CN116262067A - Ablation target infusion method and device of infusion pump, infusion pump and storage medium - Google Patents

Ablation target infusion method and device of infusion pump, infusion pump and storage medium Download PDF

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CN116262067A
CN116262067A CN202111526338.7A CN202111526338A CN116262067A CN 116262067 A CN116262067 A CN 116262067A CN 202111526338 A CN202111526338 A CN 202111526338A CN 116262067 A CN116262067 A CN 116262067A
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perfusion
preset
ablation target
period
flow rate
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崔长杰
徐宏
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Hangzhou Kunbo Biotechnology Co Ltd
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Hangzhou Kunbo Biotechnology Co Ltd
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Priority to PCT/CN2022/137400 priority patent/WO2023109623A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00Medical syringes, e.g. enemata; Irrigators
    • A61M3/02Enemata; Irrigators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00Medical syringes, e.g. enemata; Irrigators
    • A61M3/02Enemata; Irrigators
    • A61M3/0233Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs
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    • A61M3/0258Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs the liquid being pumped by means of electric pumps
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    • A61B2018/00005Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00011Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
    • A61B2018/00029Cooling or heating of the probe or tissue immediately surrounding the probe with fluids open
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577Ablation
    • AHUMAN NECESSITIES
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    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00642Sensing and controlling the application of energy with feedback, i.e. closed loop control
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    • A61B2218/00Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2218/001Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body having means for irrigation and/or aspiration of substances to and/or from the surgical site
    • A61B2218/002Irrigation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3334Measuring or controlling the flow rate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3368Temperature

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Abstract

The invention relates to an ablation target perfusion method and device of an perfusion pump, the perfusion pump and a storage medium, wherein the method comprises the following steps: receiving a request for pouring the melting target, and pouring the melting target in a preset pouring mode in a current pouring period according to the request; a step of priming an ablation target, comprising: and in the current perfusion period, respectively carrying out perfusion on the ablation target for a first preset time length by using a preset first flow rate and carrying out perfusion on the ablation target for a second preset time length by using a preset second flow rate. The method, the device and the computer readable storage medium for infusing the ablation target start to infuse at the first flow rate and then infuse at the second flow rate in one infusion period, and the method, the device and the computer readable storage medium alternate in such a way that the temperature of the ablation target is in a proper range and cannot rise sharply, so that the control process of the infusion temperature of the infusion pump is simplified, and meanwhile, the better control of the temperature of the ablation target is realized.

Description

Ablation target infusion method and device of infusion pump, infusion pump and storage medium
Technical Field
The embodiment of the application relates to the technical field of medical equipment, in particular to an ablation target perfusion method and device of an perfusion pump, the perfusion pump and a storage medium.
Background
In the clinical surgery, the operation site (ablation target) has the conditions of high temperature and the generation of pollutants such as resected tissue, blood seepage, liquid seepage and the like, and a medical infusion pump is required to perform real-time cleaning and cooling on specific liquid infused into the operation site in the operation process, and has high requirements on the temperature and the flow rate of the infusion liquid.
The flow rate of the perfusion pump is regulated according to the temperature of the ablation target, the flow rate is high, the more heat is taken away, the faster the temperature is reduced, the less the flow rate is, the slower the temperature is reduced, when the temperature of the ablation target is overhigh, the flow rate of the perfusion pump needs to be increased, and when the temperature of the ablation target is reduced, the flow rate of the perfusion pump needs to be reduced. It is common practice to directly adjust the perfusion pump flow rate according to temperature, with too high a temperature increasing the flow rate and too low a temperature decreasing the flow rate. The method often causes untimely temperature reduction, causes the temperature of the ablation target to suddenly and rapidly rise, and even if the flow rate is maximized at the moment, the temperature of the ablation position cannot be immediately reduced, so that discomfort is brought to a patient, and even risks are brought to the operation of the patient.
Disclosure of Invention
The embodiment of the application provides an ablation target perfusion method and device of a perfusion pump, the perfusion pump and a storage medium, and can realize accurate control of the perfusion temperature of the perfusion pump.
In one aspect, an embodiment of the present application provides an ablation target perfusion method of an perfusion pump, including the steps of:
receiving a request for pouring an ablation target, and pouring the ablation target in a preset pouring mode in a current pouring period according to the request;
the step of infusing the ablation target in the current infusion period by using a preset infusion mode according to the request comprises the following steps:
in the current perfusion period, respectively carrying out perfusion for a first preset time length on the ablation target by using a preset first flow rate and carrying out perfusion for a second preset time length on the ablation target by using a preset second flow rate;
wherein the sum of the first preset duration and the second preset duration is equal to the duration of the current perfusion period.
An aspect of embodiments of the present application further provides an ablation target infusion device of an infusion pump, the device comprising:
the perfusion unit is used for receiving a request for perfusing the ablation target, and perfusing the ablation target in a preset perfusion mode in a current perfusion period according to the request;
the perfusion unit includes:
the perfusion subunit is used for respectively perfusing the ablation target for a first preset duration by using a preset first flow rate and perfusing the ablation target for a second preset duration by using a preset second flow rate in the current perfusion period;
wherein the sum of the first preset duration and the second preset duration is equal to the duration of the current perfusion period.
An aspect of an embodiment of the present application also provides a perfusion pump, including: a memory and a processor; the memory stores executable program code; the processor, coupled to the memory, invokes the executable program code stored in the memory to perform the ablation target perfusion method as provided by the above embodiments.
An aspect of the embodiments also provides a computer readable storage medium having stored thereon a computer program which, when executed by a processor, performs an ablation target perfusion method as provided by the above embodiments.
According to the method and the device, when the ablation target is perfused in a preset perfusion mode in a current perfusion period according to a request for perfusing the ablation target, the first preset duration of perfusion is performed on the ablation target by using the preset first flow rate, and the second preset duration of perfusion is performed on the ablation target by using the preset second flow rate, wherein the sum of the first preset duration and the second preset duration is equal to the duration of the current perfusion period, so that the ablation target is perfused in one perfusion period at the first flow rate and the second flow rate respectively, and the above steps are alternated, so that the temperature of the ablation target is in a proper range, the rapid rise of the temperature of the perfusion pump is avoided, the control process of the perfusion temperature of the perfusion pump is simplified, and meanwhile, the better control of the temperature of the ablation target is realized.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, a brief description will be given below of the drawings that are needed in the embodiments or the prior art descriptions, it being obvious that the drawings in the following description are some embodiments of the present invention, and that other drawings can be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a flow chart illustrating an implementation of a method for targeted ablation infusion for an infusion pump according to one embodiment of the present disclosure;
fig. 2 is a flowchart of an implementation of pouring an ablation target by using a preset pouring mode in a current pouring period according to a request in an ablation target pouring method of a pouring pump according to an embodiment of the present invention;
FIG. 3 is a flow chart illustrating an implementation of a method for targeted ablation delivery for an infusion pump according to another embodiment of the present invention;
FIG. 4 is a schematic structural view of an ablation target infusion device of an infusion pump according to an embodiment of the present disclosure;
FIG. 5 is a schematic structural view of an ablation target infusion device of an infusion pump according to an embodiment of the present disclosure; and
fig. 6 is a schematic hardware structure of a perfusion pump according to an embodiment of the present application.
Detailed Description
For the purposes of making the objects, technical solutions and advantages of the embodiments of the present application more clear, the technical solutions of the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Fig. 1 is a flowchart of an implementation of an ablation target perfusion method of an perfusion pump according to an embodiment of the present application. As shown in fig. 1, the method specifically includes:
step S101, a request for pouring the ablation target is received.
The embodiment of the application can be applied to a perfusion pump, in particular to a medical perfusion pump, so as to perfuse an ablation target by using corresponding perfusate. The ablation target may be a human or animal tissue perfused by an perfusion pump, for example, a surgical site of a surgical patient. The request for pouring the ablation target can be directly input by a user operating the pouring pump, or can be generated by triggering when the ablation target is detected to exceed the preset temperature, so that the utilization efficiency of the pouring pump is improved.
Step S102, pouring the melting target in the current pouring period by using a preset pouring mode according to the request.
In the embodiment of the application, the melting target is perfused in each perfusion period by using a preset perfusion mode until the perfusion is ended when a perfusion ending request input by a user is received. When the melting target is perfused in the current perfusion period according to the perfusion request by using a preset perfusion mode, as shown in fig. 2, the method comprises the following steps:
step 201, performing perfusion on an ablation target for a first preset duration by using a preset first flow rate.
Step S202, performing perfusion on the ablation target for a second preset time period by using a preset second flow rate, wherein the sum of the first preset time period and the second preset time period is equal to the time period of the current perfusion period.
In the embodiment of the present application, the execution sequence of steps S201 and S202 is not limited, and step S201 may be executed first, and then step S202 may be executed; alternatively, step S202 may be performed first, and then step S201 may be performed.
In this embodiment of the present application, the first flow rate and the second flow rate are different, and the first flow rate may be greater than the second flow rate or may be less than the second flow rate. Preferably, when the first flow rate is greater than the second flow rate, the first flow rate is the maximum output flow rate of the perfusate in the perfusate pump, and the second flow rate is the minimum output flow rate of the perfusate in the perfusate pump; when the first flow rate is smaller than the second flow rate, the first flow rate is the minimum output flow rate of the perfusate in the perfusion pump, and the second flow rate is the maximum output flow rate of the perfusate in the perfusion pump. Because the flow rate is big, the heat of taking away is much, and the temperature drops faster, and the flow rate is little, and the heat of taking away is little, and the temperature drops slower, the embodiment of the application is in a perfusion period with first flow rate, with second flow rate alternate perfusion for the temperature of ablation target is in suitable scope, and the temperature can not rise sharply, has simplified the control process of perfusion pump perfusion temperature, has realized the better control of ablation target temperature.
In order to improve the accuracy of temperature control, before the ablation target is perfused, the time length of the current perfusion period, the first flow rate, the second flow rate, the first preset time length and the second preset time length can be set according to the ablation target so as to accurately perfuse the ablation target, the sum of the first preset time length and the second preset time length is equal to the time length of the current perfusion period, and the accuracy of the perfusion periodic performance and the ablation target temperature control can be ensured, so that the perfusion is adjusted in time when the temperature changes.
According to the method and the device, when the ablation target is perfused in a current perfusion period in a preset perfusion mode according to a request for perfusing the ablation target, the first preset duration is used for perfusing the ablation target, the second preset duration is used for perfusing the ablation target, and the sum of the first preset duration and the second preset duration is equal to the duration of the current perfusion period, so that the ablation target is perfused in one perfusion period at the first flow rate and at the second flow rate respectively, and the temperature of the ablation target is in a proper range in such a way alternately, the temperature cannot be increased sharply, the control process of the perfusion temperature of the perfusion pump is simplified, and meanwhile, the better control of the temperature of the ablation target is realized.
Fig. 3 is a flowchart illustrating an implementation of an ablation target infusion method of an infusion pump according to another embodiment of the present application. As shown in fig. 3, the method specifically includes:
step S301, performing perfusion on an ablation target for a first preset duration by using a preset first flow rate.
Step S302, perfusion is carried out on the ablation target for a second preset time period by using a preset second flow rate, wherein the sum of the first preset time period and the second preset time period is equal to the time period of the current perfusion period.
The embodiment of the application can be applied to a perfusion pump, in particular to a medical perfusion pump, so as to perfuse an ablation target with corresponding liquid. In the embodiment of the application, the melting target is perfused in each perfusion period by using a preset perfusion mode until the perfusion is ended when a perfusion ending request input by a user is received. Specifically, the ablation target is irrigated for a first preset duration by using a preset first flow rate, and the ablation target is irrigated for a second preset duration by using a preset second flow rate. The sum of the first preset duration and the second preset duration is equal to the duration of the current perfusion period.
In the embodiment of the application, in consideration of different temperatures of the ablation targets, before the ablation targets are perfused for a first preset time period by using the preset first flow rate, the duration of the current perfusion period, the first flow rate, the second flow rate, the first preset time period and the second preset time period can be set according to the ablation targets so as to accurately perfuse the ablation targets, the sum of the first preset time period and the second preset time period is equal to the duration of the current perfusion period, and the accuracy of the perfusion periodic performance and the ablation target temperature control can be ensured, so that the perfusion is adjusted in time when the temperature changes.
Step S303, acquiring the temperature of the ablation target.
In the embodiment of the application, the detection of the temperature of the ablation target is always performed in real time, so that the temperature change condition of the ablation target is timely obtained. For example, a preset temperature sensor may detect the temperature of the ablation target in real time, so that a device implementing the procedure (e.g., a processor in the infusion pump) may acquire the temperature of the ablation target from the temperature sensor.
In one embodiment, the proportion of the first preset duration (i.e. the duration of the perfusion with the first flow rate) and the second preset duration (i.e. the duration of the perfusion with the second flow rate) in the period time may be adjusted according to the temperature of the ablation target.
One specific method of adjusting the ratio (taking the first flow rate greater than the second flow rate as an example) is described below through steps S304-S306.
Step S304, judging whether the temperature of the ablation target is greater than the upper limit value of the preset temperature range, if yes, executing step S305, otherwise, executing step S306.
In one embodiment, after the temperature of the ablation target is obtained, it is determined whether the temperature is greater than the upper limit value of the preset temperature range, if yes, step S305 is performed, otherwise step S306 is performed. Wherein the preset temperature range is a temperature range of an ablation target under normal conditions.
Step S305, increasing a first preset duration, and entering a next pouring period to pour the melting target in a preset pouring manner.
In this embodiment of the present application, since the duration of each perfusion period is the same, the first preset duration is increased and the second preset duration is reduced in this step. That is, the present application increases the first preset time period, that is, increases the proportion of the first preset time period in the perfusion period, and decreases the proportion of the second preset time period in the perfusion period.
In one embodiment, when the obtained temperature of the ablation target is greater than the upper limit value of the preset temperature range, the current temperature of the ablation target is indicated to be too high, the first preset time period is increased, the next infusion period is entered, and the step S301 is skipped to continue to infuse the ablation target, so that after the next infusion period is entered, the duty cycle of the infusion time of the first flow rate in the next infusion period is increased, and the temperature of the ablation target is steadily reduced. The duty cycle is understood to mean the proportion of the perfusion time of the first flow rate that is present in the period duration.
In one embodiment, when the first preset time period is increased, an increase ratio of the first preset time period in the next perfusion period may be calculated by using a formula p1= (t 1-t 2)/t 2, where p1 represents the increase ratio, t1 represents the acquired temperature of the ablation target, t2 represents the upper limit value of the preset temperature range, and then the first preset time period is increased according to the increase ratio, for example, the increased first preset time period may be calculated by using a formula s=s1×1+p1, S represents the increased first preset time period, and S1 represents the first preset time period under the current perfusion period. If the increased first preset time length is greater than or equal to the duration of the current perfusion period, the increased first preset time length can be set to be the duration of the perfusion period, that is, the ablation target is perfused by using the first flow rate in the whole period of the next perfusion period.
Step S306, judging whether the temperature of the ablation target is smaller than the lower limit value of the preset temperature range, if yes, executing step S307, otherwise, jumping to step S301;
in the embodiment of the present application, when the temperature of the ablation target is less than the lower limit value of the preset temperature range, it indicates that the current temperature of the ablation target is too low, and step S307 is performed. If the temperature of the ablation target is not less than the lower limit value of the preset temperature range, that is, the temperature of the ablation target is within the preset temperature range, the step S301 is skipped, that is, the next perfusion cycle is directly entered, so that the perfusion speed and the corresponding perfusion time duty ratio which are the same as those of the previous cycle continue to perfuse the ablation target.
Step S307, the first preset time period is reduced, and the next pouring period is entered to pour the melting target in a preset pouring mode.
In this embodiment of the present application, since the duration of each perfusion period is the same, the step reduces or shortens the first preset duration and increases the second preset duration. That is, the present application decreases the first preset time period, that is, decreases the proportion of the first preset time period in the perfusion period, and increases the proportion of the second preset time period in the perfusion period.
In one embodiment, when the temperature of the ablation target is less than the lower limit value of the preset temperature range, the current temperature of the ablation target is indicated to be too low, the first preset time period is reduced or shortened, the next infusion period is entered, and the step S301 is skipped to continue to infuse the ablation target, so that after the next infusion period is entered, the duty cycle of the infusion time of the first flow rate in the next infusion period is reduced, and the temperature of the ablation target is smoothly raised. Specifically, when the first preset time period is reduced, a reduction ratio of the first preset time period in the next perfusion period may be calculated by using a formula p2= (t 3-t 4)/t 4, where p2 represents the reduction ratio, t3 represents the acquired temperature of the ablation target, t4 represents the lower limit value of the preset temperature range, and then the first preset time period is reduced according to the reduction ratio, for example, the reduced first preset time period may be calculated by using a formula S '=s1× (1+p2), S' represents the reduced first preset time period, and S1 represents the first preset time period under the current perfusion period. If the reduced first preset duration is less than or equal to zero, the reduced first preset duration may be set to zero at this time, i.e., the ablation target is perfused using the second flow rate throughout the next perfusion cycle.
In the embodiment of the application, in a period duration, a preset first flow rate is used for carrying out first preset duration of perfusion on an ablation target, and a preset second flow rate is used for carrying out second preset duration of perfusion on the ablation target, wherein the sum of the first preset duration and the second preset duration is equal to the duration of a current perfusion period, the temperature of the ablation target is obtained in real time in the perfusion period, when the obtained temperature of the ablation target is greater than the upper limit value of a preset temperature range, the first preset duration is increased, the duty ratio of the perfusion time of the first flow rate in the next perfusion period is increased, so that the temperature of the ablation target is steadily reduced after the next perfusion period is entered, and when the temperature of the ablation target is smaller than the lower limit value of the preset temperature range, the first preset duration is reduced, the duty ratio of the perfusion time of the first flow rate in the next perfusion period is reduced, and the temperature of the ablation target is steadily increased after the next perfusion period is entered.
In another embodiment of the present application, the first flow rate is less than the second flow rate, and the ablation target may be perfused at a minimum flow rate (first flow rate) during the current perfusion period, and then perfused at a maximum flow rate (second flow rate), that is, the ablation target is perfused at a first preset time period using the preset first flow rate, and then perfused at a second preset time period using the preset second flow rate, where the sum of the first preset time period and the second preset time period is equal to the time period of the current perfusion period. When the obtained temperature of the ablation target is greater than the upper limit value of the preset temperature range, the first preset duration is reduced (meaning that the second preset duration is increased), and the next perfusion period is entered to perfuse the ablation target in a preset perfusion mode, wherein the perfusion time of the maximum flow rate is increased and the perfusion time of the minimum flow rate is reduced in the next perfusion period, so that the stable reduction of the temperature of the ablation target is realized. When the temperature of the ablation target is smaller than the lower limit value of the preset temperature range, the first preset duration is increased, the next perfusion period is entered to perfuse the ablation target in a preset perfusion mode, the perfusion time of the maximum flow rate is reduced, and the perfusion time of the minimum flow rate is increased in the next perfusion period, so that the stable rising of the temperature of the ablation target is realized.
Fig. 4 is a schematic structural diagram of an ablation target perfusion device of an perfusion pump according to an embodiment of the present application. For convenience of explanation, only portions relevant to the embodiments of the present application are shown. The device may be provided in a perfusion pump. The apparatus includes a perfusion unit 400 for receiving a request for perfusing a fusion target, and perfusing the fusion target according to the request by using a preset perfusion mode in a current perfusion period.
The perfusion unit 400 includes a perfusion sub-unit 401 for performing perfusion on the ablation target for a first preset duration using a preset first flow rate and performing perfusion on the ablation target for a second preset duration using a preset second flow rate, respectively, in a current perfusion period. Wherein the sum of the first preset duration and the second preset duration is equal to the duration of the current perfusion period.
According to the method and the device, when the ablation target is perfused in a current perfusion period by using a preset perfusion mode according to a request for perfusing the ablation target, the ablation target is perfused for a first preset time period by using a preset first flow rate, and the ablation target is perfused for a second preset time period by using a preset second flow rate, wherein the sum of the first preset time period and the second preset time period is equal to the time period of the current perfusion period, so that the ablation target is perfused alternately at the first flow rate and the second flow rate in one perfusion period, the temperature of the ablation target is in a proper range and cannot be increased sharply, the control process of the perfusion temperature of the perfusion pump is simplified, and meanwhile, the better control of the temperature of the ablation target is realized.
Specific embodiments of each unit may refer to the descriptions corresponding to the foregoing method embodiments specifically, and are not repeated herein.
Fig. 5 is a schematic structural diagram of an ablation target perfusion device of an perfusion pump according to an embodiment of the present application. For convenience of explanation, only portions relevant to the embodiments of the present application are shown. The device may be provided in a perfusion pump. The device comprises:
the pouring unit 510 is configured to receive a request for pouring the melting target, and pour the melting target in a preset pouring manner in a current pouring period according to the request;
a temperature acquisition unit 520 for acquiring a temperature of the ablation target;
a duration increasing unit 530, configured to increase a first preset duration when the acquired temperature of the ablation target is greater than an upper limit value of a preset temperature range, and enter a next perfusion period, and perfuse the ablation target in the next perfusion period by using a preset perfusion mode; and
and a duration reducing unit 540, configured to reduce the first preset duration when the acquired temperature of the ablation target is less than the lower limit value of the preset temperature range, and enter a next perfusion period, and perfuse the ablation target in the next perfusion period by using a preset perfusion mode.
The perfusion unit 510 includes a perfusion subunit 511, configured to perfuse the ablation target for a first preset duration using a preset first flow rate and perfuse the ablation target for a second preset duration using a preset second flow rate, respectively, in a current perfusion period. Wherein the sum of the first preset duration and the second preset duration is equal to the duration of the current perfusion period.
Specifically, the duration increasing unit 530 is configured to calculate an increasing proportion of the first preset duration in the next perfusion period according to a formula p1= (t 1-t 2)/t 2, where p1 represents the increasing proportion, t1 represents the acquired temperature of the ablation target, and t2 represents an upper limit value of the preset temperature range.
Specifically, the duration reduction unit 540 is configured to calculate a reduction ratio of the first preset duration in the next perfusion period according to a formula p2= (t 3-t 4)/t 4, where p2 represents the reduction ratio, t3 represents the acquired temperature of the ablation target, and t4 represents a lower limit value of the preset temperature range.
According to the embodiment of the application, the ablation target is perfused for a first preset time period by using the preset first flow rate, and is perfused for a second preset time period by using the preset second flow rate, wherein the first flow rate is larger than the second flow rate, the sum of the first preset time period and the second preset time period is equal to the time period of the current perfusion period, the temperature of the ablation target is detected in real time in the perfusion period, when the temperature of the ablation target is detected to be larger than the upper limit value of the preset temperature range, the first preset time period is increased, the duty ratio of the perfusion time of the first flow rate in the next perfusion period is increased, so that the temperature of the ablation target is steadily reduced after the next perfusion period is entered, and when the temperature of the ablation target is smaller than the lower limit value of the preset temperature range, the first preset time period is reduced, the duty ratio of the perfusion time of the first flow rate in the next perfusion period is reduced, and the temperature of the ablation target is steadily increased after the next perfusion period is entered.
Specific embodiments of each unit may refer to the descriptions corresponding to the foregoing method embodiments specifically, and are not repeated herein.
Fig. 6 is a schematic hardware structure of a perfusion pump according to an embodiment of the present application.
As shown in fig. 6, the infusion pump 10 may include control circuitry that may include storage and processing circuitry 30. The storage and processing circuitry 30 may include memory, such as hard drive memory, non-volatile memory (e.g., flash memory or other electronically programmable limited delete memory used to form solid state drives, etc.), volatile memory (e.g., static or dynamic random access memory, etc.), and the like, as embodiments of the present application are not limited. Processing circuitry in the storage and processing circuitry 30 may be used to control the operation of the infusion pump 10. The processing circuitry may be implemented based on one or more microprocessors, microcontrollers, digital signal processors, baseband processors, power management units, audio codec chips, application specific integrated circuits, display driver integrated circuits, and the like.
The storage and processing circuitry 30 may be used to run software in the perfusion pump 10, such as internet browsing applications, voice over internet protocol (Voice over Internet Protocol, VOIP) telephone call applications, email applications, media playing applications, operating system functions, and the like. Such software may be used to perform some control operations, such as image acquisition based on a camera, ambient light measurement based on an ambient light sensor, proximity sensor measurement based on a proximity sensor, information display functions implemented based on status indicators such as status indicators of light emitting diodes, touch event detection based on a touch sensor, functions associated with displaying information on multiple (e.g., layered) displays, operations associated with performing wireless communication functions, operations associated with collecting and generating audio signals, control operations associated with collecting and processing button press event data, and other functions in the perfusion pump 10, among others, without limitation, embodiments of the present application.
Further, the memory stores executable program code and a processor coupled to the memory invokes the executable program code stored in the memory to perform the ablation target irrigation method as described in the embodiments of fig. 1 and 3 above.
Wherein the executable program code includes various elements in the ablation target irrigation device as described in the embodiments of fig. 4 and 5 above, such as: and (5) a pouring unit.
The infusion pump 10 may also include an input-output circuit 42. The input-output circuit 42 may be used to enable the infusion pump 10 to input and output data, i.e., to allow the infusion pump 10 to receive data from an external device and also to allow the infusion pump 10 to output data from the infusion pump 10 to an external device. The input-output circuit 42 may further include a sensor 32. The sensors 32 may include ambient light sensors, proximity sensors based on light and capacitance, touch sensors (e.g., based on light touch sensors and/or capacitive touch sensors, where the touch sensors may be part of a touch display screen or may be used independently as a touch sensor structure), acceleration sensors, and other sensors, among others.
The input-output circuitry 42 may also include one or more displays, such as the display 14. The display 14 may comprise one or a combination of several of a liquid crystal display, an organic light emitting diode display, an electronic ink display, a plasma display, and a display using other display technologies. The display 14 may include an array of touch sensors (i.e., the display 14 may be a touch screen display). The touch sensor may be a capacitive touch sensor formed of an array of transparent touch sensor electrodes, such as Indium Tin Oxide (ITO) electrodes, or may be a touch sensor formed using other touch technologies, such as acoustic wave touch, pressure sensitive touch, resistive touch, optical touch, etc., as embodiments of the present application are not limited.
The infusion pump 10 may also include an audio assembly 36. The audio assembly 36 may be used to provide audio input and output functions for the perfusion pump 10. The audio components 36 in the infusion pump 10 may include a speaker, microphone, buzzer, tone generator, and other components for generating and detecting sound.
The communication circuit 38 may be used to provide the ability for the infusion pump 10 to communicate with external devices. The communication circuitry 38 may include analog and digital input/output interface circuitry, and wireless communication circuitry based on radio frequency signals and/or optical signals. The wireless communication circuitry in the communication circuitry 38 may include radio frequency transceiver circuitry, power amplifier circuitry, low noise amplifiers, switches, filters, and antennas. For example, the wireless communication circuitry in the communication circuitry 38 may include circuitry for supporting near field communication (Near Field Communication, NFC) by transmitting and receiving near field coupled electromagnetic signals. For example, the communication circuit 38 may include a near field communication antenna and a near field communication transceiver. The communication circuitry 38 may also include a cellular telephone transceiver and antenna, a wireless local area network transceiver circuit and antenna, and the like.
The infusion pump 10 may further include a battery, power management circuitry, and other input-output units 40. The input output unit 40 may include buttons, levers, click wheels, scroll wheels, touch pads, keypads, keyboards, cameras, light emitting diodes, and other status indicators, etc.
A user may input commands through the input output circuit 42 to control the operation of the perfusion pump 10, and may use the output data of the input output circuit 42 to enable receipt of status information and other outputs from the perfusion pump 10.
Further, an embodiment of the present invention further provides a computer readable storage medium, which may be provided in the perfusion pump in the above embodiments, and may be a memory in the storage and processing circuit 30 in the above embodiment shown in fig. 6. The computer readable storage medium has stored thereon a computer program which, when executed by a processor, implements the ablation target perfusion method described in the embodiments of fig. 1 and 3 described above. Further, the computer-readable medium may be any medium capable of storing a program code, such as a usb (universal serial bus), a removable hard disk, a Read-Only Memory (ROM), a RAM, a magnetic disk, or an optical disk.
It should be noted that, for the sake of simplicity of description, the foregoing method embodiments are all expressed as a series of combinations of actions, but it should be understood by those skilled in the art that the present invention is not limited by the order of actions described, as some steps may be performed in other order or simultaneously in accordance with the present invention. Further, those skilled in the art will appreciate that the embodiments described in the specification are all preferred embodiments, and that the acts and modules referred to are not necessarily all required for the present invention.
In the foregoing embodiments, the descriptions of the embodiments are emphasized, and for parts of one embodiment that are not described in detail, reference may be made to the related descriptions of other embodiments.
The foregoing describes the method, apparatus and computer readable storage medium for targeted ablation delivery provided by the present invention, and is not intended to limit the invention to any particular extent, as long as the scope of the invention is modified in light of the teachings of the embodiments of the present invention.

Claims (12)

1. An ablation target infusion method of an infusion pump, the method comprising the steps of:
receiving a request for pouring an ablation target, and pouring the ablation target in a preset pouring mode in a current pouring period according to the request;
the step of infusing the ablation target in the current infusion period by using a preset infusion mode according to the request comprises the following steps:
in the current perfusion period, respectively carrying out perfusion for a first preset time length on the ablation target by using a preset first flow rate and carrying out perfusion for a second preset time length on the ablation target by using a preset second flow rate;
wherein the sum of the first preset duration and the second preset duration is equal to the duration of the current perfusion period.
2. The method of claim 1, wherein the first flow rate is greater than the second flow rate, further comprising, after the step of perfusing the ablation target with a preset perfusion pattern during a current perfusion period according to the request:
acquiring the temperature of the ablation target;
and when the acquired temperature of the ablation target is greater than the upper limit value of the preset temperature range, increasing the first preset duration, entering a next perfusion period, and perfusing the ablation target in the next perfusion period by using a preset perfusion mode.
3. The method of claim 2, wherein the increasing the first preset time period comprises:
calculating an increase ratio of the first preset duration in the next perfusion period using the formula p1= (t 1-t 2)/t 2; wherein p1 represents the increasing proportion, t1 represents the acquired temperature of the ablation target, and t2 represents the upper limit value of the preset temperature range;
and increasing the first preset time period according to the increasing proportion.
4. The method as recited in claim 2, further comprising:
and when the acquired temperature of the ablation target is smaller than the lower limit value of the preset temperature range, reducing the first preset duration, entering a next perfusion period, and perfusing the ablation target in the next perfusion period by using a preset perfusion mode.
5. The method of claim 4, wherein the reducing the first preset time period comprises:
calculating a decrease ratio of the first preset duration in the next perfusion period using the formula p2= (t 3-t 4)/t 4; wherein p2 represents the reduction ratio, t3 represents the acquired temperature of the ablation target, and t4 represents the lower limit value of the preset temperature range;
and reducing the first preset time period according to the reduction proportion.
6. An ablative target infusion device of an infusion pump, the device comprising:
the perfusion unit is used for receiving a request for perfusing the ablation target, and perfusing the ablation target in a preset perfusion mode in a current perfusion period according to the request;
the perfusion unit includes:
the perfusion subunit is used for respectively perfusing the ablation target for a first preset duration by using a preset first flow rate and perfusing the ablation target for a second preset duration by using a preset second flow rate in the current perfusion period;
wherein the sum of the first preset duration and the second preset duration is equal to the duration of the current perfusion period.
7. The apparatus of claim 6, wherein the first flow rate is greater than the second flow rate, further comprising:
a temperature acquisition unit for acquiring a temperature of the ablation target; and
and the duration increasing unit is used for increasing the first preset duration and entering a next perfusion period when the acquired temperature of the ablation target is greater than the upper limit value of the preset temperature range, and perfusing the ablation target in the next perfusion period by using a preset perfusion mode.
8. The apparatus of claim 7, wherein the duration increasing unit is specifically configured to:
calculating an increase ratio of the first preset duration in the next perfusion period by using a formula p1= (t 1-t 2)/t 2, wherein p1 represents the increase ratio, t1 represents the acquired temperature of the ablation target, and t2 represents an upper limit value of the preset temperature range;
and increasing the first preset time period according to the increasing proportion.
9. The apparatus as recited in claim 7, further comprising:
and the duration reduction unit is used for reducing the first preset duration and entering a next perfusion period when the acquired temperature of the ablation target is smaller than the lower limit value of the preset temperature range, and perfusing the ablation target in the next perfusion period by using a preset perfusion mode.
10. The apparatus of claim 9, wherein the duration reduction unit is specifically configured to:
calculating a reduction ratio of the first preset duration in the next perfusion period by using a formula p2= (t 3-t 4)/t 4, wherein p2 represents the reduction ratio, t3 represents the acquired temperature of the ablation target, and t4 represents a lower limit value of the preset temperature range;
and reducing the first preset time period according to the reduction proportion.
11. A perfusion pump, the perfusion pump comprising:
a memory and a processor;
the memory stores executable program code;
the processor coupled with the memory, invoking the executable program code stored in the memory, performing the ablation target perfusion method of any one of claims 1-5.
12. A computer readable storage medium, on which a computer program is stored, characterized in that the computer program, when executed by a processor, implements the ablation target perfusion method of any one of claims 1 to 5.
CN202111526338.7A 2021-12-14 2021-12-14 Ablation target infusion method and device of infusion pump, infusion pump and storage medium Pending CN116262067A (en)

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PCT/CN2022/137400 WO2023109623A1 (en) 2021-12-14 2022-12-08 Ablation target perfusion method and apparatus for perfusion pump, perfusion pump, and storage medium

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US6409722B1 (en) * 1998-07-07 2002-06-25 Medtronic, Inc. Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue
US9855094B2 (en) * 2010-12-28 2018-01-02 St. Jude Medical, Atrial Fibrillation Division, Inc. Multi-rate fluid flow and variable power delivery for ablation electrode assemblies used in catheter ablation procedures
US9788891B2 (en) * 2010-12-28 2017-10-17 St. Jude Medical, Atrial Fibrillation Division, Inc. Ablation electrode assemblies and methods for using same
CN107307901B (en) * 2017-06-22 2021-05-11 心诺普医疗技术(北京)有限公司 Cryoablation system
CN109405327B (en) * 2018-12-26 2024-02-13 上海导向医疗***有限公司 Precooling device for cryotherapy and cryotherapy system

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