CN116106567A

CN116106567A - Slide transfer device and sample image scanning equipment

Info

Publication number: CN116106567A
Application number: CN202211582463.4A
Authority: CN
Inventors: 林冲; 卢江涛; 闫红力
Original assignee: Shenzhen Reetoo Biotechnology Co Ltd
Current assignee: Shenzhen Reetoo Biotechnology Co Ltd
Priority date: 2022-12-09
Filing date: 2022-12-09
Publication date: 2023-05-12

Abstract

The invention discloses a slide transfer device and sample image scanning equipment, wherein the slide transfer device comprises a first track, a first transfer mechanism and a second transfer mechanism, the first track is provided with a middle position, the first transfer mechanism comprises a first accommodating structure and a second accommodating structure, the first accommodating structure is used for accommodating a first slide or a slide basket loaded with the first slide, the second accommodating structure is used for accommodating a second slide or a slide basket loaded with the second slide, the first transfer mechanism is used for moving along the first track so as to transfer the first accommodating structure and the second accommodating structure to the middle position, and the second transfer mechanism is at least used for transferring the first slide and/or the second slide positioned at the middle position to a scanning position of the sample image scanning equipment for scanning. According to the invention, only one first transfer mechanism and one first track are arranged, so that the transfer of the first slide and the second slide can be realized, the structure is compact, the cost is saved, and the machine miniaturization is facilitated.

Description

Slide transfer device and sample image scanning equipment

Technical Field

The invention relates to the technical field of medical equipment, in particular to a slide transfer device and sample image scanning equipment.

Background

The sample image scanning equipment is equipment for carrying out automatic microscopic examination on a slide to be detected after the slide is made, and is used for assisting in diagnosing diseases by shooting a sample image on the slide through a microscope and obtaining a detection result through system analysis and judgment. Microscopy is short for microscopic examination, which is to take a sample of a specimen to be examined, slide the slide of which is made into slices, and observe, analyze and judge the sample under a microscope. Wherein human excreta, secretion, abscisic cells or tissues, animal tissues, even plant cells, etc. can be used as the object of microscopic examination, and the common scope is to assist in diagnosing diseases.

The transportation of abnormal slides such as emergency treatment in traditional sample image scanning equipment generally needs to set up transport module alone, and independent of each other with the transport module of conventional slide, and the setting up of a plurality of transport modules leads to reading appearance volume increase, is unfavorable for the machine miniaturization.

Disclosure of Invention

In view of the above, the present invention provides a slide transfer device and a sample image scanning apparatus.

A first aspect of the present invention provides a slide transfer device comprising:

a first track having a neutral index;

a first transfer mechanism comprising a first containment structure for containing a first slide or a slide basket loaded with a first slide and a second containment structure for containing a second slide or a slide basket loaded with a second slide, the first transfer mechanism being for moving along the first track to transfer the first containment structure and the second containment structure to the transfer position;

and the second transfer mechanism is at least used for transferring the first slide and/or the second slide positioned in the transfer position to the scanning position of the sample image scanning device for scanning.

A second aspect of the invention provides a sample image scanning apparatus comprising a slide transfer device as described above.

According to the technical scheme, the slide transferring device is provided with only one first transferring mechanism and the first track, so that the transfer of the first slide and the transfer of the second slide can be realized, the structure is compact, the space is reasonably utilized, the volume is reduced, the cost is saved, and the machine miniaturization is facilitated.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for the description of the embodiments will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings may be obtained by those skilled in the art without the inventive effort.

Fig. 1 is a schematic structural diagram of a sample image scanning apparatus according to an embodiment of the present invention.

Fig. 2 is a schematic diagram of a hidden part structure of a sample image scanning apparatus according to an embodiment of the present invention.

Fig. 3 is a block diagram of a moving track of a slide basket according to an embodiment of the present invention.

Fig. 4 is a schematic structural diagram of a first transfer mechanism, a sample feeding mechanism and a sample discharging mechanism according to an embodiment of the present invention.

Fig. 5 is an enlarged partial schematic view of a first transfer mechanism according to an embodiment of the present invention.

Fig. 6 is a schematic structural diagram of a second transfer mechanism according to an embodiment of the present invention.

FIG. 7 is a schematic diagram of a cache module according to an embodiment of the present invention.

Fig. 8 is a schematic structural diagram of a conveying assembly according to an embodiment of the present invention.

In the figure: 100. a slide transfer device; 10. a first track; 11. indexing; 12. taking and placing; 13. recovering the position; 20. a first transfer mechanism; 21. a first receiving structure; 211. a first pushing section; 212. a second pushing part; 213. a first accommodation site; 22. a second receiving structure; 221. a first accommodating groove; 222. a second accommodating groove; 23. a first driving module; 30. a second transfer mechanism; 31. a first transfer assembly; 311. an X-axis driving module; 312. a Y-axis driving module; 313. a Z-axis driving module; 314. mechanical clamping jaws; 32. a second transfer assembly; 321. a cache component; 321a, a buffer seat; 321b, a second driving module; 3211. caching bits; 322. a transport assembly; 322a, a transport structure; 322b, a third driving module; 40. a controller; 50. a housing; 51. a taking and placing port; 60. an interaction module; 70. a sample injection mechanism; 71. a second track; 72. a first pushing assembly; 80. a sample discharging mechanism; 81. a third track; 82. a second pushing assembly; 1000. a sample image scanning device; 200. a scanning device; 201. scanning the bits; 300. a slide unloading device; 2000. slide basket.

Detailed Description

The following description of the embodiments of the present invention will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are some, but not all embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

It is also to be understood that the terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used in this specification and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.

It should be further understood that the term "and/or" as used in the present specification and the appended claims refers to any and all possible combinations of one or more of the associated listed items, and includes such combinations.

Therefore, the embodiment of the invention provides the slide transferring device and the sample image scanning equipment, which can realize the transfer of the first slide and the transfer of the second slide, have compact structure, reasonably utilize space, reduce the volume, save the cost and be beneficial to machine miniaturization.

Referring to fig. 1 and 2, an embodiment of the present invention proposes a sample image scanning apparatus 1000, including a slide transferring device 100 and a scanning device 200, where the scanning device 200 is a microscope assembly capable of performing microscopic examination on a slide, and is used to scan the slide transferred to a scanning position 201 by the slide transferring device 100 to obtain sample image information.

In some embodiments, as shown in fig. 2, the specimen image scanning apparatus 1000 further includes a slide unloading device 300, the slide unloading device 300 being for storing slides that have been scanned. In this embodiment, the slide unloading device 300 may be mounted on a front housing or a side housing in the left-right direction of the sample image scanning apparatus 1000 by adopting a drawer structure, so that a slide can be unloaded from the slide unloading device 300 after being moved out of the sample image scanning apparatus 1000, and by setting the slide unloading device 300, the fed slide basket 2000 does not need to wait for the completion of the slide scanning in situ, and the scanned slide is stored by the slide unloading device 300, so that the waiting time of the slide basket 2000 is saved, the slide basket 2000 can be prevented from being polluted by the oil, the slide basket 2000 can be reused conveniently, and the working efficiency is improved.

Referring to fig. 1-5, an embodiment of the present invention also proposes a slide transfer device 100 for a sample image scanning apparatus 1000, the slide transfer device 100 comprising a first rail 10, a first transfer mechanism 20 and a second transfer mechanism 30, the first rail 10 having an intermediate index 11, the first transfer mechanism 20 comprising a first receiving structure 21 and a second receiving structure 22, the first receiving structure 21 being for receiving a first slide or a slide basket 2000 loaded with a first slide, the second receiving structure 22 being for receiving a second slide or a slide basket 2000 loaded with a second slide, the first transfer mechanism 20 being for moving along the first rail 10 to transfer the first receiving structure 21 and the second receiving structure 22 to the intermediate index 11, the second transfer mechanism 30 being at least for transferring the first slide and/or the second slide at the intermediate index 11 to a scanning position 201 of the sample image scanning apparatus 1000 for scanning.

According to the slide transfer device 100 provided by the embodiment of the invention, the first slide can be a conventional slide, the second slide can be a first review slide which needs to be subjected to review after emergency slides and/or abnormal scanning, and the slide transfer device 100 is only provided with one transfer mechanism and the first track 10, so that the transfer of the first slide can be realized, and the transfer of the second slide can be realized.

In some embodiments, as shown in fig. 2-3, the first slide comprises a conventional slide, the second slide comprises an emergency slide, the slide transfer device 100 further comprises a controller 40, the controller 40 for controlling the first transfer mechanism 20 to move along the first track 10 to transfer the conventional slide to the intermediate position 11 and for controlling the second transfer mechanism 30 to transfer the conventional slide at the intermediate position 11 to the scanning position 201 as the conventional slide is advanced; the controller 40 is further configured to control the first transfer mechanism 20 to move along the first rail 10 to transfer the emergency slide to the intermediate position 11 and to control the second transfer mechanism 30 to transfer the emergency slide at the intermediate position 11 to the scanning position 201 when an emergency instruction is received. In this embodiment, the first transfer mechanism 20 is controlled by the controller 40 to perform conventional slide transfer and emergency slide transfer.

In some embodiments, as shown in fig. 1-3, the first track 10 is further provided with a pick-and-place 12, where the pick-and-place 12 is used for placing an emergency slide by a user, and the controller 40 is used for controlling the first transfer mechanism 20 to move to the pick-and-place 12 preferentially when receiving an emergency instruction, so that the user can control the first transfer mechanism 20 to move to the transfer position 11 after placing the emergency slide to the second accommodating structure 22 through the pick-and-place 12. In this embodiment, a pick-and-place station 12 is provided on the first rail 10 to facilitate placement of an emergency slide into the first transfer mechanism 20 for pushing into the sample image scanning device 1000.

In some embodiments, as shown in fig. 2-3, the first slide comprises a conventional slide, the second slide comprises a first review slide, the slide transfer device 100 further comprises a controller 40, the controller 40 for controlling the first transfer mechanism 20 to move along the first track 10 to transfer the conventional slide to the intermediate index 11 and for controlling the second transfer mechanism 30 to transfer the conventional slide at the intermediate index 11 to the scanning position 201 as the conventional slide is advanced; the controller 40 is further configured to control the second transfer mechanism 30 to transfer the first review slide at the corresponding position in the slide unloading device 300 of the sample image scanning apparatus 1000 to the second accommodating structure 22 located at the middle position 11 when receiving the review push instruction, and control the first transfer mechanism 20 to move out of the middle position 11, so that the user can take the first review slide for manual review or for automatic review on other apparatuses. In this embodiment, the first transfer mechanism 20 can be controlled by the controller 40 to perform transfer of the conventional slide and to perform transfer of the first review slide.

In some embodiments, the first housing structure 21 or the second housing structure 22 is further configured to house a second review slide, and the controller 40 is further configured to control the first transfer mechanism 20 to move along the first track 10 when receiving a review push-in instruction, to transfer the second review slide entered by the user to the middle position 11, and to control the second transfer mechanism 30 to transfer the second review slide at the middle position 11 to the scanning position 201. For example, the embodiment of the application may also not be provided with the second review slide, that is, the sample image scanning device of the application is not used for automatically reading the review slide, but performs manual review after manually taking out the first review slide or performs automatic review on other devices.

In some usage scenarios, the slide that needs to be taken out for manual review after the scanning is abnormal is the first review slide, and when the scanning is abnormal, the same sample is found according to the sample code of the scanning abnormality, a new slide coated with the same sample is prepared by slide making, and the slide that is sent into the sample image scanning device 1000 for microscopic review by the scanning device 200 is the second review slide. When the slide scanning is abnormal, the user can choose to take out for manual recheck, or choose to prepare the slide coated with the same sample again and send the slide to the sample image scanning device 1000 for machine recheck through the scanning device 200, when the slide coated with the same sample is selected to be rechecked, the second rechecked slide can be placed in the slide basket of the first accommodating structure 21, or can be placed in the second accommodating structure 22, since the first rechecked slide is a slide which is scanned abnormally after the mirror inspection and needs to be taken out for recheck, the first rechecked slide is dripped with mirror oil, in order to avoid the mirror oil from polluting the second rechecked slide after the rechecked slide, the placement position of the first rechecked slide needs to be separated from the second rechecked slide, and the second accommodating structure 22 comprises a first accommodating groove 221 and a second accommodating groove 222, and the second rechecked slide is placed in the first accommodating groove 222.

In some embodiments, as shown in fig. 1-3, the first track 10 is further provided with a pick-and-place 12, where the pick-and-place 12 is used for a user to take out the first review slide, and when the second review slide performs sample injection through the first accommodating groove 222 in the second accommodating structure 22, the pick-and-place 12 is also used for placing the second review slide; the controller 40 is used for controlling the second transferring mechanism 30 to transfer the first review slide at the corresponding position in the sample image scanning device 1000 to the second accommodating structure 22 at the middle position 11 when receiving the review push instruction, and controlling the first transferring mechanism 20 to move to the picking and placing position 12, so that the user can take the first review slide for manual review or for automatic review on other devices through the picking and placing position 12.

In some embodiments, the controller 40 is configured to control the first transferring mechanism 20 to move along the first track 10 to the pick-and-place position 12 when receiving the review push-in instruction, so that the user can insert the second review slide into the first receiving groove 222 or the first receiving structure 21 of the second receiving structure 22 through the pick-and-place position 12 and then control the first transferring mechanism 20 to move to the transferring position 11. In this embodiment, a pick-and-place location 12 is provided on the first rail 10 to facilitate the removal of a first review slide or the placement of a second review slide.

It can be understood that the second slide provided in the embodiment of the present invention may include only the emergency slide, or only the first review slide, or of course, may also include the emergency slide and the review slide, where the taking and placing positions 12 for taking out the first review slide, placing in the second review slide, and placing in the emergency slide are the same position, so as to improve the space utilization.

In some embodiments, as shown in fig. 3, the first receiving structure 21 is configured to receive a slide basket 2000 loaded with a first type of slide, the first rail 10 is further provided with a recovery station 13, and the controller 40 is further configured to control the first transfer mechanism 20 to transfer an empty slide basket 2000 to the recovery station 13 when the second transfer mechanism 30 removes all slides within the slide basket 2000 positioned in the index 11. In this embodiment, after the slide is taken out completely, the empty slide basket 2000 can be moved out, and the slide after the completion of scanning is stored by the slide unloading device 300 without waiting for the completion of scanning in situ, so that the waiting time of the slide basket 2000 is saved, the slide basket 2000 can be prevented from being polluted by the oil, the slide basket 2000 can be reused conveniently, and the working efficiency is improved.

In some embodiments, the second slide includes an emergency slide and/or a first review slide, the first housing structure 21 or the second housing structure 22 is further configured to house a second review slide, as shown in fig. 1 and 2, the slide transfer device 100 further includes an interaction module 60 and a controller 40, the interaction module 60 is at least configured to be operated by a user to generate an emergency instruction and/or a review push instruction, and the controller 40 is communicatively connected to the interaction module 60 to control the first transfer mechanism 20 to cooperate with the second transfer mechanism 30 to transfer the slide according to the emergency instruction or the review push instruction generated by the interaction module.

Illustratively, the interaction module 60 includes a display screen, which may be a touch screen, for a user to generate input instructions by touching corresponding marks of the touch screen, or by a combination of the display screen and control buttons for the user to generate input instructions by clicking the control buttons, including emergency instructions, review push instructions, and review push instructions.

In some use scenarios, wherein the emergency instructions include an emergency push instruction and an emergency push instruction, the controller 40 is configured to control the first transfer mechanism 20 to move out of the index 11 to the pick-and-place position 12 for the emergency slide to be placed into the second receiving structure 22 when the emergency push instruction is received, and to control the first transfer mechanism 20 to transfer the emergency slide to the index 11 and the second transfer mechanism 30 to transfer the emergency slide from the index 11 to the scan position 201 when the emergency push instruction is received. In this embodiment, the controller 40 can control the first transfer mechanism 20 and the second transfer mechanism 30 to perform priority treatment on the emergency slide when the emergency slide needs to be inserted, so that the detection efficiency is high.

When the controller receives the emergency instruction, the controller preferably schedules the required resources for emergency sample injection, for example, obtains the resources of the first transfer mechanism 20 and the second transfer mechanism 30, and controls the first transfer mechanism 20 and the second transfer mechanism 30 to execute corresponding working states so as to complete sample injection of emergency slides.

In some usage scenarios, the controller 40 is configured to, when receiving the review push command, control the second transfer mechanism 30 to transfer the first review slide at the corresponding position in the sample image scanning apparatus 1000 into the second receiving structure 22 located at the middle index 11, and control the first transfer mechanism 20 to transport the first review slide from the middle index 11 to the pick-and-place position 12 for the user to manually review the first review slide from the pick-and-place position 12 or to automatically read the slide on another apparatus. In this embodiment, when the slide is abnormally scanned and needs to be taken out, the controller 40 controls the first transfer mechanism 20 and the second transfer mechanism 30 to cooperate to transfer the first review slide to the taking and placing position 12, so that the user can take out the slide for manual review or automatically read the slide on other devices.

When the controller receives the review push command, the controller preferentially schedules the required resources of the first review slide, for example, the resources of the first transfer mechanism 20 and the second transfer mechanism 30 are acquired, and controls the first transfer mechanism 20 and the second transfer mechanism 30 to execute corresponding working states, so as to complete the sample output of the first review slide.

In some usage scenarios, the controller 40 is configured to control the first transfer mechanism 20 to move out of the index 11 to the pick-and-place position 12 when receiving the review push-in command, for the second review slide to be placed into the first receiving groove 222 or the first receiving structure 21 of the second receiving structure 22 through the pick-and-place position 12, and to control the second transfer mechanism 30 to transfer the second review slide to the scanning position 201. In this embodiment, the second review slide is specifically a slide in which, when the scan is abnormal, a new slide coated with the same sample is found and prepared by slide preparation according to the sample code of the scan abnormality, and sent into the sample image scanning device 1000 for microscopic examination by the scanning device 200, and the first transfer mechanism 20 and the second transfer mechanism 30 are controlled by the controller 40 to cooperate to transfer the second review slide to the scan position 201 for scanning, so as to obtain the review result of the same sample.

When the controller receives the re-diagnosis push command, the controller preferentially schedules the required resources of the second re-diagnosis slide sample, for example, obtains the resources of the first transfer mechanism 20 and the second transfer mechanism 30, and controls the first transfer mechanism 20 and the second transfer mechanism 30 to execute corresponding working states so as to complete sample injection of the second re-diagnosis slide.

The controller 40 provided in the embodiment of the present invention may adopt the existing PLC programmable logic controller 40, DDC direct digital controller 40, or single chip microcomputer control system, etc. to implement the above control process.

In some embodiments, as shown in fig. 3 and 4, the slide transfer device 100 further includes a sample introduction mechanism 70, the sample introduction mechanism 70 including a second rail 71 and a first pushing assembly 72, the second rail 71 being connected to the first rail 10, the first pushing assembly 72 being configured to drive the slide basket 2000 loaded with the first slide along the second rail 71 to push the slide basket 2000 to the first rail 10, wherein the second rail 71 is disposed perpendicular to the first rail 10, and/or the second rail 71 being configured to splice with a pusher, the pusher being configured to transfer the slide basket 2000 loaded with the first slide to the second rail 71. In this embodiment, the second rail 71 may be spliced with the slide pusher to realize automatic feeding of the slide basket 2000 loaded with slides, but of course, the second rail 71 may be directly put on the slide basket 2000 loaded with slides to the second rail 71 by manual work without being spliced with the slide pusher.

In some embodiments, as shown in fig. 3 and 4, the first rail 10 also has a recovery station 13, and the first transfer mechanism 20 is also used to transfer the empty slide basket 2000 to the recovery station 13; the slide transfer device 100 further includes a sample ejection mechanism 80, the sample ejection mechanism 80 includes a third rail 81 and a second pushing assembly 82, the recovery site 13 is in butt joint with the third rail 81, and the second pushing assembly 82 is used for pushing the empty slide basket 2000 located at the recovery site 13 to the third rail 81. In this embodiment, the third rail 81 is used for placing the empty slide basket 2000, the second rail 71 and the third rail 81 are perpendicular to the first rail 10, and the second rail 71 and the third rail 81 are arranged on the same side of the first rail 10 in parallel, so that the first rail 10, the second rail 71 and the third rail 81 enclose to form a U-shaped structure, thereby shortening the moving path of the slide basket 2000, improving the working efficiency, having a compact structure and being beneficial to miniaturization of equipment.

Of course, the recycling position 13 may also be spliced with a recycling device of an external apparatus, so that the recycling device of the external apparatus receives the empty slide basket 2000, or alternatively, the recycling position 13 is spliced with a slide pusher, and the slide pusher is used for transferring the prepared slide into the empty slide basket 2000 and sending the slide basket 2000 loaded with the slide into the sample image scanning apparatus 1000, so as to realize recycling of the slide basket 2000.

In some embodiments, as shown in fig. 5, the second slide comprises an emergency slide and/or a first review slide, and the second receiving structure 22 comprises at least one first receiving slot 221, the first receiving slot 221 for receiving the emergency slide; and/or the second receiving structure 22 includes at least one second receiving slot 222, the second receiving slot 222 being configured to receive the first review slide. In this embodiment, the first accommodating groove 221 is configured to be used for accommodating an emergency treatment slide, and the second accommodating groove 222 is configured to be used for accommodating a first review slide, so as to avoid confusion between the emergency treatment slide and the first review slide, and avoid the emergency treatment slide from being polluted by the oil on the first review slide, and the first review slide is a slide for a user to take out for manual review or for automatic review on other devices.

In some embodiments, as shown in fig. 5, the second accommodating structure 22 includes a first accommodating groove 221 and a second accommodating groove 222, where the first accommodating groove 221 and the second accommodating groove 222 are separately disposed to leave a preset distance for a user to take and place a slide, so as to facilitate the user to operate.

In some embodiments, as shown in fig. 1 and 5, the slide transferring device 100 is provided with a cover shell 50 covered on the first track 10, and a picking and placing port 51 corresponding to the picking and placing position 12 is provided on the cover shell 50, wherein the cross section area of the picking and placing port 51 is smaller than the interval between the first accommodating groove 221 and the second accommodating groove 222, so that a user can take out or put in a slide at a time, for example, only one emergency slide can be put in or one first re-diagnosis slide can be taken out or one second re-diagnosis slide can be put in at a time, and slide confusion can be avoided.

In some embodiments, as shown in fig. 2-5, the first track 10 is further provided with a pick-and-place position 12, where the pick-and-place position 12 is used for placing an emergency slide and/or picking and placing a first review slide for a user; the slide transfer device 100 further includes a controller 40, the controller 40 being configured to control the first transfer mechanism 20 to move a first distance along the first track 10 such that the position of the first receiving slot 221 corresponds to the picking and placing position 12, and/or the controller 40 being configured to control the first transfer mechanism 20 to move a second distance along the first track 10 such that the position of the second receiving slot 222 corresponds to the picking and placing position 12. In this embodiment, the first accommodating groove 221 and the second accommodating groove 222 are arranged at intervals along the extending direction of the first track 10, so that the distance between the first accommodating groove 221 and the picking and placing position 12 is different from the distance between the second accommodating groove 222 and the picking and placing position 12, the distance from the first accommodating groove moving to the picking and placing position 12 is a first distance, the distance from the second accommodating groove moving to the picking and placing position 12 is a second distance, the first transferring mechanism 20 provides driving force through the motor, and the moving distance of the first transferring mechanism 20 can be controlled through the moving step control of the motor, so that the first accommodating groove 221 or the second accommodating groove 222 is driven to correspond to the picking and placing position 12 according to different instructions.

In some embodiments, as shown in fig. 4 and 5, the first accommodating structure 21 is configured to accommodate a slide basket 2000 loaded with a first type of slide, the first accommodating structure 21 includes a first pushing portion 211 and a second pushing portion 212, the first pushing portion 211 and the second pushing portion 212 are spaced apart along an extending direction of the first rail 10, a first accommodating position 213 accommodating the slide basket 2000 is formed by enclosing the first pushing portion 211 and the second pushing portion 212, the first pushing portion 211 is configured to push the slide basket 2000 when the first transfer mechanism 20 moves to the transfer position 11, and the second pushing portion 212 is configured to push the slide basket 2000 when the first transfer mechanism 20 moves out of the transfer position 11. 2000 in the present embodiment, the first pushing part 211 is for abutting one side of the slide basket 2000 to push the slide basket 2000 to the middle index 11, and the second pushing part 212 is for abutting the other side of the slide basket 2000 to push the slide basket 2000 out of the middle index 11.

It should be noted that, the first accommodating structure and the second accommodating structure are not limited to the two mechanisms that are independently arranged, and may be two accommodating sections in the same mechanism, for example, the first accommodating structure and the second accommodating structure are two sets of slots that are arranged at intervals on the same bearing seat, and each set of slots includes at least one slot for accommodating a slide. One group of clamping groove sets is a first accommodating structure and is used for accommodating a first slide, and the other group of clamping groove sets is a second accommodating structure and is used for accommodating a second slide.

In some embodiments, as shown in fig. 4 and 5, the first transferring mechanism 20 further includes a first driving module 23, at least one of the first accommodating structure 21 and the second accommodating structure 22 is connected to the first driving module 23, and the first driving module 23 is used for driving the first accommodating structure 21 and the second accommodating structure 22 to move synchronously along the first track 10. The first driving module 23 includes a motor and a transmission assembly, the transmission assembly is connected with the pushing structure, and the motor is used for driving the transmission assembly to drive the first accommodating structure 21 to move along the first track 10, so as to facilitate the transfer of the slide basket 2000. The transmission assembly can adopt any one of a belt transmission mechanism, a chain transmission mechanism, a gear rack transmission mechanism or a screw rod transmission mechanism, so as to drive the first accommodating structure 21 to push the slide basket 2000 to move.

In some embodiments, as shown in fig. 6 and 7, the slide has a vertical state at the time of sampling and a horizontal state at the time of scanning, the second transfer mechanism 30 includes a first transfer member 31 and a second transfer member 32, the first transfer member 31 is used for transferring the slide in the vertical state at the middle index 11 to the second transfer member 32, the second transfer member 32 has a buffer seat 321a, the buffer seat 321a is provided with a buffer position 3211 for placing the slide, the buffer seat 321a is capable of being flipped so that the slide in the buffer position 3211 is switched between the vertical state and the horizontal state, and the second transfer member 32 is also used for transferring the slide in the horizontal state between the buffer position 3211 and the scanning position 201.

In some embodiments, as shown in fig. 6, the first transferring assembly 31 includes an X-axis driving module 311, a Y-axis driving module 312, a Z-axis driving module 313, and a mechanical gripper 314, where the X-axis driving module 311 is used to drive the mechanical gripper 314 to move along an X-axis direction, the X-axis direction is a left-right direction of the sample image scanning apparatus 1000, the Z-axis driving module 313 is used to drive the mechanical gripper 314 to move along a Z-axis direction, the Z-axis direction is a height direction of the sample image scanning apparatus 1000, the Y-axis driving module 312 is used to drive the mechanical gripper 314 to move along a Y-axis direction, the Y-axis direction is a front-back direction of the sample image scanning apparatus 1000, and the mechanical gripper 314 is used to grip or release a slide to transfer the slide. In this embodiment, by the arrangement of the X-axis driving module 311, the Y-axis driving module 312 and the Z-axis driving module 313, the mechanical clamping jaw 314 can be driven to move in three-dimensional space, so as to facilitate the transfer between a plurality of positions on the slide.

Illustratively, the X-axis driving module 311, the Y-axis driving module 312 and the Z-axis driving module 313 may adopt a driving mode that a driving member is combined with a transmission structure, the driving member of the Y-axis driving module 312 is connected to the X-axis driving module 311 through the transmission structure, the driving member of the X-axis driving module 311 is connected to the Z-axis driving module 313 through the transmission structure, and the driving member of the Z-axis driving module 313 is connected to the mechanical clamping jaw 314 through the transmission structure, so as to realize the movement of the mechanical clamping jaw 314 in the X-axis, the Y-axis and the Z-axis directions. The driving members of the X-axis driving module 311, the Y-axis driving module 312 and the Z-axis driving module 313 may be driving motors or other devices capable of providing driving force, and the transmission structure may be any one of a belt transmission mechanism, a chain transmission mechanism, a rack and pinion transmission mechanism or a screw transmission mechanism, so as to drive the mechanical clamping jaw 314 to move.

In some embodiments, as shown in fig. 7 and 8, the second transfer assembly 32 includes a buffer assembly 321 and a transport assembly 322, the buffer assembly 321 includes a buffer seat 321a and a second driving module 321b for driving the buffer seat 321a to rotate, so that slides on the buffer station 3211 are switched between a vertical state and a horizontal state, and the transport assembly 322 includes a transport structure 322a for transferring slides and a third driving module 322b for driving the transport structure 322a to move, so as to transfer slides in the horizontal state between the buffer station 3211 and the scan station 201. In this embodiment, the first transferring assembly 31 is used for transferring a slide in a vertical state from the middle to the buffer position 3211, the second transferring assembly 32 drives the buffer seat 321a to rotate through the second driving module 321b, so that the slide on the buffer position 3211 is converted from a vertical state to a horizontal state, then drives the conveying structure 322a to move through the third driving module 322b, so that the slide in the horizontal state to be scanned is transferred to the scanning position 201 for scanning, and after the scanning is completed, the third driving module 322b drives the conveying structure 322a to remove the slide from the scanning position 201 to the buffer position 3211, and then drives the buffer seat 321a to rotate through the second driving module 321b, so that the slide on the buffer position 3211 is converted from the horizontal state to the vertical state, so that the slide in the vertical state is transferred to the slide unloading device 300 by the first transferring mechanism.

The second driving module 321b may drive the pulley to rotate by using a motor synchronous belt, and the pulley is connected to the buffer seat 321a through a rotation shaft to drive the buffer seat 321a to turn over.

The third driving module 322b may drive the slide block to move along the slide rail by a motor through a transmission structure to drive the conveying structure 322a connected to the slide block into or out of the slide. The transmission structure may employ any one of a belt transmission mechanism, a chain transmission mechanism, a rack and pinion transmission mechanism, or a screw transmission mechanism to realize the movement of the driving conveyance structure 322 a.

While the invention has been described with reference to certain preferred embodiments, it will be understood by those skilled in the art that various changes and substitutions of equivalents may be made and equivalents will be apparent to those skilled in the art without departing from the scope of the invention. Therefore, the protection scope of the invention is subject to the protection scope of the claims.

Claims

1. A slide transfer device for a sample image scanning apparatus, comprising:

a first track having a neutral index;

2. The slide transfer device of claim 1, wherein the first slide comprises a conventional slide and the second slide comprises an emergency slide, the slide transfer device further comprising:

a controller for controlling the first transfer mechanism to move along the first rail to transfer the regular slide to the index when the regular slide is sampled, and controlling the second transfer mechanism to transfer the regular slide located at the index to the scanning position;

the controller is also used for controlling the first transfer mechanism to move along the first track when an emergency instruction is received so as to transfer the emergency slide to the middle position, and controlling the second transfer mechanism to transfer the emergency slide positioned in the middle position to the scanning position.

3. The slide transfer device of claim 2, wherein the first rail is further provided with a pick-and-place position for a user to place the emergency slide;

the controller is used for controlling the first transfer mechanism to move to the picking and placing position preferentially when an emergency instruction is received, so that a user can control the first transfer mechanism to move to the transfer position after placing an emergency slide to the second accommodating structure through the picking and placing position.

4. The slide transfer device of claim 1, wherein the first slide comprises a conventional slide and the second slide comprises a first review slide, the slide transfer device further comprising:

the controller is further used for controlling the second transfer mechanism to transfer the first review slide at the corresponding position in the sample image scanning device to the second accommodating structure positioned at the transfer position when receiving the review push-out instruction, and controlling the first transfer mechanism to move out of the transfer position so as to enable a user to take out the first review slide.

5. The slide transfer device of claim 4 wherein the first rail is further provided with a pick-and-place location for a user to pick up a first review slide;

the controller is used for controlling the second transfer mechanism to transfer a first review slide at a corresponding position in the sample image scanning device into the second accommodating structure positioned at the transfer position when receiving the review push-out instruction, and controlling the first transfer mechanism to move to the taking and placing position so as to enable a user to take out the first review slide through the taking and placing position.

6. A slide transfer device as claimed in claim 3 or claim 5 wherein the first or second receiving structure is further adapted to receive a second review slide, the controller being adapted to control movement of the first transfer mechanism along the first track to the pick-and-place position upon receipt of a review push-in instruction for a user to insert a second review slide into the first or second receiving structure via the pick-and-place position and to control movement of the first transfer mechanism to the index position and to control movement of the second transfer mechanism to the scan position of the second review slide in the index position.

7. A slide transfer device as claimed in claim 2 or claim 4 wherein the first receiving structure is for receiving a slide basket loaded with a first slide, the first track further being provided with a retrieval station, the controller further being adapted to control the first transfer mechanism to transfer an empty slide basket to the retrieval station when the second transfer mechanism removes all slides within the transferred slide basket.

8. The slide transfer device of claim 1, wherein the second slide comprises an emergency slide and/or a first review slide, the first receiving structure or the second receiving structure is further configured to receive a second review slide, and the first rail is further provided with a pick-and-place position for a user to place the emergency slide or place the second review slide or remove the first review slide;

the slide transfer device further includes:

the interaction module is at least used for being operated by a user to generate emergency instructions or compound instruction or compound push instructions, wherein the emergency instructions comprise emergency push instructions and emergency push instructions;

the controller is used for controlling the first transfer mechanism to move out of the transfer position to the taking and placing position when the emergency push-in instruction is received, controlling the first transfer mechanism to transfer the emergency slide to the transfer position when the emergency push-out instruction is received, controlling the second transfer mechanism to transfer the emergency slide from the transfer position to the scanning position, and/or controlling the second transfer mechanism to transfer the first review slide at the corresponding position in the sample image scanning device to the second containing structure at the transfer position when the review push-out instruction is received, and controlling the first transfer mechanism to transfer the first review slide from the transfer position to the taking and placing position; and/or the controller is used for controlling the first transfer mechanism to move out from the transfer position to the picking and placing position when receiving a re-diagnosis pushing-in command so as to enable a second re-diagnosis slide to be placed into the first accommodating structure or the second accommodating structure through the picking and placing position, and controlling the second transfer mechanism to transfer the second re-diagnosis slide to the scanning position.

9. A slide transfer device as claimed in claim 1, further comprising a sample introduction mechanism comprising a second rail connected to the first rail and a first pushing assembly for driving the slide basket loaded with a first slide along the second rail to push the slide basket to the first rail, wherein the second rail is disposed perpendicular to the first rail and/or the second rail is for stitching with a pusher for transferring the slide basket loaded with a first slide to the second rail; and/or the number of the groups of groups,

the first rail also has a recovery position, and the first transfer mechanism is also used for transferring the empty slide basket to the recovery position; the slide transferring device further comprises a sample discharging mechanism, the sample discharging mechanism comprises a third track and a second pushing assembly, the recovery position is in butt joint with the third track, the second pushing assembly is used for pushing the empty slide basket positioned at the recovery position to the third track, and the third track is perpendicular to the first track; or, the recycling position is used for being spliced with a recycling device so that the recycling device receives the empty slide basket, or is used for being spliced with a slice pushing machine, and the slice pushing machine is used for transferring prepared slides into the empty slide basket and sending the slide basket loaded with the slides into the sample image scanning device.

10. The slide transfer device of claim 1, wherein the second slide comprises an emergency slide and/or a first review slide, the second containment structure comprising:

at least one first accommodating groove, wherein the first accommodating groove is used for accommodating the emergency slide; and/or the number of the groups of groups,

the second accommodating groove is used for accommodating the first review slide.

11. A slide transfer device as claimed in claim 10 wherein the second receiving structure includes a first receiving slot and a second receiving slot, the first receiving slot and the second receiving slot being spaced apart to provide a predetermined distance for a user to take and place slides _。

12. The slide transfer device according to claim 11, wherein a picking and placing position is further provided on the first rail, the picking and placing position is used for a user to put in the emergency slide and/or pick and place the first review slide, the slide transfer device is provided with a cover shell covered on the first rail, a picking and placing opening corresponding to the picking and placing position is provided on the cover shell, and the second accommodating structure is provided with an opening for a second slide to be taken out;

the diameter of the pick-and-place opening is smaller than the distance between the first accommodating groove and the second accommodating groove, so that a user can take out or put in a piece of glass slide each time.

13. The slide transfer device of claim 11, wherein the first rail is further provided with a pick-and-place location for a user to place the emergency slide and/or pick-and-place the first review slide; the slide transfer device further includes:

and the controller is used for controlling the first transfer mechanism to move along the first track for a first distance so that the position of the first accommodating groove corresponds to the picking and placing position, and/or controlling the first transfer mechanism to move along the first track for a second distance so that the position of the second accommodating groove corresponds to the picking and placing position.

14. A slide transfer device as claimed in claim 1, wherein the first receiving structure is for receiving a slide basket loaded with a first slide, the first receiving structure including a first pushing portion and a second pushing portion, the first pushing portion being spaced apart from the second pushing portion along an extension of the first track, the first pushing portion and the second pushing portion enclosing to form a first receiving position for receiving the slide basket, the first pushing portion being for pushing the slide basket when the first transfer mechanism is moved to the neutral position, the second pushing portion being for pushing the slide basket when the first transfer mechanism is moved out of the neutral position; and/or the number of the groups of groups,

the first transfer mechanism further comprises a first driving module, at least one of the first accommodating structure and the second accommodating structure is connected to the first driving module, and the first driving module is used for driving the first accommodating structure and the second accommodating structure to synchronously move along the first track; and/or the number of the groups of groups,

the slide has the vertical state when injecting the sample and the horizontal state when scanning, and second transfer mechanism includes first transfer subassembly and second transfer subassembly, first transfer subassembly is used for shifting vertical state's slide, with be located the slide of the vertical state of transfer to the second transfer subassembly, the second transfer subassembly has the buffer memory seat, the buffer memory seat is equipped with the buffer memory position that is used for placing the slide, the buffer memory seat can overturn, so that be located the slide of buffer memory position switches between vertical state and horizontal state, the second transfer subassembly still is used for the slide of transfer horizontal state between buffer memory position and the scanning position.

15. A sample image scanning apparatus comprising a slide transfer device as claimed in any one of claims 1 to 14.