CN116716082A - Solid gum for animal experiments and preparation and use methods thereof - Google Patents
Solid gum for animal experiments and preparation and use methods thereof Download PDFInfo
- Publication number
- CN116716082A CN116716082A CN202310818148.5A CN202310818148A CN116716082A CN 116716082 A CN116716082 A CN 116716082A CN 202310818148 A CN202310818148 A CN 202310818148A CN 116716082 A CN116716082 A CN 116716082A
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- gelatin
- zinc oxide
- water
- animal experiments
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- 241001465754 Metazoa Species 0.000 title claims abstract description 50
- 239000007787 solid Substances 0.000 title claims abstract description 50
- 238000002474 experimental method Methods 0.000 title claims abstract description 28
- 238000000034 method Methods 0.000 title claims abstract description 17
- 238000002360 preparation method Methods 0.000 title abstract description 9
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims abstract description 62
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 35
- 108010010803 Gelatin Proteins 0.000 claims abstract description 34
- 239000008273 gelatin Substances 0.000 claims abstract description 34
- 229920000159 gelatin Polymers 0.000 claims abstract description 34
- 235000019322 gelatine Nutrition 0.000 claims abstract description 34
- 235000011852 gelatine desserts Nutrition 0.000 claims abstract description 34
- 239000003292 glue Substances 0.000 claims abstract description 34
- 239000011787 zinc oxide Substances 0.000 claims abstract description 31
- 238000010438 heat treatment Methods 0.000 claims abstract description 18
- 239000002994 raw material Substances 0.000 claims abstract description 17
- 238000003756 stirring Methods 0.000 claims abstract description 9
- 238000009835 boiling Methods 0.000 claims abstract description 8
- 238000002156 mixing Methods 0.000 claims abstract description 8
- 238000001816 cooling Methods 0.000 claims abstract description 6
- IPCXNCATNBAPKW-UHFFFAOYSA-N zinc;hydrate Chemical compound O.[Zn] IPCXNCATNBAPKW-UHFFFAOYSA-N 0.000 claims abstract description 6
- 235000011837 pasties Nutrition 0.000 claims abstract description 4
- 239000000499 gel Substances 0.000 claims description 13
- 239000008367 deionised water Substances 0.000 claims description 7
- 229910021641 deionized water Inorganic materials 0.000 claims description 7
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical group [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 claims description 6
- 238000002844 melting Methods 0.000 claims description 5
- 230000008018 melting Effects 0.000 claims description 5
- 239000011248 coating agent Substances 0.000 claims description 4
- 238000000576 coating method Methods 0.000 claims description 4
- 230000001070 adhesive effect Effects 0.000 abstract description 13
- 239000004744 fabric Substances 0.000 abstract description 10
- 239000000853 adhesive Substances 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 7
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract description 2
- 230000009286 beneficial effect Effects 0.000 description 6
- 238000010411 cooking Methods 0.000 description 5
- 238000010171 animal model Methods 0.000 description 4
- 102000008186 Collagen Human genes 0.000 description 3
- 108010035532 Collagen Proteins 0.000 description 3
- 241000283973 Oryctolagus cuniculus Species 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 229920001436 collagen Polymers 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 239000008267 milk Substances 0.000 description 3
- 210000004080 milk Anatomy 0.000 description 3
- 235000013336 milk Nutrition 0.000 description 3
- 231100000252 nontoxic Toxicity 0.000 description 3
- 230000003000 nontoxic effect Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 241000238876 Acari Species 0.000 description 2
- 201000004624 Dermatitis Diseases 0.000 description 2
- 208000010201 Exanthema Diseases 0.000 description 2
- 241000699666 Mus <mouse, genus> Species 0.000 description 2
- 239000000084 colloidal system Substances 0.000 description 2
- 238000004132 cross linking Methods 0.000 description 2
- 244000078703 ectoparasite Species 0.000 description 2
- 201000005884 exanthem Diseases 0.000 description 2
- 244000045947 parasite Species 0.000 description 2
- 229920001184 polypeptide Polymers 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 206010037844 rash Diseases 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 241000238421 Arthropoda Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 208000032369 Primary transmission Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000002390 cell membrane structure Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 239000000416 hydrocolloid Substances 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 231100000046 skin rash Toxicity 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J189/00—Adhesives based on proteins; Adhesives based on derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J11/00—Features of adhesives not provided for in group C09J9/00, e.g. additives
- C09J11/02—Non-macromolecular additives
- C09J11/04—Non-macromolecular additives inorganic
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
- C08K3/20—Oxides; Hydroxides
- C08K3/22—Oxides; Hydroxides of metals
- C08K2003/2296—Oxides; Hydroxides of metals of zinc
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Adhesives Or Adhesive Processes (AREA)
Abstract
The application discloses a solid glue for animal experiments and a preparation and use method thereof, belonging to the technical field of adhesive materials, wherein the raw materials comprise gelatin, zinc oxide and water; wherein, the mass ratio of the zinc oxide to the gelatin is 1:1, the adding amount of water is 1-2 times of the total mass of the zinc oxide and the gelatin. The preparation method of the solid glue comprises the following steps: and mixing the raw materials to be pasty, heating and boiling in a water bath while stirring, and cooling to room temperature to obtain the solid glue. The solid glue can be used for bonding animal skin and cloth bag or container only after being heated and melted in the use process. The solid glue provided by the application has the characteristics of simple components, convenience in manufacturing, good fixing effect, capability of being used by heating for multiple times, safety and innocuity for animals, no harm to animal skin, and capability of being completely dissolved and eliminated by water.
Description
Technical Field
The application belongs to the technical field of adhesive materials, and particularly relates to a solid adhesive for animal experiments and a preparation and use method thereof.
Background
Ectoparasites are a class of vector arthropods that cause a variety of infectious diseases in humans and animals, including ticks, fleas, and the like, in which biting and sucking are the primary transmission means. In animal experiments, in the aspects of researching animal in-vitro insect expelling methods, preventing and treating ectoparasite-borne diseases and the like, the parasites (such as ticks) are fixed on the body surfaces of the unhairing animals for experimental observation and other researches, and the experiments are specifically needed to be carried out by adhering cloth bags or containers on the backs of rabbits and mice. However, the cloth bag and the container are extremely difficult to fix firmly, so that the risk of falling off the container and escaping of parasites is extremely high, experimental research is influenced, and once the ectoparasites escape to the external environment, certain biological potential safety hazards can be caused. In the prior art, commercial good ab glue or Kafute ab glue is often used for adhering the cloth bag or the container to the body surface of an animal, but the glue can cause skin allergy of the animal to be reddish and can not be eliminated, so that the experimental animal can not be reused.
Therefore, how to provide an adhesive which is safe and nontoxic to experimental animals and can firmly fix a container and a cloth bag is a technical problem which needs to be solved by the technicians in the field.
Disclosure of Invention
In order to solve the technical problems, the application provides the solid glue for animal experiments, which has moderate hardness and good adhesive property and use feeling.
In order to achieve the above purpose, the present application provides the following technical solutions:
the solid glue for animal experiments comprises gelatin, zinc oxide and water as raw materials;
wherein, the mass ratio of the zinc oxide to the gelatin is 1:1, the adding amount of water is 1-2 times of the total mass of the zinc oxide and the gelatin.
Preferably, the solid glue for animal experiments comprises the following raw materials in parts by weight: 100 parts of gelatin, 50-100 parts of zinc oxide and 200-400 parts of deionized water.
Further preferably, the solid glue for animal experiments comprises the following raw materials in parts by weight: 100 parts of gelatin, 100 parts of zinc oxide and 200 parts of deionized water.
The beneficial effects are that: gelatin, a macromolecular hydrocolloid, is the product of partial hydrolysis of collagen. The application selects gelatin as a main component of the adhesive, so that the prepared solid adhesive is safe and nontoxic to animal skin and does not cause skin allergy. Collagen molecules are helices formed by the intertwining of three polypeptide chains, and by processing in a technological process, collagen molecule helices are denatured into an alpha-component of a single polypeptide chain (alpha-chain) and a beta-component consisting of two alpha chains and a gamma-component consisting of three alpha chains, and molecular chain fragments interposed therebetween and smaller than the alpha-component or larger than the gamma-component, so that gelatin is a polydisperse system having a certain molecular weight distribution. The gelatin-based adhesive is easy to erode and destroy under the action of water and heat, so that the water resistance is poor and the adhesive property is often not ideal. According to the application, a proper amount of zinc oxide is added into gelatin, so that on one hand, the zinc oxide has the effects of sterilization and disinfection, and when microorganisms contact the surface of the gelatin, ions in the zinc oxide can be released to enter the inside of cells to interfere with the metabolic process of the cells and destroy the cell membrane structure of the cells, so that the microorganisms die, meanwhile, the zinc oxide can absorb bacterial metabolites and harmful substances, reduce the number of bacteria, and inhibit the growth of the microorganisms, so that the animal skin is protected from infection. On the other hand, zinc oxide can promote crosslinking among gel molecules and plays a role of a curing agent, and the defect of poor adhesive property of gelatin molecules due to low crosslinking degree can be overcome by controlling the addition amount of the zinc oxide, so that the prepared solid adhesive has good adhesive property and safety performance.
The application also provides another technical scheme: the preparation method of the solid gum for animal experiments comprises the following steps:
and mixing the raw materials to be pasty, heating and boiling in a water bath while stirring, and cooling to room temperature to obtain the solid glue.
The beneficial effects are that: the water bath is a heating method in a chemical laboratory by taking water as a heat transfer medium, and the method for treating the container product by using the water bath is as follows: the vessel to be water-bath is immersed in a larger vessel containing water and must not be in direct contact with the larger vessel. And then placing the larger container on a heat source for heating, stopping heating when the temperature reaches a proper temperature, and taking out the water bath container after cooling.
According to the application, after the raw materials are mixed, the raw materials are heated and boiled in a water bath while being stirred, firstly, zinc oxide and granular gelatin can be fully mixed, and secondly, the water bath is favorable for melting the gelatin and forming colloid with the zinc oxide.
Preferably, the boiling temperature is 100 ℃ and the boiling time is 40min.
The beneficial effects are that: at this temperature, gelatin can be completely converted into liquid state, and fully and uniformly mixed with zinc oxide and water, so that the prepared solid gel property can be optimized.
Preferably, the stirring rate is 200r/min.
The beneficial effects are that: the gelatin can be completely melted into liquid state by decocting at this temperature, and forms colloid with zinc oxide. The temperature of the inner container is lower than 100 ℃ in the water bath, so that dry paste caused by overhigh temperature can not be formed, and the melting of gelatin and the formation of colloidal substances of zinc oxide can be rapidly accelerated.
The application also provides a third technical scheme: the application method of the solid glue for animal experiments comprises the following steps:
and heating and melting the solid glue, then coating the solid glue on a cloth bag or a container, bonding the container and animal skin, standing and airing.
The beneficial effects are that: the solid glue provided by the application can soften to form non-Newtonian fluid after being heated, is extremely easy to bond after being coated on a cloth bag or a container, and can form solid glue after standing and airing.
Preferably, the heating temperature is 40 ℃.
The beneficial effects are that: the solid glue prepared by the application starts to melt into a liquid state when the heating temperature is 40 ℃, and the temperature is the temperature which can be born by animal skin, so that the animal skin is not scalded, and the animal body is not influenced by high temperature, thereby influencing the experimental result.
Compared with the prior art, the application has the following advantages and technical effects:
the solid glue provided by the application has the characteristics of simple components, convenience in manufacturing, good fixing effect, capability of being used by heating for multiple times, safety and innocuity for animals, no harm to animal skin, capability of being completely dissolved and eliminated by water, and capability of enabling experimental animals to carry out related experimental study again.
Drawings
The accompanying drawings, which are included to provide a further understanding of the application and are incorporated in and constitute a part of this specification, illustrate embodiments of the application and together with the description serve to explain the application. In the drawings:
FIG. 1 is a diagram showing the preparation process of example 1 of the present application;
FIG. 2 is a physical diagram of the solid glue obtained in example 1 of the present application;
FIG. 3 is a diagram showing an animal experiment of the solid gel obtained in example 1 of the present application.
Detailed Description
The following description of the embodiments of the present application will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present application, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.
In order that the above-recited objects, features and advantages of the present application will become more readily apparent, a more particular description of the application will be rendered by reference to the appended drawings and appended detailed description.
The solid glue for animal experiments comprises gelatin, zinc oxide and water as raw materials;
wherein, the mass ratio of the zinc oxide to the gelatin is 1:1, the adding amount of water is 1-2 times of the total mass of the zinc oxide and the gelatin.
In some preferred embodiments, the solid gum for animal experiments comprises the following raw materials in parts by weight: 100 parts of gelatin, 50-100 parts of zinc oxide and 200-400 parts of deionized water.
In a more preferred embodiment, the solid gel for animal experiments consists of the following raw materials in parts by weight: 100 parts of gelatin, 100 parts of zinc oxide and 200 parts of deionized water.
The preparation method of the solid gum for animal experiments comprises the following steps:
and mixing the raw materials to be pasty, heating and boiling in a water bath while stirring, and cooling to room temperature to obtain the solid glue.
The effect of the cooking is to melt the gelatin, which is convenient for mixing with zinc oxide and water, and the too low cooking temperature may result in incomplete liquefaction, and the too high cooking temperature or the cooking time may be that gelatin is carbonized and off-flavors are produced, so in some embodiments of the application, the cooking temperature is typically but not limited to 100 ℃ for 40 minutes.
The purpose of agitation, typically but not limiting of the choice of some embodiments of the application, is to accelerate gelatin liquefaction and ensure that it is mixed uniformly with the other ingredients, at a rate of 200r/min.
The application method of the solid glue for animal experiments comprises the following steps:
and heating and melting the solid glue, then coating the solid glue on a cloth bag or a container, bonding the container and animal skin, standing and airing.
In some preferred embodiments of the application, the heating temperature is 40 ℃.
The raw materials in the application are all purchased through a commercial way.
Example 1
The preparation method of the solid gum for animal experiments is shown in fig. 1, and comprises the following steps:
(1) Respectively weighing 100g of gelatin and 100g of zinc oxide, putting into a beaker, mixing and stirring, pouring into a milk pan, adding 200ml of deionized water, mixing and stirring to paste;
(2) Heating the milk pot in 100deg.C water bath, stirring at 200r/min, decocting for 40min until the milk pot is thick and can be drawn (shown in figure 2), and cooling to room temperature to obtain solid gel for animal experiment.
Example 2
The application method of the solid glue for animal experiments comprises the following steps:
the back of the rabbit or mouse was moistened with soapy water, after the hair on the back was shaved with a shaver, the solid gel obtained in example 1 was melted by heating to 40 ℃ and then applied to the back of the rabbit or mouse, and a cloth bag was attached (as shown in fig. 3).
The technical effects are as follows:
the effect of the solid glue of the application on adhering a cloth bag or container to an experimental animal is compared with that of a commercially available brothers ab glue or a carbofute ab glue as shown in table 1 below. Wherein, each performance detection standard is:
viscosity: 1900-2600 cps;
adhesive properties: the bonding strength is not less than 30MPa, and the shear strength is not less than 18MPa;
curing time: gluing within 3 minutes (room temperature) after mixing according to the mass ratio of A, B of 1:1, bonding under finger pressure, and solidifying within 3-30 minutes;
degree of allergy in animals: the skin rash is classified into mild, moderate and severe according to the area of the rash and the severity of itching
TABLE 1
As can be seen from Table 1, the solid gel obtained by the application has the characteristics of moderate hardness, strong cohesiveness and smooth coating, has no allergic phenomenon after being used on animal skin, is safe and nontoxic to animals, and can enable test animals to carry out multiple tests.
The present application is not limited to the above-mentioned embodiments, and any changes or substitutions that can be easily understood by those skilled in the art within the technical scope of the present application are intended to be included in the scope of the present application. Therefore, the protection scope of the present application should be subject to the protection scope of the claims.
Claims (8)
1. The solid glue for animal experiments is characterized in that the raw materials comprise gelatin, zinc oxide and water;
wherein, the mass ratio of the zinc oxide to the gelatin is 1:1, the adding amount of water is 1-2 times of the total mass of the zinc oxide and the gelatin.
2. The solid gel for animal experiments according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 100 parts of gelatin, 50-100 parts of zinc oxide and 200-400 parts of deionized water.
3. The solid gel for animal experiments according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 100 parts of gelatin, 100 parts of zinc oxide and 200 parts of deionized water.
4. The method for preparing the solid gel for animal experiments according to claim 1, which comprises the following steps:
and mixing the raw materials to be pasty, heating and boiling in a water bath while stirring, and cooling to room temperature to obtain the solid glue.
5. The method for preparing the solid gel for animal experiments according to claim 1, wherein the boiling temperature is 100 ℃ and the boiling time is 40min.
6. The method for preparing the solid gel for animal experiments according to claim 1, wherein the stirring rate is 200r/min.
7. The method of using a solid gel for animal experiments as claimed in claim 1, comprising the steps of:
and heating and melting the solid glue, then coating the solid glue on a container or animal skin, bonding the container and the animal skin, standing and airing.
8. The method of claim 7, wherein the heating temperature is 40 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310818148.5A CN116716082A (en) | 2023-07-05 | 2023-07-05 | Solid gum for animal experiments and preparation and use methods thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310818148.5A CN116716082A (en) | 2023-07-05 | 2023-07-05 | Solid gum for animal experiments and preparation and use methods thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116716082A true CN116716082A (en) | 2023-09-08 |
Family
ID=87864487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310818148.5A Pending CN116716082A (en) | 2023-07-05 | 2023-07-05 | Solid gum for animal experiments and preparation and use methods thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116716082A (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR944815A (en) * | 1947-03-25 | 1949-04-15 | Cold liquid glue obtained by treating gelatin with an acid followed by neutralization | |
| CN101503612A (en) * | 2009-03-10 | 2009-08-12 | 南京航空航天大学 | Solvent type repair adhesive special for ancient Chinese ink cultural relics and preparation thereof |
| CN102690628A (en) * | 2012-05-25 | 2012-09-26 | 太仓市新星轻工助剂厂 | Environmental protection bottleneck sealing glue and preparation method thereof |
| CN112640810A (en) * | 2021-01-01 | 2021-04-13 | 中国农业科学院兰州兽医研究所 | Device for keeping reptile parasites on surface of animal experiment and equipment |
| CN217722385U (en) * | 2021-01-01 | 2022-11-04 | 中国农业科学院兰州兽医研究所 | Device for keeping reptile parasites on surface of animal experiment |
| CN115850723A (en) * | 2022-12-15 | 2023-03-28 | 无锡市兰翔胶业有限公司 | Gelatin material for changing water content of rubber roller |
| CN115887732A (en) * | 2022-12-23 | 2023-04-04 | 稳得希林(沈阳)生物科技有限公司 | Medical gelatin dressing and preparation method thereof |
-
2023
- 2023-07-05 CN CN202310818148.5A patent/CN116716082A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR944815A (en) * | 1947-03-25 | 1949-04-15 | Cold liquid glue obtained by treating gelatin with an acid followed by neutralization | |
| CN101503612A (en) * | 2009-03-10 | 2009-08-12 | 南京航空航天大学 | Solvent type repair adhesive special for ancient Chinese ink cultural relics and preparation thereof |
| CN102690628A (en) * | 2012-05-25 | 2012-09-26 | 太仓市新星轻工助剂厂 | Environmental protection bottleneck sealing glue and preparation method thereof |
| CN112640810A (en) * | 2021-01-01 | 2021-04-13 | 中国农业科学院兰州兽医研究所 | Device for keeping reptile parasites on surface of animal experiment and equipment |
| CN217722385U (en) * | 2021-01-01 | 2022-11-04 | 中国农业科学院兰州兽医研究所 | Device for keeping reptile parasites on surface of animal experiment |
| CN115850723A (en) * | 2022-12-15 | 2023-03-28 | 无锡市兰翔胶业有限公司 | Gelatin material for changing water content of rubber roller |
| CN115887732A (en) * | 2022-12-23 | 2023-04-04 | 稳得希林(沈阳)生物科技有限公司 | Medical gelatin dressing and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| 刘振沛编: "《纺织工业中的表面活性剂》", vol. 2, 30 September 1993, 测绘出版社出版, pages: 148 * |
| 刘文: "《药用高分子材料学》", vol. 2, 30 June 2017, 中国中医药出版社, pages: 98 * |
| 强亮生等: "《精细化工综合实验》", vol. 7, 31 July 2015, 哈尔滨工业大学出版社, pages: 104 * |
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