CN116196257B - Anti-aging composition containing sparassis crispa extract and application thereof - Google Patents

Anti-aging composition containing sparassis crispa extract and application thereof Download PDF

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CN116196257B
CN116196257B CN202310312708.XA CN202310312708A CN116196257B CN 116196257 B CN116196257 B CN 116196257B CN 202310312708 A CN202310312708 A CN 202310312708A CN 116196257 B CN116196257 B CN 116196257B
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extract
sparassis crispa
composition containing
aging
crispa extract
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CN116196257A (en
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姜森南
马兴
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Guangzhou Shouyang Pharmaceutical Biotechnology Co ltd
Weiyimei Biotechnology Guangzhou Co ltd
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Guangzhou Shouyang Pharmaceutical Biotechnology Co ltd
Weiyimei Biotechnology Guangzhou Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

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  • Gerontology & Geriatric Medicine (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
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Abstract

The application discloses an anti-aging composition containing sparassis crispa extract and application thereof, wherein the anti-aging composition containing sparassis crispa extract comprises water, sparassis crispa extract, aloe vera extract and purslane extract; the preparation method of Sparassis crispa extract comprises the following steps: mixing Sparassis crispa and water, pulping, mixing with an extracting agent, sealing, fermenting for 1-2 d to obtain a fermented product, filtering the fermented product, and pasteurizing to obtain Sparassis crispa extract; wherein the extractant is the compound of lactobacillus plantarum, lactobacillus buchneri and corn flour; an anti-aging composition containing Sparassis crispa extract is used by adding it into anti-aging skin care product. The application prepares the Sparassis crispa extract by using a special method, so that the anti-aging composition containing the Sparassis crispa extract has better moisturizing and anti-aging effects.

Description

Anti-aging composition containing sparassis crispa extract and application thereof
Technical Field
The application relates to the technical field of cosmetics, in particular to an anti-aging composition containing sparassis crispa extract and application thereof.
Background
Along with the improvement of living standard, the requirements of people on skin care products are higher and higher, the skin care concept of natural traditional Chinese medicinal materials is very popular in recent years, and the skin care products added with the natural traditional Chinese medicinal materials are favored by consumers.
Sparassis crispa, also called Sparassis crispa, is of the genus Sparassis of the order Sparassis crispa, family Sparassis, and is a common Chinese medicinal material in the market. Because Sparassis crispa contains a large amount of beta glucan, vitamins and other components, and the mineral content is higher than that of common mushroom bacteria on the market, the sparassis crispa has pharmacological activities of bacteriostasis, lipid reduction, anti-tumor, hematopoietic function enhancement, blood pressure reduction, blood glucose reduction, anti-inflammatory, antioxidation and the like, and in recent years, sparassis crispa extract has been found to have great market potential in the field of skin care products.
Common sparassis crispa extraction methods include water extraction and alcohol extraction. Although the sparassis crispa extract prepared by the extraction method has a certain skin care effect, the active ingredients contained in the sparassis crispa extract are mostly macromolecular substances, are not easy to be absorbed by skin, and even if skin care is actively performed every day, the effect on the skin is still very slow.
Thus, there is room for improvement in the extraction method of Sparassis crispa in order to further promote the absorption of the active ingredient in Sparassis crispa by the skin.
Disclosure of Invention
In order to further improve the absorption effect of skin on Sparassis crispa extract, the application provides an anti-aging composition containing Sparassis crispa and application thereof. The inventor discovers in the research that the anti-aging composition prepared by the preparation method has better moisturizing and anti-aging effects.
In a first aspect, the application provides an anti-aging composition containing sparassis crispa extract, which adopts the following technical scheme:
an antiaging composition containing Sparassis crispa extract comprises water, sparassis crispa extract, aloe vera extract, herba Portulacae extract; the preparation method of the sparassis crispa extract comprises the following steps:
step (1): after Sparassis crispa is dried, sparassis crispa and water are mixed according to the proportion of (5-10): uniformly mixing and pulping the mixture according to the mass ratio of (100-200) to obtain a mixture;
step (2): mixing the mixture with an extractant to obtain a mixture (105 to 210): (20.2-51) and then sealing and fermenting for 1-2 d at 35-40 ℃ to obtain a fermented product;
step (3): filtering the fermented product to obtain a filtrate, and pasteurizing the filtrate at 60-65 ℃ for 30-60 min to obtain sparassis crispa extract;
wherein the extractant is lactobacillus plantarum, lactobacillus buchneri and corn meal according to (0.1-0.5): (0.1-0.5): (20-50) by mass ratio.
Preferably, the extractant is lactobacillus plantarum, lactobacillus buchneri and corn meal according to (0.1-0.2): (0.1-0.2): (40-45) and is compounded by mass proportion.
Preferably, the mixing mass ratio in the step (2) is 160: (40.2-45.4).
Preferably, the fermented product in the step (3) is crushed for 20-30 min at the temperature of 40-50 ℃ under the ultrasonic power of 120-150W and then filtered.
According to the technical scheme, fermentation is used as an extraction means of the Sparassis crispa, so that not only can the active ingredients in the Sparassis crispa be prevented from being destroyed to the greatest extent, but also the extraction rate of the active ingredients in the Sparassis crispa is further improved, and the skin care effect of the Sparassis crispa extract is further improved.
Adopts lactobacillus plantarum, lactobacillus buchneri and corn meal according to the following (0.1 to 0.5): (0.1-0.5): the extractant compounded by the mass ratio of (20-50) can further promote the extraction rate of the effective components in the Sparassis crispa, simultaneously converts the effective components in the Sparassis crispa into micromolecule substances which are more beneficial to skin absorption as much as possible, and the Sparassis crispa extract obtained by using the extractant is added into the skin care product, so that the absorption of the effective components in the skin care product by the face can be obviously promoted, the skin care effect of the skin care product is improved while the effective time of the skin care product is greatly shortened, the face roughness is effectively improved, the face texture is lightened, and the anti-aging effect is achieved.
The aloe vera extract is rich in collagen and elastin, which imparts to it certain effects of improving skin roughness and anti-aging; the purslane also called longevity grass contains rich flavonoid, vitamins, amino acid and other components, has good effects of relieving and resisting aging, and the skin care product can better lock skin moisture, and can achieve the effects of efficiently moisturizing, relieving facial lines and removing yellow by adding an anti-aging composition compounded by aloe vera extract, purslane extract and sparassia crispa extract into the skin care product.
Preferably, the anti-aging composition containing sparassis crispa extract comprises the following components in parts by weight:
sparassis crispa extract: 200-300 parts;
aloe vera extract: 2-5 parts;
purslane extract: 2-5 parts;
water: 50-100 parts.
The anti-aging composition prepared by compounding the sparassis crispa extract, the aloe vera extract and the purslane extract according to the proportion can balance the moisture, protein and lipid of epidermis, so that the epidermis is in an equilibrium state, the loss of skin moisture is reduced, the skin moisture is better locked, the skin can maintain a long-time moisture saturation state, the skin thickness is increased, the skin elasticity is increased, the facial texture is gradually lightened, the skin care efficacy of the sparassis crispa extract, the aloe vera extract and the purslane extract is further assisted, the skin tissue is gradually repaired, the vitality of the skin tissue is stimulated, and the anti-aging effect of the skin can be more remarkable.
Preferably, 2-5 parts of chamomile extract is also added into the anti-aging composition containing the sparassis crispa extract.
The golden chamomile extract contains a plurality of active ingredients such as choline, stachydrine, amino acid, flavonoid, vitamin B1, chrysanthemum lactone, stevioside, chrysanthemumol and the like, and has good antibacterial and anti-aging effects; the golden chamomile extract can cooperate with the sparassis crispa extract, the aloe vera extract and the purslane extract to promote skin metabolism, excite the skin to generate new collagen, reconstruct the collagen in the skin, and have more remarkable skin elasticity increasing effect and more remarkable anti-aging effect of the anti-aging composition.
In a second aspect, the application provides an application of an anti-aging composition containing sparassis crispa extract, which adopts the following technical scheme:
an antiaging composition containing Sparassis crispa extract is used for adding antiaging composition containing Sparassis crispa extract into antiaging skin care product.
Preferably, the adding amount of the anti-aging composition containing sparassis crispa extract is 5-10% by mass percent of the anti-aging skin care product.
According to the technical scheme, the anti-aging composition is added into the anti-aging product, so that a more efficient anti-aging effect can be achieved.
In summary, the present application includes at least one of the following beneficial technical effects:
1. the fermentation is used as an extraction means of the Sparassis crispa, so that not only can the active ingredients in the Sparassis crispa be prevented from being destroyed to the greatest extent, but also the extraction rate of the active ingredients in the Sparassis crispa is further improved, and the skin care effect of the Sparassis crispa extract is further improved.
2. Adopts lactobacillus plantarum, lactobacillus buchneri and corn meal according to the following (0.1 to 0.5): (0.1-0.5): the extractant compounded according to the proportion of (20-50) can further promote the extraction rate of the effective components in the Sparassis crispa, meanwhile, the effective components in the Sparassis crispa are converted into micromolecular substances which are more beneficial to skin absorption as much as possible, and the Sparassis crispa extract obtained by using the extractant is added into the skin care product, so that the absorption of the effective components in the skin care product by the face can be obviously promoted, the skin care effect of the skin care product is improved while the effective time of the skin care product is greatly shortened, the effects of improving the roughness of the face and relieving the lines of the face are achieved, and the anti-aging effect is achieved.
3. The anti-aging composition prepared by compounding the sparassis crispa extract, the aloe vera extract and the purslane extract according to the proportion can balance the moisture, protein and lipid of epidermis, so that the epidermis is in an equilibrium state, the loss of skin moisture is reduced, the skin moisture is better locked, the skin can maintain a long-time moisture saturation state, the skin thickness is increased, the skin elasticity is increased, the facial texture is gradually lightened, the skin care efficacy of the sparassis crispa extract, the aloe vera extract and the purslane extract is further assisted, the skin tissue is gradually repaired, the vitality of the skin tissue is stimulated, and the anti-aging effect of the skin can be more remarkable.
4. The golden chamomile extract is added into the anti-aging composition, so that skin metabolism can be promoted in a synergistic way with the sparassis crispa extract, the aloe vera extract and the purslane extract, new collagen is generated by exciting skin, the collagen in the skin is reconstructed, the skin elasticity increasing effect is more obvious, and the anti-aging effect of the anti-aging composition is more obvious.
Detailed Description
For a better description of the objects, technical solutions and advantages of the present application, the present application will be further described with reference to the following specific examples.
All raw materials and reagents which are not specifically described in the following specific embodiments are raw materials and reagents in the conventional market, and all meet the requirements of raw materials of cosmetics.
Preparation example 1
An sparassis crispa extract is prepared by the following steps:
step (1): after the sparassis crispa is dried, mixing sparassis crispa (weighted by the dried sparassis crispa) with water, and pulping to obtain a mixture;
step (2): mixing the mixture obtained in the step (1) with an extracting agent, and hermetically fermenting at 35-40 ℃ for 2d to obtain a fermented product;
step (3): centrifuging the fermented product at 1600r/min for 30min at room temperature, collecting supernatant as filtrate, and pasteurizing the filtrate at 65deg.C for 30min to obtain Sparassis crispa extract.
Wherein the extractant is compounded by lactobacillus plantarum, lactobacillus buchneri and corn flour.
Among them, lactobacillus buchneri (BNCC 189797) and lactobacillus plantarum (BNCC 336469) were purchased from beijing north narrative biotechnology institute.
Wherein the amounts of the sparassis crispa extract are shown in Table 1.
Preparation example 2
Sparassis crispa extract is different from preparation 1 in the amount of each substance.
Wherein the amounts of the sparassis crispa extract are shown in Table 1.
Preparation example 3
Sparassis crispa extract is different from preparation 1 in the amount of each substance.
Wherein the amounts of the sparassis crispa extract are shown in Table 1.
Preparation example 4
Sparassis crispa extract is different from preparation 1 in the amount of each substance.
Wherein the amounts of the sparassis crispa extract are shown in Table 1.
Preparation example 5
Sparassis crispa extract is different from preparation 1 in the amount of each substance.
Wherein the amounts of the sparassis crispa extract are shown in Table 1.
TABLE 1
Comparative preparation example 1
An extract was different from preparation 4 in that sparassis crispa was replaced with corn meal in equal amounts.
Comparative preparation example 2
An Sparassis crispa extract, unlike preparation 4, lactobacillus plantarum was replaced with Streptococcus thermophilus.
Among them, streptococcus thermophilus is commercially available.
Comparative preparation example 3
An sparassis crispa extract, unlike preparation example 4, was replaced with lactobacillus bulgaricus.
Among them, lactobacillus bulgaricus is commercially available.
Comparative preparation example 4
The sparassis crispa extract is different from preparation example 4 in that the corn meal is replaced with the purple sweet potato meal.
Wherein the purple sweet potato powder is commercially available.
Example 1
An antiaging composition containing Sparassis crispa extract comprises Sparassis crispa extract, aloe vera extract, herba Portulacae extract, and water.
Wherein, the preparation method of the anti-aging composition containing the Sparassis crispa extract comprises the following steps:
mixing the above materials at normal temperature, and stirring at 220r/min for 5min to obtain antiaging composition containing Sparassis crispa extract.
Wherein Sparassis crispa extract is from preparation 1.
Wherein the amounts of the substances are shown in Table 2.
Example 2
An antiaging composition containing Sparassis crispa extract is different from that of example 1 in the amount of each substance.
Wherein Sparassis crispa extract is from preparation 2.
Wherein the amounts of the substances are shown in Table 2.
Example 3
An antiaging composition containing Sparassis crispa extract is different from that of example 1 in the amount of each substance.
Wherein Sparassis crispa extract is from preparation example 3.
Wherein the amounts of the substances are shown in Table 2.
Example 4
An antiaging composition containing Sparassis crispa extract is different from that of example 1 in the amount of each substance.
Wherein Sparassis crispa extract is from preparation 4.
Wherein the amounts of the substances are shown in Table 2.
Example 5
An antiaging composition containing Sparassis crispa extract is different from that of example 1 in the amount of each substance.
Wherein Sparassis crispa extract is from preparation 5.
Wherein the amounts of the substances are shown in Table 2.
TABLE 2
Example 6
An antiaging composition containing Sparassis crispa extract is different from example 4 in that 2g of golden chamomile extract is also added.
Example 7
An antiaging composition containing Sparassis crispa extract is different from example 4 in that 5g of golden chamomile extract is also added.
Example 8
An anti-aging composition containing Sparassis crispa extract is different from example 7 in that chamomile extract is substituted for Cheng Maohua chrysanthemum extract.
Comparative example 1
An anti-aging composition was different from example 4 in that the extract was derived from comparative preparation 1.
Comparative example 2
An antiaging composition containing Sparassis crispa extract is different from example 4 in that Sparassis crispa extract is derived from comparative preparation 2.
Comparative example 3
An anti-aging composition containing Sparassis crispa extract was different from example 4 in that Sparassis crispa extract was derived from comparative preparation 3.
Comparative example 4
An antiaging composition containing Sparassis crispa extract is different from example 4 in that Sparassis crispa extract is derived from comparative preparation 4.
Comparative example 5
An antiaging composition containing Sparassis crispa extract is different from example 4 in that the Sparassis crispa extract is replaced with a commercially available Sparassis crispa extract by equivalent amount.
Wherein the commercial sparassis crispa extract is prepared from sparassis crispa with an extraction ratio of 1:10 by water extraction.
Comparative example 6
An antiaging composition containing Sparassis crispa extract is different from example 4 in that the Sparassis crispa extract is replaced by a commercially available water extract and corn extract compounded at a mass ratio of 10:45.
Wherein, the extraction ratio of the corn extract is 1:10 by water extraction.
Comparative example 7
An anti-aging composition containing Sparassis crispa extract is different from example 4 in that aloe vera extract is replaced with aloe ferox extract.
Comparative example 8
An anti-aging composition containing Sparassis crispa extract is different from example 4 in that purslane extract is replaced with honeysuckle extract.
Application example 1
An antiaging cream comprises 74.65g of water, 6g of glycerol, 5g of 1, 3-propylene glycol, 2.5g of squalane, 0.8g of sodium acrylate/sodium acryloyldimethyl taurate copolymer, 0.5g of phenoxyethanol and ethylhexyl glycerol mixture, 0.2g of carbomer, 0.2g of triethanolamine, 0.15g of methylparaben and 10g of antiaging composition containing Sparassis crispa extract.
Wherein the anti-aging composition containing Sparassis crispa extract was derived from example 1.
The preparation method of the anti-aging wrinkle-removing cream comprises the following steps:
step 1: adding water, glycerol, 1, 3-propylene glycol, carbomer and methylparaben into a milk pot, homogenizing for 15 minutes, heating to 85 ℃, and preserving heat for 20 minutes to obtain a first product;
step 2: cooling the first product obtained in the step 1 to 75 ℃, adding squalane and sodium acrylate/sodium acryloyldimethyl taurate copolymer, and homogenizing in vacuum for 4 minutes to obtain a second product;
step 3: and (3) cooling the second product obtained in the step (2) to 40 ℃, adding a mixture of phenoxyethanol and ethylhexyl glycerol, and uniformly mixing and stirring an anti-aging composition containing sparassis crispa extract to obtain the anti-aging wrinkle-removing cream.
Application example 2
Unlike application example 1, the amount of the antiaging composition containing Sparassis crispa extract was adjusted to 5g, and the amount of water was adjusted to 79.65g.
Application example 3
An anti-aging and wrinkle-removing essence comprises 83.85g of water, 5g of 1, 3-propylene glycol, 0.5g of 1, 2-hexanediol, 0.5g of p-hydroxyacetophenone, 0.15g of ammonium acryloyldimethyl taurate/VP copolymer and 10g of an anti-aging composition containing sparassis crispa extract.
Wherein the anti-aging composition containing Sparassis crispa extract was derived from example 1.
The preparation method of the anti-aging wrinkle-removing essence comprises the following steps of:
step one: stirring water, 1, 3-propylene glycol, 1, 2-hexanediol, p-hydroxyacetophenone and ammonium acryloyldimethyl taurate/VP copolymer together for 15 minutes, heating to 85 ℃, and preserving heat for 20 minutes to obtain a first composition;
step two: and (3) cooling the first composition obtained in the step (A) to 40 ℃, adding the anti-aging composition containing sparassis crispa extract, and uniformly mixing and stirring to obtain the anti-aging and wrinkle-removing essence.
Application example 4-application example 10
Unlike application example 1, the antiaging composition containing Sparassis crispa extract is derived from examples 2 to 8.
Comparative application example 1-comparative application example 8
Unlike application example 1, the antiaging composition containing Sparassis crispa extract was derived from comparative examples 1 to 8.
Comparative application example 9
Unlike application example 1, the antiaging composition containing Sparassis crispa extract was added in an amount of 0 and water was added in an amount of 84.65g.
Test
Test sample: the finished products of the application examples and the comparative application examples are obtained.
The tester: selecting 40-50 subjects, wherein the skin diseases are avoided, the skin is dry, and the skin moisture content is not obviously different. The testers were 190 persons total, and were divided into 19 groups of 10 persons each.
1. And (3) water supplementing effect test: reference is made to the evaluation method of QB/T4256-2011 cosmetic moisturizing efficacy evaluation guidelines.
After the subject cleans the face, the left cheek of the subject is unified by 5 x 5cm 2 The area was the test area and the corresponding right cheek area was the control area, and 0.2g of the test sample was applied uniformly to the left cheek test area using a latex finger glove, and the right side was left untreated. After adjusting the instrument according to the instructions of the skin analysis tester (CM 825-MDD of CK, germany), the same tester uses the same instrument to measure the moisture content in the test area and the control area. The initial moisture values of each test area (before sample application) were measured, then the post-application moisture values of the test area and the control area were measured 10min, 30min, and 1h after sample application, the test area was averaged according to the test group, and the control area was averaged according to all the tester data. The results are shown in Table 3.
1. Skin elasticity test: after adjusting the instrument according to the instructions of the skin analysis tester (MPA 580 of CK, germany), the same tester uses the same instrument to test the skin elasticity R2 index of the subject (the larger the measured value, the better the skin elasticity is proved). The subject's initial R2 value (before sample use) was measured, then the R2 value after 20d,40d,60d of continuous use of sample was measured, and the rate of increase of R2 value after 20d,40d,60d of continuous use of sample was calculated, the rate of increase of R2 value = [ (after sample use R2 value-before sample use R2 value)/before sample use R2 value ] ×100%, and the results were averaged, see table 4.
2. Evaluation of skin improvement effect: the eye wrinkles are obviously used as evaluation indexes, and the evaluation criteria are as follows: 1 score indicates no wrinkles;
the score 2 indicates fine wrinkles;
score 3 indicates a shallow degree of wrinkles;
score 4 indicates medium wrinkles;
score 5 indicates a severe degree of wrinkles;
10 panelists who had a history of more than 10 years in the cosmetic field were selected to constitute a panel, and the subjects were evaluated for their initial ocular wrinkle score (before using the sample) and post-use ocular wrinkle score (after 60d of continuous use of the sample), and the score results were averaged, as shown in table 4.
Table 3:
table 4:
the above test results show that application examples 1 to 10 are superior to comparative application examples 1 to 9 in both the moisturizing dimension and the improving face elasticity dimension and the wrinkle resistance dimension.
Application example 6 is different from comparative application example 1 in that comparative application example 1 does not contain an sparassis crispa extract, and the moisturizing effect, the face elasticity improving effect, and the wrinkle preventing effect of comparative application example 1 are significantly lower than application example 6, and the inventor has analyzed that sparassis crispa extract is an indispensable component of the anti-aging composition of the present application.
Application example 6 and comparative application examples 2 to 4 are different in that the extractant used is inconsistent, and the moisturizing effect, the face elasticity improving effect and the wrinkle preventing effect of comparative application examples 2 to 4 are significantly lower than those of application example 6, and the inventor analysis considers that only lactobacillus plantarum, lactobacillus buchneri and corn meal are in accordance with (0.1 to 0.5): (0.1-0.5): the extractant compounded according to the proportion of (20-50) can further promote the extraction rate of the effective components in the Sparassis crispa, meanwhile, the effective components in the Sparassis crispa are converted into micromolecular substances which are more beneficial to skin absorption as much as possible, and the Sparassis crispa extract obtained by using the extractant is added into the skin care product, so that the absorption of the effective components in the skin care product by the face can be obviously promoted, the skin care effect of the skin care product is improved while the effective time of the skin care product is greatly shortened, the effects of improving the roughness of the face and relieving the lines of the face are achieved, and the anti-aging effect is achieved.
The difference between application example 6 and comparative application examples 5-6 is that comparative application examples 5-6 respectively adopt commercial sparassis crispa extract and commercial sparassis crispa extract/corn extract to replace sparassis crispa extract extracted by a special fermentation method, and the moisturizing effect, the face elasticity improving effect and the wrinkle resisting effect of comparative application examples 5-6 are all remarkably lower than those of application example 6, and the inventor analysis proves that sparassis crispa extract prepared by adopting a special means has more excellent moisturizing and wrinkle resisting effects due to the fact that lactobacillus plantarum, lactobacillus buchneri and corn meal are adopted according to the following steps of (0.1-0.5): (0.1-0.5): the extractant compounded by the proportions of (20-50) further promotes the extraction of the effective substances in the Sparassis crispa, and simultaneously promotes the Sparassis crispa extract to be more beneficial to skin absorption, so that the effective substances in the Sparassis crispa can be maximally absorbed and utilized by the skin, thereby showing more excellent moisturizing and anti-wrinkle effects.
The difference between the application example 6 and the comparative application examples 7-8 is that the comparative application examples 7-8 respectively adopt different substances to replace aloe vera extract and purslane extract, the moisturizing effect, the face elasticity improving effect and the anti-wrinkle effect of the comparative application examples 7-8 are all obviously lower than those of the application example 6, and the inventor analyzes that the compound of the aloe vera extract, the aloe vera extract and the purslane extract prepared by the application has specificity, and the anti-aging composition prepared by compounding the three according to a specific proportion can balance the moisture, protein and lipid of the epidermis, so that the epidermis is in an equilibrium state, the loss of the skin moisture is reduced, the skin moisture is better locked, the skin can maintain a long-time moisture saturation state, the skin thickness is increased, the skin elasticity is increased, the face texture is gradually lightened, the skin tissue is gradually repaired by the aid of the skin extract, the vitality of the skin tissue is stimulated, and the anti-aging effect of the skin is more obvious.
Application example 6 and application examples 8-9 are different in that application examples 8-9 are newly added with golden chamomile extract, the moisturizing effect, the face elasticity improving effect and the anti-wrinkle effect of application examples 8-9 are all superior to application example 6 on a certain level, and the inventor analysis considers that the golden chamomile extract, the sparassia crispa extract and the aloe vera extract are added into the anti-aging composition to synergistically promote skin metabolism, excite skin to generate new collagen, reconstruct collagen in skin, the skin elasticity increasing effect is more remarkable, and the anti-aging effect of the anti-aging composition is more remarkable.
Application example 9 and application example 10 are different in that application example 10 uses Mao Hua chrysanthemum extract to replace golden chamomile extract, the effect of improving facial elasticity and anti-wrinkle effect of application example 10 is not obvious in a certain level, the inventor analyzes that the golden chamomile extract is special in selection, only the golden chamomile extract can cooperate with Sparassis crispa extract and aloe vera extract to promote skin metabolism, and the purslane extract can stimulate skin to generate new collagen, reconstruct collagen in skin, and the skin elasticity increasing effect is more obvious, and the anti-aging effect of the anti-aging composition can be more obvious.
The present embodiment is only for explanation of the present application and is not to be construed as limiting the present application, and modifications to the present embodiment, which may not creatively contribute to the present application as required by those skilled in the art after reading the present specification, are all protected by patent laws within the scope of claims of the present application.

Claims (7)

1. An anti-aging composition containing Sparassis crispa extract is characterized in that the anti-aging composition containing Sparassis crispa extract comprises water, sparassis crispa extract, aloe vera extract and purslane extract; the preparation method of the sparassis crispa extract comprises the following steps:
(1) After Sparassis crispa is dried, sparassis crispa and water are mixed according to the ratio of (5-10): uniformly mixing and pulping (100-200) in mass ratio to obtain a mixture;
(2) Mixing the mixture and the extractant (105-210): (20.2-51) and then sealing and fermenting for 1-2 d at 35-40 ℃ to obtain a fermented product;
(3) Filtering the fermented product to obtain a filtrate, and pasteurizing the filtrate at 60-65 ℃ for 30-60 min to obtain sparassis crispa extract;
wherein the extractant is lactobacillus plantarum, lactobacillus buchneri and corn meal according to (0.1-0.5): (0.1 to 0.5): (20-50) by mass ratio;
the anti-aging composition containing sparassis crispa extract comprises the following components in parts by weight:
sparassis crispa extract: 200-300 parts;
aloe vera extract: 2-5 parts;
purslane extract: 2-5 parts;
water: 50-100 parts.
2. The antiaging composition containing sparassis crispa extract according to claim 1, wherein the extractant is lactobacillus plantarum, lactobacillus buchneri, corn meal according to (0.1-0.2): (0.1 to 0.2): (40-45) by mass ratio.
3. An anti-aging composition comprising sparassis crispa extract according to claim 2, wherein the mixing mass ratio in step (2) is 160: (40.2 to 45.4).
4. The antiaging composition containing Sparassis crispa extract according to claim 1, wherein the fermented product in the step (3) is crushed at 40-50deg.C for 20-30 min under ultrasonic power of 120-150W and then filtered.
5. The antiaging composition containing Sparassis crispa extract according to claim 1, wherein 2-5 parts of Matricaria chamomilla extract is further added to the antiaging composition containing Sparassis crispa extract.
6. Use of an anti-aging composition comprising Sparassis crispa extract according to any one of claims 1 to 5, wherein the anti-aging composition comprising Sparassis crispa extract is added to an anti-aging skin care product.
7. The use of an anti-aging composition containing sparassis crispa extract according to claim 6, wherein the amount of the anti-aging composition containing sparassis crispa extract added is 5-10% by mass of the anti-aging skin care product.
CN202310312708.XA 2023-03-28 2023-03-28 Anti-aging composition containing sparassis crispa extract and application thereof Active CN116196257B (en)

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Citations (4)

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Publication number Priority date Publication date Assignee Title
KR20120087408A (en) * 2011-01-28 2012-08-07 조선대학교산학협력단 Composition for antioxidation effect comprising sparassis crispa extract
CN103864504A (en) * 2012-12-12 2014-06-18 四川省中医药科学院 Solid fermentation matrix for culturing edible and medicinal fungus, and preparation method and application thereof
CN105263965A (en) * 2013-03-15 2016-01-20 斯波根生物技术公司 Fusion proteins and methods for stimulating plant growth, protecting plants, and immobilizing bacillus spores on plants
CN110613648A (en) * 2019-10-22 2019-12-27 花安堂生物科技集团有限公司 Skin care composition capable of improving skin barrier and application thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20120087408A (en) * 2011-01-28 2012-08-07 조선대학교산학협력단 Composition for antioxidation effect comprising sparassis crispa extract
CN103864504A (en) * 2012-12-12 2014-06-18 四川省中医药科学院 Solid fermentation matrix for culturing edible and medicinal fungus, and preparation method and application thereof
CN105263965A (en) * 2013-03-15 2016-01-20 斯波根生物技术公司 Fusion proteins and methods for stimulating plant growth, protecting plants, and immobilizing bacillus spores on plants
CN110613648A (en) * 2019-10-22 2019-12-27 花安堂生物科技集团有限公司 Skin care composition capable of improving skin barrier and application thereof

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