CN116441066B

CN116441066B - Bovine serum collection system based on intelligent separation

Info

Publication number: CN116441066B
Application number: CN202310700056.7A
Authority: CN
Inventors: 陆豪杰; 严正龙; 马东; 施钲罡; 叶军
Original assignee: Suzhou Shuangru Biotechnology Co ltd
Current assignee: Suzhou Shuangru Biotechnology Co ltd
Priority date: 2023-06-14
Filing date: 2023-06-14
Publication date: 2023-11-14
Anticipated expiration: 2043-06-14
Also published as: CN116441066A

Abstract

The invention relates to the technical field of bovine serum separation and collection, in particular to a bovine serum collection system based on intelligent separation, which comprises the following components: the bovine blood conveying module is used for conveying the collected bovine blood into the corresponding container; the separation module comprises a centrifugal unit used for separating the bovine blood and a centrifugal motor connected with the centrifugal unit and used for providing centrifugal rotation power; the extraction module is used for extracting the bovine serum separated by the separation module and comprises a grabbing mechanical arm arranged above the centrifugal unit, an extraction chamber arranged below the grabbing mechanical arm for providing a serum extraction place and an extraction assembly partially arranged above the extraction chamber for extracting the bovine serum; the central control module is used for adjusting the inclination angle of the test tube to a first corresponding inclination angle according to the average increment of the temperature of the test tube in the unit period. The invention realizes the improvement of serum collection accuracy and stability.

Description

Bovine serum collection system based on intelligent separation

Technical Field

The invention relates to the technical field of bovine serum separation and collection, in particular to a bovine serum collection system based on intelligent separation.

Background

In the prior art, a bovine serum collection system is mainly divided into two parts, wherein one part is used for collecting blood, the other part is used for separating or precipitating serum from the blood, a common serum separation technical means is that a centrifugal machine or natural precipitation is adopted, but the separation of the centrifugal machine has the problem that the temperature in the centrifugal machine is increased to influence the serum collection stability.

Chinese patent publication No.: CN115382251a discloses a raw material collecting device for separating and extracting bovine serum, which belongs to the technical field of bovine serum collection, and comprises a base, a vertical plate, a blood containing component, a stirring component and a driving component, wherein the vertical plate is fixedly arranged on one side of the base and is used for supporting the driving component, the blood containing component is arranged on one side of the vertical plate and is controlled by the driving component to swing reciprocally, the stirring component is movably arranged inside the blood containing component, and in the reciprocal swinging process of the blood containing component, the stirring component moves inside the blood containing component so as to stir and centrifuge the bovine blood inside the blood containing component; therefore, the raw material collecting device for separating and extracting the bovine serum has the problem that the temperature of the test tube is increased due to heat generated in the separation process, so that the accuracy and the stability of serum collection are influenced.

Disclosure of Invention

Therefore, the invention provides a bovine serum collection system based on intelligent separation, which is used for solving the problem that the temperature of a test tube is increased due to heat generated in the separation process in the prior art to influence the serum collection accuracy and stability.

In order to achieve the above object, the present invention provides a bovine serum collection system based on intelligent separation, comprising: the bovine blood conveying module is used for conveying the collected bovine blood into the corresponding container; the separation module is connected with the bovine blood conveying module and comprises a centrifugal unit for separating bovine blood and a centrifugal motor which is connected with the centrifugal unit and is used for providing centrifugal rotation power, wherein an angle adjusting component for adjusting the inclination angle of the test tube and the test tube which is movably connected with the angle adjusting component and is used for placing bovine blood are arranged in the centrifugal unit; the extraction module is connected with the separation module and used for extracting the bovine serum separated by the separation module, and comprises a grabbing mechanical arm arranged above the centrifugal unit, an extraction chamber arranged below the grabbing mechanical arm and used for providing a serum extraction place, and an extraction assembly partially arranged above the extraction chamber and used for extracting the bovine serum, wherein a visual detector used for detecting the volume of the centrifuged serum and a weight sensor arranged below the visual detector and used for detecting the weight of a test tube in the extraction chamber are arranged on the side wall inside the extraction chamber; the central control module is respectively connected with the bovine blood conveying module, the separation module and the extraction module and is used for adjusting the inclination angle of the test tube to a first corresponding inclination angle according to the average increment of the temperature of the test tube in a unit period, adjusting the rotating speed of the centrifugal motor to the first corresponding rotating speed according to the volume ratio of serum separated from the test tube in the extraction chamber, secondarily adjusting the rotating speed of the centrifugal motor to a second corresponding rotating speed according to the variance of the weight variation of the test tube, and secondarily adjusting the inclination angle of the test tube to the second corresponding inclination angle according to the variance of the weight variation of the secondarily detected test tube when the secondary adjustment of the rotating speed of the centrifugal motor is completed.

Further, the central control module controls a temperature sensor arranged on the side wall of the test tube in the centrifugal unit to detect the temperature of the test tube at the beginning and the end of a single period, calculates the average increment of the temperature of the test tube in a unit period according to the test tube temperature detection result, and determines three judging modes whether the separation stability is within an allowable range according to the average increment of the temperature of the test tube in the unit period,

the first type of judgment mode is that the central control module judges that the separation stability is within an allowable range under a preset first temperature condition;

the second type of judgment mode is that the central control module judges that the separation stability is lower than the allowable range under the condition of a preset second temperature, and adjusts the inclination angle of the test tube to a corresponding inclination angle by calculating the difference value between the average increment of the temperature of the test tube and the preset first temperature;

the third type of judgment mode is that the central control module preliminarily judges that the bovine blood sedimentation degree is lower than the allowable range under the preset third temperature condition, and calculates the volume ratio of serum separated from a test tube in the extraction chamber so as to secondarily judge whether the bovine blood sedimentation degree is in the allowable range;

the preset first temperature condition is that the average increment of the temperature of the test tube is smaller than or equal to the preset first temperature; the preset second temperature condition is that the average increment of the temperature of the test tube is larger than the preset first temperature and smaller than or equal to the preset second temperature; the preset third temperature condition is that the average increment of the test tube temperature is larger than the preset second temperature;

Wherein the preset first temperature is less than the preset second temperature.

Further, the central control module determines three types of adjustment modes aiming at the inclination angle of the test tube according to the difference value between the average increment of the test tube temperature and the preset first temperature under the preset second temperature condition, wherein,

the first type of adjustment mode is that the central control module adjusts the inclination angle of the test tube to a preset inclination angle under the condition of a preset first temperature difference value;

the second type of adjustment mode is that the central control module adjusts the inclination angle of the test tube to the first inclination angle by using a preset second inclination angle adjustment coefficient under the condition of a preset second temperature difference value;

the third type of adjustment mode is that the central control module adjusts the inclination angle of the test tube to a second inclination angle by using a preset first inclination angle adjustment coefficient under the condition of presetting a third temperature difference value;

the preset first temperature difference condition is that the difference between the average increment of the test tube temperature and the preset first temperature is smaller than or equal to the preset first temperature difference, and the preset second temperature difference condition is that the difference between the average increment of the test tube temperature and the preset first temperature is larger than the preset first temperature difference and smaller than or equal to the preset second temperature difference; the preset third temperature difference condition is that the difference between the average increment of the test tube temperature and the preset first temperature is larger than the preset second temperature difference;

The preset first temperature difference value is smaller than the preset second temperature difference value, and the preset first inclination angle adjusting coefficient is smaller than the preset second inclination angle adjusting coefficient.

Further, the central control module determines whether the bovine blood sedimentation degree is in three secondary judgment modes of an allowable range according to the volume ratio of the serum separated from the test tube detected and calculated by the visual detector under the preset third temperature condition, wherein,

the first secondary judgment mode is that the central control module judges that equipment faults exist in the centrifugal module under the condition of preset first volume ratio and sends out equipment fault maintenance notification aiming at the centrifugal module;

the second secondary judgment mode is that the central control module secondarily judges that the bovine blood sedimentation degree is lower than the allowable range under the condition of a preset second volume ratio, and the rotating speed of the centrifugal motor is regulated to a corresponding rotating speed by calculating the difference value between the volume ratio of serum separated from the test tube and the preset first volume ratio;

the third type of secondary judgment mode is that the central control module secondarily judges that the bovine blood sedimentation degree is in an allowable range under the condition of presetting a third volume ratio;

the preset first volume ratio is that the volume ratio of serum separated from the test tube is smaller than or equal to the preset first volume ratio; the preset second volume ratio is that the volume ratio of serum separated from the test tube is larger than the preset first volume ratio and smaller than or equal to the preset second volume ratio; the preset second volume ratio is that the volume ratio of serum separated from the test tube is larger than the preset second volume ratio;

Wherein the predetermined first volume fraction is less than the predetermined second volume fraction.

Further, the central control module determines three types of adjustment modes for the rotating speed of the centrifugal motor according to the difference value between the volume ratio of the serum separated from the test tube and the preset first volume ratio under the condition of the preset second volume ratio,

the first type of rotation speed adjusting mode is that the central control module adjusts the rotation speed of the centrifugal motor to the rotation speed of the preset centrifugal motor under the condition of a preset first volume ratio difference value;

the second type of rotation speed adjusting mode is that the central control module adjusts the rotation speed of the centrifugal motor to a first rotation speed by using a preset first rotation speed adjusting coefficient under the condition of a preset second volume ratio difference value;

the third type of rotation speed adjusting mode is that the central control module adjusts the rotation speed of the centrifugal motor to a second rotation speed by using a preset second rotation speed adjusting coefficient under the condition of presetting a third volume ratio difference value;

the preset first volume ratio difference condition is that the difference between the volume ratio of serum separated from the test tube and the preset first volume ratio is smaller than or equal to the preset first volume ratio difference; the preset second volume ratio difference condition is that the difference between the volume ratio of serum separated from the test tube and the preset first volume ratio is larger than the preset first volume ratio difference and smaller than or equal to the preset second volume ratio difference; the preset third volume ratio difference condition is that the difference between the volume ratio of serum separated from the test tube and the preset first volume ratio is larger than the preset second volume ratio difference;

The preset first volume ratio difference is smaller than the preset second volume ratio difference, and the preset first rotating speed adjustment coefficient is smaller than the preset second rotating speed adjustment coefficient.

Further, the central control module controls the weight sensor to detect the weight of the separated test tubes one by one in the extracting chamber to obtain the weight of the separated test tubes, calculates the weight variation of the single test tubes according to the weight of the separated single test tubes and the initial weight of the single test tubes, calculates the weight variation variance of the test tubes according to the weight variation of a plurality of single test tubes, and determines whether the moisture volatilization degree is within the allowable range according to the weight variation variance of the test tubes,

the first type of volatilization degree judging mode is that the central control module judges that the moisture volatilization degree is in an allowable range under the condition of a preset first variance;

the second type of volatilization degree judging mode is that the central control module judges that the water volatilization degree exceeds the allowable range under the condition of a preset second variance, and the rotating speed of the centrifugal motor is secondarily regulated to a second corresponding rotating speed by calculating the difference value between the variance of the weight variation of the test tube and the preset first variance;

The third type of volatilization degree judging mode is that the central control module judges that the moisture volatilization degree exceeds the allowable range under the condition of a preset third difference, judges that the centrifugal module has equipment faults and sends out equipment fault maintenance notification aiming at the centrifugal module;

the preset first variance condition is that the variance of the weight variation of the test tube is smaller than or equal to the preset first variance; the preset second variance condition is that the variance of the weight variation of the test tube is larger than the preset first variance and smaller than or equal to the preset second variance; the preset third variance condition is that the variance of the weight variation of the test tube is larger than the preset second variance;

wherein the preset first variance is smaller than the preset second variance.

Further, the central control module determines three secondary adjustment modes for the rotating speed of the centrifugal motor according to the difference value between the variance of the weight variation of the test tube and the preset first variance under the condition of the preset second variance, wherein,

the first-class rotating speed secondary adjusting mode is that the central control module secondarily adjusts the rotating speed of the centrifugal motor to the rotating speed of the preset centrifugal motor under the condition of a preset first variance value;

the second-class rotating speed secondary adjusting mode is that the central control module uses a preset fourth rotating speed adjusting coefficient to secondarily adjust the rotating speed of the centrifugal motor to a third rotating speed under the condition of a preset second variance difference value;

The third type of rotation speed secondary adjustment mode is that the central control module uses a preset third rotation speed adjustment coefficient to secondarily adjust the rotation speed of the centrifugal motor to a fourth rotation speed under the condition of a preset third differential value;

the preset first variance condition is that the difference between the weight variation variance of the test tube and the preset first variance is smaller than or equal to the preset first variance; the preset second variance difference condition is that the difference between the weight variation variance of the test tube and the preset first variance is larger than the preset first variance difference and smaller than or equal to the preset second variance difference; the preset third variance difference condition is that the difference between the variance of the weight variation of the test tube and the preset first variance is larger than the preset second variance difference;

the preset first variance difference value is smaller than the preset second variance difference value, and the preset third rotating speed adjusting coefficient is smaller than the preset fourth rotating speed adjusting coefficient.

Further, the central control module controls the weight sensor to carry out secondary detection on the weight of the test tube in the extracting chamber when the secondary adjustment of the rotating speed of the centrifugal motor is completed, calculates the variance of the weight variation of the secondary detection test tube according to the secondary detection result, and determines two secondary judging modes of whether the water volatilization degree is in the allowable range according to the variance of the weight variation of the secondary detection test tube,

The second determination mode of the first type of volatilization degree is that the central control module secondarily determines that the moisture volatilization degree is within an allowable range under the condition of a preset fourth difference;

the second type of volatilization degree secondary judging mode is that the central control module secondarily judges that the moisture volatilization degree exceeds an allowable range under a preset fifth variance condition, and secondarily adjusts the inclination angle of the test tube to a second corresponding inclination angle by calculating the difference value between the weight variation variance of the secondarily detected test tube and the preset first variance;

the preset fourth difference condition is that the variance of the weight variation of the secondary detection test tube is smaller than or equal to a preset first variance; the preset fifth variance condition is that the variance of the weight variation of the secondary detection test tube is larger than the preset first variance.

Further, the central control module determines three secondary adjustment modes aiming at the inclination angle of the test tube according to the difference value between the variance of the weight variation of the secondary detection test tube and the preset first variance under the condition of the preset fifth variance, wherein,

the first type of secondary adjustment mode of the inclination angle is that the central control module secondarily adjusts the inclination angle of the test tube to a preset inclination angle under the condition of a preset fourth difference value;

The second type of inclination angle secondary adjustment mode is that the central control module uses a preset third inclination angle adjustment coefficient to secondarily adjust the inclination angle of the test tube to a third inclination angle under the condition of a preset fifth variance difference value;

the third type of secondary adjustment mode of the inclination angle is that the central control module uses a preset fourth inclination angle adjustment coefficient to secondarily adjust the inclination angle of the test tube to a fourth inclination angle under the condition of presetting a sixth variance difference value;

wherein the preset third inclination angle adjustment coefficient is smaller than the preset fourth inclination angle adjustment coefficient.

Further, the preset fourth difference condition is that the difference between the variance of the weight variation of the secondary detection test tube and the preset first variance is smaller than or equal to the preset first difference;

the preset fifth variance difference condition is that the difference value between the weight variation variance of the secondary detection test tube and the preset first variance is larger than the preset first variance difference value and smaller than or equal to the preset second variance difference value;

the preset sixth variance difference condition is that the difference between the variance of the weight variation of the secondary detection test tube and the preset first variance is larger than the preset second variance difference.

Compared with the prior art, the system has the beneficial effects that through the arranged bovine blood conveying module, the separating module, the extracting module and the central control module, the inclination angle of the test tube is adjusted to the first corresponding inclination angle according to the average increment of the temperature of the test tube in a unit period, so that whether the separating stability meets the requirement or not is accurately judged when the bovine blood is separated, and the influence of the irregularity of the temperature change on the separating stability is reduced; the rotating speed of the centrifugal motor is increased to a first corresponding rotating speed according to the volume ratio of the serum obtained through separation, and the accuracy of serum separation is improved through the adjustment of the rotating speed of the centrifugal motor; the rotating speed of the centrifugal motor is secondarily reduced to a second corresponding rotating speed according to the variance of the weight variation of the test tube, and whether the moisture volatilization degree of bovine blood in the test tube is in an allowable range or not is accurately judged by detecting the weight of the test tube and according to the variance of the weight variation; through the weight variation variance according to the test tube when accomplishing centrifugal motor rotational speed's secondary regulation with test tube inclination to the second and correspond inclination, reduced because the test tube inclination is too little to centrifugal effect's influence, realized the improvement to serum collection accuracy and stability.

Furthermore, the system of the invention reduces the influence on the acquisition stability due to inaccurate judgment on the separation stability and further realizes the improvement on the serum acquisition accuracy and stability by setting the preset first temperature and the preset second temperature and determining whether the separation stability is in the allowable range according to the average increment of the test tube temperature in the unit period.

Further, the system of the invention determines three types of adjustment modes for the inclination angle of the test tube according to the preset first temperature difference value, the preset second temperature difference value, the preset first inclination angle adjustment coefficient and the preset second inclination angle adjustment coefficient of the test tube temperature average increment and the preset first temperature difference value, reduces the influence of the irregularity of temperature change on the separation stability by adjusting the inclination angle of the test tube, and further improves the serum collection accuracy and stability.

Furthermore, according to the system, through the preset first volume ratio and the preset second volume ratio, whether the bovine blood sedimentation degree is in the allowable range or not is determined according to the volume ratio of the serum separated from the test tube, the influence on separation accuracy caused by inaccurate determination of the bovine blood sedimentation degree is reduced, and the improvement on serum collection accuracy and stability is further realized.

Furthermore, the system of the invention improves the accuracy of serum separation and further improves the accuracy and stability of serum collection by determining three types of adjustment modes of the rotating speed of the centrifugal motor according to the difference between the volume ratio of serum separated from the test tube and the preset first volume ratio through the preset first volume ratio difference and the preset second volume ratio difference.

Furthermore, the system of the invention reduces the influence on the stability of the centrifugal process due to inaccurate judgment of the moisture volatilization degree and further improves the serum collection accuracy and stability by setting the preset first variance and the preset second variance and determining whether the moisture volatilization degree is in the allowable range according to the variance of the weight change quantity of the test tube.

Furthermore, the system of the invention reduces the influence of insufficient stability of the centrifugal module caused by water volatilization on the stability of the serum separation process by determining three secondary adjustment modes for the rotating speed of the centrifugal motor according to the preset first variance difference and the preset second variance difference of the weight variation variance of the test tube and the preset first variance, and further improves the serum collection accuracy and stability.

Furthermore, the system of the invention reduces the influence of the moisture volatilization on the stability and the separation accuracy of the separation process and further realizes the improvement of the serum collection accuracy and stability by setting the preset first variance and determining whether the moisture volatilization degree is in the allowable range according to the weight change variance of the secondary detection test tube.

Further, the system of the invention determines three secondary adjustment modes for the inclination angle of the test tube according to the preset first variance difference value, the preset second variance difference value, the preset third inclination angle adjustment coefficient and the preset fourth inclination angle adjustment coefficient of the secondary detection test tube, thereby reducing the influence on the centrifugal effect caused by the too small inclination angle of the test tube and further realizing the improvement on the serum collection accuracy and stability.

Drawings

FIG. 1 is a schematic diagram of a bovine serum collection system based on intelligent separation according to an embodiment of the invention;

FIG. 2 is a block diagram of the overall structure of a bovine serum collection system based on intelligent separation according to an embodiment of the invention;

FIG. 3 is a block diagram of a separation module of a bovine serum collection system based on intelligent separation according to an embodiment of the invention;

Fig. 4 is a block diagram of a connection structure in which a separation module of the intelligent separation-based bovine serum collection system according to the embodiment of the present invention is connected to an extraction module and a central control module, respectively.

Detailed Description

In order that the objects and advantages of the invention will become more apparent, the invention will be further described with reference to the following examples; it should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the invention.

The preferred embodiments of the present invention will be described below with reference to the accompanying drawings, and it should be understood by those skilled in the art that these embodiments are merely for explaining the technical principles of the present invention, and are not intended to limit the scope of the present invention.

It should be noted that, in the description of the present invention, terms such as "upper," "lower," "left," "right," "inner," "outer," and the like indicate directions or positional relationships based on the directions or positional relationships shown in the drawings, which are merely for convenience of description, and do not indicate or imply that the apparatus or elements must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present invention.

Furthermore, it should be noted that, in the description of the present invention, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention can be understood by those skilled in the art according to the specific circumstances.

Referring to fig. 1, fig. 2, fig. 3, and fig. 4, the structure diagram, the overall structure diagram, the separation module structure diagram, and the connection structure diagram of the separation module respectively connected with the extraction module and the central control module of the bovine serum collection system based on intelligent separation according to the embodiment of the invention are shown; the embodiment of the invention provides a bovine serum collection system based on intelligent separation, which comprises the following components:

the bovine blood conveying module 1 is used for conveying the collected bovine blood into a corresponding container;

the separation module is connected with the bovine blood conveying module 1 and comprises a centrifugal unit 10 used for separating bovine blood and a centrifugal motor 8 connected with the centrifugal unit 10 and used for providing centrifugal rotation power, wherein an angle adjusting component 9 used for adjusting the inclination angle of a test tube and a test tube 11 movably connected with the angle adjusting component 9 and used for placing bovine blood are arranged in the centrifugal unit 10;

the extraction module is connected with the separation module and used for extracting the bovine serum separated by the separation module, and comprises a grabbing mechanical arm 2 arranged above the centrifugal unit, an extraction chamber 5 arranged below the grabbing mechanical arm 2 and used for providing a serum extraction place, and an extraction component 13 partially arranged above the extraction chamber 5 and used for extracting the bovine serum, wherein a visual detector 3 used for detecting the volume of the centrifuged serum and a weight sensor 6 arranged below the visual detector 3 and used for detecting the weight of a test tube in the extraction chamber 5 are arranged on the side wall inside the extraction chamber 5;

The central control module is respectively connected with the bovine blood conveying module 1, the separation module and the extraction module and is used for adjusting the inclination angle of the test tube to a first corresponding inclination angle according to the average increment of the temperature of the test tube in a unit period, adjusting the rotation speed of the centrifugal motor to the first corresponding rotation speed according to the volume ratio of serum separated from the test tube in the extraction chamber 5, secondarily adjusting the rotation speed of the centrifugal motor to a second corresponding rotation speed according to the variance of the weight variation of the test tube, and secondarily adjusting the inclination angle of the test tube to the second corresponding inclination angle according to the variance of the weight variation of the secondarily detected test tube when the secondary adjustment of the rotation speed of the centrifugal motor is completed.

Specifically, it will be appreciated by those skilled in the art that the preferred embodiment of the angle adjustment assembly 9 is an angle adjustable bracket.

Specifically, the test tube inclination angle refers to an inclination angle of the test tube with respect to the vertical direction.

Specifically, the drawing module further comprises a drawing motor 14 connected with the drawing assembly 13 and used for providing drawing power, a serum container 4 arranged below the drawing motor 14 and connected with the drawing assembly 13 and used for storing centrifuged serum, and a restraint assembly 7 arranged inside the drawing chamber 5 and used for restraining the vertical position of the test tube, and as a preferred embodiment of the invention, the restraint assembly 7 can be an mechanical arm with adjustable extension length, and the drawing assembly can be a drawing pipeline.

According to the system, through the arranged bovine blood conveying module 1, the separation module, the extraction module and the central control module, the inclination angle of the test tube is adjusted to the first corresponding inclination angle according to the average increment of the temperature of the test tube in a unit period, so that whether the separation stability meets the requirement or not is accurately judged when the bovine blood is separated, and the influence of the irregularity of the temperature change on the separation stability is reduced; the rotating speed of the centrifugal motor is increased to a first corresponding rotating speed according to the volume ratio of the serum obtained through separation, and the accuracy of serum separation is improved through the adjustment of the rotating speed of the centrifugal motor; the rotating speed of the centrifugal motor is secondarily reduced to a second corresponding rotating speed according to the variance of the weight variation of the test tube, and whether the moisture volatilization degree of bovine blood in the test tube is in an allowable range or not is accurately judged by detecting the weight of the test tube and according to the variance of the weight variation; through the weight variation variance according to the test tube when accomplishing centrifugal motor rotational speed's secondary regulation with test tube inclination to the second and correspond inclination, reduced because the test tube inclination is too little to centrifugal effect's influence, realized the improvement to serum collection accuracy and stability.

With continued reference to fig. 1, the central control module controls the temperature sensor 12 on the sidewall of the test tube in the centrifugal unit to detect the temperature of the test tube at the beginning and end of a single cycle, calculates the average increase of the temperature of the test tube in a unit cycle according to the detection result of the temperature of the test tube, and determines whether the separation stability is within the allowable range according to the average increase of the temperature of the test tube in the unit cycle,

the third type of judgment mode is that the central control module preliminarily judges that the bovine blood sedimentation degree is lower than the allowable range under the preset third temperature condition, and calculates the volume ratio of serum separated from the test tube in the extraction chamber 5 to judge whether the bovine blood sedimentation degree is in the allowable range for the second time;

Specifically, the average increase in tube temperature in a unit cycle is denoted as E, the preset first temperature is denoted as E1, the preset second temperature is denoted as E2, the difference between the average increase in tube temperature and the preset first temperature is denoted as Δe, and Δe=e-E1 is set, where E1 < E2.

Specifically, the specific sources of the preset first temperature and the preset second temperature are obtained through nearly thousands of experiments, namely, the separation speed of the experiments is within the standard speed and no faults occur when the separation speed is lower than or equal to the preset first temperature, the separation speed of the experiments is slower than the standard speed when the separation speed is between the preset first temperature and the preset second temperature, but the separation amount of the bovine blood is not reduced, and the fault condition exists, and the separation amount of the serum in the bovine blood is reduced when the separation speed is higher than or equal to the preset second temperature.

With continued reference to fig. 1 and 2, the central control module determines three types of adjustment modes for the inclination angle of the test tube according to the difference between the average increment of the test tube temperature and the preset first temperature under the preset second temperature condition, wherein,

Specifically, the preset first temperature difference is denoted as Δe1, the preset second temperature difference is denoted as Δe2, the preset first inclination angle adjustment coefficient is denoted as α1, the preset second inclination angle adjustment coefficient is denoted as α2, the preset inclination angle is denoted as Q0, Δe1 < Δe2,0 < α1 < α2 < 1, the adjusted tube inclination angle is denoted as Q ', Q' =q0×αi is set, wherein αi is the preset i-th inclination angle adjustment coefficient, and i=1, 2 is set.

Specifically, the acquisition process of the preset first temperature difference value and the preset second temperature difference value is the same as the acquisition process of the preset first temperature and the preset second temperature, and the acquisition process of the preset first inclination angle adjustment coefficient and the preset second inclination angle adjustment coefficient is obtained through experiments as follows: in the experiment, the separation stability is lower than the allowable range when the separation stability is lower than or equal to the preset first temperature difference value, the experiment process is not failed, the failure occurs when the second temperature difference value is preset, and the separation stability is lower than the allowable range.

With continued reference to fig. 1, the central control module determines whether the bovine blood sedimentation degree is within the allowable range according to the volume ratio of the serum separated from the test tube detected and calculated by the visual detector 3 under the preset third temperature condition, wherein,

Specifically, the volume ratio of serum separated from the test tube is denoted as D, the preset first volume ratio is denoted as D1, the preset second volume ratio is denoted as D2, the difference between the volume ratio of serum separated from the test tube and the preset first volume ratio is denoted as Δd, and Δd=d-D1 is set, wherein D1 is smaller than D2;

With continued reference to fig. 1, the central control module determines three types of adjustment modes for the rotational speed of the centrifugal motor according to the difference between the volume ratio of the serum separated from the test tube and the preset first volume ratio under the condition of the preset second volume ratio, wherein,

Specifically, the preset centrifugal motor rotation speed is denoted as V0, the preset first volume duty ratio difference is denoted as Δd1, the preset second volume duty ratio difference is denoted as Δd2, the preset first rotation speed adjustment coefficient is denoted as β1, the preset second rotation speed adjustment coefficient is denoted as β2, wherein Δd1 < [ Δd2 ], 1 < β1 < β2, the adjusted centrifugal motor rotation speed is denoted as V ', V' =v0× (1+βj)/2 is set, wherein βj is the preset j-th rotation speed adjustment coefficient, and j=1, 2 is set.

With continued reference to fig. 1 and 2, the central control module controls the weight sensor 6 to perform weight detection on the separated test tubes in the extracting chamber 5 one by one to obtain the weight of the separated test tubes, calculates the weight variation of the individual test tubes according to the weight of the separated individual test tubes and the initial weight of the individual test tubes, calculates the variance of the weight variation of the test tubes according to the weight variation of the individual test tubes, and determines whether the moisture volatilization degree is within the allowable range according to the variance of the weight variation of the test tubes,

wherein the preset first variance is smaller than the preset second variance.

Specifically, the variance of the weight change amount of the test tube is denoted as S, the preset first variance is denoted as S1, the preset second variance is denoted as S2, where S1 < S2, the difference between the variance of the weight change amount of the test tube and the preset first variance is denoted as Δs, and Δs=s-S1 is set.

With continued reference to fig. 1 and 3, the central control module determines three secondary adjustment modes for the rotational speed of the centrifugal motor according to the difference between the variance of the weight variation of the test tube and the preset first variance under the preset second variance condition, wherein,

Specifically, the preset first variance difference is denoted as Δs1, the preset second variance difference is denoted as Δs2, the preset third rotation speed adjustment coefficient is denoted as β3, the preset fourth rotation speed adjustment coefficient is denoted as β4, Δs1 < [ Δs2 ], 0 < β3 < β4 < 1, the secondarily adjusted rotation speed of the centrifugal motor is denoted as V ", V" =v' × (1+βk)/2 is set, βk is the preset kth rotation speed adjustment coefficient, and j=3, 4 is set.

With continued reference to fig. 1 and 3, the central control module controls the weight sensor 6 to perform secondary detection on the weight of the test tube in the drawing chamber 5 when secondary adjustment on the rotational speed of the centrifugal motor is completed, calculates a variance of the weight variation of the secondary detection test tube according to the secondary detection result, and determines two secondary determination modes of whether the moisture volatilization degree is within an allowable range according to the variance of the weight variation of the secondary detection test tube, wherein,

Specifically, the variance of the weight change amount of the secondary detection tube is noted as Sa, the difference between the variance of the weight change amount of the secondary detection tube and the preset first variance is noted as Δsa, and Δsa=sa-S1 is set.

With continued reference to fig. 1, the central control module determines three secondary adjustment modes for the inclination angle of the test tube according to the difference between the variance of the weight variation of the secondary detection test tube and the preset first variance under the preset fifth variance condition, wherein,

With continued reference to fig. 1, the preset fourth difference condition is that a difference between the variance of the weight variation of the secondary detection tube and the preset first variance is less than or equal to the preset first difference;

Specifically, the third inclination angle adjustment coefficient is preset to be α3, the fourth inclination angle adjustment coefficient is preset to be α4, wherein 1 < α3 < α4, the adjusted test tube inclination angle is Q ", Q" =q' ×αg is set, wherein αg is the preset g-th inclination angle adjustment coefficient, and g=3, 4 is set.

Example 1

In this embodiment 1, the central control module determines three types of adjustment modes for the inclination angle of the test tube according to the difference between the average increment of the temperature of the test tube and the preset first temperature under the preset second temperature condition, the preset first temperature difference is denoted as Δe1, the preset second temperature difference is denoted as Δe2, the preset first inclination angle adjustment coefficient is denoted as α1, the preset second inclination angle adjustment coefficient is denoted as α2, the preset inclination angle is denoted as Q0, wherein Δe1=4 ℃, Δe2=6 ℃, α1=0.8, α2=0.92, q0=20 °,

in this embodiment 1, Δe=5 ℃, the central control module determines Δe1 < Δe2and adjusts the tube inclination angle to the first inclination angle Q 'using a preset second inclination angle adjustment coefficient α2, so as to calculate Q' =20×0.92=18.4 °.

The system in this embodiment 1 through the preset first temperature difference value that sets up, preset second temperature difference value, preset first inclination angle adjustment coefficient and preset second inclination angle adjustment coefficient, through the difference according to test tube temperature average increase and preset first temperature confirm three kinds of regulation modes to test tube inclination angle, reduced because the inaccurate influence to collection stability to test tube inclination angle's regulation, realized the improvement to serum collection accuracy and stability.

Example 2

In this embodiment 2, the central control module determines three types of adjustment modes for the inclination angle of the test tube according to the difference between the average increment of the temperature of the test tube and the preset first temperature under the preset second temperature condition, the preset first temperature difference is denoted as Δe1, the preset second temperature difference is denoted as Δe2, the preset first inclination angle adjustment coefficient is denoted as α1, the preset second inclination angle adjustment coefficient is denoted as α2, the preset inclination angle is denoted as Q0, wherein Δe1=4 ℃, Δe2=6 ℃, α1=0.8, α2=0.92, q0=20 °,

in this embodiment 2, Δe=7deg.C, the central control module determines Δe > - Δe2 and adjusts the tube tilt angle to the second tilt angle Q 'using the preset first tilt angle adjustment coefficient α1, and calculates Q' =20° ×0.8=16°.

The system according to this embodiment 2 adjusts the test tube inclination to the corresponding value according to the average increment of the test tube temperature and the difference value of the preset first temperature through the preset first temperature difference value, the preset second temperature difference value, the preset first inclination angle adjustment coefficient and the preset second inclination angle adjustment coefficient, reduces the influence of the irregularity of the temperature variation on the separation stability through the adjustment of the test tube inclination angle, and achieves the improvement of the serum collection accuracy and stability.

Thus far, the technical solution of the present invention has been described in connection with the preferred embodiments shown in the drawings, but it is easily understood by those skilled in the art that the scope of protection of the present invention is not limited to these specific embodiments. Equivalent modifications and substitutions for related technical features may be made by those skilled in the art without departing from the principles of the present invention, and such modifications and substitutions will be within the scope of the present invention.

Claims

1. Bovine serum collection system based on intelligence separation, characterized by comprising:

the bovine blood conveying module is used for conveying the collected bovine blood into the corresponding container;

The separation module is connected with the bovine blood conveying module and comprises a centrifugal unit for separating bovine blood and a centrifugal motor which is connected with the centrifugal unit and is used for providing centrifugal rotation power, wherein an angle adjusting component for adjusting the inclination angle of the test tube and the test tube which is movably connected with the angle adjusting component and is used for placing bovine blood are arranged in the centrifugal unit;

the extraction module is connected with the separation module and used for extracting the bovine serum separated by the separation module, and comprises a grabbing mechanical arm arranged above the centrifugal unit, an extraction chamber arranged below the grabbing mechanical arm and used for providing a serum extraction place, and an extraction assembly partially arranged above the extraction chamber and used for extracting the bovine serum, wherein a visual detector used for detecting the volume of the centrifuged serum and a weight sensor arranged below the visual detector and used for detecting the weight of a test tube in the extraction chamber are arranged on the side wall inside the extraction chamber;

the central control module is respectively connected with the bovine blood conveying module, the separation module and the extraction module and is used for adjusting the inclination angle of the test tube to a first corresponding inclination angle according to the average increment of the temperature of the test tube in a unit period, adjusting the rotating speed of the centrifugal motor to the first corresponding rotating speed according to the volume ratio of serum separated from the test tube in the extraction chamber, secondarily adjusting the rotating speed of the centrifugal motor to a second corresponding rotating speed according to the variance of the weight variation of the test tube, and secondarily adjusting the inclination angle of the test tube to the second corresponding inclination angle according to the variance of the weight variation of the secondarily detected test tube when the secondary adjustment of the rotating speed of the centrifugal motor is completed.

2. The intelligent separation-based bovine serum collection system according to claim 1, wherein the central control module controls a temperature sensor provided on a side wall of a test tube in the centrifugal unit to detect a test tube temperature at a start and end of a single cycle, calculates an average increase of the test tube temperature in a unit cycle according to a test tube temperature detection result, and determines three kinds of determination modes whether separation stability is within an allowable range according to the average increase of the test tube temperature in the unit cycle,

3. The intelligent separation-based bovine serum collection system of claim 2, wherein said central control module determines three types of adjustment modes for the inclination angle of the test tube according to the difference between the average increase of the temperature of the test tube and the preset first temperature under the preset second temperature condition, wherein,

4. The intelligent separation-based bovine serum collection system according to claim 3, wherein said central control module determines whether the bovine blood sedimentation degree is within the allowable range according to the volume ratio of the serum separated from the test tube detected and calculated by said visual detector under the preset third temperature condition, wherein,

5. The intelligent separation-based bovine serum collection system according to claim 4, wherein the central control module determines three types of adjustment modes for the rotational speed of the centrifugal motor according to the difference between the volume ratio of the serum separated from the test tube and the preset first volume ratio under the preset second volume ratio condition,

6. The intelligent separation-based bovine serum collection system according to claim 5, wherein the central control module controls the weight sensor to perform weight detection on the separated test tubes one by one in the drawing chamber to obtain the weight of the separated test tubes, calculates the weight variation of the individual test tubes according to the weight of the separated individual test tubes and the initial weight of the individual test tubes, calculates the variance of the weight variation of the test tubes according to the weight variation of the individual test tubes, and determines three types of determination modes whether the moisture volatilization degree is within an allowable range according to the variance of the weight variation of the test tubes,

wherein the preset first variance is smaller than the preset second variance.

7. The intelligent separation-based bovine serum collection system according to claim 6, wherein the central control module determines three secondary adjustment modes for the rotational speed of the centrifugal motor according to the difference between the variance of the weight variation of the test tube and the preset first variance under the preset second variance condition, wherein,

8. The intelligent separation-based bovine serum collection system according to claim 7, wherein the central control module controls the weight sensor to perform secondary detection on the weight of the test tube in the drawing chamber when the secondary adjustment of the rotation speed of the centrifugal motor is completed, calculates a variance of the weight variation of the secondary detection test tube according to the secondary detection result, and determines two secondary determination modes of whether the moisture volatilization degree is within an allowable range according to the variance of the weight variation of the secondary detection test tube, wherein,

9. The intelligent separation-based bovine serum collection system according to claim 8, wherein the central control module determines three types of secondary adjustment modes for the inclination angle of the test tube according to the difference between the variance of the weight variation of the secondary detection test tube and the preset first variance under the preset fifth variance condition,

10. The intelligent separation-based bovine serum collection system of claim 9, wherein said predetermined fourth difference condition is that the difference between the variance of the weight variation of the secondary test tube and the predetermined first variance is less than or equal to the predetermined first difference;