CN116731855B - Production equipment of bovine bone collagen peptide - Google Patents

Production equipment of bovine bone collagen peptide Download PDF

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CN116731855B
CN116731855B CN202310806081.3A CN202310806081A CN116731855B CN 116731855 B CN116731855 B CN 116731855B CN 202310806081 A CN202310806081 A CN 202310806081A CN 116731855 B CN116731855 B CN 116731855B
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wall
enzymolysis tank
heat supply
pipe
switch
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CN116731855A (en
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石丰
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Jilin Peptide Valley Bioengineering Co ltd
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Jilin Peptide Valley Bioengineering Co ltd
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00Bioreactors or fermenters specially adapted for specific uses
    • C12M21/18Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02Stirrer or mobile mixing elements
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18Heat exchange systems, e.g. heat jackets or outer envelopes
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/06Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/10Process efficiency

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Abstract

The utility model discloses production equipment and a production method of bovine bone collagen peptide, and relates to the technical field of bovine bone collagen peptide production. According to the utility model, the stirring mechanism is matched with the heat supply mechanism, the heated liquid in the heat supply cover heats the outside of the enzymolysis tank, the circulating pump pumps the heated liquid and supplies the heated liquid to the switching pipe through the liquid supply pipe, the connecting hose connected with the switching pipe is connected with the heat exchange main pipe, the stirring rod in the stirring mechanism can rotate to drive the stirring frame and the heat exchange main pipe to rotate reciprocally, the outside of the enzymolysis tank and the raw materials in the enzymolysis tank can be synchronously heated, the uniform heating is ensured, and the enzymolysis process of bovine collagen is promoted.

Description

Production equipment of bovine bone collagen peptide
Technical Field
The utility model relates to the technical field of bovine collagen peptide production, in particular to production equipment of bovine collagen peptide.
Background
Bovine collagen is a high molecular functional protein, and is rich in amino acids such as glycine, proline, hydroxyproline and the like required by human bodies. Bovine collagen peptide can promote collagen synthesis, shorten wound healing time, and increase local oxygen supply and angiogenesis.
For this, the utility model patent with the publication number of CN217188226U discloses a collagen peptide production device for promoting wound healing, and relates to the technical field of collagen peptide production equipment. The upper surface fixedly connected with extrusion cylinder of extrusion filter vat, the output of extrusion cylinder runs through the upper lateral wall of extrusion filter vat to fixedly connected with extrusion section of thick bamboo, the inboard of extrusion section of thick bamboo is provided with a plurality of extrusion piece, the below of extrusion section of thick bamboo is provided with extrusion filtration and accepts the mechanism. Be provided with the extrusion section of thick bamboo in extrusion filter vat, the lower surface of inboard pressurization slide at the extrusion section of thick bamboo is provided with a plurality of extrusion piece, is provided with a plurality of extrusion frame in the below of a plurality of extrusion piece, cuts apart the raw materials into a plurality of regions through a plurality of extrusion piece and a plurality of extrusion frame and extrudes to effectively avoid the raw materials too to pile up, influence extrusion effect, the liquid that the extrusion produced carries out primary filtration through the filter of extrusion frame lower extreme, enters into the filter screen through the feed-through hole, carries out secondary filtration.
The utility model patent with the publication number of CN107880114B discloses a bovine collagen peptide production device, the tank wall of the tank body comprises an outer wall, a heating plate and an inner wall from outside to inside, the heating plate is controlled by adopting an independent unit, a heating area can be adjusted according to the liquid level of reactants in the tank body, the energy consumption is reduced, meanwhile, the on-off of an electromagnet is convenient for the fixing and the dismounting of the heating plate, and the far infrared rays released by graphene have a catalytic effect on enzymolysis reaction in the tank body, so that the enzymolysis efficiency and speed are effectively improved. In addition, each tank body is connected with the annular groove in a matched mode through the annular strip, and is fixed through the fixing piece, and the fixing piece comprises a second cross rod, a connecting rod and a first cross rod which are sequentially connected in a pivoted mode. The production equipment is convenient to detach and assemble, is convenient and flexible to use, and can
The number of the tank bodies is adjusted according to the enzymolysis times, so that the process complexity in the production process is reduced.
The existing protein peptide production equipment is difficult to heat the outside of the tank body and the inside of the tank body simultaneously, so that the tank body is heated unevenly to influence the production process of the protein peptide, and meanwhile, in the protein peptide production process, the temperature of production raw materials with different depths in the tank body is difficult to measure, and the reaction temperature cannot be accurately mastered by personnel.
Disclosure of Invention
Aiming at the defects of the prior art, the utility model provides the production equipment of bovine bone collagen protein peptide, which solves the problems that the existing production equipment of protein peptide is difficult to heat the outside of a tank body and the inside of the tank body at the same time, so that the tank body is heated unevenly to influence the production process of protein peptide, and meanwhile, in the production process of protein peptide, the temperature of production raw materials with different depths in the tank body is difficult to measure, and the reaction temperature cannot be accurately mastered by personnel.
In order to achieve the above purpose, the utility model is realized by the following technical scheme: the production equipment of the bovine bone collagen peptide comprises an enzymolysis tank, wherein a stirring mechanism is arranged in the middle of the top end of the enzymolysis tank, a heating mechanism is arranged on the outer wall of the enzymolysis tank, and a temperature measuring mechanism is arranged on one side of the top end of the enzymolysis tank;
the stirring mechanism comprises a working box, a supporting table is fixedly arranged on one side of the inner wall of the working box, a driving motor is mounted at the top end of the supporting table, a crank is fixedly arranged at the output end of the driving motor, a connecting rod is rotatably connected to one side of the crank, a supporting lug is rotatably connected to one end of the connecting rod, a driving rack is fixedly arranged on one side of the supporting lug, a driving gear is meshed with one side of the driving rack, a transmission shaft is fixedly arranged at the bottom end of the driving gear, stirring rods are fixedly arranged at the bottom end of the transmission shaft, stirring frames are fixedly arranged on two sides of the stirring rods, a plurality of arc-shaped fixing blocks which are uniformly distributed are fixedly arranged on one side of each stirring frame, a convex sliding strip is fixedly arranged on the other side of the driving rack, the outer wall of the convex sliding strip is slidably connected with a convex sliding groove formed in the other side of the inner wall of the working box, the outer wall of the transmission shaft is rotatably connected with the bottom of the inner wall of the working box through a bearing, and the stirring rod is rotatably connected to the top of the inner wall of the enzymolysis tank through the bearing;
the heat supply mechanism comprises a heat supply cover, the heat supply cover and the enzymolysis tank form a heating cavity, a liquid suction pipe is fixedly arranged in a liquid suction hole formed in one side of the top end of the heat supply cover, one end of the liquid suction pipe is fixedly communicated with a liquid inlet end of a circulating pump, a liquid supply pipe is fixedly communicated with a liquid outlet end of the circulating pump, two connecting holes formed in the top of the inner wall of the enzymolysis tank are fixedly provided with transfer pipes, one of the two connecting holes is fixedly communicated with one end of the liquid supply pipe, the bottom ends of the two transfer pipes are fixedly communicated with connecting hoses, the bottom ends of the two connecting hoses are respectively fixedly communicated with the two ends of a heat exchange main pipe, the inner wall of a plurality of arc-shaped fixing blocks are fixedly connected with the outer wall of the heat exchange main pipe, a plurality of heat exchange auxiliary pipes which are uniformly distributed are fixedly communicated with the surface of the heat exchange main pipe, the top ends of the other transfer pipe are fixedly communicated with a liquid return pipe, the outer wall of the liquid return pipe is fixedly connected with a liquid return hole formed in the other side of the top end of the heat supply cover, one side of the inner wall of the heat supply cover is rotationally connected with a rotating shaft through a bearing, one end of the rotating shaft is fixedly provided with an impeller, the bottom of the inner wall of the heat supply cover is provided with an electric heating pipe, the middle part of the bottom end of the enzymolysis tank is fixedly communicated with a discharging pipe, the outer wall of the discharging pipe is fixedly connected with a through hole formed in the middle part of the bottom end of the heat supply cover, the bottom end of the discharging pipe is fixedly communicated with an electromagnetic valve, one side of the top end of the enzymolysis tank is fixedly communicated with a feed inlet, one side of the top end of the feed inlet is hinged with a sealing cover, a plurality of first openings formed in the outer wall of the feed inlet are rotationally connected with threaded columns, the bottoms of the outer walls of the threaded columns are respectively connected with a plurality of second openings formed in the outer wall of the sealing cover in a penetrating mode, the top of the outer wall of each threaded column is connected with a threaded cap in a threaded manner, one side of the heat supply cover is fixedly communicated with a liquid discharge valve, one corner of the top of the heat supply cover is fixedly communicated with a control valve, the top of the control valve is fixedly communicated with a liquid adding hopper, four corners of the bottom of the heat supply cover are fixedly provided with supporting legs, one side of the heat supply cover is fixedly provided with a mounting plate, and the top of the mounting plate is provided with a circulating pump;
the other side at enzymolysis tank top has seted up the temperature measurement hole, temperature measuring mechanism includes the fixed block, the fixed braced frame that is equipped with in one side at fixed block top, step motor is installed on the top of braced frame, and the middle part of braced frame inner wall rotates and is connected with drive screw, step motor's output and drive screw's bottom fixed connection, drive screw outer wall's top threaded connection has the drive swivel nut, one side of drive swivel nut is fixed and is equipped with the thermometer.
Further, the opposite side on fixed block top has seted up the detection hole, the fixed intercommunication in one side of detection hole has the sealing washer, and the detection hole link up with the temperature measurement hole mutually, movable cavity has been seted up to the inside of fixed block, movable cavity is linked together with the detection hole, one side interlude of movable cavity inner wall is equipped with the ejector pad, one side of ejector pad is fixed and is equipped with the sealing plug, and the opposite side of ejector pad is connected with drive screw through the bearing rotation, drive screw threaded connection that one side of outer wall and fixed block was seted up of drive screw, and the one end of drive screw is fixed and is equipped with the carousel.
Further, the both sides of carriage inner wall are all fixed and are equipped with the slide bar, every the equal sliding connection in top of slide bar outer wall has the sliding sleeve, every the one side of sliding sleeve is all fixed and is equipped with the connecting block, two the one end of connecting block respectively with the both sides fixed connection of drive swivel nut.
Further, a switch panel is fixedly arranged on one side of the enzymolysis tank, a driving motor switch, a circulating pump switch, an electric heating pipe switch, a stepping motor switch, a thermometer switch and an electromagnetic valve switch are fixedly arranged on the surface of the switch panel, and the driving motor, the circulating pump, the electric heating pipe, the stepping motor, the thermometer and the electromagnetic valve are electrically connected with an external power supply through the driving motor switch, the circulating pump switch, the electric heating pipe switch, the stepping motor switch, the thermometer switch and the electromagnetic valve switch respectively.
The production method of bovine collagen peptide, which uses the production equipment of bovine collagen peptide, comprises the following steps:
s1, ensuring the cleanness and sterility of an enzymolysis tank, closing an electromagnetic valve, and adding heat conduction oil into a heat supply cover through a liquid adding hopper;
s2, removing impurities from the beef bones, cleaning, crushing, performing oil-water separation on the crushed beef bones to obtain cooking liquor, obtaining production stock solution, opening a sealing cover, and adding the production stock solution into an enzymolysis tank through a feed inlet;
s3, adding collagen protease into the enzymolysis tank, heating the outside of the enzymolysis tank through a heat supply mechanism, extracting heat conduction oil to enter a heat exchange main pipe to heat internal raw materials, and enabling a stirring rod to drive a stirring frame to stir the raw materials through a stirring mechanism, so that the movement of the heat exchange main pipe can be ensured, and bovine bone collagen peptide is generated after enzymolysis is finished;
s4, in the enzymolysis process of the raw materials, the thermometer in the temperature measuring mechanism can extend to different parts of the enzymolysis tank, and temperature measurement is carried out on the raw materials in different depths in the enzymolysis tank;
s5, filtering and concentrating the bovine collagen peptide in the enzymolysis tank to obtain bovine collagen peptide concentrated solution.
The utility model has the following beneficial effects:
1. this production facility of bovine bone collagen peptide, through rabbling mechanism and heat supply mechanism cooperation, the liquid of heating in the heat supply cover is to enzymolysis tank external heating, and circulating pump draws heating liquid and is supplied with the transfer pipe through the liquid supply pipe, and the coupling hose of transfer union coupling is responsible for with the heat transfer and is connected, and the rotation of puddler can drive the reciprocating rotation of stirring frame and heat transfer in the rabbling mechanism, can carry out synchronous heating to the outside of enzymolysis tank and the interior raw materials of enzymolysis tank, guarantees to be heated evenly, promotes bovine bone collagen enzymolysis process.
2. This production facility of bovine bone collagen peptide, the crank that driving motor connects rotates with the connecting rod to be connected, and the supporting lug that the connecting rod rotated to be connected is connected with drive rack, and drive rack and epaxial drive gear engagement of transmission, puddler are connected with the stirring frame, can guarantee that the stirring frame is less than one hundred eighty degrees and carry out positive and negative reciprocating rotation, can guarantee that the interior raw materials of enzymolysis tank mix fully, guarantee enzymolysis process.
3. In the production equipment of the bovine bone collagen peptide, a detection hole formed in a fixed block is communicated with a temperature measurement hole formed in an enzymolysis tank, a driving screw sleeve in threaded connection with a driving screw is connected with a thermometer, a pushing block is inserted in a movable cavity formed in the fixed block, the pushing block is connected with a sealing plug, the pushing block is rotationally connected with a driving screw, and the thermometer can be driven to extend to different depths of the enzymolysis tank in the reaction process, so that personnel can accurately master the temperature of each place.
Drawings
The accompanying drawings, which are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate embodiments of the utility model and together with the description serve to explain the utility model and do not constitute a limitation on the utility model. In the drawings:
FIG. 1 is a schematic diagram of the structure of the present utility model;
FIG. 2 is a schematic diagram of a connection structure between an enzymolysis tank and a temperature measuring mechanism;
FIG. 3 is a schematic diagram of a connection structure between an enzymolysis tank and a heating mechanism;
FIG. 4 is a schematic diagram of a connection structure of the stirring mechanism and the heating mechanism of the present utility model;
FIG. 5 is a schematic structural view of the stirring mechanism of the present utility model;
FIG. 6 is a schematic view of the connection structure of the stirring frame of the present utility model;
FIG. 7 is a schematic view showing the internal structure of the heat supply cover of the present utility model;
FIG. 8 is a schematic diagram of a temperature measuring mechanism according to the present utility model;
FIG. 9 is an enlarged schematic view of the present utility model at A in 8;
fig. 10 is a schematic view of the internal structure of the fixing block of the present utility model.
In the figure: 1. an enzymolysis tank; 2. a stirring mechanism; 201. a working box; 202. a support table; 203. a driving motor; 204. a crank; 205. a connecting rod; 206. a support ear; 207. a drive rack; 208. a convex slide; 209. a drive gear; 210. a transmission shaft; 211. a stirring rod; 212. a stirring rack; 213. an arc-shaped fixed block; 3. a heating mechanism; 301. a heating cover; 302. a liquid discharge valve; 303. a mounting plate; 304. a circulation pump; 305. a liquid suction pipe; 306. a liquid supply pipe; 307. a transfer tube; 308. a liquid return pipe; 309. a liquid adding hopper; 310. a connecting hose; 311. a heat exchange main pipe; 312. a heat exchange auxiliary pipe; 313. a rotating shaft; 314. an impeller; 315. an electric heating tube; 4. a temperature measuring mechanism; 401. a fixed block; 402. a seal ring; 403. driving a screw; 404. a turntable; 405. a support frame; 406. driving a screw rod; 407. a slide bar; 408. a stepping motor; 409. a thermometer; 410. driving the screw sleeve; 411. a sliding sleeve; 412. a connecting block; 413. a movable cavity; 414. a pushing block; 415. a sealing plug; 5. support legs; 6. a discharge pipe; 7. an electromagnetic valve; 8. a feed inlet; 9. sealing cover; 10. and a temperature measuring hole.
Detailed Description
In order to more clearly illustrate the general inventive concept, a detailed description is given below by way of example with reference to the accompanying drawings.
As shown in fig. 1 to 10, the embodiment of the utility model provides production equipment of bovine bone collagen peptide, which comprises an enzymolysis tank 1, wherein a stirring mechanism 2 is arranged in the middle of the top end of the enzymolysis tank 1, a heating mechanism 3 is arranged on the outer wall of the enzymolysis tank 1, and a temperature measuring mechanism 4 is arranged on one side of the top end of the enzymolysis tank 1;
the stirring mechanism 2 comprises a working box 201, a supporting table 202 is fixedly arranged on one side of the inner wall of the working box 201, a driving motor 203 is installed at the top end of the supporting table 202, a crank 204 is fixedly arranged at the output end of the driving motor 203, a connecting rod 205 is rotatably connected to one side of the crank 204, a supporting lug 206 is rotatably connected to one end of the connecting rod 205, a driving rack 207 is fixedly arranged on one side of the supporting lug 206, a driving gear 209 is meshed with one side of the driving rack 207, a transmission shaft 210 is fixedly arranged at the bottom end of the driving gear 209, a stirring rod 211 is fixedly arranged at the bottom end of the transmission shaft 210, stirring frames 212 are fixedly arranged at two sides of the stirring rod 211, and a plurality of uniformly distributed arc-shaped fixing blocks 213 are fixedly arranged on one side of each stirring frame 212;
the heat supply mechanism 3 comprises a heat supply cover 301, the heat supply cover 301 and the enzymolysis tank 1 form a heating cavity, a liquid suction hole formed in one side of the top end of the heat supply cover 301 is fixedly provided with a liquid suction pipe 305, one end of the liquid suction pipe 305 is fixedly communicated with the liquid inlet end of a circulating pump 304, the liquid outlet end of the circulating pump 304 is fixedly communicated with a liquid supply pipe 306, two connecting holes formed in the top of the inner wall of the enzymolysis tank 1 are fixedly provided with transfer pipes 307, the top end of one transfer pipe 307 is fixedly communicated with one end of the liquid supply pipe 306, the bottom ends of the two transfer pipes 307 are fixedly communicated with connecting hoses 310, the bottom ends of the two connecting hoses 310 are fixedly communicated with the two ends of a heat exchange main pipe 311 respectively, the inner walls of a plurality of arc-shaped fixing blocks 213 are fixedly connected with the outer wall of the heat exchange main pipe 311, and the surface of the heat exchange main pipe 311 is fixedly communicated with a plurality of evenly distributed heat exchange auxiliary pipes 312.
The opposite side of drive rack 207 is fixed and is equipped with convex draw runner 208, the outer wall of convex draw runner 208 and the convex spout sliding connection that the opposite side of working box 201 inner wall was seted up, the outer wall of transmission shaft 210 passes through the bearing and rotates with the bottom of working box 201 inner wall to be connected, the top of enzymolysis tank 1 inner wall is rotated through the bearing and is connected with puddler 211, the top fixed intercommunication of another transfer pipe 307 has liquid return pipe 308, liquid return hole fixed connection that the opposite side on liquid return pipe 308's outer wall and heat supply cover 301 top was seted up, one side of heat supply cover 301 inner wall is rotated through the bearing and is connected with pivot 313, the fixed impeller 314 that is equipped with in one end of pivot 313, electric heating pipe 315 is installed to the bottom of heat supply cover 301 inner wall, the fixed intercommunication in middle part of enzymolysis tank 1 bottom has discharging pipe 6, the fixed connection of the through-hole fixed connection of the outer wall and the middle part of heat supply cover 301 bottom, the fixed intercommunication of discharging pipe 6 has solenoid valve 7, one side fixed intercommunication in enzymolysis tank 1 top has charge door 8, one side of charge door 8 top articulates there is sealed lid 9, a plurality of first openings that the outer wall of charge door 8 set up, all rotate and be connected with screw thread post in the first opening, the bottom of a plurality of sealed lid and the top side 9 and a plurality of threaded post's are connected with the second side of threaded cap 301, top end cap 301 is equipped with the fixed connection of screw thread side of a top side of a control valve, the top end cap 301 is equipped with the screw cap, the top side of the fixed mounting plate 303, the top end of the top valve is connected with the top valve 303, the top is connected with the top end of the top valve 303, the top of the top valve is connected with the top valve, and the top of the top cap is connected with the top cap and has and the top cap and the top.
The other side of the top end of the enzymolysis tank 1 is provided with a temperature measuring hole 10, the temperature measuring mechanism 4 comprises a fixed block 401, one side of the top end of the fixed block 401 is fixedly provided with a supporting frame 405, the top end of the supporting frame 405 is provided with a stepping motor 408, the middle part of the inner wall of the supporting frame 405 is rotationally connected with a driving screw 406, the output end of the stepping motor 408 is fixedly connected with the bottom end of the driving screw 406, the top thread of the outer wall of the driving screw 406 is connected with a driving screw sleeve 410, one side of the driving screw sleeve 410 is fixedly provided with a thermometer 409, the other side of the top end of the fixed block 401 is provided with a detecting hole, one side of the detecting hole is fixedly communicated with a sealing ring 402, the detecting hole is communicated with the temperature measuring hole 10, the inside of the fixed block 401 is provided with a movable cavity 413, one side of the inner wall of the movable cavity 413 is provided with a pushing block 414 in a penetrating way, one side of the pushing block 414 is fixedly provided with a sealing plug 415, the other side of the push block 414 is rotatably connected with a driving screw 403 through a bearing, the outer wall of the driving screw 403 is in threaded connection with a driving screw hole formed in one side of the fixed block 401, one end of the driving screw 403 is fixedly provided with a rotary table 404, two sides of the inner wall of the supporting frame 405 are fixedly provided with sliding rods 407, the top of the outer wall of each sliding rod 407 is fixedly connected with a sliding sleeve 411, one side of each sliding sleeve 411 is fixedly provided with a connecting block 412, one end of each connecting block 412 is fixedly connected with two sides of the driving screw sleeve 410 respectively, one side of the enzymolysis tank 1 is fixedly provided with a switch panel, the surface of the switch panel is fixedly provided with a driving motor switch, a circulating pump switch, an electric heating pipe switch, a stepping motor switch, a thermometer switch and an electromagnetic valve switch, and the driving motor 203, the circulating pump 304, the electric heating pipe 315, the stepping motor 408, the thermometer 409 and the electromagnetic valve 7 are respectively connected with the driving motor switch and the circulating pump switch through the driving motor switch, the circulating pump switch, the electric heating tube switch, the stepping motor switch, the thermometer switch and the electromagnetic valve switch are electrically connected with an external power supply.
The production method of bovine collagen peptide, which uses the production equipment of bovine collagen peptide, comprises the following steps:
s1, ensuring the cleanness and sterility of an enzymolysis tank, closing an electromagnetic valve, and adding heat conduction oil into a heat supply cover through a liquid adding hopper;
s2, removing impurities from the beef bones, cleaning, crushing, performing oil-water separation on the crushed beef bones to obtain cooking liquor, obtaining production stock solution, opening a sealing cover, and adding the production stock solution into an enzymolysis tank through a feed inlet;
s3, adding collagen protease into the enzymolysis tank, heating the outside of the enzymolysis tank through a heat supply mechanism, extracting heat conduction oil to enter a heat exchange main pipe to heat internal raw materials, and enabling a stirring rod to drive a stirring frame to stir the raw materials through a stirring mechanism, so that the movement of the heat exchange main pipe can be ensured, and bovine bone collagen peptide is generated after enzymolysis is finished;
s4, in the enzymolysis process of the raw materials, the thermometer in the temperature measuring mechanism can extend to different parts of the enzymolysis tank, and temperature measurement is carried out on the raw materials in different depths in the enzymolysis tank;
s5, filtering and concentrating the bovine collagen peptide in the enzymolysis tank to obtain bovine collagen peptide concentrated solution.
When the enzymolysis tank 1 is used, the hinged sealing cover 9 of the feed inlet 8 is opened, reaction raw materials are added into the enzymolysis tank 1, meanwhile, heat conduction oil is added into the heat supply cover 301 through the liquid adding hopper 309, the electric heating pipe 315 works to heat the heat conduction oil, the heat conduction oil in the heat supply cover 301 can be pumped by the circulating pump 304 through the liquid pumping pipe 305, the heat conduction oil is supplied to the switching pipe 307 through the liquid supply pipe 306, the heat exchange main pipe 311 can be supplied through the connecting hose 310, the raw materials in the enzymolysis tank 1 can be heated through the heat exchange main pipe 311 and the heat exchange auxiliary pipe 312, the raw materials are synchronously heated from the outside and the inside of the enzymolysis tank, the heat conduction oil enters the heat supply cover 301 through the liquid return pipe 308, the heat conduction oil sprayed out by the liquid return pipe 308 acts on the impeller 314, and the impeller 314 rotates, so that the heat conduction oil can fully move in the heat supply cover 301, and the heat is uniformly heated;
when enzymolysis is performed, the driving motor 203 on the supporting table 202 in the stirring mechanism 2 drives the crank 204 to rotate, the crank 204 drives the connecting rod 205, the connecting rod 205 acts on the supporting lug 206 connected with the driving rack 207, the driving rack 207 can reciprocate, and further the driving gear 209 is driven to reciprocate positively and negatively, the number of teeth of the driving rack 207 is lower than half of the number of teeth of the driving gear 209, the rotation angle of the driving gear 209 is ensured to be lower than one hundred eighty degrees, the transmission shaft 210 drives the stirring rod 211, the stirring rack 212 can reciprocate, raw materials in the enzymolysis tank 1 can be sufficiently stirred, the arc-shaped fixing block 213 connected with the stirring rack 212 is connected with the heat exchange main pipe 311, the connecting hose 310 connected with the heat exchange main pipe 311 is connected with the switching pipe 307, and the heat exchange main pipe 311 is ensured to reciprocate positively and negatively to rotate less than one hundred eighty degrees in the enzymolysis tank 1, and the raw materials in the enzymolysis tank 1 are ensured to be heated sufficiently;
in the enzymolysis process, personnel can rotate the driving screw 403 through the turntable 404, and then drive the push block 414 in the movable cavity 413 to move, the push block 414 drives the sealing plug 415 to move, and then the detection hole formed by the fixed block 401 is communicated with the temperature measuring hole 10, the stepping motor 408 is opened, the stepping motor 408 drives the driving screw 406 in the supporting frame 405, the driving screw sleeve 410 on the driving screw 406 drives the thermometer 409 to descend, and the thermometer 409 extends into the enzymolysis tank 1 through the detection hole and the temperature measuring hole 10, so that raw materials with different depths of the enzymolysis tank 1 can be measured.

Claims (5)

1. The production equipment of bovine bone collagen peptide comprises an enzymolysis tank (1), wherein a stirring mechanism (2) is arranged in the middle of the top end of the enzymolysis tank (1), a heat supply mechanism (3) is arranged on the outer wall of the enzymolysis tank (1), and a temperature measuring mechanism (4) is arranged on one side of the top end of the enzymolysis tank (1), and is characterized in that:
the stirring mechanism (2) comprises a working box (201), a supporting table (202) is fixedly arranged on one side of the inner wall of the working box (201), a driving motor (203) is arranged at the top end of the supporting table (202), a crank (204) is fixedly arranged at the output end of the driving motor (203), a connecting rod (205) is rotatably connected to one side of the crank (204), a supporting lug (206) is rotatably connected to one end of the connecting rod (205), a driving rack (207) is fixedly arranged on one side of the supporting lug (206), a driving gear (209) is meshed on one side of the driving rack (207), a transmission shaft (210) is fixedly arranged at the bottom end of the driving gear (209), stirring rods (211) are fixedly arranged at the bottom end of the transmission shaft (210), stirring racks (212) are fixedly arranged on two sides of the stirring rods (211), a plurality of arc-shaped fixing blocks (213) which are uniformly distributed are fixedly arranged on one side of each stirring rack (212), a convex sliding bar (208) is fixedly arranged on the other side of the driving rack (207), the outer wall of the convex sliding bar (208) is fixedly connected with the outer wall of the inner wall of the working box (201) through a sliding groove (201), the top of the inner wall of the enzymolysis tank (1) is rotatably connected with a stirring rod (211) through a bearing;
the heat supply mechanism (3) comprises a heat supply cover (301), the heat supply cover (301) and the enzymolysis tank (1) form a heating cavity, a liquid suction pipe (305) is fixedly arranged in a liquid suction hole formed in one side of the top end of the heat supply cover (301), one end of the liquid suction pipe (305) is fixedly communicated with the liquid inlet end of a circulating pump (304), a liquid supply pipe (306) is fixedly communicated with the liquid outlet end of the circulating pump (304), two connecting holes formed in the top of the inner wall of the enzymolysis tank (1) are fixedly provided with a transfer pipe (307), one of the top ends of the transfer pipe (307) are fixedly communicated with one end of the liquid supply pipe (306), the bottom ends of the two transfer pipes (307) are fixedly communicated with a connecting hose (310), the bottom ends of the connecting hoses (310) are fixedly communicated with the two ends of a heat exchange main pipe (311) respectively, the inner walls of a plurality of arc-shaped fixing blocks (213) are fixedly connected with the outer wall of the heat exchange main pipe (311), a plurality of uniform heat exchange pipes (311) are fixedly communicated with one surface of the other side of the heat exchange pipes (307), one side of the heat supply pipe (307) is fixedly communicated with the other side of the heat supply pipe (301) through the bearing (308), the utility model discloses a heat supply system, including a heat supply cover (301), a heat supply pump (301), a circulating pump (303), a circulating pump (301), a sealing cover (9), a plurality of first openings, a plurality of second openings, a discharging valve (302), a solenoid valve (7), a control valve, a plurality of sealing caps (309), a plurality of screw columns are fixedly connected to the bottom of the inner wall of the heat supply cover (301), a plurality of second openings are respectively arranged on the bottom of the outer wall of the screw columns, the top of each screw column is fixedly connected with the screw caps, one side of the heat supply cover (301) is fixedly connected with the liquid discharging valve (302), one corner of the top of the heat supply cover (301) is fixedly connected with the control valve, the top of the control valve (309) is fixedly connected with the corner of the top of the heat supply cover (301), and the four mounting plates (303) are fixedly connected with the top of the circulating pump (301);
temperature measurement hole (10) have been seted up to the opposite side on enzymolysis tank (1) top, temperature measurement mechanism (4) are including fixed block (401), one side on fixed block (401) top is fixed to be equipped with braced frame (405), step motor (408) are installed on the top of braced frame (405), and the middle part rotation of braced frame (405) inner wall is connected with drive lead screw (406), the output of step motor (408) and the bottom fixed connection of drive lead screw (406), the top threaded connection of drive lead screw (406) outer wall has drive swivel nut (410), one side of drive swivel nut (410) is fixed and is equipped with thermometer (409).
2. The production apparatus of bovine collagen peptide according to claim 1, wherein: the utility model discloses a measuring device, including fixed block (401) and fixed screw, the opposite side on fixed block (401) top has seted up the detection hole, the fixed intercommunication in one side of detection hole has sealing washer (402), and detects hole and temperature measurement hole (10) and link up mutually, movable cavity (413) have been seted up to the inside of fixed block (401), movable cavity (413) are linked together with the detection hole, one side interlude of movable cavity (413) inner wall is equipped with ejector pad (414), one side of ejector pad (414) is fixed and is equipped with sealing plug (415), and the opposite side of ejector pad (414) is connected with drive screw (403) through the bearing rotation, drive screw threaded connection that one side was seted up to the outer wall of drive screw (403) and fixed block (401), and the one end of drive screw (403) is fixed and is equipped with carousel (404).
3. The production apparatus of bovine collagen peptide according to claim 1, wherein: slide bars (407) are fixedly arranged on two sides of the inner wall of the supporting frame (405), the top of the outer wall of each slide bar (407) is slidably connected with a sliding sleeve (411), one side of each sliding sleeve (411) is fixedly provided with a connecting block (412), and one ends of the two connecting blocks (412) are fixedly connected with two sides of the driving screw sleeve (410) respectively.
4. The production apparatus of bovine collagen peptide according to claim 1, wherein: the enzymolysis tank (1) is fixed in one side and is equipped with switch panel, switch panel's fixed surface is equipped with driving motor switch, circulating pump switch, electric heating pipe switch, step motor switch, thermometer switch and solenoid valve switch, driving motor (203), circulating pump (304), electric heating pipe (315), step motor (408), thermometer (409) and solenoid valve (7) are respectively through driving motor switch, circulating pump switch, electric heating pipe switch, step motor switch, thermometer switch and solenoid valve switch and external power supply electric connection.
5. A method for producing bovine collagen peptide, characterized in that the production apparatus of bovine collagen peptide according to any one of claims 1 to 4 is used, comprising the steps of:
s1, ensuring the cleanness and sterility of an enzymolysis tank, closing an electromagnetic valve, and adding heat conduction oil into a heat supply cover through a liquid adding hopper;
s2, removing impurities from the beef bones, cleaning, crushing, performing oil-water separation on the crushed beef bones to obtain cooking liquor, obtaining production stock solution, opening a sealing cover, and adding the production stock solution into an enzymolysis tank through a feed inlet;
s3, adding collagen protease into the enzymolysis tank, heating the outside of the enzymolysis tank through a heat supply mechanism, extracting heat conduction oil to enter a heat exchange main pipe to heat internal raw materials, and enabling a stirring rod to drive a stirring frame to stir the raw materials through a stirring mechanism, so that the movement of the heat exchange main pipe can be ensured, and bovine bone collagen peptide is generated after enzymolysis is finished;
s4, in the enzymolysis process of the raw materials, the thermometer in the temperature measuring mechanism can extend to different parts of the enzymolysis tank, and temperature measurement is carried out on the raw materials in different depths in the enzymolysis tank;
s5, filtering and concentrating the bovine collagen peptide in the enzymolysis tank to obtain bovine collagen peptide concentrated solution.
CN202310806081.3A 2023-07-04 2023-07-04 Production equipment of bovine bone collagen peptide Active CN116731855B (en)

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Publication number Priority date Publication date Assignee Title
CN117778509B (en) * 2024-01-04 2024-06-07 吉林肽谷生物工程有限责任公司 Walnut peptide extraction method
CN117778180B (en) * 2024-02-27 2024-05-17 抚顺独凤轩骨神生物技术股份有限公司 Enzymolysis mixing equipment is used in production of micromolecule bone protein peptide

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009196131A (en) * 2008-02-20 2009-09-03 Kaneka Corp Pre-foaming method of foamable thermoplastic resin particle
WO2016083886A1 (en) * 2014-11-28 2016-06-02 Dariusz Piotr Okoniewski Device for the production of cheeses
CN107881103A (en) * 2017-12-13 2018-04-06 国药肽谷有限公司 A kind of donkey-hide gelatin peptide production equipment
CN211227090U (en) * 2019-10-29 2020-08-11 凤台县贵禧酱醋有限公司 Old vinegar processing is with quick degerming cooling device
CN111891582A (en) * 2020-07-20 2020-11-06 芜湖市鹏磊新材料有限公司 Bentonite powder drying tank structure
CN113352498A (en) * 2021-08-11 2021-09-07 东营辰鑫应用技术开发有限公司 Melting device for plastic production and processing and use method
CN216295835U (en) * 2021-08-29 2022-04-15 临沭县惠民无害化处理有限公司 Change system agitating unit for jar
CN217265777U (en) * 2022-01-21 2022-08-23 湖北健肽生物科技有限公司 Enzymolysis tank is used in filterable protein peptide production in two stirring areas
CN218688820U (en) * 2022-10-10 2023-03-24 广东澄轩建设工程有限公司 Prevent mixing stirring equipment of material caking
CN116218937A (en) * 2023-02-17 2023-06-06 吉林肽谷生物工程有限责任公司 Extraction method of blueberry peptide
US11666954B1 (en) * 2022-03-07 2023-06-06 Northeast Agricultural University Enzymatic hydrolysis device for livestock and poultry slaughter by-products
CN116640658A (en) * 2023-04-11 2023-08-25 国药肽谷有限公司 Bovine bone collagen peptide production device and production method thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190126216A1 (en) * 2017-10-30 2019-05-02 Paul Holly Container with Integrated Stirring Device

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009196131A (en) * 2008-02-20 2009-09-03 Kaneka Corp Pre-foaming method of foamable thermoplastic resin particle
WO2016083886A1 (en) * 2014-11-28 2016-06-02 Dariusz Piotr Okoniewski Device for the production of cheeses
CN107881103A (en) * 2017-12-13 2018-04-06 国药肽谷有限公司 A kind of donkey-hide gelatin peptide production equipment
CN211227090U (en) * 2019-10-29 2020-08-11 凤台县贵禧酱醋有限公司 Old vinegar processing is with quick degerming cooling device
CN111891582A (en) * 2020-07-20 2020-11-06 芜湖市鹏磊新材料有限公司 Bentonite powder drying tank structure
CN113352498A (en) * 2021-08-11 2021-09-07 东营辰鑫应用技术开发有限公司 Melting device for plastic production and processing and use method
CN216295835U (en) * 2021-08-29 2022-04-15 临沭县惠民无害化处理有限公司 Change system agitating unit for jar
CN217265777U (en) * 2022-01-21 2022-08-23 湖北健肽生物科技有限公司 Enzymolysis tank is used in filterable protein peptide production in two stirring areas
US11666954B1 (en) * 2022-03-07 2023-06-06 Northeast Agricultural University Enzymatic hydrolysis device for livestock and poultry slaughter by-products
CN218688820U (en) * 2022-10-10 2023-03-24 广东澄轩建设工程有限公司 Prevent mixing stirring equipment of material caking
CN116218937A (en) * 2023-02-17 2023-06-06 吉林肽谷生物工程有限责任公司 Extraction method of blueberry peptide
CN116640658A (en) * 2023-04-11 2023-08-25 国药肽谷有限公司 Bovine bone collagen peptide production device and production method thereof

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