CN117481616B - Injection and extraction device and method based on photoacoustic three-dimensional imaging - Google Patents
Injection and extraction device and method based on photoacoustic three-dimensional imaging Download PDFInfo
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- CN117481616B CN117481616B CN202311844997.4A CN202311844997A CN117481616B CN 117481616 B CN117481616 B CN 117481616B CN 202311844997 A CN202311844997 A CN 202311844997A CN 117481616 B CN117481616 B CN 117481616B
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- 238000002347 injection Methods 0.000 title claims abstract description 38
- 239000007924 injection Substances 0.000 title claims abstract description 38
- 238000003384 imaging method Methods 0.000 title claims abstract description 36
- 238000000605 extraction Methods 0.000 title claims abstract description 30
- 238000000034 method Methods 0.000 title abstract description 8
- 239000000523 sample Substances 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 23
- 229920003023 plastic Polymers 0.000 claims description 22
- 239000004033 plastic Substances 0.000 claims description 20
- 239000012780 transparent material Substances 0.000 claims description 3
- 230000031700 light absorption Effects 0.000 abstract description 7
- 239000013076 target substance Substances 0.000 abstract description 4
- 230000002792 vascular Effects 0.000 abstract description 4
- 230000000007 visual effect Effects 0.000 abstract description 4
- 238000010521 absorption reaction Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 230000005484 gravity Effects 0.000 description 3
- 230000002439 hemostatic effect Effects 0.000 description 3
- 238000005498 polishing Methods 0.000 description 3
- 238000007781 pre-processing Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000001052 transient effect Effects 0.000 description 3
- 244000043261 Hevea brasiliensis Species 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 229920003052 natural elastomer Polymers 0.000 description 2
- 229920001194 natural rubber Polymers 0.000 description 2
- 239000013307 optical fiber Substances 0.000 description 2
- 239000002985 plastic film Substances 0.000 description 2
- 229920002635 polyurethane Polymers 0.000 description 2
- 239000004814 polyurethane Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 238000012634 optical imaging Methods 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
- A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
- A61M5/427—Locating point where body is to be pierced, e.g. vein location means using ultrasonic waves, injection site templates
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Vascular Medicine (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Acoustics & Sound (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Abstract
The invention discloses an injection and extraction device and method based on photoacoustic three-dimensional imaging, wherein the device comprises: the cambered surface array ultrasonic probe comprises a rigid hemisphere, a transducer array element and a laser emitting piece, wherein the transducer array element and the laser emitting piece are connected with the rigid hemisphere; a chute is arranged on the rigid hemisphere, and a hole site plate is arranged in the chute; the hole site plate is provided with an opening; the flexible transparent water-holding structure comprises a flexible transparent film which is matched with the rigid hemispheroids, one end of the flexible transparent film is communicated with the flexible transparent film, and the other end of the flexible transparent film is connected with the accommodating channel of the hole site board. The invention realizes an injection or extraction device based on three-dimensional photoacoustic imaging, can observe and see the distribution condition of vascular networks under biological tissues or imitation bodies or other target substance components with special light absorption in real time, and helps operators to complete injection or extraction operation better; by photoacoustic three-dimensional imaging, a photoacoustic image of biological tissue or the inside of an ex-vivo object, invisible to the human eye, can be provided, pushing the needle into place under visual conditions.
Description
Technical Field
The invention relates to the field of medicines, in particular to an injection and extraction device and method based on photoacoustic three-dimensional imaging.
Background
At present, in the working of medicine injection, blood drawing, biomedical experiments and the like, the injection is basically completed through an injector, however, when the simple injector is used for drawing or injecting, the injection or drawing efficiency is determined according to the operational experience;
if the target can be accurately seen in real time, the operator can be helped to operate better and safer;
the photoacoustic imaging is a novel biomedical imaging mode, bypasses the problem that an optical signal cannot be transmitted from deep tissues, transmits the signal from the deep tissues by utilizing sound waves, and combines the characteristics of high optical imaging spatial resolution and deep acoustic imaging penetration depth.
When we irradiate tissue with a short pulse laser, the tissue absorbs the energy and undergoes a rapid thermal relaxation expansion to produce an ultrasonic wave, called a photoacoustic signal, which contains the absorption profile of the tissue;
the photoacoustic signals are received by using the photoacoustic probe and then reconstructed, so that the required tissue information can be obtained;
therefore, how to combine the injector with the photoacoustic imaging and use it in the work of drug injection, blood drawing, biomedical experiments, etc. is a problem that needs to be solved at present.
Disclosure of Invention
The invention aims to: an injection and extraction device and method based on photoacoustic three-dimensional imaging are provided to solve the above problems in the prior art.
The technical scheme is as follows: an injection and extraction device based on photoacoustic three-dimensional imaging, comprising:
the cambered surface array ultrasonic probe comprises a rigid hemisphere, and a transducer array element and a laser emitting part which are connected with the rigid hemisphere;
A chute is formed in the rigid hemisphere, and a hole site plate is arranged in the chute; the hole site plate is in sliding connection with the chute;
The hole site plate is provided with an opening;
The aperture is used to provide physical access to the site injector or extractor;
the flexible transparent water-holding structure comprises a flexible transparent film which is matched with the rigid hemispheroids, and a containing channel, one end of which is communicated with the flexible transparent film, and the other end of which is connected with the hole site board;
the syringe is placed through the opening in the receiving channel.
The invention realizes an injection or extraction device based on three-dimensional photoacoustic imaging, can observe and see the distribution condition of vascular networks under biological tissues or imitation bodies or other target substance components with special light absorption in real time, and helps operators to complete injection or extraction operation better;
By photoacoustic three-dimensional imaging, a photoacoustic image of biological tissue or the inside of an ex-vivo object, invisible to the human eye, can be provided, pushing the needle into place under visual conditions.
A spatial positional relationship between the needle and the tissue can be observed;
the direction can be found left and right by rotating the hemispheroids, and the angle adjustment of the needle head can be realized by moving the movable hole site plate up and down;
the device can adapt to different injection or extraction tools by changing different transparent water-holding structures;
Realizing three-dimensional photoacoustic imaging by using the three-dimensional hemispherical ultrasonic transducer array as a navigation basis of the needle head;
a detachable transparent water-holding structure;
The movable hole site board is connected with the transparent water pocket structure together, and a mode of adjusting the angle of the needle head is provided.
In a further embodiment, the receiving channel comprises a flexible channel tube connected at the center of the flexible transparent film, and a plastic channel tube with one end connected with the flexible channel tube and the other end connected with the hole site plate;
the syringe is disposed within the plastic channel tube.
In a further embodiment, the opening is provided with connecting threads;
the plastic channel pipe is provided with a fixed thread matched with the connecting thread at one end far away from the flexible channel pipe and is used for fixedly connecting the plastic channel pipe to a movable hole site plate on the rigid hemisphere.
In a further embodiment, the ultrasonic transducer array elements are designed into a plurality of groups and are uniformly distributed on the rigid hemispheroids;
The laser emitting part is at least designed singly, the laser emitting direction is the center of a rigid hemisphere or the periphery of the center of the rigid hemisphere, and lights are emitted to the imaging target part;
Preferably, at least one of the laser shots is selected;
at least 100 ultrasonic transducer array elements are selected.
In a further embodiment, the laser emitter circumscribes a laser source.
The laser source comprises a nanosecond pulse generator connected with the laser emitting part, and the pulse generator can emit nanosecond pulse laser and is connected with the laser emitting part through a space light path or an optical fiber bundle.
In a further embodiment, the rigid hemispheroids are provided with water injection holes through which water can be injected.
In a further embodiment, the flexible transparent film is made of a flexible transparent material;
materials such as transparent plastic film, natural rubber, polyurethane, etc.;
The plastic channel pipe and the flexible channel pipe penetrate through the flexible transparent film;
the flexible channel tube material can be consistent with the flexible transparent film.
In a further embodiment, the cambered surface array ultrasonic probe is externally connected with a photoacoustic host system;
the photoacoustic host system comprises a computer, a display and a data acquisition module;
The signal interface on the data acquisition module is connected to each transducer array element, the analog signals are acquired and converted into digital signals, and finally the digital signals are transmitted to a computer for reconstruction calculation, and the display displays images.
In a further embodiment, the rigid hemisphere houses a video image module;
The video image module comprises a miniature camera connected with the display, is built-in on the rigid hemisphere, is used for collecting image information in the rigid hemisphere, and is displayed to a user through the display, and the user can see the needle condition in the rigid hemisphere through the module.
An injection and extraction method based on photoacoustic three-dimensional imaging comprises the following steps:
Step 1, when in use, a plastic channel pipe is screwed on a hole on a movable hole site plate, then a flexible transparent film is unfolded and pressed on the lower edge of a rigid hemisphere, and a water containing cavity is formed between a flexible transparent water pocket structure and the rigid hemisphere;
step 2, filling water into the rigid hemisphere through the water filling hole, wherein the flexible transparent film protrudes downwards due to the gravity and pressure of the water;
Step 3, buckling the rigid hemispheroids on the target positions, placing the sphere center positions of the rigid hemispheroids on the positions to be injected or extracted, and observing the specific positions of the syringe needles through the video image module;
Step 4, starting a laser source and a photoacoustic host system, and starting polishing, collecting and reconstructing imaging; at the moment, the laser emitting part reflects pulse laser to irradiate the sphere center part of the rigid hemisphere, the laser irradiates the target area through the flexible transparent film, enters the inside of the target through scattering, and causes transient light absorption and thermal expansion due to the absorption of scattered laser energy by substances in the inside of the target to generate ultrasonic waves, the transducer array element on the rigid hemisphere receives ultrasonic signals and inputs the ultrasonic signals to the photoacoustic host system, and the photoacoustic host system displays three-dimensional photoacoustic images on a display screen after analog-digital conversion, data preprocessing, image reconstruction, image processing and display;
step 5, inserting an injector or an extractor into the hole of the hole site plate on the rigid hemisphere through the plastic channel pipe, putting the needle head down from the flexible channel pipe, observing the video image inside the rigid hemisphere acquired by the video image module from the display, observing the position of the needle head, and observing the position relation between the needle head and the target tissue through the three-dimensional photoacoustic image;
Step 6, after the three-dimensional photoacoustic image observes the relative positions of the target and the needle, the angle of the needle can be adjusted by sliding a hole site plate on the rigid hemisphere, the whole rigid hemisphere is rotated, after the proper angle is found, the needle is pushed to insert the needle into the target tissue, the position condition of the needle in the target tissue is seen in real time through the three-dimensional photoacoustic image, and after the proper position is reached, injection or extraction operation is carried out;
and 7, after the step is finished, the needle is withdrawn, the rigid hemisphere is separated from the target position, and the target position is sterilized and hemostatic.
The beneficial effects are that: the invention discloses an injection and extraction device and a method based on photoacoustic three-dimensional imaging, wherein the invention designs an arc array ultrasonic probe and a flexible transparent water-pocket structure to realize the injection or extraction device based on three-dimensional photoacoustic imaging, so that the distribution condition of vascular networks under biological tissues or imitation bodies or other target substance components with special light absorption can be observed in real time, and operators can be helped to complete injection or extraction operation better;
By photoacoustic three-dimensional imaging, a photoacoustic image of biological tissue or the inside of an ex-vivo object, invisible to the human eye, can be provided, pushing the needle into place under visual conditions.
Drawings
Fig. 1 is a schematic structural view of the present invention.
FIG. 2 is a schematic view of the structure of the flexible transparent water bag.
The reference numerals are:
1. A syringe; 2. a receiving channel; 21. a plastic channel tube; 22. a flexible channel tube; 3. a hole site plate; 4. rigid hemispheres; 5. a transducer array element; 6. a laser emitting member; 7. a flexible transparent film.
Detailed Description
The present application relates to an injection and extraction device and method based on photoacoustic three-dimensional imaging, and is explained in detail below through specific embodiments.
An injection and extraction device and method based on photoacoustic three-dimensional imaging, comprising:
The cambered surface array ultrasonic probe comprises a rigid hemisphere 4, a transducer array element 5 and a laser emitting piece 6, wherein the transducer array element 5 and the laser emitting piece 6 are connected with the rigid hemisphere 4;
A chute is formed in the rigid hemispheroid 4, and a hole site plate 3 is arranged in the chute; the hole site plate 3 is in sliding connection with the chute;
the hole site plate 3 is provided with an opening;
the aperture is used to provide physical access to the site injector 1 or the extractor;
the flexible transparent water-holding structure comprises a flexible transparent film 7 matched with the rigid hemispheroids 4 and a containing channel 2, one end of which is communicated with the flexible transparent film 7, and the other end of which is connected with the hole site plate 3;
the syringe 1 is placed through the opening in the receiving channel 2.
The invention realizes an injection or extraction device based on three-dimensional photoacoustic imaging, can observe and see the distribution condition of vascular networks under biological tissues or imitation bodies or other target substance components with special light absorption in real time, and helps operators to complete injection or extraction operation better;
By photoacoustic three-dimensional imaging, a photoacoustic image of biological tissue or the inside of an ex-vivo object, invisible to the human eye, can be provided, pushing the needle into place under visual conditions.
A spatial positional relationship between the needle and the tissue can be observed;
The direction can be found left and right by rotating the hemispheroids, and the angle adjustment of the needle head can be realized by moving the movable hole site plate 3 up and down;
the device can adapt to different injection or extraction tools by changing different transparent water-holding structures;
Realizing three-dimensional photoacoustic imaging by using the three-dimensional hemispherical ultrasonic transducer array as a navigation basis of the needle head;
a detachable transparent water-holding structure;
The movable hole site plate 3 is connected with the transparent water pocket structure to provide a mode of adjusting the angle of the pinhead.
The accommodating channel 2 comprises a flexible channel tube 22 connected to the center of the flexible transparent film 7, and a plastic channel tube 21 with one end connected to the flexible channel tube 22 and the other end connected to the hole site plate 3;
the syringe 1 is disposed within the plastic tunnel tube 21.
The connecting threads are arranged on the open holes;
the end of the plastic channel tube 21 remote from the flexible channel tube 22 is provided with a fixing thread adapted to the connecting thread for fixedly connecting the plastic channel tube 21 to the movable hole site plate 3 on the rigid hemisphere 4.
The ultrasonic transducer array elements 5 are designed into a plurality of groups and are uniformly distributed on the rigid hemispheroids 4;
the laser emitting part 6 is at least designed singly, the laser emitting direction is the center of the rigid hemisphere 4 or the periphery of the center of the rigid hemisphere 4, and lights the imaging target part;
Preferably, at least one of the laser shots is selected;
at least 100 ultrasonic transducer array elements 5 are selected.
The laser emitting part 6 is externally connected with a laser source.
The laser source comprises a nanosecond pulse generator connected to the laser emitting member 6, which pulse generator can emit nanosecond pulse laser light and is connected to the laser emitting member 6 by a spatial light path or an optical fiber or a fiber bundle.
The rigid hemispheroids 4 are provided with water injection holes through which water can be injected into the inner side.
The flexible transparent film 7 is made of a flexible transparent material;
materials such as transparent plastic film, natural rubber, polyurethane, etc.;
A plastic channel tube 21 and a flexible channel tube 22 penetrate the flexible transparent film 7;
the flexible channel tube 22 may be made of the same material as the flexible transparent film 7.
The cambered surface array ultrasonic probe is externally connected with a photoacoustic host system;
the photoacoustic host system comprises a computer, a display and a data acquisition module;
the signal interface on the data acquisition module is connected to each transducer array element 5, acquires and converts the analog signals into digital signals, and finally transmits the digital signals to a computer for reconstruction calculation, and the display displays images.
The rigid hemispheroids 4 are internally provided with video image modules;
The video image module comprises a miniature camera connected with a display, is built-in on the rigid hemisphere 4 and is used for collecting image information in the rigid hemisphere 4, and is displayed to a user through the display, and the user can see the needle condition in the rigid hemisphere 4 through the module.
An injection and extraction method based on photoacoustic three-dimensional imaging comprises the following steps:
Step 1, when in use, the plastic channel pipe 21 is screwed on the hole on the movable hole site plate 3, then the flexible transparent film 7 is unfolded and pressed on the lower edge of the rigid hemisphere 4, and a water containing cavity is formed between the flexible transparent water containing structure and the rigid hemisphere 4;
step 2, filling water into the rigid hemispheroids 4 through the water filling holes, wherein the flexible transparent films 7 protrude downwards due to the gravity and the pressure of the water;
Step 3, buckling the rigid hemispheroids 4 on a target position, placing the sphere center of the rigid hemispheroids 4 at a position to be injected or extracted, and observing the specific position of the needle head of the injector 1 through a video image module;
Step 4, starting a laser source and a photoacoustic host system, and starting polishing, collecting and reconstructing imaging; at this time, the laser emitting part 6 reflects pulse laser to irradiate the sphere center part of the rigid hemisphere 4, the laser irradiates the target area through the flexible transparent film 7, enters the inside of the target through scattering, and causes transient light absorption and thermal expansion due to the absorption of scattered laser energy by substances in the inside of the target to generate ultrasonic waves, the transducer array element 5 on the rigid hemisphere 4 receives ultrasonic signals and inputs the ultrasonic signals into the photoacoustic host system, and the photoacoustic host system displays a three-dimensional photoacoustic image on a display screen after analog-digital conversion, data preprocessing, image reconstruction, image processing and display;
Step 5, inserting the injector 1 or the extractor through the plastic channel tube 21 from the opening of the hole site plate 3 on the rigid hemisphere 4, putting the needle head down from the flexible channel tube 22, observing the video image inside the rigid hemisphere 4 acquired by the video image module from the display, observing the position of the needle head, and observing the position relationship between the needle head and the target tissue through the three-dimensional photoacoustic image;
step 6, after the three-dimensional photoacoustic image observes the relative positions of the target and the needle, the angle of the needle can be adjusted by sliding the hole site plate 3 on the rigid hemispheroid 4, the whole rigid hemispheroid 4 is rotated, the direction is adjusted, after a proper angle is found, the needle is pushed, the needle is inserted into the target tissue, the position condition of the needle in the target tissue is seen in real time through the three-dimensional photoacoustic image, and after the position reaches the proper position, injection or extraction operation is carried out;
And 7, after the step is finished, the needle is withdrawn, the rigid hemispheroids 4 are separated from the target position, and the target position is sterilized and hemostatic.
Description of working principle: in use, the plastic channel tube 21 is screwed onto the hole on the movable hole site plate 3, and then the flexible transparent film 7 is unfolded and pressed against the lower edge of the rigid hemisphere 4, and a water containing chamber is formed between the flexible transparent water containing structure and the rigid hemisphere 4;
the rigid hemispheroids 4 are filled with water through the water injection holes, and the flexible transparent films 7 protrude downwards due to the gravity and the pressure of the water;
The rigid hemispheroid 4 is buckled on a target position, the sphere center of the rigid hemispheroid 4 is placed at a position to be injected or extracted, and the specific position of the needle head of the injector 1 is observed through a video image module;
Starting a laser source and a photoacoustic host system, and starting polishing and acquisition and reconstruction imaging; at this time, the laser emitting part 6 reflects pulse laser to irradiate the sphere center part of the rigid hemisphere 4, the laser irradiates the target area through the flexible transparent film 7, enters the inside of the target through scattering, and causes transient light absorption and thermal expansion due to the absorption of scattered laser energy by substances in the inside of the target to generate ultrasonic waves, the transducer array element 5 on the rigid hemisphere 4 receives ultrasonic signals and inputs the ultrasonic signals into the photoacoustic host system, and the photoacoustic host system displays a three-dimensional photoacoustic image on a display screen after analog-digital conversion, data preprocessing, image reconstruction, image processing and display;
The injector 1 or the extractor is inserted through the plastic channel tube 21 from the opening of the hole site plate 3 on the rigid hemisphere 4, the needle head is put down from the flexible channel tube 22, the video image in the rigid hemisphere 4 collected by the video image module can be seen from the display, the position of the needle head is observed, and the positional relationship between the needle head and the target tissue is seen through the three-dimensional photoacoustic image;
After the three-dimensional photoacoustic image observes the relative positions of the target and the needle, the angle of the needle can be adjusted by sliding the hole site plate 3 on the rigid hemispheroid 4, the whole rigid hemispheroid 4 is rotated, the direction is adjusted, after a proper angle is found, the needle is pushed, the needle is inserted into the target tissue, the position condition of the needle in the target tissue is seen in real time through the three-dimensional photoacoustic image, and after the proper position is reached, injection or extraction operation is carried out;
After completion, the needle is withdrawn, the rigid hemisphere 4 is detached from the target site and the target site is sterilized and hemostatic.
The preferred embodiments of the present invention have been described in detail above with reference to the accompanying drawings, but the present invention is not limited to the specific details of the embodiments, and various equivalent changes can be made to the technical solutions of the present invention within the scope of the technical concept of the present invention, and all such equivalent changes belong to the protection scope of the present invention.
Claims (6)
1. An injection and extraction device based on photoacoustic three-dimensional imaging, which is characterized by comprising:
the cambered surface array ultrasonic probe comprises a rigid hemisphere (4), and a transducer array element (5) and a laser emitting part (6) which are connected with the rigid hemisphere (4);
A chute is formed in the rigid hemispheroid (4), and a hole site plate (3) is arranged in the chute;
The hole site plate (3) is provided with an opening;
The flexible transparent water-holding structure comprises a flexible transparent film (7) matched with the rigid hemispheroids (4), and a containing channel (2) with one end communicated with the flexible transparent film (7) and the other end connected with the hole site plate (3);
the injector (1) passes through the opening and is placed in the accommodating channel (2);
The accommodating channel (2) comprises a flexible channel tube (22) connected to the center of the flexible transparent film (7), and a plastic channel tube (21) with one end connected with the flexible channel tube (22) and the other end connected with the hole site plate (3);
The injector (1) is arranged in the plastic channel tube (21);
The connecting threads are arranged on the open holes;
One end of the plastic channel pipe (21) far away from the flexible channel pipe (22) is provided with a fixed thread matched with the connecting thread;
the rigid hemispheroids (4) are internally provided with video image modules;
The video image module comprises a miniature camera connected with the display and is arranged on the rigid hemisphere (4) in a built-in manner and used for collecting image information in the rigid hemisphere (4).
2. The injection and extraction device based on photoacoustic three-dimensional imaging of claim 1, wherein: the transducer array elements (5) are designed into a plurality of groups and are uniformly distributed on the rigid hemispheres (4);
the laser emitting parts (6) are at least designed singly, and the laser emitting direction is the center of the rigid hemispheroid (4) or the periphery of the center of the rigid hemispheroid (4).
3. The injection and extraction device based on photoacoustic three-dimensional imaging of claim 2, wherein: the laser emitting piece (6) is externally connected with a laser source;
the laser source comprises a nanosecond pulse generator connected to a laser emitter (6).
4. The injection and extraction device based on photoacoustic three-dimensional imaging of claim 1, wherein: the rigid hemispheroids (4) are provided with water injection holes.
5. The injection and extraction device based on photoacoustic three-dimensional imaging of claim 1, wherein: the flexible transparent film (7) is made of flexible transparent materials.
6. The injection and extraction device based on photoacoustic three-dimensional imaging of claim 1, wherein: the cambered surface array ultrasonic probe is externally connected with a photoacoustic host system;
the photoacoustic host system comprises a computer, a display and a data acquisition module;
the signal interface on the data acquisition module is connected to each transducer array element (5), analog signals are acquired and converted into digital signals, and finally the digital signals are transmitted to a computer for reconstruction calculation, and the display displays images.
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| WO2011100753A2 (en) * | 2010-02-15 | 2011-08-18 | The Johns Hopkins University | Interventional photoacoustic imaging system |
| CN110384581A (en) * | 2019-07-17 | 2019-10-29 | 曹地 | Injection device in a kind of Brilliant Eyes |
| KR20210061881A (en) * | 2019-11-20 | 2021-05-28 | 전남대학교산학협력단 | Photoacoustic image based laparoscopy apparatus and apparatus for searching catheter in blood vessel based on photoacoustic images |
| EP3932295A1 (en) * | 2020-06-30 | 2022-01-05 | Universität Zürich | Optoacoustic tomography method of a living organism, 2d- or 3d opotacoustic images, 2d- or 3d blood flow and light fluence images and a photoabsorbing agent for the use in an optoacoustic method |
| CN115778501A (en) * | 2022-11-23 | 2023-03-14 | 安徽普盛医疗科技有限公司 | Puncture assistor for interventional therapy |
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