or in connection with an instruction execution system, apparatus, or device, such as a computer-based system, processor-containing system, or other system that can fetch the instructions from the instruction execution system, apparatus, or device and execute the instructions. For the purposes of this description, a "computer-readable medium" can be any means that can contain, store, communicate, propagate, or transport the program for use by or in connection with the instruction execution system, apparatus, or device.
More specific examples (a non-exhaustive list) of the computer-readable medium would include the following: an electrical connection (electronic device) having one or more wires, a portable computer diskette (magnetic device), a Random Access Memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), an optical fiber device, and a portable compact disc read-only memory (CDROM). In addition, the computer readable medium may even be paper or other suitable medium on which the program is printed, as the program may be electronically captured, via, for instance, optical scanning of the paper or other medium, then compiled, interpreted or otherwise processed in a suitable manner, if necessary, and then stored in a computer memory.
It is to be understood that portions of the present application may be implemented in hardware, software, firmware, or a combination thereof. In the above-described embodiments, the various steps or methods may be implemented in software or firmware stored in a memory and executed by a suitable instruction execution system. For example, if implemented in hardware, as in another embodiment, may be implemented using any one or combination of the following techniques, as is well known in the art: discrete logic circuits having logic gates for implementing logic functions on data signals, application specific integrated circuits having suitable combinational logic gates, programmable Gate Arrays (PGAs), field Programmable Gate Arrays (FPGAs), and the like.
In the description of the present specification, a description referring to terms "one embodiment," "some embodiments," "examples," "specific examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present application. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiments or examples. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
While embodiments of the present application have been shown and described, it will be understood by those of ordinary skill in the art that: many changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the application, the scope of which is defined by the claims and their equivalents.
While the preferred embodiment of the present invention has been described in detail, the present invention is not limited to the embodiment, and those skilled in the art can make various equivalent modifications or substitutions without departing from the spirit of the present invention, and the equivalent modifications or substitutions are included in the scope of the present invention as defined in the appended claims.

Claims (10)

1. An ultra-wideband continuous variable frequency microwave ablation system, comprising: a microwave source, a directional coupler, a microwave ablation antenna, a power meter system, and a computer;
the directional coupler is respectively connected with the microwave source, the microwave ablation antenna and the power meter system; the computer is respectively connected with the microwave source and the power meter system;
the microwave source is used for generating microwave energy;
the directional coupler is used for transmitting the microwave energy to the microwave ablation antenna;
the microwave ablation antenna is used for carrying out electromagnetic radiation by utilizing the microwave energy;
the power meter system is used for measuring the microwave energy; transmitting the measurement results to the computer;
the computer is used for determining the impedance matching degree of the microwave ablation antenna according to the measurement result; when the impedance matching degree is lower than a preset threshold value, control signals of different frequency bands are sequentially sent to the microwave source so as to improve the impedance matching degree; when the impedance matching degree reaches a preset target value, the frequency band of the control signal is maintained at the current frequency band, and the control signal of the current frequency band is continuously sent to the microwave source.
2. The ultra-wideband continuous variable frequency microwave ablation system according to claim 1, wherein the microwave source comprises a signal generator and a power amplifier; the signal generator is connected with the power amplifier;
wherein the computer is connected with the signal generator, and the power amplifier is connected with the directional coupler;
the signal generator is used for generating a microwave signal;
the power amplifier is used for amplifying the microwave signal to obtain the microwave energy.
3. The ultra-wideband continuous variable frequency microwave ablation system according to claim 2, wherein the microwave ablation system further comprises an analog-to-digital conversion device;
one end of the analog-to-digital conversion device is connected with the power meter system, and the other end of the analog-to-digital conversion device is connected with the computer;
the analog-to-digital conversion device is used for converting the measurement result of the analog signal into a digital signal and then transmitting the digital signal to the computer.
4. The ultra-wideband continuous variable frequency microwave ablation system according to claim 3, wherein the directional coupler comprises a first port, a second port, a third port, and a fourth port;
the power meter system comprises a first power meter and a second power meter;
wherein the power amplifier is connected with the directional coupler through the first port; the microwave ablation antenna is connected with the directional coupler through the second port;
the first power meter is connected with the directional coupler through the third port, and the second power meter is connected with the directional coupler through the fourth port;
the first power meter is used for measuring the microwave energy in and out of the microwave ablation antenna;
the second power meter is used for measuring the microwave energy in and out of the power amplifier.
5. The ultra-wideband continuous variable frequency microwave ablation system according to claim 1, wherein the microwave ablation antenna has a needle-like overall structure;
the microwave ablation antenna sequentially comprises a top metal layer, an upper dielectric layer, a solidified layer, an inner metal layer, a bottom dielectric layer and a bottom metal layer from top to bottom;
the tail part of the microwave ablation antenna is a feed end, and the feed end is connected with the directional coupler; the head of the microwave ablation antenna is needle-shaped;
the tail parts of the top metal layer, the upper medium layer, the solidified layer, the inner metal layer, the bottom medium layer and the bottom metal layer are wider than the diameter of the needle-shaped microwave ablation antenna.
6. The ultra-wideband continuous variable frequency microwave ablation system according to claim 5, wherein the outer wall of the needle body of the microwave ablation antenna is provided with a plurality of annular grooves;
the annular grooves are arranged below the head of the microwave ablation antenna;
the metal width of the inner metal layer at the annular groove position is wider than that of the inner metal layer at other positions.
7. A method for controlling an ultra-wideband continuous variable frequency microwave ablation system, applied to a computer in an ultra-wideband continuous variable frequency microwave ablation system according to any one of claims 1 to 6, the method comprising:
obtaining a measurement result of the microwave energy;
determining the impedance matching degree of the microwave ablation antenna according to the measurement result;
when the impedance matching degree is lower than a preset threshold value, control signals of different frequency bands are sequentially sent to a microwave source so as to improve the impedance matching degree;
when the impedance matching degree reaches a preset target value, the frequency band of the control signal is maintained at the current frequency band, and the control signal of the current frequency band is continuously sent to the microwave source.
8. The method for controlling an ultra-wideband continuously variable frequency microwave ablation system according to claim 7, wherein determining the impedance matching of the microwave ablation antenna according to the measurement result comprises:
determining an analog signal corresponding to the measurement result of the digital signal according to a preset mapping relation;
and determining the impedance matching degree of the microwave ablation antenna according to the analog signal.
9. An electronic device comprising a processor and a memory;
the memory is used for storing programs;
the processor executing the program implements the method of claim 7 or 8.
10. A computer-readable storage medium, characterized in that the storage medium stores a program, which is executed by a processor to implement the method of claim 7 or 8.
CN202311714213.6A 2023-12-13 2023-12-13 Ultra-wideband continuous variable frequency microwave ablation system and control method thereof Pending CN117653325A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118092294A (en) * 2024-04-29 2024-05-28 海能未来技术集团股份有限公司 Intelligent control system of microwave digestion instrument

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118092294A (en) * 2024-04-29 2024-05-28 海能未来技术集团股份有限公司 Intelligent control system of microwave digestion instrument

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