CN116570817B - Magnetic drive catheter with variable rigidity - Google Patents

Magnetic drive catheter with variable rigidity Download PDF

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Publication number
CN116570817B
CN116570817B CN202310851961.2A CN202310851961A CN116570817B CN 116570817 B CN116570817 B CN 116570817B CN 202310851961 A CN202310851961 A CN 202310851961A CN 116570817 B CN116570817 B CN 116570817B
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China
Prior art keywords
magnetic
tube
hollow
main body
catheter
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CN202310851961.2A
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CN116570817A (en
Inventor
徐海峰
刘源
黄静
刘祥超
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Shenzhen Institute of Advanced Technology of CAS
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Shenzhen Institute of Advanced Technology of CAS
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Priority to CN202310851961.2A priority Critical patent/CN116570817B/en
Publication of CN116570817A publication Critical patent/CN116570817A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0074Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M2025/0063Catheters; Hollow probes characterised by structural features having means, e.g. stylets, mandrils, rods or wires to reinforce or adjust temporarily the stiffness, column strength or pushability of catheters which are already inserted into the human body

Abstract

The application discloses a magnetic drive catheter with variable rigidity, and relates to the technical field of medical appliances. Not only increases the steering flexibility of the catheter, but also ensures that the overall maximum rigidity can meet the requirements of operations such as advancing, sampling and the like, and improves the steering flexibility and the operability of the catheter. The magnetic drive catheter with variable rigidity comprises a main body hard tube, a hollow hose, a limiting tube and a magnetic piece which are sequentially arranged along the axial direction; a magnetic spiral tube is sleeved on the main body hard tube; the inner diameter and the outer diameter of the main hard tube and the hollow soft tube are equal; the inner diameter of the limiting pipe is equal to the inner diameter of the main hard pipe, and the outer diameter of the limiting pipe is larger than the inner diameter of the magnetic spiral pipe; the main body hard tube, the hollow hose and the limiting tube are all processed by soft materials, and the rigidity of the main body hard tube, the rigidity of the limiting tube and the rigidity of the magnetic piece are all larger than those of the hollow hose; the magnetic spiral tube can be spirally advanced or retreated on the surfaces of the main body hard tube and the hollow hose. The application is used for improving the performance of the catheter.

Description

Magnetic drive catheter with variable rigidity
Technical Field
The application relates to the technical field of medical instruments, in particular to a magnetic drive catheter with variable rigidity.
Background
Catheters have found widespread use in minimally invasive surgery, but due to the high stiffness and uniform overall stiffness of conventional catheters, the magnitude of bending is limited and cannot pass through the corners that are biased to be larger. That is, conventional catheters do not achieve a perfect unity of stiffness and compliance. Conventional catheters have some stiffness to ensure distance traveled by the catheter during passage through an elongated passageway such as a blood vessel, and thus lose some flexibility and flexibility, and are not steerable when encountering large angled corners, such as those approaching 90 °. Similarly, in the case of in vivo sampling using a conventional catheter, it is difficult to achieve the conventional catheter if the sampling site is located farther from the linear path region of the catheter guidewire. This results in the need to open multiple wounds in minimally invasive surgery, if there are more sites to detect or do the surgery, i.e., increasing the pain of the patient and also defeating the purpose underlying the minimally invasive surgery. These all reflect the many inconveniences of conventional catheter guidewires in use.
In order to overcome the defects of single rigidity of the traditional catheter in use, the flexibility and operability of the catheter are increased.
Disclosure of Invention
The embodiment of the application provides a magnetic drive catheter with variable rigidity, which not only increases the steering flexibility of the catheter, but also ensures that the overall maximum rigidity can meet the requirements of operations such as advancing, sampling and the like, and further improves the steering flexibility and the operability of the catheter.
In order to achieve the above object, an embodiment of the present application provides a magnetic drive catheter with variable rigidity, including a main hard tube, a hollow hose, a limiting tube and a magnetic member sequentially arranged along an axial direction; a magnetic spiral tube is sleeved on the main body hard tube; the inner diameter and the outer diameter of the main hard tube and the hollow soft tube are equal; the inner diameter of the limiting pipe is equal to the inner diameter of the main hard pipe, and the outer diameter of the limiting pipe is larger than the inner diameter of the magnetic spiral pipe; the main body hard tube, the hollow hose and the limiting tube are all processed by soft materials, and the rigidity of the main body hard tube, the rigidity of the limiting tube and the rigidity of the magnetic piece are all larger than those of the hollow hose; the magnetic spiral tube can be spirally advanced or retreated on the surfaces of the main body hard tube and the hollow hose.
Further, the main body hard pipe is in sticky connection with the hollow hose; the limiting pipe is in sticky connection with the hollow hose and the magnetic piece.
Further, the hollow hose is bendable relative to the main body wand.
Further, the rigidity of the hollow hose is 0.2-0.5 times that of the main body hard tube.
Further, the magnetic piece is driven by an external magnetic control system, so that deflection in any direction can be realized
Further, the surfaces of the main body hard tube and the hollow hose are respectively provided with an anti-slip protrusion or a spiral channel.
Further, the magnetic piece is a magnetic hollow tube; the inner diameter and the outer diameter of the magnetic hollow tube are equal to those of the main hard tube; the magnetic hollow tube is also processed by adopting a soft material.
Further, the magnetic piece is a magnetic steel needle; the inner diameter and the outer diameter of the magnetic steel needle are equal to those of the main body hard tube; the magnetic steel needle is a metal needle tube which is enough to penetrate biological tissues.
Further, the magnetic drive conduit with variable rigidity further comprises an additional deformation section; the additional deformation section comprises an additional magnetic hollow tube, an additional limiting tube and an additional soft hollow tube; the two ends of the additional limiting pipe are respectively connected with an additional hollow hose and an additional magnetic hollow pipe in an adhesive manner; the additional hollow hose is adhered and connected with the magnetic hollow tube; the specification and the material of the added hollow hose are the same as those of the hollow hose; the specification and the material of the additionally arranged limiting pipe are the same as those of the limiting pipe, and the specification and the material of the additionally arranged magnetic hollow pipe are the same as those of the magnetic hollow pipe.
Compared with the prior art, the application has the following beneficial effects:
1. according to the magnetic drive catheter with variable rigidity, the hollow hose with lower rigidity is added on the main body hard tube, so that the whole catheter is easy to bend at the part of the hollow hose. The bending of the hollow hose portion when facing a large angle corner or obstruction can help the head of the catheter bypass the obstruction, thereby driving the catheter entirely through the obstruction, enhancing steering flexibility of the catheter.
2. According to the magnetic drive catheter with variable rigidity, the magnetic spiral tube is sleeved on the main body hard tube, when the catheter passes through and reaches a designated position, and the catheter is supported by certain rigidity to complete certain actions, the magnetic spiral tube can move to the outside of the hollow hose to restrain bending of the hollow hose, so that the rigidity of the whole catheter is increased, and then required rigid operation is completed.
3. According to the variable-rigidity magnetic drive catheter, the magnetic hollow tube is added at the front end of the catheter, and when the variable-rigidity magnetic drive catheter works, the magnetic hollow tube and the magnetic spiral tube are driven to move through the external magnetic control system, so that the advancing direction of the catheter is controlled, and the steering operability of the catheter in a body is enhanced.
4. The variable-rigidity magnetic drive catheter is characterized in that the front end of the catheter is provided with the additional deformation section, and the relative position of the magnetic spiral tube on the catheter is adjusted to realize that only the front section of the magnetic hollow tube is driven to turn by a magnetic field or the magnetic hollow tube and the additional magnetic hollow tube in the additional deformation section are driven to turn by the magnetic field together, so that the flexibility is greatly enhanced, and the variable-rigidity magnetic drive catheter can adapt to more complex internal cavity environments.
5. Compared with the traditional catheter which controls the trend and action of the catheter by means of fine operations such as pushing, pulling, twisting and the like, the magnetic drive catheter with variable rigidity can be more accurately and simply controlled in a magnetic drive mode, and the requirements on operators are reduced.
Drawings
In order to more clearly illustrate the embodiments of the application or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the application, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic structural diagram of embodiment 1 of the present application;
FIG. 2 is a schematic diagram of the bending deformation of example 1 of the present application in operation;
FIG. 3 is a schematic structural diagram of embodiment 2 of the present application;
fig. 4 is a schematic structural diagram of embodiment 3 of the present application.
Description of the embodiments
The following description of the embodiments of the present application will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present application, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.
In the description of the present application, it should be understood that the terms "center," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like indicate orientations or positional relationships based on the orientation or positional relationships shown in the drawings, merely to facilitate describing the present application and simplify the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present application.
In the description of the present application, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; the specific meaning of the above terms in the present application will be understood in specific cases by those of ordinary skill in the art.
The terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more such feature. In the description of the present application, unless otherwise indicated, the meaning of "a plurality" is two or more.
Examples
Referring to fig. 1 and 2, an embodiment of the present application provides a variable stiffness magnetic drive catheter, which includes a main body hard tube 1, a hollow hose 2, a stopper tube 3, a magnetic hollow tube 4, and a magnetic spiral tube 5. Wherein main body hard tube 1, hollow hose 2, spacing pipe 3 and magnetism hollow tube 4 concatenate in proper order along the axial, and magnetism spiral pipe 5 cover is established on main body hard tube 1 or hollow hose 2, and magnetism spiral pipe 5 can go forward or retreat on the surface of main body hard tube 1 and hollow hose 2 spiral.
In particular, since the soft material has a good lubricity, it is possible to ensure that the guide wire passes inside with low resistance. Therefore, the main body hard tube 1, the hollow hose 2, the limiting tube 3 and the magnetic hollow tube 4 are all processed by soft materials, and the rigidity of the main body hard tube 1, the limiting tube 3 and the magnetic hollow tube 4 is larger than that of the hollow hose 2. Specifically, the rigidity of the main body hard tube 1, the limit tube 3 and the magnetic hollow tube 4 can be relatively close. The rigidity of the hollow hose 2 must be significantly lower than the rigidity of the main body hard tube 1, the stopper tube 3 and the magnetic hollow tube 4. For example: the rigidity of the main body hard tube 1, the spacing tube 3 and the magnetic hollow tube 4 is 5GPa, while the rigidity of the soft hollow tube is 1GPa. Thereby, the hollow hose 2 can be bent with respect to the main body hard tube 1. The magnetic hollow tube 4 is driven by an external magnetic control system, so that deflection in any direction can be realized. It should be noted that the external magnetic control system is in the prior art, and will not be described in detail here.
The main body hard tube 1 is connected with the hollow hose 2 in an adhesive mode, and the limiting tube 3 is connected with the hollow hose 2 and the magnetic hollow tube 4 in an adhesive mode through glue, so that smooth transition is achieved after the connection is processed.
In order to facilitate the movement of the catheter and the threading of the guide wire, the inner diameters of the main hard tube 1, the hollow hose 2, the magnetic hollow tube 4 and the limiting tube 3 are equal, and the outer diameters of the main hard tube 1, the hollow hose 2 and the magnetic hollow tube 4 are also equal.
In addition, in order to prevent the magnetic coil 5 from coming out of the entire guide tube when it is advanced, the outer diameter of the stopper tube 3 is larger than the inner diameter of the magnetic coil 5. Thereby, the magnetic coil 5 will not advance any further when it moves into contact with the stopper tube 3.
The magnetic spiral tube 5 is in clearance fit with the main body hard tube 1 and the hollow hose 2, and in order to ensure that the magnetic spiral does not slip when the surfaces of the main body hard tube 1 and the hollow hose 2 are screwed in, anti-slip protrusions can be arranged on the surfaces of the main body hard tube 1 and the hollow hose 2, or spiral channels are engraved on the surfaces.
The working principle of example 1 is as follows:
when the catheter of example 1 is walked around the body cavity or duct, the initial position of the magnetic coil 5 is on the surface of the main body hard tube 1, i.e., not with the hollow hose 23. The magnetic hollow tube 4 is acted by a magnetic field generated by an external magnetic control system, has a guiding function on the whole conduit, and the hollow hose 2 is not limited, so that the conduit has good trafficability.
When the catheter encounters a disorder in a living body and needs to turn, the advancing direction of the magnetic hollow tube 4 is adjusted through the external magnetic drive system, so that the magnetic hollow tube 4 passes through the disorder, and the whole catheter can be guided to pass through the disorder by matching with the advancing movement of the main body hard tube 1.
When the catheter encounters an uneven channel surface, the head of the guide wire in the catheter is coarser than the surface of the main hard tube 1 due to more devices, and the density of the head is higher, so that the guide wire is easy to be clamped at an uneven part. At this time, if the main body hard tube 1 is further advanced, the guide wire in the catheter is easily wound around the uneven portion. At this time, it is necessary to drive the magnetic spiral tube 5 by an external magnetic driving system to be screwed into and cover the hollow hose 2, thereby enhancing the rigidity of the catheter head. Then, the main body hard tube 1 is advanced continuously, and the catheter can be advanced continuously at the uneven portion.
When sampling operation is needed, a rotating magnetic field is applied to the magnetic spiral tube 5 through an external magnetic drive system, the magnetic spiral tube 5 rotates under the action of magnetic force, and meanwhile, because spiral contact is formed between the magnetic spiral tube 5 and the main body hard tube 1 and the hollow hose 2, the magnetic spiral tube is screwed in along the axial direction of the catheter under the action of friction force and moves towards the direction of the hollow hose 2 under the drive of the rotating magnetic field; the more the magnetic spiral pipe 5 is overlapped with the hollow hose 2, the stronger the restraint on the hollow hose 2 is, the higher the rigidity of the whole catheter is; when the required stiffness is reached, the magnetic coil 5 stops precession and the operator operates the catheter and guidewire to complete the sampling.
In summary, the whole structure of the application takes a hard hollow pipe as a main body, the front end of the main body hard pipe 1 is connected with a hollow hose 2, the front end of the hollow hose 2 is connected with a limit sleeve, the front end of the limit sleeve is connected with a magnetic hollow pipe 4, and a magnetic spiral pipe 5 is sleeved outside the guide pipe.
Due to the presence of the hollow hose 2, the whole of the catheter is easily bent at the portion of the hollow hose 2. The bending of the hollow hose 2 portion in the face of a large angle corner or obstruction can help the head of the catheter guidewire bypass the obstruction, thereby driving the catheter entirely through the obstruction, which greatly enhances the steering flexibility of the overall catheter. When the catheter passes through and reaches a designated position, and some rigidity is needed to support the catheter to perform some actions, the magnetic spiral tube 5 can move to the position of the hollow hose 2 to restrain the bending of the hollow hose 2, so that the rigidity of the whole catheter is increased, and the required rigidity operation is finished.
In the aspect of control, unlike the traditional catheter guide wire which controls the trend and action of the catheter by means of fine operations such as push-pull, torsion and the like, the application can realize the control of the catheter more accurately and simply by means of magnetic driving. The control methods of conventional catheters are mostly control skills that a doctor has fuelled during practice, for which the doctor needs a lot of time and practice in obtaining the skills, on the one hand, and when the doctor teaches the control skills, on the other hand, since the skills are personal and intelligible, the learner still needs to spend enough time to comprehend and master the skills. In the application, because the direct control catheter is the magnetic field excited by the magnetic drive system, an operator can operate the catheter by only learning a simple control panel or software of the magnetic drive system, thus greatly reducing the learning and operation burden of doctors.
Examples
Referring to fig. 3, embodiment 2 differs from embodiment 1 only in that: the magnetic hollow tube 4 in example 1 was replaced with a magnetic steel needle 6. The magnetic steel needle 6 is equal to the inner diameter and the outer diameter of the main hard tube 1, and the magnetic steel needle 6 is a metal needle tube which is enough to penetrate biological tissues. Thus, example 2 can enhance the handling ability of the catheter itself to tissue.
The working principle of the embodiment 2 of the application is as follows:
when the catheter of example 2 is moved around the body cavity or the duct, the initial position of the magnetic spiral 5 is on the surface of the main body hard tube 1, i.e., not in contact with the hollow hose 2, when the catheter of example 1 is moved around the body cavity or the duct. The magnetic hollow tube 4 is acted by a magnetic field generated by an external magnetic control system, has a guiding function on the whole conduit, and the hollow hose 2 is not limited, so that the conduit has good trafficability.
When the catheter encounters a disorder in a living body and needs to turn, the advancing direction of the magnetic steel needle 6 is adjusted through the external magnetic drive system, so that the magnetic steel needle 6 passes through the disorder, and the whole catheter can be guided to pass through the disorder by matching with the advancing movement of the main body hard tube 1.
When the catheter encounters an uneven channel surface, the head of the guide wire in the catheter is coarser than the surface of the main hard tube 1 due to more devices, and the density of the head is higher, so that the guide wire is easy to be clamped at an uneven part. At this time, if the main body hard tube 1 is further advanced, the guide wire in the catheter is easily wound around the uneven portion. At this time, it is necessary to drive the magnetic spiral tube 5 by an external magnetic driving system to be screwed into and cover the hollow hose 2, thereby enhancing the rigidity of the catheter head. Then, the main body hard tube 1 is advanced continuously, and the catheter can be advanced continuously at the uneven portion.
Example 2 can puncture diseased tissue in the lumen. Compared with the embodiment 1, the embodiment 2 uses the guide wire to puncture the tissue, and the embodiment 2 uses the self magnetic steel needle 6 to puncture the tissue directly, so that the efficiency of damaging the lesion tissue is higher. Example 2 before moving to the lesion tissue, the magnetic spiral tube 5 is driven by a magnetic field to be screwed forward to cover the hollow hose 2, so that the rigidity of the whole catheter is enhanced, and then the catheter is operated to puncture the lesion tissue. Since the magnetic steel needle 6 itself has magnetism, the target tissue can be aligned by controlling the direction by the magnetic field. In addition, if the magnetism of the magnetic steel needle 6 needs to be improved, a strong magnetic material can be plated on the surface of the magnetic steel needle, or a sleeve made of the strong magnetic material can be nested.
Examples
Referring to fig. 4, embodiment 3 differs from embodiment 1 only in that: embodiment 3 further comprises adding a deformation section. Specifically, the additional deformation section comprises an additional hollow hose 7, an additional limiting pipe 8 and an additional magnetic hollow pipe 9. The two ends of the additional limiting pipe 8 are respectively and adhesively connected with the additional hollow hose 7 and the additional magnetic hollow pipe 9, and the additional hollow hose 7 is adhesively connected with the magnetic hollow pipe 4. The specification and the materials of the additional hollow hose 7 and the hollow hose 2 are the same; the specification and the material of the added limiting pipe 8 are the same as those of the limiting pipe 3, and the specification and the material of the added magnetic hollow pipe 9 and the magnetic hollow pipe 4 are the same. Thus, example 3 contains two deformed segments, and has higher degrees of freedom and flexibility.
The working principle of example 3 is as follows:
the movement of example 3 is similar to that of example 1, and example 3 also relies on the pulling torsion of the main body hard tube 1 and the external magnetic field to drive the magnetic spiral tube 5 to control the movement, which is different in that example 3 has two flexible sections, thus having stronger deformability, more movement modes and better environmental adaptability. Specifically, embodiment 3 has two sections of magnetic hollow tubes 4, and by adjusting the relative positions of the magnetic spiral tubes 5 on the catheter, only the front section of magnetic hollow tube 4 can be driven to turn by the magnetic field, or the magnetic hollow tube 4 and the additional magnetic hollow tube 9 can be driven to turn by the magnetic field. By this way of adjustment, the flexibility of example 3 is greatly enhanced, enabling adaptation to more complex in vivo luminal tract environments.
The present application is not limited to the above embodiments, and any changes or substitutions within the technical scope of the present application should be covered by the scope of the present application. Therefore, the protection scope of the present application should be subject to the protection scope of the claims.

Claims (7)

1. The magnetic drive catheter with variable rigidity is characterized by comprising a main body hard tube, a hollow hose, a limiting tube and a magnetic piece which are sequentially arranged along the axial direction; a magnetic spiral tube is sleeved on the main body hard tube; the inner diameter and the outer diameter of the main hard tube and the hollow soft tube are equal; the inner diameter of the limiting pipe is equal to the inner diameter of the main hard pipe, and the outer diameter of the limiting pipe is larger than the inner diameter of the magnetic spiral pipe; the main body hard tube, the hollow hose and the limiting tube are all processed by soft materials, and the rigidity of the main body hard tube, the rigidity of the limiting tube and the rigidity of the magnetic piece are all larger than those of the hollow hose; the magnetic spiral pipe can spirally advance or retreat on the surfaces of the main body hard pipe and the hollow hose; the hollow hose being bendable relative to the main body wand; the magnetic piece is driven by an external magnetic control system to realize deflection in any direction; the surfaces of the main body hard tube and the hollow hose are respectively provided with an anti-slip protrusion or a spiral channel.
2. The variable stiffness magnetic drive conduit of claim 1 wherein the main body rigid tube is adhesively connected to the hollow hose; the limiting pipe is in sticky connection with the hollow hose and the magnetic piece.
3. The variable stiffness magnetic drive catheter of claim 1, wherein the stiffness of the hollow hose is 0.2-0.5 times the stiffness of the main body hard tube.
4. The variable stiffness magnetic drive catheter of claim 1, wherein the magnetic element is a magnetic hollow tube; the inner diameter and the outer diameter of the magnetic hollow tube are equal to those of the main hard tube; the magnetic hollow tube is also processed by adopting a soft material.
5. The variable stiffness magnetic drive catheter of claim 4 wherein the magnetic hollow tube is fabricated from a hybrid magnetic material and an elastic material.
6. The variable stiffness magnetic drive catheter of claim 1, wherein the magnetic element is a magnetic steel needle; the inner diameter and the outer diameter of the magnetic steel needle are equal to those of the main body hard tube; the magnetic steel needle is a metal needle tube capable of penetrating biological tissues.
7. The variable stiffness magnetically driven catheter of claim 4, comprising an additional deformation section; the additional deformation section comprises an additional magnetic hollow pipe, an additional limiting pipe and an additional hollow hose; the two ends of the additional limiting pipe are respectively connected with an additional hollow hose and an additional magnetic hollow pipe in an adhesive manner; the additional hollow hose is adhered and connected with the magnetic hollow tube; the specification and the material of the added hollow hose are the same as those of the hollow hose; the specification and the material of the additionally arranged limiting pipe are the same as those of the limiting pipe, and the specification and the material of the additionally arranged magnetic hollow pipe are the same as those of the magnetic hollow pipe.
CN202310851961.2A 2023-07-12 2023-07-12 Magnetic drive catheter with variable rigidity Active CN116570817B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5833604A (en) * 1993-07-30 1998-11-10 E.P. Technologies, Inc. Variable stiffness electrophysiology catheter
CN102711585A (en) * 2009-11-02 2012-10-03 波士顿科学国际医疗贸易公司 Flexible endoscope with modifiable stiffness

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9370639B2 (en) * 2013-03-12 2016-06-21 Cook Medical Technologies, LLC Variable stiffness catheter
EP3787603A4 (en) * 2018-05-03 2022-04-20 Bionaut Labs Ltd. Methods and apparatus for deployment and retraction of functional small particles in living tissues

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5833604A (en) * 1993-07-30 1998-11-10 E.P. Technologies, Inc. Variable stiffness electrophysiology catheter
CN102711585A (en) * 2009-11-02 2012-10-03 波士顿科学国际医疗贸易公司 Flexible endoscope with modifiable stiffness

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