CN115813843A

CN115813843A - Mite-clearing, acne-relieving, anti-inflammation, sterilization, restoration and nourishing gel and preparation method thereof

Info

Publication number: CN115813843A
Application number: CN202211628402.7A
Authority: CN
Inventors: 孙淑萍; 李田; 吴俐; 李胜利; 李博林; 代雨晗; 李安琪; 刘侠; 裴中旭; 王梁; 孙琪; 檀圆圆; 谢先进; 朱恩泽; 韩雪; 杜云艳; 姚清晨
Original assignee: Wannan Medical College
Current assignee: Wannan Medical College
Priority date: 2022-12-17
Filing date: 2022-12-17
Publication date: 2023-03-21

Abstract

The invention discloses a mite-clearing acne-relieving anti-inflammation sterilization repair nourishing gel and a preparation method thereof, and the gel comprises the following components: the main raw materials of the traditional Chinese medicine composition comprise Adinandra, eucalyptus oil, evening primrose oil, peppermint oil, blumea oil, perilla seed oil, green zanthoxylum seed soaking oil, lithospermum soaking oil, seabuckthorn fruit oil, biological polysaccharide gum, white vinegar, white peony root extracting solution, scutellaria baicalensis extracting solution, rhodiola rosea extracting solution, frankincense extracting solution, propolis extracting solution, garlic extracting solution, mangnolia officinalis extracting solution, an ice crystal forming agent AVC, a U30 cellulose thickening agent, sodium alginate, distilled water, 1, 2-propylene glycol and ethylparaben. Compared with the prior art, the mite-clearing, acne-relieving, anti-inflammation, sterilization, restoration and nourishing gel provided by the invention contains various natural plant active ingredients, is fine and uniform in texture, proper in viscosity, good in spreadability, fragrant in smell, safe and mild, can relieve acne while removing mites and sterilizing for a long time, deeply permeates skin, enables the skin to revive vitality and helps the skin to recover to a healthy state.

Description

Mite-clearing, acne-relieving, anti-inflammation, sterilization, restoration and nourishing gel and preparation method thereof

Technical Field

The invention belongs to the field of cosmetics, and particularly relates to a mite-clearing, acne-relieving, anti-inflammation, sterilization, restoration and nourishing gel and a preparation method thereof.

Background

Most people have mites on their faces, and the breeding and growth of mites require the absorption of nutrients from the skin, and if the number of mites exceeds a normal range, skin diseases are easily induced. Meanwhile, the mite secretion can cause pore blockage, so that the skin becomes rough, and the cutin becomes thicker gradually, which is also one of important factors for inducing the formation of the acne.

Acne is a chronic inflammatory skin disease in pilosebaceous glands, and is caused by blockage of sebaceous gland ducts and pores due to various factors, so that sebum outflow is not smooth. Clinically, it is manifested as facial skin lesions with multiple forms such as acne, pimple, pustule, and nodule. Acne is formed from a variety of causes, most notably by the release of sebum-solubilizing lipases by parasites such as Propionibacterium acnes, which convert sebum into free fatty acids. These acidic products cause inflammation of the hair follicles and their surroundings, causing acne.

Acne mainly occurs to teenagers, and if the acne is not removed in time, skin inflammation can be caused, facial beauty can be affected, so that the psychological and social effects of the teenagers are greatly affected, and negative emotions such as appearance anxiety and the like are easily induced.

In view of this phenomenon, many products for relieving acne appear on the market, but most of these products are composed of irritant chemical substances, and if such components are added too much, allergic dermatitis can be caused, and the horny layer is weakened, so that the skin becomes rough and dull, and even hair follicles and sebaceous gland openings are stimulated, and further keratinization is proliferated, so that vicious circle is caused, and acne is difficult to improve.

Disclosure of Invention

The invention aims to provide an anti-inflammation, sterilization, restoration and nourishing gel for removing mites, relieving acne and a preparation method thereof, which contains various natural plant essential oils and plant extract components, has mild properties, can remove mites, sterilize, resist inflammation, restore skin, relieve acne, deeply permeate, mildly nourish skin, restore and nourish skin, revive skin and have wide market prospect.

The specific technical scheme of the invention is as follows:

the mite-clearing, acne-relieving, anti-inflammation, sterilization, restoration and nourishing gel comprises the following raw materials in parts by weight:

the green zanthoxylum seed soaking oil is prepared by the following method:

weighing a proper amount of green pepper seed coarse powder, adding seabuckthorn fruit oil which is 3-5 times the weight of the green pepper seed coarse powder, soaking for 3-6 days, performing ultrasonic extraction with the ultrasonic power of 200-600W, heating to 30-60 ℃, performing ultrasonic extraction for 0.5-3.0h, filtering, and taking filtrate to obtain green pepper seed soaking oil for later use;

the lithospermum soaking oil is prepared by the following steps:

weighing a proper amount of gromwell coarse powder, adding tea seed oil with the weight of 8-10 times of the gromwell coarse powder, hermetically soaking for 5-7 days, performing ultrasonic extraction with the ultrasonic power of 200-600W, heating to 30-60 ℃, performing ultrasonic extraction for 0.5-3.0h, filtering, and taking filtrate to obtain gromwell soaking oil for later use.

The white paeony root extracting solution is prepared by the following method:

weighing proper amount of radix paeoniae alba coarse powder, heating and refluxing for extraction for 3 times: adding water 12-16 times the weight of the coarse powder of white peony root into the coarse powder of white peony root for the 1 st time, soaking for 0.5-1.5h, and extracting for 1.5-2.0h; adding water 10-14 times the weight of the white peony root coarse powder for the 2 nd time, and extracting for 1.0-1.5h; adding water 8-12 times the weight of the white peony root coarse powder in the 3 rd time, and extracting for 0.5-1.0h; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume 3-8 times of the weight of radix Paeoniae alba coarse powder to obtain radix Paeoniae alba extractive solution.

The volume of the filtrate is concentrated to 3-8 times of the mass of the radix paeoniae alba coarse powder in mL/g, namely the volume of the radix paeoniae alba extract obtained after each g of the radix paeoniae alba coarse powder is extracted by the method is 3-8mL.

The scutellaria baicalensis extracting solution is prepared by the following method:

weighing appropriate amount of Scutellariae radix coarse powder, heating and reflux extracting for 3 times: adding water 18-20 times the weight of the radix Scutellariae coarse powder at the 1 st time, soaking for 0.2-0.5 hr, and extracting for 1.0-1.5 hr; adding 14-16 times of water by mass of the radix Scutellariae coarse powder at the 2 nd time, and extracting for 1.0-1.5h; adding 11-15 times of water by mass of the radix Scutellariae coarse powder at the 3 rd time, and extracting for 0.5-1.0h; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to 8-12 times of the coarse powder mass of Scutellariae radix to obtain Scutellariae radix extractive solution.

The rhodiola rosea extracting solution is prepared by the following method:

weighing proper amount of rhodiola rosea coarse powder, heating and refluxing for extraction for 3 times: adding water 20-22 times the weight of radix Rhodiolae coarse powder at 1 time, soaking for 0.2-0.7 hr, and extracting for 1.5-2.0 hr; adding 16-18 times of water by mass of radix Rhodiolae coarse powder for the 2 nd time, and extracting for 1.0-1.5 hr; adding 10-12 times of water by mass of radix Rhodiolae coarse powder for 3 times, and extracting for 0.5-1.0 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume of 8-12 times of the mass of radix Rhodiolae coarse powder to obtain radix Rhodiolae extractive solution.

The frankincense extract is prepared by the following method:

weighing a proper amount of frankincense coarse powder, heating and refluxing the frankincense coarse powder for 3 times by using an ethanol solution with the volume concentration of 75 percent: adding 75% ethanol solution 15-18 times the mass of Olibanum coarse powder at 1 st time, soaking for 0.2-0.5 hr, and extracting for 1.0-1.8 hr; adding 75% ethanol solution with volume concentration 14-17 times the mass of Olibanum coarse powder for 2 times, and extracting for 0.8-1.2 hr; adding 75% ethanol solution 10-12 times the mass of Olibanum coarse powder for 3 times, and extracting for 0.5-1.0 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume 4-8 times of the mass of Olibanum coarse powder to obtain Olibanum extractive solution.

The propolis extract is prepared by the following method:

weighing a proper amount of propolis, and heating and refluxing the propolis by using an ethanol solution with the volume concentration of 75% for 3 times: adding 75% ethanol solution 22-24 times the weight of propolis, soaking for 0.2-0.5 hr, and extracting for 1.0-1.5 hr; adding 75% ethanol solution with volume concentration 18-20 times of propolis mass for 2 times, and extracting for 1.0-1.5 hr; adding 75% ethanol solution with volume concentration 14-16 times of propolis mass for 3 times, and extracting for 0.5-1.0 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume 6-10 times of propolis mass mL/g to obtain propolis extractive solution.

The garlic extract is prepared by the following method:

weighing appropriate amount of peeled and mashed garlic, heating and reflux extracting for 3 times: adding water 18-20 times the weight of mashed Bulbus Allii at 1 st time, soaking for 0.3-0.6 hr, and extracting for 1.2-2.0 hr; adding 14-18 times of water into mashed Bulbus Allii at the 2 nd time, and extracting for 1.0-1.5 hr; adding water 8-12 times of mashed Bulbus Allii in the 3 rd time, and extracting for 0.5-1.0 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume of 6-10 times of mashed Bulbus Allii mass/g to obtain Bulbus Allii extractive solution.

The magnolia bark extract is prepared by the following method:

weighing an appropriate amount of coarse magnolia bark powder, heating and refluxing the coarse magnolia bark powder by using an ethanol solution with the volume concentration of 65 percent for 3 times: soaking in 65% ethanol solution 16-20 times the weight of Magnolia officinalis coarse powder for 1 time for 0.2-0.4 hr, and extracting for 1.2-2.0 hr; extracting the 2 nd coarse powder with 10-14 times of 65% ethanol solution by volume for 1.0-1.5 hr; extracting 3 rd coarse powder with 65% ethanol solution with volume concentration 8-12 times of the coarse powder for 0.5-1.0 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to 6-10 times of the coarse powder mass of cortex Magnolia officinalis to obtain cortex Magnolia officinalis extractive solution.

The invention provides a preparation method of a mite-clearing acne-relieving anti-inflammation sterilization repair nourishing gel, which comprises the following steps:

a) Weighing 0.3-0.8g of Adiantum montanum oil, 0.03-0.08g of eucalyptus oil, 0.4-0.6g of evening primrose oil, 0.5-1.1g of peppermint oil, 0.03-0.08g of blumea oil, 0.2-0.6g of perilla seed oil, 0.5-1.0g of green Chinese prickly ash seed soaking oil, 0.4-0.8g of sea buckthorn fruit oil and 0.6-1.5g of lithospermum soaking oil, and uniformly stirring to obtain a mixed oil solution A for later use;

b) Weighing 1.0-2.0g of sodium alginate, adding into 20.0-33.0mL of distilled water, stirring, standing for 8.0-12.0h to fully swell, and obtaining uniform and transparent sodium alginate gel liquid for later use;

c) Weighing 0.8-1.5g of ice crystal forming agent AVC, adding into 50.0-83.0mL of distilled water, stirring uniformly, standing for 8.0-12.0h to fully swell, and obtaining uniform and transparent ice crystal forming agent AVC gel liquid for later use;

d) Weighing 1.5-2.0g of U30 cellulose thickener, adding into 29.0-56.0mL of distilled water, stirring uniformly, standing for 8.0-12.0h to fully swell to obtain uniform and transparent U30 cellulose thickener gel liquid for later use;

e) Weighing 0.29-0.50g of ethylparaben, adding 3.0-5.0mL of 1, 2-propylene glycol, and stirring for dissolving to obtain a preservative solution;

f) Weighing 1.0-1.5g of white paeony root extract, 0.5-1.0g of baical skullcap root extract, 0.4-0.6g of rhodiola rosea extract, 0.8-1.2g of frankincense extract, 0.5-1.5g of propolis extract, 0.7-1.5g of garlic extract, 1.0-2.0g of officinal magnolia bark extract, 0.5-1.2g of white vinegar and 0.2-0.5g of biological polysaccharide gum, and uniformly mixing to obtain a mixed solution B;

g) Adding the mixed oil solution A into the mixed solution B, and uniformly stirring to obtain a mixed solution C;

h) And adding the sodium alginate gel liquid, the ice crystal forming agent AVC gel liquid, the U30 cellulose thickening agent gel liquid and the preservative solution into the mixed solution C, and stirring and mixing uniformly to obtain the mite-clearing, acne-relieving, inflammation-diminishing, sterilizing, repairing and nourishing gel.

In the preparation process, the Adinandra milletii oil, the eucalyptus oil, the evening primrose oil, the peppermint oil, the blumea oil, the perilla seed oil, the green zanthoxylum seed soaking oil, the seabuckthorn fruit oil and the lithospermum soaking oil are weighed in the step a) to form a mixed oil solution A; step b) forming sodium alginate gel liquid; step c) forming an ice crystal forming agent AVC gel liquid; step d) forming a U30 cellulose thickener gel; step e) dissolving ethylparaben in 1, 2-propanediol to form a preservative solution; step f), weighing radix paeoniae alba extract, scutellaria baicalensis extract, rhodiola rosea extract, frankincense extract, propolis extract, garlic extract, mangnolia officinalis extract, white vinegar and biological polysaccharide gum, and uniformly mixing to form mixed liquid B; step g) adding the mixed oil solution A obtained in the step a) into the mixed solution B obtained in the step f), and uniformly stirring to form a mixed solution C rich in various extracts and functional components; and h) fully utilizing the thickening capability of the gel matrix and the capability of the gel matrix for carrying water-soluble functional components, and adding a preservative to obtain the mite-clearing, acne-relieving, anti-inflammation, sterilization, restoration and nourishing gel with fine and uniform texture.

The design concept of the components in the invention is as follows:

the Adonis amurensis oil contains a large amount of linoleic acid and oleic acid, can relieve skin allergy, is used for eczema, psoriasis and the like, can relieve symptoms of eczema, psoriasis and the like, and has good relieving and anti-inflammatory effects on closed acne and pox. The Adansonia dubia oil is rich in vitamins A, D, E and F, is easily and quickly absorbed by the skin, is fresh and non-greasy, and has the effects of highly moistening the skin, softening the cuticle and soothing the skin. Vitamins a and F have the effect of promoting regeneration of cellular tissues. Vitamin E is a good antioxidant, effective against aging. The Adansonia dubia oil can improve skin elasticity, promote skin cell tissue proliferation, repair skin without blocking pores, and effectively improve skin color while ensuring normal skin respiration.

The eucalyptus oil has cool skin feeling, has the effects of clearing away heat and toxic materials, diminishing inflammation, sterilizing, removing dampness and expelling toxin, and can effectively inhibit various bacteria and help the skin to kill other bacteria, thereby reducing the incidence rate of acne. For people suffering from acne, the oil can also accelerate the metabolism of skin, discharge substances harmful to the skin, accelerate the healing speed of acne muscle and avoid acne marks. Meanwhile, the eucalyptus oil can better relieve and treat the acne, enhance the immunity and regulate the endocrine function. It can also relieve inflammation of mild scald tissue and local necrosis of skin. The main component 1, 8-cineole has good lipid solubility, is easy to penetrate a biological membrane structure, is a good transdermal penetration enhancer, and is beneficial to the active substance component to penetrate through the epidermis and enter the dermis. The eucalyptus oil can eliminate hydroxyl free radical, and has antioxidant activity and anti-inflammatory effect, thereby improving inflammation symptoms and further playing a role in relieving acne.

The evening primrose oil contains 70% of linoleic acid, can effectively inhibit inflammation, and achieves the anti-inflammatory effect. It can be directly applied on skin for relieving skin allergy. Evening primrose oil also helps to regulate the production of hormones, so that the formation of acne can be prevented. The oil has high fatty acid content, and is helpful for diluting sebum and preventing pore blockage. Meanwhile, the evening primrose oil can nourish skin, beautify the face, reduce wrinkles and color spots and increase the skin elasticity.

The peppermint oil contains abundant menthol, has the effects of resisting inflammation, relieving pain and cooling skin, not only can bring cool feeling to the skin, but also can play the effects of contracting blood vessels, relieving acnes and calming the skin. The peppermint oil has the effects of diminishing inflammation, relieving pain, relieving itching, promoting blood circulation, relieving edema and the like when being externally used. The peppermint oil has the effects of cleaning and conditioning the skin, removing oil, sterilizing, preventing toxin from accumulating in skin pores, cleaning the pores, reducing oil secretion and enabling the skin to be fresh and cool when being applied to the skin.

The oleum folium Artemisiae Argyi is cool in nature, and has effects of clearing away heat and toxic materials, dispelling cold, stopping bleeding, resisting allergy, relieving pain, and relieving inflammation. The folium Artemisiae Argyi essential oil contains thujone, camphora, mugwort alcohol, caryophyllene, chamomile cycloalkene, etc. The oil has broad antibacterial spectrum, and has pharmacological effects of resisting oxidation, and enhancing immunity. The chamomile cycloalkene component contained in the blumea oil has the effects of calming and soothing. The blumea oil can promote blood circulation, has the effects of maintaining beauty and keeping young, and can comprehensively improve local skin to enable the skin to become fine and smooth after being used persistently.

The perilla seed oil is highly unsaturated natural oil, is mild in property and free of stimulation, contains rich nutritional ingredients such as vitamin C, potassium and iron, can effectively relieve the allergic condition of facial skin, smoothes fine lines on the face, makes the skin tender, and can promote the regression of pox and inhibit the generation of the pox. The perilla seed oil can obviously improve the activity of superoxide dismutase in red blood cells and has obvious effect of delaying the aging of organisms. In addition, the perilla seed oil can penetrate into the skin, inhibit the generation of melanin, strengthen the immunity and repair function, strengthen the skin metabolism, discharge the melanin in the skin, brighten the skin color and delay the aging. It contains natural antibacterial factor, and has effects of tranquilizing skin and inhibiting acne generation.

The phellandrene and linalool contained in the green pepper have high insecticidal activity, have the effects of sterilization and disinsection, and have a certain killing effect on some hemolytic streptococcus and staphylococcus aureus. Besides fatty acid and protein, the green pricklyash seed oil also contains rich Ca, fe, mg, zn and minerals with high contents of Sr, mn and the like which are necessary for human bodies. The content of calcium can influence the antioxidation capability of human skin, and the calcium is a trace element which cannot be lacked by the health of the skin, so that the calcium can not only help to improve the barrier capability of the skin, but also effectively increase the moisturizing capability of the skin. The magnesium element can increase the firmness of the skin and accelerate the metabolism of the skin. The mite inhibiting agent in the green pricklyash peel can cause nucleic acid chain breaking in a mite body, and effectively remove the mites. In addition, the green pricklyash seed also has the effects of dispelling cold, relieving pain and itching. The adoption of the mode of soaking the seabuckthorn fruit oil is beneficial to enhancing the moistening effect of the green pepper seeds while exerting the self effect, and exerts the effects of resisting bacteria and diminishing inflammation, clearing mites and relieving acne together with the seabuckthorn fruit oil.

The fructus Hippophae oil contains fructus Hippophae flavone, carotene, carotenoid, phospholipid compound, vitamin E, mineral selenium, etc. These substances can enhance antioxidant effect, promote microcirculation, repair skin cells, and accelerate skin metabolism. The vitamin C rich in the vitamin C can effectively inhibit the deposition of abnormal pigment on the skin, thereby reducing the formation of melanin and effectively whitening the skin. In addition, the seabuckthorn fruit oil has obvious effects of eliminating free radicals, resisting oxidation and delaying senility, can effectively remove facial color spots and wrinkles, has various effects of moistening, whitening, removing freckles, removing wrinkles and the like, and can further reduce various skin diseases caused by aging. The fructus Hippophae oil also has hemostatic and wound healing promoting effects. The composition can be applied to cleaned wound to accelerate hemostasis and promote wound healing, thereby promoting healing of damaged acne. The sea buckthorn fruit oil can also resist skin chapping in winter, and has the effects of diminishing inflammation, sterilizing and reducing swelling.

Radix Arnebiae has antifungal and antiviral effects, and can destroy the growth environment of acarid, thereby has good antiinflammatory effect, and can be used for treating measles without adequate eruption, epidemic febrile disease, macula, pyocutaneous disease, eczema, scald, etc. The lithospermum is mainly used as an antioxidant and an anti-inflammatory agent, can delay skin aging and keep skin vitality, has low risk factor, is relatively safe and can be used safely, and the lithospermum does not cause acne. In addition, the lithospermum has the effects of moisturizing and moisturizing the skin, relieving swelling and itching and relieving the problem of dry skin. It has effects of removing acne, promoting blood circulation, removing blood stasis, and accelerating acne and scar fading. The lithospermum is extracted by adopting a tea seed oil soaking method, so that the functional components of the lithospermum are not damaged, and meanwhile, the lithospermum and the tea seed oil can perform synergistic action to play the effects of sterilizing and nourishing the skin.

The tea seed oil is rich in vitamins A, B, D and E, carotene and other antioxidants, and can protect skin, make skin fine and glossy, and prevent skin injury and aging. The tea seed oil can also be used for treating skin diseases such as burn, scald, tinea corporis and eczema. In addition, the tea seed oil can also play a role in removing wrinkles, fading color spots and freckles, moistening the skin and also has the effect of resisting allergy. It also has effects in clearing away heat and toxic materials, relieving inflammation, relieving swelling, moistening skin, and caring skin. The tea seed oil has the functions of sterilizing and enhancing immunity, and can effectively treat acnes when being used together with other components in the invention.

The biological polysaccharide gum is a linear polysaccharide viscous solution, has good sensory advantages and moisturizing effect, and is a good 'active excipient'. The good film forming properties of the biopolysaccharide gums are due to the high molecular weight polysaccharides, which enhance their moisturizing effect due to their "water-absorbing" capacity. Since the biopolysaccharide gums are more readily degraded by skin enzymes into smaller molecular sugars to capture water molecules, they provide greater hydration to the skin, accelerate sebum barrier repair and reduce transepidermal water loss. The polysaccharide gum competitively inhibits macrophage migration inhibitory factor, thereby accelerating sebum barrier repair. The addition of the biological polysaccharide gum ensures that each component of the product is more stable, and enhances the effects of repair and moisture preservation.

The white vinegar is beneficial to the loosening and removal of old cutin on the surface of the skin, and has the effects of slight peeling and skin rejuvenation. It also has mild irritation to skin, and is beneficial to skin metabolism. The main component of the white vinegar is acetic acid, which is a weakly acidic substance and has the function of killing fungi and bacteria. The white vinegar can be applied on skin to make skin smoother, finer and glossy. The weakly acidic substance has slight excitation and stimulation effects on skin vascular nerves, can accelerate facial blood circulation and cell metabolism, and is beneficial to skin beautification and anti-aging. The gel is added with white vinegar, so that the gel can be synergistically acted with other functional components to further play the functions of inhibiting bacteria and tendering skin.

The white peony root has strong antibacterial property, and has certain inhibiting effect on staphylococcus aureus, escherichia coli, pseudomonas aeruginosa, proteus vulgaris, trichophyton violaceum, trichophyton concentricum, yellow ringworm, ozokerite ringworm, microsporum ferrugineum and other bacteria and fungi. Therefore, it has good bactericidal action. Meanwhile, it can inhibit the generation of elastase and nitric oxide, eliminate free radicals, promote the activity of tissue protease and the like, thereby playing a role in delaying aging and activating skin vitality. Radix Paeoniae alba can be used for treating acne and delaying skin aging. In addition, the white paeony root has the whitening effect on the skin and also has a certain improvement effect on rough skin. Radix Paeoniae alba in combination with white vinegar can be used for treating facial freckle, chloasma and melanin pigmentation. Meanwhile, the medicine also has certain curative effect on removing skin acnes. By adopting a water extraction mode, the extraction rate of the effective components of the white paeony root can be improved, and the white paeony root can be combined with other effective components to play the effects of sterilizing and nourishing the skin.

Scutellariae radix has inhibitory effect on multiple gram-positive bacteria and gram-negative bacteria, and baicalein has stronger effect than glycoside in anti-allergic reaction. The Scutellariae radix can absorb ultraviolet ray, and has certain repairing effect on sunburned skin. The scutellaria has strong antioxidant activity, can eliminate oxygen free radicals, inhibit the generation of melanin and brighten skin color. The radix Scutellariae can also enhance skin metabolism, increase skin elasticity, and relieve wrinkle. In addition, huang Qin can also "purge lung fire and relieve muscle heat", and achieve the purpose of removing damp-heat, clearing blood heat and clearing heat-toxin through its efficacy of purging fire, clearing heat and drying dampness, so it is good at treating damp-heat induced damage diseases, such as facial acne, skin sore and tinea etc. Bai Qin can also dry dampness, cold can clear heat, excels at clearing damp-heat from the upper energizer, and also can treat various dermatitis such as eczema and scabies caused by damp-heat. Extracting Scutellariae radix with water can fully enrich its effective components, and has antibacterial and skin caring effects.

The rhodiola rosea can inhibit the activity of tyrosinase and reduce the catalysis speed of the tyrosinase, thereby reducing the generation of skin melanin, improving the skin pigmentation state and achieving the whitening effect. The rhodiola rosea can absorb light energy under the illumination condition and convert the light energy into energy which is nontoxic to cells, thereby protecting the cells. Salidroside can obviously inhibit increase of inflammatory cytokine caused by ultraviolet irradiation, and has obvious repairing effect on skin ultraviolet radiation injury. In addition, the rhodiola rosea extract can also promote the secretion of collagen, thereby achieving the effect of resisting aging. The rhodiola rosea also has the effects of absorbing water and preserving moisture, and manganese ions contained in the rhodiola rosea can promote the activity of polysaccharide polymerase, inhibit the generation of wrinkles in vivo and the decomposition of collagen, inhibit inflammatory reaction caused by sunshine, regulate the excretion and absorption functions of skin and further promote the metabolism of the skin. The gel adopts water extraction to obtain effective components of radix Rhodiolae, and can protect salidroside from damage, and fully exert the effects of radix Rhodiolae in repairing and nourishing skin.

The frankincense has good activation effect on a peroxidase-activated receptor, plays an important role in the healing process of skin injury, has good anti-inflammatory effect, and can prevent and treat skin redness. Olibanum has effect in promoting activation of caspase, and can prolong cell life, thereby having antiaging effect. Meanwhile, the skin whitening oil can whiten the skin and condition oily skin. Frankincense, pungent and bitter in flavor and warm in nature, enters spleen and heart meridians and can also activate blood and promote qi circulation, relieve swelling and promote tissue regeneration, remove blood stasis and relieve pain. The frankincense also has the effects of easing pain and diminishing inflammation, has obvious anti-inflammatory effect on the formaldehyde arthritis of the mice, and can promote the increase of multinucleated white blood cells so as to phagocytose dead blood cells and cells, thereby improving metabolism. Mastic may also be given to the aging skin for its new life, to thin lines, and to smooth wrinkles. Meanwhile, the skin elasticity can be recovered, pores can be tightened, and looseness can be improved. It also has astringent properties to balance oily skin, and is especially beneficial to dry, inflamed, and sensitive skin, and has effects on wound, ulcer, and inflammation. The frankincense is extracted by 75% ethanol, so that the effective components in the frankincense can be better obtained, and the anti-inflammation and repair effects of the frankincense can be fully exerted.

The alkene and terpenoid compounds in the propolis have various biological activities, and are the main sources of nourishing components in the aspect of skin care. The flavonoid and terpene substances in the propolis have strong inhibiting and killing effects on various bacteria, fungi, viruses and other microorganisms, thereby playing an anti-inflammatory effect and effectively inhibiting the growth of mites. Meanwhile, the flavonoid in the propolis can promote the synthesis of collagen, help the repair of skin tissues, reduce inflammatory reaction, accelerate wound healing and achieve the effect of fading scars. Propolis also has good antioxidant effect, and can scavenge free radicals and eliminate excessive active oxygen due to obesity and overwork. The alcohol extraction method is adopted, so that the effective substances in the propolis can be fully enriched, and meanwhile, the propolis composition is compounded with other products, and the effects of resisting inflammation, sterilizing and nourishing the skin are better exerted.

Garlic contains abundant nutrients such as protein, oligosaccharide and polysaccharide, and has effects of promoting blood circulation, and relieving aging of blood vessel and skin. In addition, the garlic is rich in sulfide and has certain effects of sterilization, bacteriostasis and anti-aging. In addition, garlic contains a certain amount of allicin, which is called vegetative natural broad-spectrum antibiotic and has obvious inhibiting and killing effects on various pathogenic bacteria. Garlic also smoothes wrinkles and resists aging because it contains an antioxidant substance in the body that effectively counteracts aging. In addition, garlic has the effects of beautifying and protecting skin, has the effects of stimulating peripheral nerves, improving epidermal blood circulation, enhancing skin activity, activating reticular cells and promoting metabolism on the skin, and can enable the skin to be more moist, smooth and fine. The garlic water has good killing effect on pathogenic bacteria and parasites. Therefore, the sterilization and skin care effects of the garlic can be better exerted by adopting a water extraction mode of the garlic.

The magnolia officinalis is bitter and pungent in taste and warm in nature, has the effects of promoting qi circulation, drying dampness, removing food retention and removing mites, and has a certain antibacterial effect. Cortex Magnolia officinalis has in vitro inhibitory effect on a number of dermatophytes, and also has anti-inflammatory effect. In addition, the Magnolia officinalis water extract has strong antibacterial effect on staphylococcus and streptococcus, and also has inhibitory effect on dermatophytes such as trichophyton violaceum, trichophyton concentricum and trichophyton rubrum, and can effectively dispel mites and relieve and prevent acne. Cortex magnoliae officinalis is commonly used as an antioxidant, an antibacterial agent and an anti-inflammatory agent, and is relatively safe and free of acne-causing property. Cortex Magnolia officinalis has antibacterial effect, and can be used for treating acne by combining with its antiinflammatory effect, and it has antioxidant effect, and has effects of scavenging free radicals and resisting aging. The magnolia bark extract is obtained by adopting an alcohol extraction mode, so that the functional components of the magnolia bark extract can be fully enriched, and the anti-inflammatory and bactericidal effects of the magnolia bark extract can be further exerted.

The ice crystal former AVC is a synthetic polymer, commonly used as gelling agent for transparent systems and as thickener for oil-in-water emulsions. The polymer is convenient to use, good in dispersibility, fast to absorb and good in stability even without an emulsifier, can enable the product to look light and thin, but has certain viscosity, and brings comfortable use feeling. The polymer is stable under the irradiation of ultraviolet rays. The ice crystal forming agent AVC has good rheological property and stability, is crystal clear, light, thin and mild in texture, can be used as a thickening agent and a gelling agent, and can bring soft and comfortable touch to the skin.

The U30 cellulose thickener is soluble in water, can be compounded with various surfactants, has antistatic and conditioning effects, is an ideal smoothing agent and thickener in natural cosmetics, and has multiple functions of thickening, colloid stabilization, water retention, antistatic, wetting, smoothing and the like. The U30 cellulose thickener has the ability of repairing damaged protein matrix, can reduce the irritation of surfactant, recover the barrier function of skin, bring comfortable after-use feeling to skin, and make skin moist and smooth.

Sodium alginate is a natural polysaccharide with high water solubility, can form a viscous uniform solution, and is commonly used as a stabilizer, a thickener, an emulsifier, a dispersant and a gelling agent. The product is rich in anions, and has effects in promoting skin metabolism, stimulating fibroblast to generate more colloid, elastin, mucopolysaccharide, etc., promoting epidermal cell growth, promoting metabolism, and preventing skin aging. Therefore, the addition of the sodium alginate is beneficial to the formation and the stability of a gel system, and can also improve the moisture retention of the skin and make the skin tender and smooth.

The eucalyptus oil has a strong antibacterial effect, can improve inflammation symptoms and has the effect of relieving acne; the evening primrose oil can inhibit inflammation and effectively prevent acne; the oleum Menthae Dementholatum can be sterilized and deoiled; the blumea oil can relieve pain, resist inflammation, detoxify and inhibit bacteria; the perilla seed oil contains natural bacteriostatic factors, and can calm skin and inhibit acne; the green pricklyash seed contains the acarus-inhibiting essence, and can kill insects and dry dampness; the white peony root has good bactericidal effect; the lithospermum is a good anti-inflammatory agent and can remove acne; the scutellaria baicalensis has an inhibiting effect on various skin pathogenic fungi; the rhodiola rosea can obviously inhibit the increase of inflammatory cytokines caused by ultraviolet irradiation; the propolis can reduce inflammatory reaction, and can effectively inhibit bacteria and kill mites; the garlic has wide antimicrobial spectrum and strong bactericidal power; cortex Magnolia officinalis has effects of eliminating dampness and phlegm, and resisting bacteria and removing mite. The components are compounded synergistically, so that the gel can effectively remove mites, has the functions of resisting inflammation and bacteria and relieves acne inflammation.

The Adina rubella oil has high moistening and skin repairing effects; the tea seed oil can enhance immunity and moisten skin; the seabuckthorn fruit oil can accelerate skin metabolism and help the healing of damaged acne; the white vinegar can accelerate blood circulation and cell metabolism and help to repair skin; the frankincense has good anti-inflammatory property and plays an important role in the healing process of skin injury; the biological polysaccharide gum has good sensory advantages and moisturizing effect. The components are used cooperatively, and play a role in inhibiting bacteria, diminishing inflammation, repairing damaged skin barriers and nourishing the skin.

The ice crystal forming agent AVC, the U30 cellulose thickener and the sodium alginate have synergistic effect, and the gel is endowed with safe and mild properties, fine and uniform texture, light moisture, refreshing and non-sticky feeling. The anti-corrosion system, the thickening agent system and the functional components are cooperated to endow the anti-acne anti-inflammation sterilization repair nourishing gel with the effects of safety, no stimulation, mild water moistening, antibiosis, mite removal, acne relief and skin repair.

The product mainly utilizes functional vegetable oil and natural plant extract, different components respectively play roles, and an adjusting system is used for increasing the stability of the product, so that the effect is exerted in a synergistic manner, and the product is safe, mild and non-irritant; the components cooperatively play the efficacies of removing mites, diminishing inflammation, relieving acne, cleaning skin and nourishing muscles.

Compared with the prior art, the anti-mite, anti-inflammation, sterilization, restoration and nourishing gel for clearing mites, relieving acne, repairing skin contains various natural plants and traditional Chinese medicinal material effective components, can effectively kill the mites, reduce the generation of acnes, and can shrink pores, keep the pores smooth, tighten skin and control the secretion of grease. The gel has the effects of long-acting mite killing, sterilization and acne alleviation, and also has the effects of repairing, nourishing and cleaning skin, so that the skin is bright, white, tender, mild and rejuvenating.

Drawings

Fig. 1 is a photograph of the mite-clearing, acne-alleviating, anti-inflammatory, bactericidal, repairing and nourishing gel of the present invention.

Detailed Description

The present invention will be further described with reference to the following examples.

According to the specification of pharmacopoeia, in the preparation process of the invention, the coarse powder can completely pass through a No. two sieve, but is mixed with powder which can pass through a No. four sieve by no more than 40%; the ethanol concentration used is the volume concentration and all the heat extractions are carried out under slightly boiling conditions.

Example 1

1.1 preparation of Green Zanthoxylum bungeanum seed soaking oil

Weighing a proper amount of green pepper seed coarse powder, adding seabuckthorn fruit oil which is 3 times the weight of the green pepper seed coarse powder, soaking for 3 days, performing ultrasonic extraction with the ultrasonic power of 300W, heating to 35 ℃, performing ultrasonic extraction for 1.0h, filtering, and taking filtrate to obtain green pepper seed soaking oil for later use.

1.2 preparation of Lithospermum erythrorhizon immersion oil

Weighing a proper amount of gromwell coarse powder, adding tea seed oil with the weight of 8 times of the gromwell coarse powder, hermetically soaking for 5 days, carrying out ultrasonic extraction with the ultrasonic power of 300W, heating to 40 ℃, carrying out ultrasonic extraction for 1.0h, filtering, and taking filtrate to obtain gromwell soaking oil for later use.

1.3 preparation of white peony root extract

Weighing proper amount of radix paeoniae alba coarse powder, heating and refluxing for extraction for 3 times: adding water 13 times the weight of the white peony root coarse powder into the water at the 1 st time, soaking for 0.6h, and extracting for 1.5h; adding water 10 times the weight of the white peony root coarse powder for the 2 nd time, and extracting for 1.0h; adding water with the mass of 8 times of that of the white paeony root coarse powder in the 3 rd time, and extracting for 0.6h; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to 4 times of the mass of radix Paeoniae alba coarse powder (mL/g) to obtain radix Paeoniae alba extractive solution.

1.4 preparation of Scutellaria baicalensis Georgi extract

Weighing appropriate amount of Scutellariae radix coarse powder, heating and reflux extracting for 3 times: adding water with the amount of 18 times of the weight of the baical skullcap root coarse powder for 1 time, soaking for 0.3h, and extracting for 1.2h; adding 14 times of water by mass of the radix Scutellariae coarse powder for 2 times, and extracting for 1.0 hr; adding 11 times of water by mass of the coarse powder of radix Scutellariae at the 3 rd time, and extracting for 0.6h; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume 9 times mL/g of Scutellariae radix coarse powder to obtain Scutellariae radix extractive solution.

1.5 preparation of rhodiola rosea extract

Weighing proper amount of rhodiola rosea coarse powder, heating and refluxing for extraction for 3 times: adding water 20 times the weight of radix Rhodiolae coarse powder at 1 time, soaking for 0.3 hr, and extracting for 1.5 hr; adding 16 times of water by mass of the rhodiola rosea coarse powder for 2 times, and extracting for 1.2h; adding 11 times of water by mass of the rhodiola rosea coarse powder for 3 times, and extracting for 0.5h; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to 8 times of the mass of radix Rhodiolae coarse powder to obtain radix Rhodiolae extractive solution.

1.6 preparation of Olibanum extract

Weighing a proper amount of frankincense coarse powder, heating and refluxing the frankincense coarse powder for 3 times by using an ethanol solution with the volume concentration of 75 percent: adding 75% ethanol solution 15 times the mass of Olibanum coarse powder at 1 time, soaking for 0.5 hr, and extracting for 1.0 hr; adding 75% ethanol solution with volume concentration 14 times the mass of the Olibanum coarse powder for 2 times, and extracting for 0.8h; adding 75% ethanol solution with volume concentration 10 times the mass of the Olibanum coarse powder for 3 times, and extracting for 0.6h; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to 4 times of the mass of Olibanum coarse powder to obtain Olibanum extractive solution.

1.7 preparation of propolis extract

Weighing a proper amount of propolis, and heating and refluxing the propolis by using an ethanol solution with the volume concentration of 75% for 3 times: adding 75% ethanol solution with 22 times of propolis mass volume concentration for 1 time, soaking for 0.2 hr, and extracting for 1.0 hr; adding 75% ethanol solution with 18 times of propolis mass volume concentration for 2 times, and extracting for 1.0 hr; adding 75% ethanol solution with 14 times of propolis mass volume concentration for 3 times, and extracting for 0.5 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to 6 times of the mass of propolis (mL/g) to obtain propolis extractive solution.

1.8 preparation of Garlic extract

Weighing appropriate amount of peeled and mashed garlic, heating and reflux extracting for 3 times: adding water with the amount of 18 times of the mashed garlic for 1 time, soaking for 0.4h, and extracting for 1.2h; adding 14 times of water into the mashed garlic for the 2 nd time, and extracting for 1.0h; adding water 8 times of mashed Bulbus Allii in the 3 rd time, and extracting for 0.5 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to 6 times of the mashed garlic mass (mL/g) to obtain Bulbus Allii extractive solution.

1.9 preparation of Magnolia bark extract

Weighing an appropriate amount of coarse magnolia bark powder, heating and refluxing the coarse magnolia bark powder by using an ethanol solution with the volume concentration of 65 percent for 3 times: soaking in 65% ethanol solution with 16 times of the coarse powder for 1 time, and extracting for 1.2 hr; extracting the 2 nd time coarse magnolia powder with 10 times of ethanol solution with volume concentration of 65% for 1.0h; extracting 3 rd time with 65% ethanol solution with volume concentration 8 times of the coarse powder for 0.55 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to 6 times of the mass of cortex Magnolia officinalis coarse powder to obtain cortex Magnolia officinalis extract.

1.10 preparation method of mite-clearing acne-relieving anti-inflammation sterilization repair nourishing gel comprises the following steps

a) Weighing 0.3g of Adiantum montanum oil, 0.03g of eucalyptus oil, 0.45g of evening primrose oil, 0.52g of peppermint oil, 0.038g of blumea oil, 0.2g of perilla seed oil, 0.5g of green pepper seed soaking oil, 0.4g of sea buckthorn fruit oil and 0.6g of lithospermum soaking oil, and uniformly stirring to obtain a mixed oil solution A for later use;

b) Weighing 1.0g of sodium alginate, adding the sodium alginate into 20.0mL of distilled water, stirring uniformly, standing for 8.0h to fully swell the sodium alginate, and obtaining uniform and transparent sodium alginate gel liquid for later use;

c) Weighing 0.8g of an ice crystal forming agent AVC, adding into 50.0mL of distilled water, stirring uniformly, standing for 8.0h to fully swell the mixture, and obtaining a uniform and transparent gel solution of the ice crystal forming agent AVC for later use;

d) Weighing 1.5g of U30 cellulose thickener, adding into 29.0mL of distilled water, stirring uniformly, standing for 8.0h to fully swell the mixture to obtain uniform and transparent U30 cellulose thickener gel liquid for later use;

e) Weighing 0.29g of ethylparaben, adding 3.0mL of 1, 2-propylene glycol, and stirring for dissolving to obtain a preservative solution;

f) Weighing 1.0g of white paeony root extract, 0.5g of baical skullcap root extract, 0.4g of rhodiola rosea extract, 0.8g of frankincense extract, 0.55g of propolis extract, 0.72g of garlic extract, 1.0g of officinal magnolia bark extract, 0.5g of white vinegar and 0.2g of biological polysaccharide gum, and uniformly mixing to obtain a mixed solution B;

Example 2

2.1 preparation of Green Zanthoxylum bungeanum seed soaking oil

Weighing a proper amount of green pepper seed coarse powder, adding sea buckthorn fruit oil with the mass of 4 times of the green pepper seed coarse powder, soaking for 5 days, carrying out ultrasonic extraction with the ultrasonic power of 400W, heating to 50 ℃, carrying out ultrasonic extraction for 1h, filtering, and taking filtrate to obtain green pepper seed soaking oil for later use;

2.2 preparation of Lithospermum erythrorhizon immersion oil

Weighing a proper amount of lithospermum coarse powder, adding tea seed oil with the weight of 9 times of the lithospermum coarse powder, sealing and soaking for 6 days, carrying out ultrasonic extraction with the ultrasonic power of 500W, heating to 45 ℃, carrying out ultrasonic extraction for 1.5h, filtering, and taking filtrate to obtain lithospermum soaking oil for later use.

2.3 preparation of white peony root extract

Weighing proper amount of radix paeoniae alba coarse powder, heating and refluxing for extraction for 3 times: adding water 15 times the weight of the white peony root coarse powder for the 1 st time, soaking for 1.0h, and extracting for 1.7h; adding 12 times of water by mass of the white peony root coarse powder in the 2 nd time, and extracting for 1.2h; adding water 9 times the weight of the white peony root coarse powder in the 3 rd time, and extracting for 0.7h; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume of 4.5 times mL/g of radix Paeoniae alba coarse powder to obtain radix Paeoniae alba extractive solution.

2.4 preparation of Scutellaria baicalensis Georgi extract

Weighing appropriate amount of Scutellariae radix coarse powder, heating and reflux extracting for 3 times: adding water 19 times the weight of the Scutellariae radix coarse powder at 1 st time, soaking for 0.3 hr, and extracting for 1.2 hr; adding water 15 times the weight of the Scutellariae radix coarse powder for 2 times, and extracting for 1.2 hr; adding 12 times of water by mass of the radix Scutellariae coarse powder at the 3 rd time, and extracting for 0.7 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume 9 times mL/g of Scutellariae radix coarse powder to obtain Scutellariae radix extractive solution.

2.5 preparation of rhodiola root extract

Weighing proper amount of rhodiola rosea coarse powder, heating and refluxing for extraction for 3 times: adding water with the amount of 21 times of the mass of the rhodiola rosea coarse powder for 1 time, soaking for 0.5h, and extracting for 1.7h; adding water 17 times the weight of the rhodiola rosea coarse powder for 2 times, and extracting for 1.2h; adding 11 times of water by mass of the rhodiola rosea coarse powder for 3 times, and extracting for 0.7h; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume of 9 times mL/g of radix Rhodiolae coarse powder to obtain radix Rhodiolae extractive solution.

2.6 preparation of Olibanum extract

Weighing a proper amount of frankincense coarse powder, heating and refluxing the frankincense coarse powder for 3 times by using an ethanol solution with the volume concentration of 75 percent: adding 75% ethanol solution with volume concentration 16 times the mass of the frankincense coarse powder at the 1 st time, soaking for 0.3h, and extracting for 1.2h; adding 75% ethanol solution 15 times the mass of Olibanum coarse powder for 2 times, and extracting for 0.9 hr; adding 75% ethanol solution with 11 times of the mass of the Olibanum coarse powder at the 3 rd time, and extracting for 0.7h; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to 5 times of the mass of Olibanum coarse powder to obtain Olibanum extractive solution.

2.7 preparation of propolis extract

Weighing a proper amount of propolis, and heating and refluxing the propolis by using an ethanol solution with the volume concentration of 75% for 3 times: adding ethanol solution with volume concentration of 75% 23 times of propolis mass for 1 time, soaking for 0.3 hr, and extracting for 1.2 hr; adding ethanol solution with volume concentration of 75% 19 times of propolis mass for 2 times, and extracting for 1.2 hr; adding 75% ethanol solution 15 times the weight of propolis at volume concentration for 3 times, and extracting for 0.6 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume 7 times mL/g of propolis mass to obtain propolis extractive solution.

2.8 preparation of Garlic extract

Weighing appropriate amount of peeled and mashed garlic, heating and reflux extracting for 3 times: adding water with 19 times of the mass of mashed garlic in the 1 st time, soaking for 0.4h, and extracting for 1.4h; adding water 15 times the weight of mashed Bulbus Allii in the 2 nd time, and extracting for 1.2 hr; adding water 9 times of mashed Bulbus Allii in the 3 rd time, and extracting for 0.7 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume of 8 times mL/g of mashed Bulbus Allii to obtain Bulbus Allii extractive solution.

2.9 preparation of Magnolia bark extract

Weighing an appropriate amount of coarse magnolia bark powder, heating and refluxing the coarse magnolia bark powder by using an ethanol solution with the volume concentration of 65 percent for 3 times: soaking in 65% ethanol solution with 17 times of the coarse powder for 1 time, and extracting for 1.4 hr; extracting 2 nd time of 65% ethanol solution with volume concentration 12 times of the coarse powder for 1.1 hr; extracting 3 rd time with 65% ethanol solution with 11 times of the coarse powder mass and volume concentration for 0.7 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume 7 times mL/g of cortex Magnolia officinalis coarse powder to obtain cortex Magnolia officinalis extract.

2.10 preparation method of mite-clearing acne-relieving anti-inflammation sterilization repair nourishing gel comprises the following steps

a) Weighing 0.5g of Adiantum montanum oil, 0.05g of eucalyptus oil, 0.5g of evening primrose oil, 0.7g of peppermint oil, 0.06g of blumea oil, 0.4g of perilla seed oil, 0.7g of green pepper seed soaking oil, 0.6g of sea buckthorn fruit oil and 0.8g of lithospermum soaking oil, and uniformly stirring to obtain a mixed oil solution A for later use;

b) Weighing 1.5g of sodium alginate, adding into 26.0mL of distilled water, stirring uniformly, standing for 9.0h to fully swell the sodium alginate to obtain a uniform and transparent sodium alginate gel solution for later use;

c) Weighing 0.9g of ice crystal forming agent AVC, adding into 63.0mL of distilled water, stirring uniformly, standing for 9.0h to fully swell, and obtaining uniform and transparent ice crystal forming agent AVC gel liquid for later use;

d) Weighing 1.6g of U30 cellulose thickener, adding into 35.0mL of distilled water, stirring uniformly, standing for 9.0h to fully swell the mixture to obtain uniform and transparent U30 cellulose thickener gel liquid for later use;

e) Weighing 0.35g of ethylparaben, adding 4.0mL of 1, 2-propylene glycol, and stirring for dissolving to obtain a preservative solution;

f) Weighing 1.2g of white paeony root extract, 0.8g of baical skullcap root extract, 0.5g of rhodiola rosea extract, 0.9g of frankincense extract, 0.7g of propolis extract, 0.9g of garlic extract, 1.4g of officinal magnolia bark extract, 0.7g of white vinegar and 0.3g of biological polysaccharide gum, and uniformly mixing to obtain a mixed solution B;

Example 3

3.1 preparation of Green Zanthoxylum bungeanum seed soaking oil

Weighing a proper amount of green pepper seed coarse powder, adding sea buckthorn fruit oil which is 5 times the weight of the green pepper seed coarse powder, soaking for 6 days, carrying out ultrasonic extraction with the ultrasonic power of 600W, heating to 60 ℃, carrying out ultrasonic extraction for 3.0h, filtering, and taking filtrate to obtain green pepper seed soaking oil for later use;

3.2 preparation of Lithospermum erythrorhizon immersion oil

Weighing a proper amount of lithospermum coarse powder, adding tea seed oil with the weight of 10 times of the lithospermum coarse powder, sealing and soaking for 7 days, carrying out ultrasonic extraction with the ultrasonic power of 600W, heating to 60 ℃, carrying out ultrasonic extraction for 3.0h, filtering, and taking filtrate to obtain lithospermum soaking oil for later use.

3.3 preparation of white peony root extract

Weighing proper amount of radix paeoniae alba coarse powder, heating and refluxing for extraction for 3 times: adding 16 times of water by mass of the white peony root coarse powder into the water at the 1 st time, soaking for 1.5h, and extracting for 2.0h; adding 14 times of water by mass of the white peony root coarse powder in the 2 nd time, and extracting for 1.5h; adding 12 times of water by mass of the white peony root coarse powder in the 3 rd time, and extracting for 1.0h; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to 8 times of the mass of radix Paeoniae alba coarse powder (mL/g) to obtain radix Paeoniae alba extractive solution.

3.4 preparation of Scutellaria baicalensis Georgi extract

Weighing appropriate amount of Scutellariae radix coarse powder, heating and reflux extracting for 3 times: adding water 19 times the weight of Scutellariae radix coarse powder at 1 st time, soaking for 0.5 hr, and extracting for 1.5 hr; adding water with the amount of 16 times of the weight of the radix scutellariae coarse powder for 2 times, and extracting for 1.5h; adding water 15 times the weight of the radix Scutellariae coarse powder at the 3 rd time, and extracting for 1.0h; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume 12 times mL/g of Scutellariae radix coarse powder to obtain Scutellariae radix extractive solution.

3.5 preparation of rhodiola root extract

Weighing proper amount of rhodiola rosea coarse powder, heating and refluxing for extraction for 3 times: adding 22 times of water by mass of the rhodiola rosea coarse powder for 1 time, soaking for 0.7h, and extracting for 2.0h; adding water with the amount of 18 times of the rhodiola rosea coarse powder for 2 times, and extracting for 1.5h; adding 12 times of water by mass of the rhodiola rosea coarse powder for 3 times, and extracting for 1.0h; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume of 12 times mL/g of radix Rhodiolae coarse powder to obtain radix Rhodiolae extractive solution.

3.6 preparation of Olibanum extract

Weighing a proper amount of frankincense coarse powder, heating and refluxing the frankincense coarse powder for 3 times by using an ethanol solution with the volume concentration of 75 percent: adding 75% ethanol solution with the volume concentration 18 times the mass of the frankincense coarse powder at the 1 st time, soaking for 0.5h, and extracting for 1.8h; adding 75% ethanol solution with 17 times of the mass of the Olibanum coarse powder for 2 times, and extracting for 1.2 hr; adding 75% ethanol solution with volume concentration 12 times the mass of the Olibanum coarse powder for 3 times, and extracting for 1.0h; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to 8 times of the mass of Olibanum coarse powder to obtain Olibanum extractive solution.

3.7 preparation of propolis extract

Weighing a proper amount of propolis, and heating and refluxing the propolis by using an ethanol solution with the volume concentration of 75% for 3 times: adding 75% ethanol solution with volume concentration 24 times of propolis mass for the 1 st time, soaking for 0.5 hr, and extracting for 1.5 hr; adding 75% ethanol solution with 20 times of propolis mass volume concentration for 2 times, and extracting for 1.5 hr; adding 75% ethanol solution with 16 times of propolis mass volume concentration for 3 times, and extracting for 1.0 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume 10 times mL/g of propolis mass to obtain propolis extractive solution.

3.8 preparation of Garlic extract

Weighing appropriate amount of peeled and mashed garlic, heating and reflux extracting for 3 times: adding water 20 times the mass of mashed garlic in the 1 st time, soaking for 0.6h, and extracting for 1.9h; adding 18 times of water into the mashed garlic for the 2 nd time, and extracting for 1.5h; adding 12 times of water into mashed Bulbus Allii at 3 rd time, and extracting for 1.0 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume of 10 times mL/g of mashed Bulbus Allii to obtain Bulbus Allii extractive solution.

3.9 preparation of Magnolia bark extract

Weighing an appropriate amount of coarse magnolia bark powder, heating and refluxing the coarse magnolia bark powder by using an ethanol solution with the volume concentration of 65 percent for 3 times: soaking in 65% ethanol solution 20 times the weight of Magnolia officinalis coarse powder for 1 time for 0.4 hr, and extracting for 1.9 hr; extracting the magnolia officinalis coarse powder for 1.5 hours by using a 65% ethanol solution with the volume concentration being 14 times of the mass of the magnolia officinalis coarse powder for the 2 nd time; extracting 3 rd time with 65% ethanol solution with volume concentration 12 times of the coarse powder for 1.0 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume of 10 times mL/g of cortex Magnolia officinalis coarse powder to obtain cortex Magnolia officinalis extract.

3.10 preparation method of mite-clearing acne-relieving anti-inflammation sterilization repair nourishing gel comprises the following steps

a) Weighing 0.8g of Adiantum montanum oil, 0.08g of eucalyptus oil, 0.6g of evening primrose oil, 1.1g of peppermint oil, 0.08g of blumea oil, 0.6g of perilla seed oil, 1.0g of green pepper seed soaking oil, 0.8g of sea buckthorn fruit oil and 1.5g of lithospermum soaking oil, and uniformly stirring to obtain a mixed oil solution A for later use;

b) Weighing 2.0g of sodium alginate, adding the sodium alginate into 32.0mL of distilled water, stirring uniformly, standing for 12.0h to fully swell the sodium alginate to obtain uniform and transparent sodium alginate gel liquid for later use;

c) Weighing 1.5g of an ice crystal forming agent AVC, adding into 83.0mL of distilled water, stirring uniformly, standing for 12.0h to fully swell the mixture, and obtaining a uniform and transparent gel solution of the ice crystal forming agent AVC for later use;

d) Weighing 2.0g of U30 cellulose thickener, adding into 56.0mL of distilled water, stirring uniformly, standing for 12.0h to fully swell the mixture to obtain uniform and transparent U30 cellulose thickener gel liquid for later use;

e) Weighing 0.50g of ethylparaben, adding 5.0mL of 1, 2-propylene glycol, and stirring for dissolving to obtain a preservative solution;

f) Weighing 1.5g of white paeony root extract, 1.0g of baical skullcap root extract, 0.6g of rhodiola root extract, 1.2g of frankincense extract, 1.5g of propolis extract, 1.5g of garlic extract, 2.0g of officinal magnolia bark extract, 1.2g of white vinegar and 0.5g of biological polysaccharide gum, and uniformly mixing to obtain a mixed solution B;

Example 4 (comparative example)

The other steps are the same as the example 3, and the difference is only that the gel liquid formed by adding hydroxypropyl methyl cellulose into the formula specifically comprises the following steps: adding 0.10g of hydroxypropyl methyl cellulose into 10ml of distilled water, fully swelling to obtain hydroxypropyl methyl cellulose gel liquid, and adding the hydroxypropyl methyl cellulose gel liquid in the step h); the prepared mite-clearing anti-acne anti-inflammation sterilization repairing and nourishing gel has the condition of poor use feeling and partial stickiness. No subsequent experiments were performed.

Example 5 (comparative example)

The other steps are the same as those in example 2, and the difference is only that carbomer 941 gel liquid is added into the formula, specifically: 0.15g of carbomer 941 is added into 10ml of distilled water and fully swelled to obtain carbomer 941 gel liquid, and carbomer 941 gel liquid is added in the step h), so that the whole system is thin in consistency. No subsequent experiments were performed.

Example 6 (comparative example)

The rest of the ingredients are the same as example 3, except that under the condition that the dosage of sodium alginate is 2.2g and the dosage of a U30 cellulose thickener is 2.3g, the prepared mite-clearing anti-acne anti-inflammation sterilization repair nourishing gel has good stability, but has poor using feeling and poor using effect, and because the dosages of the sodium alginate and the U30 cellulose thickener are more, the percentage content of effective components in the preparation is reduced, the efficacy is poor, the preparation is greasy, and the score of a result test user after using the mite-clearing anti-acne repair nourishing gel is low.

Example 7

The physical and chemical indexes of the examples 1,2, 3 and 6 are as follows:

7.1 Properties

The mite-clearing, acne-relieving, anti-inflammation, sterilization, restoration and nourishing gel prepared by the method is in lotus root starch color, fine and uniform in texture, proper in viscosity, good in spreading performance and fragrant in smell.

7.2pH check

The mite-clearing, acne-alleviating, anti-inflammatory, bactericidal, repairing and nourishing gel prepared in the embodiments 1,2, 3 and 6 is measured by using a pH test paper, and the measured pH value is 6.0-7.0.

7.3 Cold and Heat test

The mite-clearing, acne-relieving, anti-inflammation, sterilization, restoration, nourishing and condensation prepared in the embodiments 1,2, 3 and 6 is packaged in a transparent bottle and refrigerated in a refrigerator at 4 ℃ for one month and no layering phenomenon is observed; the product is placed in a constant temperature box at 55 ℃ for 24 hours, and the mite-clearing, anti-inflammation, sterilization, restoration, nourishing and condensation products can relieve acne, diminish inflammation, sterilize, repair and have no phenomena of layering, odor change and the like.

7.4 centrifugation experiments

The mite-clearing, acne-relieving, anti-inflammation, sterilization, restoration, nourishing and condensation prepared in the embodiments 1,2, 3 and 6 is packaged in a test tube with a plug, and is centrifuged at 3000r/min for 20min, and the result shows that no layering phenomenon exists.

7.5 Room temperature standing test

The mite-clearing, acne-relieving, anti-inflammation, sterilization, restoration and nourishing gel prepared in the examples 1,2, 3 and 6 is placed in a transparent cosmetic bottle, is kept still at room temperature for 6 months, has no separation phenomenon, and has no odor and texture change after being used.

7.6 irritation and allergy test

The back of a white mouse is cut to remove hairs, and the mite-clearing, anti-acne, anti-inflammation, sterilization, restoration and nourishing gel prepared according to the examples 1,2, 3 and 6 respectively is applied to the parts with the hairs removed, and compared with the parts without the hairs, the result shows that the gel has no irritation and anaphylaxis.

The mite-clearing, anti-acne, anti-inflammation, sterilization, restoration and nourishing gel prepared in examples 1,2, 3 and 6 is applied to the back of the hand of a volunteer (20-35 years old, 60 people), and no redness, eruption or blistering phenomenon appears after observation for 30 min.

7.7 examination of the bacteriostatic Effect

In the same laboratory, the common skin care gel without anti-inflammatory and bacteriostatic components and the mite-clearing, anti-inflammatory, bactericidal, repairing and nourishing gel prepared in example 1 are prepared on the same day, and under the condition that no preservative is added, the sample is kept at 18 +/-2 ℃ for investigation, so that the common skin care preparation has the change and other conditions in one week, the mite-clearing, anti-inflammatory, bactericidal, repairing and nourishing gel for relieving acne and diminishing inflammation still has no change and other deterioration conditions after being placed for six months, and the trial feeling and smell have no obvious change, thereby fully indicating that the mite-clearing, anti-inflammatory, bactericidal, repairing and nourishing gel for relieving acne and clearing away has a certain bacteriostatic effect.

The preparation method of the common skin care gel comprises the following steps: dispersing 1g of an ice crystal forming agent AVC in 55ml of distilled water, fully swelling to form an ice crystal forming agent AVC gel solution, and fully mixing with 3ml of a tremella extract to obtain a common skin care gel;

the preparation method of the tremella extract comprises the following steps: weighing proper amount of tremella coarse powder, heating and refluxing for 3 times: adding water with the amount of 18 times of the coarse powder of Tremella at 1 st time, soaking for 30min, and extracting for 1.5 hr; adding 14 times of water by mass of the tremella coarse powder for the 2 nd time, and extracting for 1.0h; adding water with the amount of 12 times of the weight of the tremella coarse powder for the 3 rd time, and extracting for 1.0h; filtering each time to obtain filtrate, combining the filtrates, performing suction filtration, and concentrating the volume of the filtrate to 6 mL/g of the mass of the tremella coarse powder to obtain tremella extract for later use.

7.8 comprehensive Effect examination

The effects of the mite-clearing agents prepared in examples 1,2, 3 and 6 on relieving acne, diminishing inflammation, sterilizing, repairing, nourishing and condensing are evaluated by using the feeling of trial use of volunteers. A civil investigation and grading method is adopted, 60 volunteers of 20-35 years old are selected as trial objects, the trial objects are divided into three groups at will, the anti-acne-clearing, anti-inflammation, sterilization, restoration and nourishing condensation liquid prepared in the embodiments 1,2, 3 and 6 is respectively applied to the acne and pruritus parts of mites in 2021 year, 7 months and three times a day until symptoms of the affected parts disappear (the acne and pruritus parts of the mites on the whole body can be used, some feedback takes effect within one day, some feedback takes effect within two or three days, and some feedback takes effect within three or four days). The using effects of the ingredients are divided into 5 points: 5 is the highest score, which represents good and very satisfactory; 4, the division is better; 3 is acceptable; when the amount is less than 3 points, the results are not acceptable. The average scores are shown in Table 1 below.

Table 1 comprehensive effect investigation

In conclusion, the mite-clearing, anti-inflammation, sterilization, restoration and nourishing gel prepared by the method disclosed by the invention is fine and uniform in texture, appropriate in viscosity, good in spreadability and fragrant in smell, and has the effects of mildly removing mites, diminishing inflammation, sterilizing and preventing pore blockage, so that acne can be effectively relieved, anti-inflammation, sterilization, restoration and nourishing of damaged skin are realized.

Claims

1. The mite-clearing acne-relieving anti-inflammation sterilization repair nourishing gel is characterized by comprising the following raw materials in parts by weight:

2. the mite-clearing, acne-relieving, anti-inflammatory, bactericidal, repairing and nourishing gel as claimed in claim 1, wherein the green zanthoxylum seed soaking oil is prepared by the following method:

weighing a proper amount of green pepper seed coarse powder, adding seabuckthorn fruit oil which is 3-5 times the weight of the green pepper seed coarse powder, soaking for 3-6 days, performing ultrasonic extraction at the ultrasonic power of 200-600W, heating to 30-60 ℃, performing ultrasonic extraction for 0.5-3.0h, filtering, and taking filtrate to obtain green pepper seed soaking oil for later use;

the lithospermum soaking oil is prepared by the following steps:

weighing a proper amount of lithospermum coarse powder, adding tea seed oil with the weight of 8-10 times of the lithospermum coarse powder, hermetically soaking for 5-7 days, performing ultrasonic extraction with the ultrasonic power of 200-600W, heating to 30-60 ℃, performing ultrasonic extraction for 0.5-3.0h, filtering, and taking filtrate to obtain lithospermum soaking oil for later use.

3. The mite-clearing, acne-alleviating, anti-inflammatory, bactericidal, repairing and nourishing gel as claimed in claim 1, wherein the radix paeoniae alba extracting solution is prepared by the following method:

weighing proper amount of radix paeoniae alba coarse powder, heating and refluxing for extraction for 3 times: adding 12-16 times of water by mass of the white peony root coarse powder at the 1 st time, soaking for 0.5-1.5h, and extracting for 1.5-2.0h; adding water 10-14 times the weight of the white peony root coarse powder for the 2 nd time, and extracting for 1.0-1.5h; adding water 8-12 times the weight of the white peony root coarse powder in the 3 rd time, and extracting for 0.5-1.0h; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume 3-8 times of the weight of radix Paeoniae alba coarse powder to obtain radix Paeoniae alba extractive solution.

4. The mite-removing, acne-relieving, anti-inflammatory, bactericidal, repairing and nourishing gel as claimed in claim 1, wherein the scutellaria baicalensis extracting solution is prepared by the following method:

weighing appropriate amount of Scutellariae radix coarse powder, heating and reflux extracting for 3 times: adding 18-20 times of water by mass of Scutellariae radix coarse powder at 1 st time, soaking for 0.2-0.5 hr, and extracting for 1.0-1.5 hr; adding 14-16 times of water by mass of Scutellariae radix coarse powder at the 2 nd time, and extracting for 1.0-1.5 hr; adding 11-15 times of water by mass of Scutellariae radix coarse powder at 3 rd time, and extracting for 0.5-1.0 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to 8-12 times of the coarse powder mass of Scutellariae radix to obtain Scutellariae radix extractive solution.

5. The mite-clearing, acne-relieving, anti-inflammatory, bactericidal, repairing and nourishing gel as claimed in claim 1, wherein the rhodiola rosea extracting solution is prepared by the following method:

weighing proper amount of rhodiola rosea coarse powder, heating and refluxing for extraction for 3 times: adding water 20-22 times the weight of radix Rhodiolae coarse powder at the 1 st time, soaking for 0.2-0.7 hr, and extracting for 1.5-2.0 hr; adding 16-18 times of water by mass of radix Rhodiolae coarse powder for the 2 nd time, and extracting for 1.0-1.5 hr; adding 10-12 times of water by mass of radix Rhodiolae coarse powder for 3 times, and extracting for 0.5-1.0 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume of 8-12 times of the mass of radix Rhodiolae coarse powder to obtain radix Rhodiolae extractive solution.

6. The mite-clearing, acne-alleviating, anti-inflammatory, bactericidal, repairing and nourishing gel as claimed in claim 1, wherein the frankincense extract is prepared by the following method:

weighing a proper amount of frankincense coarse powder, heating and refluxing the frankincense coarse powder for 3 times by using an ethanol solution with the volume concentration of 75 percent: adding 75% ethanol solution 15-18 times the mass of Olibanum coarse powder at 1 st time, soaking for 0.2-0.5 hr, and extracting for 1.0-1.8 hr; adding 75% ethanol solution with volume concentration 14-17 times the mass of Olibanum coarse powder for 2 times, and extracting for 0.8-1.2 hr; adding 75% ethanol solution 10-12 times the weight of Olibanum coarse powder for 3 times, and extracting for 0.5-1.0h; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to 4-8 times of the mass of Olibanum coarse powder to obtain Olibanum extractive solution.

7. The mite-clearing, acne-relieving, anti-inflammation, sterilization, repair and nourishing gel as claimed in claim 1, wherein the propolis extract is prepared by the following method:

weighing a proper amount of propolis, and heating and refluxing the propolis by using an ethanol solution with the volume concentration of 75% for 3 times: adding 75% ethanol solution 22-24 times the weight of propolis, soaking for 0.2-0.5 hr, and extracting for 1.0-1.5 hr; adding 75% ethanol solution with volume concentration 18-20 times of propolis mass for 2 times, and extracting for 1.0-1.5 hr; adding 75% ethanol solution with volume concentration 14-16 times of propolis mass for 3 times, and extracting for 0.5-1.0 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to volume of 6-10 times of propolis mass mL/g to obtain propolis extractive solution.

8. The mite-removing, acne-relieving, anti-inflammatory, bactericidal, repairing and nourishing gel as claimed in claim 1, wherein the garlic extract is prepared by the following method:

9. The mite-clearing acne-relieving anti-inflammation sterilization-repairing nourishing gel as claimed in claim 1, wherein the magnolia bark extract is prepared by the following method:

weighing an appropriate amount of coarse magnolia bark powder, heating and refluxing the coarse magnolia bark powder by using an ethanol solution with the volume concentration of 65 percent for 3 times: soaking in 65% ethanol solution 16-20 times the weight of Magnolia officinalis coarse powder for 1 time for 0.2-0.4 hr, and extracting for 1.2-2.0 hr; extracting the 2 nd coarse powder with 10-14 times of 65% ethanol solution by volume for 1.0-1.5 hr; extracting 3 rd time with 65% ethanol solution with volume concentration of 8-12 times the weight of Magnolia officinalis coarse powder for 0.5-1.0 hr; filtering each time to obtain filtrate, mixing filtrates, vacuum filtering, and concentrating the filtrate to 6-10 times of the coarse powder mass of cortex Magnolia officinalis to obtain cortex Magnolia officinalis extractive solution.

10. The preparation method of the mite-clearing, acne-relieving, anti-inflammation, sterilization-repairing, nourishing and condensation gel as claimed in any one of claims 1 to 9, is characterized by comprising the following steps:

b) Weighing 1.0-2.0g of sodium alginate, adding into 20.0-33.0mL of distilled water, stirring uniformly, standing for 8.0-12.0h to fully swell to obtain uniform and transparent sodium alginate gel liquid for later use;