CN116251156A - Traditional Chinese medicine enema and preparation method and equipment thereof - Google Patents

Traditional Chinese medicine enema and preparation method and equipment thereof Download PDF

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CN116251156A
CN116251156A CN202211710385.1A CN202211710385A CN116251156A CN 116251156 A CN116251156 A CN 116251156A CN 202211710385 A CN202211710385 A CN 202211710385A CN 116251156 A CN116251156 A CN 116251156A
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traditional chinese
chinese medicine
medicine enema
rhizoma
vinegar
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刘芳
唐诗宇
易飞扬
陈思敏
唐学贵
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Affiliated Hospital of North Sichuan Medical College
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Abstract

The invention discloses a traditional Chinese medicine enema and a preparation method and equipment thereof, wherein the traditional Chinese medicine enema comprises, by weight, 9g of costustoot, 6g of combined spicebush root, 6g of mirabilite, 5g of oldenlandia diffusa, 10g of polygonum cuspidatum, 10g of herba patriniae, 10g of magnolia officinalis, 5g of glabrous greenbrier rhizome, 5g of crinis carbonisatus, 10g of vinegar corydalis tuber and 10g of stir-fried son.

Description

Traditional Chinese medicine enema and preparation method and equipment thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine enema and a preparation method and equipment thereof.
Background
Most colorectal cancers begin with polyps, which are overgrowth of colorectal intimal tissue, but not all polyps are malignant, and over time (typically many years) the polyps become cancerous, the chance of which depends on the type of polyp, two main types being: adenomatous polyps (adenoma) sometimes become cancers, so the polyps are called precancerous lesions, proliferative polyps and inflammatory polyps, the polyps are common, but are not precancerous lesions, the balance of flora in intestinal tracts is required to be maintained in the prevention and treatment of colorectal polyps, and the AI-resistant effect is improved.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine enema and a preparation method thereof, which are reasonable in formula, more scientific in preparation process, fine in liquid, small in toxic and side effects and convenient to prepare, and the traditional Chinese medicine enema and the preparation method thereof aim at improving local lesions of colorectal polyps and precancerous lesions of colorectal adenoma, restoring intestinal mucosa absorption, regulating intestinal flora imbalance, relieving toxic and side effects, regulating intestinal epithelial cell proliferation and migration, accelerating intestinal mucosa healing, controlling inflammation and having a targeted treatment effect.
The technical scheme adopted for solving the technical problems is as follows: the traditional Chinese medicine enema is provided, wherein the enema comprises the following raw materials in parts by weight: 9g of costustoot, 6g of combined spicebush root, 6g of mirabilite, 5g of oldenlandia diffusa, 10g of giant knotweed, 10g of patrinia herb, 10g of magnolia officinalis, 5g of glabrous greenbrier rhizome, 5g of crinis carbonisatus, 10g of vinegar-processed rhizoma corydalis and 10g of fried seeds.
Further, 12g of costustoot, 2g of combined spicebush root, 8g of mirabilite, 7g of oldenlandia diffusa, 10g of giant knotweed, 15g of herba patriniae, 20g of magnolia officinalis, 15g of glabrous greenbrier rhizome, 6g of crinis carbonisatus, 20g of vinegar-processed rhizoma corydalis and 20g of stir-fried rhizoma .
Further, the traditional Chinese medicine enema is prepared from the following traditional Chinese medicines in parts by weight: 7g of costustoot, 5g of combined spicebush root, 3g of mirabilite, 8g of oldenlandia diffusa, 13g of giant knotweed, 9g of patrinia herb, 13g of magnolia officinalis, 15g of glabrous greenbrier rhizome, 5g of crinis carbonisatus, 8g of vinegar-processed rhizoma corydalis and 13g of stir-fried rhizoma . A preparation method of a traditional Chinese medicine enema comprises the following steps:
s1: heating herba Hedyotidis Diffusae and herba Patriniae with strong fire in a drying chamber, adhering the plants in the wall, continuously tumbling for 20 min until the surface is dark brown, cooling, and sieving to remove impurity and debris;
s2: cleaning radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, vinegar-processed rhizoma corydalis, and parched rhizoma Ligustici Chuanxiong , removing soil particles, and oven drying;
s3: taking radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, vinegar rhizoma corydalis and parched fructus Sichuan , grinding with a high-pressure grinder, discharging into a filter, and filtering with 300 mesh sieve;
s4: mixing radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, rhizoma corydalis with vinegar, parched fructus Sichuan , herba Hedyotidis Diffusae, and herba Patriniae with wheel mill mixer, mixing, discharging into a steaming furnace, boiling with clear water, steaming for 30 min, and standing;
s5: filtering the cooled medicament with a 400-mesh screen to prepare a medicament, and filtering to obtain a traditional Chinese medicine enema;
s6: the prepared traditional Chinese medicine enema is packaged, and each 100ml of the traditional Chinese medicine enema is one dose.
Further, in step S1, the mass ratio of the oldenlandia diffusa to the patrinia is: herba Hedyotidis Diffusae: herba patriniae=5 to 3. Further, in step S3, the particle diameter is: 8mm.
Further, in step S4, the mass ratio of the medicinal materials to the clear water is: medicinal materials: clear water=1 to 1.5.
The preparation method promotes secretion of glutathione enzyme, detoxifies liver and eliminates enzyme.
The oldenlandia diffusa contains dad alcohol and ursolic acid, which are stigma alcohol, and the stigma alcohol reacts with intestinal cells to dilate blood vessels of intestinal walls.
The Toosendan inhibits fungi, candida albicans, cryptococcus neoformans, microsporum ferrugineum, staphylococcus aureus and relaxes sphincters.
The residual carbon nanofiber membrane can enable the content of bacteria [ (7.62+/-1.87) ×104 tissues/g ] in wound tissues to be lower than 105/g for an infected wound surface.
The inhibition of influenza virus and orphan virus and herpes simplex virus activity in humans.
The utility model provides a traditional chinese medicine enema's preparation facilities, includes grinding mechanism, drying mechanism, 300 mesh filter equipment, 400 mesh filter equipment, wheel grinds the mixer, the cooking machine, the apotheca, grinding mechanism includes spiral grinding page, the change machine, the outside left side of grinding mechanism is provided with first feed inlet, the inside top of grinding mechanism is provided with the second feed inlet, evenly set up 300 mesh filter equipment in the middle of the grinding mechanism, the grinding mechanism right side sets up the clear water room, clear water room right side bottom is provided with the outlet pipe, the grinding mechanism below sets up drying device, drying device includes the change machine, the transmission tube, the heater, the discharge gate, the drying chamber, the drying device right side is provided with wheel grinds the mixer, wheel grinds the mixer and includes the bearing, the wheel grinds the mixer middle bottom and is provided with the cooking machine, the cooking machine includes, the heater, the outlet pipe, the cooking machine bottom is provided with 400 mesh filter equipment, 400 mesh filter equipment left side is provided with 400 mesh filter discharge gate, 400 mesh filter equipment left side is provided with the reservoir, the outside of reservoir is provided with the discharge gate.
The pharmacology of the traditional Chinese medicine raw materials used in the invention is as follows:
radix aucklandiae: pungent and bitter in taste and warm in nature; enter spleen and lung meridians.
Efficacy and action: the costustoot phenol in costustoot can rebalance Th17/Treg cells in colon, mesenteric lymph nodes and spleen, and is mainly represented by reduced Th17 cell percentage and reduced Rorc, il17a mRNA expression.
Lindera root: taste and warm nature; enter lung and resolve stagnation.
Efficacy and action: relieving colonic congestion and edema, intestinal wall enlargement and mucosal ulcer injury, reducing intestinal index, regulating intestinal immune disorder, and inhibiting intestinal inflammatory mediator expression.
Mirabilite: salty, bitter and cold in nature; enter stomach and large intestine meridians.
Efficacy and action: by regulating the osmotic pressure inside and outside the cells, the water in the cells is exuded, and the local swelling and pain is reduced, and the medical origin is: "mainly used in Yi Zhi Ju" in Yun, it is indicated for heat-syndrome and internal heat-syndrome, removing intestinal stasis and resolving hard mass. "
Herba Hedyotidis Diffusae: bitter taste, cold property, anti-inflammatory and antipyretic.
Efficacy and action: the herba Hedyotidis Diffusae has antibacterial and antiinflammatory effects after entering body, contains dad alcohol and ursolic acid, and is a cereal alcohol, and can expand blood vessel of intestinal wall by reacting with intestinal cells.
Giant knotweed rhizome: slightly bitter in taste and slightly cold in nature; it enters liver and lung meridians.
Efficacy and action: the giant knotweed can effectively inhibit the differentiation of Th17 cells, and the giant knotweed can obviously reduce the dextran sodium sulfate and obviously reduce the proportion of Th17 cells in spleen and mesenteric lymph nodes, thereby relieving the nodulizing inflammation.
Herba Patriniae: bitter taste and slightly cold nature; enter large intestine meridian and liver meridian.
Efficacy and action: regulating qi and regulating blood is to smooth qi and blood of intestine and viscera stagnation, remove putrefactive lipopus, restore intestinal tract transmission function, promote repair of damaged lipofilm blood collaterals, so as to improve abdominal pain, and the method of Yi Fu Zi Patrinia in jin Kui Yao Lloyd Lv for treating intestinal abscess has the symptoms of purulence, fever, skin and wrong nails, and acute abdomen and skin, such as swelling, soft-touch, cold-dampness blood stasis, and putrefaction into purulence.
Cortex Magnoliae officinalis: bitter taste and warm nature; enter spleen meridian.
Efficacy and action: repairing intestinal barrier, reducing inflammation and oxidative stress level, regulating intestinal flora, and improving amino acid, fatty acid and bile acid metabolism.
Rhizoma smilacis glabrae: neutral nature, induce diuresis and excrete dampness, alleviate edema and alleviate pain.
Efficacy and action: poria is effective in promoting diuresis, removing dampness, invigorating spleen, calming heart, clearing heat, removing toxic substances, cooling blood, and smoothing large intestine.
Residual carbon in blood: bitter and dry, and flat; it enters liver, stomach and kidney meridians.
Efficacy and action: the residual carbon nano-fiber membrane can make the bacterial [ (7.62+/-1.87) multiplied by 104 pieces/g tissue ] content in the wound surface tissue lower than 105 pieces/g for infection of the wound surface, and the strength of the blood stopping is enhanced.
Vinegar rhizoma corydalis: bitter in taste, warm in nature, and capable of promoting blood circulation and qi circulation; it enters liver, stomach and heart meridians.
Efficacy and action: contains various isoquinoline alkaloids, and has the effects of relieving pain, promoting blood circulation, removing blood stasis, tranquilizing and allaying excitement, etc. Wherein tetrahydropalmatine has obvious sedative, hypnotic and tranquilizer effects.
Stir-baked : bitter taste and cold nature; enter liver, stomach and small intestine meridians.
Efficacy and action: can improve the contraction ability of intestinal smooth muscle, promote intestinal spasmodic contraction, and accelerate the generation and discharge of stool in intestinal tract.
Compared with the prior art, the invention has the beneficial effects that: the preparation method of the traditional Chinese medicine enema has reasonable formula, more scientific preparation process, fine liquid, small toxic and side effects and convenient preparation, and the medicinal materials have the targeted therapeutic effects of improving colorectal polyps and precancerous lesions of colorectal adenoma, aiming at local lesions of the intestinal mucosa epithelium protruding towards the intestinal cavity, recovering intestinal mucosa absorption, adjusting intestinal flora imbalance, relieving toxic and side effects, regulating intestinal epithelial cell proliferation and migration, accelerating intestinal mucosa healing, controlling inflammation.
Drawings
FIG. 1 is a schematic flow chart of the preparation process of the present invention.
Fig. 2 is a schematic diagram of the front internal structure of the present invention.
1-a first feed inlet; 2-a second feed inlet; 3-a grinding mechanism; 4-a clean water chamber; 5-a wheel mill mixer; 6-grinding wheel; 7-a water outlet pipe; 8-a heater; a 9-400 mesh filter device; filtering the material outlet with 10-400 meshes; 11-a discharge hole of the storage chamber; 12-a drying chamber; 13-turning; 14-heater, 15-300 mesh filter.
Detailed Description
The present application is described in further detail below with reference to examples. It is to be understood that the specific embodiments described herein are merely illustrative of the invention and are not limiting of the invention. It should be noted that, in the case of no conflict, the embodiments and features in the embodiments may be combined with each other.
Referring to fig. 1, the invention provides a preparation method of a traditional Chinese medicine enema, which comprises the following steps:
s1: heating herba Hedyotidis Diffusae and herba Patriniae with strong fire in a drying chamber, adhering the plants in the wall, continuously tumbling for 20 min until the surface is dark brown, cooling, and sieving to remove impurity and debris;
s2: cleaning radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, vinegar-processed rhizoma corydalis, and parched rhizoma Ligustici Chuanxiong , removing soil particles, and oven drying;
s3: taking radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, vinegar rhizoma corydalis and parched fructus Sichuan , grinding with a high-pressure grinder, discharging into a filter, and filtering with 300 mesh sieve;
s4: mixing radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, rhizoma corydalis with vinegar, parched fructus Sichuan , herba Hedyotidis Diffusae, and herba Patriniae with wheel mill mixer, mixing, discharging into a steaming furnace, boiling with clear water, steaming for 30 min, and standing;
s5: filtering the cooled medicament with a 400-mesh screen to prepare a medicament, and filtering to obtain a traditional Chinese medicine enema;
s6: the prepared traditional Chinese medicine enema is packaged, and each 100ml of the traditional Chinese medicine enema is one dose.
Further, in step S1, the mass ratio of the oldenlandia diffusa to the patrinia is: herba Hedyotidis Diffusae: herba patriniae=5 to 3. Further, in step S3, the particle diameter is: 8mm.
Further, in step S4, the mass ratio of the medicinal materials to the clear water is: medicinal materials: clear water=1 to 1.5.
Referring to fig. 2, the present invention provides a preparation device of a traditional Chinese medicine enema, which comprises the following steps:
the utility model provides a preparation facilities of traditional chinese medicine enema, includes grinding mechanism, drying mechanism, 300 mesh filter equipment, 400 mesh filter equipment, wheel grinds the mixer, the cooking machine, the grinding mechanism includes spiral grinding page, the change gear, the outside left side of grinding mechanism is provided with first feed inlet, the inside top of grinding mechanism is provided with the second feed inlet, evenly set up 300 mesh filter equipment in the middle of the grinding mechanism, the grinding mechanism right side sets up the clear water room, clear water room right side bottom is provided with the outlet pipe, the grinding mechanism below sets up drying device, drying device includes the change gear, the transmission pipe, the heater, the discharge gate, the drying chamber, the drying device right side is provided with wheel grinds the mixer, wheel grinds the mixer and includes the bearing, the wheel, wheel grinds the middle bottom of mixer and is provided with the cooking machine, the cooking machine includes, the heater, the outlet pipe, 400 mesh filter equipment left side is provided with 400 mesh filter discharge gate, 400 mesh filter equipment left side is provided with the clear water room, the left side filter equipment is provided with the discharge gate, the outside storage chamber is provided with the discharge gate.
Clinical observation:
(1) Clinical data: the inventors performed clinical observation treatment on 60 patients, 30 cases each for men and women.
(2) The treatment method comprises the following steps: the enema is inserted from rectum to colon part, and 100ml of enema is filled into colon part by enema, wherein the temperature of enema is about 39 deg.C, so as to minimize intestinal irritation, and the medicine is kept in intestine for 40 min as much as possible. Once daily, three days are a course of treatment, the treatment time is calculated according to the illness state of the patient, the patient is cured after 2-3 courses of treatment, and the patient is cured after 5-6 courses of treatment.
(3) Efficacy determination criteria efficacy criteria reference "criteria for efficacy determination of disorders in TCM".
And (3) curing: the symptoms of abdominal pain, intestinal distention, abdominal pain burning sensation, constipation, hematochezia, acid regurgitation, eructation and hiccup disappear, and normal life is restored; the effect is shown: the symptoms of abdominal pain, intestinal distention, abdominal pain burning sensation, constipation, hematochezia, acid regurgitation, eructation and hiccup are basically eliminated, and normal life is basically restored;
the method is effective: the symptoms of abdominal pain, intestinal distention, abdominal pain burning sensation, constipation, hematochezia, acid regurgitation, eructation and singultus are improved, and the pain of patients is relieved;
invalidation: the comparison of the examination before and after the treatment shows that the improvement of functions, symptoms and signs is not obvious.
(4) Clinical results: clinical cure rate = cure + significant + effective/total patient.
Embodiment one: the embodiment provides a traditional Chinese medicine enema, which comprises the following raw materials in parts by weight: 9g of costustoot, 6g of combined spicebush root, 6g of mirabilite, 5g of oldenlandia diffusa, 10g of giant knotweed, 10g of patrinia herb, 10g of magnolia officinalis, 5g of glabrous greenbrier rhizome, 5g of crinis carbonisatus, 10g of vinegar-processed rhizoma corydalis and 10g of fried seeds.
The preparation method of the traditional Chinese medicine enema comprises the following steps:
s1: heating herba Hedyotidis Diffusae and herba Patriniae with strong fire in a drying chamber, adhering the plants in the wall, continuously tumbling for 20 min until the surface is dark brown, cooling, and sieving to remove impurity and debris;
s2: cleaning radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, vinegar-processed rhizoma corydalis, and parched rhizoma Ligustici Chuanxiong , removing soil particles, and oven drying;
s3: taking radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, vinegar rhizoma corydalis and parched fructus Sichuan , grinding with a high-pressure grinder, discharging into a filter, and filtering with 300 mesh sieve;
s4: mixing radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, rhizoma corydalis with vinegar, parched fructus Sichuan , herba Hedyotidis Diffusae, and herba Patriniae with wheel mill mixer, mixing, discharging into a steaming furnace, boiling with clear water, steaming for 30 min, and standing;
s5: filtering the cooled medicament with a 400-mesh screen to prepare a medicament, and filtering to obtain a traditional Chinese medicine enema;
s6: the prepared traditional Chinese medicine enema is packaged, and each 100ml of the traditional Chinese medicine enema is one dose.
Further, in step S1, the mass ratio of the oldenlandia diffusa to the patrinia is: herba Hedyotidis Diffusae: herba patriniae=5 to 3. Further, in step S3, the particle diameter is: 8mm.
Further, in step S4, the mass ratio of the medicinal materials to the clear water is: medicinal materials: clear water=1 to 1.5.
The clinical observation method is the same as that of the example, and the clinical observation result of the example is as follows: 54 cases (90%) are clinically cured, 3 cases (5%) are effectively cured, 1 case (1.6%) is effectively cured, 2 cases (3.3%) are not cured, and the total effective rate is 96.6%.
Embodiment two: the embodiment provides a traditional Chinese medicine enema, which comprises the following raw materials in parts by weight: 12g of costustoot, 2g of combined spicebush root, 8g of mirabilite, 7g of oldenlandia diffusa, 10g of giant knotweed, 15g of patrinia herb, 20g of magnolia officinalis, 15g of glabrous greenbrier rhizome, 6g of carbonized human hair, 20g of vinegar-processed corydalis tuber and 20g of fried rhizoma .
The preparation method of the traditional Chinese medicine enema comprises the following steps:
s1: heating herba Hedyotidis Diffusae and herba Patriniae with strong fire in a drying chamber, adhering the plants in the wall, continuously tumbling for 20 min until the surface is dark brown, cooling, and sieving to remove impurity and debris;
s2: cleaning radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, vinegar-processed rhizoma corydalis, and parched rhizoma Ligustici Chuanxiong , removing soil particles, and oven drying;
s3: taking radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, vinegar rhizoma corydalis and parched fructus Sichuan , grinding with a high-pressure grinder, discharging into a filter, and filtering with 300 mesh sieve;
s4: mixing radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, rhizoma corydalis with vinegar, parched fructus Sichuan , herba Hedyotidis Diffusae, and herba Patriniae with wheel mill mixer, mixing, discharging into a steaming furnace, boiling with clear water, steaming for 30 min, and standing;
s5: filtering the cooled medicament with a 400-mesh screen to prepare a medicament, and filtering to obtain a traditional Chinese medicine enema;
s6: the prepared traditional Chinese medicine enema is packaged, and each 100ml of the traditional Chinese medicine enema is one dose.
Further, in step S1, the mass ratio of the oldenlandia diffusa to the patrinia is: herba Hedyotidis Diffusae: herba patriniae=5 to 3. Further, in step S3, the particle diameter is: 8mm.
Further, in step S4, the mass ratio of the medicinal materials to the clear water is: medicinal materials: clear water=1 to 1.5.
The clinical observations of this example were: 57 cases (95%) are clinically cured, 2 cases (3.3%) are effectively cured, 0 cases (0%) are effectively cured, 1 cases (33.33%) are not cured, and the total effective rate is 98.3%.
Embodiment III: the embodiment provides a traditional Chinese medicine enema, which comprises the following raw materials in parts by weight: 7g of costustoot, 5g of combined spicebush root, 3g of mirabilite, 8g of oldenlandia diffusa, 13g of giant knotweed, 9g of patrinia herb, 13g of magnolia officinalis, 15g of glabrous greenbrier rhizome, 5g of crinis carbonisatus, 8g of vinegar-processed rhizoma corydalis and 13g of stir-fried rhizoma .
The preparation method of the traditional Chinese medicine enema comprises the following steps:
s1: heating herba Hedyotidis Diffusae and herba Patriniae with strong fire in a drying chamber, adhering the plants in the wall, continuously tumbling for 20 min until the surface is dark brown, cooling, and sieving to remove impurity and debris;
s2: cleaning radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, vinegar-processed rhizoma corydalis, and parched rhizoma Ligustici Chuanxiong , removing soil particles, and oven drying;
s3: taking radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, vinegar rhizoma corydalis and parched fructus Sichuan , grinding with a high-pressure grinder, discharging into a filter, and filtering with 300 mesh sieve;
s4: mixing radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, rhizoma corydalis with vinegar, parched fructus Sichuan , herba Hedyotidis Diffusae, and herba Patriniae with wheel mill mixer, mixing, discharging into a steaming furnace, boiling with clear water, steaming for 30 min, and standing;
s5: filtering the cooled medicament with a 400-mesh screen to prepare a medicament, and filtering to obtain a traditional Chinese medicine enema;
s6: the prepared traditional Chinese medicine enema is packaged, and each 100ml of the traditional Chinese medicine enema is one dose.
Further, in step S1, the mass ratio of the oldenlandia diffusa to the patrinia is: herba Hedyotidis Diffusae: herba patriniae=5 to 3. Further, in step S3, the particle diameter is: 8mm.
Further, in step S4, the mass ratio of the medicinal materials to the clear water is: medicinal materials: clear water=1 to 1.5.
The clinical observation method is the same as that of the first embodiment. The clinical observations of this example were: 55 cases (91.6%) are clinically cured, 1 case (1.6%) is effectively cured, 3 case (5%) is effectively cured, 1 case (1.6%) is not effectively cured, and the total effective rate is 98.3%.
In the embodiment, after the preparation equipment is utilized to carry out primary processing on medicinal materials, in the first step, spreading hedyotis herb and patrinia herb are placed in a drying chamber to be heated by strong fire, plants are stuck in the wall, and the plants are continuously turned over for 20 minutes in a rolling way until the surfaces are dark brown, cooled and filtered to remove impurity scraps; step two, cleaning and removing soil particles of costustoot, combined spicebush root, mirabilite, giant knotweed rhizome, officinal magnolia bark, glabrous greenbrier rhizome, carbonized hair, vinegar-processed corydalis tuber and fried Sichuan seeds, and drying; thirdly, taking costustoot, combined spicebush root, mirabilite, giant knotweed rhizome, magnolia officinalis, glabrous greenbrier rhizome, crinis Carbonisatus, vinegar corydalis tuber and fried Sichuan seeds, placing a high-pressure grinding machine from a first feed inlet for grinding, discharging particles after grinding into particles, filtering with a filter of 300 meshes, discharging the particles to a drying device, and fourthly, discharging the costustoot, combined spicebush root, mirabilite, giant knotweed rhizome, magnolia officinalis, glabrous greenbrier rhizome, crinis Carbonisatus, vinegar corydalis tuber, fried Sichuan seeds, oldenlandia diffusa and herba patriniae into a rotary mill through a conveying pipe for mixing, and discharging the mixture into a cooking furnace according to the mass ratio of medicinal materials to clear water: medicinal materials: boiling clear water=1-1.5, continuing to cook for 30 minutes after boiling, standing, filtering the cooled medicament by a 400-mesh screen, discharging the cooled medicament from a discharge port of a 400-mesh filtering device to a storage chamber, wherein each 100ml of the cooled medicament is a dose, and obtaining the traditional Chinese medicine enema according to a treatment prescription, so that the obtained medicament has better effect. In conclusion, compared with western medicines, the enema has the characteristics of remarkable treatment effect and small side effect, is high in safety, and is beneficial to improvement of the illness state of patients. It will be appreciated by persons skilled in the art that the scope of the invention referred to in this application is not limited to the specific combinations of features described above, but it is intended to cover other embodiments in which any combination of features described above or equivalents thereof is possible without departing from the spirit of the invention. Such as the above-described features and technical features having similar functions (but not limited to) disclosed in the present application are replaced with each other.

Claims (8)

1. A traditional Chinese medicine enema is characterized in that: the traditional Chinese medicine enema comprises, by weight, 9g of costustoot, 6g of combined spicebush root, 6g of mirabilite, 5g of oldenlandia diffusa, 10g of polygonum cuspidatum, 10g of herba patriniae, 10g of magnolia officinalis, 5g of glabrous greenbrier rhizome, 5g of crinis carbonisatus, 10g of vinegar corydalis tuber and 10g of fried seeds.
2. A preparation method of a traditional Chinese medicine enema is characterized by comprising the following steps: the method comprises the following steps:
s1: heating herba Hedyotidis Diffusae and herba Patriniae with strong fire in a drying chamber, adhering the plants in the wall, continuously tumbling for 20 min until the surface is dark brown, cooling, and sieving to remove impurity and debris;
s2: cleaning radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, vinegar-processed rhizoma corydalis, and parched rhizoma Ligustici Chuanxiong , removing soil particles, and oven drying;
s3: taking radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, vinegar rhizoma corydalis and parched fructus Sichuan , grinding with a high-pressure grinder, discharging into a filter, and filtering with 300 mesh sieve;
s4: mixing radix aucklandiae, radix Linderae, natrii sulfas, rhizoma Polygoni Cuspidati, cortex Magnolia officinalis, rhizoma Smilacis Glabrae, crinis Carbonisatus, rhizoma corydalis with vinegar, parched fructus Sichuan , herba Hedyotidis Diffusae, and herba Patriniae with wheel mill mixer, mixing, discharging into a steaming furnace, boiling with clear water, steaming for 30 min, and standing;
s5: filtering the cooled medicament with a 400-mesh screen to prepare a medicament, and filtering to obtain a traditional Chinese medicine enema;
s6: the prepared traditional Chinese medicine enema is packaged, and each 100ml of the traditional Chinese medicine enema is one dose.
Further, in step S1, the mass ratio of the oldenlandia diffusa to the patrinia is: herba Hedyotidis Diffusae: herba patriniae=5 to 3.
Further, in step S3, the particle diameter is: 8mm.
Further, in step S4, the mass ratio of the medicinal materials to the clear water is: medicinal materials: clear water=1 to 1.5.
3. A traditional Chinese medicine enema preparation device is characterized in that: including grinding mechanism, stoving mechanism, 300 mesh filter equipment, 400 mesh filter equipment, wheel grinds the mixer, and the machine of cooking, the apotheca, grinding mechanism includes the spiral grinds the page, and the change machine, grinding mechanism outside left side is provided with first feed inlet, grinding mechanism inside top is provided with the second feed inlet, evenly set up 300 mesh filter equipment in the middle of the grinding mechanism, grinding mechanism right side sets up the clear water room, clear water room right side bottom is provided with the outlet pipe, grinding mechanism below sets up drying device, drying device includes the change machine, the transmission pipe, the heater, the discharge gate, the drying chamber, the drying device right side is provided with wheel grinds the mixer, wheel grinds the mixer and includes the bearing, the grinding wheel, wheel grinds the middle bottom of mixer and is provided with the machine of cooking, the machine of cooking includes, the heater, the outlet pipe, the machine of cooking bottom is provided with 400 mesh filter equipment, 400 mesh filter equipment left side is provided with 400 mesh filter discharge gate, 400 mesh filter equipment left side is provided with the apotheca, the outside of apotheca that sets up of apotheca in the reservoir left side.
4. A traditional Chinese medicine enema according to claim 1, wherein: the preparation method promotes secretion of glutathione enzyme, detoxifies liver and eliminates enzyme.
5. A traditional Chinese medicine enema according to claim 1, wherein: the oldenlandia diffusa contains dad alcohol and ursolic acid, which are stigma alcohol, and the stigma alcohol reacts with intestinal cells to dilate blood vessels of intestinal walls.
6. A traditional Chinese medicine enema according to claim 1, wherein: the Toosendan inhibits fungi, candida albicans, cryptococcus neoformans, microsporum ferrugineum, staphylococcus aureus and relaxes sphincters.
7. A traditional Chinese medicine enema according to claim 1, wherein: the residual carbon nanofiber membrane can enable the content of bacteria [ (7.62+/-1.87) ×104 tissues/g ] in wound tissues to be lower than 105/g for an infected wound surface.
8. A traditional Chinese medicine enema according to claim 1, wherein: the inhibition of influenza virus and orphan virus and herpes simplex virus activity in humans.
CN202211710385.1A 2022-12-29 2022-12-29 Traditional Chinese medicine enema and preparation method and equipment thereof Pending CN116251156A (en)

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