CN116077405A

CN116077405A - Anti-hair-loss and anti-dandruff shampoo containing saccharomyces cerevisiae protein hydrolysate and preparation process thereof

Info

Publication number: CN116077405A
Application number: CN202211335082.6A
Authority: CN
Inventors: 林学镁; 赵文忠; 李娜; 李洪波; 纪晓虹; 林琪
Original assignee: Lafang China Co ltd
Current assignee: Lafang China Co ltd
Priority date: 2022-10-28
Filing date: 2022-10-28
Publication date: 2023-05-09

Abstract

The invention discloses an anti-desquamation shampoo containing saccharomyces cerevisiae protein hydrolysate, which is prepared from five phases of A, B, C, D and E, wherein the phase A at least comprises water and a cleaning component, the phase B at least comprises a desquamation component, the phase C at least comprises an antipruritic component, the phase D at least comprises a plant extract, and the phase E at least comprises a protein component. The invention adopts the synergistic effect of the myristamide propyl PG-dimethyl ammonium chloride phosphate and the piroctone olamine salt, can effectively inhibit malassezia and improve the antibacterial rate, thereby effectively radically treating dandruff and relieving itching, is different from the traditional product which temporarily eliminates dandruff in a degreasing way, and has long-acting property in removing dandruff. And the shampoo can produce better oil control and moisture preservation effects, reduce the irritation of salicylic acid to skin mucous membrane and eye mucous membrane, improve the alopecia effect of the shampoo, reduce the problem of hair loss in the shampoo process, and increase the hair density.

Description

Anti-hair-loss and anti-dandruff shampoo containing saccharomyces cerevisiae protein hydrolysate and preparation process thereof

Technical Field

The invention relates to an anti-hair-loss and anti-dandruff shampoo containing saccharomyces cerevisiae protein hydrolysate and a preparation process thereof, and relates to A61K, in particular to the field of dressing and making-up configuration products.

Background

With the development of society, the life pressure of people is increased, the alopecia phenomenon is more and more common, and most of alopecia problems caused by the imbalance of hormone secretion due to the large pressure are more and more common. In addition to stress alopecia, improper use of shampoo further results in exacerbation of the problem of hair loss, which is accompanied by hair loss, and dandruff and itching problems afflict a large portion of the population. Most of the anti-dandruff shampoos on the market at present temporarily eliminate dandruff from the appearance by degreasing, serious dandruff trouble occurs again once the shampoo is stopped, and scalp sensitivity and skin barrier damage can be caused by long-term use of the anti-dandruff shampoo by degreasing. Therefore, it is important to develop a shampoo with the effects of removing dandruff and relieving itching and preventing alopecia.

The Chinese patent CN202210798060.7 discloses a plant shampoo capable of preventing hair loss, strengthening hair, removing dandruff and relieving itching and a preparation method thereof, wherein the plant shampoo prepared by introducing plant combination extract, cocamidopropyl PG-dimethyl ammonium chloride phosphate and piroctone olamine synergistic effect is safe and mild, has the effects of preventing hair loss, strengthening hair, removing dandruff and relieving itching, but only can achieve short-term anti-dandruff effect, and cannot achieve long-term anti-dandruff effect. Chinese patent No. 201710952333.8 discloses a Chinese medicinal shampoo powder for removing dandruff, relieving itching and preventing alopecia and a preparation method thereof, wherein various Chinese medicinal plants are ground into powder, and the effects of dispelling wind, activating blood, dredging channels and collaterals, nourishing blood, moistening hair, resisting allergy, sterilizing and decontaminating are achieved according to the matching of the Chinese medicinal herbs, but the prepared shampoo powder is inconvenient to use, and a user is required to prepare a solution for use, so that the steps are complicated.

Disclosure of Invention

In order to improve the anti-dandruff and antipruritic effects of the shampoo and maintain the long-term sterilizing and anti-dandruff effects, the first aspect of the invention provides an anti-dandruff shampoo containing saccharomyces cerevisiae protein hydrolysate, which is prepared from five phases of A, B, C, D and E, wherein the phase A at least comprises water and cleaning components, the phase B at least comprises anti-dandruff components, the phase C at least comprises antipruritic components, the phase D at least comprises plant extracts, and the phase E at least comprises protein components; the total mass of the water-supplementing shampoo reaches 100 percent.

As a preferred embodiment, the phase A further comprises 0.1-1% of conditioning agent, 5-60% of cleaning component, 0.1-1% of humectant, 0.1-2% of thickener, 0.1-2% of emulsifier, 0.05-0.3% of pH regulator and 0.05-0.5% of softener by weight percentage.

As a preferred embodiment, the cleaning component is selected from one or a combination of several of anionic surfactants, cationic surfactants, nonionic surfactants, zwitterionic surfactants.

As a preferred embodiment, the zwitterionic surfactant is selected from one of an amino acid amphoteric surfactant or a betaine amphoteric surfactant, the substituents in the zwitterionic surfactant comprising cocoamide substituents.

As a preferred embodiment, the cleansing component is selected from one or a combination of several of sodium lauryl sulfate, sodium dodecylbenzene sulfonate, sodium laureth sulfate, sodium alpha-alkenyl sulfonate, imidazoline betaine, coco diethanolamide, coco amidopropyl betaine, dodecyl dimethyl amine oxide, alkyl glucoside, sodium methyl cocoyl taurate.

As a preferred embodiment, the cleansing component is a combination of anionic, nonionic and zwitterionic surfactants.

As a preferred embodiment, the weight ratio of anionic, nonionic and zwitterionic surfactants is (5-40): (0.5-5): (1-15).

As a preferred embodiment, the cleansing component is a combination of sodium laureth sulfate, cocamidopropyl betaine, alkyl glucoside, sodium methyl cocoyl taurate.

As a preferred embodiment, the weight ratio of sodium laureth sulfate, alkyl glucoside, cocamidopropyl betaine, sodium methyl cocoyl taurate is (5-40): (0.5-5): (1-10): (0.5-3).

The applicant finds that the shampoo has good cleaning effect by adopting the synergistic effect of anionic, nonionic and zwitterionic surfactants in the experimental process, and the shampoo forms fine and stable foam in the cleaning process and is easy to wash. The reason is that the anionic, nonionic and zwitterionic surfactants synergistically enhance the cleaning strength of the surfactants, and foam formed during use is dense and can quickly wet hair and combine with the grease on the hair surface, and the grease on the hair surface is taken away after cleaning, so that a good cleaning effect is achieved. The applicant has further found that anionic, nonionic and zwitterionic surfactants are employed with (5-40): (0.5-5): the weight ratio of (1-15) can make shampoo have good storage stability, and make folium Platycladi extract, radix Sophorae Flavescentis extract and hydrolyzed yeast protein uniformly dispersed in solvent to form stable emulsion system.

As a preferred embodiment, the thickener is selected from one or a combination of several of sodium chloride, ammonium chloride, carbomer, xanthan gum and acrylic acid ester copolymer.

As a preferred embodiment, the conditioning agent is selected from one or a combination of several of polydimethylsiloxane, polyquaternium-7, polyquaternium-39, guar hydroxypropyl trimethylammonium chloride and polyquaternium-10.

As a preferred embodiment, the conditioning agent is a combination of guar hydroxypropyl trimethylammonium chloride and polyquaternium-10.

As a preferred embodiment, the weight ratio of guar hydroxypropyl trimethyl ammonium chloride to polyquaternium-10 is (0.05-0.5): (0.05-0.5).

As a preferred embodiment, the humectant is PEG-7 glycerol cocoate. The thickener is cocoamidomethyl MEA. The emulsifier is myristamide propyl PG-dimethyl ammonium chloride phosphate. The pH regulator is citric acid. The softener is stearamidopropyl dimethylamine.

As a preferred embodiment, the phase B comprises, in weight percent, 0.1 to 0.5% of stabilizer I, 0.1 to 2% of antidandruff ingredient, 0.1 to 1% of panthenol and 0.5 to 1% of zinc salt.

As a preferred embodiment, the anti-dandruff component is piroctone olamine salt and salicylic acid.

As a preferred embodiment, the weight ratio of piroctone olamine salt to salicylic acid is (0.1-1): (0.05-1).

The applicant finds in the experimental process that the synergistic effect of the myristamide propyl PG-dimethyl ammonium chloride phosphate and piroctone olamine can obviously improve the anti-dandruff and antipruritic effects of the shampoo, and realize long-acting anti-dandruff and antipruritic effects. The possible reasons for the guess are: the solubility of the piroctone olamine in water is poor, the adding amount of the piroctone olamine in the shampoo using water as a solvent is not easy to be excessive, the anti-dandruff effect is poor, the solubility of the piroctone olamine in the water solvent can be increased by adopting the synergistic effect of the myristamide propyl PG-dimethyl ammonium chloride phosphate and the piroctone olamine, the adding amount of the piroctone olamine is increased, and the deposition amount of the piroctone olamine in a shampoo system is increased, so that the proliferation of malassezia is inhibited, the antibacterial rate of the shampoo is improved, the anti-dandruff effect is enhanced, the external channel generated by dandruff is fundamentally blocked, and the dandruff and the itching are radically cured.

As a preferred embodiment, the zinc salt is a combination of zinc PCA and zinc gluconate.

As a preferred embodiment, the weight ratio of zinc PCA to zinc gluconate is (0.05-0.5): (0.005-0.5).

The applicant finds that the grease excessively secreted on the surface of the scalp can be cleaned by introducing salicylic acid into the shampoo in the experimental process, and the shampoo has good oil control effect, but the excessive removal of the horny layer can be caused by using the salicylic acid for a long time, so that the defending capability of the scalp is reduced, and the stabbing pain or allergy problem is caused. The applicant can reduce the irritation of shampoo to scalp skin mucosa by introducing salicylic acid, betaine salicylate and PCA zinc in a synergistic way, and the skin mucosa is not too much irritated after careless eyes are not carelessly taken, and the possible reasons are hypothesized to be: the introduction of betaine salicylate can neutralize partial acidity of salicylic acid, reduce acid irritation of salicylic acid, and the existence of PCA zinc can combine with moisture, so that scalp stratum corneum can be kept in a moist state, the health of a barrier is maintained, and the irritation of salicylic acid to skin is further reduced. The applicant further found that the introduction of PCA zinc can also inhibit the activity of 5α -reductase and inhibit the conversion of male hormone, thereby reducing sebum secretion and realizing the oil control antibacterial effect.

As a preferred embodiment, the C phase comprises 0.1-1% by weight of antipruritic component and 0.01-0.5% by weight of amino acid.

As a preferred embodiment, the antipruritic component is betaine salicylate and the amino acid is arginine.

As a preferred embodiment, the D phase comprises 0.3-0.8% of stabilizer II, 0.00005-0.2% of vitamin, 0.1-1% of consistency regulator, 0.5-1% of essence and 0.2-3% of plant extract by weight percentage.

As a preferred embodiment, the stabilizer I is sodium benzoate and the stabilizer II is phenoxyethanol. The vitamin is vitamin H, commonly known as biotin. The consistency regulator is sodium chloride.

As a preferred embodiment, the plant extract is selected from one or more of biota orientalis extract, kuh-seng extract, ginger root extract, angelica extract, polygonum multiflorum extract and soapberry extract.

As a preferred embodiment, the plant extract is a combination of a biota orientalis (l.) leaf extract and a sophoraflavavescens (sophorae flavescens) extract.

As a preferred embodiment, the weight ratio of the biota orientalis extract to the kuh-seng extract is (0.1-2): (0.1-1).

As a preferred embodiment, the E phase comprises 0.0001-0.5% by weight of a protein component, which is a hydrolyzed protein component.

As a preferred embodiment, the protein component is a hydrolyzed yeast protein, is a protein hydrolysate of yeast for brewing fermentation, and consists of 16 amino acids.

The second aspect of the invention provides a preparation process of the anti-hair-loss and anti-dandruff shampoo containing saccharomyces cerevisiae protein hydrolysate, which comprises the following steps:

(1) Adding the phase A component into a stirring pot, stirring and heating to 80-90 ℃, and keeping for 20-40min until the phase A substance is completely dissolved;

(2) Cooling to 55-65deg.C, adding phase B, stirring and mixing;

(3) Cooling to 50-60deg.C, adding phase C, stirring and mixing;

(4) Cooling to 40-50deg.C, adding phase D, stirring and mixing;

(5) Cooling to 35-45deg.C, adding phase E, stirring and mixing;

(6) Cooling to 35-40deg.C, controlling pH to 5-6, and discharging.

As a preferred embodiment, step 6 controls the pH to 5.2-5.7.

Compared with the prior art, the invention has the following beneficial effects:

(1) According to the anti-dandruff shampoo, the synergistic effect of the myristamide propyl PG-dimethyl ammonium chloride phosphate and the piroctone olamine salt is adopted, so that malassezia can be effectively inhibited, the antibacterial rate is improved, dandruff is effectively and radically treated, the scalp itch is relieved, the anti-dandruff shampoo is different from the traditional product, and the anti-dandruff shampoo has long-acting effect by temporarily eliminating the dandruff through a degreasing mode.

(2) The anti-hair loss and anti-dandruff shampoo adopts the synergistic effect of salicylic acid, betaine salicylate and PCA zinc, and adopts (0.05-1): (0.1-1): (0.05-0.5) can produce better oil control and moisture preservation effects, and reduce the irritation of salicylic acid to skin mucous membrane and eye mucous membrane.

(3) The anti-hair loss and anti-dandruff shampoo disclosed by the invention adopts the combination of anionic, nonionic and amphoteric ion surfactants as the cleaning component, so that the shampoo can generate fine, stable and rich foam, the cleaning effect is excellent, the prepared shampoo has good stability, is not easy to delaminate in a high-low temperature environment under the centrifugation condition, and can be stored for a long time.

(4) According to the anti-hair loss and anti-dandruff shampoo, the cacumen biotae extract, the radix sophorae flavescentis extract and the hydrolyzed yeast protein are introduced into the phase D and the phase E, wherein the hydrolyzed yeast protein acts on seven target proteins (keratin 71, mao Touming protein, keratin 14, keratin 17, collagen IV and collagen I, CD) for culturing hair follicles, so that hair follicle tissues are comprehensively protected, the anti-hair loss effect of the shampoo is synergistically improved, the hair loss problem in the hair washing process is reduced, and the hair density is increased.

(5) The anti-hair loss and anti-dandruff shampoo has a good oil control effect, can fully relieve scalp inflammation and shape hair health, and has remarkable effect especially for young men with vigorous grease secretion.

Drawings

FIGS. 1-3 are test charts of three parallel test inhibition zones of example 1.

Detailed Description

Example 1

An anti-desquamation shampoo containing Saccharomyces cerevisiae protein hydrolysate is prepared from five phases of A, B, C, D and E.

The weight percentage is as follows: the phase A also comprises 0.5% of conditioner, 40% of cleaning component, 0.5% of humectant, 1% of thickener, 1.2% of emulsifier, 0.15% of pH regulator, 0.26% of softener and 100% of water supplementing shampoo.

The conditioning agent is a combination of guar hydroxypropyl trimethyl ammonium chloride and polyquaternium-10, and the weight ratio is 0.1:0.25, said polyquaternium-10 is purchased from Shanghai source leaf biotechnology Co., ltd., CAS number: 68610-92-4. The cleaning component is a combination of sodium laureth sulfate, cocamidopropyl betaine, decyl glucoside and sodium methyl cocoyl taurate, and the weight ratio is 30:2.5:5:1.5.

the humectant is PEG-7 glycerol cocoate. The thickener is cocoamidomethyl MEA. The emulsifier is myristamide propyl PG-dimethyl ammonium chloride phosphate. The pH regulator is citric acid. The softener is stearamidopropyl dimethylamine.

The phase B comprises 0.1% of stabilizer I, 1.5% of anti-dandruff component, 0.5% of panthenol and 0.75% of zinc salt.

The anti-dandruff component comprises piroctone olamine salt and salicylic acid, and the weight ratio is 0.5:0.55.

the zinc salt is a combination of PCA zinc and zinc gluconate, and the weight ratio is 0.25:0.1.

the C phase comprises 0.5% of antipruritic component and 0.03% of amino acid.

The itching relieving component is betaine salicylate, and the amino acid is arginine.

The phase D comprises 0.3% of stabilizer II, 0.1% of vitamin, 0.1% of consistency regulator, 0.5% of essence and 1.5% of plant extract.

The stabilizer I is sodium benzoate, and the stabilizer II is phenoxyethanol. The vitamin is biotin. The consistency regulator is sodium chloride.

The plant extract is a combination of a biota orientalis leaf extract and a kuh-seng extract, and the weight ratio is 1.2:0.5.

the E phase comprises 0.25% of protein component, and the protein component is hydrolyzed yeast protein.

A preparation process of anti-hair-loss and anti-dandruff shampoo comprises the following steps:

(1) Adding the phase A component into a stirring pot, stirring and heating to 85 ℃, and keeping for 30min until all the phase A substances are dissolved;

(2) Cooling the stirring pot to 60 ℃, adding the phase B, stirring and mixing;

(3) Cooling the stirring pot to 55 ℃, adding the phase C, stirring and mixing;

(4) Cooling the stirring pot to 45 ℃, adding the phase D, and stirring and mixing;

(5) Cooling the stirring pot to 40 ℃, adding the phase E, and stirring and mixing;

(6) Cooling to 38deg.C, controlling pH to 5.5, and discharging.

Example 2

An anti-dandruff shampoo containing Saccharomyces cerevisiae protein hydrolysate and a preparation process thereof are provided, and the specific steps are the same as in example 1, except that the emulsifier is cocamidopropyl PG-dimethyl ammonium chloride phosphate, and the anti-dandruff component is piroctone olamine salt with mass fraction of 1%.

Example 3

An anti-dandruff shampoo containing Saccharomyces cerevisiae protein hydrolysate and a preparation process thereof are provided, and the specific steps are the same as those in the example 1, wherein the anti-dandruff shampoo comprises piroctone olamine salt and salicylic acid in a weight ratio of 0.5:1. the zinc salt is zinc gluconate.

Example 4

The specific steps of the anti-dandruff shampoo containing saccharomyces cerevisiae protein hydrolysate are the same as those of the embodiment 1, and the cleaning component is a combination of sodium laureth sulfate, cocamidopropyl betaine, dodecyl glucoside and sodium methyl cocoyl taurate, wherein the weight ratio is 26:3:8:2.

performance testing

1. Bacteriostasis test: the shampoo of example 1 was subjected to 3 parallel bacteriostasis performance tests according to the QW 66-inhibition zone test instruction, with A-I being 9 parallel samples. The larger the bacteriostatic diameter D (mm) is, the better the bacteriostatic effect is, and the better the anti-dandruff effect is predicted; the bacteriostasis area table is shown in table 1. The pictures of the bacteriostasis zone are shown in figures 1-3.

TABLE 1

The diameter measured by each antibacterial hole is larger than 7mm, and the antibacterial capacity is achieved. The mixed liquid of shampoo and water with mass concentration of 10% has effect of inhibiting malassezia.

2. Volunteer use feeling test: the volunteers living in the test population were matched with the shampoo prepared in example 1, and the number of finished questionnaires was 30. The use experience (fragrance, foam), product efficacy (anti-dandruff, oil control, antipruritic, supple), sensitivity (itchy head, pimple, dandruff, tight scalp, redness of scalp) were tested.

The use feeling test is shown in Table 2. The fragrance effect test is shown in Table 3. The foam effect test is shown in Table 4.

TABLE 2

The number of people	Anti-dandruff effect	Oil control effect	Antipruritic effect	Softening effect
					Satisfaction/person	16	16	20	9
General/person	14	13	10	21
					Dissatisfaction/person	0	1	0	0

TABLE 3 Table 3

	Very much like	Slightly like	In general	Is somewhat disfavored	Is very disfavored
						Fragrance effect-Human body	7	9	13	1	0

TABLE 4 Table 4

	Very much	Somewhat multiple	Moderate to moderate	Less and less	Very few
						Foam amount/person	5	6	18	1	0

3. And (3) testing the alopecia preventing effect: 10 healthy adults aged 18-60 years are selected, and the hair length is between 5cm and 40 cm: there are excessive hair loss and mild sparseness of hair. And the hair loss count is more than 10 according to the 60 times of hair combing method, the hair loss count is still more than 10 after the 2 weeks of washing-out period, and no special hair-dressing treatment is performed during nearly 1 month.

Local hair density: fixing a hair-cutting area of 1.5cm by 1.5cm on the head of the subject, positioning, and ensuring that the hair-cutting area is consistent when each visit is performed, wherein the residual length of hair is not more than 1mm: in the image acquisition process, an operator enables a subject to be in a comfortable position, the dermatoscope is placed at the center of a hair cutting area to carry out local hair image shooting, the dermatoscope lens is completely attached to the scalp and kept vertical during shooting, and the definition of a shot image is checked. Counting the number (root) and density (root/cm) of local hair by manual counting method ² ) And recorded.

The subjects were allowed to sit still in a laboratory at 21℃and 50% humidity for 30min before use, and after 4 weeks and 8 weeks of the shampoo of example 1, the subjects were allowed to sit still for 30min in a laboratory at 21℃and 50% humidity, and were allowed to perform a comb method for 60 times, and the number of hair loss was recorded. The test results are shown in Table 5.

TABLE 5

The comb method is carried out for 60 times: the subjects were unable to shampoo within 48#4 hours prior to each visit. The visiting day can not comb in the morning: each time after reaching the test facility to adapt to the environment. Comb of the same specification is adopted by the same trained technician, and the hair is uniformly combed for 60 times (30 times each) from left front to left back, right front to right back, and the hair is collected and counted.

The test results showed that after 4 and 8 weeks of use, the number of hair loss was reduced or changed little and the hair density was increased or changed little.

4. Stability test: the shampoo was left at-10 c for 3 months at 55 c, the apparent state of examples 1-4 was observed, and the appearance of delamination and floc problems were observed. The test results are shown in Table 6.

TABLE 6

	-10℃	55℃
			Example 1	No delamination and no flocculent turbidity	No delamination and no flocculent turbidity
Example 2	No delamination, floc appearance	No delamination and no flocculent turbidity
			Example 3	No delamination and no flocculent turbidity	No delamination and no flocculent turbidity
Example 4	No delamination and no flocculent turbidity	No delamination and no flocculent turbidity

Claims

1. An anti-desquamation shampoo containing saccharomyces cerevisiae protein hydrolysate is characterized in that the preparation raw materials comprise five phases of A, B, C, D and E, wherein the phase A at least comprises water and a cleaning component, the phase B at least comprises a desquamation component, the phase C at least comprises an antipruritic component, the phase D at least comprises a plant extract, and the phase E at least comprises a protein component; the total mass of the water-supplementing shampoo reaches 100 percent.

2. The anti-desquamation shampoo containing saccharomyces cerevisiae protein hydrolysate according to claim 1, wherein the phase a further comprises 0.1-1% of conditioning agent, 5-60% of cleaning component, 0.1-1% of humectant, 0.1-2% of thickening agent, 0.1-2% of emulsifying agent, 0.05-0.3% of pH regulator and 0.05-0.5% of softener by weight percentage.

3. The anti-desquamation shampoo containing saccharomyces cerevisiae protein hydrolysate according to claim 2, wherein the cleaning component is selected from one or a combination of several of anionic surfactant, cationic surfactant, nonionic surfactant and zwitterionic surfactant.

4. A hair-desquamation shampoo comprising a saccharomyces cerevisiae protein hydrolysate according to claim 3 wherein the zwitterionic surfactant is selected from one of an amino acid amphoteric surfactant or a betaine amphoteric surfactant, the substituents in the zwitterionic surfactant comprising cocoamide substituents.

5. The anti-desquamation shampoo containing saccharomyces cerevisiae protein hydrolysate according to claim 1, wherein the phase B comprises 0.1-0.5% of stabilizer i, 0.1-2% of desquamation component, 0.1-1% of panthenol and 0.5-1% of zinc salt by weight.

6. The anti-desquamation shampoo containing saccharomyces cerevisiae protein hydrolysate according to claim 1, wherein the C phase comprises 0.1-1% of antipruritic component and 0.01-0.5% of amino acid by weight percent.

7. The anti-desquamation shampoo containing saccharomyces cerevisiae protein hydrolysate according to claim 1, wherein the D phase comprises 0.3-0.8% of stabilizing agent II, 0.00005-0.2% of vitamin, 0.1-1% of consistency regulator, 0.5-1% of essence and 0.2-3% of plant extract by weight percentage.

8. The anti-dandruff shampoo comprising a saccharomyces cerevisiae protein hydrolysate according to claim 7, wherein the plant extract is selected from one or a combination of several of biota orientalis extract, kuh-seng extract, ginger root extract, angelica extract, polygonum multiflorum extract and soapberry extract.

9. The anti-desquamation shampoo containing saccharomyces cerevisiae protein hydrolysate according to claim 1, wherein the E phase comprises 0.0001-0.5% by weight of protein components, wherein the protein components are hydrolyzed protein components, preferably are protein hydrolysates of saccharomyces cerevisiae fermentation yeasts.

10. A process for preparing an anti-desquamation shampoo containing a saccharomyces cerevisiae protein hydrolysate according to any of the claims 1-9, characterized by the following steps:

(2) Cooling to 55-65deg.C, adding phase B, stirring and mixing;

(3) Cooling to 50-60deg.C, adding phase C, stirring and mixing;

(4) Cooling to 40-50deg.C, adding phase D, stirring and mixing;

(5) Cooling to 35-45deg.C, adding phase E, stirring and mixing;

(6) Cooling to 35-40deg.C, controlling pH to 5-6, and discharging.