CN116019631A - Clinical tool for noninvasive acute pancreatitis low-temperature treatment and use method thereof - Google Patents
Clinical tool for noninvasive acute pancreatitis low-temperature treatment and use method thereof Download PDFInfo
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- CN116019631A CN116019631A CN202310162218.6A CN202310162218A CN116019631A CN 116019631 A CN116019631 A CN 116019631A CN 202310162218 A CN202310162218 A CN 202310162218A CN 116019631 A CN116019631 A CN 116019631A
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Abstract
The invention relates to the technical field of medical equipment, in particular to a clinical tool for low-temperature treatment of noninvasive acute pancreatitis and a use method thereof. The invention can achieve the aim of treating acute pancreatitis by noninvasively, economically and rapidly inducing the local low temperature of pancreas, and adds a clinical tool for treating acute pancreatitis for clinicians.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to a clinical tool for low-temperature treatment of noninvasive acute pancreatitis and a use method thereof.
Background
Acute pancreatitis refers to acute abdomen that is caused by abnormal activation of pancreatin to digest the pancreas itself and surrounding organs and is characterized by local inflammatory reactions of the pancreas, which can even lead to organ dysfunction. Clinically, acute pancreatitis is characterized by acute upper abdominal pain, nausea, vomiting, fever, increased blood pancreatin, and the like. The pathological changes of acute pancreatitis are mild and severe, and the symptoms of acute pancreatitis mainly include pancreatic edema, which is clinically common. The pancreatic necrosis of a few severe patients is frequently caused by secondary infection, peritonitis, shock, multiple organ failure and the like, and the death rate is high. The annual incidence rate of acute pancreatitis is 13/10 ten thousand to 45/10 ten thousand, the incidence rate of acute pancreatitis in 20 years in China is increased from 0.19% to 0.71%,80% to 85% of patients are mild acute pancreatitis, the course of disease is self-limiting, the death rate is less than 1% -3%, but about 20% of patients can develop severe acute pancreatitis, and the death rate can reach 13% to 35%. Abnormal activation and secretion of pancreatin is a key factor in the development and progression of acute pancreatitis.
The metabolism of organisms is changed, and various special manifestations exist due to the catalysis of various enzymes, and a certain physicochemical rule is obeyed. The swedish physicist s.a. Arrhenius studied the effect of temperature on the chemical reaction rate, leading to a well-known Arrhenius relationship, where the metabolism of organisms and the catalytic reaction rate of enzymes decrease with decreasing temperature. It is known that external Zhou Jixing inflammation is effective in reducing inflammatory response by low temperature treatment. The low-temperature treatment can also effectively relieve inflammatory storm caused by acute pancreatitis, break the chain reaction of pancreatic inflammation and achieve the effect of effectively treating the acute pancreatitis.
However, systemic hypothermia can cause irreversible damage to the human body and even be life threatening. Because pancreas belongs to retroperitoneal organ, the position is deep, and the local temperature of pancreas needs to be reduced clinically, often needs to be placed in a tube through surgical means, and the purpose of reducing the local temperature of pancreas can be effectively achieved. Most pancreas is positioned on the back wall of stomach, the two are closely connected, the pancreas is cooled by cooling the stomach saccule, and meanwhile, the whole body low temperature is reduced to the greatest extent, no therapeutic tool capable of rapidly and effectively realizing noninvasive local reduction of pancreas temperature exists clinically at present, and therefore, a clinical tool for noninvasive acute pancreatitis low temperature therapy and a use method are needed to solve the problem.
Disclosure of Invention
The invention aims to provide a clinical tool for low-temperature treatment of noninvasive acute pancreatitis and a use method thereof, so as to solve the problems.
In order to achieve the above object, the present invention provides the following solutions:
the utility model provides a noninvasive acute pancreatitis cryotherapy clinical instrument, includes inflation cooling portion, inflation cooling portion middle part runs through and the rigid coupling has the gastric cavity pipe, gastric cavity pipe one end is equipped with drainage portion, drainage portion with be equipped with the distance between the inflation cooling portion, inflation cooling portion intercommunication has cold circulation portion, drainage portion is located keeping away from cold circulation portion's one end, gastric cavity pipe is hollow structure and link up both ends, be provided with guiding portion in the gastric cavity pipe.
Preferably, the expansion cooling part comprises a balloon, the gastric cavity tube penetrates through the middle of the balloon, two communicating pipes are communicated with the top of the balloon, one communicating pipe is far away from the liquid inlet end of the cold circulation part, and the other communicating pipe is far away from the liquid outlet end of the cold circulation part, wherein the liquid inlet end of the cold circulation part is communicated with one end of the communicating pipe.
Preferably, the volume of the inner cavity of the balloon is 250mL-500mL, the balloon is in a tension-free state, and the deformation range of the balloon after water injection is 1:1-1:1.5.
Preferably, the drainage part comprises a plurality of gastric cavity tube side holes, the gastric cavity tube side holes are positioned on the side wall of the end part of the gastric cavity tube, a distance is reserved between the gastric cavity tube side holes and the saccule, and a plurality of gastric cavity tube side holes are arranged in a matrix around the circumference of the gastric cavity tube.
Preferably, the gastric cavity tube and the two communicating tubes are arranged in parallel, the two communicating tubes are positioned on two sides of the gastric cavity tube, and the side wall of the gastric cavity tube is fixedly connected with the side wall of the communicating tube.
Preferably, the cold circulation part comprises a peristaltic pump and a cold water tank, wherein the liquid inlet end of the peristaltic pump is communicated with the liquid outlet end of the cold water tank, the liquid outlet end of the peristaltic pump is communicated with one of the communicating pipes, and the liquid inlet end of the cold water tank is communicated with the other communicating pipe.
Preferably, the communicating tube, the saccule and the gastric cavity tube are made of polyurethane.
Preferably, the guide part comprises a guide wire, the guide wire is sleeved in the gastric cavity tube, the end part of the guide wire is detachably connected with a cap, and the cap is detachably connected with one end of the gastric cavity tube, which is far away from the peristaltic pump. Preferably, the gastric lumen has an inner diameter of 3.5mm.
A use method of a clinical tool for noninvasive acute pancreatitis cryotherapy, which is based on the clinical tool for noninvasive acute pancreatitis cryotherapy and comprises the following steps:
s1, stretching the gastric cavity tube and the expansion cooling part into the esophagus of a patient through the nasal cavity by the guide part, enabling the expansion cooling part to enter the stomach of the patient along with the gastric cavity tube, and extracting gastric juice from the gastric cavity tube so as to ensure that the expansion cooling part smoothly enters the gastric cavity of the patient;
s2, injecting 250mL of physiological saline at 25 ℃ into the expansion cooling part, and expanding the expansion cooling part;
s3, after the expansion cooling part is placed successfully, communicating one end of the expansion cooling part outside the patient with the cold circulation part, and starting the cold circulation part to perform treatment;
and S4, maintaining the normal saline in the expansion cooling part at 25 ℃ by the cold circulation part for 2 hours, and completing one treatment course.
The invention has the following technical effects: besides the prior medicine and surgical method measures, the invention achieves the aim of treating the acute pancreatitis by noninvasively, economically and rapidly inducing the local low temperature of pancreas, and adds a clinical tool for treating the acute pancreatitis for clinicians.
Drawings
For a clearer description of an embodiment of the invention or of the solutions of the prior art, the drawings that are needed in the embodiment will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the invention, and that other drawings can be obtained according to these drawings without inventive effort for a person skilled in the art:
FIG. 1 is a schematic diagram of the structure of the present invention;
FIG. 2 is a schematic cross-sectional view of a gastric lumen and communication tube according to the present invention;
FIG. 3 is a schematic view of the device of the present invention in use during treatment;
FIG. 4 is a cross-sectional view of the structure of the present invention;
FIG. 5 is an enlarged view of a portion of FIG. 4A in accordance with the present invention;
wherein, 1, gastric cavity tube; 2. a communicating pipe; 3. a balloon; 4. a gastric lumen side hole; 5. a guide wire; 6. and (5) sleeving a cap.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
In order that the above-recited objects, features and advantages of the present invention will become more readily apparent, a more particular description of the invention will be rendered by reference to the appended drawings and appended detailed description.
Referring to fig. 1 to 3, the invention provides a clinical tool for low-temperature treatment of noninvasive acute pancreatitis, which comprises an expansion cooling part, wherein the middle part of the expansion cooling part is penetrated and fixedly connected with a gastric cavity tube 1, one end of the gastric cavity tube 1 is provided with a drainage part, a distance is arranged between the drainage part and the expansion cooling part, the expansion cooling part is communicated with a cold circulation part, the drainage part is positioned at one end far away from the cold circulation part, the gastric cavity tube 1 is in a hollow structure and penetrates through two ends, and a guide part is arranged in the gastric cavity tube 1.
When the device is used, the gastric cavity tube 1 and the expansion cooling part fixedly connected with the gastric cavity tube 1 are fed into the gastric cavity through the nose and the esophagus, one end of the gastric cavity tube 1 positioned outside the body can be communicated with a negative pressure bottle, when gastric cavity tube 1 sucks gastric juice in the gastric cavity, the expansion cooling part is indicated to be placed in place, then the expansion cooling part is expanded, one end of the expansion cooling part positioned outside the body is communicated with the cold circulation part, and the cold circulation part is started, so that the pancreatic partial low-temperature treatment can be started.
Further optimizing scheme, inflation cooling part includes sacculus 3, and sacculus 3 is run through to stomach lumen 1 middle part, and sacculus 3 top intercommunication has two communicating pipes 2, and one of them communicating pipe 2 is kept away from sacculus 3 one end intercommunication and is had the feed liquor end of cold circulation portion, and another communicating pipe 2 is kept away from sacculus 3 one end intercommunication and has the play liquid end of cold circulation portion.
The gastric lumen 1 extends through the middle of the balloon 3 without communicating with the balloon 3.
According to the further optimized scheme, the volume of the inner cavity of the balloon 3 is 250mL-500mL, the balloon 3 is in a tension-free state, and the deformation range of the balloon 3 after water injection is 1:1-1:1.5.
Before use, the balloon 3 is in a non-tension state, the balloon 3 is inflated and enlarged after water injection, the deformation range of the balloon 3 is 1-1.5 times of the initial volume, when the balloon 3 is placed in a gastric cavity and is communicated with an injector through any one of the communication pipes 2, 250mL of physiological saline at 25 ℃ is injected into the balloon 3 to inflate the balloon 3, so that the surface area of the balloon 3 in the gastric cavity is increased, the cooling area is increased, and the cooling effect is improved.
The liquid inlet end and the liquid outlet end of the cold circulation part are respectively communicated with the communicating pipe 2, the cold circulation part, the two communicating pipes 2 and the saccule 3 form a closed loop, so that the cooled physiological saline flows in the closed loop, and the physiological saline is maintained at 25 ℃ through the cold circulation part.
Further optimizing scheme, drainage portion includes a plurality of gastric cavity tube side openings 4, and gastric cavity tube side opening 4 is located gastric cavity tube 1 tip lateral wall, reserves the distance between gastric cavity tube side opening 4 and the sacculus 3, and a plurality of gastric cavity tube side openings 4 are the matrix setting around gastric cavity tube 1 circumference.
After the gastric cavity tube 1 is penetrated into the gastric cavity, a plurality of gastric cavity tube side holes 4 at the tail end of the gastric cavity tube 1 are immersed into gastric juice, the gastric juice can enter the gastric cavity tube 1 through the gastric cavity tube side holes 4 and is discharged outwards under the action of a negative pressure bottle communicated with the gastric cavity tube 1, and the discharge of the gastric juice can indicate that the saccule 3 reaches a designated position.
The arrangement of the gastric cavity tube side hole 4 plays a role in draining gastric juice and exhausting gastric cavity gas.
In a further optimized scheme, the gastric cavity tube 1 and the two communicating tubes 2 are arranged in parallel, the two communicating tubes 2 are positioned at two sides of the gastric cavity tube 1, and the side wall of the gastric cavity tube 1 is fixedly connected with the side wall of the communicating tube 2.
As shown in fig. 2, the gastric cavity tube 1 and the two communicating tubes 2 are arranged in parallel, the two communicating tubes 2 are positioned at two sides of the top of the gastric cavity tube 1 and are symmetrically arranged, and the gastric cavity tube 1 and the two communicating tubes 2 are arranged in parallel to form a pipeline, so that the whole gastric cavity tube is convenient to enter the patient.
Wherein, the distance A is 0.7mm, the distance B is 3.5mm, the distance C is 0.5mm, and the distance D is 5.7mm.
Further optimizing scheme, cold circulation portion includes peristaltic pump and cold water tank, and the feed liquor end of peristaltic pump communicates with the play liquid end of cold water tank, and the play liquid end of peristaltic pump communicates with one of them communicating pipe 2, and the feed liquor end of cold water tank communicates with another communicating pipe 2.
As shown in fig. 3, the peristaltic pump, the cold water tank, the communicating tube 2 and the balloon 3 are a closed loop, and after the physiological saline is injected into the balloon 3, the physiological saline circulating in the communicating tube 2 is kept at 25 ℃ through the cold water tank, the flow rate of the physiological saline is controlled through the peristaltic pump, and the physiological saline circulating in the communicating tube 2 and the balloon 3 is driven to flow.
In a further optimized scheme, the communicating pipe 2, the saccule 3 and the gastric cavity tube 1 are made of polyurethane.
Further optimizing scheme, the guide part includes seal wire 5, and seal wire 5 cover is established in gastric cavity pipe 1, and seal wire 5's tip can be dismantled and be connected with cover cap 6, and cover cap 6 is connected with gastric cavity pipe 1 one end of keeping away from the peristaltic pump can be dismantled.
The seal wire 5 sets up in gastric cavity 1, the setting of seal wire 5 is convenient for carry communicating pipe 2 and sacculus 3 with gastric cavity 1 and enters into the patient in to the tip of seal wire 5 can be dismantled and be connected with cover cap 6, and the end at seal wire 5 is established to cover cap 6 cover, and the one end extrusion of cover cap 6 is installed in gastric cavity 1's cavity afterwards, and the external diameter of cover cap 6 is greater than gastric cavity 1's cavity diameter, makes cover cap 6 only one side tip enter into gastric cavity 1, after sacculus 3 is placed, pulls hard seal wire 5, and cover cap 6 makes the tip of seal wire 5 separate with the one end of cover cap 6 under the hindrance of gastric cavity 1.
The guide wire 5 and the cap 6 are provided for facilitating the patient to take down the tube, which is the prior art and will not be described in detail here.
Further optimizing scheme, the internal diameter of gastric cavity pipe 1 is 3.5mm.
A use method of a clinical tool for noninvasive acute pancreatitis cryotherapy, which is based on the clinical tool for noninvasive acute pancreatitis cryotherapy and comprises the following steps:
s1, stretching a gastric cavity tube 1 and an expansion cooling part into the esophagus of a patient through a nasal cavity by a guide part, and allowing the expansion cooling part to enter the stomach of the patient along with the gastric cavity tube 1, and extracting gastric juice from the gastric cavity tube 1 so as to ensure that the expansion cooling part smoothly enters the gastric cavity of the patient;
when in use, the gastric cavity tube 1, the communicating tube 2 and the saccule 3 extend into the esophagus of a patient through the nasal cavity through the lead and enter the stomach of the patient, one end of the gastric cavity tube 1 outside the patient is communicated with a negative pressure bottle, and under the action of the negative pressure bottle, gastric juice in the gastric cavity enters the gastric cavity tube 1 through the gastric cavity tube side hole 4 and is sucked into the negative pressure bottle so as to ensure that the saccule 3 is positioned in the gastric cavity.
S2, injecting 250mL of physiological saline at 25 ℃ into the expansion cooling part, and expanding the expansion cooling part;
the balloon 3 was inflated by injecting 250mL of physiological saline at 25℃into the balloon 3 through the communication tube 2.
S3, after the expansion cooling part is placed successfully, communicating one end of the expansion cooling part outside the patient with the cold circulation part, and starting the cold circulation part to perform treatment;
then, the end part of any communicating pipe 2 is communicated with the water outlet of the peristaltic pump, the other communicating pipe 2 is communicated with the water inlet of the cold water tank to form a closed loop, the peristaltic pump is started, and the physiological saline flows in the formed closed loop under the action of the peristaltic pump. The cold water tank maintains the physiological saline at 25 ℃.
S4, maintaining the normal saline in the expansion cooling part at 25 ℃ by the cold circulation part for 2 hours, and completing one treatment course.
The cold water tank maintains the physiological saline at 25 ℃. The physiological saline circularly flows for 2 hours to finish the treatment of one course of treatment.
In the description of the present invention, it should be understood that the terms "longitudinal," "transverse," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like indicate or are based on the orientation or positional relationship shown in the drawings, merely to facilitate description of the present invention, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the present invention.
The above embodiments are only illustrative of the preferred embodiments of the present invention and are not intended to limit the scope of the present invention, and various modifications and improvements made by those skilled in the art to the technical solutions of the present invention should fall within the protection scope defined by the claims of the present invention without departing from the design spirit of the present invention.
Claims (10)
1. A clinical tool for the low-temperature treatment of noninvasive acute pancreatitis, which is characterized in that: including inflation cooling portion, inflation cooling portion middle part runs through and the rigid coupling has gastric cavity pipe (1), gastric cavity pipe (1) one end is equipped with drainage portion, drainage portion with be equipped with the distance between the inflation cooling portion, inflation cooling portion intercommunication has cold circulation 2 ring portion, drainage portion is located keeping away from the one end of cold circulation portion, gastric cavity pipe (1) are hollow structure and link up both ends, be provided with guiding portion in gastric cavity pipe (1).
2. A clinical tool for the cryotreatment of non-invasive acute pancreatitis according to claim 1, wherein: the inflatable cooling part comprises a balloon (3), the gastric cavity tube (1) penetrates through the middle of the balloon (3), two communicating pipes (2) are communicated with the top of the balloon (3), one communicating pipe (2) is far away from a liquid inlet end of the balloon (3) with a cold circulation part communicated with one end, and the other communicating pipe (2) is far away from a liquid outlet end of the balloon (3) with the cold circulation part communicated with one end.
3. A clinical tool for the cryotreatment of non-invasive acute pancreatitis according to claim 2, characterized in that: the inner cavity of the balloon (3) has a volume of 250-500 mL, the balloon (3) is in a tension-free state, and the deformation range of the balloon (3) after water injection is 1:1-1:1.5.
4. A clinical tool for the cryotreatment of non-invasive acute pancreatitis according to claim 2, characterized in that: the drainage part comprises a plurality of gastric cavity tube side holes (4), the gastric cavity tube side holes (4) are positioned on the side wall of the end part of the gastric cavity tube (1), a distance is reserved between the gastric cavity tube side holes (4) and the sacculus (3), and a plurality of gastric cavity tube side holes (4) are arranged around the circumference of the gastric cavity tube (1) in a matrix mode.
5. A clinical tool for the cryotreatment of non-invasive acute pancreatitis according to claim 2, characterized in that: the gastric cavity tube (1) and the two communicating tubes (2) are arranged in parallel, the two communicating tubes (2) are positioned on two sides of the gastric cavity tube (1), and the side wall of the gastric cavity tube (1) is fixedly connected with the side wall of the communicating tube (2).
6. A clinical tool for the cryotreatment of non-invasive acute pancreatitis according to claim 2, characterized in that: the cold circulation part comprises a peristaltic pump and a cold water tank, wherein the liquid inlet end of the peristaltic pump is communicated with the liquid outlet end of the cold water tank, the liquid outlet end of the peristaltic pump is communicated with one communicating pipe (2), and the liquid inlet end of the cold water tank is communicated with the other communicating pipe (2).
7. A clinical tool for the cryotreatment of non-invasive acute pancreatitis according to claim 2, characterized in that: the communicating pipe (2), the saccule (3) and the gastric cavity tube (1) are made of polyurethane materials.
8. A clinical tool for the cryotreatment of non-invasive acute pancreatitis according to claim 6, wherein: the guide part comprises a guide wire (5), the guide wire (5) is sleeved in the gastric cavity tube (1), a cap (6) is detachably connected to the end part of the guide wire (5), and the cap (6) is detachably connected with one end of the gastric cavity tube (1) away from the peristaltic pump.
9. A clinical tool for the cryotreatment of non-invasive acute pancreatitis according to claim 1, wherein: the inner diameter of the gastric cavity tube (1) is 3.5mm.
10. A method of using a non-invasive acute pancreatitis cryogenically therapeutic clinical tool, based on any one of claims 1-9, comprising the steps of:
s1, stretching the gastric cavity tube (1) and the expansion cooling part into the esophagus of a patient through the guide part, wherein the expansion cooling part enters the stomach of the patient along with the gastric cavity tube (1), and gastric juice is extracted from the gastric cavity tube (1) so as to ensure that the expansion cooling part smoothly enters the gastric cavity of the patient;
s2, injecting 250mL of physiological saline at 25 ℃ into the expansion cooling part, and expanding the expansion cooling part;
s3, after the expansion cooling part is placed successfully, communicating one end of the expansion cooling part outside the patient with the cold circulation part, and starting the cold circulation part to perform treatment;
and S4, maintaining the normal saline in the expansion cooling part at 25 ℃ by the cold circulation part for 2 hours, and completing one treatment course.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310162218.6A CN116019631A (en) | 2023-02-22 | 2023-02-22 | Clinical tool for noninvasive acute pancreatitis low-temperature treatment and use method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310162218.6A CN116019631A (en) | 2023-02-22 | 2023-02-22 | Clinical tool for noninvasive acute pancreatitis low-temperature treatment and use method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN116019631A true CN116019631A (en) | 2023-04-28 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310162218.6A Pending CN116019631A (en) | 2023-02-22 | 2023-02-22 | Clinical tool for noninvasive acute pancreatitis low-temperature treatment and use method thereof |
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| CN (1) | CN116019631A (en) |
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- 2023-02-22 CN CN202310162218.6A patent/CN116019631A/en active Pending
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