CN116267901A - Human body local tumor preservation device - Google Patents

Human body local tumor preservation device Download PDF

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Publication number
CN116267901A
CN116267901A CN202310565531.4A CN202310565531A CN116267901A CN 116267901 A CN116267901 A CN 116267901A CN 202310565531 A CN202310565531 A CN 202310565531A CN 116267901 A CN116267901 A CN 116267901A
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sliding
bin
storage bin
positioning rod
local tumor
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CN202310565531.4A
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CN116267901B (en
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郑爱民
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Shandong Provincial Hospital Affiliated to Shandong First Medical University
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Shandong Provincial Hospital Affiliated to Shandong First Medical University
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/04Devices for withdrawing samples in the solid state, e.g. by cutting
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0236Mechanical aspects
    • A01N1/0263Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02Internal fittings
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02Internal fittings
    • B65D25/10Devices to locate articles in containers
    • B65D25/102Straps, bands, strings or other elongate elements
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P70/00Climate change mitigation technologies in the production process for final industrial or consumer products
    • Y02P70/10Greenhouse gas [GHG] capture, material saving, heat recovery or other energy efficient measures, e.g. motor control, characterised by manufacturing processes, e.g. for rolling metal or metal working

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mechanical Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
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Abstract

The application discloses a human body local tumor preservation device, which relates to the technical field of human body local preservation equipment and comprises an outer shell, a clamping and positioning assembly and a cutting assembly; the main body of the outer shell is hollow cylindrical; the clamping and positioning assembly comprises two sliding clamping frames with the same structure and two binding rope groups; the sliding clamping frame is positioned on the shifting guide rail on the outer shell in a sliding way; the binding rope group is a plurality of parallel binding ropes, and one sliding clamping frame corresponds to one group of binding ropes; both ends of the binding rope are fixed on the sliding clamping frame; the binding rope consists of a section of non-elastic part and two sections of elastic parts, and the elastic parts are positioned at two ends of the non-elastic part; the main body of the cutting assembly is a cutting knife and is used for sliding the storage bin so as to cut part of tumor samples; the technical effects that the whole sample is not easy to pollute when the human body local tumor preservation device takes out a part of the tumor in preservation, the process is relatively simple and convenient, and the damage to the sample is small are realized.

Description

Human body local tumor preservation device
Technical Field
The invention relates to the technical field of local human body preservation equipment, in particular to a local human body tumor preservation device.
Background
Currently, hospitals and research institutions are generally required to sample the tumor of patients in order to detect and treat the tumor during the research and treatment of the tumor; taking out a tumor specimen in the body of a patient through clinical living body sampling, and detecting the tumor specimen to judge the tumor condition and the subsequent treatment; in the subsequent treatment process, the taken tumor specimen can be subjected to secondary detection according to the treatment condition of the patient.
The tumor samples sampled after the operation are transported and stored in a certain environment, however, most of the current tumor samples are transported to a clinical laboratory by using a transparent plastic clamp or a plastic bag and other flexible packages, and the clinical laboratory is tested and then placed into a specimen culture cup for specimen storage;
during transportation, storage and multiple times of taking out (single sample taking out twice or taking out a part of the sample each time), damage and pollution may be caused to the sample (all or part of the samples are taken out multiple times to easily pollute the sample), and when the sample is cut, a cutting platform needs to be built in advance, and the cutting platform and the cutting knife need to be cleaned after cutting.
Therefore, a specimen storage device capable of placing a specimen after operation, cutting a specimen in a closed state, facilitating the cutting process, and facilitating the taking out of the specimen inside is needed.
Disclosure of Invention
The embodiment of the application solves the technical problems that in the prior art, the human body local tumor preservation device easily pollutes the whole sample when taking out a part of the tumor in preservation, the taking out process is inconvenient and large damage is easily caused to the sample, and the technical effects that the human body local tumor preservation device does not easily pollute the whole sample when taking out a part of the tumor in preservation, the process is relatively simple and convenient and the damage to the sample is small are realized.
The embodiment of the application provides a human body local tumor preservation device, which comprises an outer shell, a clamping and positioning assembly and a cutting assembly;
the outer shell body is hollow cylindrical;
the clamping and positioning assembly comprises two sliding clamping frames with the same structure and two binding rope groups;
the sliding clamping frame is positioned on the shifting guide rail on the outer shell in a sliding way;
the binding rope group is a plurality of parallel binding ropes, and one sliding clamping frame corresponds to one group of binding ropes;
the binding ropes of the same group are fixed on the same sliding clamping frame, and the number of the binding ropes in one group is more than 20;
both ends of the binding rope are fixed on the sliding clamping frame;
the binding rope consists of a section of non-elastic part and two sections of elastic parts, and the elastic parts are positioned at two ends of the non-elastic part;
when in use, the non-elastic part of the binding rope is abutted against the tumor sample to be stored;
the main body of the cutting assembly is a cutting knife and is used for sliding the storage bin so as to cut part of tumor samples.
Further, the outer shell comprises a storage bin, a collection bin, a taking-out bin, an upper cover and an observation window;
the storage bin is integrally tubular, and a shift guide rail with the length direction identical to the axial direction of the storage bin is arranged on the side wall of the storage bin;
the collecting bin is in a horn shape with a large upper part and a small lower part, and the top of the collecting bin is fixed at the bottom edge of the storage bin;
the taking-out bin is of a box structure and is fixed at the bottom of the collecting bin;
a sealing valve is arranged between the taking-out bin and the collecting bin;
the top of the taking-out bin is provided with a taking-out port, the bottom of the taking-out bin is provided with a waste discharge port, and the taking-out port and the waste discharge port are provided with cover plates;
the upper cover is detachably positioned at the top of the storage bin;
the observation window is positioned on the storage bin and the taking-out bin and used for observing the states inside the storage bin and the taking-out bin.
Further, a sliding block is arranged on the sliding clamping frame, rubber wheels which are closely arranged on the shifting guide rail and a motor for driving the wheels to rotate are arranged in the sliding block, and the sliding block is positioned on the shifting guide rail in a sliding mode.
Further, the cutting assembly comprises a first positioning rod, a second positioning rod, a cutter bracket and a cutting cutter;
the first positioning rod and the second positioning rod are rod bodies;
the first positioning rod is transversely arranged and fixed on the side wall of the storage bin close to the bottom, and the axis of the first positioning rod is perpendicular to the axis of the storage bin;
the second positioning rod is positioned on the first positioning rod in a sliding way;
a sliding block is fixed on the second positioning rod and slides along the first positioning rod under the control of the control unit; the second positioning rod is always perpendicular to the first positioning rod.
Further, the cutter bracket is longitudinally arranged and is in a rod shape or a frame structure, and can stretch and retract along the axis of the cutter bracket under the control of the control unit;
the cutting tool is in a flat strip shape and is fixed at the top of the tool support, and the length direction of the cutting tool is the same as that of the tool support.
Preferably, the cutter support is an electric telescopic rod.
Preferably, the device further comprises an inner support body, wherein the inner support body is tubular;
the shifting guide rails are arranged on the inner support body, and the clamping and positioning assembly is positioned on the inner support body;
the cutting assembly is positioned on an inner wall of the storage bin;
the inner support body is rotationally connected to the inner wall of the storage bin through a support body rotating assembly, and the axial direction of the rotating shaft is perpendicular to the axial direction of the inner support body;
the sliding clamping frame is positioned on the shifting guide rail on the inner wall of the inner support body in a sliding manner and can rotate around the axis of the sliding clamping frame;
the sliding block comprises a first block body and a second block body, the first block body is positioned on the first positioning rod in a sliding way, the second block body is fixedly connected to the first block body in a rotatable way, the second block body rotates under the control of the control unit, and the axial direction of a rotating shaft of the second block body is the same as the axial direction of the storage bin;
the second block is fixed on the second positioning rod.
Further, the sliding clamping frame comprises an outer frame body and an inner frame body, and the outer frame body and the inner frame body are annular;
the inner frame body is rotatably connected to the outer frame body.
Preferably, the elastic part is an elastic rubber tube with built-in magnetic powder or magnetic fluid.
Preferably, the device also comprises a density adjusting component, wherein the density adjusting component comprises a pressure equalizing annular bag, a pumping component and a swelling limiting plate group;
the pressure equalizing annular bag is an annular tubular bag body and is tightly attached to the sliding clamping frame;
the elastic parts are elastic hollow tubes, and the elastic parts of a group of binding ropes are communicated with the same pressure equalizing annular bag;
the pumping assembly is a miniature air pump and is used for adjusting the gas quantity in the pressure equalizing annular bag;
the expansion limiting plate group comprises a first annular plate and a second annular plate, the first annular plate and the second annular plate are annular plate bodies and are fixed on the side wall of the inner frame body far away from the outer frame body, and a gap between the first annular plate and the second annular plate is 0.3-0.6 cm;
the elastic part is positioned between the first annular plate and the second annular plate and is tightly attached together in a normal state; when the pressure equalizing ring-shaped bag is used, the gas quantity in the pressure equalizing ring-shaped bag can be controlled according to the size of a sample, so that the elastic part is expanded and contracted, and the degree of the density of the binding rope is controlled.
One or more technical solutions provided in the embodiments of the present application at least have the following technical effects or advantages:
the device for preserving the local tumor of the human body in the prior art is optimized and improved, a tumor sample is fixed in a clamping mode, and the sample is cut by using a built-in cutting knife; the technical problems that in the prior art, the whole sample is easy to pollute when a part of the human body local tumor preservation device is taken out of a tumor in preservation, the taking out process is inconvenient and large damage is easy to be caused to the sample are effectively solved, and the technical effects that the whole sample is difficult to pollute when the human body local tumor preservation device is taken out of a part of the tumor in preservation, the process is relatively simple and convenient (a cutting platform is not required to be built in advance, the cutting platform and the cutting knife are not required to be cleaned after cutting) and the damage to the sample is small are further achieved.
Drawings
FIG. 1 is a schematic view showing the internal structure of a device for preserving human local tumor according to the present invention;
FIG. 2 is a schematic view showing the external appearance of the device for preserving local tumor of human body according to the present invention;
FIG. 3 is a schematic diagram showing the positional relationship between a sliding clamping frame and a cutting assembly of the device for preserving human local tumor of the present invention;
FIG. 4 is a schematic structural view of a cutting assembly of the device for preserving human local tumor of the present invention;
FIG. 5 is a schematic view of the tether line of the device for preserving localized tumor of human body according to the present invention;
FIG. 6 is a schematic view of the internal support of the device for preserving human local tumor of the present invention;
FIG. 7 is a schematic view of the elastic part of the device for preserving human local tumor of the present invention;
FIG. 8 is a schematic diagram of the density adjusting assembly of the human body local tumor preservation device of the present invention;
FIG. 9 is a schematic diagram showing the structure of the expansion limiting plate set of the apparatus for preserving a local tumor of a human body according to the present invention.
In the figure:
the device comprises an outer shell 100, a storage bin 110, a displacement guide rail 111, a collection bin 120, a taking-out bin 130, a sealing valve 131, a taking-out port 132, a waste outlet 133, an upper cover 140 and an observation window 150;
clamping and positioning assembly 200, sliding clamping frame 210, outer frame 211, inner frame 212, binding rope set 220, elastic part 221, non-elastic part 222;
a cutting assembly 300, a first positioning rod 310, a sliding block 311, a second positioning rod 320, a cutter holder 330, a cutting cutter 340;
an inner supporter 400, a supporter rotating assembly 410;
a density adjusting assembly 500, a pressure equalizing ring-shaped bladder 510, a pumping assembly 520, a expansion restricting plate group 530, a first annular plate 531, and a second annular plate 532.
Detailed Description
In order that the invention may be readily understood, a more complete description of the invention will be rendered by reference to the appended drawings; the preferred embodiments of the present invention are illustrated in the drawings, however, the present invention may be embodied in many different forms and is not limited to the embodiments described herein; rather, these embodiments are provided so that this disclosure will be thorough and complete.
It should be noted that the terms "vertical", "horizontal", "upper", "lower", "left", "right", and the like are used herein for illustrative purposes only and do not represent the only embodiment.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs; the terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention; the term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.
Please refer to fig. 1, which is a schematic diagram illustrating an internal structure of a device for preserving local tumor of human body according to the present invention; according to the method, the device for preserving the local tumor of the human body in the prior art is optimized and improved, a tumor sample is fixed in a clamping mode, and the sample is cut by using the built-in cutting knife; the device has the advantages that the device can not pollute the whole sample easily when a part of the tumor in the preservation is taken out, is relatively simple and convenient in process (does not need to construct a cutting platform in advance, and the like, and also does not need to clean the cutting platform and the cutting knife after cutting), and has small damage to the sample.
Example 1
As shown in fig. 1 to 3, the human body partial tumor preservation device of the present application includes an outer housing 100, a clamping and positioning assembly 200, a cutting assembly 300, a power assembly, and a control unit.
The outer housing 100 is used for carrying the clamping and positioning assembly 200 and the cutting assembly 300, and storing human tumors; the outer housing 100 includes a storage bin 110, a collection bin 120, a take-out bin 130, an upper cover 140, and a viewing window 150;
the storage bin 110 is integrally tubular, and a shift guide rail 111 having the same length direction as the axial direction of the storage bin 110 is arranged on the side wall of the storage bin 110, and the shift guide rail 111 is used for guiding the movement of the clamping and positioning assembly 200; the shift rail 111 is a straight rail;
the collecting bin 120 is in a horn shape with a big top and a small bottom, and the top is fixed at the bottom edge of the storing bin 110;
as shown in fig. 2, the extraction bin 130 is a box structure, and is fixed at the bottom of the collection bin 120, for storing the excised tumor samples; a sealing valve 131 is arranged between the taking-out bin 130 and the collecting bin 120; the top of the extraction bin 130 is provided with an extraction port 132, the bottom is provided with a waste discharge port 133, and the extraction port 132 and the waste discharge port 133 are respectively provided with a cover plate for respectively extracting the tumor sample in the collection bin 120 and discharging the preservation solution in the extraction bin 130;
the upper cover 140 is detachably positioned on the top of the storage bin 110, and is used for closing the storage bin 110;
the viewing window 150 is positioned on the storage bin 110 and the take-out bin 130 for viewing the state inside the storage bin 110 and the take-out bin 130.
The storage bin 110 stores a sample storage liquid.
The clamping and positioning assembly 200 is used for fixing the tumor sample placed in the storage bin 110 in a clamping manner, and comprises two sliding clamping frames 210 and two binding rope groups 220;
the two sliding clamping frames 210 have the same structure and are annular frames, are positioned in the storage bin 110 in a sliding manner, and slide on the shift guide rail 111 under the control of the control unit;
further, a sliding block is provided on the sliding clamping frame 210, in which a rubber wheel and a motor for driving the wheel to rotate are disposed in close contact with the displacement guide rail 111, and the sliding block is slidably positioned on the displacement guide rail 111;
as shown in fig. 5, the binding rope set 220 is a plurality of binding ropes arranged in parallel, and one sliding clamping frame 210 corresponds to one set of binding ropes; the binding ropes of the same group are all fixed on the same sliding clamping frame 210, and the number of the binding ropes in one group is more than 20; both ends of the binding rope are fixed on the sliding clamping frame 210; the binding rope comprises an elastic part 221 and a non-elastic part 222, wherein the elastic part 221 is an elastic rope, the non-elastic part 222 is a non-elastic rope such as a nylon rope, a steel wire rope and the like, one binding rope consists of one non-elastic part 222 and two elastic parts 221, and the elastic parts 221 are positioned at two ends of the non-elastic part 222; in actual use, the inelastic portion 222 of the tether line abuts against the tumor sample to be preserved.
The main body of the cutting assembly 300 is a cutter for sliding the storage bin 110 to cut a part of the tumor sample; further, as shown in fig. 4, the cutting assembly 300 includes a first positioning rod 310, a second positioning rod 320, a cutter holder 330, and a cutting cutter 340;
the first positioning rod 310 and the second positioning rod 320 are rod bodies; the first positioning rod 310 is transversely arranged and fixed on the side wall of the storage bin 110 near the bottom, and the axis of the first positioning rod 310 is perpendicular to the axis of the storage bin 110; the second positioning rod 320 is slidably positioned on the first positioning rod 310;
a sliding block 311 is fixed on the second positioning rod 320, and the sliding block 311 slides along the first positioning rod 310 under the control of the control unit; the second positioning rod 320 is always perpendicular to the first positioning rod 310;
the cutter holder 330 is longitudinally arranged and is in a rod shape or a frame structure, and can stretch and retract along the axis thereof under the control of the control unit;
the cutting tool 340 is flat and strip-shaped, and is fixed on the top of the tool holder 330, and the length direction of the cutting tool 340 is the same as the length direction of the tool holder 330.
Preferably, the knife holder 330 is an electric telescopic rod.
The power component is used for providing power for the operation of each part of the human body local tumor preservation device, the control unit plays a role in controlling the coordinated operation of each part of the human body local tumor preservation device, and the coordinated operation of each part of the human body local tumor preservation device is the prior art and is not repeated here.
Preferably, the control unit is a combination of a programmable logic controller and a control key.
In the practical use process of the human body local tumor preservation device, the embodiment of the application comprises the following steps:
1. the user opens the upper cover 140, pulls out part of the binding rope set 220 on the upper sliding clamping frame 210, places the sample to be stored between the two sliding clamping frames 210, and covers the upper cover 140 (the whole sample taking out step is similar to the sample placing step);
2. controlling the two sliding clamping frames 210 to be close to each other so as to clamp the sample;
3. when only a part of the sample needs to be taken out, the cutter 340 is controlled to be moved to be inserted between the binding rope sets 220 and moved to cut the sample;
4. controlling the cutting tool 340 to move downwards so that the top of the cutting tool 340 is positioned between the two binding rope groups 220;
5. the cutting tool 340 is controlled to move to stir the binding rope, so that part of the sample to be taken off is out of the binding and falls down;
6. opening the closing valve 131 so that a part of the falling sample falls into the take-out bin 130; the closing valve 131 is closed and the sampling port 132 is opened to take out the sample.
The technical scheme in the embodiment of the application at least has the following technical effects or advantages:
the technical problems that in the prior art, the whole sample is easy to pollute when the part of the human body local tumor preservation device on the tumor in the preservation is taken out, the taking-out process is inconvenient and large damage is easily caused to the sample are solved, and the technical effects that the whole sample is difficult to pollute when the part of the human body local tumor preservation device on the tumor in the preservation is taken out, the process is relatively simple and convenient, and the damage to the sample is small are realized.
Example two
Considering that when the human body local tumor preservation device in the above-described embodiment actually cuts a sample, sometimes a desired sample portion is difficult to be completely cut and it is difficult to select a cutting point and a cutting direction completely according to the intention of an operator when cutting; therefore, the embodiment of the present application optimizes and improves the structure of the outer casing 100 based on the above embodiment, and adds the inner support 400, specifically:
as shown in fig. 6, the inner support 400 is tubular, the displacement guide rails 111 are all disposed on the inner support 400, and the clamping and positioning assembly 200 is positioned on the inner support 400; the cutting assembly 300 is positioned on the inner wall of the storage bin 110; the inner support 400 is rotatably connected to the inner wall of the storage bin 110 through a support rotating assembly 410, and the axial direction of the rotating shaft is perpendicular to the axial direction of the inner support 400; the support rotating assembly 410 is a combination of a rod and a motor, and the inner support 400 is driven by the support rotating assembly 410 to rotate, so that the spatial positions of the two sliding clamping frames 210 are changed during rotation;
the sliding clamping frame 210 is slidably positioned on the displacement guide rail 111 on the inner wall of the inner support 400; the sliding clamping frame 210 comprises an outer frame 211 and an inner frame 212, both of which are annular, wherein the outer frame 211 is slidably positioned on the inner wall of the inner support 400 and moves along the axial direction of the inner support 400; the inner frame 212 is rotatably connected to the outer frame 211, the inner frame 212 is internally provided with a motor and a gear, and the outer frame 211 is provided with a gear ring; the inner frame 212 rotates about its own axis (the axis of the slide clamp frame 210 coincides with the axis of its own rotation shaft) under the control of the control unit;
the sliding block 311 includes a first block and a second block; the first block is slidably positioned on the first positioning rod 310, the second block is rotatably and fixedly connected to the first block, and is rotated under the control of the control unit, and the axial direction of the rotating shaft of the second block is the same as the axial direction of the storage bin 110; the second block is fixed to the second positioning rod 320.
In the actual use process, the sliding clamping frame 210 can be controlled to lift and rotate and be matched with the inner support 400 to rotate to change the relative position between the binding rope set 220 and the sample, and then the cutting tool 340 can be controlled to shift and penetrate into the gap between the binding ropes so as to cut off the required part of the sample.
Preferably, as shown in fig. 7, the elastic portion 221 is an elastic rubber tube with magnetic powder or magnetic fluid inside, and can attract each other to reduce the possibility of the sample falling down when the sliding clamping frame 210 moves.
Example III
In order to further reduce the problem that samples fall out from the binding ropes when the sliding clamping frame 210 moves and the inner support 400 rotates, and enable the human body local tumor preservation device to be applicable to samples with different sizes, ensure the cutting view and ensure the stability of the samples, according to the embodiment of the application, a density adjusting assembly 500 is additionally arranged on the basis of the embodiment, and the gap between the binding ropes is adjusted through the density adjusting assembly 500 so as to adjust the interval between the binding ropes according to requirements; the method comprises the following steps:
as shown in fig. 8 and 9, the density adjusting assembly 500 includes a pressure equalizing ring-shaped bladder 510, a pumping assembly 520, and a expansion restricting plate group 530; the pressure equalizing annular bag 510 is an annular tubular bag body and is arranged close to the sliding clamping frame 210; the elastic parts 221 are elastic hollow tubes, and the elastic parts 221 of a group of binding ropes are communicated with the same pressure equalizing annular bag 510; the pumping assembly 520 is a micro air pump for adjusting the amount of air in the pressure equalizing annular bag 510; the expansion limiting plate group 530 includes a first annular plate 531 and a second annular plate 532, both of which are annular plate bodies, fixed to a side wall of the inner frame body 212 remote from the outer frame body 211, and a gap between the first annular plate 531 and the second annular plate 532 is 0.3 to 0.6 cm;
the elastic part 221 is located between the first annular plate 531 and the second annular plate 532, and is tightly attached together in a normal state, and in actual use, the amount of gas in the pressure equalizing annular bag 510 can be controlled according to the sample size, so that the elastic part 221 is expanded and contracted (the elastic parts 221 are mutually extruded after expanding), and the degree of tightness of the binding rope is controlled.
The above description is only of the preferred embodiments of the present invention and is not intended to limit the present invention, but various modifications and variations can be made to the present invention by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (10)

1. A human body local tumor preservation device, comprising an outer shell (100), characterized in that: also comprises a clamping and positioning assembly (200) and a cutting assembly (300);
the main body of the outer shell (100) is hollow cylindrical;
the clamping and positioning assembly (200) comprises two sliding clamping frames (210) with the same structure and two binding rope groups (220);
the sliding clamping frame (210) is positioned on a displacement guide rail (111) on the outer shell (100) in a sliding manner;
the binding rope group (220) is a plurality of parallel binding ropes, and one sliding clamping frame (210) corresponds to one group of binding ropes;
the binding ropes of the same group are all fixed on the same sliding clamping frame (210), and the number of the binding ropes in one group is more than 20;
both ends of the binding rope are fixed on the sliding clamping frame (210);
the binding rope consists of a section of non-elastic part (222) and two sections of elastic parts (221), and the elastic parts (221) are positioned at two ends of the non-elastic part (222);
when in use, the non-elastic part (222) of the binding rope is abutted against the tumor sample to be stored;
the body of the cutting assembly (300) is a cutting knife for sliding in the storage bin (110) to cut off a portion of the tumor sample.
2. The human local tumor preservation apparatus according to claim 1, wherein: the outer shell (100) comprises a storage bin (110), a collection bin (120), a taking-out bin (130), an upper cover (140) and an observation window (150);
the storage bin (110) is integrally tubular, and a shift guide rail (111) with the length direction identical to the axial direction of the storage bin (110) is arranged on the side wall of the storage bin;
the collecting bin (120) is in a horn shape with a big top and a small bottom, and the top of the collecting bin is fixed at the bottom edge of the storage bin (110);
the taking-out bin (130) is of a box structure and is fixed at the bottom of the collecting bin (120);
a sealing valve (131) is arranged between the taking-out bin (130) and the collecting bin (120);
the top of the taking-out bin (130) is provided with a taking-out port (132), the bottom of the taking-out bin is provided with a waste discharge port (133), and the taking-out port (132) and the waste discharge port (133) are provided with cover plates;
the upper cover (140) is detachably positioned on the top of the storage bin (110);
the observation window (150) is positioned on the storage bin (110) and the taking-out bin (130) and is used for observing the states inside the storage bin (110) and the taking-out bin (130).
3. The human local tumor preservation apparatus according to claim 2, wherein: the sliding clamping frame (210) is provided with a sliding block, a rubber wheel which is arranged in close contact with the shifting guide rail (111) and a motor for driving the wheel to rotate are arranged in the sliding block, and the sliding block is positioned on the shifting guide rail (111) in a sliding mode.
4. The human local tumor preservation apparatus according to claim 2, wherein: the cutting assembly (300) includes a first positioning rod (310), a second positioning rod (320), a cutter support (330), and a cutting cutter (340);
the first positioning rod (310) and the second positioning rod (320) are rod bodies;
the first positioning rod (310) is transversely arranged and fixed on the side wall of the storage bin (110) close to the bottom, and the axis of the first positioning rod (310) is perpendicular to the axis of the storage bin (110);
the second positioning rod (320) is slidably positioned on the first positioning rod (310);
a sliding block (311) is fixed on the second positioning rod (320), and the sliding block (311) slides along the first positioning rod (310) under the control of the control unit; the second positioning rod (320) is always perpendicular to the first positioning rod (310).
5. The human local tumor preservation apparatus according to claim 4, wherein: the cutter bracket (330) is longitudinally arranged and is of a rod-shaped or frame structure, and can stretch and retract along the axis of the cutter bracket under the control of the control unit;
the cutting tool (340) is in a flat strip shape and is fixed at the top of the tool support (330), and the length direction of the cutting tool (340) is the same as the length direction of the tool support (330).
6. The human local tumor preservation apparatus according to claim 5, wherein: the cutter bracket (330) is an electric telescopic rod.
7. The human local tumor preservation apparatus according to claim 4, wherein: the device also comprises an inner support body (400), wherein the inner support body (400) is tubular;
the displacement guide rails (111) are all arranged on the inner support body (400), and the clamping and positioning assembly (200) is positioned on the inner support body (400);
-the cutting assembly (300) is positioned on an inner wall of the storage bin (110);
the inner support body (400) is rotatably connected to the inner wall of the storage bin (110) through a support body rotating assembly (410), and the axial direction of the rotating shaft is perpendicular to the axial direction of the inner support body (400);
the sliding clamping frame (210) is positioned on a displacement guide rail (111) on the inner wall of the inner support body (400) in a sliding manner and can rotate around the axis of the sliding clamping frame;
the sliding block (311) comprises a first block body and a second block body, the first block body is positioned on the first positioning rod (310) in a sliding way, the second block body is fixedly connected to the first block body in a rotating way, the second block body rotates under the control of the control unit, and the axial direction of a rotating shaft of the second block body is the same as the axial direction of the storage bin (110);
the second block is fixed on a second positioning rod (320).
8. The human local tumor preservation apparatus according to claim 7, wherein: the sliding clamping frame (210) comprises an outer frame body (211) and an inner frame body (212), and the outer frame body and the inner frame body are annular;
the inner frame (212) is rotatably connected to the outer frame (211).
9. The human local tumor preservation apparatus according to claim 1, wherein: the elastic part (221) is an elastic rubber tube with built-in magnetic powder or magnetic fluid.
10. The human local tumor preservation apparatus according to claim 7, wherein: the device also comprises a density adjusting component (500), wherein the density adjusting component (500) comprises a pressure equalizing annular bag (510), a pumping component (520) and a expansion limiting plate group (530);
the pressure equalizing annular bag (510) is an annular tubular bag body and is tightly attached to the sliding clamping frame (210);
the elastic parts (221) are elastic hollow tubes, and the elastic parts (221) of a group of binding ropes are communicated with the same pressure equalizing annular bag (510);
the pumping assembly (520) is a miniature air pump and is used for adjusting the amount of air in the pressure equalizing annular bag (510);
the expansion limiting plate group (530) comprises a first annular plate (531) and a second annular plate (532), which are annular plate bodies, and are fixed on the side wall of the inner frame body (212) far away from the outer frame body (211), wherein the gap between the first annular plate (531) and the second annular plate (532) is 0.3-0.6 cm;
the elastic part (221) is positioned between the first annular plate (531) and the second annular plate (532) and is tightly attached together in a normal state; when in use, the air quantity in the pressure equalizing annular bag (510) can be controlled according to the sample size, so that the elastic part (221) is expanded and contracted to control the density degree of the binding rope.
CN202310565531.4A 2023-05-19 2023-05-19 Human body local tumor preservation device Active CN116267901B (en)

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