CN1162172C - Baixue-Genzhi-Changshoubao-Chinese medicine for treating leukemia and concurrently treating aplastic anemia - Google Patents

Abstract

The present invention discloses a traditional Chinese medicine for treating leukemia and concurrently treating aplastic anemia, which is mainly prepared from 9 to 15 grams of Chinese lobelia herb, 5 to 15 grams of natural indigo, 6 to 120 grams of milkvetch root, 15 to 30 grams of oldenlandia, 10 to 20 grams of flos lonicerae, 6 to 30 grams of tangshen, 4.5 to 9 grams of rhizoma, 9 to 15 grams of figwort root, 10 to 90 grams of hairyvein agrimonia herd, 15 to 60 grams of isatis root, 9 to 30 grams of rehmannia root, 6 to 12 grams of ophiopogon root, 9 to 15 grams of weeping forsythia capsule, 10 to 30 grams of imperatae rhizoma, 6 to 30 grams of tuckahoe, 4.5 to 15 grams of cortex moutan root-bark of tree peony, 6 to 60 grams of red sage root, 15 to 100 grams of heartleaf houttuynia herb, 6 to 30 grams of donkey-hide gelatin and 6 to 15 grams of rhizoma coptidis. The medicine can be prepared into various preparations, such as powder, pills, tablets, paste, etc., to be taken by oral administration. The effective rate for treating leukemia is above 90%, and the radical treatment rate is above 50% when the present invention is used for treatment for three months. Survival rate for more than five years is 80% in cured cases. The present invention also has special effects on aplastic anemia.

Description

The double Chinese medicine of controlling aplastic anemia of treatment leukemia

Technical field

The present invention relates to a kind of double Chinese medicine preparation of controlling aplastic anemia of acute and chronic leukemia for the treatment of.

Background technology

Present treatment leukemia comparatively effective method is bone marrow, umbilical blood or hematopoietic stem cell transplantation, but owing to adaptive bone marrow, umbilical blood, hematopoietic stem cell are originated limited, dependency to technology, equipment during operation is very high, and expense is up to hundreds thousand of units, thereby its application is subject to many limitations.Though adopt chemotherapy, radiotherapy can alleviate partial symptoms, can not effect a radical cure, and toxicity, side effect be big.Also have and adopt herbal treatment.Chinese patent CN95113751.4 discloses a kind of Lobatoside H that extracts from the Chinese medicine Rhizoma Bolbostematis, have the effect that kills and wounds leukaemia and inducing leukemia cell differentiation, but curative effect is not ideal enough.Chinese patent application 9915402.9 discloses a kind of leukemia of being made up of the Plumula Nelumbinis and the Radix Astragali and the Chinese medicine preparation of reversing drug resistance, has the effect of enhancing human body immunity function and certain leukemia and reversing drug resistance, but curative effect also owes desirable.Chinese patent application discloses the leukemic Chinese medicine preparation of a kind of treatment for No. 96118611.9, and its prescription reaches 66 flavor Chinese medicines, and wherein contains the national class Squama Manis that watches for animals, its practicality show belong to suspicious.At present, to aplastic anemia, there is not the specific treatment medicine yet.

Summary of the invention

Task of the present invention is to overcome the defective that above-mentioned prior art exists, provide a kind of medicinal raw material wide material sources, lower, the taking convenience of production cost, curative effect comparatively desirable and treatment leukemia that has no side effect and the pure Chinese medicinal preparation that can doublely control aplastic anemia.The traditional Chinese medical science thinks, leukemia is that evil, the heresy of positive QI-insufficiency, warm stifling or diseases caused by exogenous pathogenic factor pestilent toxicity goes into to give birth in nutrient blood, wasting QI-blood, the absurd row of forcing blood, the stagnant blood and cause a disease.Heat-clearing and toxic substances removing according to the traditional Chinese medical science, eliminating stagnation, cooling blood and dissolving purpura is eliminating evil, the pain that disappears toxin expelling, invigorating the spleen and replenishing QI, nourishing YIN and supplementing blood, clearing away heart-fire and moistening the lung, the principle of nourishing the stomach to promote the production of body fluid, the prescription of working out the present invention is as follows: Herba Lobeliae Chinensis 9-15 gram, Indigo Naturalis 5-15 gram, Radix Astragali 6-120 gram, Herba Hedyotidis Diffusae 15-30 gram, Flos Lonicerae 10-20 gram, Radix Codonopsis 6-30 gram, Rhizoma Paridis 4.5-9 gram, Radix Scrophulariae 9-15 gram, Herba Agrimoniae 10-90 gram, Radix Isatidis 15-60 gram, Radix Rehmanniae 9-30 gram, Radix Ophiopogonis, 6-12 restrained, Fructus Forsythiae 9-15 gram, Rhizoma Imperatae 10-30 gram, Poria 6-30 gram, Cortex Moutan 4.5-15 gram, Radix Salviae Miltiorrhizae 6-60 gram, Herba Houttuyniae 15-100 gram, Colla Corii Asini 6-30 gram, Rhizoma Coptidis 6-15 gram.It more than is necessary component.To patient, also should add following selectivity component: Rhizoma Anemarrhenae 6-30 gram, Gypsum Fibrosum 15-100 gram, Fructus Gardeniae 6-20 gram, Cornu Bubali 10-30 gram with high fever.Each component medical material is required section or section routinely, and roguing is mixed in proportion, and mixes pulverizing thoroughly, crosses sieve No. four, just becomes powder, the decoction of available gauze parcel, and potion on the one, early, middle and late frying in shallow oil three times taken.Also can pulverize, cross sieve No. six, add binding agent, make pill by the prescription mixed.Also can be made into dosage forms such as unguentum, tablet, capsule takes; Or be processed into injection and use.Also can be directly with being decocted in water for oral dose.Adopt the acute and chronic leukemia effective percentage of Drug therapy of the present invention to reach more than 90%; Through treatment in 3 months, radical rate reached more than 50%; Cure among the patient that survival rate reaches more than 80% more than 5 years.To treatment aplastic anemia, specially good effect is arranged equally.

The specific embodiment

Embodiment 1: take by weighing 1.5 kilograms of Herba Lobeliae Chinensis, 1 kilogram of Indigo Naturalis, 1.5 kilograms of the Radixs Astragali, 2 kilograms of Herba Hedyotidis Diffusaes, 1.5 kilograms of Flos Lonicerae, 1.5 kilograms of Radix Codonopsis, 0.7 kilogram of Rhizoma Paridis, 1 kilogram of Radix Scrophulariae, 1 kilogram of Herba Agrimoniae, 2 kilograms of Radix Isatidiss, 1.5 kilograms in the Radix Rehmanniae, 1 kilogram of Radix Ophiopogonis, 1 kilogram of Fructus Forsythiae, 1.5 kilograms of Rhizoma Imperataes, 1 kilogram in Poria, 1 kilogram of Cortex Moutan, 1 kilogram of Radix Salviae Miltiorrhizae, 1.5 kilograms of Herba Houttuyniae, 1 kilogram in Colla Corii Asini, 1 kilogram of Rhizoma Coptidis.Medical herbs in the above-mentioned medical material should be through drying, roguing etc. is pretreated.Mix, pulverize, cross No. four after the mixing thoroughly and sieve, just become powder.Adult's consumption every day is 200 grams, child's consumption every day 150 grams more than 10 years old, and consumption every day of child below 10 years old 100 grams can be packed according to the actual needs of taking medicine.Instructions about how to take medicine: bundle is decocted in water for oral dose every day 3 times.The present embodiment medicine is applicable to the treatment of acute and chronic mild phase of leukemia.

Embodiment 2: take by weighing following medicinal materials: 1.5 kilograms of Herba Lobeliae Chinensis, 1 kilogram of Indigo Naturalis, 1.5 kilograms of the Radixs Astragali, 2 kilograms of Herba Hedyotidis Diffusaes, 1.5 kilograms of Flos Lonicerae, 1.5 kilograms of Radix Codonopsis, 0.7 kilogram of Rhizoma Paridis, 1 kilogram of Radix Scrophulariae, 1 kilogram of Herba Agrimoniae, 1 kilogram of Radix Isatidis, 1 kilogram in the Radix Rehmanniae, 1 kilogram of Radix Ophiopogonis, 1 kilogram of Fructus Forsythiae, 1.5 kilograms of Rhizoma Imperataes, 1 kilogram in Poria, 1 kilogram of Cortex Moutan, 1 kilogram of Radix Salviae Miltiorrhizae, 2 kilograms of Herba Houttuyniae, 1 kilogram in Colla Corii Asini, 1 kilogram of Rhizoma Coptidis, 2 kilograms of Cornu Bubalis, 1.5 kilograms of the Rhizoma Anemarrhenaes, 1.5 kilograms of Fructus Gardeniae, 3 kilograms of Gypsum Fibrosum.Medical herbs in the above-mentioned medical material should be through drying, roguing etc. is pretreated.Above-mentioned medical material is mixed, mixes thoroughly, pulverizes, crosses No. four sieve, just become powder.Per day for adults consumption 250 grams, child's consumption every day 200 grams more than 10 years old, consumption every day of child below 10 years old 150 grams.Can pack respectively according to the actual therapeutic needs.Instructions about how to take medicine: bundle is decocted in water for oral dose every day three times.The present embodiment medicine is applicable to rescues acute leukemia hyperpyrexia phase and chronic leukemia acute transformation phase patient, and curative effect is rapid.

Case 1: Liu * *, the woman, 44 years old, nineteen ninety is suffered from chronic leukemia, and was invalid at certain well-known hospital multi-treatment, clothes embodiment 1 medicine at the beginning of 1991, every day one bag, every bag 200 grams, bundle is decocted in water for oral dose, decoction every day three times.Check hemogram behind the first quarter moon, leukocyte descends too fast, and erythrocyte is on the low side, and 300CC in time transfuses blood.Drug withdrawal continued to take medicine after having a rest two days.Once caught a cold during this time and withdraw this medicine, the medicine added with antibiotic is handled with curing cold.Continue after throwing off a cold to take medicine.Phenomenons such as anorexia, dyspepsia were arranged after January, promptly add with aid digestion class medicine.After taking medicine 2 months, enter convalescent period, the drug withdrawal in 3 days of taking medicine continuously recuperation 1 day, clinical symptom disappearance after 3 months, the drug withdrawal recuperation serve on 10 bag embodiment, 1 medicine after 20 days again, and wrap every day one, to consolidate curative effect.Can participate in housework after half a year.Visit now, be as healthy as usual.

Case 2: easily * *, man, 12 years old.Made a definite diagnosis the trouble chronic leukemia through certain well-known hospital in 1993, diagnosis and treatment are invalid, and oral ulcer and nasal cavity purulence thing had abnormal flavour with gingival hemorrhage in 1994.Through clothes embodiment 1 medicine, wrap every day 1, every bag 150 grams, and bundle is decocted in water for oral dose, decoction every day three times.After one week, the snout abnormal flavour disappears, ulcer healing.Substantially recover scarlet, sign disappearance that recover at lip, fingernail place after 60 days.After drug withdrawal recuperation January, take embodiment 1 medicine 10 bags again, every day one bag, to consolidate curative effect.In good health now.

Case 3: money * *, woman, 14 years old.Suffered from rare type chronic leukemia in 1993,,, cure not progress, go home after half a year by well-known expert's consultation of doctors in certain well-known hospital.Be unable to leave the bed at the beginning of 1994.Through clothes embodiment 2 medicines, wrap every day 1, every bag 250 grams.The 300CC that transfuses blood after 10 days, the state of an illness is stable gradually, changes clothes embodiment 1 medicine, after 10 days, transfuses blood again 1 time, continues to take embodiment 1 medicine.After 2 months, menstruation recovery is normal, and lip, fingernail place recover scarlet.Period in a medicine is advised its polyphagia Semen arachidis hypogaeae, Fructus Jujubae etc.Now attended certain department of obstetrics and gynecology system of medical university after after treatment reaches recovery from illness, and be in a good state of health in 3 months.

Case 4: yellow * *, the man, 10 years old, 1994 was acute leukemia through certain well-known hospital diagnosis, worsened on the contrary through curing the January state of an illness in many ways.Through clothes embodiment 2 medicines, wrap every day one, every bag 200 grams.Stable disease after 10 days, relatively poor because of its body constitution, 300CC transfuses blood.Change clothes embodiment 1 medicine after 15 days, wrap every day one, every bag 150 grams.Situation is better always.Change honeyed pill into after 40 days.Sign disappeared after after treatment in 3 months.Give certain hospitalize because of heavy cold after 2 years, narrate medical history in the past, doubt to acute relapse, promptly use chemotherapy, the state of an illness worsens death at once.

Case 5: money * *, woman, 12 years old.Nineteen ninety-five is an aplastic anemia through certain hospital diagnosis, cures no positive effect.Take embodiment 1 medicine in May, 1996, wrap every day 1, and every bag 150 grams are behind the first quarter moon of taking medicine, all right.Because of still the gingival hemorrhage phenomenon being arranged, add Cacumen Platycladi 8 grams every day, the Pseudobulbus Bletillae (Rhizoma Bletillae) 6 grams boil clothes.Advise it to eat Semen arachidis hypogaeae, Fructus Jujubae, egg etc. more.Sign disappears after 2 months.Recuperate after 20 days, serve on 10 bag embodiment, 1 medicine again, every day one, bag was thoroughly consolidated.Visit now, be in a good state of health, make a good academic record.

Claims (2)

1, a kind of double Chinese medicine of controlling aplastic anemia of leukemia for the treatment of is characterized in that, comprises following component:

Herba Lobeliae Chinensis 9-15 gram, Indigo Naturalis 5-15 gram, Radix Astragali 6-120 gram, Herba Hedyotidis Diffusae 15-30 gram, Flos Lonicerae 10-20 gram, Radix Codonopsis 6-30 gram, Rhizoma Paridis 4.5-9 gram, Radix Scrophulariae 9-15 gram, Herba Agrimoniae 10-90 gram, Radix Isatidis 15-60 gram, Radix Rehmanniae 9-30 gram, Radix Ophiopogonis, 6-12 restrained, Fructus Forsythiae 9-15 gram, Rhizoma Imperatae 10-30 gram, Poria 6-30 gram, Cortex Moutan 4.5-15 gram, Radix Salviae Miltiorrhizae 6-60 gram, Herba Houttuyniae 15-100 gram, Colla Corii Asini 6-.30 gram, Rhizoma Coptidis 6-15 gram.

2, according to the double Chinese medicine of controlling aplastic anemia of the described treatment leukemia of claim 1, it is characterized in that, also contain following component: Rhizoma Anemarrhenae 6-30 gram, Gypsum Fibrosum 15-100 gram, Fructus Gardeniae 6-20 gram, Cornu Bubali 10-30 gram.